806,886 results match your criteria Asia Pacific Law Review[Journal]


Patterns of outdoor exposure to heat in three South Asian cities.

Sci Total Environ 2019 Apr 9;674:264-278. Epub 2019 Apr 9.

Wageningen University and Research, Wageningen Environmental Research, Wageningen, the Netherlands; London School of Economics and Political Science, Grantham Research Institute, London, United Kingdom.

Low socio-economic status has been widely recognized as a significant factor in enhancing a person's vulnerability to climate change including vulnerability to changes in temperature. Yet, little is known about exposure to heat within cities in developing countries, and even less about exposure within informal neighbourhoods in those countries. This paper presents an assessment of exposure to outdoor heat in the South Asian cities Delhi, Dhaka, and Faisalabad. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.04.087DOI Listing

Spatial-temporal variations and source contributions to forest ozone exposure in China.

Sci Total Environ 2019 Apr 9;674:189-199. Epub 2019 Apr 9.

Zachry Department of Civil Engineering, Texas A&M University, College Station, TX 77843, USA. Electronic address:

As surface ozone (O) concentrations have significantly increased in many regions of China, it is concerned that O may cause negative impacts on forests in the country. To estimate the risks of O exposure to forest health, several frequently used O exposure indices (M7, M24, N100, SUM60, W126, and AOT40f) were calculated for the entire year of 2013 and the source contributions to exposure in April and August were quantified using a source-oriented version of the Community Multiscale Air Quality (CMAQ) model. Critical loads for natural ecosystems (12 ppm-h for SUM60) and for moderately sensitive plant species (23. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.04.106DOI Listing
April 2019
2 Reads

Five-year observation of aerosol optical properties and its radiative effects to planetary boundary layer during air pollution episodes in North China: Intercomparison of a plain site and a mountainous site in Beijing.

Sci Total Environ 2019 Mar 31;674:140-158. Epub 2019 Mar 31.

State Key Laboratory of Severe Weather (LASW) and Institute of Atmospheric Composition, Chinese Academy of Meteorological Sciences, CMA, Beijing 100081, China.

The aerosol microphysical, optical and radiative properties of the whole column and upper planetary boundary layer (PBL) were investigated during 2013 to 2018 based on long-term sun-photometer observations at a surface site (~106 m a.s.l. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.03.418DOI Listing

Modificated Mahuang-Tang, a traditional herbal medicine suppresses inflammatory responses induced by cigarette smoke in human airway epithelial cell and mice.

Phytomedicine 2018 Dec 1;59:152777. Epub 2018 Dec 1.

College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757, Republic of Korea. Electronic address:

Background: Cigarette smoke (CS) is a major contributor to the high incidence of chronic obstructive pulmonary disease (COPD) featured as chronic inflammation and airway obstruction. Mahuang-Tang is a traditional polyherbal mixture composed of four different herbs. It is widely used in Asia as a remedy for allergic reaction and inflammation. Read More

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http://dx.doi.org/10.1016/j.phymed.2018.11.037DOI Listing
December 2018

Cytotoxic polyphenolic compounds from Lespedeza bicolor stem bark.

Fitoterapia 2019 Apr 17. Epub 2019 Apr 17.

G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, Vladivostok, 690022, Russia.

Four new pterocarpans (6aR,11aR)-6a,11a-dihydrolespedezol A (2), (6aR,11aR)-2-isoprenyl-6a,11a-dihydrolespedezol A (3), (6aR,11aR,3'R)-6a,11a-dihydrolespedezol A (4), (6aR,11aR,3'S)-6a,11a-dihydrolespedezol A (5) and one new stilbenoid with 1,2-diketone fragment named bicoloketone (6) along with one previously known pterocarpen lespedezol A (1) have been isolated from Lespedeza bicolor stem bark using multistage column chromatography on polyamide and silica gel. The structures of the isolated polyphenolic compounds were determined by spectroscopic methods. The absolute configurations of 4 and 5 were determined by comparison of their electronic circular dichroism (ECD) spectra obtained experimentally and the spectra calculated using time-dependent density functional theory (TDDFT). Read More

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http://dx.doi.org/10.1016/j.fitote.2019.04.003DOI Listing

Carrier frequency of spinal muscular atrophy in Thailand.

Neurol Sci 2019 Apr 19. Epub 2019 Apr 19.

Department of Internal Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Spinal muscular atrophy (SMA) is one of the leading causes of death in infants and young children from heritable diseases. Patients diagnosed with SMA develop symmetrical progressive muscle weakness and atrophy from degeneration of alpha motor neurons. Approximately 95% of patients have a homozygous deletion of survival motor neuron 1 (SMN1) gene in exon 7 and inherited in autosomal recessive pattern. Read More

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http://link.springer.com/10.1007/s10072-019-03885-5
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http://dx.doi.org/10.1007/s10072-019-03885-5DOI Listing
April 2019
1 Read

International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.

EBioMedicine 2019 Apr 16. Epub 2019 Apr 16.

Parasites and microbes, Wellcome Sanger Institute, Hinxton, UK.

Background: Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiotic resistance and invasiveness, in the context of genetic background.

Methods: Our dataset of 13,454 genomes, combined with four published genomic datasets, represented Africa (40%), Asia (25%), Europe (19%), North America (12%), and South America (5%). Read More

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http://dx.doi.org/10.1016/j.ebiom.2019.04.021DOI Listing

The impact of sex on risk of cardiovascular disease and all-cause mortality in adults with or without diabetes mellitus: A comparison between the U.S. and Japan.

J Diabetes Complications 2019 Apr 1. Epub 2019 Apr 1.

Department of Public Health, Shiga University of Medical Science, Otsu, Shiga, Japan; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Shiga, Japan.

Aims: To test a hypothesis that women with diabetes mellitus (DM) versus those without DM had a significantly higher risk of heart disease (HD), stroke and all-cause mortality than their male counterparts in the U.S. as well as in Japan. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10568727183131
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http://dx.doi.org/10.1016/j.jdiacomp.2019.03.008DOI Listing
April 2019
1 Read

Longitudinal magnetic resonance imaging changes in Japanese encephalitis.

Brain Dev 2019 Apr 16. Epub 2019 Apr 16.

Department of Pediatrics, Asahi General Hospital, Chiba, Japan.

Background: Japanese encephalitis is a flavivirus that can cause pandemic encephalitis, and is prevalent in Southeast Asia and Australia. Brain images of patients with Japanese encephalitis are characterized by thalamic lesions, distinct from those seen in viral encephalopathies caused by the herpes simplex virus and West Nile virus.

Aim: Herein, we describe for the first time a time-dependent magnetic resonance imaging pattern in Japanese encephalitis in a 10-month-old Japanese boy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03877604183056
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http://dx.doi.org/10.1016/j.braindev.2019.04.005DOI Listing
April 2019
1 Read

Coastal ecosystem in East Asia: Pollution and management.

Environ Pollut 2019 Apr 6. Epub 2019 Apr 6.

Chinese Academy of Sciences, China.

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https://linkinghub.elsevier.com/retrieve/pii/S02697491193174
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http://dx.doi.org/10.1016/j.envpol.2019.04.015DOI Listing
April 2019
1 Read

Computerized intervention to prevent drug use among at-risk adolescents in Central Asia: Preliminary family-level findings from a pilot mixed methods trial.

Int J Drug Policy 2019 Apr 16;68:75-85. Epub 2019 Apr 16.

Global Health Research Center of Central Asia (GHRCCA), Almaty, Kazakhstan.

Background: The rapidly growing rates of HIV infection in Kazakhstan are largely driven by injection drug use. The study adapts a family-focused evidence-based HIV and substance use prevention intervention for at-risk adolescents from communities in Almaty that have been greatly affected by heroin trade and use.

Methods: This NIDA-funded pilot feasibility trial included 181 at-risk adolescents (ages 14-17) recruited through local schools and 181 of their parents or other adult family members. Read More

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http://dx.doi.org/10.1016/j.drugpo.2019.03.022DOI Listing

Psychological Distress among Adolescents in Laos, Mongolia, Nepal, and Sri Lanka.

Asian Nurs Res (Korean Soc Nurs Sci) 2019 Apr 16. Epub 2019 Apr 16.

Hanyang University, College of Medicine, Department of Preventive Medicine; Hanyang University, Institute for Health and Society, Seoul, Republic of Korea.

Purpose: The purpose of this study was to explore psychological distress and examine the relationship between this distress and individual, family, and school factors among adolescents in four low- and middle-income countries (LAMICs) in Asia (i.e., Laos, Mongolia, Nepal, and Sri Lanka). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19761317183023
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http://dx.doi.org/10.1016/j.anr.2019.04.001DOI Listing
April 2019
1 Read

Association between excessive supraventricular ectopy and subclinical cerebrovascular disease: A population-based study.

Eur J Neurol 2019 Apr 19. Epub 2019 Apr 19.

Department of Public Health, Shiga University of Medical Science, Otsu, Japan.

Background: The association between an increased supraventricular ectopic beat (SVEB) and subclinical cerebrovascular disease remains unclear. Given the emerging concept that an increased SVEB is a marker of atrial cardiomyopathy or atherosclerosis burden, we sought to determine whether excessive supraventricular ectopic activity (ESVEA) is associated with a higher burden of subclinical cerebrovascular disease in the middle-aged to older cohort with neither apparent stroke nor atrial fibrillation.

Methods: We conducted a cross-sectional population-based study of 462 men (mean age, 68. Read More

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http://dx.doi.org/10.1111/ene.13970DOI Listing

Association of Diabetes With All-Cause and Cause-Specific Mortality in Asia: A Pooled Analysis of More Than 1 Million Participants.

JAMA Netw Open 2019 Apr 5;2(4):e192696. Epub 2019 Apr 5.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

Importance: Asia is home to the largest diabetic populations in the world. However, limited studies have quantified the association of diabetes with all-cause and cause-specific mortality in Asian populations.

Objectives: To evaluate the association of diabetes with all-cause and cause-specific mortality in Asia and to investigate potential effect modifications of the diabetes-mortality associations by participants' age, sex, education level, body mass index, and smoking status. Read More

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2019.2696DOI Listing
April 2019
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Outcomes of Bedaquiline Treatment in Patients with Multidrug-Resistant Tuberculosis.

Emerg Infect Dis 2019 May;25(5):936-943

Bedaquiline is recommended by the World Health Organization for the treatment of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). We pooled data from 5 cohorts of patients treated with bedaquiline in France, Georgia, Armenia, and South Africa and in a multicountry study. The rate of culture conversion to negative at 6 months (by the end of 6 months of treatment) was 78% (95% CI 73. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1823_article.htm
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http://dx.doi.org/10.3201/eid2505.181823DOI Listing
May 2019
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Severe Myasthenic Manifestation of Leptospirosis Associated with New Sequence Type of Leptospira interrogans.

Emerg Infect Dis 2019 May;25(5):968-971

We report the rapid development of a myasthenic crisis as the first-time manifestation of myasthenia gravis. The symptoms developed in the course of acute leptospirosis associated with a new sequence type of Leptospira interrogans. Antibiotic treatment led to rapid amelioration of myasthenia. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1591_article.htm
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http://dx.doi.org/10.3201/eid2505.181591DOI Listing
May 2019
1 Read

Southeast Asia Strategic Multilateral Dialogue on Biosecurity.

Emerg Infect Dis 2019 May;25(5)

A strategic multilateral dialogue related to biosecurity risks in Southeast Asia, established in 2014, now includes participants from Singapore, Malaysia, Indonesia, Thailand, Philippines, and the United States. This dialogue is conducted at the nonministerial level, enabling participants to engage without the constraints of operating in their official capacities. Participants reflect on mechanisms to detect, mitigate, and respond to biosecurity risks and highlight biosecurity issues for national leadership. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1659_article.htm
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http://dx.doi.org/10.3201/eid2505.181659DOI Listing
May 2019
2 Reads

Pre-diagnostic blood levels of organochlorines and risk of non-Hodgkin lymphoma in three prospective cohorts in China and Singapore.

Int J Cancer 2019 Apr 19. Epub 2019 Apr 19.

Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Rockville, MD, USA.

Specific organochlorines (OCs) have been associated with non-Hodgkin lymphoma (NHL) with varying degrees of evidence. These associations have not been evaluated in Asia, where the high exposure and historical environmental contamination of certain OC pesticides (e.g. Read More

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http://dx.doi.org/10.1002/ijc.32350DOI Listing

Urine salts elucidate Early Neolithic animal management at Aşıklı Höyük, Turkey.

Sci Adv 2019 Apr 17;5(4):eaaw0038. Epub 2019 Apr 17.

Department of Prehistory, Istanbul University, Istanbul 34134, Turkey.

The process of sheep and goat (caprine) domestication began by 9000 to 8000 BCE in Southwest Asia. The early Neolithic site at Aşıklı Höyük in central Turkey preserves early archaeological evidence of this transformation, such as culling by age and sex and use of enclosures inside the settlement. People's strategies for managing caprines evolved at this site over a period of 1000 years, but changes in the scale of the practices are difficult to measure. Read More

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http://advances.sciencemag.org/lookup/doi/10.1126/sciadv.aaw
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http://dx.doi.org/10.1126/sciadv.aaw0038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469938PMC
April 2019
5 Reads

Two New Species of the Genus from China and Korea.

Mycobiology 2019 Mar 23;47(1):40-49. Epub 2019 Mar 23.

Korean Lichen Research Institute (KoLRI), Sunchon National University, Suncheon, Korea.

is a widespread lineage of lichenized ascomycetes with ambiguous relationships among species that have not solved completely. In this study, several specimens belonging to were collected from China and South Korea, and the internal transcribed spacer region was generated to confirm the system position of the newly collected specimens. Combined with a morphological examination and phylogenetic analysis, two new areolate species, and , are new to science. Read More

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https://www.tandfonline.com/doi/full/10.1080/12298093.2019.1
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http://dx.doi.org/10.1080/12298093.2019.1583785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452912PMC
March 2019
1 Read

Diverse Large HIV-1 Non-subtype B Clusters Are Spreading Among Men Who Have Sex With Men in Spain.

Front Microbiol 2019 3;10:655. Epub 2019 Apr 3.

HIV Biology and Variability Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.

In Western Europe, the HIV-1 epidemic among men who have sex with men (MSM) is dominated by subtype B. However, recently, other genetic forms have been reported to circulate in this population, as evidenced by their grouping in clusters predominantly comprising European individuals. Here we describe four large HIV-1 non-subtype B clusters spreading among MSM in Spain. Read More

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http://dx.doi.org/10.3389/fmicb.2019.00655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457325PMC

Revisiting the Miller-Kanazawa Debate: Should Asia Be Afforded More Attention From Evolutionary Psychologists?

Authors:
Sean T H Lee

Front Psychol 2019 22;10:547. Epub 2019 Mar 22.

School of Social Sciences, Singapore Management University, Singapore, Singapore.

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http://dx.doi.org/10.3389/fpsyg.2019.00547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439342PMC

Acceptability of Mental Health Facilities and De-addiction Centers in India.

J Exp Neurosci 2019 7;13:1179069519839990. Epub 2019 Apr 7.

Department of Pharmacology, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow, India.

Not much is known about disease prevalence, treatment outcomes, trained manpower, programs, and patients' awareness of diseases from South Asia, compared with the Western world. While other aspects are improving, the quantitative evaluation of awareness of diseases is lagging. Compared with other diseases, the situation for mental health disorders and addiction is worse. Read More

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http://dx.doi.org/10.1177/1179069519839990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454643PMC
April 2019
1 Read

New estimates of flood exposure in developing countries using high-resolution population data.

Nat Commun 2019 Apr 18;10(1):1814. Epub 2019 Apr 18.

Fathom, The Engine Shed, Station Approach, Bristol, BS1 6QH, UK.

Current estimates of global flood exposure are made using datasets that distribute population counts homogenously across large lowland floodplain areas. When intersected with simulated water depths, this results in a significant mis-estimation. Here, we use new highly resolved population information to show that, in reality, humans make more rational decisions about flood risk than current demographic data suggest. Read More

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http://dx.doi.org/10.1038/s41467-019-09282-yDOI Listing
April 2019
2 Reads

Evolutionary analysis of influenza A(H1N1)pdm09 during the pandemic and post-pandemic period in Pakistan.

J Infect Public Health 2019 Apr 15. Epub 2019 Apr 15.

Department of Virology, National Institute of Health, Chak Shahzad, Islamabad, Pakistan.

Background: The first case of influenza A(H1N1)pdm09 was detected in Pakistan in June 2009. Since then, it has continued to circulate causing considerable morbidity and mortality. The purpose of this study was to evaluate the evolutionary changes in influenza A(H1N1)pdm09 viruses from 2009 to 2016 and their relevance to the current vaccine viruses. Read More

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http://dx.doi.org/10.1016/j.jiph.2019.03.008DOI Listing

Short- and long-term follow-up of antithrombotic management patterns in patients hospitalized with acute coronary syndrome: Indian subgroup of EPICOR Asia study.

Indian Heart J 2019 Jan - Feb;71(1):25-31. Epub 2019 Jan 3.

Ruby Hospital, Pune, India.

Background: Acute coronary syndrome (ACS) is associated with emergency hospitalizations, and there are limited real-world data on clinical outcomes in post-ACS Asian patients. This article presents data on the Indian subgroup from the Long-term Follow-up of Antithrombotic Management Patterns in Acute Coronary Syndrome Patients in Asia (EPICOR-Asia) study.

Methods: EPICOR included patients with ACS [ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI), or unstable angina (UA)]. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00194832183035
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http://dx.doi.org/10.1016/j.ihj.2018.12.005DOI Listing
January 2019
1 Read

Ticagrelor for Asian patients with acute coronary syndrome in real-world practice: A systematic review and meta-analysis of observational studies.

Indian Heart J 2019 Jan - Feb;71(1):15-24. Epub 2019 Jan 25.

University Hospital of State Medical University of Semey, Department of Endovascular Surgery, Semey, Kazakhstan.

Objective: We aimed to assess the efficacy and safety of ticagrelor compared to clopidogrel in Asian patients with acute coronary syndrome (ACS) in real-world practice.

Methods: PubMed, Web of Science and Scopus databases were searched systematically to obtain relevant Asian observational studies.

Results: The meta-analysis included six studies with 27959 participants. Read More

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http://dx.doi.org/10.1016/j.ihj.2019.01.003DOI Listing
January 2019

First two confirmed cases of Dibothriocephalus nihonkaiensis in Southeast Asia (Singapore).

Pathology 2019 Apr 15. Epub 2019 Apr 15.

Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.pathol.2018.12.420DOI Listing

The incidence, aetiology, and adverse clinical consequences of less severe diarrhoeal episodes among infants and children residing in low-income and middle-income countries: a 12-month case-control study as a follow-on to the Global Enteric Multicenter Study (GEMS).

Lancet Glob Health 2019 May;7(5):e568-e584

University of Maryland School of Medicine, Baltimore, MD, USA.

Background: Diarrheal diseases remain a leading cause of illness and death among children younger than 5 years in low-income and middle-income countries. The Global Enteric Multicenter Study (GEMS) has described the incidence, aetiology, and sequelae of medically attended moderate-to-severe diarrhoea (MSD) among children aged 0-59 months residing in censused populations in sub-Saharan Africa and south Asia, where most child deaths occur. To further characterise this disease burden and guide interventions, we extended this study to include children with episodes of less-severe diarrhoea (LSD) seeking care at health centres serving six GEMS sites. Read More

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http://dx.doi.org/10.1016/S2214-109X(19)30076-2DOI Listing

Health and immunisation services for the urban poor in selected countries of Asia.

Infect Dis Poverty 2019 Apr 18;8(1):26. Epub 2019 Apr 18.

UNICEF Headquarter, New York, USA.

Background: Asia is a region that is rapidly urbanising. While overall urban health is above rural health standards, there are also pockets of deep health and social disadvantage within urban slum and peri-urban areas that represent increased public health risk. With a focus on vaccine preventable disease and immunisation coverage, this commentary describes and analyses strengths and weaknesses of existing urban health and immunisation strategy, with a view to recommending strategic directions for improving access to immunisation and related maternal and child health services in urban areas across the region. Read More

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https://idpjournal.biomedcentral.com/articles/10.1186/s40249
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http://dx.doi.org/10.1186/s40249-019-0538-4DOI Listing
April 2019
1 Read

Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in central and western Asia and the Caucasus.

Parasit Vectors 2019 Apr 18;12(1):175. Epub 2019 Apr 18.

Centre of Excellence for Food and Vector-borne Zoonoses, Institute for Medical Research, University of Belgrade, Dr Subotića 4, Belgrade, 11000, Serbia.

Background: The zoonotic parasite Taenia saginata transmits between humans, the definitive host (causing taeniosis), and bovines as the intermediate host (causing cysticercosis). Central and western Asia and the Caucasus have large cattle populations and beef consumption is widespread. However, an overview of the extent of human T. Read More

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http://dx.doi.org/10.1186/s13071-019-3438-3DOI Listing

Population pharmacokinetics and pharmacodynamics of the artesunate-mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children.

Malar J 2019 Apr 18;18(1):139. Epub 2019 Apr 18.

Drugs for Neglected Diseases initiative, Geneva, Switzerland.

Background: The World Health Organization (WHO) recommends combinations of an artemisinin derivative plus an anti-malarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infections. In Africa, artesunate-mefloquine (ASMQ) is an infrequently used artemisinin-based combination therapy (ACT) because of perceived poor tolerance to mefloquine. However, the WHO has recommended reconsideration of the use of ASMQ in Africa. Read More

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http://dx.doi.org/10.1186/s12936-019-2754-6DOI Listing

Invasive Salmonella infections among children in Bintulu, Sarawak, Malaysian Borneo: a 6-year retrospective review.

BMC Infect Dis 2019 Apr 18;19(1):330. Epub 2019 Apr 18.

Institute of Health and Community Medicine, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.

Background: Invasive Salmonella infections result in significant morbidity and mortality in developing countries. In Asia, typhoid and paratyphoid fever are reported to be the major invasive Salmonella infections, while invasive non-typhoidal Salmonella (iNTS) infections are believed to be uncommon. Data from Sarawak, in Malaysian Borneo, are limited. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3963-xDOI Listing
April 2019
1 Read

Sero-epidemiological status and risk factors of toxoplasmosis in pregnant women in Northern Vietnam.

BMC Infect Dis 2019 Apr 18;19(1):329. Epub 2019 Apr 18.

Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.

Background: In Vietnam, few studies have determined the epidemiological status of toxoplasmosis in pregnant women and no routine prenatal screening is in place. This study was conducted to evaluate the seroprevalence of this zoonotic parasitic infection in pregnant women in Northern Vietnam and to assess the association with awareness, risk factors and congenital toxoplasmosis.

Methods: Approximately 800 pregnant women were included in the study from two hospitals, one in Hanoi and one in Thai Binh province, which is known to have a dense cat population. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3885-7DOI Listing
April 2019
1 Read

APBioNet's annual International Conference on Bioinformatics (InCoB) returns to India in 2018.

BMC Genomics 2019 Apr 18;19(Suppl 9):266. Epub 2019 Apr 18.

Department of Molecular Sciences, Macquarie University, Sydney, NSW, 2109, Australia.

InCoB, one of the largest annual bioinformatics conferences in the Asia-Pacific region since its launch in 2002, returned to New Delhi, India after 12 years, with a conference attendance of 314 delegates. The 2018 conference had sessions on Big Data and Algorithms, Next Generation Sequencing and Omics Science, Structure, Function and Interactions, Disease and Drug Discovery and Plant and Agricultural Bioinformatics. The conference also featured an industry track as well as panel discussions on Women in Bioinformatics and Democratization vs. Read More

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http://dx.doi.org/10.1186/s12864-019-5582-8DOI Listing
April 2019
1 Read

"I'm Trying to Stop Things Before They Happen": Carers' Contributions to Patient Safety in Hospitals.

Qual Health Res 2019 Apr 19:1049732319841021. Epub 2019 Apr 19.

2 Australian Catholic University, Fitzroy, Victoria, Australia.

Patient safety policies increasingly encourage carer (i.e., family or friends) involvement in reducing health care-associated harm in hospital. Read More

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http://dx.doi.org/10.1177/1049732319841021DOI Listing

Benefits and risks of therapeutic alternatives for macrolide resistant Mycoplasma Pneumoniae pneumonia in children.

Authors:
Hyeon-Jong Yang

Korean J Pediatr 2019 Mar 15. Epub 2019 Mar 15.

Pediatric Allergy and Respiratory Center, Department of Pediatrics, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.

Mycoplasma pneumoniae pneumonia (MPP) has been generally susceptible to macrolides, however emergence of macrolide-resistant Mycoplasma pneumoniae pneumonia (MRMP) has made the treatment of MPP challenging. MRMP rapidly spread after 2000s, especially in the Eastern Asia. MRMPs are more common in children and adolescents than in adults, which is likely related to the frequent use of macrolides for treatments of MP infections in children. Read More

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http://dx.doi.org/10.3345/kjp.2018.07367DOI Listing

Discovery and Characterization of Novel Bat Coronavirus Lineages from Kazakhstan.

Viruses 2019 Apr 17;11(4). Epub 2019 Apr 17.

Research Institute for Biological Safety Problems, 080409 Gvardeiskiy, Kordaiskiy rayon, Zhambylskaya oblast, Kazakhstan.

Coronaviruses are positive-stranded RNA viruses that infect a variety of hosts, resulting in a range of symptoms from gastrointestinal illness to respiratory distress. Bats are reservoirs for a high diversity of coronaviruses, and focused surveillance detected several strains genetically similar to MERS-coronavirus, SARS-coronavirus, and the human coronaviruses 229E and NL63. The bat fauna of central Asia, which link China to eastern Europe, are relatively less studied than other regions of the world. Read More

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http://dx.doi.org/10.3390/v11040356DOI Listing

Fabric Composites Reinforced with Thermally Bonded and Irregularly Aligned Filaments: Preparation and Puncture Resistant Performance.

Polymers (Basel) 2019 Apr 17;11(4). Epub 2019 Apr 17.

Department of Medical Research, China Medical University Hospital, China Medical University, Taichung City 40402, Taiwan.

This study proposes fabric composites with improved static and dynamic puncture via increasing a friction force to restrain the slide of filaments as well as the compression and abrasion between the fibers and the puncture probe. The the bi-layered shell layers of composite fabrics are composed of aramid staple fibers and nylon staple fibers and a layer of low-melting-point polyester (LPET). The nonwoven layer consisting of recycled aramid and nylon staple fibers provides a shear effect to dissipate part of the puncture energy. Read More

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http://dx.doi.org/10.3390/polym11040706DOI Listing

Non-Proteasomal UbL-UbA Family of Proteins in Neurodegeneration.

Int J Mol Sci 2019 Apr 17;20(8). Epub 2019 Apr 17.

Department of Applied Biology, Kyoto Institute of Technology, Kyoto 606-8585, Japan.

Ubiquitin-like/ubiquitin-associated proteins (UbL-UbA) are a well-studied family of non-proteasomal ubiquitin receptors that are evolutionarily conserved across species. Members of this non-homogenous family facilitate and support proteasomal activity by promoting different effects on proteostasis but exhibit diverse extra-proteasomal activities. Dysfunctional UbL-UbA proteins render cells, particularly neurons, more susceptible to stressors or aging and may cause earlier neurodegeneration. Read More

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http://dx.doi.org/10.3390/ijms20081893DOI Listing

Transcriptome analyses of Paris polyphylla var. chinensis, Ypsilandra thibetica, and Polygonatum kingianum characterize their steroidal saponin biosynthesis pathway.

Fitoterapia 2019 Apr 15. Epub 2019 Apr 15.

Key Laboratory for Plant Diversity and Biogeography of East Asia, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China; Yunnan Key Laboratory for Integrative Conservation of Plant Species with Extremely Small Population, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China. Electronic address:

Steroidal saponins, one of the most diverse groups of plant-derived natural products, elicit biological and pharmacological activities; however, the genes involved in their biosynthesis and the corresponding biosynthetic pathway in monocotyledon plants remain unclear. This study aimed to identify genes involved in the biosynthesis of steroidal saponins by performing a comparative analysis among transcriptomes of Paris polyphylla var. chinensis (PPC), Ypsilandra thibetica (YT), and Polygonatum kingianum (PK). Read More

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http://dx.doi.org/10.1016/j.fitote.2019.04.008DOI Listing

Leishmaniasis in Istanbul; A new epidemiological data about refugee leishmaniasis.

Acta Trop 2019 Apr 15. Epub 2019 Apr 15.

Department of Medical Microbiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Leishmania is an intracellular parasite, which is transmitted by the bite of infected female Phlebotominae sand flies. Turkey is a crossroad between Europe and Asia that makes it important in terms of epidemiology. In the present study, we aimed to evaluate Leishmania infection among non-autochthonous patients admitted to Health Sciences University, Dr. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0001706X193037
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http://dx.doi.org/10.1016/j.actatropica.2019.04.008DOI Listing
April 2019
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Appearance of Polypoidal Lesions in Patients With Polypoidal Choroidal Vasculopathy Using Swept-Source Optical Coherence Tomographic Angiography.

JAMA Ophthalmol 2019 Apr 18. Epub 2019 Apr 18.

Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Importance: Polypoidal choroidal vasculopathy (PCV) is a major cause of visual loss worldwide, particularly in Asia, and the appropriate understanding of the structures in PCV previously described as polypoidal lesions is important for understanding their pathogenesis, diagnosis, and prognosis.

Objective: To report the morphologic characteristics of polypoidal lesions and their association with branching vascular networks (BVNs) in eyes with PCV using swept-source optical coherence tomographic angiography (SS-OCTA).

Design, Setting, And Participants: This cross-sectional observational study included 20 participants recruited from Shanghai General Hospital with a diagnosis of PCV based on the presence of focal hyperfluorescent spots on indocyanine green angiography (ICGA). Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2019.0449DOI Listing

The possible role of cross-reactive dengue virus antibodies in Zika virus pathogenesis.

PLoS Pathog 2019 Apr 18;15(4):e1007640. Epub 2019 Apr 18.

Department of Viroscience, Erasmus Medical Center, Rotterdam, the Netherlands.

Zika virus (ZIKV) has been known for decades to circulate in Africa and Asia. However, major complications of a ZIKV infection have recently become apparent for reasons that are still not fully elucidated. One of the hypotheses for the seemingly increased pathogenicity of ZIKV is that cross-reactive dengue antibodies can enhance a ZIKV infection through the principle of antibody-dependent enhancement (ADE). Read More

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http://dx.plos.org/10.1371/journal.ppat.1007640
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http://dx.doi.org/10.1371/journal.ppat.1007640DOI Listing
April 2019
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Evaluating the Quality and Readability of Online Resources for Labiaplasty.

Female Pelvic Med Reconstr Surg 2019 Apr 12. Epub 2019 Apr 12.

From the Division of Female Pelvic Medicine and Reconstructive Surgery, Ohio State University Wexner Medical Center, Columbus, OH.

Objectives: The aim of this study was to evaluate the quality, readability, and accuracy of Web-based information regarding labiaplasty and to characterize the types of Web sites providing this information.

Methods: Investigators used 3 major search engines to query the internet using the search terms labiaplasty, labia reduction, and vaginal rejuvenation. Two validated tools were used to evaluate Web sites: the JAMA benchmark tool and the DISCERN instrument. Read More

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http://dx.doi.org/10.1097/SPV.0000000000000725DOI Listing

Elevated Blood Lead Levels Among Resettled Refugee Children in Ohio, 2009-2016.

Am J Public Health 2019 Apr 18:e1-e9. Epub 2019 Apr 18.

The authors are with the College of Public Health, Kent State University, Kent, OH.

To assess the prevalence of and the demographic factors for elevated blood lead level (EBLL; ≥ 5 µg/dL) at resettlement among newly admitted refugee children. This cross-sectional study used data from the postresettlement refugee medical screening of 5661 children resettled in Ohio from 2009 to 2016. We computed prevalence of EBLL and adjusted prevalence ratio with modified Poisson regression modeling. Read More

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http://dx.doi.org/10.2105/AJPH.2019.305022DOI Listing

Strengthening of vector control in South-East Asia: Outcomes from a WHO regional workshop.

J Vector Borne Dis 2018 Oct-Dec;55(4):247-257

Department of Communicable Diseases, World Health Organization, South-East Asia Regional Office, New Delhi, India.

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http://dx.doi.org/10.4103/0972-9062.256559DOI Listing
April 2019
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Artificial Intelligence and Optical Coherence Tomography Imaging.

Asia Pac J Ophthalmol (Phila) 2019 Apr 18. Epub 2019 Apr 18.

Harkness Eye Institute, Columbia University, New York, United States.

This review article aimed to highlight the application and use of artificial intelligence (AI) in optical coherence tomography (OCT) imaging in ophthalmology. Artificial intelligence programs seek to simulate intelligent human behavior in computers. With an abundance of patient data, especially with the advent and growing use of imaging modalities such as OCT, AI programs provide us with the unique opportunity to analyze this plethora of information and assist in making clinical decisions in the field of ophthalmology. Read More

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http://www.apjo.org/Apjo/pdf/id/654.html
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http://dx.doi.org/10.22608/APO.201904DOI Listing
April 2019
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