171,138 results match your criteria Asian Women[Journal]


Bavachin attenuates LPS-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages.

Phytomedicine 2018 Dec 10;59:152785. Epub 2018 Dec 10.

Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. Electronic address:

Background: Bavachin is a natural product isolated from Psoralea corylifolia L. that has been applied as a traditional medicine in Asian countries. However, the anti-inflammatory effects of bavachin on LPS-induced inflammation and NLRP3 inflammasome activation by macrophages remain unclear. Read More

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http://dx.doi.org/10.1016/j.phymed.2018.12.008DOI Listing
December 2018

Lung Cancer Risk in Never Smokers of European Descent is Associated with Genetic Variation in the 515.33 TERT-CLPTM1L Region.

J Thorac Oncol 2019 Apr 19. Epub 2019 Apr 19.

Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH 03756, USA. Electronic address:

Introduction: Inherited susceptibility to lung cancer risk in never smokers is poorly understood. The major reason for this gap in knowledge is that this disease is relatively uncommon (except in Asians), making it difficult to assemble an adequate study sample. In this study we conducted a genome-wide association study (GWAS) on the largest, to date, set of European-descent never smokers with lung cancer. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193028
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http://dx.doi.org/10.1016/j.jtho.2019.04.008DOI Listing
April 2019
1 Read

One Modification, Two Functions: Single Ni-modified Light-Driven Microrockets with Both Efficient Propulsion and Steerable Motion.

Chem Asian J 2019 Apr 22. Epub 2019 Apr 22.

CHINA.

Efficient propulsion and effective direction control are essential for self-propelled micro/nanomotors. We demonstrate a brand new "two-in-one" strategy for making attractive light-driven micro/nanomotors. We make use of the metallic and magnetic properties of low-cost Ni and incorporate just single Ni layer into ZnO-based microrockets, so that such ZnO-Ni microrockets can be both efficiently propelled by low energy (low light intensities and fuel concentrations) and effectively steered by a magnetic field. Read More

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http://dx.doi.org/10.1002/asia.201900348DOI Listing

Rituximab for treatment of refractory insulin autoimmune syndrome associated with non-Hodgkin B-cell lymphoma.

Clin Endocrinol (Oxf) 2019 Apr 22. Epub 2019 Apr 22.

Southern Adelaide Diabetes and Endocrine Services, Marion, AUSTRALIA.

Insulin autoimmune syndrome (IAS or Hirata's Disease) is a rare cause of spontaneous hypoglycaemia. In IAS circulating autoantibodies bind endogenous insulin rendering insulin inactive. These complexes later dissociate in an unregulated manner resulting in hypoglycaemia. Read More

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http://dx.doi.org/10.1111/cen.13998DOI Listing

Race/Ethnicity-specific Disparities in In-Hospital Mortality and Hospital Charges Among Inflammatory Bowel Disease-related Hospitalizations in the United States.

J Clin Gastroenterol 2019 Apr 17. Epub 2019 Apr 17.

Division of Gastroenterology and Hepatology, Alameda Health System, Highland Hospital, Oakland, CA.

Goal: The goal of this study was to evaluate disparities in hospital outcomes among inflammatory bowel disease (IBD) related hospitalizations in the United States with a focus on ethnicity-specific disparities.

Background: IBD-related hospitalizations contribute to significant morbidity and health care economic burden.

Methods: IBD-related hospitalizations (identified with ICD-9) among US adults were evaluated using 2007 to 2013 Nationwide Inpatient Sample. Read More

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http://Insights.ovid.com/crossref?an=00004836-900000000-9773
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http://dx.doi.org/10.1097/MCG.0000000000001204DOI Listing
April 2019
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High contiguity whole genome sequence and gene annotation resource for two Venturia nashicola isolates.

Mol Plant Microbe Interact 2019 Apr 22. Epub 2019 Apr 22.

Pohang University of Science and Technology, 34995, Department of Life Sciences , 77 CheongAm-Ro , Nam-Gu , Pohang, GyeongBuk, Korea (the Republic of) , 37673 ;

Venturia nashicola is a fungal pathogen that causes Asian pear scab disease. This pathogen is of particular importance in Northeast Asian countries, where Asian pears are grown industrially. Scab disease in Asian pear is currently controlled by fungicide spraying and this situation calls for developing scab resistant cultivars. Read More

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http://dx.doi.org/10.1094/MPMI-03-19-0072-ADOI Listing

Does transfusion of Asian-type DEL red blood cells to D- recipients cause D alloimmunization?

Transfusion 2019 Apr 22. Epub 2019 Apr 22.

Department of Pathology and Laboratory Medicine, MedStar Georgetown University Hospital, Washington, DC.

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http://dx.doi.org/10.1111/trf.15323DOI Listing

Left atrial appendage closure with WATCHMAN in Asian patients: 2 year outcomes from the WASP registry.

Int J Cardiol Heart Vasc 2019 Jun 9;23:100358. Epub 2019 Apr 9.

National Heart Institute, Kuala Lumpur, Malaysia.

Background: Left atrial appendage closure is a non-pharmacological alternative for stroke prevention in high-risk non-valvular atrial fibrillation patients, but has not been widely studied in Asian patients. The prospective WASP registry assessed real-world outcomes for patients undergoing WATCHMAN implant in the Asia-Pacific region.

Methods: Data were collected from consecutive patients across 9 centres. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23529067193002
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http://dx.doi.org/10.1016/j.ijcha.2019.100358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458488PMC
June 2019
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Poorly differentiated adenocarcinoma of an unknown primary with a thyroid tumour and an aggressive course: thyroid or lung carcinoma?

Oxf Med Case Reports 2019 Apr 16;2019(4):omy129. Epub 2019 Apr 16.

Division of Internal Medicine, Department of Internal Medicine, Chitose City Hospital, Hokkaido 066-8550, Japan.

Cancers of unknown primary (CUPs) are challenging for physicians to diagnose and treat. Metastases to the thyroid gland are rare, representing less than 1% of all thyroid malignancies. Here, we report a case of a 69-year-old Asian man who had both thyroid gland and lymph node enlargement in the neck and shoulders but no nodules/tumours in the lung field. Read More

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http://dx.doi.org/10.1093/omcr/omy129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467094PMC

Silenced PITX1 promotes chemotherapeutic resistance to 5-fluorocytosine and cisplatin in gastric cancer cells.

Exp Ther Med 2019 May 1;17(5):4046-4054. Epub 2019 Apr 1.

Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, Jiangsu 210009, P.R. China.

Resistance to chemotherapeutic drugs leads to a poor prognosis in gastric cancer (GC). The present study aimed to assess the association between pituitary homeobox paired homeodomain transcription 1 (PITX1) expression and the sensitivity of GC cells to the chemotherapeutic drugs 5-fluorouracil (5-FU) and cisplatin (CDDP). In the present study, the gastric cancer cell lines GES-1, AGS, BGC-823, MCG-803 and SGC-7901 were used. Read More

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http://dx.doi.org/10.3892/etm.2019.7459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468935PMC

Loneliness correlates and associations with health variables in the general population in Indonesia.

Int J Ment Health Syst 2019 10;13:24. Epub 2019 Apr 10.

1North West University, Potchefstroom, South Africa.

Background: Loneliness has been commonly reported in high-income countries, while less is known about loneliness in Association of the Southeast Asian Nations (ASEAN) member states, in particular in Indonesia.

Objective: The aim of the study was to estimate the prevalence of loneliness, its correlates and associations with health variables in a national survey in the general population in Indonesia.

Methods: In the Indonesia Family Life Survey (IFLS-5) in 2014-2015, 31,447 participants 15 years and older (median age 35. Read More

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http://dx.doi.org/10.1186/s13033-019-0281-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456978PMC

Applicability of Trichoscopy in Scalp Seborrheic Dermatitis.

Int J Trichology 2019 Mar-Apr;11(2):43-48

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia - dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.

Introduction: Seborrheic dermatitis (SD) is a chronic-recidive inflammatory skin disorder with predilection in areas rich of sebaceous gland. The most common clinical manifestations are pruritus and scales. Although SD can be diagnosed without special tools, other examinations may be needed to determine additional specific therapy. Read More

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http://dx.doi.org/10.4103/ijt.ijt_86_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463453PMC

Mantle Flow and Deforming Continents: From India-Asia Convergence to Pacific Subduction.

Tectonics 2018 Sep 6;37(9):2887-2914. Epub 2018 Sep 6.

C.R.P.G. Université de Lorraine Vandoeuvre-les-Nancy France.

The formation of mountain belts or rift zones is commonly attributed to interactions between plates along their boundaries, but the widely distributed deformation of Asia from Himalaya to the Japan Sea and other back-arc basins is difficult to reconcile with this notion. Through comparison of the tectonic and kinematic records of the last 50 Ma with seismic tomography and anisotropy models, we show that the closure of the former Tethys Ocean and the extensional deformation of East Asia can be best explained if the asthenospheric mantle transporting India northward, forming the Himalaya and the Tibetan Plateau, reaches East Asia where it overrides the westward flowing Pacific mantle and contributes to subduction dynamics, distributing extensional deformation over a 3,000-km wide region. This deep asthenospheric flow partly controls the compressional stresses transmitted through the continent-continent collision, driving crustal thickening below the Himalayas and Tibet and the propagation of strike-slip faults across Asian lithosphere further north and east, as well as with the lithospheric and crustal flow powered by slab retreat east of the collision zone below East and SE Asia. Read More

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http://dx.doi.org/10.1029/2018TC005036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472563PMC
September 2018

Implementation of provider payment system reforms in the age of universal health coverage: a realist review of evidence from Asian developing countries.

J Health Serv Res Policy 2019 Apr 20:1355819619842305. Epub 2019 Apr 20.

3 Visiting Professor, Lee Kuan Yew School of Public Policy, National University of Singapore, Singapore.

Objective: Launched to assist in achieving universal health coverage, provider payment reform (PPR) is one of the most important policy tools deployed to transform incentives within a health system that is plagued with allocative inefficiency and high out-of-pocket payments to one that is able to deliver basic services and be cost-efficient. However, the black box of such reform - that is, the contexts in which reform operates, the mechanisms by which it changes health systems and behaviour within health systems, and the outcome patterns that arise from - remains unexplored. This review aims to examine the implementation mechanisms underlying PPR in Asian developing countries. Read More

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http://dx.doi.org/10.1177/1355819619842305DOI Listing

"They Don't Trust Us": The Influence of Perceptions of Inadequate Nursing Home Care on Emergency Department Transfers and the Potential Role for Telehealth.

Clin Nurs Res 2019 Apr 21:1054773819835015. Epub 2019 Apr 21.

4 Division of Geriatrics, University of California, San Francisco, CA, USA.

In this descriptive, qualitative study, we conducted eight focus groups with diverse informal and formal caregivers to explore their experiences/challenges with nursing home (NH) to emergency department (ED) transfers and whether telehealth might be able to mitigate some of those concerns. Interviews were transcribed and analyzed using a grounded theory approach. Transfers were commonly viewed as being influenced by a perceived lack of trust in NH care/capabilities and driven by four main factors: questioning the quality of NH nurses' assessments, perceptions that physicians were absent from the NH, misunderstandings of the capabilities of NHs and EDs, and perceptions that responses to medical needs were inadequate. Read More

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http://dx.doi.org/10.1177/1054773819835015DOI Listing

Clinical Observations and the Anatomical Basis of Blindness After Facial Hyaluronic Acid Injection.

Aesthetic Plast Surg 2019 Apr 21. Epub 2019 Apr 21.

Department of Plastic and Reconstructive Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, 310014, China.

Background: Blindness or visual loss is the most serious complication resulting from facial hyaluronic acid (HA) injection. In this study, three recent clinical cases were analyzed, and the relevant anatomy of cadavers was evaluated to investigate the mechanism behind visual impairment due to HA injection.

Methods: Three patients with different extents of visual loss after HA injection were studied. Read More

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http://dx.doi.org/10.1007/s00266-019-01374-wDOI Listing

Obesity risk in women of childbearing age in New Zealand: a nationally representative cross-sectional study.

Int J Public Health 2019 Apr 22. Epub 2019 Apr 22.

GeoHealth Laboratory (Te Taiwhenua o te Hauora), Geospatial Research Institute (Toi Hangarau), University of Canterbury (Te Whare Wānanga o Waitaha), Christchurch, New Zealand.

Objectives: To investigate risk factors for women with obesity of childbearing age.

Methods: A cross-sectional survey of New Zealand women (15-49 years) with measured height and weight was used [unweighted (n = 3625) and weighted analytical sample (n = 1,098,372)] alongside sociodemographic-, behavioural- and environmental-level predictors. Multilevel logistic regression weighted for non-response of height and weight data was used. Read More

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http://dx.doi.org/10.1007/s00038-019-01239-8DOI Listing

Comparison of diagnostic efficacy between transrectal and transperineal prostate biopsy: A propensity score-matched study.

Asian J Androl 2019 Apr 19. Epub 2019 Apr 19.

Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.

This study compared the diagnostic efficacy of transrectal ultrasound (TRUS)-guided prostate biopsy (TRBx) and transperineal prostate biopsy (TPBx) in patients with suspected prostate cancer (PCa). We enrolled 2962 men who underwent transrectal (n = 1216) or transperineal (n = 1746) systematic 12-core prostate biopsy. Clinical data including age, prostate-specific antigen (PSA) level, and prostate volume (PV) were recorded. Read More

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http://dx.doi.org/10.4103/aja.aja_16_19DOI Listing

Multi-center evaluation of oxidation-reduction potential by the MiOXSYS in males with abnormal semen.

Asian J Androl 2019 Apr 16. Epub 2019 Apr 16.

Tulane University, New Orleans, LA 70118, USA.

According to the World Health Organization (WHO), oxidative stress (OS) is a significant contributor to male infertility. Seminal OS can be measured by a number of assays, all of which are either costly or time sensitive and/or require large semen volume and complex instrumentation. One less expensive alternative is to quantify the oxidation-reduction potential (ORP) with the MiOXSYS. Read More

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http://dx.doi.org/10.4103/aja.aja_5_19DOI Listing

Reduced semen quality in patients with testicular cancer seminoma is associated with alterations in the expression of sperm proteins.

Asian J Androl 2019 Apr 16. Epub 2019 Apr 16.

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.

Testicular cancer seminoma is one of the most common types of cancer among men of reproductive age. Patients with this condition usually present reduced semen quality, even before initiating cancer therapy. However, the underlying mechanisms by which testicular cancer seminoma affects male fertility are largely unknown. Read More

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http://dx.doi.org/10.4103/aja.aja_17_19DOI Listing

Proteomic analysis of seminal plasma from bilateral varicocele patients indicates an oxidative state and increased inflammatory response.

Asian J Androl 2019 Apr 16. Epub 2019 Apr 16.

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.

Seminal plasma is a rich source of proteins and serves as an ideal sample for proteomic analysis of male infertility. In varicocele-associated infertility, the contributory role of seminal plasma proteins specific to unilateral and bilateral varicocele is not clear. Furthermore, there is a lack of specific protein biomarker to differentiate bilateral from unilateral varicocele. Read More

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http://dx.doi.org/10.4103/aja.aja_121_18DOI Listing

IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.

Am J Hum Genet 2019 Apr 6. Epub 2019 Apr 6.

Center for Data Sciences, Harvard Medical School, Boston, MA 02115, USA; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA; Graduate School of Arts and Sciences, Harvard University, Cambridge, MA 02138, USA; Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK. Electronic address:

Despite significant progress in annotating the genome with experimental methods, much of the regulatory noncoding genome remains poorly defined. Here we assert that regulatory elements may be characterized by leveraging local epigenomic signatures where specific transcription factors (TFs) are bound. To link these two features, we introduce IMPACT, a genome annotation strategy that identifies regulatory elements defined by cell-state-specific TF binding profiles, learned from 515 chromatin and sequence annotations. Read More

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http://dx.doi.org/10.1016/j.ajhg.2019.03.012DOI Listing

Shared Genetic Etiology of Hwabyung (Anger Syndrome) and Somatization Symptoms in South Korean Adolescent and Young Adult Twins.

Twin Res Hum Genet 2019 Apr 22:1-6. Epub 2019 Apr 22.

Department of Neuropsychiatry,College of Korean Medicine, Kyunghee University Korean Medicine Hospital at Gangdong,Seoul,South Korea.

Somatization is known to be more prevalent in Asian than in Western populations. Using a South Korean adolescent and young adult twin sample (N = 1754; 367 monozygotic male, 173 dizygotic male, 681 monozygotic female, 274 dizygotic female and 259 opposite-sex dizygotic twins), the present study aimed to estimate heritability of somatization and to determine common genetic and environmental influences on somatization and hwabyung (HB: anger syndrome). Twins completed self-report questionnaires of the HB symptoms scale and the somatization scale via a telephone interview. Read More

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https://www.cambridge.org/core/product/identifier/S183242741
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http://dx.doi.org/10.1017/thg.2019.6DOI Listing
April 2019
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Spearman's hypothesis tested comparing Korean young adults with various other groups of young adults on the items of the Advanced Progressive Matrices.

J Biosoc Sci 2019 Apr 22:1-38. Epub 2019 Apr 22.

1National Research Center for Dementia,Chosun University,Gwangju,Korea.

Spearman's hypothesis tested at the subtest level of an IQ battery states that differences between races on the subtests of an IQ battery are a function of the g loadings of these subtests, such that there are small differences between races on subtests with low g loadings and large differences between races on subtests with high g loadings. Jensen (1998) stated that Spearman's hypothesis is a law-like phenomenon. It has also been confirmed many times at the level of items of the Raven's Progressive Matrices. Read More

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http://dx.doi.org/10.1017/S0021932019000026DOI Listing

[Levels of skeletal muscle mass and handgrip strength in adults from 10 regions of China].

Zhonghua Liu Xing Bing Xue Za Zhi 2019 Apr;40(4):376-381

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.

To describe the regional and population-related differences in skeletal muscle mass and handgrip strength across the 10 regions of China. 24 533 participants aged 38-88 years from the second resurvey of China Kadoorie Biobank were included in our analyses. Appendicular and trunk skeletal muscle mass were assessed using the bioelectrical impedance analysis (TANITA). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2019.04.002DOI Listing

Pharmacovigilance Systems in Arab Countries: Overview of 22 Arab Countries.

Drug Saf 2019 Apr 20. Epub 2019 Apr 20.

College of Pharmacy, Department of Clinical Pharmacy, University of Hail, P.O. Box 6166, Hail, 81442, Saudi Arabia.

Pharmacovigilance has received much attention in Arab countries recently due to the development of new regulations. However, there are differences in the progression of pharmacovigilance systems by regulatory agencies in these countries because only some are able to meet the requirements for conducting pharmacovigilance activities. Only 45% of Arab countries are official members of the World Health Organization (WHO) Collaborating Centre for International Drug Monitoring. Read More

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http://link.springer.com/10.1007/s40264-019-00807-4
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http://dx.doi.org/10.1007/s40264-019-00807-4DOI Listing
April 2019
3 Reads

Non-fracture stem vs fracture stem of reverse total shoulder arthroplasty in complex proximal humeral fracture of asian elderly.

Arch Orthop Trauma Surg 2019 Apr 20. Epub 2019 Apr 20.

Department of Orthopaedic Surgery, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 64, Daeheung-ro, Jung-gu, Daejeon, 34943, South Korea.

Purpose: Fracture stem of the reverse total shoulder arthroplasty (RTSA) was designed for better tuberosity bone healing for the proximal bone defect of complex proximal humeral fractures (PHF). Our purpose was to compare the clinical and radiological outcomes of patients using fracture stem vs non-fracture (conventional) stem of RTSA in complex PHF of elderly patients.

Methods: Between 2008 March and 2017 June, 48 patients who had undergone an RTSA with non-fracture or fracture stem for complex PHF with a minimum 18 months of follow-up were evaluated. Read More

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http://dx.doi.org/10.1007/s00402-019-03190-yDOI Listing

Pharmacokinetics of Single Doses of BI 425809 in Healthy Chinese and Japanese Subjects: A Randomized Study.

Clin Ther 2019 Apr 17. Epub 2019 Apr 17.

Inje University Busan Paik Hospital, Busan, South Korea.

Purpose: This study's primary goal was to evaluate the safety profile, tolerability, pharmacokinetics, and dose proportionality of BI 425809, a potent and selective inhibitor of glycine transporter 1, in healthy Chinese and Japanese subjects.

Methods: This single center, double-blind, single-rising dose study conducted in Korea randomly assigned (3:1) subjects within each ethnic subgroup (Chinese and Japanese) to receive a single dose of BI 425809 (10, 25, or 50 mg) or placebo. The primary end point was number (%) of subjects with drug-related adverse events (AEs). Read More

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http://dx.doi.org/10.1016/j.clinthera.2019.03.014DOI Listing

Outcomes by Gender and Ethnicity After Percutaneous Coronary Intervention.

Am J Cardiol 2019 Mar 19. Epub 2019 Mar 19.

Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

Limited data on gender differences by ethnicity after percutaneous coronary intervention (PCI) exist. In this prospective cohort study, we examined gender differences in 1-year outcomes among patients from 4 ethnic groups who underwent PCI from 2010 to 2016 at a tertiary center. The primary outcome was 1-year major adverse cardiovascular events (MACE) defined as composite of all-cause death, nonfatal myocardial infarction (MI), or target lesion revascularization. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029149193031
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http://dx.doi.org/10.1016/j.amjcard.2019.03.019DOI Listing
March 2019
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Genome-wide identification of ATP-binding cassette transporters and expression profiles in the Asian citrus psyllid, Diaphorina citri, exposed to imidacloprid.

Comp Biochem Physiol Part D Genomics Proteomics 2019 Apr 11;30:305-311. Epub 2019 Apr 11.

Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing 400716, China; State Cultivation Base of Crop Stress Biology for Southern Mountainous Land of Southwest University, International Joint Laboratory of China-Belgium on Sustainable Crop Pest Control, Academy of Agricultural Sciences, Southwest University, Chongqing 400716, China. Electronic address:

ATP-binding cassette (ABC) transporters belong to a large protein superfamily found in both prokaryotic and eukaryotic organisms. In arthropods, ABC transporters are involved in defense and resistance to insecticides. The Asian citrus psyllid (ACP), Diaphorina citri, is a major vector of the Huanglongbing pathogen (Candidatus Liberibacter asiaticus) worldwide. Read More

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http://dx.doi.org/10.1016/j.cbd.2019.04.003DOI Listing

Patterns of outdoor exposure to heat in three South Asian cities.

Sci Total Environ 2019 Apr 9;674:264-278. Epub 2019 Apr 9.

Wageningen University and Research, Wageningen Environmental Research, Wageningen, the Netherlands; London School of Economics and Political Science, Grantham Research Institute, London, United Kingdom.

Low socio-economic status has been widely recognized as a significant factor in enhancing a person's vulnerability to climate change including vulnerability to changes in temperature. Yet, little is known about exposure to heat within cities in developing countries, and even less about exposure within informal neighbourhoods in those countries. This paper presents an assessment of exposure to outdoor heat in the South Asian cities Delhi, Dhaka, and Faisalabad. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697193160
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http://dx.doi.org/10.1016/j.scitotenv.2019.04.087DOI Listing
April 2019
1 Read

Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.

Mol Cell Biochem 2019 Apr 20. Epub 2019 Apr 20.

Department of Cell and Molecular Biology, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialties Centre, ICMR-Centre for Advanced Research on Diabetes, Gopalapuram, Chennai, 600086, India.

There is a striking interaction of genes and environment in the etiology of type 2 diabetes mellitus (T2DM). While endocrine disrupting chemicals (EDCs) like bisphenol-A (BPA) have received special attention for their mechanistic role in metabolic disruption, there is a lack of clinically relevant data on BPA levels in Asian Indians, a population which is more susceptible to type 2 diabetes mellitus (T2DM) and cardiovascular diseases. Therefore, we measured systemic levels of BPA in patients with T2DM compared to individuals with normal glucose tolerance (n = 30 each). Read More

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http://dx.doi.org/10.1007/s11010-019-03540-9DOI Listing

Characteristics and association with survival of respiratory-related hospitalization in Japanese idiopathic pulmonary fibrosis patients.

Respir Investig 2019 Apr 16. Epub 2019 Apr 16.

Department of Respiratory Medicine and Allergology, Kindai University, Faculty of Medicine, Osakasayama, Osaka, Japan. Electronic address:

Background: The characteristics and significance of respiratory-related hospitalization in patients with idiopathic pulmonary fibrosis (IPF) in Asian countries remain unknown. The purpose of this study was to define the characteristics of respiratory-related hospitalization and to inspect the relationship between respiratory-related hospitalization and subsequent survival in patients with IPF in Japanese general practice.

Methods: Patients with IPF who underwent clinical evaluation between February 2008 and August 2017 were screened. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22125345183031
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http://dx.doi.org/10.1016/j.resinv.2019.03.005DOI Listing
April 2019
3 Reads

Factors affecting functional outcomes following mangled lower limb injury.

Asian J Surg 2019 Apr 16. Epub 2019 Apr 16.

Division of Plastic and Reconstructive Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10159584193008
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http://dx.doi.org/10.1016/j.asjsur.2019.01.021DOI Listing
April 2019
1 Read
0.758 Impact Factor

Pectus excavatum repair using bridge fixation system.

Asian Cardiovasc Thorac Ann 2019 Apr 19:218492319846733. Epub 2019 Apr 19.

Department of Thoracic Surgery, Choray Hospital, Ho Chi Minh City, Vietnam.

Background: The stability of the pectus bar is an important determinant of the success of pectus excavatum repair surgery. In practice, several different types of fixation method are in use for stabilizing pectus bars. The aim of this study was to compare the performance of the bridge fixation system with previous fixation systems for stabilizing pectus bars. Read More

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http://dx.doi.org/10.1177/0218492319846733DOI Listing

Performance Evaluation of a Thermophilic Anaerobic Membrane Bioreactor for Palm Oil Wastewater Treatment.

Membranes (Basel) 2019 Apr 18;9(4). Epub 2019 Apr 18.

Department of Energy, Environment and Climate Change, School of Environment, Resources and Development, Asian Institute of Technology, P.O. Box 4, Khlong Luang, Pathumthani 12120, Thailand.

Anaerobic treatment processes have achieved popularity in treating palm oil mill effluent due to its high treatability and biogas generation. The use of externally submerged membranes with anaerobic reactors promotes the retention of the biomass in the reactor. This study was conducted in thermophilic conditions with the Polytetrafluoroethylene hollow fiber (PTFE-HF) membrane which was operated at 55 °C. Read More

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http://dx.doi.org/10.3390/membranes9040055DOI Listing

A narrative synthesis of possible causes and risk factors of hoarding behaviours.

Asian J Psychiatr 2019 Apr 8;42:104-114. Epub 2019 Apr 8.

Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, 539747, Singapore. Electronic address:

Background: Hoarding is a disorder characterized by excessive acquisition and persistent difficulty in discarding possessions. The behaviour has adverse emotional, physical, social, financial, and legal outcomes for the person with the disorder and family members, and might pose a significant public health problem. Hoarding has been included as a distinct disorder in the Diagnostic and Statistical Manual of Mental Disorders Fifth edition (DSM-5). Read More

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http://dx.doi.org/10.1016/j.ajp.2019.04.001DOI Listing

Psychological Distress among Adolescents in Laos, Mongolia, Nepal, and Sri Lanka.

Asian Nurs Res (Korean Soc Nurs Sci) 2019 Apr 16. Epub 2019 Apr 16.

Hanyang University, College of Medicine, Department of Preventive Medicine; Hanyang University, Institute for Health and Society, Seoul, Republic of Korea.

Purpose: The purpose of this study was to explore psychological distress and examine the relationship between this distress and individual, family, and school factors among adolescents in four low- and middle-income countries (LAMICs) in Asia (i.e., Laos, Mongolia, Nepal, and Sri Lanka). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19761317183023
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http://dx.doi.org/10.1016/j.anr.2019.04.001DOI Listing
April 2019
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Phylogenetic analysis of partial pre-membrane and envelope sequences of dengue viruses circulating in India.

Int J Infect Dis 2019 Apr 16. Epub 2019 Apr 16.

Dept. of Clinical Virology, Christian Medical College, Vellore 632004, Tamil Nadu, India. Electronic address:

Objective: Phylogenetic characteristics of circulating Indian dengue viruses (DENV) were analysed using partial pre-membrane (PrM) and envelope (E) sequences. An immunodominant region was analysed for mutations and alignment with common DENV PCR primers and probes was determined.

Methods: Published Indian PrM and E DENV sequences were analysed with hitherto unpublished PrM sequences from this study site. Read More

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http://dx.doi.org/10.1016/j.ijid.2019.04.010DOI Listing

The association between alcohol metabolism and genetic variants of ADH1A, SRPRB, and PGM1 in Korea.

Alcohol 2019 Apr 16. Epub 2019 Apr 16.

Division of Endocrine and Metabolic Disease, Center for Biomedical Sciences, Korea National Institute of Health, Cheongju, Chungbuk, 28159, South Korea.

Background: Excessive alcohol consumption is a major public health problem in East Asian countries. Alcohol use leads to a cascade of problems including increased chances of risky behavior and wide range of negative health consequences from alcoholic liver disease to upper gastric and liver cancer. These alcohol effects are known to be influenced by ethnic variability and genetics. Read More

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http://dx.doi.org/10.1016/j.alcohol.2019.03.004DOI Listing

Trends in cervical cancer incidence rates by age, race/ethnicity, histological subtype, and stage at diagnosis in the United States.

Prev Med 2019 Apr 16. Epub 2019 Apr 16.

Surveillance and Health Services Research, American Cancer Society, Atlanta, GA, United States of America.

Recent trends of cervical cancer incidence by histology and age in the United States (U.S.) have not been reported. Read More

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http://dx.doi.org/10.1016/j.ypmed.2019.04.010DOI Listing

Genome-wide diversity and demographic dynamics of Cameroon goats and their divergence from east African, north African, and Asian conspecifics.

PLoS One 2019 19;14(4):e0214843. Epub 2019 Apr 19.

Biosciences Eastern and Central Africa-International Livestock Research Institute (BecA-ILRI) Hub, Nairobi, Kenya.

Indigenous goats make significant contributions to Cameroon's national and local economy, but little effort has been devoted to identifying the populations. Here, we assessed the genetic diversity and demographic dynamics of Cameroon goat populations using mitochondrial DNA (two populations) and autosomal markers (four populations) generated with the Caprine 50K SNP chip. To infer genetic relationships at continental and global level, genotype data on six goat populations from Ethiopia and one population each from Egypt, Morocco, Iran, and China were included in the analysis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214843PLOS

Reducing ethnic disparity in access to high-quality HLA-matched cord blood units for transplantation: analysis of the Canadian Blood Services' Cord Blood Bank inventory.

Transfusion 2019 Apr 19. Epub 2019 Apr 19.

Canadian Blood Services' Cord Blood Bank, Ottawa, Ontario.

Background: Launched in 2013, Canadian Blood Services' Cord Blood Bank (CBS' CBB) has built a high-quality, ethnically diverse cord blood repository that aims to reduce ethnic disparity in accessing suitable units for transplantation.

Methods And Results: As of December 2016, 2000 units have been banked. The self-reported maternal ethnicity was 58% non-Caucasian. Read More

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http://dx.doi.org/10.1111/trf.15313DOI Listing

Association of Diabetes With All-Cause and Cause-Specific Mortality in Asia: A Pooled Analysis of More Than 1 Million Participants.

JAMA Netw Open 2019 Apr 5;2(4):e192696. Epub 2019 Apr 5.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

Importance: Asia is home to the largest diabetic populations in the world. However, limited studies have quantified the association of diabetes with all-cause and cause-specific mortality in Asian populations.

Objectives: To evaluate the association of diabetes with all-cause and cause-specific mortality in Asia and to investigate potential effect modifications of the diabetes-mortality associations by participants' age, sex, education level, body mass index, and smoking status. Read More

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2019.2696DOI Listing
April 2019
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Fine scale genomic signals of admixture and alien introgression among Asian rice landraces.

Genome Biol Evol 2019 Apr 19. Epub 2019 Apr 19.

UMR AGAP, CIRAD, F-34398 Montpellier, France.

Modern rice cultivars are adapted to a range of environmental conditions and human preferences. At the root of this diversity is a marked genetic structure, owing to multiple foundation events. Admixture and recurrent introgression from wild sources have played upon this base to produce the myriad adaptations existing today. Read More

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https://academic.oup.com/gbe/advance-article/doi/10.1093/gbe
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http://dx.doi.org/10.1093/gbe/evz084DOI Listing
April 2019
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Mixed Mycobacterium tuberculosis Lineage Infection in 2 Elephants, Nepal.

Emerg Infect Dis 2019 May;25(5):1031-1032

Tuberculosis in elephants is primarily caused by Mycobacterium tuberculosis. We identified mixed M. tuberculosis lineage infection in 2 captive elephants in Nepal by using spoligotyping and large sequence polymorphism. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1898_article.htm
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http://dx.doi.org/10.3201/eid2505.181898DOI Listing
May 2019
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A systematic review of observational studies of trifluridine/tipiracil (TAS-102) for metastatic colorectal cancer.

Acta Oncol 2019 Apr 19:1-9. Epub 2019 Apr 19.

e Department of Oncology , Zealand University Hospital , Roskilde , Denmark.

Background: The treatment options for patients with therapy refractory metastatic colorectal cancer (mCRC) are sparse. TAS-102 (FTD/TPI) is a new oral anti-tumour agent composed of a nucleoside analogue, trifluridine, and a thymidine phosphorylase inhibitor, tipiracil, indicated for patients with mCRC who are refractory to standard therapies. This study summarizes published and unpublished experience with FTD/TPI in clinical practice settings. Read More

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http://dx.doi.org/10.1080/0284186X.2019.1605192DOI Listing

Sesquiterpenes from an Eastern African Medicinal Mushroom Belonging to the Genus Sanghuangporus.

J Nat Prod 2019 Apr 19. Epub 2019 Apr 19.

Department of Microbial Drugs , Helmholtz Centre for Infection Research (HZI), and German Centre for Infection Research (DZIF) , Partner Site Hannover/Braunschweig, Inhoffenstrasse 7 , 38124 Braunschweig , Germany.

During the course of searching for new anti-infective and other biologically active secondary metabolites from Kenyan basidiomycetes, 13 previously undescribed metabolites, (6 R,7 S,10 R)-7,10-epoxy-7,11-dimethyldodec-1-ene-6,11-diol (1) and 12 sesquiterpenes named elgonenes A-L (2-13), and the known compound P-coumaric acid (14) were isolated from a basidiomycete collected in Mount Elgon Natural Reserve. The producing organism represents a new species of the genus Sanghuangporus, which is one of the segregates of the important traditional Asian medicinal mushrooms that were formerly known as the " Inonotus linteus" complex. The structure elucidation of compounds 1-13, based on 2D NMR spectroscopy, high-resolution mass spectrometry, and other spectral methods, and their antibacterial, antifungal, and cytotoxic activities are reported. Read More

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http://pubs.acs.org/doi/10.1021/acs.jnatprod.8b01086
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http://dx.doi.org/10.1021/acs.jnatprod.8b01086DOI Listing
April 2019
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Pre-diagnostic blood levels of organochlorines and risk of non-Hodgkin lymphoma in three prospective cohorts in China and Singapore.

Int J Cancer 2019 Apr 19. Epub 2019 Apr 19.

Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Rockville, MD, USA.

Specific organochlorines (OCs) have been associated with non-Hodgkin lymphoma (NHL) with varying degrees of evidence. These associations have not been evaluated in Asia, where the high exposure and historical environmental contamination of certain OC pesticides (e.g. Read More

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http://dx.doi.org/10.1002/ijc.32350DOI Listing

Longitudinal Analysis Between Maternal Feeding Practices and Body Mass Index (BMI): A Study in Asian Singaporean Preschoolers.

Front Nutr 2019 2;6:32. Epub 2019 Apr 2.

Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore, Singapore.

Bidirectional studies between maternal feeding practices with subsequent child weight are limited, with no studies in Asian populations. In longitudinal analyses, we assessed the directionality of the associations between maternal feeding practices and body mass index (BMI) in preschoolers. Participants were 428 mother child dyads from the GUSTO (Growing Up in Singapore Toward healthy Outcomes) cohort. Read More

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https://www.frontiersin.org/article/10.3389/fnut.2019.00032/
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http://dx.doi.org/10.3389/fnut.2019.00032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454195PMC
April 2019
2 Reads