4,577 results match your criteria Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists[Journal]


Comparative evaluation of cerebral gliomas using rCBV measurements during sequential acquisition of T1-perfusion and T2*-perfusion MRI.

PLoS One 2019 24;14(4):e0215400. Epub 2019 Apr 24.

Philips Health Tech Asia Pacific, Minato-ku Tokyo, Japan.

Objective: To assess the inter-technique agreement of relative cerebral blood volume (rCBV) measurements obtained using T1- and T2*-perfusion MRI on 3T scanner in glioma patients.

Methods: A total of 49 adult patients with gliomas underwent both on T1- and T2*-perfusion in the same scanning session, and rCBV maps were estimated using both methods. For the quantitative analysis; Two independent observers recorded the rCBV values from the tumor as well as contralateral brain tissue from both T1- and T2*-perfusion. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215400PLOS

Analysis of serum Haptoglobin using glycoproteomics and lectin immunoassay in liver diseases in Hepatitis B virus infection.

Clin Chim Acta 2019 Apr 20. Epub 2019 Apr 20.

Transfusion Transmitted Diseases Department, National Institute of Immunohaematology (ICMR), 13th Floor, New Multi-storeyed Bldg, KEM Hospital Campus, Parel, Mumbai 400 012, Maharashtra, India. Electronic address:

Background: Hepatocellular carcinoma (HCC) due to Hepatitis B viral (HBV) infection is major cause in Asia-Pacific countries. Its early detection is of paramount importance using a marker having both sensitivity and specificity. The present study promises diagnostic and prognostic markers by the identification of site specific glycoforms on Haptoglobin (Hp) using LC-MS/MS and lectin ELISA in liver diseased conditions in HBV infection. Read More

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http://dx.doi.org/10.1016/j.cca.2019.04.072DOI Listing

Clade-age-dependent diversification under high species turnover shapes species richness disparities among tropical rainforest lineages of Bulbophyllum (Orchidaceae).

BMC Evol Biol 2019 Apr 24;19(1):93. Epub 2019 Apr 24.

Department of Biosciences, University of Salzburg, Hellbrunnerstrasse 34, 5020, Salzburg, Austria.

Background: Tropical rainforests (TRFs) harbour almost half of the world's vascular plant species diversity while covering only about 6-7% of land. However, why species richness varies amongst the Earth's major TRF regions remains poorly understood. Here we investigate the evolutionary processes shaping continental species richness disparities of the pantropical, epiphytic and mostly TRF-dwelling orchid mega-genus Bulbophyllum (c. Read More

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http://dx.doi.org/10.1186/s12862-019-1416-1DOI Listing

Psychosocial Management Before, During, and After Emergencies and Disasters-Results from the Kobe Expert Meeting.

Int J Environ Res Public Health 2019 Apr 12;16(8). Epub 2019 Apr 12.

National Institute of Mental Health, National Center for Neurology and Psychiatry, Kodaira 187-0031, Japan.

Emergencies and disasters typically affect entire communities, cause substantial losses and disruption, and result in a significant and persistent mental health burden. There is currently a paucity of evidence on safe and effective individual- and community-level strategies for improving mental health before, during, and after such events. In October 2018, the World Health Organization (WHO) Centre for Health Development (WHO Kobe Centre) convened a meeting bringing together leading Asia Pacific and international disaster research experts. Read More

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http://dx.doi.org/10.3390/ijerph16081309DOI Listing

Consensus Statement on the Use of Bone Turnover Markers for Short-Term Monitoring of Osteoporosis Treatment in the Asia-Pacific Region.

J Clin Densitom 2019 Mar 20. Epub 2019 Mar 20.

Department of Orthopaedics, College of Medicine, National Taiwan University & Hospital, Taipei, Taiwan. Electronic address:

Osteoporosis is a major health issue. By 2050, a greater than 2-fold increase in patients number with hip fractures will occur in Asia representing 50% of all hip fractures worldwide. For the Asia-Pacific (AP) region, more efforts on controlling osteoporosis and the subsequent fractures are crucial. Read More

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http://dx.doi.org/10.1016/j.jocd.2019.03.004DOI Listing

Left atrial appendage closure with WATCHMAN in Asian patients: 2 year outcomes from the WASP registry.

Int J Cardiol Heart Vasc 2019 Jun 9;23:100358. Epub 2019 Apr 9.

National Heart Institute, Kuala Lumpur, Malaysia.

Background: Left atrial appendage closure is a non-pharmacological alternative for stroke prevention in high-risk non-valvular atrial fibrillation patients, but has not been widely studied in Asian patients. The prospective WASP registry assessed real-world outcomes for patients undergoing WATCHMAN implant in the Asia-Pacific region.

Methods: Data were collected from consecutive patients across 9 centres. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23529067193002
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http://dx.doi.org/10.1016/j.ijcha.2019.100358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458488PMC
June 2019
1 Read

Government pharmaceutical pricing strategies in the Asia-Pacific region: an overview.

J Mark Access Health Policy 2019 11;7(1):1601060. Epub 2019 Apr 11.

Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.

: Governments in Asia Pacific (APAC) are increasingly using pharmaceutical pricing strategies to contain rising healthcare costs. The objective of this narrative review is to discuss formal pricing strategies for reimbursed prescription medication in APAC, supported by relevant examples of implementation differences across countries. In the discussion section, we examine key advantages and disadvantages of each strategy. Read More

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http://dx.doi.org/10.1080/20016689.2019.1601060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461095PMC

Left atrial appendage closure device implantation guided with fluoroscopy only: Long-term results.

J Arrhythm 2019 Apr 4;35(2):262-266. Epub 2019 Feb 4.

Department of Cardiology and Vascular Medicine Faculty of Medicine Universitas Indonesia, and National Cardiovascular Center Harapan Kita Jakarta Indonesia.

Background: Left atrial appendage (LAA) closure device is an alternative to anticoagulants for stroke prevention in selected atrial fibrillation (AF) patients. The LAA device implantation is safe with short period of learning curve. The standard implantation technique warrants a transesophageal echocardiography (TEE) guided and general anesthesia. Read More

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http://dx.doi.org/10.1002/joa3.12151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457374PMC

The culture, mental health and psychosocial wellbeing of Rohingya refugees: a systematic review.

Epidemiol Psychiatr Sci 2019 Apr 22:1-6. Epub 2019 Apr 22.

Public Health Section, United Nations High Commissioner for Refugees,Geneva,Switzerland.

AimsDespite the magnitude and protracted nature of the Rohingya refugee situation, there is limited information on the culture, mental health and psychosocial wellbeing of this group. This paper, drawing on a report commissioned by the United Nations High Commissioner for Refugees (UNHCR), aims to provide a comprehensive synthesis of the literature on mental health and psychosocial wellbeing of Rohingya refugees, including an examination of associated cultural factors. The ultimate objective is to assist humanitarian actors and agencies in providing culturally relevant Mental Health and Psychosocial Support (MHPSS) for Rohingya refugees displaced to Bangladesh and other neighbouring countries. Read More

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http://dx.doi.org/10.1017/S2045796019000192DOI Listing
April 2019
1 Read

Comparative evaluation of novel screening strategies for colorectal cancer screening in China (TARGET-C): a study protocol for a multicentre randomised controlled trial.

BMJ Open 2019 Apr 20;9(4):e025935. Epub 2019 Apr 20.

Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Introduction: Screening for colorectal cancer (CRC) is effective in reducing the disease burden. However, high-level evidence from randomised controlled trials on the effectiveness of CRC screening modalities is still lacking. We will conduct a large-scale multicentre randomised controlled trial in China to evaluate the effectiveness and cost-effectiveness of different CRC screening strategies. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025935DOI Listing

APBioNet's annual International Conference on Bioinformatics (InCoB) returns to India in 2018.

BMC Genomics 2019 Apr 18;19(Suppl 9):266. Epub 2019 Apr 18.

Department of Molecular Sciences, Macquarie University, Sydney, NSW, 2109, Australia.

InCoB, one of the largest annual bioinformatics conferences in the Asia-Pacific region since its launch in 2002, returned to New Delhi, India after 12 years, with a conference attendance of 314 delegates. The 2018 conference had sessions on Big Data and Algorithms, Next Generation Sequencing and Omics Science, Structure, Function and Interactions, Disease and Drug Discovery and Plant and Agricultural Bioinformatics. The conference also featured an industry track as well as panel discussions on Women in Bioinformatics and Democratization vs. Read More

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http://dx.doi.org/10.1186/s12864-019-5582-8DOI Listing
April 2019
1 Read

"I'm Trying to Stop Things Before They Happen": Carers' Contributions to Patient Safety in Hospitals.

Qual Health Res 2019 Apr 19:1049732319841021. Epub 2019 Apr 19.

2 Australian Catholic University, Fitzroy, Victoria, Australia.

Patient safety policies increasingly encourage carer (i.e., family or friends) involvement in reducing health care-associated harm in hospital. Read More

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http://dx.doi.org/10.1177/1049732319841021DOI Listing
April 2019
3 Reads

Intraoperative colonoscopy in laparoscopic colorectal surgery: A review of recent publications.

Asian J Endosc Surg 2019 Apr 17. Epub 2019 Apr 17.

Department of Surgery, The University Hong Kong-Shenzhen Hospital, Shenzhen, China.

Introduction: Laparoscopic colorectal resection is becoming the gold standard for treating colorectal cancers because it offers superior short-term and comparable long-time outcomes compared to open surgery. Intraoperative colonoscopy (IOC) is increasingly performed for tumor localization and mucosal assessment. The aim of this report was to review the safety and efficacy of IOC in laparoscopic colorectal surgery. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ases.12704
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http://dx.doi.org/10.1111/ases.12704DOI Listing
April 2019
3 Reads

Dietary Patterns and Determinants of Changing Diets in Bangladesh from 1985 to 2010.

Curr Dev Nutr 2019 Apr 21;3(4):nzy091. Epub 2018 Nov 21.

Heidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.

Background: The government of Bangladesh has implemented multiple policies since 1971 to provide the population with more diverse and nutritious diets.

Objective: The aim of this study was to examine the drivers of dietary change over time and the roles agriculture and economic development have played.

Methods: We used principal component analysis to derive dietary patterns from 7 cross-sectional rounds of the Bangladesh Household [Income and] Expenditure Survey. Read More

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https://academic.oup.com/cdn/article/doi/10.1093/cdn/nzy091/
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http://dx.doi.org/10.1093/cdn/nzy091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459985PMC
April 2019
1 Read

Emerging respiratory infections threatening public health in the Asia-Pacific region: A position paper of the Asian Pacific Society of Respirology.

Respirology 2019 Apr 15. Epub 2019 Apr 15.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.

In past decades, we have seen several epidemics of respiratory infections from newly emerging viruses, most of which originated in animals. These emerging infections, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) and the pandemic influenza A(H1N1) and avian influenza (AI) viruses, have seriously threatened global health and the economy. In particular, MERS-CoV and AI A(H7N9) are still causing infections in several areas, and some clustering of cases of A(H5N1) and A(H7N9) may imply future possible pandemics. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13558
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http://dx.doi.org/10.1111/resp.13558DOI Listing
April 2019
2 Reads

Global, national, and urban burdens of paediatric asthma incidence attributable to ambient NO pollution: estimates from global datasets.

Lancet Planet Health 2019 Apr 10. Epub 2019 Apr 10.

Milken Institute School of Public Health, George Washington University, Washington, DC, USA. Electronic address:

Background: Paediatric asthma incidence is associated with exposure to traffic-related air pollution (TRAP), but the TRAP-attributable burden remains poorly quantified. Nitrogen dioxide (NO) is a major component and common proxy of TRAP. In this study, we estimated the annual global number of new paediatric asthma cases attributable to NO exposure at a resolution sufficient to resolve intra-urban exposure gradients. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S25425196193004
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http://dx.doi.org/10.1016/S2542-5196(19)30046-4DOI Listing
April 2019
4 Reads

Long-term loss to follow-up in the TREAT Asia HIV Observational Database (TAHOD).

HIV Med 2019 Apr 12. Epub 2019 Apr 12.

Faculty of Medicine, Udayana University & Sanglah Hospital, Bali, Indonesia.

Objectives: With earlier antiretroviral therapy (ART) initiation, time spent in HIV care is expected to increase. We aimed to investigate loss to follow-up (LTFU) in Asian patients who remained in care 5 years after ART initiation.

Methods: Long-term LTFU was defined as LTFU occurring after 5 years on ART. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/hiv.12734
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http://dx.doi.org/10.1111/hiv.12734DOI Listing
April 2019
2 Reads
3.988 Impact Factor

Identification of influenza C virus in young South Korean children, from October 2013 to September 2016.

J Clin Virol 2019 Mar 27;115:47-52. Epub 2019 Mar 27.

Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, South Korea; Asia Pacific Influenza Institute, Korea University College of Medicine, Seoul, South Korea. Electronic address:

Background: Influenza C virus has been largely neglected, compared to influenza A orB viruses, and is not routinely tested in clinical practices. However, several studies have indicated that influenza C virus causes severe acute respiratory illness and pneumonia in all ages.

Objective: We conducted a study to identify influenza C virus among young children in South Korea. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13866532193007
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http://dx.doi.org/10.1016/j.jcv.2019.03.016DOI Listing
March 2019
5 Reads

Immunogenicity and protection conferred by an optimized purified inactivated Zika vaccine in mice.

Vaccine 2019 Apr 6. Epub 2019 Apr 6.

Discovery Drive, Sanofi Pasteur Swiftwater, PA, USA.

After decades of inconsequential infections, and sporadic outbreaks in the Asia-Pacific region between 2007 and 2013, Zika virus caused a widespread epidemic in South America in 2015 that was complicated by severe congenital infections. After the WHO declared a Public Health Emergency of International Concern in February 2016, vaccine development efforts based on different platforms were initiated. Several candidates have since been evaluated in clinical phase I studies. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.04.013DOI Listing

Codon Usage Bias Analysis of : Higher Codon Adaptation to Host.

Viruses 2019 Apr 8;11(4). Epub 2019 Apr 8.

National Clonal Germplasm Repository for Citrus & Dates, United States Department of Agriculture-Agricultural Research Service, Riverside, CA 92507, USA.

(CTV), a member of the aphid-transmitted closterovirus group, is the causal agent of the notorious tristeza disease in several citrus species worldwide. The codon usage patterns of viruses reflect the evolutionary changes for optimization of their survival and adaptation in their fitness to the external environment and the hosts. The codon usage adaptation of CTV to specific citrus hosts remains to be studied; thus, its role in CTV evolution is not clearly comprehended. Read More

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https://www.mdpi.com/1999-4915/11/4/331
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http://dx.doi.org/10.3390/v11040331DOI Listing
April 2019
1 Read

Indication for treatment and severity of disease in treatment-naive patients with chronic hepatitis B virus infection.

Eur J Gastroenterol Hepatol 2019 Jun;31(6):723-728

Center for Infectiology.

Background And Aims: The prevalence of chronic hepatitis B virus (HBV) infection in Europe is poorly defined. Data on the proportion of patients eligible for therapy are lacking but are crucial to meet WHO elimination goals. The aims of our study were to provide an estimate of the need for antiviral treatment and to assess the prevalence of advanced liver disease in treatment-naive, chronic HBV-infected patients. Read More

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http://dx.doi.org/10.1097/MEG.0000000000001409DOI Listing
June 2019
1 Read

Knowledge and use of biosimilars in oncology: a survey by the European Society for Medical Oncology.

ESMO Open 2019 6;4(2):e000460. Epub 2019 Mar 6.

Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Background: Biosimilars can potentially improve the sustainability of cancer care; however, uptake is sometimes limited by safety concerns and a lack of understanding of the concept of extrapolation. The European Society for Medical Oncology (ESMO) conducted a survey to assess the current level of knowledge, understanding and comfort of use of biosimilars among prescribers specialised in oncology.

Methods: A 19-question survey was developed using the SurveyMonkey online platform (https://www. Read More

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http://dx.doi.org/10.1136/esmoopen-2018-000460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435239PMC

WHO Thematic Platform for Health Emergency and Disaster Risk Management Research Network (TPRN): Report of the Kobe Expert Meeting.

Int J Environ Res Public Health 2019 Apr 6;16(7). Epub 2019 Apr 6.

World Health Organization Centre for Health Development, Kobe 651-0073, Japan.

The WHO Thematic Platform for Health Emergency and Disaster Risk Management Research Network (TPRN) was established in 2016 in response to the Sendai Framework for Disaster Risk Reduction 2015⁻2030. The TPRN facilitates global collaborative action for improving the scientific evidence base in health emergency and disaster risk management (Health EDRM). In 2018, the WHO convened a meeting to identify key research questions, bringing together leading experts from WHO, TPRN, World Association for Disaster and Emergency Medicine (WADEM), and the Japan International Cooperation Agency, and delegates to the Asia Pacific Conference on Disaster Medicine (APCDM). Read More

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http://dx.doi.org/10.3390/ijerph16071232DOI Listing

Mutation of oppF gene in the Mycoplasma synoviae MS-H vaccine strain and its implication for differential serological responses to vaccination versus field challenge.

Vet Microbiol 2019 Apr 22;231:48-55. Epub 2019 Feb 22.

Asia Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary & Agricultural Sciences, The University of Melbourne, Werribee, Victoria, 3030, Australia.

Mycoplasma synoviae (MS) is a major pathogen of poultry globally, causing chronic respiratory disease and arthritis. Vaccination is an effective means for the control of the disease. The MS-H vaccine is an attenuated strain developed through chemical mutagenesis of an Australian field strain, 86079/7NS. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03781135183108
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http://dx.doi.org/10.1016/j.vetmic.2019.02.029DOI Listing
April 2019
3 Reads
2.511 Impact Factor

Genotyping Mycoplasma gallisepticum by multilocus sequence typing.

Vet Microbiol 2019 Apr 15;231:191-196. Epub 2019 Mar 15.

Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Hungária körút 21, Budapest 1143, Hungary; Department of Microbiology and Infectious Diseases, University of Veterinary Medicine, Hungária körút 23-25, Budapest 1143, Hungary. Electronic address:

Mycoplasma gallisepticum causes chronic respiratory disease and reproductive disorders in many bird species, resulting in considerable economic losses to the poultry industry. Maintenance of M. gallisepticum-free flocks is the most adequate method to control infection. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.03.016DOI Listing
April 2019
1 Read

Characterisation of the course of Mycoplasma bovis infection in naturally infected dairy herds.

Vet Microbiol 2019 Apr 9;231:107-115. Epub 2019 Mar 9.

Veterinary Bacteriology and Pathology, Research and Laboratory Division, Finnish Food Authority, Neulaniementie 4, 70210 Kuopio, Finland.

Mycoplasma bovis causes bovine respiratory disease, mastitis, arthritis and otitis. The importance of M. bovis has escalated because of recent outbreaks and introductions into countries previously free of M. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.03.007DOI Listing
April 2019
3 Reads

Clinical practice of diabetic pregnancy screening in Asia-Pacific Countries: a survey review.

Acta Diabetol 2019 Apr 6. Epub 2019 Apr 6.

Division of O&G, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.

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http://dx.doi.org/10.1007/s00592-019-01331-8DOI Listing
April 2019
1 Read

The practice patterns in the management of sebaceous carcinoma of the eyelid in the Asia Pacific region.

Eye (Lond) 2019 Apr 5. Epub 2019 Apr 5.

Department of Ophthalmology, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong SAR, China.

Purpose: To determine the practice patterns of ophthalmic plastic surgeons regarding the management of eyelid sebaceous carcinoma (SC).

Methods: An electronic survey was distributed to oculoplastic surgical colleagues in the Asia Pacific region requesting clinical information and treatment approaches to SC.

Results: The responses from 192 respondents from the Asia Pacific region was included and analyzed in this study. Read More

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http://dx.doi.org/10.1038/s41433-019-0432-0DOI Listing
April 2019
1 Read

Expression and significance of Th17 cells and related factors in patients with autoimmune hepatitis.

Authors:
Jihong An

Comb Chem High Throughput Screen 2019 Apr 2. Epub 2019 Apr 2.

Department of Infectious Diseases, Inner Mongolia People's Hospital, Inner Mongolia 010017. China.

Aim And Objective: This study aims to investigate the expression and clinical significance of Th17 cells and related factors in peripheral blood of patients with autoimmune hepatitis (AIH).

Materials And Methods: A retrospective selection of 100 patients with AIH were included as study group, and 100 healthy volunteers in the outpatient clinic were selected as the control group. The levels of IL-17, IL-6, IL-21 and TNF-α in peripheral blood of all subjects were detected by enzyme-linked immunosorbent assay and the frequency of Th17 cells and Treg cells was detected by flow cytometry. Read More

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http://dx.doi.org/10.2174/1386207322666190402160455DOI Listing
April 2019
3 Reads

Supporting the Management of Patients with Heart Failure within Asia-Pacific, Middle East, and African Countries: A Toolbox for Healthcare Providers.

Cardiology 2019 Apr 4;142 Suppl 1:1-10. Epub 2019 Apr 4.

Division of Cardiology, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Gauteng, South Africa.

Objectives: The management of heart failure (HF) is most effective when established treatment guidelines and recommendations are followed. We aimed to develop a "Toolbox" of resources to facilitate the care of patients with acute HF and chronic HF with reduced ejection fraction delivered by healthcare professionals across Asia-Pacific, the Middle East and Africa (henceforth referred to as the "Region").

Methods: We convened a group of cardiologists from across the Region to develop a set of checklists, algorithms, and other practical resources. Read More

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http://dx.doi.org/10.1159/000496663DOI Listing
April 2019
1 Read

From North American hegemony to global competition for scientific leadership? Insights from the Nobel population.

PLoS One 2019 3;14(4):e0213916. Epub 2019 Apr 3.

Institute of Sociology, University of Wuppertal, Wuppertal, Germany.

Based on the entire population of Nobel laureates in science from 1901 to 2017, we show that North America's rise as global power in science started in the 1920s. Following a transition period (1940s to 1960s), its scientific hegemony was consolidated in the 1970s. Yet since the 2000s, North America's global leadership in science has come under pressure. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213916PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447154PMC

Systematic review and survey of Neisseria gonorrhoeae ceftriaxone and azithromycin susceptibility data in the Asia Pacific, 2011 to 2016.

PLoS One 2019 3;14(4):e0213312. Epub 2019 Apr 3.

WHO Collaborating Centre for Sexually Transmitted Infections and Antimicrobial Resistance, New South Wales Health Pathology, Microbiology, Prince of Wales Hospital, Randwick, New South Wales, Australia.

Background: Antimicrobial resistance in Neisseria gonorrhoeae is a global concern, with the ongoing emergence of ceftriaxone and azithromycin resistance threatening current treatment paradigms. To monitor the emergence of antimicrobial resistance in N. gonorrhoeae, the World Health Organization (WHO) Gonococcal Antimicrobial Surveillance Programme (GASP) has operated in the Western Pacific and South East Asian regions since 1992. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213312PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447224PMC
April 2019
1 Read

Integrative settings approach to workplace health promotion to address contemporary challenges for worker health in the Asia-Pacific.

Glob Health Promot 2019 Apr 3:1757975918816691. Epub 2019 Apr 3.

1. Centre for Environment and Population Health, Griffith University, Brisbane, Australia.

Workplaces in the rapidly industrializing Asia-Pacific region face growing pressures from high-speed development driven by global competition, migration and the aging of the workforce. Apart from addressing work-related injuries, workplaces in the region also have to deal with increasing occupational stress, chronic diseases and their associated socio-economic burden. Meanwhile, interventions in workplace health are still dominated by a narrow behavioral change model. Read More

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http://dx.doi.org/10.1177/1757975918816691DOI Listing
April 2019
2 Reads

Practice Patterns in Parathyroid Surgery: A Survey of Asia-Pacific Parathyroid Surgeons.

World J Surg 2019 Apr 2. Epub 2019 Apr 2.

Endocrine Surgery Unit, Department of Surgery, The Royal Melbourne Hospital, Epworth Freemason's Hospital, Melbourne University, 300 Grattan Street, Parkville, VIC, 3050, Australia.

Background: Practice variations exist amongst parathyroid surgeons depending on their expertise and resources. Our study aims to elucidate the choice of surgical techniques and adjuncts used in parathyroid surgery by surgeons in the Asia-Pacific region.

Methods: A 25-question online survey was sent to members of five endocrine surgery associations. Read More

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http://dx.doi.org/10.1007/s00268-019-04990-4DOI Listing
April 2019
3 Reads

Female genital cutting in Malaysia: a mixed-methods study.

BMJ Open 2019 Apr 1;9(4):e025078. Epub 2019 Apr 1.

College of Asia Pacific Studies, Ritsumeikan Asia Pacific University, Beppu, Japan.

Objective: This study aimed to understand the reasons for the practice by the Muslim community, traditional practitioners and the views of religious scholars as well as the medicalisation trend of the practice of female genital cutting (FGC).

Design: This is a mixed-method (qualitative and quantitative) study. A questionnaire was created and used by three trained research assistants for the quantitative component of the study. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025078DOI Listing
April 2019
3 Reads

Scrub typhus (Tsutsugamushi disease) in a patient presenting with hemophagocytic syndrome.

Immunol Med 2018 Jun 17;41(2):82-84. Epub 2018 Aug 17.

a Department of Rheumatology , Kawasaki Medical School , Kurashiki , Japan.

Scrub typhus is a mite-borne infectious disease caused by Orientia tsutsugamushi, which is found mainly in East and Southeast Asia and in Australia. The disease presents with a variety of non-specific symptoms, including fever, headache, cough, myalgia, and rash. Delay in starting appropriate antimicrobial therapy may lead to serious complications and even death. Read More

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http://dx.doi.org/10.1080/13497413.2018.1481581DOI Listing
June 2018
2 Reads

A Multinational Comparison of Anti-Vascular Endothelial Growth Factor Use: The United States, the United Kingdom, and Asia-Pacific.

Ophthalmol Retina 2019 Jan 9;3(1):16-26. Epub 2018 Aug 9.

Department of Ophthalmology, New York University School of Medicine, New York, New York.

Purpose: A comparison of anti-vascular endothelial growth factor (anti-VEGF) medication use across multiple countries.

Clinical Relevance: Anti-VEGF medication use is now considered first-line treatment for numerous retinal diseases globally. Exploring medication choices, costs within each healthcare system, policy challenges, emerging treatments, and patient access all provide insight into a newly recognized and major public health issue. Read More

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http://dx.doi.org/10.1016/j.oret.2018.08.002DOI Listing
January 2019
2 Reads

Enhancing Omega-3 Long-Chain Polyunsaturated Fatty Acid Content of Dairy-Derived Foods for Human Consumption.

Nutrients 2019 Mar 29;11(4). Epub 2019 Mar 29.

Animal Genetics and Nutrition, Veterinary Sciences Discipline, College of Public Health, Medical and Veterinary Sciences, Division of Tropical Health and Medicine, James Cook University, Townsville QLD 4811, Australia.

Omega-3 polyunsaturated fatty acids ( PUFA) are termed essential fatty acids because they cannot be synthesized by humans due to the lack of delta-12 and delta-15 desaturase enzymes and must therefore be acquired from the diet. PUFA include α-linolenic acid (ALA, 18:3n-3), eicosapentaenoic (EPA, 20:5n-3), docosahexaenoic (DHA, 22:6n-3), and the less recognized docosapentaenoic acid (DPA, 22:5n-3). The three long-chain (≥C) PUFA (n-3 LC-PUFA), EPA, DHA, and DPA play an important role in human health by reducing the risk of chronic diseases. Read More

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http://dx.doi.org/10.3390/nu11040743DOI Listing
March 2019
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Clinical and Epidemiological Patterns of Scrub Typhus, an Emerging Disease in Bhutan.

Trop Med Infect Dis 2019 Mar 29;4(2). Epub 2019 Mar 29.

School of Veterinary Science, Massey University, Palmerston North 4442, New Zealand.

Scrub typhus (ST) is a vector-borne rickettsial infection causing acute febrile illness. The re-emergence of ST in the Asia-Pacific region represents a serious public health threat. ST was first detected in Bhutan in 2008. Read More

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http://dx.doi.org/10.3390/tropicalmed4020056DOI Listing
March 2019
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Network inference in stochastic systems from neurons to currencies: Improved performance at small sample size.

Phys Rev E 2019 Feb;99(2-1):023311

School of Computational Sciences, Korea Institute for Advanced Study, Seoul 02455, Korea.

The fundamental problem in modeling complex phenomena such as human perception using probabilistic methods is that of deducing a stochastic model of interactions between the constituents of a system from observed configurations. Even in this era of big data, the complexity of the systems being modeled implies that inference methods must be effective in the difficult regimes of small sample sizes and large coupling variability. Thus, model inference by means of minimization of a cost function requires additional assumptions such as sparsity of interactions to avoid overfitting. Read More

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http://dx.doi.org/10.1103/PhysRevE.99.023311DOI Listing
February 2019
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Risk assessment for the sustainability of coastal communities: A preliminary study.

Sci Total Environ 2019 Mar 26;671:339-350. Epub 2019 Mar 26.

Guy Carpenter Asia-Pacific Climate Impact Centre, School of Energy and Environment, City University of Hong Kong, Hong Kong Special Administrative Region.

With communities increasingly concentrated in coastal regions globally, governments and stakeholders call for cohesive risk assessments for future sustainability in the wake of natural hazards. This can only be achieved through risk-based decision-making and smart resources treatment. To provide a basis for such actions, we here propose a risk assessment (RA) framework focusing on the risk-resilience-sustainability nexus. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.03.326DOI Listing

Assessing for Mood and Anxiety Disorders in Parents of Clinically-Referred Children: Laying the Foundation for a Family-Based Approach to Mental Health in Singapore.

Ann Acad Med Singapore 2019 Feb;48(2):55-62

Duke-NUS Medical School, Singapore.

Introduction: Family history of psychopathology is a risk factor for mood and anxiety disorders in children, but little is known about rates of parental psychopathology among treatment-seeking youth with affective disorders in the Asia Pacific region. This study examined patterns of emotional and behavioural problems in parents of clinically-referred youth in Singapore. We hypothesised that parents would have higher rates of affective disorders compared to the Singapore national prevalence rate of 12%. Read More

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February 2019
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Asia Pacific survey of physicians on asthma and allergic rhinitis (ASPAIR): data from China.

Chin Med J (Engl) 2019 Mar 27. Epub 2019 Mar 27.

Real World Evidence and Epidemiology, GSK, 139234, Singapore.

Background: In China, the prevalence of allergic rhinitis (AR) and asthma has increased in the past decade. As these two diseases frequently coexist, the Asia-Pacific Survey of Physicians on Asthma and Allergic Rhinitis (ASPAIR) study aimed to assess physicians' beliefs and treatment patterns of coexistent asthma-AR across six Asian countries. This analysis presented the results from China. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000229DOI Listing
March 2019
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Asia-Pacific Countries Moving Toward Universal Health Coverage.

Health Syst Reform 2019 ;5(1):1-6

a Department of Public Health , La Trobe University , Melbourne , Australia.

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http://dx.doi.org/10.1080/23288604.2018.1543537DOI Listing
January 2019

Governance Functions to Accelerate Progress toward Universal Health Coverage (UHC) in the Asia-Pacific Region.

Health Syst Reform 2019 ;5(1):48-58

b Our Hong Kong Foundation , Hong Kong , China.

Many countries in the Asia-Pacific region have committed to universal health coverage (UHC), which is reflected in both their political commitment and the governance actions they have taken in steering their health systems toward the goals of universal access to care and protection from financial hardship. Countries throughout the region are at different stages of development and have different political and governance contexts, which in turn shape how they pursue governance for UHC. This article reviews the governance functions deployed in the Asia-Pacific and finds that, in many, governance reforms adapting their health systems toward greater regulation, accountability, oversight, and stewardship of the health system have been part of their wider move toward UHC. Read More

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http://dx.doi.org/10.1080/23288604.2018.1543521DOI Listing
January 2019

Integration of Primary Care with Hospital Services for Sustainable Universal Health Coverage in Singapore.

Health Syst Reform 2019 ;5(1):18-23

b Saw Swee Hock School of Public Health , National University of Singapore , Singapore.

Primary care services have been developed and extended, with the support of the Singapore government, in order to address the increasing needs of the aging population and noncommunicable diseases and to achieve the goal of universal health care. Though countries across the Asia Pacific aspire to achieve universal coverage, there is no set pathway. In Singapore, various service models, quality assurance methods, and financing mechanisms have been piloted and some have been scaled up. Read More

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http://dx.doi.org/10.1080/23288604.2018.1543830DOI Listing
January 2019

Cotrimoxazole prophylaxis decreases tuberculosis risk among Asian patients with HIV.

J Int AIDS Soc 2019 Mar;22(3):e25264

Division of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Introduction: Cotrimoxazole (CTX) is recommended as prophylaxis against Pneumocystis jiroveci pneumonia, malaria and other serious bacterial infections in HIV-infected patients. Despite its in vitro activity against Mycobacterium tuberculosis, the effects of CTX preventive therapy on tuberculosis (TB) remain unclear.

Methods: Adults living with HIV enrolled in a regional observational cohort in Asia who had initiated combination antiretroviral therapy (cART) were included in the analysis. Read More

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http://dx.doi.org/10.1002/jia2.25264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439318PMC
March 2019
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