2,574 results match your criteria Asian Journal of Andrology[Journal]


Associations of preorchiectomy hormone levels to testicular germ cell tumor pathology, clinical stage, and size.

Asian J Androl 2020 Jun 19. Epub 2020 Jun 19.

The James Buchanan Brady Urological Institute, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.4103/aja.aja_27_20DOI Listing

Improving native human sperm freezing protection by using a modified vitrification method.

Asian J Androl 2020 Jun 16. Epub 2020 Jun 16.

Institute of Reproduction and Stem Cell Engineering, School of Basic Medicine Science, Central South University, Changsha 410000, China.

Slow freezing is the most commonly used technique for the cryopreservation of spermatozoa in clinical practice. However, it has been shown to have a negative impact on sperm function and structure. Vitrification as a successful alternative method has been proved to have better protective effects on human embryos, but vitrification of spermatozoa is still subject to low recovery rates. Read More

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http://dx.doi.org/10.4103/aja.aja_29_20DOI Listing

Testicular descent and fixation through a scrotal stria incision for the treatment of palpable cryptorchidism in children aged <3 years: 10-year experience with 1034 cases.

Asian J Androl 2020 Jun 12. Epub 2020 Jun 12.

Department of Pediatric Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001, China.

This study was performed to summarize our clinical experience with testicular descent and fixation through a scrotal stria incision for the treatment of palpable cryptorchidism in children. This study included 1034 children with palpable cryptorchidism from March 2009 to March 2019. A scrotal stria incision was used to perform testicular descent and fixation. Read More

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http://dx.doi.org/10.4103/aja.aja_24_20DOI Listing

Development and validation of a nomogram including lymphocyte-to-monocyte ratio for initial prostate biopsy: a double-center retrospective study.

Asian J Androl 2020 May 5. Epub 2020 May 5.

Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.

Here, we developed a prostate cancer (PCa) risk nomogram including lymphocyte-to-monocyte ratio (LMR) for initial prostate biopsy, and internal and external validation were further conducted. A prediction model was developed on a training set. Significant risk factors with P < 0. Read More

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http://dx.doi.org/10.4103/aja.aja_19_20DOI Listing

The presence of intraductal carcinoma of the prostate is closely associated with poor prognosis: a systematic review and meta-analysis.

Asian J Androl 2020 Jun 2. Epub 2020 Jun 2.

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

We aimed to confirm the predictive ability of the presence of intraductal carcinoma of the prostate (IDC-P) for prognosis and the associations between IDC-P and clinicopathological parameters. Studies were identified in PubMed, Cochrane Library, EMBASE, Web of Science, and SCOPUS up to December 1, 2019. Hazard ratios (HRs) for survival data and odds ratios for clinicopathological data with 95% confidence intervals (CIs) were extracted. Read More

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http://dx.doi.org/10.4103/aja.aja_21_20DOI Listing

The hamster egg penetration test may decrease intracytoplasmic sperm injection utilization while maintaining high conventional fertilization rates.

Asian J Androl 2020 May 19. Epub 2020 May 19.

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Utah, School of Medicine, Salt Lake City, UT 84132, USA.

This was a cohort study of in vitro fertilization (IVF) subjects at the University of Utah, Salt Lake City (UT, USA) utilizing partner sperm. Cycles where both the hamster egg penetration test (HEPT) and semen analysis were performed within 2 years prior to IVF cycles were stratified into four groups based on a normal or an abnormal HEPT and morphology. The mean conventional and intracytoplasmic sperm injection (ICSI) fertilization rates were calculated in each group. Read More

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http://dx.doi.org/10.4103/aja.aja_18_20DOI Listing

Androgen downregulation of miR-760 promotes prostate cancer cell growth by regulating IL6.

Asian J Androl 2020 May 15. Epub 2020 May 15.

Department of Urology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing 100142, China., China.

Prostate cancer (PCa) is one of the most common malignancies in Western countries. Studies have shown that androgen contributes to the progression of PCa, but how androgen promotes PCa remains largely unknown. Here, we demonstrated that androgen suppressed the expression of miR-760 depending on the interaction between androgen and androgen receptor (AR). Read More

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http://dx.doi.org/10.4103/aja.aja_20_20DOI Listing

N-acetylcysteine maintains penile length and erectile function in bilateral cavernous nerve crush rat model by reducing penile fibrosis.

Asian J Androl 2020 May 12. Epub 2020 May 12.

Andrology Laboratory, West China Hospital, Sichuan University, Chengdu 610041, China.

Penile length shortening and erectile dysfunction are common complications after radical prostatectomy. Various methods have been used to maintain erectile function, but less attention has been paid to preserving penis length. N-acetylcysteine (NAC) has the effect of antioxidation and antifibrotic, which may be beneficial to improve those postoperative complications. Read More

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http://dx.doi.org/10.4103/aja.aja_17_20DOI Listing

A novel approach: successful management of vasectomy reversal with a three-dimensional digital image microscope system.

Asian J Androl 2020 May 12. Epub 2020 May 12.

Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China.

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http://dx.doi.org/10.4103/aja.aja_15_20DOI Listing

The pelvic pop: an extremely rare case of internal penile fracture presenting with scrotal hematoma and review of the literature.

Asian J Androl 2020 May 5. Epub 2020 May 5.

Section of Urology, Department of Surgery, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.4103/aja.aja_14_20DOI Listing

Does intraoperative frozen section really predict significant positive surgical margins after robot-assisted laparoscopic prostatectomy? A retrospective study.

Asian J Androl 2020 May 1. Epub 2020 May 1.

Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul 05505, Korea.

We investigated the relationship between positive surgical margin (PSM)-related factors and biochemical recurrence (BCR) and the ability of intraoperative frozen sections to predict significant PSM in patients with prostate cancer. The study included 271 patients who underwent robot-assisted laparoscopic prostatectomy with bilateral nerve sparing and maximal urethral preservation. Intraoperative frozen sections of the periurethra, dorsal vein, and bladder neck were analyzed. Read More

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http://dx.doi.org/10.4103/aja.aja_16_20DOI Listing

The association between the two more common genetic causes of spermatogenic failure: a 7-year retrospective study.

Asian J Androl 2020 May 1. Epub 2020 May 1.

Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.

Chromosomal abnormalities and Y chromosome microdeletions are considered to be the two more common genetic causes of spermatogenic failure. However, the relationship between chromosomal aberrations and Y chromosome microdeletions is still unclear. This study was to investigate the incidence and characteristics of chromosomal aberrations and Y chromosome microdeletions in infertile men, and to explore whether there was a correlation between the two genetic defects of spermatogenic failure. Read More

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http://dx.doi.org/10.4103/aja.aja_13_20DOI Listing

Serum vitamin D content is associated with semen parameters and serum testosterone levels in men.

Asian J Androl 2020 Apr 28. Epub 2020 Apr 28.

Androscience, Science and Innovation Center in Andrology and High-Complex Clinical and Andrology Laboratory, Sao Paulo 04534-011, Brazil.

The present study aimed to evaluate the influence of serum vitamin D levels on semen quality and testosterone levels. This is a cross-sectional study conducted at Androscience, Science and Innovation Center in Andrology and High-Complex Clinical and Andrology Laboratory in Sao Paulo, Brazil, with 508 male patients, aged 18-60 years, from 2007 to 2017. Seminal parameters and serum sexual hormones were correlated with serum vitamin D concentrations in 260 men selected by strict selection criteria. Read More

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http://dx.doi.org/10.4103/aja.aja_9_20DOI Listing
April 2020
2.530 Impact Factor

Relationship of sperm plasma membrane and acrosomal integrities with sperm morphometry in .

Asian J Androl 2020 Apr 21. Epub 2020 Apr 21.

BIOFITER Research Group, Environmental Sciences Institute (IUCA), Department of Animal Production and Food Sciences, University of Zaragoza, Huesca 22071, Spain.

To date, sperm morphometric studies have assessed whole sperm populations without considering sperm function. The aim of this study was to evaluate the relationship of sperm membrane and acrosomal integrity with sperm morphometry in liquid semen samples collected from bulls. To this end, sperm morphometry was performed on cryopreserved semen samples from 16 bulls by a combination of fluorescent dyes, including Hoechst 33343, carboxyfluorescein diacetate, and propidium iodide. Read More

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http://dx.doi.org/10.4103/aja.aja_2_20DOI Listing

Sperm retrieval success and testicular histopathology in idiopathic nonobstructive azoospermia.

Asian J Androl 2020 Apr 21. Epub 2020 Apr 21.

Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

Prior studies have investigated sperm retrieval rates in men with nonobstructive azoospermia (NOA) secondary to specific etiologies, yet most cases of NOA are idiopathic. We compared sperm retrieval rates and testicular histopathology in idiopathic NOA (iNOA) and nonidiopathic NOA (niNOA). We performed a retrospective review of men with NOA who underwent microdissection testicular sperm extraction (microTESE) between 2000 and 2016. Read More

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http://dx.doi.org/10.4103/aja.aja_137_19DOI Listing

Sperm retrieval rates and clinical outcomes for patients with different causes of azoospermia who undergo microdissection testicular sperm extraction-intracytoplasmic sperm injection.

Asian J Androl 2020 Apr 21. Epub 2020 Apr 21.

Department of Urology, Peking University Third Hospital, Beijing 100191, China.

The aim of our study was to compare the sperm retrieval rates (SRRs) and clinical outcomes of patients with different causes of azoospermia who underwent microdissection testicular sperm extraction-intracytoplasmic sperm injection (micro-TESE-ICSI). We conducted a retrospective study at the Reproductive Medicine Center of Peking University Third Hospital in Beijing, China, from January 2014 to December 2017. This study examined 769 patients with nonobstructive azoospermia who underwent 347 cycles of micro-TESE-ICSI. Read More

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http://dx.doi.org/10.4103/aja.aja_12_20DOI Listing

Kinematic analysis of penile reflexes in a rat model of spinal cord injury.

Asian J Androl 2020 Apr 21. Epub 2020 Apr 21.

Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY 40202, USA.

The ex-copula penile dorsiflexion reflex (PDFR) is an established measure of sexual dysfunction in male rat models of spinal cord injury. Although the PDFR after complete spinal transection is well described, information regarding the more clinically relevant incomplete spinal contusion injury model is limited. This study examined, using two-dimensional (2D) kinematic analysis, the relationship between the PDFR and degree of white matter sparing (WMS). Read More

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http://dx.doi.org/10.4103/aja.aja_1_20DOI Listing

Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice.

Asian J Androl 2020 Apr 7. Epub 2020 Apr 7.

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.

The mammalian epididymis not only plays a fundamental role in the maturation of spermatozoa, but also provides protection against various stressors. The foremost among these is the threat posed by oxidative stress, which arises from an imbalance in reactive oxygen species and can elicit damage to cellular lipids, proteins, and nucleic acids. In mice, the risk of oxidative damage to spermatozoa is mitigated through the expression and secretion of glutathione peroxidase 5 (GPX5) as a major luminal scavenger in the proximal caput epididymidal segment. Read More

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http://dx.doi.org/10.4103/aja.aja_3_20DOI Listing
April 2020
2.530 Impact Factor

Comparative study of intracavernous pressure and cavernous pathology after bilateral cavernous nerve crushing and resection in rats.

Asian J Androl 2020 Mar 31. Epub 2020 Mar 31.

Molecular Biology Laboratory of Andrology Center, Peking University First Hospital, Peking University, Beijing 100034, China.

This study aimed to compare the effects of bilateral cavernous nerve crushing (BCNC) and bilateral cavernous nerve resection (BCNR) on intracavernous pressure (ICP) and cavernous pathology in rats and to explore the optimal treatment time for the BCNC and BCNR models. Seventy-two male rats aged 12 weeks were randomly divided into three equal groups: Sham (both cavernous nerves exposed only), BCNC (BCN crushed for 2 min), and BCNR (5 mm of BCN resected). Erectile function was then measured at 1 week, 3 weeks, and 5 weeks after nerve injury, and penile tissues were harvested for histological and molecular analyses by immunohistochemistry, immunofluorescence, Western blot, and cytokine array. Read More

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http://dx.doi.org/10.4103/aja.aja_10_20DOI Listing

Identification of sumoylated targets in proliferating mouse spermatogonia and human testicular seminomas.

Asian J Androl 2020 Mar 27. Epub 2020 Mar 27.

Department of Biology, Stern College, Yeshiva University, New York, NY 10016, USA.

Spermatogenesis is regulated by a complex network of posttranslation modifications. Sumoylation (a modification by small ubiquitin-like modifiers, or SUMO proteins) was identified as an important cellular event in different cell types. SUMO proteins are highly expressed in the testis, and their role during spermatogenesis has begun to be elucidated. Read More

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http://dx.doi.org/10.4103/aja.aja_11_20DOI Listing

Comparison of ART outcomes in men with altered mRNA protamine 1/protamine 2 ratio undergoing intracytoplasmic sperm injection with ejaculated and testicular spermatozoa.

Asian J Androl 2020 Mar 24. Epub 2020 Mar 24.

IVF-Spain, Alicante 03540, Spain.

Assisted reproductive technologies involving the use of spermatozoa and eggs for in vitro fertilization (IVF) have come as the solution for many infertile couples to become parents. However, in some cases, the use of ejaculated spermatozoa delivers poor IVF performance. Some studies have suggested the use of testicular spermatozoa in severe male infertility cases, but no guidelines regarding their utilization are currently available. Read More

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http://dx.doi.org/10.4103/aja.aja_146_19DOI Listing

MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer.

Asian J Androl 2020 Mar 10. Epub 2020 Mar 10.

Department of Urology, Changhai Hospital, Navy Medical University, Shanghai 200433, China.

Membrane-associated guanylate kinase (MAGUK) family protein MAGUK invert 2 (MAGI-2) has been demonstrated to be involved in the tumorigenic mechanism of prostate cancer. The objective of this study was to investigate the expression of MAGI-2 at mRNA and protein levels. The prognostic value of MAGI-2 in Han Chinese patients with prostate cancer was also investigated. Read More

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http://dx.doi.org/10.4103/aja.aja_142_19DOI Listing
March 2020
2.530 Impact Factor

When to pull the trigger in nonazoospermic infertile men undergoing intracytoplasmic sperm injection?

Asian J Androl 2020 Jul-Aug;22(4):439-440

Queens University Belfast, Northern Ireland BT71NN, UK.

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http://dx.doi.org/10.4103/aja.aja_4_20DOI Listing

Gene transcription profiling of astheno- and normo-zoospermic sperm subpopulations.

Asian J Androl 2020 Feb 14. Epub 2020 Feb 14.

Department of Reproduction Biology, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City 14080, Mexico.

Spermatozoa contain a repertoire of RNAs considered to be potential functional fertility biomarkers. In this study, the gene expression of human sperm subpopulations with high (F1) and low (F2) motility from healthy normozoospermic (N) and asthenozoospermic (A) individuals was evaluated using RNA microarray followed by functional genomic analysis of differentially expressed genes. Results from A-F1 versus N-F1, A-F2 versus N-F2, N-F1 versus N-F2, and A-F1 versus A-F2 comparisons showed a considerably larger set of downregulated genes in tests versus controls. Read More

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http://dx.doi.org/10.4103/aja.aja_143_19DOI Listing
February 2020

Artificial urinary sphincter: current status and future directions.

Authors:
Culley C Carson

Asian J Androl 2020 Mar-Apr;22(2):154-157

Department of Urology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Urge urinary incontinence (UUI) is one of the most troublesome complications of surgery of the prostate whether for malignancy or benign conditions. For many decades, there have been attempts to reduce the morbidity of this outcome with variable results. Since its development in the 1970s, the artificial urinary sphincter (AUS) has been the "gold standard" for treatment of the most severe cases of UUI. Read More

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http://dx.doi.org/10.4103/aja.aja_5_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155799PMC

Transurethral vesiculoscope-assisted laser incision of the prostatic utricle to treat partial ejaculatory duct obstruction.

Asian J Androl 2020 Mar 3. Epub 2020 Mar 3.

Department of Andrology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.

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http://dx.doi.org/10.4103/aja.aja_144_19DOI Listing
March 2020
2.530 Impact Factor

Introduction to the 12 Genitourinary Reconstructive Surgeons (GURS)-Masterclass special issue.

Asian J Androl 2020 Mar-Apr;22(2):123

Reconstructive Urology Unit, Institute of Urology, University College London Hospitals, London W1G 8PH, UK.

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http://dx.doi.org/10.4103/aja.aja_147_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155791PMC
February 2020

Metformin treatment of high-fat diet-fed obese male mice restores sperm function and fetal growth, without requiring weight loss.

Asian J Androl 2020 Feb 21. Epub 2020 Feb 21.

Robinson Research Institute, School of Medicine, University of Adelaide, Adelaide 5005, Australia.

Male obesity is associated with subfertility and increased disease risk of offspring. It is unknown if effects can be reversed through pharmacological interventions. Five- to 6-week-old C57BL6 male mice were fed control diet (n = 10, CD) or high-fat diet (n = 20, HFD) for 16 weeks. Read More

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http://dx.doi.org/10.4103/aja.aja_141_19DOI Listing
February 2020

Prognostic value of primary tumor surgery in seminoma patients with distant metastasis at diagnosis: a population-based study.

Asian J Androl 2020 Feb 4. Epub 2020 Feb 4.

Department of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.

The aims of this study were to determine the prognostic value of primary tumor surgery and identify optimal candidates for such surgery among patients with seminoma and distant metastasis at diagnosis. We identified 521 patients with seminoma and distant metastasis at diagnosis between 2004 and 2014 from the Surveillance, Epidemiology, and End Results database. Among these patients, 434 had undergone surgery, whereas 87 had not. Read More

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http://dx.doi.org/10.4103/aja.aja_140_19DOI Listing
February 2020
2.530 Impact Factor

How do we define "castration" in men on androgen deprivation therapy?

Asian J Androl 2020 Jan 21. Epub 2020 Jan 21.

Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL33328, USA.

Androgen deprivation therapy (ADT) is the mainstay for the treatment of advanced prostate cancer. Since the clinical evolution from surgical orchiectomy, we have typically used ADT and orchiectomy to be synonymous terms for castration. The goal of this study is to determine if, in contemporary medical practice, surgical and chemical castration provide for similar levels of diminishment of total and free testosterone. Read More

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http://dx.doi.org/10.4103/aja.aja_139_19DOI Listing
January 2020

Erectile function after WST11 vascular-targeted photodynamic therapy for low-risk prostate cancer treatment.

Asian J Androl 2020 Jan 14. Epub 2020 Jan 14.

Department of Urology, Angers University Hospital, Angers 49100, France.

Vascular-targeted photodynamic therapy (VTP) using padeliporfin is currently assessed as a low-risk prostate cancer (LRPCa) treatment. The aim of this study was to assess erectile function outcomes of VTP for LRPCa treatment. We prospectively included all patients treated with VTP for LRPCa. Read More

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http://dx.doi.org/10.4103/aja.aja_138_19DOI Listing
January 2020

Fluorescent probes for the detection of reactive oxygen species in human spermatozoa.

Asian J Androl 2020 Jan 14. Epub 2020 Jan 14.

Biology of Reproduction and Stem Cell Group, CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal.

Reactive oxygen species (ROS) production is a by-product of mitochondrial activity and is necessary for the acquisition of the capacitated state, a requirement for functional spermatozoa. However, an increase in oxidative stress, due to an abnormal production of ROS, has been shown to be related to loss of sperm function, highlighting the importance of an accurate detection of sperm ROS, given the specific nature of this cell. In this work, we tested a variety of commercially available fluorescent probes to detect ROS and reactive nitrogen species (RNS) in human sperm, to define their specificity. Read More

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http://dx.doi.org/10.4103/aja.aja_132_19DOI Listing
January 2020

Prostate volume does not provide additional predictive value to prostate health index for prostate cancer or clinically significant prostate cancer: results from a multicenter study in China.

Asian J Androl 2020 Jan 10. Epub 2020 Jan 10.

Department of Urology, Shanghai Changhai Hospital, The Second Military Medical University, Shanghai 200433, China.

To evaluate whether prostate volume (PV) would provide additional predictive utility to the prostate health index (phi) for predicting prostate cancer (PCa) or clinically significant prostate cancer, we designed a prospective, observational multicenter study in two prostate biopsy cohorts. Cohort 1 included 595 patients from three medical centers from 2012 to 2013, and Cohort 2 included 1025 patients from four medical centers from 2013 to 2014. Area under the receiver operating characteristic curves (AUC) and logistic regression models were used to evaluate the predictive performance of PV-based derivatives and models. Read More

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http://dx.doi.org/10.4103/aja.aja_136_19DOI Listing
January 2020
2.530 Impact Factor

Estradiol is an independent risk factor for organic erectile dysfunction in eugonadal young men.

Asian J Androl 2020 Jan 10. Epub 2020 Jan 10.

Department of Andrology, The Center for Men's Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China.

Erectile dysfunction attributable to testosterone deficiency is less common in young males, and the effect of estradiol on erectile function in eugonadal young males is unclear. We analyzed data from 195 male participants, including 143 eugonadal patients with erectile dysfunction and 52 healthy men. To distinguish psychogenic and organic erectile dysfunction, penile rigidity was measured using the nocturnal penile tumescence rigidity test. Read More

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http://dx.doi.org/10.4103/aja.aja_135_19DOI Listing
January 2020

Tissue expander capsule as an induced vascular bed to prefabricate an axial vascularized buccal mucosa-lined flap for tubularized posterior urethral reconstruction: preliminary results in an animal model.

Asian J Androl 2020 Jan 10. Epub 2020 Jan 10.

Department of Urology, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200062, China.

Surgical repair of complex posterior urethral disruptions remains one of the most challenging problems in urology. The efficacy of using a tissue expander capsule as an induced vascular bed to prefabricate axial vascularized buccal mucosa-lined flaps for tubularized posterior urethral reconstruction in a rabbit model was tested. The experiments were performed in three stages. Read More

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http://dx.doi.org/10.4103/aja.aja_133_19DOI Listing
January 2020

Chromosome heteromorphisms: do they entail a reproductive risk for male carriers?

Asian J Androl 2020 Jan 10. Epub 2020 Jan 10.

Genetics of Male Fertility Group, Cell Biology Unit, Faculty of Biosciences, Autonomous University of Barcelona, Bellaterra (Cerdanyola del Vallès) 08193, Spain.

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http://dx.doi.org/10.4103/aja.aja_130_19DOI Listing
January 2020

Sexual health in Polish elderly men with coronary artery disease: importance, expectations, and reality.

Asian J Androl 2020 Jan 7. Epub 2020 Jan 7.

Cardiosexology Unit, Department of Pathophysiology, Wrocław Medical University, Wrocław 50-368, Poland.

Deterioration in overall health, hormonal disturbances, and erectile dysfunction (ED) contributes to limitations in sexual activity in the elderly, which is further limited by incorrect beliefs about the hazards of sexual activity in cardiac patients. We aimed to analyze the occurrence of ED in elderly men, their perception of the relevance of good sexual function, and their expectations of physicians. A cross-sectional study encompassed 731 patients with coronary artery disease (CAD) subjected to cardiac rehabilitation. Read More

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http://dx.doi.org/10.4103/aja.aja_131_19DOI Listing
January 2020

Real-time transrectal ultrasound-guided seminal vesiculoscopy for the treatment of patients with persistent hematospermia: A single-center, prospective, observational study.

Asian J Androl 2019 Dec 27. Epub 2019 Dec 27.

Department of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.

This study aimed to describe endoscopic anatomy of the seminal tract and summarize our experience of transutricular seminal vesiculoscopy (TSV) guided by real-time transrectal ultrasonography (TRUS) in managing persistent hematospermia. A total of 281 consecutive patients with persistent hematospermia who underwent TSV with or without real-time TRUS were enrolled in this single-center, prospective, observational study. The median follow-up period was 36. Read More

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http://dx.doi.org/10.4103/aja.aja_134_19DOI Listing
December 2019

National natural science foundation of China leads the comprehensive development of basic research in the field of male reproductive health in China.

Asian J Androl 2019 Dec 27. Epub 2019 Dec 27.

Department of Health Science, National Natural Science Foundation of China, Beijing 100085, China.

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http://dx.doi.org/10.4103/aja.aja_129_19DOI Listing
December 2019

Transurethral resection of the prostate stricture management.

Asian J Androl 2020 Mar-Apr;22(2):140-144

Department of Urology, Beijing Jishuitan Hospital, The Fourth Medical College of Peking University, Beijing 100096, China.

For more than nine decades, transurethral resection of the prostate remains the gold standard for the surgical treatment of lower urinary tract symptoms due to benign prostatic obstruction. The occurrence of urethral strictures after transurethral resection of the prostate is one of the major late complications and has been reported as the leading cause of iatrogenic urethral strictures in patients older than 45 years who underwent urethroplasty. Although several postulations have been proposed to explain the urethral stricture after transurethral resection of the prostate, the exact etiology of urethral stricture after TURP is still controversial. Read More

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http://dx.doi.org/10.4103/aja.aja_126_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155786PMC
January 2020

Novel protective penile collar following inflatable penile prosthesis placement: The "Wang Collar".

Asian J Androl 2019 Dec 17. Epub 2019 Dec 17.

St. Joseph Medical Center, Houston, TX 77002, USA.

Penile rehabilitation after inflatable penile prosthesis (IPP) implantation for the treatment of erectile dysfunction includes leaving the device partially inflated so as to preserve the penile length and to maintain hemostasis. With a partially inflated device, the penis becomes more sensitive and more susceptible to unintended insults during the immediate postoperative management. The "Wang Collar," a device intended to protect the penis in the early postoperative period, is hereby described. Read More

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http://dx.doi.org/10.4103/aja.aja_123_19DOI Listing
December 2019

Penile prosthesis implant in the special populations: diabetics, neurogenic conditions, fibrotic cases, concurrent urinary continence surgery, and salvage implants.

Authors:
Eric Chung

Asian J Androl 2020 Jan-Feb;22(1):39-44

AndroUrology Centre, Brisbane, QLD 4000, Australia.

Penile prosthesis implant (PPI) remains an effective and safe treatment option for men with erectile dysfunction (ED). However, PPI surgery can be associated with a higher risk of complications in certain populations. This article provides a critical review of relevant publications pertaining to PPI in men with diabetes, significant corporal fibrosis, spinal cord injury, concurrent continence surgery, and complex salvage cases. Read More

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http://dx.doi.org/10.4103/aja.aja_127_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958981PMC
December 2019

Artificial urinary sphincter surgery in the special populations: neurological, revision, concurrent penile prosthesis and female stress urinary incontinence groups.

Authors:
Eric Chung

Asian J Androl 2020 Jan-Feb;22(1):45-50

AndroUrology Centre, Brisbane, QLD 4000, Australia.

The artificial urinary sphincter (AUS) remains the standard of care in men with severe stress urinary incontinence (SUI) following prostate surgery and radiation. While the current AUS provides an effective, safe, and durable treatment option, it is not without its limitations and complications, especially with regard to its utility in some "high-risk" populations. This article provides a critical review of relevant publications pertaining to AUS surgery in specific high-risk groups such as men with spinal cord injury, revision cases, concurrent penile prosthesis implant, and female SUI. Read More

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http://dx.doi.org/10.4103/aja.aja_128_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958990PMC
December 2019

Epidemiology regarding penile prosthetic surgery.

Asian J Androl 2020 Jan-Feb;22(1):2-7

Department of Surgery/Division of Urology, University of Texas Medical Science Center at Houston, Houston, TX 77030, USA.

With the onset of a metabolic syndrome epidemic and the increasing life expectancy, erectile dysfunction (ED) has become a more common condition. As incidence and prevalence increase, the medical field is focused on providing more appropriate therapies. It is common knowledge that ED is a chronic condition that is also associated with a myriad of other disorders. Read More

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http://dx.doi.org/10.4103/aja.aja_124_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958974PMC
December 2019

Microsurgical subinguinal varicocelectomy with spermatic cord double traction and vein stripping.

Asian J Androl 2020 Mar-Apr;22(2):208-212

Department of Andrology, Center for Men's Health, Department of ART, Urologic Medical Center, Shanghai General Hospital, Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University, Shanghai 200080, China.

We retrospectively reviewed data for 286 patients with varicocele who underwent microsurgical subinguinal varicocelectomy from March 2015 to May 2017 in Shanghai General Hospital (Shanghai, China). In this surgical approach, the testis was delivered, and the gubernacular and external cremasteric veins were stripped. In addition, the spermatic cord was delivered downward with continuous double traction away from the external ring. Read More

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http://dx.doi.org/10.4103/aja.aja_118_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155800PMC
December 2019

The modern testicular prosthesis: patient selection and counseling, surgical technique, and outcomes.

Asian J Androl 2020 Jan-Feb;22(1):64-69

Department of Urology, University of North Carolina School of Medicine, Chapel Hill, NC 27500-7235, USA.

The testicular prosthesis can be an afterthought for providers when performing an orchiectomy for testicular cancer, torsion, atrophic testis, or trauma. However, data suggest that patients find the offer of a testicular prosthesis and counseling regarding placement to be extremely important from both a pragmatic and a psychosocial perspective. Only two-thirds of men undergoing orchiectomy are offered an implant at the time of orchiectomy and of those offered about one-third move forward with prosthesis placement. Read More

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http://dx.doi.org/10.4103/aja.aja_93_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958971PMC
November 2019

Prokineticin 2 overexpression induces spermatocyte apoptosis in varicocele in rats.

Asian J Androl 2019 Nov 19. Epub 2019 Nov 19.

Family Planning Research Institute/Reproductive Medicine Center, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Varicocele is one of the most important causes of male infertility, as this condition leads to a decline in sperm quality. It is generally believed that the presence of varicocele induces an increase in reactive oxygen species levels, leading to oxidative stress and sperm apoptosis; however, the specific pathogenic mechanisms affecting spermatogenesis remain elusive. Prokineticin 2 (PK2), a secretory protein, is associated with multiple biological processes, including cell migration, proliferation, and apoptosis. Read More

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http://dx.doi.org/10.4103/aja.aja_109_19DOI Listing
November 2019

Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) depletion regulates spermatogenic cell apoptosis and is correlated with hypospermatogenesis.

Asian J Androl 2019 Nov 15. Epub 2019 Nov 15.

Department of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China.

Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) is a rate-limiting enzyme and plays an important role in purine and pyrimidine nucleotide synthesis. Recent studies report that PRPS2 is involved in male infertility. However, the role of PRPS2 in hypospermatogenesis is unknown. Read More

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http://dx.doi.org/10.4103/aja.aja_122_19DOI Listing
November 2019