187,655 results match your criteria Asian Journal Of Womens Studies[Journal]


Latent pseudorabies virus infection in medulla oblongata from quarantined pigs.

Transbound Emerg Dis 2020 Jul 2. Epub 2020 Jul 2.

Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

Pseudorabies virus (PRV) is a major pathogen in pig husbandry, and is also a risk to human well-being. Pigs with latent PRV infection carry the virus lifelong, and it can be activated under conducive conditions. This poses a very important challenge to the control of the virus, and may even prevent its elimination. Read More

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http://dx.doi.org/10.1111/tbed.13712DOI Listing

The role of 5-HTTLPR in autism spectrum disorder: New evidence and a meta-analysis of this polymorphism in Latin American population with psychiatric disorders.

PLoS One 2020 2;15(7):e0235512. Epub 2020 Jul 2.

Departamento de Ciencias Biológicas, Universidad de los Andes, Bogotá, Colombia.

The autism spectrum disorder (ASD) is a complex disorder encompassing a broad phenotypic and genotypic variability. The short (S)/long (L) 5-HTTLPR polymorphism has a functional role in the regulation of extracellular serotonin levels and both alleles have been associated to ASD. Most studies including European, American, and Asian populations have suggested an ethnical heterogeneity of this polymorphism; however, the short/long frequencies from Latin American population have been under-studied in recent meta-analysis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235512PLOS

Tacrolimus trough levels higher than 6 ng/mL might not be required after a year in stable kidney transplant recipients.

PLoS One 2020 2;15(7):e0235418. Epub 2020 Jul 2.

Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.

Background: Little is known regarding optimal tacrolimus (TAC) trough levels after 1 year post-transplant in stable kidney transplant recipients (KTRs) who have not experienced renal or cardiovascular outcomes. This study aimed to investigate the effect of 1-year post-transplant TAC trough levels on long-term renal and cardiovascular outcomes and opportunistic infections in stable KTRs.

Methods: KTRs receiving TAC with mycophenolate-based immunosuppression who did not experience renal or cardiovascular outcomes within 1 year post-transplant were enrolled from a multicenter observational cohort study. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235418PLOS

Similarities and differences in COVID-19 awareness, concern, and symptoms by race and ethnicity in the United States: A cross-sectional survey.

J Med Internet Res 2020 Jul 1. Epub 2020 Jul 1.

Department of Behavioral, Social and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, US.

Background: Existing health disparities based on race and ethnicity in the United States are contributing to disparities in morbidity and mortality in the COVID-19 pandemic. We conducted an online survey of American adults to assess similarities and differences by race and ethnicity groups with respect to COVID-19 symptoms, estimates of the extent of the pandemic, knowledge of control measures, and stigma.

Objective: Describe similarities and differences in COVID-19 symptoms, knowledge, and beliefs by race and ethnicity among adults in the US. Read More

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http://dx.doi.org/10.2196/20001DOI Listing

Chemical constituents from the stems of with their inhibitory activity on α-glucosidase.

J Asian Nat Prod Res 2020 Jul 2:1-6. Epub 2020 Jul 2.

Department of Pharmacy, Jingjiang People's Hospital, Jingjiang 214500, China.

A new aurone named (2)-2-[(4'-hydroxy-3'-methoxyphenyl) methylene]-6-methoxy-7-prenyl-3(2)-benzofurane (), together with five known compounds (), were isolated from EtOAc-soluble extract of the stems of . The chemical structures were elucidated on the basis of spectroscopic analyses. All isolates were evaluated for inhibitory activity on α-glucosidase. Read More

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http://dx.doi.org/10.1080/10286020.2020.1783657DOI Listing

A new prenylated coumestan from the roots of .

J Asian Nat Prod Res 2020 Jul 2:1-7. Epub 2020 Jul 2.

Institute of Materia Medica, Dali University, Dali 671000, China.

A new prenylated coumestan, campylohirtin A (), along with fifteen phenolic known compounds () and four other known compounds (), was obtained from the 95% ethanol extract of roots of . Their structures were elucidated based on extensive spectroscopic analysis (1 D and 2 D-NMR, MS, UV and IR). antimalarial activities of compounds -, - and were evaluated by -hematin formation inhibition assay. Read More

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http://dx.doi.org/10.1080/10286020.2020.1779706DOI Listing

Anthraquinone analogues with inhibitory activities against influenza a virus from .

J Asian Nat Prod Res 2020 Jul 2:1-7. Epub 2020 Jul 2.

Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.

Three anthraquinone analogues (-) were isolated by phytochemical work on EtOAc-soluble ingredients extracted from the roots of . The structures of all isolates were elucidated by NMR, MS and CD experiments, of which (polygodoquinone A) was identified as a new anthraquinone derivative. Specifically, represents an unusual structure composed of a naphthoquinone derivative linked to an anthraquinone via a C-C bond. Read More

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http://dx.doi.org/10.1080/10286020.2020.1779707DOI Listing

Supramolecular Tubule from Seesaw Shaped Amphiphile and Its Hierarchical Evolution into Sheet.

Chem Asian J 2020 Jul 2. Epub 2020 Jul 2.

Fudan University, Department of Chemistry, 2005 Songhu Road, 200438, Shanghai, CHINA.

Although supramolecular one-dimensional (1D) and two-dimensional (2D) structures with various unique properties have been extensively studied, the reversible switching between tubules and sheets via lateral association remains challenging. Here, we report the unique structures of a supramolecular tubular bamboo culm in which the hollow-tubular interior is separated, at intervals, by nodes per 1.3 nm. Read More

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http://dx.doi.org/10.1002/asia.202000654DOI Listing

Post-Admixture Selection on Chileans Targets Haplotype Involved in Pigmentation and Immune Defense Against Pathogens.

Genome Biol Evol 2020 Jul 2. Epub 2020 Jul 2.

Faculty of Engineering and Sciences, Universidad Adolfo Ibañez, Diagonal Las Torres 2700, Peñalolén, Santiago, Chile.

Detection of positive selection signatures in populations around the world is helping to uncover recent human evolutionary history as well as the genetic basis of diseases. Most human evolutionary genomic studies have been performed in European, African and Asian populations. However, populations with Native American ancestry have been largely underrepresented. Read More

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http://dx.doi.org/10.1093/gbe/evaa136DOI Listing

Corrigendum to "Frequency of risk factors in patients of acute coronary syndrome due to coronary ectasia".

Authors:

Asian Cardiovasc Thorac Ann 2020 Jul 2:218492320942444. Epub 2020 Jul 2.

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http://dx.doi.org/10.1177/0218492320942444DOI Listing

Acculturation processes and mental health of Asian Indian women in the United States: A mixed-methods study.

Am J Orthopsychiatry 2020 ;90(4):510-522

Department of Psychology, University of North Texas.

Acculturation theories and research find that both new culture acquisition and heritage culture attachment are associated with positive outcomes. However, gender-related analyses are rare. In this mixed-method study of 73 Asian Indian American women who were first- or second-generation immigrants from Kerala, India, those classified as behaviorally bicultural, assimilated, separated, or marginalized did not differ significantly in well-being. Read More

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http://dx.doi.org/10.1037/ort0000465DOI Listing
January 2020

Meta analysis of the relationship between methylenetetrahydrofolate reductase C677T and A1298C polymorphism and Venous thromboembolism in the Caucasian and Asian.

Biosci Rep 2020 Jul 2. Epub 2020 Jul 2.

The First Affiliated Hospital of Air Force Medical University (XiJing Hospital), Xi'an, China.

Recent years, it is a highly debated topic that whether methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and A1298C polymorphism could increase susceptibility to venous thromboembolism (VTE) in the Asian and Caucasian. Therefore, we expect to settle that controversy evidentially. Basic methods: Electronic databases (Pubmed, embase, Cochrane library, scopus, OvidSP, Wiley Online library, Springer link, EBSCO, Elsevier Science Direct, Google scholar) without date limitation were searched. Read More

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http://dx.doi.org/10.1042/BSR20200860DOI Listing

Decacyclene radical anions showing strong low-energy intramolecular absorption and magnetic coupling of spins in a hexagonal network.

Chem Asian J 2020 Jul 1. Epub 2020 Jul 1.

Institute of Problem of Chemical Physics RAS, Kinetics and catalysis, 142432, Chernogolovka, RUSSIAN FEDERATION.

Two salts of the aromatic hydrocarbon decacyclene, {cryptand[2.2.2](Cs + )} (decacyclene ·- ) ( 1 ) and {Bu 3 MeP + }(decacyclene ·- ) ( 2 ), were obtained. Read More

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http://dx.doi.org/10.1002/asia.202000615DOI Listing

Recent Advances in the Preparation and Applications of organo- functionalized Porous Materials.

Chem Asian J 2020 Jul 1. Epub 2020 Jul 1.

University of Newcastle, Global Innovative Center for Advanced Nanomaterials, University Drive, Callaghan 2308, 2308, Newcastle, AUSTRALIA.

Organo-functionalized materials with porous structure offer unique adsorption, catalytic and sensing properties. These unique properties make them available for various applications, including catalysis, CO 2 capture and utilization, and drug delivery. The properties and the performance of these unique materials can be altered with suitable modifications on their surface. Read More

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http://dx.doi.org/10.1002/asia.202000651DOI Listing

A study into the drug dupilumab in Japanese adults with moderate-to-severe atopic dermatitis.

Authors:

Br J Dermatol 2020 Jul;183(1):e4-e30

Atopic dermatitis (AD), a long-lasting skin disease characterized by intense itching and dry, red, swollen and cracked skin, affects between 2% and 10% of Japanese adults. In Japan, patients with moderate-to-severe or very severe AD have limited treatment options, most with unwanted side effects. There is a need for therapies that provide safe and effective long-term control. Read More

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http://dx.doi.org/10.1111/bjd.19174DOI Listing

Statin use and the risk of multiple myeloma: a PRISMA-compliant meta-analysis.

Ann Hematol 2020 Jun 29. Epub 2020 Jun 29.

State Key Laboratory of Proteomics, Academy of Military Medical Sciences, Academy of Military Sciences, Beijing, 100071, China.

Previous studies exploring associations between statin use and risk of multiple myeloma (MM) showed inconsistent results. We searched for articles published in English in databases (PubMed, Web of Science, EMBASE, Medline, and Google Scholar) before October 2019. The multivariate odds ratio (OR)/relative risk (RR) and 95% confidence intervals (CI) were computed to explore associations between statin use and risk of MM. Read More

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http://dx.doi.org/10.1007/s00277-020-04157-5DOI Listing

Corneal melt following corneal tattooing with carbon-based ink.

Am J Ophthalmol Case Rep 2020 Sep 10;19:100779. Epub 2020 Jun 10.

Asian Eye Institute, Makati, Philippines.

Purpose: to report a case of corneal melting following corneal tattooing with carbon-based ink.

Observations: A 67 year old female with a phthisical eye underwent corneal tattooing with carbon-based ink for purpose of cosmesis. The procedure was uncomplicated. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315104PMC
September 2020

Black, Asian and Minority Ethnic groups in England are at increased risk of death from COVID-19: indirect standardisation of NHS mortality data.

Wellcome Open Res 2020 6;5:88. Epub 2020 May 6.

UCL Collaborative Centre for Inclusion Health, Institute of Epidemiology and Health Care, UCL, London, WC1E 7HB, UK.

: International and UK data suggest that Black, Asian and Minority Ethnic (BAME) groups are at increased risk of infection and death from COVID-19. We aimed to explore the risk of death in minority ethnic groups in England using data reported by NHS England. : We used NHS data on patients with a positive COVID-19 test who died in hospitals in England published on 28th April, with deaths by ethnicity available from 1st March 2020 up to 5pm on 21 April 2020. Read More

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http://dx.doi.org/10.12688/wellcomeopenres.15922.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317462PMC

A comparison of cardiovascular risk scores in native and migrant South Asian populations.

SSM Popul Health 2020 Aug 11;11:100594. Epub 2020 May 11.

Freeman Hospital, Newcastle-upon-Tyne, UK.

Background: South Asians have increased cardiovascular risk burden but little data exists comparing cardiovascular (CV) risk models in migrant and native South Asians. Our retrospective cohort study in patients presenting with first acute myocardial infarction(MI) compares the predictive value of CV risk scores in native and UK migrant South Asians.

Methods: Retrospective cohort study of 80 UK-based patients of South Asian origin admitted with first presentation MI, excluding patients with known coronary artery disease. Read More

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http://dx.doi.org/10.1016/j.ssmph.2020.100594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322355PMC

Primary Tumor Location as a Prognostic and Predictive Marker in Metastatic Colorectal Cancer (mCRC).

Front Oncol 2020 16;10:964. Epub 2020 Jun 16.

Department of Medical Oncology, Amrita Institute of Medial Sciences and Research Centre, Kochi, India.

Clinico-pathological differences between adenocarcinoma in the right and left colo-rectum play a role in determining the prognosis and response to treatment. Studies suggest that primary tumor location is more relevant as the disease progresses and reflects a possible difference in biology and response to therapy. This review aims to explore the clinico-pathological features of right and left colo-rectum and the impact of primary tumor location on prognosis of CRC as well as discuss the available clinical data on tumor sidedness in metastatic colorectal cancer. Read More

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http://dx.doi.org/10.3389/fonc.2020.00964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309590PMC

Association between maternal age at delivery and allergic rhinitis in schoolchildren: A population-based study.

World Allergy Organ J 2020 Jun 23;13(6):100127. Epub 2020 Jun 23.

Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Background: Some studies have shown associations of maternal age at delivery with asthma and food allergy in offspring. However, the relationship between maternal age at delivery and allergic rhinitis is largely unclear. This study aimed to investigate the association between maternal age at delivery and allergic rhinitis in a population sample of Asian children, and to explore potential effect modifiers. Read More

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http://dx.doi.org/10.1016/j.waojou.2020.100127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322179PMC

Roadwork: expertise at work building roads in the Maldives.

J R Anthropol Inst 2020 Jun 23;26(2):284-301. Epub 2020 Mar 23.

University of Edinburgh 5.20 Chrystal Macmillan Building, 15a George Square Edinburgh EH8 9LD UK.

This article engages critically with concepts of 'skill', 'expertise', and 'capacity' as they operate as markers of distinction and domination and shape migratory labour relations among road construction workers from across South Asia in the Maldives archipelago. The article examines roadwork at three levels: the professional biographies leading to 'flexible specialization' rather than technical expertise amongst Maldivian managers; the technical expertise and social incorporation of 'skilled' Sri Lankan supervisors; and the key material expertise of 'non-skilled' Bangladeshi labourers in precarious employment. Whilst discussions of South Asian labour migration have been dominated by caste and class, this article argues that it is important to consider how the cultural production and understanding of concepts such as 'expertise', 'capacity', and 'exposure' at worksites can (also) become distinguishing factors in (hierarchical) migratory labour relations. Read More

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http://dx.doi.org/10.1111/1467-9655.13236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319434PMC

Four new species of Asian horned toads (Anura, Megophryidae, ) from southern China.

Zookeys 2020 18;942:105-140. Epub 2020 Jun 18.

State Key Laboratory of Biocontrol/ The Museum of Biology, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.

Recent phylogenetic analysis encompassing multilocus nuclear-gene and matrilineal mtDNA genealogy has revealed a series of cryptic species of the subgenus Panophrys within genus from southern and eastern China. This study demonstrates that the specimens from the hilly areas among Guangdong, Guangxi and Hunan can be morphologically distinguished from all recognized congeners, thereby providing additional supports for the recognitions of four new species of , namely Megophrys (Panophrys) mirabilis Lyu, Wang & Zhao, from northeastern Guangxi, Megophrys (Panophrys) shimentaina Lyu, Liu & Wang, from northern Guangdong, and Megophrys (Panophrys) xiangnanensis Lyu, Zeng & Wang, and Megophrys (Panophrys) yangmingensis Lyu, Zeng & Wang, from southern Hunan. The descriptions of these species take the number of species to 101, 46 of which belong to the subgenus Panophrys. Read More

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http://dx.doi.org/10.3897/zookeys..47983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316820PMC

Chinese Cancer Research in 2009-18 and the Disease Burden.

Cancer Manag Res 2020 25;12:5031-5040. Epub 2020 Jun 25.

King's College London, Institute of Cancer Policy, Guy's Hospital, London SE1 9RT, UK.

Objective: We investigated the correlation of cancer research in China with its disease burden and national or provincial wealth. We also compared China's research output with that of other Asian countries.

Methods: Chinese publications on cancer research for 2009-18 were retrieved from the Web of Science with a special filter giving high precision and recall. Read More

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http://dx.doi.org/10.2147/CMAR.S253276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323809PMC

Medicolegal Consideration to Prevent Medical Malpractice Regarding Opioid Administration: An Analysis of Judicial Opinion in South Korea.

J Pain Res 2020 25;13:1525-1532. Epub 2020 Jun 25.

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

Purpose: Although the use of opioids is increasing in South Korea, there have been no studies on the serious complications caused by the opioids. The aim of this study was to investigate the rare but serious complications through medicolegal analysis.

Materials And Methods: From January 1994 to December 2019, we retrospectively reviewed the closed cases of lawsuits involving the complications of opioids using the database of judgments of the Supreme Court of Korea. Read More

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http://dx.doi.org/10.2147/JPR.S256759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323961PMC

Remogliflozin Etabonate in the Treatment of Type 2 Diabetes: Design, Development, and Place in Therapy.

Drug Des Devel Ther 2020 24;14:2487-2501. Epub 2020 Jun 24.

Deptartment of Endocrinology, IPGME&R and SSKM Hospital, Kolkata, India.

Type 2 diabetes mellitus (T2DM) is an emerging epidemic in Asian countries, especially in India. With the advent of the SGLT2 inhibitor class of drugs demonstrating benefits beyond glycemic control, viz. weight loss, blood pressure reduction, and cardiovascular and renal protection, the management of T2DM has taken a quantum leap. Read More

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http://dx.doi.org/10.2147/DDDT.S221093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322139PMC

Optimal Gestational Weight Gain for Tibetans Based on Prepregnancy Body Mass Index.

Sci Rep 2020 Jul 1;10(1):10690. Epub 2020 Jul 1.

Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.

We aimed to estimate the optimal gestational weight gain (GWG) in Tibetan women and to evaluate the appropriateness of the Institute of Medicine (IOM) GWG recommendations for Tibetan women. We analyzed data from 1474 Tibetan women from a cross-sectional study conducted in 2019. According to the three different body mass index (BMI) classification criteria (WHO BMI categories, WHO Asian BMI categories, Chinese BMI categories), we estimated the association of GWG with pregnancy outcomes (neonate birthweight and mode of delivery) using a polynomial regression model, and the optimal GWG in each BMI group was calculated. Read More

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http://dx.doi.org/10.1038/s41598-020-65725-3DOI Listing

Polar Lipid Fraction from Golden Oyster Mushrooms (Pleurotus citrinopileatus) Suppresses Colon Injuries from Inflammatory Stresses in vivo and in vitro.

J Oleo Sci 2020 ;69(7):751-757

Department of Life and Food Science, Obihiro University of Agriculture and Veterinary Medicine.

The rising incidence of inflammatory bowel disease (IBD) in East Asian countries has necessitated the implementation of preventive methods in the form of dietary supplementation and changes in dietary habits. We have previously reported that dietary golden oyster mushroom (Pleurotus citrinopileatus) ethanol extract (GOMEE) suppresses intestinal inflammation in mouse models of IBD induced by dextran sulfate sodium salt (DSS). Here, we investigated the components of GOMEE that exert suppressive effects on colon inflammation in vivo and in vitro. Read More

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http://dx.doi.org/10.5650/jos.ess20050DOI Listing
January 2020

Impact of COVID-19 pandemic on health system & Sustainable Development Goal 3.

Indian J Med Res 2020 May;151(5):395-399

Former Director, Communicable Diseases, World Health Organization South-East Asia Region Office, New Delhi 110 002, India.

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http://dx.doi.org/10.4103/ijmr.IJMR_1920_20DOI Listing

Social Distance Towards Mental Illness Among Undergraduate Pharmacy Students in a Nigerian University.

East Asian Arch Psychiatry 2020 Jun;30(2):57-62

Lyn-Edge Pharmaceuticals Limited, Port-Harcourt City, Rivers State, Nigeria.

Objectives: To evaluate the level of social distance towards people with mental illness among pharmacy students in a Nigerian university and to explore its associated factors.

Methods: A cross-sectional survey was conducted among 433 pharmacy students in University of Nigeria, Nsukka. The 8-item Social Distance Scale was used to assess an individuals' avoidance reaction directed towards people with mental disorder. Read More

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http://dx.doi.org/10.12809/eaap1924DOI Listing

Mindfulness-based Cognitive Therapy for Generalised Anxiety Disorder: a Systematic Review and Meta-analysis.

East Asian Arch Psychiatry 2020 Jun;30(2):52-56

Addiction Researches Department, Center of Excellence in Psychiatry, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, Iran.

Background: Generalised anxiety disorder (GAD) has harmful effects on physical and mental health and quality of life. Mindfulness-based cognitive therapy (MBCT) is a treatment option for GAD. This meta-analysis was conducted to determine the effectiveness of MBCT on GAD. Read More

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http://dx.doi.org/10.12809/eaap1885DOI Listing

Validity and Reliability of the Thai Version of the Short Mood and Feelings Questionnaire.

East Asian Arch Psychiatry 2020 Jun;30(2):48-51

Thammasat University Hospital, Pathumthani, Thailand.

Objective: To evaluate the validity and reliability of a Thai version of the Short Mood and Feelings Questionnaire (SMFQ).

Methods: The present study included 23 children with depressive disorders (diagnosis made by child psychiatrists) and 74 children with no depressive disorders. All children and their parents were asked to complete the Thai versions of the SMFQ, Children's Depression Inventory, and Mood and Feelings Questionnaire. Read More

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http://dx.doi.org/10.12809/eaap1875DOI Listing

Reliability and Validity of Persian Version of State-Trait Anxiety Inventory Among High School Students.

East Asian Arch Psychiatry 2020 Jun;30(2):44-47

Substance Abuse Prevention Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Objectives: The aim of the present study was to assess the reliability and validity of the Persian version of the State-Trait Anxiety Inventory Form Y (STAI-Y) among high school students.

Methods: A sample of 492 high school students in Kermanshah city, Iran were randomly selected via multistage sampling. They were asked to complete the STAI-Y and Beck Anxiety Inventory (BAI) to determine the correlation coefficients. Read More

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http://dx.doi.org/10.12809/eaap1870DOI Listing

Survival of Melancholia: a Retrospective Study of Patients with Depressive Disorders.

East Asian Arch Psychiatry 2020 Jun;30(2):39-43

Department of Psychiatry, Ludwig Maximilian University, Germany.

Background: The DSM-IV and the DSM-5 eliminated the importance of the syndromal identity of melancholic depression in favour of a dimensional model within the domain of major depressive disorders. Melancholic depression was excluded from DSM as a distinct disorder owing to the impact of ageing, genetics, and course of illness. We challenge these assertions using retrospective data collected from patients with depression. Read More

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http://dx.doi.org/10.12809/eaap1884DOI Listing

Phospho-regulation of a conserved herpesvirus tegument protein by a virally-encoded protein kinase in viral pathogenicity and potential linkage between its evolution and viral phylogeny.

J Virol 2020 Jul 1. Epub 2020 Jul 1.

Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

Us3 proteins of herpes simplex virus 1 (HSV-1) and HSV-2 are multi-functional serine-threonine protein kinases. Here, we identified an HSV-2 tegument protein UL7 as a novel physiological substrate of HSV-2 Us3. Mutations in HSV-2 UL7, which precluded Us3 phosphorylation of the viral protein, significantly reduced mortality, viral replication in the vagina, and development of vaginal disease in mice following vaginal infection. Read More

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http://dx.doi.org/10.1128/JVI.01055-20DOI Listing

International prospective observational study investigating the disease course and heterogeneity of paediatric-onset inflammatory bowel disease: the protocol of the PIBD-SETQuality inception cohort study.

BMJ Open 2020 Jul 1;10(7):e035538. Epub 2020 Jul 1.

Department of Paediatric Gastroenterology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands

Introduction: Patients with paediatric-onset inflammatory bowel disease (PIBD) may develop a complicated disease course, including growth failure, bowel resection at young age and treatment-related adverse events, all of which can have significant and lasting effects on the patient's development and quality of life. Unfortunately, we are still not able to fully explain the heterogeneity between patients and their disease course and predict which patients will respond to certain therapies or are most at risk of developing a more complicated disease course. To investigate this, large prospective studies with long-term follow-up are needed. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-035538DOI Listing

Outcomes of a Rapid Adolescent Telehealth Scale-Up During the COVID-19 Pandemic.

J Adolesc Health 2020 Jun 28. Epub 2020 Jun 28.

Craig Dalsimer Division of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; PolicyLab, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Purpose: To describe the first 30 days of rapid adolescent telehealth scale-up in response to the coronavirus (COVID-19) pandemic at a single academic medical center and assess for disparities in visit completion rates by patient characteristics.

Methods: Visit outcome and patient demographic data were obtained via electronic health record (EHR) reports. Telehealth visit completion rates were compared by patient characteristics using the chi-square test and t-test. Read More

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http://dx.doi.org/10.1016/j.jadohealth.2020.05.025DOI Listing

Alteration of oral flora in betel quid chewers in Sri Lanka.

J Microbiol Immunol Infect 2020 Jun 27. Epub 2020 Jun 27.

Division of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan. Electronic address:

Background: Betel quid chewing is known as a crucial risk factor for oral diseases such as periodontal diseases, oral cancer, and precancerous lesions in Southeast Asian countries. Although abnormal oral bacterial flora may be linked to betel quid related-oral diseases such as oral cancer, precancerous lesions, and periodontal diseases, little information is available on alterations of their oral flora thus far. To identify these alterations, we analyzed the oral flora in betel quid chewers (BQC) and non-chewers (NC) in Sri Lanka. Read More

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http://dx.doi.org/10.1016/j.jmii.2020.06.009DOI Listing

Atrial functional mitral regurgitation: mechanisms and surgical implications.

Asian Cardiovasc Thorac Ann 2020 Jul 1:218492320941388. Epub 2020 Jul 1.

Division of Cardiology, Department of Medicine and Therapeutics, Laboratory of Cardiac Imaging and 3D Printing, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong.

The term atrial functional mitral regurgitation refers to a newly recognized disease entity in which mitral regurgitation occurs secondary to left atrial disease, without left ventricular dilatation and intrinsic mitral valve disease, typically in the setting of long-standing atrial fibrillation. Recent evidence suggests that atrial functional mitral regurgitation is associated with increased risk of death and heart failure re-hospitalization. The etiology, pathophysiology, and mechanism of atrial functional mitral regurgitation is not completely understood but they should not be regarded as the same as for the conventional type of functional mitral regurgitation secondary to left ventricular dilatation and dysfunction. Read More

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http://dx.doi.org/10.1177/0218492320941388DOI Listing

A case of non-cirrhotic portal hypertension related to azathioprine therapy in a patient with Crohn's disease.

Intest Res 2020 Jul 2. Epub 2020 Jul 2.

Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.

Azathioprine is widely used for the treatment of Crohn's disease (CD). Few cases from Western countries have reported idiopathic non-cirrhotic portal hypertension (NCPH) related to thiopurine therapy in patients with inflammatory bowel disease. Idiopathic NCPH is a rare hepatic condition with intrahepatic portal hypertension but no evidence of cirrhosis or chronic liver disease. Read More

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http://dx.doi.org/10.5217/ir.2020.00016DOI Listing

COVID 19: Diabetes and Obesity API-ICP Recommendations.

J Assoc Physicians India 2020 May;68(5):42-44

Consultant at Bhatia Hospital, Mumbai, Maharashtra.

Diabetes and Obesity are major risk factors which confer vulnerability to Covid 19 . Diabetes has immune defects which makes the individual susceptible to infections and covid 19 is no exception . Also covid 19 can cause pancreatic damage as well as stress hyperglycaemia in hospitals which may need Insulin . Read More

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A Systematic Review of Tobacco Industry Tactics in Southeast Asia: Lessons for Other Low- And MiddleIncome Regions.

Int J Health Policy Manag 2020 Jun 21. Epub 2020 Jun 21.

Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.

Background: Transnational tobacco companies (TTCs) have a well-established presence in Southeast Asia and are now targeting other low- and middle-income countries (LMICs), especially Africa. While the tobacco industry's tactics in Southeast Asia are well documented, no study has systematically reviewed these tactics to inform tobacco control policies and movements in Africa, where the tobacco epidemic is spreading.

Methods: We conducted a systematic literature review of articles that describe tobacco industry tactics in Southeast Asia, which includes Singapore, Indonesia, Malaysia, the Philippines, Myanmar, East Timor, Thailand, Cambodia, Vietnam, Laos, and Brunei. Read More

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http://dx.doi.org/10.34172/ijhpm.2020.97DOI Listing

Ageing in Asia: Beyond the Astana Declaration Towards Financing Long-term Care for All Comment on "Financing Long-term Care: Lessons From Japan".

Int J Health Policy Manag 2020 Feb 18. Epub 2020 Feb 18.

Graduate School of Public Policy, Nazarbayev Unversity, Nur-Sultan, Kazakhstan.

The Astana Declaration on primary healthcare in 2018 was the attempt to revive the ideals of the World Health Organization (WHO) Alma-Ata Declaration 40 years later, together with a call for the political will to provide adequate financing at acceptable quality of care. This approach is taken to achieve the past ideals of Health for All, given the new challenges of universal health coverage. The economic case for primary healthcare is justified against the growing demand due in part to the growing costs of chronic conditions and the rise of ageing population, other than the supply-side factors of the healthcare industry. Read More

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http://dx.doi.org/10.34172/ijhpm.2020.15DOI Listing
February 2020

COVID-19 Pandemic: What Can the West Learn From the East?

Int J Health Policy Manag 2020 May 31. Epub 2020 May 31.

Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.

Differences in public health approaches to control the coronavirus disease 2019 (COVID-19) pandemic could largely explain substantial variations in epidemiological indicators (such as incidence and mortality) between the West and the East. COVID-19 revealed vulnerabilities of most western countries' healthcare systems in their response to the ongoing public health crisis. Hence, western countries can possibly learn from practices from several East Asian countries regarding infrastructures, epidemiological surveillance and control strategies to mitigate the public health impact of the pandemic. Read More

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http://dx.doi.org/10.34172/ijhpm.2020.85DOI Listing

Preliminary efficacy of AWARE in college health service centers: A group psychotherapy intervention for Asian American women.

J Am Coll Health 2020 Jul 1:1-5. Epub 2020 Jul 1.

Departments of Pediatric Newborn Medicine & Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.

: Asian Women's Action for Resilience and Empowerment (AWARE) is a psychotherapy intervention designed to improve the mental health of Asian American women. This study documented the feasibility and preliminary efficacy of AWARE at three university health service centers in Massachusetts. : 174 female Asian American college/graduate students were screened, and 48 (64%) met the eligibility criteria and enrolled in the study. Read More

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http://dx.doi.org/10.1080/07448481.2020.1777135DOI Listing

Thoracic cancer surgery during the COVID-19 pandemic: A consensus statement from the Thoracic Domain of the Asian Society for Cardiovascular and Thoracic Surgery.

Asian Cardiovasc Thorac Ann 2020 Jul 1:218492320940162. Epub 2020 Jul 1.

Department of Thoracic Surgery, University of Tokyo Graduate School of Medicine, Tokyo, Japan.

Objectives: Healthcare resources have been mobilized to combat the COVID-19 pandemic of 2020. The Thoracic Domain of the Asian Society for Cardiovascular and Thoracic Surgery reports a consensus statement on the provision of thoracic cancer surgery during this pandemic.

Methods: A Thoracic Experts Panel was convened by the Society. Read More

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http://dx.doi.org/10.1177/0218492320940162DOI Listing

Analyzing China's contributions to major dermatologic journals from the past 20 years.

Dermatol Online J 2020 Mar 15;26(3). Epub 2020 Mar 15.

Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC.

Background: Over the past 20 years, China has experienced an increased popularity of Western medicine. The impact of Western medicine in China on the field of dermatology is not well characterized.

Objective: To assess the impact China has had on the field of dermatology by analyzing the total publications to six dermatological journals, compared to two other Asian countries: Japan and Korea. Read More

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Characteristics of patients with familial Mediterranean fever in Denmark: a retrospective nationwide register-based cohort study.

Scand J Rheumatol 2020 Jul 1:1-9. Epub 2020 Jul 1.

Department of Infectious Diseases, Odense University Hospital , Odense, Denmark.

Objectives: To investigate epidemiology, demography, and genetic and clinical characteristics of patients with familial Mediterranean fever (FMF) in Denmark.

Method: In this population-based, cross-sectional cohort study, we identified FMF patients from discharge diagnoses using ICD-10 codes in the Danish National Patient Register, and linked data from the Danish Civil Registration System and laboratory databases for results of gene variant screening.

Results: We identified 495 FMF patients (prevalence 1:11 680) with a median age of 29 years and a female ratio of 51%. Read More

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http://dx.doi.org/10.1080/03009742.2020.1756400DOI Listing

Mental Health Conditions in Young Asian Adults and Motivation to Seek Counseling: A Cross-Country Study.

Asia Pac J Public Health 2020 Jul 1:1010539520937091. Epub 2020 Jul 1.

Hong Kong Baptist University, Kowloon, Hong Kong.

Mental illness is a prevalent and pressing public health problem among the Asian population, especially among young adults. This study examined the psychosocial predictors of the intention to seek counseling based on the theory of planned behavior (TPB) and the effects of mental health conditions on the relative contributions of the TPB predictors in forming the intention among Asian young adults. The survey results in Singapore (n = 232) and Hong Kong (n = 998) revealed that attitudes, descriptive norms, and self-efficacy significantly predicted the intention to seek counseling in both Asian sites. Read More

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http://dx.doi.org/10.1177/1010539520937091DOI Listing