166,436 results match your criteria Asian Biomedicine [Journal]


Effect of model race and viewing perspective on body attractiveness and body size assessment in young Caucasian women: an eye-tracking study.

Psychol Res 2018 Dec 15. Epub 2018 Dec 15.

School of Psychology, University of Lincoln, Brayford Pool, Lincoln, LN6 7TS, UK.

Research has indicated that Caucasian women gaze more often at waist-hip and chest regions than other local body areas when assessing female body attractiveness and body size, and this stereotypical gaze distribution is further modulated by their own body satisfaction and body composition. However, little is known whether the model race and viewing perspective could affect women's body-viewing gaze behaviour and body perception. Here, we presented female body images of Caucasian, Asian and African avatars in a continuum of common dress sizes in full frontal, mid-profile and rear view, and asked young Caucasian women to rate the perceived body attractiveness and body size. Read More

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December 2018

Association Between Citrus Flushing Cycles and Asian Citrus Psyllid Demography in Huanglongbing-Free Area in Brazil.

Neotrop Entomol 2018 Dec 15. Epub 2018 Dec 15.

Agricultural Defense Agency of Bahia, Salvador, BA, Brasil.

Diaphorina citri Kuwayama (Hemiptera: Liviidae), named as Asian citrus psyllid (ACP), is the vector of the bacterium associated with huanglongbing (HLB), the most destructive citrus disease. The use of citrus flushing and ACP monitoring tools is essential for the knowledge of the occurrence pattern of cycles of both and for the improvement of the ACP management. During 3 years, 20 branches from 20 trees were evaluated for vegetative flushing, ACP abundance, and occupation in tree and branches in a Brazilian citrus area free for HLB. Read More

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December 2018

The Incidence and Risk Factors of Venous Thromboembolism in Patients with Inflammatory Bowel Disease: A Prospective Multicenter Cohort Study.

Digestion 2018 Dec 14:1-9. Epub 2018 Dec 14.

Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan.

Background: Venous thromboembolism (VTE) has been shown to be more frequent in inflammatory bowel disease (IBD) than in the general population in Western studies. However, the actual state of VTE in Asian IBD remains poorly understood.

Aims: To reveal the incidence of VTE in IBD patients in Japan. Read More

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December 2018

Questionnaire-Based Survey on Management of Ulcerative Colitis-Associated Cancer in East Asian Countries.

Digestion 2018 Dec 14;99(1):86-94. Epub 2018 Dec 14.

Sino United Health Clinic, Gopher Medical Center, Rui Jing Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background/aims: To elucidate the current management of ulcerative colitis (UC)-associated cancer, a questionnaire-based survey was conducted to gather current opinions on colitis-associated cancer in different East Asian countries.

Methods: The questionnaire, based on physicians, contains 9 questions focused on UC management and cancer surveillance. In addition, the questionnaire based on neoplastic cases, which contains 17 questions, was collected and analyzed. Read More

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December 2018

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems.

Chem Biol Interact 2018 Dec 13. Epub 2018 Dec 13.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia; Faculty of Science, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia.

Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD), infections and lung cancer. Even though there are various existing anti-inflammatory therapies, which are not enough to control the inflammation caused due to various contributing factors such as anti-inflammatory genes and antioxidant enzymes. This leads to an urgent need of novel drug delivery systems to combat the oxidative stress. Read More

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December 2018

Prevalence and clinical correlations of obsessive-compulsive symptoms in schizophrenia.

Asian J Psychiatr 2018 Nov 27;39:48-52. Epub 2018 Nov 27.

Department of Psychiatry, Centre of Excellence in Mental Health, PGIMER Dr RML Hospital, New Delhi, India. Electronic address:

Introduction: Obsessive compulsive symptoms are often present in persons with schizophrenia. Adequately powered studies to evaluate the effect of such symptoms in the course of the disorder, are few.

Aim: We aimed to estimate the prevalence and type of obsessive-compulsive symptoms in persons with schizophrenia. Read More

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November 2018

ARBOVIRUS INVESTIGATION IN PATIENTS FROM MATO GROSSO DURING ZIKA AND CHIKUNGUNYA VIRUS INTRODUTION IN BRAZIL, 2015-2016.

Acta Trop 2018 Dec 12. Epub 2018 Dec 12.

Programa de Pós-Graduação em Ciências da Saúde, Departamento de Ciências Básicas em Saúde, Faculdade de Medicina, Universidade Federal de Mato Grosso, Av. Fernando Correa da Costa, n. 2367, CCBS-I, sala 82, CEP 78060-900, Cuiabá, Mato Grosso, Brazil. Electronic address:

Arboviruses have become a major public health concern in Brazil, especially after Zika virus (ZIKV) and Chikungunya virus (CHIKV) introduction, leading to massive epidemics. We conducted an investigation of arboviruses in patients with acute febrile illness for less than five days in Mato Grosso state (MT) during the period of ZIKV and CHIKV dissemination in Brazil. To achieve that, 453 human serum samples of patients suspected of Dengue (DENV), Yellow Fever (YFV), ZIKV or CHIKV collected in health units of 31 cities of MT were subjected to RT-PCR protocols for 10 flaviviruses, 5 alphaviruses and orthobunyaviruses from Simbu serogroup, nucleotide sequencing and viral isolation. Read More

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December 2018
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Tobacco smoking, alcohol drinking, betel quid chewing, and the risk of head and neck cancer in an East Asian population.

Head Neck 2018 Dec 15. Epub 2018 Dec 15.

Division of Public Health, Department of Family and Preventive Medicine, and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah.

Background: The smoking prevalence among men in China is high, but the head and neck cancer incidence rates are low. This study's purpose was to investigate the impact of tobacco, betel quid, and alcohol on head and neck cancer risk in East Asia.

Methods: A multicenter case-control study (921 patients with head and neck cancer and 806 controls) in East Asia was conducted. Read More

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December 2018

The apparent low incidence of paediatric Type 2 diabetes in the Republic of Ireland is multifactorial.

Diabet Med 2018 Dec 15. Epub 2018 Dec 15.

Department of Paediatrics, Midland Regional Hospital, Mullingar, Co. Westmeath.

We read with interest the study by Candler et al. [1], evaluating the incidence of paediatric Type 2 diabetes mellitus in the UK and Republic of Ireland. They identified an overall incidence in UK children of 0. Read More

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December 2018

Selective mono-allylation of 1,3-diketones and their use in the synthesis of 3-allyl chromones and benzannulated 6,5-bicyclic ketals.

Chem Asian J 2018 Dec 14. Epub 2018 Dec 14.

University of Otago, Department of Chemistry, P.O. Box 56, 9054, Dunedin, NEW ZEALAND.

The selective mono-allylation of 1,3-diketone containing compounds is described. The reaction proceeds under mild reaction conditions and in moderate to high yield (66-99%). Using this procedure to access the key mono-allylated intermediate, the hitherto difficult to access, 3-allyl chromones were synthesized in excellent yield (87-98%). Read More

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December 2018

Role of a cotton endoreduplication-related gene, GaTOP6B, in response to drought stress.

Planta 2018 Dec 14. Epub 2018 Dec 14.

Zhengzhou Research Base, State Key Laboratory of Cotton Biology, Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.

Main Conclusion: Cotton GaTOP6B is involved in cellular endoreduplication and a positive response to drought stress via promoting plant leaf and root growth. Drought is deemed as one of adverse conditions that could cause substantial reductions in crop yields worldwide. Since cotton exhibits a moderate-tolerant phenotype under water-deficit conditions, the plant could therefore be used to characterize potential new genes regulating drought tolerance in crop plants. Read More

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December 2018
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Prevalence of Known Risk Factors for Type 2 Diabetes Mellitus in Multiethnic Urban Youth in Edmonton: Findings From the WHY ACT NOW Project.

Can J Diabetes 2018 Oct 9. Epub 2018 Oct 9.

Indigenous and Global Health Research Group, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

Objectives: The Canadian Diabetes Risk Assessment Questionnaire (CANRISK) is a validated, evidence-based, self-administered tool to assess the risk for type 2 diabetes mellitus in multiethnic Canadian adults. Identifying individuals at high risk for type 2 diabetes allows early intervention that improves modifiable risk factors. This study examined the risk factors for type 2 diabetes in multiethnic urban youth in Edmonton, Alberta. Read More

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October 2018

Impact of the Family Environment on Juvenile Mental Health: eSports Online Game Addiction and Delinquency.

Int J Environ Res Public Health 2018 Dec 13;15(12). Epub 2018 Dec 13.

Department of Sports Taekwondo, Graduate School of Physical Education, Kyung Hee University, Seocheon-dong 1, Giheung-gu, Yongin-si, Gyeonggi-do 17104, Korea.

Family types in Asian countries are rapidly changing as the society is changing. Thus, in this study, we analyzed and compared how the newly evolving family types (multicultural/dual-income) affect adolescents' online game addiction, delinquency, and online gaming (eSports) participation motivation. Multiple regression analysis was performed to examine the causal relationships between the variables, and multivariate analysis of variance and analysis of variance were performed for comparative analyses. Read More

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December 2018

A plastid phylogeny of the fern genus Arachniodes (Dryopteridaceae).

Mol Phylogenet Evol 2018 Dec 11. Epub 2018 Dec 11.

CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, P.O. Box 416, Chengdu, Sichuan 610041, China; Missouri Botanical Garden,4344 Shaw Blvd., St. Louis, Missouri 63110, U.S.A. Electronic address:

Arachniodes (Dryopteridaceae) is one of the most confusing and controversial fern genera in terms of its circumscription, nomenclature, and taxonomy. Estimates of species number range from 40 to 200. Previous molecular works included only 2-17 accessions representing 2-12 species of Arachniodes and allied genera, leaving most of the Asian species remain unsampled and the infragneric relationships unclear. Read More

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December 2018
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Predictor of Slower Gastric Emptying in Gastroesophageal Reflux Disease-Survey of An Asian-Pacific Cohort.

J Gastroenterol Hepatol 2018 Dec 14. Epub 2018 Dec 14.

Department of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Background: Asian populations have relatively lower prevalence of gastroesophageal reflux disease and tend to exhibit symptoms of prolonged gastric retention. However, it remains unknown if slower gastric empting influences its features in Asian countries.

Aim: We prospectively assessed the potential implications of slower gastric emptying in an Asian-Pacific cohort of gastroesophageal reflux disease by a hospital-based survey. Read More

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December 2018

Predictable Electronic Tuning By Choice of Azine Substituent in Five Iron(II) Triazoles: Redox Properties and DFT Calculations.

Chem Asian J 2018 Dec 14. Epub 2018 Dec 14.

University of Otago, Chemistry, Union Place West, 9054, Dunedin , NEW ZEALAND.

Five new mononuclear iron(II) tris-ligand complexes, and four solvatomorphs, have been made from the azine-substituted 1,2,4-triazole ligands (Lazine): [FeII(Lpyridazine)3](BF4)2 (1), [FeII(Lpyrazine)3](BF4)2 (2), [FeII(Lpyridine)3](BF4)2 (3), [FeII(L2pyrimidine)3](BF4)2 (4), and [FeII(L4pyrimidine)3](BF4)2 (5). Single-crystal XRD and solid-state magnetometry reveal that all of them are low spin (LS) Fe(II), except for solvatomorph 5·4H2O. Evans method NMR studies in CD2Cl2, (CD3)2CO and CD3CN show that all are LS in these solvents, except 5 in CD2Cl2 (consistent with L4pyrimidine imposing the weakest field). Read More

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December 2018

Evolutionary analysis of the Chikungunya virus epidemic in Mexico reveals intra-host mutational hotspots in the E1 protein.

PLoS One 2018 14;13(12):e0209292. Epub 2018 Dec 14.

División de Laboratorios de Vigilancia e Investigación Epidemiológica, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

The epidemic potential of Chikungunya virus (CHIKV) was recently made evident by its introduction and rapid expansion in the Caribbean and the Americas. We sought to gain a detailed understanding of the dynamics of the epidemic in Mexico, the country with the highest number of confirmed CHIKV cases in the Americas, and to characterise viral evolution at the population and intra-host level. Analysis of the spatiotemporal distribution of 2,739 diagnosed cases in Mexico from December 2014 to December 2015 showed a rapid nationwide expansion of the epidemic with focalisation in the South West of the country. Read More

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December 2018
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DRUSEN SUBTYPES AND CHOROIDAL CHARACTERISTICS IN ASIAN EYES WITH TYPICAL NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

Retina 2018 Dec 13. Epub 2018 Dec 13.

Department of Ophthalmology, Eye and ENT Hospital, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea.

Purpose: To investigate the prevalence of pachydrusen, soft drusen, and subretinal drusenoid deposits in eyes with different neovascular age-related macular degeneration (nAMD) subtypes, determine the relationship between each drusen type and the choroidal thickness, and analyze the distinct features of each nAMD subtype according to the drusen type.

Methods: Medical records involving 454 eyes from 454 patients with nAMD were retrospectively reviewed. The prevalence of each drusen type and the choroidal thickness and choroidal characteristics were evaluated according to the nAMD subtype. Read More

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December 2018
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Effect of Macrolide Prophylactic Therapy on AIDS-Defining Conditions and HIV-Associated Mortality.

J Acquir Immune Defic Syndr 2018 Dec 10. Epub 2018 Dec 10.

Research Institute for Tropical Medicine, Muntinlupa City, Philippines.

Background: Mycobacterium avium complex (MAC) prophylaxis is recommended for patients with advanced HIV infection. With the decrease in incidence of disseminated MAC infection and the availability of antiretroviral therapy (ART), the benefits of macrolide prophylaxis were investigated. This study examined the impact of macrolide prophylaxis on AIDS-defining conditions and HIV-associated mortality in a cohort of HIV-infected patients on ART. Read More

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December 2018

Association Between the Polymorphism in miR-605 and Cancer Susceptibility: a PRISMA-Compliant Meta-Analysis.

Clin Lab 2018 Oct;64(11)

Background: MicroRNAs (miRNAs) play important roles in cancer development. miR-605 was reported in several studies and showed potential as a prognostic biomarker. However, the association between miR-605 and the risk of cancer remained controversial in previous studies. Read More

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October 2018

Novel Calix[4]arene-based Bis-Nitric Oxide Complexes: Synthesis, Physical Properties and Structural Characterization.

Chem Asian J 2018 Dec 14. Epub 2018 Dec 14.

Marquette University, Chemistry, 535 N 14th St, 53233, Milwaukee, UNITED STATES.

Calix[4]arene-based molecules have proven to be excellent candidates for nitric oxide (NO) sensors and storage materials due to their unprecedented binding affinity for NO. However, the structure of calix[4]arene is complicated by the presence of four possible conformers: 1,3-alternate, 1,2-alternate, cone and partial cone (paco). While prior studies have established the structure of the complexes of NO with several of these conformers, the 1,2-alternate conformer complex, i. Read More

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December 2018

Luminescent Solar Concentrators Based on Renewable Polyester Matrices.

Chem Asian J 2018 Dec 14. Epub 2018 Dec 14.

Department of Chemistry and Industrial Chemistry, University of Pisa, Via Moruzzi 13, 56124, Pisa, Italy.

This study reports for the first time the use of bio-based alternatives for PMMA as host matrix for luminescent solar concentrators (LSCs). Notably, two types of renewable polyesters were synthesized in varying molar ratios via a two-step melt-polycondensation reaction with dibutyl tin oxide as catalyst. The first is a homopolymer of diethyl 2,3:4,5-di-O-methylene galactarate (GxMe) and isosorbide (IGPn), and the second is a random copolymer of GxMe with 1,3-propanediol and dimethyl terephthalate (GTPn). Read More

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December 2018

Entecavir and peginterferon alfa-2a in adults with HBeAg-positive immune tolerant chronic hepatitis B virus infection.

Hepatology 2018 Dec 14. Epub 2018 Dec 14.

University of Michigan.

Background/aim: Monotherapy with interferon or nucleoside analog is generally not recommended during the immune tolerant (IT) phase of chronic hepatitis B virus (HBV) infection. Recognition that high HBV DNA levels are associated with hepatocellular carcinoma has increased interest in treating HBV in the IT phase. Small pediatric studies reported efficacy with combination nucleoside analog and interferon therapy. Read More

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December 2018

Indocyanine green-enhanced fluorescence-guided video-assisted axillary surgery for chronic lymphocele.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Surgical Oncology, Unit of Surgical Oncology of the Esophagus and Digestive Tract, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.

Introduction: Lymphocele occurs frequently after regional lymph node dissection. Surgery with multiple lymphatic ligation represents the only reliable treatment for long-standing chronic lymphocele.

Materials And Surgical Technique: We report the case of a man with chronic axillary seroma after axillary lymphadenectomy for melanoma. Read More

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December 2018
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Effective method of gallbladder retraction for single-incision laparoscopic cholecystectomy.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

Introduction: Recently, single-incision laparoscopic cholecystectomy has been accepted as an alternative to conventional laparoscopic cholecystectomy. The aim of this study was to retrospectively evaluate the safety and feasibility of unique gallbladder retraction methods using an ENDOLOOP® (Ethicon, Tokyo, Japan) and Lapaherclosure™ (Hakko Medical, Tokyo, Japan).

Materials And Surgical Technique: From May 2013 to April 2015, 77 patients underwent single-incision laparoscopic cholecystectomy with this retraction technique. Read More

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December 2018

Combination of electrohydraulic lithotripsy and laparoscopy for gallbladder access in type III Mirizzi syndrome.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Division of Surgery, Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan.

Introduction: A 50-year-old Japanese man presented with obstructive jaundice. We performed endoscopic retrograde biliary drainage before biliary decompression. CT showed a thickened gallbladder wall with low-density areas and a 35-mm gallstone; the stone was impacted in the gallbladder neck and cystic duct. Read More

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December 2018

Laparoscopic reversal of Hartmann's procedure: A single-center experience.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Morphology, Experimental Medicine and Surgery, Section of General and Thoracic Surgery, University of Ferrara, Ferrara, Italy.

Introduction: Laparoscopic reversal of Hartmann's procedure (LHR) is considered a technically complex major surgical procedure. We present a retrospective analysis of a single-institution experience that assesses the treatment patterns and outcomes of patients who underwent LHR.

Materials And Surgical Technique: The study involved patients who underwent LHR between January 2004 and December 2017. Read More

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December 2018

Association of Asian mitochondrial DNA haplogroup B with new development of knee osteoarthritis in Koreans.

Int J Rheum Dis 2018 Dec 13. Epub 2018 Dec 13.

Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.

Aim: The aim of this study was to determine which mitochondrial DNA (mtDNA) haplogroup is associated with new development of knee osteoarthritis (OA).

Methods: Epidemiologic data and knee radiographs with the Kellgren-Lawrence (K/L) score of the Ansung cohort study were prospectively obtained from the 2nd (2005-2006) and 6th follow-up periods (2013-2014). The mtDNA was analyzed by multiplex mutagenetically separated polymerase chain reaction to determine Asian mtDNA haplogroups (M, G, D, D4, D5, M7, M8, M9, M10, N, A, N9, R, F and B). Read More

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December 2018
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Standardization of surgical procedures for laparoscopic Spiegel lobectomy: A single-institutional experience.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Second Department of Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan.

Introduction: Surgical techniques for Spiegel lobectomy remain technically difficult because of its deep anatomical location. Laparoscopic Spiegel lobectomy has not yet been standardized or widely reported. In the current study, we introduce technical improvements, including the liver hanging maneuver, to laparoscopic Spiegel lobectomy. Read More

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December 2018

Single-incision laparoscopy-assisted gastric transposition combined with thoracoscopic esophagectomy for esophageal replacement.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Pediatric Surgery, Ege University Faculty of Medicine, Izmir, Turkey.

Introduction: We present a novel approach to single-incision laparoscopy-assisted gastric transposition combined with thoracoscopic esophagectomy in a child with long-segment corrosive esophageal stricture (CES).

Materials And Surgical Technique: A 2.5-year-old boy with a history of caustic ingestion underwent periodic esophageal dilatations at 3-week intervals, four sessions of topical mitomycin C application, and a strict antacid/H antagonist therapy for 8 months. Read More

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December 2018

Fruitful first experience with an 8K ultra-high-definition endoscope for laparoscopic colorectal surgery.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Gastrointestinal Surgery, St. Luke's International Hospital, Tokyo, Japan.

We performed laparoscopic surgery for three cases of colorectal cancer using an 8K ultra-high-definition endoscopic system, which offers 16-fold higher resolution than the current 2K high-definition endoscope. The weight of the camera has been successfully reduced to 370 g. To maximize the advantages of the 8K ultra-high-definition endoscope, surgery was performed by darkening the room and placing a large 85-in. Read More

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December 2018

Safe and easy technique for the laparoscopic application of Seprafilm® in gynecologic surgery.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Obstetrics and Gynecology, School of Medicine, Keio University, Tokyo, Japan.

Introduction: Laparoscopic surgery is a minimally invasive surgery, and the rate of postoperative adhesions is low. Although Seprafilm® helps to reduce adhesions, its application in the abdominal cavity during laparoscopic surgery is difficult because of its material. Therefore, we propose an easy method for applying this adhesion barrier. Read More

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December 2018

Synchrotron X-ray imaging of a dichasium cupule of Castanopsis from Eocene Baltic amber.

Am J Bot 2018 Dec 13. Epub 2018 Dec 13.

Department of Palaeobiology, Swedish Museum of Natural History, Box 50007, 10405, Stockholm, Sweden.

Premise Of The Study: The Eocene Baltic amber deposit represents the largest accumulation of fossil resin worldwide, and hundreds of thousands of entrapped arthropods have been recovered. Although Baltic amber preserves delicate plant structures in high fidelity, angiosperms of the "Baltic amber forest" remain poorly studied. We describe a pistillate partial inflorescence of Castanopsis (Fagaceae), expanding the knowledge of Fagaceae diversity from Baltic amber. Read More

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December 2018
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Synthesis, Photophysical Properties and Two Photon Absorption Study of Tetraazachrysene-based N-heteroacenes.

Authors:
Qichun Zhang

Chem Asian J 2018 Dec 13. Epub 2018 Dec 13.

Nanyang Technological University, MSE, 50 Nanyang Ave, 639672, Singapore, SINGAPORE.

Three novel N-heteroacene molecules (SDNU-1, SDNU-2 and SDNU-3) based on tetraazachrysene units as cores have been designed, synthesized and fully characterized. Their photophysical, electrochemical and fluorescence properties were investigated, and they exhibited blue to green emission in solid state. Interestingly, SDNU-2 exhibited high solid photoluminescence quantum efficiencies (75. Read More

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December 2018
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Back to the Roots … and the Future!

Chem Asian J 2018 Dec 13. Epub 2018 Dec 13.

Chemistry - An Asian Journal, Weinheim, Germany.

Taking stock: Editor-in-Chief Theresa Kueckmann reflects on the roots of Chemistry - An Asian Journal and lays out how these connect to the plans ahead. Read More

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December 2018
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Far-Red/Near-Infrared Emissive (1,3-Dimethyl)barbituric Acid-Based AIEgens for High-Contrast Detection of Metastatic Tumors in Lung.

Chem Asian J 2018 Dec 13. Epub 2018 Dec 13.

Nankai University, College of Life Sciences, 94 Weijin Road, 300071, Tianjin, CHINA.

Despite of the enthusiastic research in aggregation-induced emission luminogens (AIEgens) in recent years, the ones that can be smoothly used for sophisticated biomedical applications such as in vivo bioimaging of pulmonary metastatic tumors during surgery are still limited. Herein, we report the design and synthesis of a new series of far-red/near-infrared (FR/NIR) fluorescent AIEgens that consist of methoxy-substituted tetraphenylethene (TPE) as the electron-donating moiety, (1,3-dimethyl)barbituric acid as the electron-withdrawing moiety, and different π-bridge units. As compared to benzene or 3,4-ethylenedioxythiophene, using thiophene as the π-conjugation unit between the donor and acceptor results in relatively higher absolute fluorescence quantum yield (14. Read More

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December 2018

Diet and Physical Activity of Korean Female Adolescents in Their Peer Networks.

J Nurs Scholarsh 2018 Dec 13. Epub 2018 Dec 13.

The University of Iowa, College of Nursing, Iowa City, IA, USA.

Purpose: The purpose of this study was to examine and compare the diet and physical activity behaviors of female adolescents and their friends within classroom-based peer networks in Korea.

Design: Complete social network analysis was used to examine the influence of classroom-based peers on adolescents' diets and physical activity. Data were collected by self-report from 99 female adolescents in three classrooms. Read More

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December 2018
2 Reads

Pediatric tinea capitis caused by Trichophyton violaceum and Trichophyton soudanense in Rochester, Minnesota, United States.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Mayo Clinic, Rochester, MN, USA.

Background: Tinea capitis is a common pediatric dermatophyte infection. Its main pathogen in the United States is Trichophyton tonsurans accounting for greater than 95% of the infections. Other pathogens including Trichophyton violaceum and Trichophyton soudanense are common in Africa. Read More

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December 2018
2 Reads

(Poly)terephthalates with Efficient Blue Emission in the Solid State.

Chem Asian J 2018 Dec 12. Epub 2018 Dec 12.

JAPAN.

We prepared dimethyl and diaryl 2,5-dialkoxytere-phthalates from dimethyl 2,5-dihydroxyterephthalate in good-to-high yields via alkylation or a sequence of alkylation, hydrolysis, chlorination, and condensation. The absorption spectra of the dialkoxyterephthalates contain a small band at 332-355 nm, which could be assigned to intramolecular charge-transfer transition from the alkoxy to alkoxycarbonyl groups on the basis of theoretical calculations using density functional theory. The dialkoxyterephthalates exhibited blue fluorescence with moderate-to-excellent quantum yields not only in solution but also in the solid state, such as a poly(methyl methacrylate) (PMMA) film and a powder. Read More

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December 2018

A Polystyrene-Cross-Linking Tricyclohexylphosphine: Synthesis, Characterization and Applications to Pd-Catalyzed Cross-Coupling Reactions of Aryl Chlorides.

Chem Asian J 2018 Dec 12. Epub 2018 Dec 12.

JAPAN.

A polystyrene-cross-linking tricyclohexylphosphine (PS-TCP) was synthesized through radical emulsion polymerization of 4-t-butylstyrene as a monomer and tris(trans-4-styrylcyclohexyl)phosphine as a three-fold cross-linker. The PS-TCP showed enhanced ligand performance compared to the corresponding polystyrene-triphenylphosphine hybrid PS-TPP and tricyclohexylphosphine in Pd-catalyzed Suzuki-Miyaura and Buchwald-Hartwig reactions of aryl chlorides. Read More

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December 2018

Useful technique for draining a large cystic tumor through the round ligament in laparoscopic left hemihepatectomy.

Asian J Endosc Surg 2018 Dec 12. Epub 2018 Dec 12.

Department of Gastroenterological Surgery, Fukuyama City Hospital, Fukuyama, Japan.

Introduction: Some cystic liver tumors are huge when the diagnosis is made or surgery is needed. Although reducing tumor size by preoperative aspiration or drainage of the contents of the cystic tumor is helpful for liver resection, such procedures have a risk of tumor dissemination.

Materials And Surgical Technique: After the round ligament was dissected, a 12-Fr drainage catheter was inserted into the tumor via the round ligament under ultrasonography. Read More

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December 2018

Clinical and molecular characteristics of bladder urothelial carcinoma subtypes.

J Cell Biochem 2018 Dec 12. Epub 2018 Dec 12.

Department of Organization, General Hospital of Benxi Iron and Steel Co., Benxi, China.

Bladder urothelial carcinoma (BLCA) is a common malignancy with high heterogeneity. A reasonable molecular subtyping can facilitate biological study and personalized therapy of BLCA. In this study, unsupervised consensus clustering was used to acquire the molecular subtypes of BLCA based on messenger RNA (mRNA) and microRNA (miRNA) data. Read More

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December 2018
2 Reads

Alkenylboronates: synthesis and applications.

Chem Asian J 2018 Dec 12. Epub 2018 Dec 12.

SPAIN.

Organoboron compounds have become one of the most versatile building blocks in organic synthesis due to their accesible and efficient conversion into many different functional groups. In particular, alkenylboronates have received much attention as very reactive substrates in Suzuki-Miyaura cross-coupling reactions. Accordingly, efforts towards the development of efficient methods to prepare this type of compounds are constant. Read More

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December 2018
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Three Dimensional Structures of NiO Nanoporous/ZnO Nanoarray Film for Enhanced Electrochromic Performance.

Chem Asian J 2018 Dec 12. Epub 2018 Dec 12.

Nanjing University of Posts and Telecommunications, Institute of Advanced materials, 9 Wenyuan Road, 210023, Nanjing, CHINA.

An electrochromic device using the as-obtained NiO nanoporous/ZnO nanoarray working electrode was constructed and assembled. NiO nanoporous/ZnO nanoarray film with three dimensional structures was prepared on ITO glass substrate by a two-step route which combined chemical bath deposition method with hydrothermal method. NiO nanoporous/ZnO nanoarray electrode reveals noticeable improvement of electrochromism compared to unitary NiO nanoporous, including larger optical modulation (81%), higher coloration efficiency (78. Read More

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December 2018

Effects of co-exposure of lipopolysaccharide and β-glucan (Zymosan A) in exacerbating murine allergic asthma associated with Asian sand dust.

J Appl Toxicol 2018 Dec 12. Epub 2018 Dec 12.

Environmental Chemistry Division, National Institute for Environmental Studies, Ibaraki, 305-8506, Japan.

During the 2000s, Asian sand dust (ASD) was implicated in the increasing prevalence of respiratory disorders, including asthma. We previously demonstrated that a fungus from ASD aerosol exacerbated ovalbumin (OVA)-induced airways inflammation. Exposure to heat-inactivated ASD (H-ASD) and either Zymosan A (ZymA, containing β-glucan) or lipopolysaccharide (LPS) exacerbated allergic airways inflammation in a mouse model, but the effects of co-exposure of LPS and β-glucan are unclear. Read More

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December 2018

Aromatic and Antiaromatic Cyclophane-type Hexaphyrin Dimers.

Authors:
Atsuhiro Osuka

Chem Asian J 2018 Dec 11. Epub 2018 Dec 11.

Kyoto University, Graduate School of Science, Department of Chemistry, Kita-shirakawa Oiwake-cho, Sakyo-ku, 606-8502, Kyoto, JAPAN.

A peripherally strapped [28]hexaphyrin takes a rectangular conformation and exhibits antiaromatic character. A cyclophane-type dimer consisting of such [28]hexaphyrins was synthesized from hexakis(pentafluorophenyl) [26]hexaphyrin via SNAr reaction with allyl alcohol, one-pot intra- and intermolecular olefin metathesis under improved Hoveyda-Grubbs catalysis, and final reduction with NaBH4. The cyclophane-type structures of [26]- and [28]hexaphyrin dimers have been revealed by X-ray analysis. Read More

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December 2018

A facile synthesis of thiophene-annulated naphthalene diimide-based small-molecular acceptors via two-step C-H activation.

Chem Asian J 2018 Dec 11. Epub 2018 Dec 11.

JAPAN.

Thiophene-annulated naphthalene diimide (NTI)-based molecules have recently emerged as an important class of n-type electronic materials. However, their synthesis has predominantly been achieved by Stille or Suzuki coupling reactions despite the presence of a potential C-H bond in NTI. Additionally, the synthesis of NTI or more generally mono-functionalization of naphthalene diimide (NDI) starts with a cumbersome bromination that has low yield, unselectivity, and tedious purification. Read More

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December 2018

Electronic Modulation of Palladium in Metal Phosphide Nanoparticles for Chemo-Selective Reduction of Halogenated Nitrobenzenes.

Chem Asian J 2018 Dec 11. Epub 2018 Dec 11.

CHINA.

Tuning the electronic property of transition metal plays an important role in the selective catalysis. Herein, the control synthesis of (PdxNiy)-P nanoparticles is reported. The binding energy of Pd3d5/2 as a function of x/y ratio are well tunable from 335. Read More

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December 2018

Predictive value of oncogenic driver subtype, programmed death-1 ligand (PD-L1) score, and smoking status on the efficacy of PD-1/PD-L1 inhibitors in patients with oncogene-driven non-small cell lung cancer.

Cancer 2018 Dec 11. Epub 2018 Dec 11.

Division of Medical Oncology, University of Colorado, Aurora, Colorado.

Background: This multicenter, retrospective study explored the value of oncogene driver subtype, programmed death-1 ligand (PD-L1) status, and smoking status for predicting which patients with oncogene-driven non-small cell lung cancer (NSCLC) would benefit from treatment with programmed death-1 (PD-1)/PD-L1 inhibitors.

Methods: The clinical features, PD-L1 tumor proportion scores, and PD-1/PD-L1 inhibitor (PDi) outcomes (objective response rate and progression-free survival) of patients who had advanced NSCLC with Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) mutations or common, actionable oncogenic drivers were captured.

Results: In total, 189 oncogene-positive patients were analyzed. Read More

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December 2018

Synthesis of Tetracoordinate Boron-Fused Benzoaceanthrylene Analogs via Tandem Electrophilic C-H Borylation.

Chem Asian J 2018 Dec 7. Epub 2018 Dec 7.

Kwansei Gakuin University, School of Science and Technology, Gakuen 2-1, 669-1337, Sanda, JAPAN.

Benzoaceanthrylene analogs with tetracoordinate boron at the ring junction were synthesized through tandem electrophilic C-H borylation of 2,6-dinaphthylpyridine followed by nucleophilic substitution. Notably, the [5,6]-annulation occurred selectively over [6,6]-annulation with the assistance of nitrogen coordination of the pyridine ring. The X-ray crystallographic analysis revealed the polycyclic skeleton with distorted tetracoordinate boron atom and the unique packing structure with intermolecular π-π interaction. Read More

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December 2018