9,844 results match your criteria Asian Pacific journal of cancer prevention : APJCP[Journal]


Study of Dysphagia in Patients with Advanced Oropharyngeal Cancer Subjected to an Organ Preservation Protocol Based on Concomitant Radiotherapy and Chemotherapy

Asian Pac J Cancer Prev 2019 Mar 26;20(3):977-982. Epub 2019 Mar 26.

Head and Neck Surgery Department, Barretos Cancer Hospital, Barretos – SP, Brazil.

Introduction: Organ preservation protocol (based on chemo-radiotherapy) for oropharyngeal tumors include dysphagia as a possible sequel leading to function impairment and changes in patient’s quality of life. Objectives: The aim of this study is to assess dysphagia severity after treatment in advanced oropharyngeal cancer patients treated with concurrent chemo-radiation. Methods: This prospective cross-sectional study included 64 participants who had been disease free for at least six months after primary treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.977DOI Listing
March 2019
3 Reads

Incidence and Mortality of Cancers Related to Secondhand Smoking in Southeast Asia Countries

Asian Pac J Cancer Prev 2019 Mar 26;20(3):971-976. Epub 2019 Mar 26.

Graduate Program in Pharmacy Management, Faculty of Pharmacy, University Gadjah Mada, Indonesia.

Background: Secondhand smoke has been a big problem for human being worldwide as it is well-established risk factors for cancers. ASEAN (Association of Southeast Asian Nations) bear high burden of cancers since the high prevalence of secondhand smoke. The objective of this study is to estimate the burden of cancer attributable to secondhand smoking in ASEAN. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.971DOI Listing
March 2019
1 Read

Interaction of Safety Climate and Safety Culture: A Model for Cancer Treatment Centers

Asian Pac J Cancer Prev 2019 Mar 26;20(3):961-969. Epub 2019 Mar 26.

Health Research Center, Lifestyle Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Background: In health care institutions, safety culture is defined as the integrity of individual and group efforts to reduce the harms for the patients. This is possible through interactions, attitudes, and understanding of safety matters. On the other hand, one of the indicators of the safety culture is the safety climate. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.961DOI Listing

Using Citation Context to Improve the Retrieval of Research Article from Cancer Research Journals

Asian Pac J Cancer Prev 2019 Mar 26;20(3):951-960. Epub 2019 Mar 26.

School of Computer Science and Engineering (SCOPE),VIT, Vellore, India.

Objective: In recent years, citation analysis tools provide many devices for finding or computing the citation score or impact factor for journals. It is important for the researchers to identify good journals for collecting research ideas discussed. A journal with a good impact factor value is preferably referred to by many researchers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.951DOI Listing

Comparison of Plasma Zinc Levels Among HIV+ and HIV- Subjects Infected with Condyloma Acuminata

Asian Pac J Cancer Prev 2019 Mar 26;20(3):943-949. Epub 2019 Mar 26.

Department of Dermatology-Venereology, Faculty of Medicine, Udayana University-Sanglah General Hospital, Bali, Indonesia. Email:

Background: Condyloma acuminata is a type of human papilloma virus (HPV) infection in the anogenital area and often associated with immunosuppressive conditions, such as human immunodeficiency virus (HIV). Low plasma zinc levels could cause alteration of cellular immunity, leading to reduction of interleukin-2 (IL-2) and interferon-γ (IFN-γ), cytokines required for inhibition of HPV replication. Moreover, low plasma zinc levels could cause disruption of apoptotic regulation, results in the unimpeded proliferation of epithelial cells infected with HPV. Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_84935.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.3.943DOI Listing
March 2019
2 Reads

Association of Interleukin-10 Genotypes and Oral Cancer Susceptibility in Selected Malaysian Population: A Case- Control Study

Asian Pac J Cancer Prev 2019 Mar 26;20(3):935-941. Epub 2019 Mar 26.

Department of Oral Maxillo-Facial Pathology and Microbiology, Faculty of Dentistry, MAHSA University, Kuala Lumpur, Malaysia. Email:

Background: Interleukin-10 (IL10) genotypes have been closely correlated to the susceptibility for oral squamous cell carcinoma. More than half of oral cancers in the world occur in Asia with estimated 168,850 new cases were diagnosed in this geographical region alone. Considering the rising numbers of oral cancer cases in Malaysia, association of IL10 A1082G gene polymorphism was correlated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.935DOI Listing

A Proposal of a Clinically Based Classification for Idiopathic Granulomatous Mastitis

Asian Pac J Cancer Prev 2019 Mar 26;20(3):929-934. Epub 2019 Mar 26.

Department of General Surgery and Urology, Faculty of Medicine, Jordan University of Science and Technology, Jordan. Email:

Objectives: There is no consensus regarding the surgical or immunosuppressive treatment of idiopathic granulomatous mastitis (IGM). This study aimed to introduce a clinical classification system for IGM that might facilitate its treatment and predict recurrence. Methods: We analyzed the management of 68 patients with IGM at (Princess Basma Teaching Hospital and King Abdulla University Hospital (1994-2016) to find out if distinct patterns of presentation exist according to the following parameters: presence of a painful or painless breast mass, local inflammation, abscess formation, communication to the skin, and extra-mammary manifestation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.929DOI Listing
March 2019
1 Read
1.500 Impact Factor

OGG1 rs1052133 Polymorphism and Genetic Susceptibility to Chronic Myelogenous Leukaemia

Asian Pac J Cancer Prev 2019 Mar 26;20(3):925-928. Epub 2019 Mar 26.

Department of Clinical laboratory Science, College of Applied Medical Science, Imam Abdulrahman, Bin Faisal University, Saudi Arabia. Email:

Background: In some cancer cells, the OGG1 gene is somatically mutated and highly populated. This study was conducted to examine whether OGG1 rs1052133 polymorphism is associated with the genetic background of chronic myelogenous leukaemia (CML) in Sudan. Methods: A total of 332 CML patients and 70 healthy controls were included in this study. Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_84286.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.3.925DOI Listing
March 2019
3 Reads

Diagnostic Accuracy of Conventional Cell Blocks Along with p16INK4 and Ki67 Biomarkers as Triage Tests in Resource-poor Organized Cervical Cancer Screening Programs

Asian Pac J Cancer Prev 2019 Mar 26;20(3):917-923. Epub 2019 Mar 26.

OB/GYN, JNIMS Jawaharlal Nehru Institute of Medical Sciences. India.

Background: Liquid based cytology with dual biomarkers has improved sensitivity and specificity in detecting high grade cervical intraepithelial neoplasia (CIN). In low resource settings, especially in organized camps, LBC is costly and immunohistochemistry on conventional pap smears is difficult to standardize with consumption of lots of reagents. In present study, to improve the accuracy of conventional pap smears and reduce the cost of biomarker testing, we evaluated conventional cell blocks (CCBs) preparations with biomarkers to detect high-grade CIN in resource-poor organized screening programs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.917DOI Listing
March 2019
1 Read

Effects of Omega-3 Supplementation on Ki-67 and VEGF Expression Levels and Clinical Outcomes of Locally Advanced Breast Cancer Patients Treated with Neoadjuvant CAF Chemotherapy: A Randomized Controlled Trial Report

Asian Pac J Cancer Prev 2019 Mar 26;20(3):911-916. Epub 2019 Mar 26.

Division of Surgical Oncology, Department of Surgery, Dr. Sardjito Hospital, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia. Email:

Background: Omega-3 is a polyunsaturated fatty acid with an ability to regulate cell proliferation and apoptosis through interaction with inflammatory mediators. The potential additional beneficial effects of Omega-3 on chemotherapy patients with breast cancer is not yet completely revealed. Methods: A double-blind randomized control trial (RCT) involving a total of 48 locally advanced breast cancer patients was conducted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.911DOI Listing
March 2019
1 Read
1.500 Impact Factor

A Cross Sectional Study on Knowledge, Beliefs and Psychosocial Predictors of Shisha Smoking among University Students in Sharjah, United Arab Emirates

Asian Pac J Cancer Prev 2019 Mar 26;20(3):903-909. Epub 2019 Mar 26.

Department of Family and Community Medicine and Behavioral Sciences, College of Medicine, University of Sharjah, United Arab Emirates. Email:

Background: Smoking is now prohibited in all educational institutions and other public places in the United Arab Emirates (UAE), but shisha smoking is considered as one of the major problems among the students population. This study aimed to identify the (a) prevalence of ever shisha, current shisha and shisha dependency smokers among university students in the University of Sharjah (UOS), (b) knowledge and belief differences among ever shisha, current shisha as well as shisha dependency smoking students, (c) relationship between precipitating factors and shisha dependency and (d) precipitating factors (stimulation, handling, pleasure, tension reduction, addiction (dependency), automatism (habit) and social interaction, parents smoking behavior, knowledge and beliefs about smoking predict shisha dependency among students in UOS. Materials and Methods: In this cross sectional study, 633 students participated from UOS, UAE. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.903DOI Listing
March 2019
1 Read

The Anti-Proliferative and Pro-Apoptotic Properties of Ethanol Plectranthus amboinicus (Lour.) Spreng. Leaves Ethanolic Extract Nanoparticles on T47D Cell Lines

Asian Pac J Cancer Prev 2019 Mar 26;20(3):897-901. Epub 2019 Mar 26.

Department of Pharmaceutical Technology, Faculty of Pharmacy, University Sumatera Utara, Indonesia.

Objectives: Plectranthus amboinicus (Lour.) Spreng. is a plant which has the potential as an anti-cancer agent. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.897DOI Listing
March 2019
2 Reads

Prognostic Significance of High Androgen Receptor Expression in Prostatic Acinar Adenocarcinoma

Asian Pac J Cancer Prev 2019 Mar 26;20(3):893-896. Epub 2019 Mar 26.

Department of Histopathology, Liaquat National Hospital and Medical College, Karachi, Pakistan. Email:

Background: Quantitative immunohistochemical expression of Androgen receptor (AR) has not been evaluated as a prognostic biomarker of prostate cancer in our population, therefore in the current study we aimed to evaluate the association of AR expression in prostatic acinar adenocarcinoma with various prognostic parameters like tumor quantification, Gleason score, WHO grade group and perineural invasion. Methods: Total 121 cases of biopsy proven prostatic acinar adenocarcinoma were selected from records of pathology department archives from January 2013 till December 2017. Hematoxylin and eosin stained slides and paraffin blocks were retrieved and new sections were cut where necessary. Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_82668.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.3.893DOI Listing
March 2019
4 Reads
1.500 Impact Factor

Total Body Irradiation and Risk of Diabetes Mellitus; A Meta-Analysis

Asian Pac J Cancer Prev 2019 Mar 26;20(3):885-891. Epub 2019 Mar 26.

University of Hawaii, internal Medicine Residency Program, Honolulu, HI, USA. Email:

Objective: Hematopoietic stem cell transplant (HSCT) has recently emerged as a cure for previously “incurable” diseases and is being explored and attempted in many other fields including congenital and acquired non-malignant diseases. However, the long-term side effect associated with HSCT especially Total Body Irradiation (TBI) is still understudied. Therefore, we attempted to establish association between TBI and risk of developing Diabetes Mellitus (DM) or impaired glucose metabolism (IGM). Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_82664.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.3.885DOI Listing
March 2019
5 Reads

Awareness Level about Breast Cancer Risk Factors, Barriers, Attitude and Breast Cancer Screening among Indonesian Women

Asian Pac J Cancer Prev 2019 Mar 26;20(3):877-884. Epub 2019 Mar 26.

Biostatistics Center of Excellence, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Globally, breast cancer is the second most common cancer in women and is a leading cause of mortality in Indonesia. Raising awareness of breast cancer is particularly important to help at risk women seek medical treatment for this disease. This study aimed to comprehensively investigate the Indonesian women’s level of knowledge about breast cancer risk factors, barriers, attitude and breast cancer screening. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.877DOI Listing
March 2019
1 Read

Post Marketing Surveillance Study of 2nd Dose Quadrivalent Human Papilloma Virus Vaccine in Elementary School Children in Jakarta, Indonesia: Safety Result and Implementation of School-Based HPV Immunization Program

Asian Pac J Cancer Prev 2019 Mar 26;20(3):869-875. Epub 2019 Mar 26.

Indonesia Ministry of Health, Immunization Sub-Directorate at Directorate of Surveillance, Immunization and Health Quarantine, Jakarta, Indonesia.

Objective: Quadrivalent human papillomavirus (QHPV) vaccine has been advised for routine vaccination of pre-adolescent girls globally, and a two-dose QHPV vaccination schedule has been introduced in Indonesia to vaccinate 5th and 6th grade elementary school female students. This post-marketing surveillance study evaluated the possible adverse events following immunization with the two-dose QHPV vaccine in Indonesia. Methods: Girls studying in grade 6 of five designated elementary schools in Jakarta, receiving their 2nd dose of QHPV vaccine and provided informed consent (represented by their parents), were included in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.869DOI Listing
March 2019
1 Read

Pretreatment Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) as a Predictive Value of Hematological Markers in Cervical Cancer

Asian Pac J Cancer Prev 2019 Mar 26;20(3):863-868. Epub 2019 Mar 26.

International Program of Medicine, Taipei Medical University, Taipei, Taiwan.

Background: Inflammation represents a pivotal role in the progression of cervical cancer. The hematological markers of inflammation in complete blood count (CBC) panel are potentially useful in determining the prognosis of the disease. Objective: The aim of the study was to investigate whether the pretreatment neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) could be used as in predicting the stage of cervical cancer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.863DOI Listing
March 2019
1 Read

The Prefectural Participation Rates of Lung Cancer Screening Had a Negative Correlation with the Lung Cancer Mortality Rates

Asian Pac J Cancer Prev 2019 Mar 26;20(3):855-861. Epub 2019 Mar 26.

Division of Chest Surgery, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.

Background: The participation rate is one of the most important indexes in the cancer screening. Historically in Japan, each local government has developed their own equations to calculate the subjects for population-based screening, which were different from each other, and therefore the participation rates of screening were not comparable. Recently, local governments were ordered to use the standardized equation in reporting data, which made it possible to compare the participation rates of cancer screening nationwide for the first time. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.855DOI Listing

Predictors of Absent High-grade Cervical Intraepithelial Neoplasia (CIN) in Loop Electrosurgical Excision Procedure Specimens of Patients with Colposcopic Directed Biopsy-Confirmed High-Grade CIN

Asian Pac J Cancer Prev 2019 Mar 26;20(3):849-854. Epub 2019 Mar 26.

Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University Hospital, Pathumthani, Thailand. Email:

Objective: To determine predictors of having cervical intraepithelial neoplasia (CIN) 1 or less in loop electrosurgical excision procedure (LEEP) specimens of patients with colposcopic directed biopsy-confirmed CIN 2-3. Methods: Two hundred and eighty patients with colposcopic directed biopsy-confirmed CIN 2-3 who subsequently underwent LEEP were enrolled in the retrospective study. Related clinical data were collected to determine the predictors of CIN 1 or less in LEEP specimens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.849DOI Listing
March 2019
2 Reads

Association of Protein Expression and Methylation of DAPK1 with Clinicopathological Features in Invasive Ductal Carcinoma Patients from Kashmir

Asian Pac J Cancer Prev 2019 Mar 26;20(3):839-848. Epub 2019 Mar 26.

Department of Biotechnology, School of Life Sciences, Central University of Kashmir, Srinagar, J and K, India. Email:

Aims: Death-associated protein kinase-1 (DAPK1) is a pro-apoptotic Ser/Thr kinase that participates in cell apoptosis and tumor suppression. DAPK1 is frequently lost in many different tumor types including breast cancer. The aim of this study was to evaluate the promoter methylation status of DAPK1 and a possible correlation with the expression of DAPK1 and standard clinicopathological features in invasive ductal breast carcinoma patients (IDC). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.839DOI Listing
March 2019
1 Read

Knowledge and Practices of Colorectal Cancer Early Detection Examinations in Jordan: A Cross Sectional Study

Asian Pac J Cancer Prev 2019 Mar 26;20(3):831-838. Epub 2019 Mar 26.

Faculty of Medicine, Lund University, Lund, Sweden. Email:

Background: Globally, colorectal cancer (CRC) is ranked the third most common cancer among men and the second in women. The American Cancer Society recommends that starting from the age 50 years, both men and women should be screened for polyps and for early detection of CRC. In Jordan, CRC is the most common cancer among males and the second most common cancer among females. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.831DOI Listing

Association of EGFR 1 Gene Alteration and their Association with Lung Adenocarcinoma Patients

Asian Pac J Cancer Prev 2019 03 26;20(3):825-830. Epub 2019 Mar 26.

Department of Biochemistry, Maulana Azad Medical College and Associated Hospitals, New Delhi, India. Email:

Background: The epidermal growth factor receptor 1 (EGFR1) plays a significant role in cell proliferation and development. Its regulation in humans is very critical and incompletely understood in Non small cell lung cancer (NSCLC). Methods: 100 newly diagnosed NSCLC (lung adenocarcinoma) patients and 100 healthy controls were included and allele specific (AS) polymerase chain reaction (PCR) was used to genotype and expression was analyzed by quantitative real time PCR. Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_82575.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.3.825DOI Listing
March 2019
13 Reads
1.500 Impact Factor

Autologous Platelet-Released Growth Factor and Sexual Dysfunction Amendment: A Pilot Clinical Trial of Successful Improvement Sexual Dysfunction after Pelvic Irradiation

Asian Pac J Cancer Prev 2019 03 26;20(3):817-823. Epub 2019 Mar 26.

Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Sexual dysfunction (SDF) is a common sequel to cancer treatment which affects the quality of life in women treated with pelvic radiotherapy. The aim of this study was to evaluate the safety, symptom resolution and objective improvement the injection of autologous platelet released growth factor (APRGF) for treatment of SDF in cited patients. This prospective pilot study enrolled 10 cancer-free patients with SDF who underwent pelvic radiotherapy at least 5 years ago, randomly. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.817DOI Listing
March 2019
1 Read
1.500 Impact Factor

Relation between Tetraspanin- Associated and Tetraspanin- Non- Associated Exosomal Proteases and Metabolic Syndrome in Colorectal Cancer Patients

Asian Pac J Cancer Prev 2019 Mar 26;20(3):809-815. Epub 2019 Mar 26.

Cancer Research Institute, Тomsk National Research Medical Center, Russian Academy of Science, Tomsk, Russia. Email:

Purpose: Exosomal proteases are important in regulation of molecular signaling from growth factor receptors and adhesion molecules and also the regulation of cell motility and protein folding. The aim of this study was to evaluate the level of ADAM10, ADAM17 and 20S proteasomes in exosomes isolated from colorectal cancer patients (CRCPs) in relation with clinical and histopathological parameters. Methods: Blood plasma exosomes of 60 CRCPs at stage T2-4N0-2M0-1 and 10 control subjects (CSs) with colorectal polyps were isolated using ultrafiltration in combination with ultracentrifugation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.809DOI Listing

The Nudix Hydrolase 15 (NUDT15) Gene Variants among Jordanian Arab Population

Asian Pac J Cancer Prev 2019 Mar 26;20(3):801-808. Epub 2019 Mar 26.

College of Pharmacy, AlZaytoonah University of Jordan, Amman, Jordan. Email:

Background: Nudix Hydrolase 15 gene (NUDT15) encodes nucleotide triphosphate diphosphatase which metabolizes the purine analog drugs, such as anticancer thiopurine and anti-gout allopurinol. Genetic variants on Nudix Hydrolase 15 gene (NUDT15) gene effects the drug’s hydrolyses and hence increases the susceptibility to drug-induced toxicity. The NUDT15 gene has been genotyped in various ethnic groups, however, it has not been genotyped among the Middle Eastern Arab Jordanian population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.801DOI Listing
March 2019
1 Read

Impact of Diarrhea after Drinking on Colorectal Tumor Risk: A Case Control Study

Asian Pac J Cancer Prev 2019 Mar 26;20(3):795-799. Epub 2019 Mar 26.

Department of Molecular Pathology, Osaka University Graduate School of Medicine and Health Science, Osaka, Japan.

Background: Recently, the number of colorectal cancer (CRC) cases in Japan has been increasing, and is strongly influenced by alcohol consumption. On the other hand, there are several reports suggesting a relationship between bowel movement (constipation and diarrhea) and CRC development. Moreover, it is generally known that diarrhea may occur after drinking. Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_84473.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.3.795DOI Listing
March 2019
3 Reads

Validation of the Accuracy of Self-Reported ABO Blood Types in the Japan Nurses’ Health Study

Asian Pac J Cancer Prev 2019 Mar 26;20(3):789-793. Epub 2019 Mar 26.

Department of Laboratory Sciences, Graduate School of Health Sciences, Gunma University, Maebashi, Japan. Email:

Background: The associations between ABO blood type and risk of diseases including cancer have been reported from epidemiological studies. Self-reporting is one of the most widely used methods of collecting the ABO blood type information. Verifying the accuracy of self-reporting is important to consider measurement errors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.789DOI Listing
March 2019
1 Read

Gleason Pattern 5 is a Possible Pathologic Predictor for Biochemical Recurrence after Laparoscopic Radical Prostatectomy

Asian Pac J Cancer Prev 2019 Mar 26;20(3):783-788. Epub 2019 Mar 26.

Department of Urology, Kitasato University Kitasato Institute Hospital, Tokyo, Japan. Email:

Objective: Several prognostic factors for biochemical recurrence after radical prostatectomy have been reported, including initial prostate-specific antigen level, Gleason score, positive surgical margin, and seminal vesicle invasion. Here we investigate whether Gleason pattern 5 is a predictor for biochemical recurrence. Methods: This retrospective study included 168 patients who underwent laparoscopic radical prostatectomy from 2006 to 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.783DOI Listing

Risk Factors of Gastric Cancer in High-Risk Region of China: A Population-Based Case-control Study

Asian Pac J Cancer Prev 2019 Mar 26;20(3):775-781. Epub 2019 Mar 26.

Fujian Xianyou Hospital, Putian, China.

Background: The reason for the high incidence of gastric cancer (GC) in Xianyou County of China was largely unknown. We aimed to explore the potential sociodemographic risk factors and their associations to GC. Methods: A population-based case-control study was conducted during March 2013 and April 2016 in Xianyou County. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.775DOI Listing

Changed Body Image as Perceived by Jordanian Women Undergoing Breast Cancer Treatment

Asian Pac J Cancer Prev 2019 Mar 26;20(3):767-773. Epub 2019 Mar 26.

Faculty of Nursing, Zarqa University, Jordan. Email:

Background: Breast cancer is the most common cancer affecting women worldwide. The purpose of this study was to generate an understanding of women’s perceptions of changes to their body image due to breast cancer treatment. Method: A phenomenological qualitative approach was taken and semi-structured interviews conducted with 20 women who underwent breast cancer treatment at a public hospital in Jordan. Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_82574.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.3.767DOI Listing
March 2019
3 Reads

Evaluation of Ultra-Microscopic Changes and Proliferation of Apoptotic Glioblastoma Multiforme Cells Induced by Velogenic Strain of Newcastle Disease Virus AF2240

Asian Pac J Cancer Prev 2019 Mar 26;20(3):757-765. Epub 2019 Mar 26.

Faculty of Agriculture and Biotechnology, University Sultan Zainalb Abidin, Malaysia.

Aim: Newcastle disease virus (NDV) is a member of genus Avulavirus within the family Paramyxoviridae. Interest of using NDV as an anticancer agent has arisen from its ability to kill tumor cells with limited toxicity to normal cells. Methods: In this investigation, the proliferation of brain tumor cell line, glioblastoma multiform (DBTRG. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.757DOI Listing

Serum Levels of APRIL Increase in Patients with Glioma, Meningioma and Schwannoma

Asian Pac J Cancer Prev 2019 Mar 26;20(3):751-756. Epub 2019 Mar 26.

Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Email:

Objective: Brain tumors are of high mortality and morbidity for which there is still no cure. The TNF family cytokine, A Proliferation Inducing Ligand (APRIL), is shown to help proliferation and development of tumor cells. We assessed serum levels of APRIL in patients with glioma, meningioma and schwannoma in comparison to healthy individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.751DOI Listing

The Role of Muscle Relaxants – Spasmolytic (Thiocochlicoside) in Postoperative Pain Management after Mastectomy and Breast Reconstruction

Asian Pac J Cancer Prev 2019 Mar 26;20(3):743-749. Epub 2019 Mar 26.

Department of Nursing, Technological Educational Institute of Athens, Athens, Greece.

Purpose: Post-operative pain after breast cancer surgery is a major problem and women undergoing mastectomy and breast reconstruction experience post-operative pain syndromes in approximately one-half of all cases. Patients who have undergone breast reconstruction after mastectomy can suffer from acute postoperative pain with moderate or strong tension. In some cases, chronic neuropathic pain syndromes may occur after surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.743DOI Listing
March 2019
1.500 Impact Factor

Accounting for Immigrant Status when Calculating Cancer Incidence Rates for Bangkok

Asian Pac J Cancer Prev 2019 03 26;20(3):737-741. Epub 2019 Mar 26.

Health System Development National Cancer Institute Bangkok, Thailand. Email:

Objective: Cancer-registry data are crucial for definingcancer incidence rates for use in setting service priorities and monitoringservice effects. This applies in Thailand where cancer is the leading cause of death and service needs are high. The Bangkok Cancer Registry (population-based) was established in 1990to determine cancer incidence rates for Bangkok. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.737DOI Listing

Prognostic and Predictive Role of Angiogenic Markers in Non- Small Cell Lung Cancer

Asian Pac J Cancer Prev 2019 Mar 26;20(3):733-736. Epub 2019 Mar 26.

Department of Medical Oncology, Istanbul University, Istanbul, Turkey.

Objective: Despite the existence of detailed consensus guidelines, challenges remain regarding the role angiogenetic factors on non-small cell lung cancer (NSCLC). This study was conducted to determine the role of the vascular endothelial growth factor (VEGF), interleukin-8 (IL-8) and angiopoietin2 (Ang2) in patients with NSCLC. Methods: This study included 64 consecutive patients with non-small cell lung cancer, who admitted to clinic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.733DOI Listing
March 2019
1 Read

Breast Cancer Diagnostic Efficacy in a Developing South-East Asian Country

Asian Pac J Cancer Prev 2019 Mar 26;20(3):727-731. Epub 2019 Mar 26.

St Matthews Catholic School, Mudgee, New South Wales, Australia. Email:

Background: Breast cancer, is increasing in prevalence amongst South East (SE) Asian women, highlighting the need for high quality, early diagnoses. This study investigated radiologists’ detection efficacy in a developing (DC) and developed (DDC) SE Asian country, as compared to Australian radiologists. Methods: Using a test-set of 60 mammographic cases, 20 containing cancer, JAFROC figures of merit (FOM) and ROC area under the curves (AUC) were calculated as well as location sensitivity, sensitivity and specificity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.727DOI Listing
March 2019
1 Read

Evaluation of Cisplatin Efficacy on HepG2 and E. coli Cells under Acidic Conditions

Asian Pac J Cancer Prev 2019 03 26;20(3):723-726. Epub 2019 Mar 26.

Food and Drug Laboratory Research Center and Food and Drug Reference Control Laboratories Center, Food and Drug Administration of Iran, MOH and ME, Tehran, Iran. Email:

Background: Cisplatin (Cispt) is a common anticancer drug for the treatment of several malignancies, including hepatocarcinoma. However, this drug suffers from instability in aqueous solutions. The study aimed to evaluate cisplatin efficacy on HepG2 and E. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.723DOI Listing

A Self-Help Guided Psychoeducational Intervention for Indonesian Women with Breast Cancer Symptoms: Development and Pilot Feasibility Study

Asian Pac J Cancer Prev 2019 Mar 26;20(3):711-722. Epub 2019 Mar 26.

Department of Clinical, Neuro-and Developmental Psychology, Faculty of Behavioural and Movement Sciences, VU University, Amsterdam, Netherlands.

Background: Delay in the diagnosis of breast cancer (BC) may lead to an advanced stage of the disease and a poor prognosis. A psychoeducational intervention can be crucial in helping women with BC symptoms complete the examination procedures and reduce diagnosis delay of BC. Objective: To develop a psychoeducational intervention to reduce the delay of BC diagnosis among Indonesian women with BC symptoms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.711DOI Listing

Hypoxia-Inducible Factor1-Α (HIF1α) and Vascular Endothelial Growth Factor-A (VEGF-A) Expression in De Novo AML Patients

Asian Pac J Cancer Prev 2019 03 26;20(3):705-710. Epub 2019 Mar 26.

HSCT Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Email:

Background: Bone marrow hypoxia can promote leukemia progression in human cases of acute myeloid leukemia (AML). In addition, low oxygen tension is able to regulate the expression of different genes involved in malignancy. In this study, we hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF-A) genes were assessed as principal regulators of hypoxia in do novo AML patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.705DOI Listing
March 2019
1 Read
1.500 Impact Factor

Relationship of Health Locus of Control with Breast Cancer Screening Belief of Iranian Women

Asian Pac J Cancer Prev 2019 03 26;20(3):699-703. Epub 2019 Mar 26.

Behavioral Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Email:

Promoting breast cancer screening (BCS) behavior of women can lead to a reduction in mortality. The health locus of control affects cancer screening behavior of women; however, there is not sufficient evidence regaring this issue in Iran. The overall goal of our study is to determine the relationship of the health locus of control with the breast cancer screening belief of Iranian Women. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.699DOI Listing

Factors Associated with the Occurrence of Thyroid Nodules in Severely Obese Patients: A Case-Control Study

Asian Pac J Cancer Prev 2019 Mar 26;20(3):693-697. Epub 2019 Mar 26.

Programa de Pós-Graduacão em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Brazil.

Background: The association of obesity with the occurrence of thyroid nodules and thyroid cancer has been demonstrated. However, there is limited knowledge on the risk factors of thyroid nodules in in severely obese patients. The aim was to evaluate the occurrence of thyroid nodules in severely obese and nonobese patients and determine the factors associated considering sociodemographic, lifestyle, and biochemical variables. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.693DOI Listing
March 2019
1 Read

Frequency of Epstein–Barr Virus DNA in Formalin-Fixed Paraffin-Embedded Tissue of Patients with Ductal Breast Carcinoma

Asian Pac J Cancer Prev 2019 Mar 26;20(3):687-692. Epub 2019 Mar 26.

Biostatistic Department, School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Ductal carcinoma is one of the most common breast cancer (BrC) among the women in the world. Several factors may involve in establishment of breast cancer. The role of viral infections have been investigated in BrC, Among them the association of Epstein Barr virus have been reported in the patients with breast cancer type ductal carcinoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.687DOI Listing

Histopathology of Women with “Atypical Squamous Cells Cannot Exclude High-Grade Squamous Intraepithelial Lesion” (ASC-H) Smears

Asian Pac J Cancer Prev 2019 Mar 26;20(3):683-686. Epub 2019 Mar 26.

Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Objectives: To evaluate prevalence of underlying significant pathologies among women with cervical smears rated as ‘atypical squamous cells cannot exclude high grade squamous intraepithelial lesion (ASC-H)’, as well as associated risk factors. Methods: Medical records were reviewed of all consecutive women with ASC-H smears who had undergone colposcopy at Srinagarind Hospital from January 2008 to July 2016. Significant pathology results included cervical intraepithelial neoplasia (CIN) 2-3, adenocarcinoma in situ (AIS), endometrial hyperplasia, and cancer of any original site. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.683DOI Listing
March 2019
1 Read

Association of GSTM1, GSTT1, GSTM3, and GSTP1 Genes Polymorphisms with Susceptibility to Osteosarcoma: a Case- Control Study and Meta-Analysis

Asian Pac J Cancer Prev 2019 Mar 26;20(3):675-682. Epub 2019 Mar 26.

Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Background: Some studies have investigated the association of GSTM1, GSTT1, GSTM3, and GSTP1 polymorphisms with susceptibility to osteosarcoma; however, these studies results are inconsistent and inconclusive. In order to drive a more precise estimation, the present case-control study and meta-analysis was performed to investigate association of GSTM1, GSTT1, GSTM3, and GSTP1 polymorphisms with osteosarcoma. Methods: Eligible articles were identified by a search of several electronic databases for the period up to May 5, 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.675DOI Listing
March 2019
1 Read
1.500 Impact Factor

Biological and Clinical Relevance of Long Non-Coding RNA PCAT-1 in Cancer, A Systematic Review and Meta-Analysis

Asian Pac J Cancer Prev 2019 Mar 26;20(3):667-674. Epub 2019 Mar 26.

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Long non-coding RNA (lncRNA) prostate cancer associated transcript 1 (PCAT-1) has been identified as a potential biomarker for the diagnosis and prognosis of various cancers. We performed this systematic review and meta-analysis to evaluate the role of dysregulation as well as the biological and clinical significance of lnc-PCAT-1 for predicting the malignancy status in several cancers. Two independent reviewers conducted an extensive search in electronic databases of Medline, Embase, Scopus, Web of Science and PubMed until the December of 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.667DOI Listing

Prostatic Adenocarcinoma: A Grading from Gleason to the New Grade-Group System: A Historical and Critical Review

Asian Pac J Cancer Prev 2019 Mar 26;20(3):661-666. Epub 2019 Mar 26.

Department of pathology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia. Email:

The introduction of the Gleason grading system revolutionised prognostic parameters and determination of patient treatment regiments for prostatic adenocarcinomas, and has become synonymous with prostate cancer, almost universally applied in clinical settings to predict radical prostatectomy specimen findings, potential biochemical failure, local recurrences, lymph nodes or distant metastases in patients not receiving any treatment as well as those receiving treatment including radiation therapy, surgical treatment such as radical prostatectomy and other therapies etc,. However, characterisation and classification of prostate cancer is very different compared to 40-50 years ago when Gleason scores were first introduced. Despite this radical shift in classification, the Gleason system has remained one of the most important prognostic factors in prostate cancer, only possible as a result of timely and appropriate modifications to this characterisation system made in 2005 and 2014. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.3.661DOI Listing
March 2019
2 Reads

Prevalence of Cervical Dysplasia in HIV-Positive and HIV-Negative Women at the Sihanouk Hospital Center of HOPE, Phnom Penh , Cambodia

Asian Pac J Cancer Prev 2019 Feb 28;20(2):653-659. Epub 2019 Feb 28.

Sihanouk Hospital Center of HOPE, Cambodia. Email:

Introduction: There is a high burden of cervical cancer in Cambodia, yet published data on the prevalence of cervical dysplasia and the risk factors contributing to the development of pre-cancerous lesions in Cambodian women is very limited. In addition, as it is well known that HIV positivity increases cervical cancer risk, it is important to quantify the prevalence of cervical dysplasia and carcinoma among Cambodian women living with HIV disease. Methods: A cross-sectional study was conducted with a sample of 499 HIV+ and 501 HIV- Cambodian women at the Sihanouk Hospital Center of HOPE. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.2.653DOI Listing
February 2019
2 Reads

Questionnaire Validation of Colorectal Cancer Literacy Scale among Thai People in Northeastern Thailand

Asian Pac J Cancer Prev 2019 Feb 26;20(2):645-651. Epub 2019 Feb 26.

Doctor of Public Health Program, Faculty of Public Health, Khon Kaen University, Thailand.

Background: Colorectal cancer is an important public health problem worldwide. Although progress in screening and treatment has considerably improved the prognosis in the developed world, in developing countries colorectal cancer mortality rate remains relatively high. Colorectal cancer screening literacy is an important initial step in overcoming this problem. Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_82383.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.2.645DOI Listing
February 2019
8 Reads

Antioxidant and Cytotoxicity Activities of Karamunting (Melastoma malabathricum L.) Fruit Ethanolic Extract and Quercetin

Asian Pac J Cancer Prev 2019 Feb 26;20(2):639-643. Epub 2019 Feb 26.

Department of Pharmacology and Therapeutics, Faculty of Medicine, Lambung Mangkurat University, South Kalimantan, Indonesia. Email:

Melastoma malabathricum L. is a type of plant naturally grows in Kalimantan that has medicinal properties. Ethanolic extract of M. Read More

View Article

Download full-text PDF

Source
http://journal.waocp.org/article_82548.html
Publisher Site
http://dx.doi.org/10.31557/APJCP.2019.20.2.639DOI Listing
February 2019
4 Reads

Domain-Based Analysis of Colon Polyp in CT Colonography Using Image-Processing Techniques

Asian Pac J Cancer Prev 2019 Feb 26;20(2):629-637. Epub 2019 Feb 26.

Department of Computer Science and Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India. Email:

Background: The purpose of the research was to improve the polyp detection accuracy in CT Colonography (CTC) through effective colon segmentation, removal of tagged fecal matter through Electronic Cleansing (EC), and measuring the smaller polyps. Methods: An improved method of boundary-based semi-automatic colon segmentation with the knowledge of colon distension, an adaptive multistep method for the virtual cleansing of segmented colon based on the knowledge of Hounsfield Units, and an automated method of smaller polyp measurement using skeletonization technique have been implemented. Results: The techniques were evaluated on 40 CTC dataset. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2019.20.2.629DOI Listing
February 2019
3 Reads