1,341 results match your criteria Asian Pacific journal of allergy and immunology[Journal]


A study of factors related to asthma exacerbation using a questionnaire survey in Niigata Prefecture, Japan.

Asian Pac J Allergy Immunol 2019 Mar 24. Epub 2019 Mar 24.

Department of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata City, Niigata, Japan.

Background: As indices of asthma control, exacerbations are equally important with symptoms and respiratory function. Thus, it is critical to recognize the risk factors of exacerbation.

Objective: We conducted a questionnaire survey of asthma patients in Niigata Prefecture to clarify the factors involved in asthma exacerbation. Read More

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http://dx.doi.org/10.12932/AP-080918-0404DOI Listing
March 2019
1 Read

Down-regulation of miR-155 after treatment with narrow-band UVB and methotrexate associates with apoptosis of keratinocytes in psoriasis.

Asian Pac J Allergy Immunol 2019 Mar 24. Epub 2019 Mar 24.

Center of Excellence in Immunology and Immune Mediated Diseases, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

Background: Psoriasis is a chronic inflammatory skin disease arising from a complex interaction between genetics, epigenetics, the host's immune system and the environment. Recent accumulated data revealed the dysregulation of various microRNAs (miRNAs) in several diseases including psoriasis.

Objective: We explored the functional role and regulation of hsa-miR-155-5p (miR-155) in an immortalized keratinocyte cell line (HaCaT), in relation to the pathogenesis and treatment of psoriasis. Read More

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http://dx.doi.org/10.12932/AP-031218-0451DOI Listing

Prevalence of local allergic rhinitis to Dermatophagoides pteronyssinus in chronic rhinitis with negative skin prick test.

Asian Pac J Allergy Immunol 2019 Mar 24. Epub 2019 Mar 24.

Division of Rhinology & Allergy, Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Local allergic rhinitis (LAR) is a localized nasal allergic response in the absence of systemic atopy that is characterized by local production of specific immunoglobulin E (sIgE), and a positive response to NAPT (nasal allergen provocation test).

Objective: The objective of this study is to investigate the prevalence of LAR in adults with chronic rhinitis (CR) and negative skin prick test to Dermatophagoides pteronyssinus (Dp), and to assess the clinical characteristics of LAR, comparing to non-allergic rhinitis (NAR).

Methods: Patients with history of CR with negative skin prick test (SPT) to Dp were recruited during January 2015-April 2016. Read More

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http://dx.doi.org/10.12932/AP-170918-0408DOI Listing
March 2019
1 Read

Inhibitory effects of Aristotelia chilensis water extract on 2,4-Dinitrochlorobenzene induced atopic-like dermatitis in BALB/c Mice.

Asian Pac J Allergy Immunol 2019 Mar 24. Epub 2019 Mar 24.

Department of Public Health, College of Natural Science, Keimyung University, Daegu, 42601, Republic of Korea.

Background: Maqui berry (Aristotelia chilensis) has been reported to have anti-glycation, anti-inflammation, lipogenesis-inhibiting activities highly related to its anti-oxidation function, but practical efficacy studies on immunological mechanisms for atopic dermatitis, have not been reported yet.

Objective: This study investigated the immune regulation mechanism of Aristotelia chilensis water extract (ACWE) related to atopic-like dermatitis METHODS: Antioxidant and anti-inflammatory effects of ACWE was assayed. Atopy inhibitory effect was evaluated using in vitro cell study and in vivo 2,4-dinitrochlorobenzene (DNCB)-induced mouse atopic-like dermatitis model. Read More

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http://dx.doi.org/10.12932/AP-190418-0298DOI Listing

Risk factors for drug allergies in Chinese children.

Asian Pac J Allergy Immunol 2019 Mar 24. Epub 2019 Mar 24.

Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.

Background: Drug allergy, or drug hypersensitivity, is a potentially fatal disorder, and patients labeled with drug allergies have restricted access to first-line treatments. Full knowledge of the characteristics associated with drug allergies and severe reactions during allergy evaluation is beneficial for appropriate risk stratification.

Objective: We sought to determine whether certain clinical characteristics are associated with drug allergies in Chinese children. Read More

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http://dx.doi.org/10.12932/AP-191018-0417DOI Listing
March 2019
4 Reads

Clinical characteristics of eperisone-induced immediate-type hypersensitivity.

Asian Pac J Allergy Immunol 2019 Mar 24. Epub 2019 Mar 24.

Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background: Eperisone is a commonly prescribed oral muscle relaxant, but few studies have been conducted of eperisone-induced hypersensitivity reactions.

Objective: The purpose of this study was to investigate the clinical manifestations of eperisone-induced immediate-type hypersensitivity, and to evaluate the role of an intradermal test (IDT) in eperisone-induced anaphylaxis.

Methods: This study was based on a retrospective review of medical records from 23 patients diagnosed as eperisone-induced immediate-type hypersensitivity with certain or probable causality. Read More

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http://dx.doi.org/10.12932/AP-211018-0420DOI Listing
March 2019
1 Read

Rate of actual metal allergy prior to dental treatment in subjects complaining of possible metal allergy.

Asian Pac J Allergy Immunol 2019 Mar 24. Epub 2019 Mar 24.

Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Background: Dental treatment for patients with self-reported metal allergy or concern about the possibility of having such an allergy is often difficult; such patients often undergo dermatological consultations for metal patch test (PT).

Objective: This study compared PT results for metal allergens and the clinical relevance of this among patients visiting Fukuoka Dental College Hospital.

Methods: We performed PT with metal allergens on patients with oral mucosa- or skin-related symptoms, or those concerned about adverse events associated with upcoming dental treatment. Read More

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http://dx.doi.org/10.12932/AP-241018-0425DOI Listing

Synergistic activation of Src, ERK and STAT pathways in PBMCs for Staphylococcal enterotoxin A induced production of cytokines and chemokines.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allergy & Clinical Immunology, Sino-French Hoffmann Institute, Center for Immunology, Inflammation, & Immune-mediated disease, Guangzhou Medical University, Guangzhou 510260, China.

Background: Staphylococcal enterotoxin A (SEA) is a well-known superantigen and stimulates human peripheral blood mononuclear cells (PBMCs) involving in the pathogenesis of inflammatory disorders and cancer.

Objective: To better understand the biological activities of SEA and the possible intracellular mechanisms by which SEA plays its roles in conditions like staphylococcal inflammatory and/or autoimmune disorders and immunotherapy.

Methods: Recombinant SEA (rSEA) was expressed in a prokaryotic expression system and its effects on the cytokine and chemokine production was examined by Enzyme-linked Immunospot (ELISpot) Assay and ELISA analysis. Read More

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http://dx.doi.org/10.12932/AP-220818-0396DOI Listing
January 2019
1 Read

Anaphylaxis to Beluga caviar.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Allergy department, Metz Regional Hospital, 1 allée du Château, 57530 Ars-Laquenexy, France.

Fish roe is an extremely rare cause of anaphylaxis and although its consumption has increased in recent years. We described the case of a 59-year-old man, who experienced an anaphylactic reaction after consuming caviar. Skin prick-test were performed with Beluga caviar, salmon caviar, cod, salmon, hen egg yolk and egg white, ovalbumin, ovomucoid, shrimp and mold. Read More

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http://dx.doi.org/10.12932/AP-010918-0399DOI Listing
January 2019
2 Reads

The expression profile of Jagged1 and Delta-like 4 in hepatocellular carcinoma.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Notch signaling has been linked to many cancers. However, there is still limited information about the expression and role of the Notch ligand in hepatocellular carcinoma (HCC).

Objective: To investigate the expression of JAG1 and DLL4 in HCC tissues. Read More

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http://dx.doi.org/10.12932/AP-040818-0388DOI Listing
January 2019
1 Read

Circulating BAFF and CXCL10 levels predict response to pegylated interferon in patients with HBeAg-positive chronic hepatitis B.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Center of Excellence in Hepatitis and Liver Cancer, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Thailand.

Background: B-cell activating factor (BAFF), an essential cytokine for B lymphocytes activation, has been implicated in the pathogenesis of chronic viral hepatitis. However, the role of BAFF in patients with chronic hepatitis B (CHB) undergoing antiviral therapy is unknown.

Methods: Patients with HBeAg-positive CHB treated with 48-week pegylated interferon (PEG-IFN; n = 42), who had stored plasma samples during treatment were recruited. Read More

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http://dx.doi.org/10.12932/AP-050718-0365DOI Listing
January 2019
1 Read

Successful treatment of normocomplementemic urticarial vasculitis with omalizumab: A report of three cases and literature review.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Urticarial vasculitis (UV) is a rare form of cutaneous leukocytoclastic vasculitis with persistent urticarial lesions. UV may be severe and refractory to standard treatment including antihistamines, anti-inflammatories, antimalarials, corticosteroids and immunosuppressants. Omalizumab, an anti-IgE antibody, is approved for chronic spontaneous urticaria. Read More

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http://dx.doi.org/10.12932/AP-050918-0402DOI Listing
January 2019
10 Reads

Dengue vaccine: Global development update.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Chula Vaccine Research Center, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

The first licensed dengue vaccine, CYD-TDV (Dengvaxia®), has received regulatory approval in a number of countries. However, this vaccine has some limitations. Its efficacy against DENV2 was consistently lower than other serotypes. Read More

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http://dx.doi.org/10.12932/AP-100518-0309DOI Listing
January 2019

Practical considerations of nebulized corticosteroid in children with acute asthmatic exacerbation: A consensus.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Acute asthmatic exacerbation in children causes economic burdens both directly and indirectly. The GINA guideline does mention the use of inhaled or oral corticosteroids in the treatment of asthmatic exacerbation, it provides little practical guidance on the use of nebulized corticosteroid.

Objective: To review and recommend the practical considerations in the use of nebulized corticosteroid in children with acute asthmatic exacerbation. Read More

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http://dx.doi.org/10.12932/AP-170918-0407DOI Listing
January 2019
11 Reads

Intravenous aspirin challenge as a diagnosis of nonsteroidal anti-inflammatory drugs hypersensitivity.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are a major cause of drug-induced hypersensitivity, called "NSAID hypersensitivity". A confirmative diagnosis is necessary for ensuring drug safety and finding alternative drugs. No reliable test other than direct challenge is diagnostic. Read More

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http://dx.doi.org/10.12932/AP-151018-0416DOI Listing
January 2019

Real-world observational study of the evaluation of inhaler techniques in asthma patients.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Division of Pulmonary, Critical Care and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Background: Inhaler devices are a keystone in the management of asthma during the maintenance phase of treatment.

Objective: To evaluate techniques for using inhaler devices in asthma patients.

Methods: A prospective cross-sectional study was conducted to assess patient compliance with correct techniques for using inhaler devices across three regimens: pressurized metered-dose inhaler (pMDI), Accuhaler®, and Turbuhaler®. Read More

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http://dx.doi.org/10.12932/AP-210618-0348DOI Listing
January 2019
7 Reads
1.255 Impact Factor

Plasma B-cell activating factor levels and polymorphisms in hepatitis B-related hepatocellular carcinoma: Clinical correlation and prognosis.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Center of Excellence in Hepatitis and Liver Cancer, Faculty of Medicine, Chulalongkorn University, Thailand.

Background: B-cell activating factor (BAFF), an important cytokine for B lymphocyte activation, has been shown to be increased in chronic hepatitis B virus (HBV) infection.

Objectives: This study aimed at evaluating clinical correlation and prognostic role of plasma BAFF and related polymorphisms in patients with HBV-related hepatocellular carcinoma (HCC).

Methods: Plasma BAFF levels were measured from 100 healthy controls and 490 patients with chronic HBV infection (200 with HCC and 290 without HCC). Read More

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http://dx.doi.org/10.12932/AP-250718-0376DOI Listing
January 2019
8 Reads

Cut-off values for positive bronchodilator response in healthy Thai preschool children using forced oscillation technique.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Division of Clinical Epidemiology, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Forced oscillation technique (FOT) requires minimal patient cooperation and is particularly useful in young children. Bronchodilator test is a valuable tool for wheezy and asthmatic patients. The cut-off value for bronchodilator response by FOT in healthy Thai children has not been reported. Read More

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http://dx.doi.org/10.12932/AP-280718-0381DOI Listing
January 2019
1 Read

Oral tolerance:Recent advances on mechanisms and potential applications.

Asian Pac J Allergy Immunol 2018 Dec;36(4):207-216

Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Oral tolerance is a type of immune hypo-responsiveness induced by oral administration of food or harmless gastrointestinal antigens. It is evident that the induction of oral tolerance can protect our body from enteric problems, such as food allergies and colitis caused by autoimmunity. Here we review the immunological mechanisms of oral tolerance, the role of T cell cytokines in generating tolerance and the impact of Peyer's patches and mesenteric lymph nodes, and discuss the part played by commensal microflora in the regulation and maintenance of the intestinal barrier. Read More

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http://dx.doi.org/10.12932/AP0848DOI Listing
December 2018
1 Read

Polymorphisms in the interleukin 4 receptor and interleukin 13 genes in immediate allergic reactions to beta-lactam antibiotics: A case-control study.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke (QC), Canada.

Background: Immediate hypersensitivity reactions to beta-lactams are IgE-mediated and constitute the most common adverse reactions to antibiotics mediated by a specific immunologic mechanism.

Objective: We investigated the association between four functional polymorphisms of IL13 (R130Q variant) and IL4RA (I50V, S478P and Q551R variants) genes and susceptibility to immediate allergic reactions to beta-lactams in the Algerian population.

Methods: We determined these gene variants in 199 patients and 99 healthy controls from Algeria. Read More

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http://dx.doi.org/10.12932/AP-290318-0290DOI Listing
December 2018
6 Reads

A novel allergen-specific therapy with regulatory T cells induced by CD40-silenced dendritic cells.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Departments of Otorhinolaryngology, Nagoya City University.

Background: We previously reported that dendritic cells (DCs) transfected with CD40 siRNA and pulsed by ovalbumin (OVA) (CD40-silenced OVA DCs) inhibited allergic responses through facilitation of regulatory T cells (Tregs). However, to our knowledge, no prior study has examined allergen-specific therapy by administration of siRNA-induced Tregs for the control of allergy.

Objective: We aimed to investigate the effect of Tregs induced in vitro on allergic responses and symptoms in vivo. Read More

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http://dx.doi.org/10.12932/AP-240418-0302DOI Listing
December 2018
1 Read

Schnitzler's syndrome: A female elderly case presenting intractable non-pruritic febrile urticarial rush.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Graduate School of Medical Sciences, Department of Dermatology, Kyushu University, Fukuoka, Japan.

Schnitzler's syndrome is an acquired autoinflammatory disease characterized by chronic urticarial rash and monoclonal gammopathy (predominantly IgM type). A 75-year-old Japanese woman complained of high fever and non-pruritic urticarial rash appearing almost every day for 3 years. Her abnormal laboratory data included leukocytosis and neutrophilia with elevated erythrocyte sedimentation rate and C-reactive protein level. Read More

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http://dx.doi.org/10.12932/AP-150818-0394DOI Listing
December 2018
11 Reads

Prevalence and risk factors of allergic rhinitis in children in Bangkok area.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Allergic rhinitis (AR) is a disease with a high global disease burden and significant morbidity and expense. Risk factors are not well understood.

Objective: The objective of our project is to study the prevalence and risk factors of AR in children living in the Bangkok area. Read More

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http://dx.doi.org/10.12932/AP-120618-0337DOI Listing
December 2018
2 Reads

Prevalence of allergic rhinitis comorbidity with asthma and asthma with allergic rhinitis in China: A meta-analysis.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Department of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.

Background: Allergic rhinitis (AR) and asthma are the most common inflammatory diseases of the airways. The relationship between asthma and AR is widely and clinically recognised. The concept "one airway, one disease" has been gradually accepted. Read More

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http://dx.doi.org/10.12932/AP-120417-0072DOI Listing
December 2018
1 Read

Reference value of Forced Oscillation Technique for healthy preschool children.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Division of Pediatrics Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University.

Background: The reference values of Forced Oscillation Technique (FOT) parameters of the inspiratory and expiratory phase for preschool children have not yet been established.

Objective: To evaluate FOT measures in Thai healthy preschool children.

Methods: Preschool children, aged 3-6 years, were screened. Read More

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http://dx.doi.org/10.12932/AP-110618-0334DOI Listing
December 2018
4 Reads

Effects of self-prepared hypertonic nasal saline irrigation in allergic rhinitis: A randomized controlled trial.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Clinical Trials and Evidence-Based Syntheses Research Unit (CTEBs RU), Department of Clinical Pharmacy, Faculty of Pharmacy, Mahasarakham University, Khamriang, Kantarawichai, Maha Sarakham, Thailand.

Background: Nasal saline irrigation has been reported to be effective as an adjunctive therapy for allergic rhinitis (AR), but concerns about adverse events, supply problems, and high costs have limited its widespread clinical use. Aqueous 1.8% sodium chloride solution prepared by patients using drinking water (1. Read More

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http://dx.doi.org/10.12932/AP-090618-0331DOI Listing
December 2018
1 Read

Development of an immunomagnetic separation-ELISA for the detection of Burkholderia pseudomallei in blood samples.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Department of Microbiology.

Background: Septicemic melioidosis caused by Burkholderia pseudomallei is a serious cause of morbidity and mortality. An effective, rapid and simple diagnostic method is required for detection of B. pseudomallei infection. Read More

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http://dx.doi.org/10.12932/AP-080518-0307DOI Listing
December 2018

Unilateral generalized morphea: First case report in Taiwan.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Department of Allergy, Immunology and Rheumatology, Mackay Children's Hospital, Taipei, Taiwan.

Generalised morphea (GM) is a subtype of localised scleroderma that usually manifests with bilateral involvement. Unilateral generalised morphea (UGM) is a rare variant of GM. This is a case report of a Taiwanese girl with UGM over the left side of her body. Read More

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http://dx.doi.org/10.12932/AP-020818-0387DOI Listing
December 2018
1 Read

Medication used to control symptoms of chronic urticaria in children.

Asian Pac J Allergy Immunol 2018 Dec 9. Epub 2018 Dec 9.

Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: A number of guidelines for management of CU were established based on evidences in adults. In children, the response to CU treatment was not widely studied.

Objective: To investigate the medications used to control symptoms of CU in children and to identify factors associated with time to control CU. Read More

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http://dx.doi.org/10.12932/AP-010218-0247DOI Listing
December 2018
2 Reads

Disseminated cryptococcosis in two boys with novel mutation of CD40 Ligand-Associated X-linked hyper-IgM syndrome.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

X-linked hyper-IgM syndrome (XHIM) caused by CD40L mutations is a primary immunodeficiency condition that increases susceptibility to opportunistic infections. Disseminated cryptococcosis in XHIM is rarely reported in children. Here, we report two related boys who have a novel hemizygous frameshift c. Read More

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http://dx.doi.org/10.12932/AP-140218-0265DOI Listing
October 2018
1 Read

Accuracy of in-house alcohol-dissolved wheat extract for diagnosing IgE-mediated wheat allergy.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Samitivej Allergy Institute, Samitivej Thonburi Hospital, Thonburi, Bangkok, Thailand.

Background: The standard method for diagnosing immediate wheat allergy is oral food challenge test (OFC). However, OFC can provoke anaphylaxis during the challenge process. Skin prick test (SPT) using commercial wheat extract yielded unsatisfactory result for diagnosis of wheat allergy. Read More

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http://apjai-journal.org/wp-content/uploads/2018/10/AP-14021
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http://dx.doi.org/10.12932/AP-140218-0265DOI Listing
October 2018
10 Reads

Purpuric drug eruption without leukocytoclastic vasculitis associated with vancomycin.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Department of Pediatrics, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505, Japan.

Vancomycin (VCM) has been reported to elicit adverse cutaneous drug reactions. However, VCM-associated purpuric drug eruption has not been reported yet, except leukocytoclastic vasculitis. A 16-year-old Japanese girl was admitted with a respiratory infection. Read More

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http://apjai-journal.org/wp-content/uploads/2018/10/AP-21051
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http://dx.doi.org/10.12932/AP-210518-0319DOI Listing
October 2018
14 Reads
1.255 Impact Factor

Anaphylaxis: Ten-year retrospective study from a tertiary-care hospital in Northern Thailand.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Background: The study of anaphylaxis in different geographic areas raises the awareness to improve prevention and medical care.

Objective: To investigate the incidence, causes, characteristics, and management of anaphylaxis in Chiang Mai, Thailand METHODS: We performed a retrospective review, based on ICD-10 electronic medical records of patients who attended the Out-Patient and Emergency Departments at Chiang Mai University Hospital from January 2007 to December 2016.

Results: A total of 441 episodes of anaphylaxis in 433 patients were analyzed. Read More

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http://dx.doi.org/10.12932/AP-210318-0284DOI Listing
October 2018
2 Reads

WITHDRAWN:Comparison of immediate hypersensitivity reaction rate according to the type of radiocontrast media.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

The paper entitled "Comparison of immediate hypersensitivity reaction rate according to the type of radiocontrast media" by Hye Jung Park et al, which was published online on 15 October 2018, has been withdrawn at the authors' request. Read More

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http://apjai-journal.org/wp-content/uploads/2018/10/AP-19101
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http://dx.doi.org/10.12932/AP-191017-0182DOI Listing
October 2018
9 Reads

Prevalence and cluster effect of self-reported allergic reactions among insect consumers: An internet survey from Thailand.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Mahidol University International College, Mahidol University, Nakhon Pathom, Thailand.

Background: Entomophagy is a common practice in many parts of the world. Allergic symptoms after insect consumption have been reported in healthcare literature and in the news.

Objective: We evaluated prevalence and association of allergic history and self-reported allergic reactions after entomophagy. Read More

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http://dx.doi.org/10.12932/AP-220218-0271DOI Listing
October 2018
3 Reads

Prevalence and severity of asthma, rhinoconjunctivitis and eczema in children from the Bangkok area: The Global Asthma Network (GAN) Phase I.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: As noted in the reports of ISAAC phase I and III, allergic diseases are very common in Thailand, especially among younger children.

Objective: The objectives of this project are to study the prevalence and severity of the most common allergic diseases. i. Read More

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http://apjai-journal.org/wp-content/uploads/2018/10/AP-12061
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http://dx.doi.org/10.12932/AP-120618-0336DOI Listing
October 2018
13 Reads

Proteomic Identification of Allergenic Proteins of Morus alba L. Pollenexacerbation.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Department of Molecular Biology and Genetics, Faculty of Science, Istanbul University, Istanbul, Turkey.

Background: Tree pollens are well-known aeroallergens all over the world. Little is known about the allergenicity of Morus alba (white mulberry) pollen.

Objecive: We aimed to explore the potential allergens of this pollen and its clinical relevance in tree pollen allergic patients living in Istanbul, Turkey. Read More

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http://apjai-journal.org/wp-content/uploads/2018/10/AP-12041
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http://dx.doi.org/10.12932/AP-120418-0296DOI Listing
October 2018
15 Reads

Preventive and therapeutic effects of vitamin D in a mouse model of allergic asthma.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Department of Pediatrics, Inha University College of Medicine, Incheon, Korea.

Background: Vitamin D produces an anti-allergic effect that prevents inflammation due to asthma.

Objective: We investigated whether vitamin D has an anti-inflammatory effect on the sensitization and challenge stages of asthma development in a murine model.

Methods: Mice were divided into the following five groups according to ovalbumin (OVA) and vitamin D (VD) administration: control group, OVA group, preventive VD group (VD injection before OVA sensitization), inhibitory VD group (VD injection after OVA challenge), and dual VD groups (VD injection before OVA sensitization and after OVA challenge). Read More

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http://apjai-journal.org/wp-content/uploads/2018/10/AP-01021
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http://dx.doi.org/10.12932/AP-010218-0248DOI Listing
October 2018
15 Reads

CXCL12 G801A polymorphism is associated with significant liver fibrosis in HIV-infected Thais: a cross-sectional study.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Department of Medical Technology.

Background: Previous studies indicate high prevalence of liver diseases in HIV-infected patients, and their genetic risk factors are still unclear. The chemokine CXCL12 plays important roles in development of chronic liver injury and a single nucleotide polymorphism (SNP) G to A change at position 801 in CXCL12 gene has been demonstrated to affect CXCL12 production levels.

Objective: This study aimed to analyze the association of CXCL12 G801A SNP with liver complication in HIV-infected Thais. Read More

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http://dx.doi.org/10.12932/AP-160917-0162DOI Listing
October 2018
2 Reads

Down-regulation of let-7a and miR-21 in urine exosomes from lupus nephritis patients during disease flare.

Asian Pac J Allergy Immunol 2018 Aug 13. Epub 2018 Aug 13.

Center of Excellence in Immunology and Immune-mediated Disease, Faculty of Medicine, Chulalongkorn University, 10330, Thailand.

Background: The contents of exosomes determine their biological functions and represent a new class of epigenetic modulation of renal cells considering as novel class of biomarker.

Objective: Our study aims to investigate the expression of microRNAs (miRNA), including miR-10a/b, let-7a, and miR-21, in urinary exosomes isolated from patients with active lupus nephritis (LN) compared to inactive LN.

Methods: The exosomes were obtained from long-term follow up LN patients during active and 4 months after treatment (n = 3). Read More

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http://apjai-journal.org/wp-content/uploads/2018/08/AP-13031
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http://dx.doi.org/10.12932/AP-130318-0280DOI Listing
August 2018
2 Reads

Involvement of Toll-like receptor 2 on human corneal epithelium during an infection of Pythium insidiosum.

Asian Pac J Allergy Immunol 2018 Aug 13. Epub 2018 Aug 13.

Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Pythium insidiosum, a pathogenic oomycete, is a common causative organism of infectious corneal ulcer. Studying the innate immune response at the ocular surface is important for better understanding of the underlying pathogenesis and host defense against P. insidiosum infection. Read More

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http://apjai-journal.org/wp-content/uploads/2018/08/AP-11051
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http://dx.doi.org/10.12932/AP-110518-0311DOI Listing
August 2018
19 Reads

Role of Toll-like receptor 2 in mediating the production of cytokines and human beta-defensins in oral mucosal epithelial cell response to Leptospiral infection.

Asian Pac J Allergy Immunol 2018 Aug 13. Epub 2018 Aug 13.

Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.

Background: Pathogenic Leptospira spp. is the causative agent of leptospirosis. Oral mucosal cavity is one of portal entry for this bacterium. Read More

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http://apjai-journal.org/wp-content/uploads/2018/08/AP-10051
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http://dx.doi.org/10.12932/AP-100518-0308DOI Listing
August 2018
2 Reads

Clinical characteristics of exogenous progestogen hypersensitivity.

Asian Pac J Allergy Immunol 2018 Aug 13. Epub 2018 Aug 13.

Department of Internal Medicine, Pusan National University School of Medicine, Busan.

Background: Autoimmune progesterone dermatitis is a rare disease characterized by eruption recurrence in the luteal phase of each menstrual cycle. As synthetic progesterones are increasingly used for assisted reproductive techniques (ARTs) for infertility or prevention of abortion, cases of dermatitis caused by exogenous progesterone have been reported.

Objective: To investigate the clinical characteristics of exogenous progestogen hypersensitivity (PH). Read More

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http://dx.doi.org/10.12932/AP-291217-0227DOI Listing
August 2018
17 Reads

A hereditary angioedema screening on an index case: Turkey.

Asian Pac J Allergy Immunol 2018 Aug 13. Epub 2018 Aug 13.

Department of Pediatric Neurology, KahramanmarasSutcu Imam University Faculty of Medicine, Kahramanmaras, Turkey.

Background: Hereditary angioedema (HAE) is characterised by recurrent episodes of angioedema and can be fatal.

Objective: The present study aimed to screen HAE.

Methods: A total of 60 individuals were screened. Read More

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http://apjai-journal.org/wp-content/uploads/2018/08/AP-06021
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http://dx.doi.org/10.12932/AP-060218-0257DOI Listing
August 2018
28 Reads

Comparison between pediatric respiratory assessment measure (PRAM) score and wood asthma score to assess acute asthma exacerbation.

Asian Pac J Allergy Immunol 2018 Aug 13. Epub 2018 Aug 13.

Queen Sirikit National Institute of Child Health.

Background: Wood's score, the assessment of childhood respiratory failure, has been used to assess childhood acute asthma severity in Thailand since 19th century. However, PRAM score, which is increasingly used in Western countries has not been evaluated among Thai children with asthma.

Objectives: This study aims to determine whether Wood or PRAM score is better prediction of severity of childhood asthma exacerbation. Read More

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http://dx.doi.org/10.12932/AP-060118-0232DOI Listing

The cooperation of pharmacologic-dose ascorbate with ceftriaxone against Staphylococcus aureus through bactericidal synergy and enhanced macrophage killing activity.

Asian Pac J Allergy Immunol 2018 Aug 13. Epub 2018 Aug 13.

Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Ascorbate is a low-cost compound with a known bactericidal-synergy to antibitics. However, the synergy depends on concentrations and organisms. Thus, the synergy test by time-kill assay might be appropriate for the screening of the synergy. Read More

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http://dx.doi.org/10.12932/AP-171117-0200DOI Listing
August 2018
6 Reads

Effects of aerobic exercise and vitamin C supplementation on rhinitis symptoms in allergic rhinitis patients.

Asian Pac J Allergy Immunol 2018 Dec;36(4):222-231

Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand.

Introduction: Exercise training and vitamin C supplementation have both been recommended as an effective adjuvant treatment in the management of symptoms in patients with many diseases. However, its effects on rhinitis symptoms remain unclear. The aim of the present study was to determine the effects of exercise training alone, and in combination with vitamin C supplementation, on rhinitis symptoms in allergic rhinitis patients. Read More

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http://dx.doi.org/10.12932/AP-040417-0066DOI Listing
December 2018
3 Reads

Clinical and immunological characteristics of antiphospholipid syndrome in an Asian population: a retrospective study.

Asian Pac J Allergy Immunol 2018 Jul 8. Epub 2018 Jul 8.

Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand.

Objectives: To describe the characteristics of patients with antiphospholipid syndrome (APS) in an Asian clinical practice setting.

Methods: We conducted a single-center, retrospective study of APS patients attending the rheumatology or hematology clinics, between January 2012 and December 2016.

Results: There were 450 patients suspected of having APS referred to our clinics. Read More

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http://dx.doi.org/10.12932/AP-241217-0223DOI Listing
July 2018
1 Read

Randomized comparison of caregivers' ability to use epinephrine autoinjectors and prefilled syringes for anaphylaxis.

Asian Pac J Allergy Immunol 2018 Dec;36(4):248-256

Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

Background: Caregivers often incorrectly use epinephrine autoinjectors. It is unclear whether this is due to insufficient training or a difficult-to-use tool. Furthermore, the high costs of epinephrine autoinjectors may limit their availability; so low-cost prefilled syringes may be the alternative. Read More

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http://dx.doi.org/10.12932/AP-020318-0275DOI Listing
December 2018
3 Reads

The prevalence and sex difference of allergen sensitization among adult patients with allergic diseases in Shanghai, China.

Asian Pac J Allergy Immunol 2018 Jul 8. Epub 2018 Jul 8.

Department of Allergy, Renji Hospital, School of Medicine, Shanghai Jiao tong University, Shanghai, China.

Background: The worldwide prevalence of allergic diseases has increased during the last few decades, but it is not well known about the sensitization profiles of adult patients in Shanghai.

Objective: This study aimed to identify the prevalence and sex difference of allergen sensitization among adult with allergic diseases in Shanghai.

Methods: The sensitization profiles of 7,996 patients (18-60 yrs old) with allergic diseases at our center were retrospectively analyzed, based on the results of skin prick tests. Read More

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http://dx.doi.org/10.12932/AP-150118-0241DOI Listing
July 2018
1.250 Impact Factor