807,763 results match your criteria Asia Pacific Journal Of Tourism Research[Journal]


Comparative evaluation of cerebral gliomas using rCBV measurements during sequential acquisition of T1-perfusion and T2*-perfusion MRI.

PLoS One 2019 24;14(4):e0215400. Epub 2019 Apr 24.

Philips Health Tech Asia Pacific, Minato-ku Tokyo, Japan.

Objective: To assess the inter-technique agreement of relative cerebral blood volume (rCBV) measurements obtained using T1- and T2*-perfusion MRI on 3T scanner in glioma patients.

Methods: A total of 49 adult patients with gliomas underwent both on T1- and T2*-perfusion in the same scanning session, and rCBV maps were estimated using both methods. For the quantitative analysis; Two independent observers recorded the rCBV values from the tumor as well as contralateral brain tissue from both T1- and T2*-perfusion. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215400PLOS

A Multi-Institutional International Analysis of Textbook Outcomes Among Patients Undergoing Curative-Intent Resection of Intrahepatic Cholangiocarcinoma.

JAMA Surg 2019 Apr 24:e190571. Epub 2019 Apr 24.

The Ohio State University Wexner Medical Center, Columbus.

Importance: Composite measures may be superior to individual measures for the analysis of hospital performance and quality of surgical care.

Objective: To determine the incidence of a so-called textbook outcome, a composite measure of the quality of surgical care, among patients undergoing curative-intent resection of intrahepatic cholangiocarcinoma.

Design, Setting, And Participants: This cohort study involved an analysis of a multinational, multi-institutional cohort of patient from 15 major hepatobiliary centers in North America, Europe, Australia, and Asia who underwent curative-intent resection of intrahepatic cholangiocarcinoma between 1993 and 2015. Read More

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http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamasurg.2019.0571DOI Listing
April 2019
1 Read

[Advances in etiology, epidemiology and genetic diversity of ].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019 Mar;31(1):86-93

Department of Parasitology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450052, China.

and are three causative agents of human thelaziasis. Most of the reported cases were caused by , occurring in the old world, particularly in Asian and European countries. and have rarely been reported infecting humans in North America. Read More

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http://www.cnki.net/kcms/doi/10.16250/j.32.1374.2018300.html
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http://dx.doi.org/10.16250/j.32.1374.2018300DOI Listing
March 2019
1 Read

[Epidemic and research progress of babesiosis].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019 Mar;31(1):63-70

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, China.

Babesiosis is an emerging parasitic disease, distributed globally in Europe, Asia, Africa, North and South America, and Australia, and the United States is still the country with the largest number of babesiosis cases reported. Babesiosis in China is mainly distributed in the northeast, followed by the southwest and other regions. As a new vector-borne infectious disease, babesiosis poses a serious threat to human health, and its research foundation is relatively weak, so it requires more attention and recognition. Read More

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http://dx.doi.org/10.16250/j.32.1374.2018293DOI Listing
March 2019
1 Read

Artificial Intelligence in Diabetic Eye Disease Screening.

Asia Pac J Ophthalmol (Phila) 2019 Apr 24. Epub 2019 Apr 24.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.

Systematic or national screening programs for diabetic retinopathy (DR) and diabetic macular edema (DME), using digital fundus photography and optical coherence tomography (OCT), are currently implemented at primary care level, aiming to provide timely referral for vision-threatening DR and DME to ophthalmologists for timely treatment and vision loss prevention. However, interpretation of retinal images requires specialized knowledge and expertise in diabetic eye disease. Furthermore, current DR screening programs are capital- and labor-intensive, which makes it difficult to rapidly scale up and expand diabetic eye screening to meet the needs of this growing global epidemic. Read More

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http://www.apjo.org/Apjo/pdf/id/655.html
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http://dx.doi.org/10.22608/APO.201976DOI Listing
April 2019
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Optical Coherence Tomography for the Diagnosis and Monitoring of Glaucoma.

Authors:
Ahnul Ha Ki Ho Park

Asia Pac J Ophthalmol (Phila) 2019 Apr 24. Epub 2019 Apr 24.

Department of Medicine, Seoul National University College of Medicine, Seoul, South Korea.

Since its introduction to the field of ophthalmology, optical coherence tomography (OCT) has been markedly improved in terms of imaging protocols, algorithms, and new parameters that have enhanced its utility for the diagnosis and assessment of glaucoma progression. In this review, we examine the clinical utility of OCT in the diagnosis of glaucoma and monitoring of its progression, and emphasize the technological advances that facilitate both glaucoma research and the formulation of clinical management strategies. Read More

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http://dx.doi.org/10.22608/APO.201902DOI Listing

Editorial Comment to The Urological Association of Asia clinical guideline for urinary stone disease.

Int J Urol 2019 Apr 24. Epub 2019 Apr 24.

Department of Urology, Chiba University Graduate School of Medicine, Chiba, Japan.

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http://dx.doi.org/10.1111/iju.13958DOI Listing

The Urological Association of Asia clinical guideline for urinary stone disease.

Int J Urol 2019 Apr 24. Epub 2019 Apr 24.

Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

The Urological Association of Asia, consisting of 25 member associations and one affiliated member since its foundation in 1990, has planned to develop Asian guidelines for all urological fields. The field of stone diseases is the third of its guideline projects. Because of the different climates, and social, economic and ethnic environments, the clinical practice for urinary stone diseases widely varies among the Asian countries. Read More

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http://dx.doi.org/10.1111/iju.13957DOI Listing

Malignant Helicobacter pylori-Associated Diseases: Gastric Cancer and MALT Lymphoma.

Adv Exp Med Biol 2019 Apr 24. Epub 2019 Apr 24.

Division of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Helicobacter pylori is the first bacterium formally recognized to play a causative role in human malignancies, gastric cancer and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Evidence accumulates that H. pylori cagA-positive strains play a crucial role in the neoplastic transformation of mammalian cells. Read More

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http://dx.doi.org/10.1007/5584_2019_363DOI Listing

Variability analysis in PM2.5 monitoring.

Data Brief 2019 Jun 14;24:103774. Epub 2019 Mar 14.

Guru Gobind Singh Indraprastha University, India.

United States Environmental Protection Agency (US EPA) and Central Pollution Control Board (CPCB) are two major air quality monitoring agencies in India that measure the concentration of particulate matter of size up to 2.5 μm (PM2.5). Read More

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http://dx.doi.org/10.1016/j.dib.2019.103774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468191PMC

Pulmonary Rehabilitation for Exercise Tolerance and Quality of Life in IPF Patients: A Systematic Review and Meta-Analysis.

Biomed Res Int 2019 21;2019:8498603. Epub 2019 Mar 21.

Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.

Objective: The aim of this study is to evaluate the efficacy and safety of pulmonary rehabilitation (PR) in patients with idiopathic pulmonary fibrosis (IPF). s. Embase, PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), Chongqing VIP (CQVIP), Wanfang Data, and Chinese Biomedical Literature Database (SinoMed) were comprehensively searched. Read More

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http://dx.doi.org/10.1155/2019/8498603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448340PMC
March 2019
3 Reads

Adverse Effect Profile and Effectiveness of Sodium Glucose Co-transporter 2 Inhibitors (SGLT2i) - A Prospective Real-world Setting Study.

Indian J Endocrinol Metab 2019 Jan-Feb;23(1):50-55

Division of Endocrinology and Diabetes, Medanta The Medicity, Gurugram, Haryana, India.

Background: Clinical trials have shown promising results in terms of glycemic control and weight reduction with the use of sodium glucose co-transporter 2 inhibitors (SGLT2i) in type 2 diabetes mellitus (T2DM). However, real-world evidence from standard clinical practice especially from Asia is still limited. The aim of this study was to evaluate the safety and effectiveness of SGLT2i in patients with T2DM in real-world setting. Read More

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http://dx.doi.org/10.4103/ijem.IJEM_566_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446693PMC

Upward elevation and northwest range shifts for alpine species in the Himalaya-Hengduan Mountains region.

Ecol Evol 2019 Apr 11;9(7):4055-4064. Epub 2019 Mar 11.

Germplasm Bank of Wild Species Kunming Institute of Botany, Chinese Academy of Sciences Kunming Yunnan China.

Climate change may impact the distribution of species by shifting their ranges to higher elevations or higher latitudes. The impacts on alpine plant species may be particularly profound due to a potential lack of availability of future suitable habitat. To identify how alpine species have responded to climate change during the past century as well as to predict how they may react to possible global climate change scenarios in the future, we investigate the climatic responses of seven species of , a representative genus endemic in the alpine meadow and subnival region of the Himalaya-Hengduan Mountains. Read More

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http://dx.doi.org/10.1002/ece3.5034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467849PMC

Novel DNA Biosensor for Direct Determination of Carrageenan.

Sci Rep 2019 Apr 23;9(1):6379. Epub 2019 Apr 23.

Southeast Asia Disaster Prevention Research Initiative (SEADPRI-UKM), Institute for Environment and Development (LESTARI), Universiti Kebangsaan Malaysia, 43600 UKM, Bangi, Selangor Darul Ehsan, Malaysia.

A novel disposable electrochemical biosensor based on immobilized calf thymus double-stranded DNA (dsDNA) on the carbon-based screen-printed electrode (SPE) is developed for rapid biorecognition of carrageenan by using methylene blue (MB) redox indicator. The biosensor protocol for the detection of carrageenan is based on the concept of competitive binding of positively charged MB to the negatively charged dsDNA and carrageenan. The decrement in the MB cathodic peak current (i) signal as a result of the released MB from the immobilized dsDNA, and attracted to the carrageenan can be monitored via differential pulse voltammetry (DPV). Read More

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http://dx.doi.org/10.1038/s41598-019-42757-yDOI Listing

Efficacy and resistance of different artemisinin-based combination therapies: a systematic review and network meta-analysis.

Parasitol Int 2019 Apr 20. Epub 2019 Apr 20.

Department of Immunogenetics, Institute of Tropical Medicine (NEKKEN), Leading Graduate School Program, Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto, Nagasaki, Japan. Electronic address:

Background: Malaria parasites have developed resistance to most of the known antimalarial drugs in clinical practice, with reports of artemisinin resistance emerging in South East Asia (SEA). We sort to find the status of artemisinin resistance and efficacy of different modalities of the current artemisinin-based combination therapies (ACTs).

Methods: We carried out a systematic search in 11 electronic databases to identify in vivo studies published between 2001 and 2017 that reported artemisinin resistance. Read More

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http://dx.doi.org/10.1016/j.parint.2019.04.016DOI Listing
April 2019
2 Reads

Redescription and supplementary molecular characteristics of Aspidogaster ijimai Kawamura, 1915 (Trematoda, Aspidogastrea, Aspidogastridae), a parasite of Cyprinus carpio Linnaeus, 1758 s. lato (Actinopterygii) and freshwater bivalves in East Asia.

Parasitol Int 2019 Apr 20. Epub 2019 Apr 20.

Department of Ecosystem Studies, School of Environmental Science, University of Shiga Prefecture, Hikone, Japan.

A detailed morphological description and ribosomal DNA (rDNA) sequence molecular data for Aspidogaster ijimai from Japan are provided. Morphological analysis, including a description of the cirrus-sac, indicate the conspecificity of Japanese and continental East Asian A. ijimai specimens. Read More

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http://dx.doi.org/10.1016/j.parint.2019.04.017DOI Listing

Self-reported prevalence and severity of opioid and kratom (Mitragyna speciosa korth.) side effects.

J Ethnopharmacol 2019 Apr 20:111876. Epub 2019 Apr 20.

Centre for Drug Research, Universiti Sains Malaysia, 11800, Minden, Penang, Malaysia.

Ethnopharmacological Relevance: Mitragyna speciosa (Korth.) is a traditional medicinal plant widely used in Southeast Asia for its opioid-like effects. Although kratom produces analgesia through binding of mitragynine and other alkaloids at the mu-opioid receptor (MOR), the association of long-term kratom use with adverse opioid-like effects remains unknown. Read More

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http://dx.doi.org/10.1016/j.jep.2019.111876DOI Listing

Analysis of serum Haptoglobin using glycoproteomics and lectin immunoassay in liver diseases in Hepatitis B virus infection.

Clin Chim Acta 2019 Apr 20. Epub 2019 Apr 20.

Transfusion Transmitted Diseases Department, National Institute of Immunohaematology (ICMR), 13th Floor, New Multi-storeyed Bldg, KEM Hospital Campus, Parel, Mumbai 400 012, Maharashtra, India. Electronic address:

Background: Hepatocellular carcinoma (HCC) due to Hepatitis B viral (HBV) infection is major cause in Asia-Pacific countries. Its early detection is of paramount importance using a marker having both sensitivity and specificity. The present study promises diagnostic and prognostic markers by the identification of site specific glycoforms on Haptoglobin (Hp) using LC-MS/MS and lectin ELISA in liver diseased conditions in HBV infection. Read More

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http://dx.doi.org/10.1016/j.cca.2019.04.072DOI Listing

The first detection of Ashworthius sidemi (Nematoda, Trichostrongylidae) in roe deer (Capreolus capreolus) in Russia.

Vet Parasitol Reg Stud Reports 2018 Dec 20;14:200-203. Epub 2018 Nov 20.

Voronezh State Natural Biosphere Reserve, Voronezh 394080, Russia; Voronezh State Agricultural University, Ul. Mitchurina, 1, Voronezh 394087, Russia.

Ashworthius sidemi is a blood-sucking nematode, which has spread out among wild ruminants in several European countries during last decades. The nematode has recently been detected in cattle as well. The distribution of A. Read More

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http://dx.doi.org/10.1016/j.vprsr.2018.11.003DOI Listing
December 2018

Endogenous Endophthalmitis Caused by Infective Endocarditis in East Asia.

Ophthalmol Retina 2019 Apr 12;3(4):382-384. Epub 2019 Jan 12.

Department of Ophthalmology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan.

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http://dx.doi.org/10.1016/j.oret.2019.01.007DOI Listing

Plasmodium knowlesi and other malaria parasites in long-tailed macaques from the Philippines.

Malar J 2019 Apr 24;18(1):147. Epub 2019 Apr 24.

Animal Biology Division, Institute of Biological Sciences, University of the Philippines Los, Baños, 4031, Los Baños, Laguna, Philippines.

Background: Macaca fascicularis (long-tailed macaque) is the most widespread species of macaque in Southeast Asia and the only species of monkey found naturally in the Philippines. The species is the natural host for the zoonotic malaria species, Plasmodium knowlesi and Plasmodium cynomolgi and for the potentially zoonotic species, Plasmodium inui. Moreover, other Plasmodium species such as Plasmodium coatneyi and Plasmodium fieldi are also natural parasites of M. Read More

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http://dx.doi.org/10.1186/s12936-019-2780-4DOI Listing

Clade-age-dependent diversification under high species turnover shapes species richness disparities among tropical rainforest lineages of Bulbophyllum (Orchidaceae).

BMC Evol Biol 2019 Apr 24;19(1):93. Epub 2019 Apr 24.

Department of Biosciences, University of Salzburg, Hellbrunnerstrasse 34, 5020, Salzburg, Austria.

Background: Tropical rainforests (TRFs) harbour almost half of the world's vascular plant species diversity while covering only about 6-7% of land. However, why species richness varies amongst the Earth's major TRF regions remains poorly understood. Here we investigate the evolutionary processes shaping continental species richness disparities of the pantropical, epiphytic and mostly TRF-dwelling orchid mega-genus Bulbophyllum (c. Read More

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http://dx.doi.org/10.1186/s12862-019-1416-1DOI Listing

Nucleus, Cytoskeleton, and Mitogen-Activated Protein Kinase p38 Dynamics during In Vitro Maturation of Porcine Oocytes.

Animals (Basel) 2019 Apr 13;9(4). Epub 2019 Apr 13.

Department of Animal Science, National Chung Hsing University, Taichung 40227, Taiwan.

The mitogen-activated kinase (MAPK) p38, a member of the MAPK subfamily, is conserved in all mammalian cells and plays important roles in response to various physiologic cues, including mitogens and heat shock. In the present study, MAPK p38 protein expression in porcine oocytes was analyzed during in vitro maturation (IVM) by Western blotting and immunocytochemistry. The levels of p-p38 or activated p38 and p38 expression were at the lowest in the germinal vesicle (GV) stage oocyte, gradually rising at the germinal vesicle breakdown (GVBD) and then reaching a plateau throughout the IVM culture ( < 0. Read More

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http://dx.doi.org/10.3390/ani9040163DOI Listing

Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo.

Antioxidants (Basel) 2019 Apr 12;8(4). Epub 2019 Apr 12.

School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan.

Resveratrol (RSV) is a polyphenolic phytoalexin found in peanuts, grapes, and other plants. Uterine fibroids (UF) are benign growths that are enriched in extracellular matrix (ECM) proteins. In this study, we aimed to investigate the effects of RSV on UF using in vivo and in vitro approaches. Read More

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http://dx.doi.org/10.3390/antiox8040099DOI Listing

Association between Dipeptidyl Peptidase-4 Inhibitors and Allergic Rhinitis in Asian Patients with Diabetes.

Int J Environ Res Public Health 2019 Apr 12;16(8). Epub 2019 Apr 12.

Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 404, Taiwan.

In this retrospective study, we attempted to evaluate the association between dipeptidyl peptidase-4 (DPP-4) inhibitors and allergic rhinitis in patients with diabetes. We analyzed the Longitudinal Health Insurance Database 2000 subdatabase. Our study population included patients with type 2 diabetes (ICD-9-CM 250) between 2009 and 2012, and the study groups were DPP-4 inhibitor users and nonusers. Read More

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http://dx.doi.org/10.3390/ijerph16081323DOI Listing

Psychosocial Management Before, During, and After Emergencies and Disasters-Results from the Kobe Expert Meeting.

Int J Environ Res Public Health 2019 Apr 12;16(8). Epub 2019 Apr 12.

National Institute of Mental Health, National Center for Neurology and Psychiatry, Kodaira 187-0031, Japan.

Emergencies and disasters typically affect entire communities, cause substantial losses and disruption, and result in a significant and persistent mental health burden. There is currently a paucity of evidence on safe and effective individual- and community-level strategies for improving mental health before, during, and after such events. In October 2018, the World Health Organization (WHO) Centre for Health Development (WHO Kobe Centre) convened a meeting bringing together leading Asia Pacific and international disaster research experts. Read More

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http://dx.doi.org/10.3390/ijerph16081309DOI Listing

Ameliorative Effects of on Cognitive Impairment Via Enhancing Cholinergic Functions and Brain-Derived Neurotrophic Factor Expression in -Amyloid-Induced Mice.

J Med Food 2019 Apr 23. Epub 2019 Apr 23.

1 Department of Biochemistry and Molecular Biology, Center for Chronic Metabolic Disease Research, Brain Korea 21 Project for Medical Sciences, Severance Medical Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Alzheimer's disease accounts for the majority of dementia and shows hallmarks such as sequential cognitive dysfunction and abnormal behavior. (DM) has traditionally been used to treat a variety of diseases in East Asia. The aim of this study was to assess the therapeutic effects of DM on brain neuron damage and on cognitive deficit in neuronal cell induced by A in mice. Read More

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http://dx.doi.org/10.1089/jmf.2018.4375DOI Listing

Acupuncture for Primary Insomnia: An Updated Systematic Review of Randomized Controlled Trials.

J Altern Complement Med 2019 Apr 23. Epub 2019 Apr 23.

1 Beijing University of Chinese Medicine, Beijing, China.

Acupuncture as one of the alternative therapies for insomnia is widely used in Asia and increasingly employed in western countries. To provide updated evidence from randomized controlled trials (RCTs) on the effectiveness and safety of acupuncture for primary insomnia. A comprehensive literature search in 11 databases was conducted from January 2008 to October 2017. Read More

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http://dx.doi.org/10.1089/acm.2018.0046DOI Listing

[Results and limitations of epidemiological studies on food allergy. Focus on tropical countries].

Rev Alerg Mex 2019 Jan-Mar;66(1):9-17

Universidad de Antioquía, Grupo de Alergología Clínica y Experimental, Antioquía, Colombia.

Allergy and food atopy are a consequence of immune responses unadapted to antigens mediated by common and otherwise harmless foods. Food allergy (AF) occurs frequently in children under three years of 3 to 15%, as well as in people over 6 to 8%. AF may be mediated by immunoglobulin E or cellular mechanisms and may present with a wide variety of symptoms in the skin, respiratory and gastrointestinal tracts. Read More

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http://dx.doi.org/10.29262/ram.v66i1.340DOI Listing

Socioeconomic position and use of healthcare in the last year of life: A systematic review and meta-analysis.

PLoS Med 2019 Apr 23;16(4):e1002782. Epub 2019 Apr 23.

Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King's College London, London, United Kingdom.

Background: Low socioeconomic position (SEP) is recognized as a risk factor for worse health outcomes. How socioeconomic factors influence end-of-life care, and the magnitude of their effect, is not understood. This review aimed to synthesise and quantify the associations between measures of SEP and use of healthcare in the last year of life. Read More

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http://dx.doi.org/10.1371/journal.pmed.1002782DOI Listing

Driving factors of agricultural virtual water trade between China and the Belt and Road countries.

Environ Sci Technol 2019 Apr 23. Epub 2019 Apr 23.

China proposed the Belt and Road Initiative (BRI), an unprecedented development strategy in terms of scope and scale, to increase the connectivity with the rest of the world by infrastructure development and trade activities. Recently, more attention has been directed to the environmental implications of the international trade activities under this initiative, which contributes to the development of a green, i.e. Read More

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http://dx.doi.org/10.1021/acs.est.9b00093DOI Listing

Narrow pollen diets are associated with declining Midwestern bumble bee species.

Ecology 2019 Apr 23:e02697. Epub 2019 Apr 23.

Department of Entomology, Michigan State University, East Lansing, Michigan, 48824, USA.

Many species of bumble bee (Bombus) have declined in range and abundance across Europe, the Americas, and Asia, whereas other species have persisted and remain common and widespread. One explanation as to why some species have declined, based primarily on studies of the European bumble bee fauna, is that declining species have relatively narrow pollen-foraging niches and are less able to use alternative host plants in the absence of their preferred hosts. Though extensively explored in Europe, this hypothesis has not been investigated in North America, in part due to incomplete information on the foraging niche of many species. Read More

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http://dx.doi.org/10.1002/ecy.2697DOI Listing

Outcomes of universal germline testing for men with prostate cancer in an Australian tertiary center.

Asia Pac J Clin Oncol 2019 Apr 22. Epub 2019 Apr 22.

Kinghorn Cancer Centre, St. Vincent's Hospital, Darlinghurst, NSW, Australia.

Aim: The role of germline testing in prostate cancer is evolving and knowledge of an individual's genetic profile may be used to guide not only an assessment of their familial risk but also have prognostic and therapeutic implications. Although international guidelines have incorporated recommendations for germline testing in prostate cancer, there is little Australian data to guide referrals. The aim of this study is to review the frequency of relevant pathogenic mutations in an Australian center, their associated clinical factors and clinical impact. Read More

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http://dx.doi.org/10.1111/ajco.13148DOI Listing

Association between glaucoma and the risk of Alzheimer's disease: A systematic review of observational studies.

Acta Ophthalmol 2019 Apr 23. Epub 2019 Apr 23.

Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang, China.

To address inconsistency as well as investigate the relationship between glaucoma and the risk of Alzheimer's disease (AD). We systematically conducted this meta-analysis based on observational studies published up to 15 January 2018, identified from PubMed and Web of Science. Two team members independently extracted the data and assessed the quality of each included study. Read More

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http://dx.doi.org/10.1111/aos.14114DOI Listing

Differential abundance and core members of the bacterial community associated with wild male Zeugodacus cucurbitae fruit flies (Insecta: Tephritidae) from three geographical regions of Southeast Asia.

Mol Biol Rep 2019 Apr 22. Epub 2019 Apr 22.

Institute of Ocean and Earth Sciences, University of Malaya, 50603, Kuala Lumpur, Malaysia.

Zeugodacus cucurbitae (Coquillet) is one of the most significant and widespread tephritid pest species of agricultural crops. This study reports the bacterial communities associated with Z. cucurbitae from three geographical regions in Southeast Asia (Thailand, Peninsular Malaysia, and Sarawak). Read More

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http://dx.doi.org/10.1007/s11033-019-04818-3DOI Listing

Trends and Health Risks of Dissolved Heavy Metal Pollution in Global River and Lake Water from 1970 to 2017.

Rev Environ Contam Toxicol 2019 Apr 24. Epub 2019 Apr 24.

College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, China.

Heavy metal pollution in surface water is a global environmental problem. This study analyzed the trends, health risks, and sources of eight dissolved heavy metal species in river and lake water across five continents (Africa, Asia, Europe, North America, and South America; Oceania was excluded owing to a lack of data) for the period 1970-2017. We wanted to assess the effects of various implemented countermeasures to pollution and to determine those that could be adopted worldwide. Read More

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http://link.springer.com/10.1007/398_2019_27
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http://dx.doi.org/10.1007/398_2019_27DOI Listing
April 2019
1 Read

Precision surgical approach with lymph-node dissection in early gastric cancer.

World J Gastroenterol 2019 Apr;25(14):1640-1652

Department of Surgical Oncology, Kanazawa Medical University, Ishikawa 920-0293, Japan.

The gravest prognostic factor in early gastric cancer is lymph-node metastasis, with an incidence of about 10% overall. About two-thirds of early gastric cancer patients can be diagnosed as node-negative prior to treatment based on clinic-pathological data. Thus, the tumor can be resected by endoscopic submucosal dissection. Read More

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http://dx.doi.org/10.3748/wjg.v25.i14.1640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465935PMC

Advance Care Planning for Older People with Cancer and Its Implications in Asia: Highlighting the Mental Capacity and Relational Autonomy.

Geriatrics (Basel) 2018 Jul 20;3(3). Epub 2018 Jul 20.

Department of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

With dramatically increasing proportions of older people, global ageing has remarkably influenced healthcare services and policy making worldwide. Older people represent the majority of patients with cancer, leading to the increasing demand of healthcare due to more comorbidities and inherent frailty. The preference of older people with cancer are often ignored, and they are considered incapable of making choices for themselves, particularly medical decisions. Read More

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http://dx.doi.org/10.3390/geriatrics3030043DOI Listing

Effects of dietary supplementation with different level and molecular weight of fungal β-glucan on performances, health and meat quality in broilers.

Asian-Australas J Anim Sci 2019 Mar 7. Epub 2019 Mar 7.

Asia Star Trade Co., Ltd., Bangkok, 10400, Thailand.

Objective: To investigate the effects of dietary supplementation with different levels and molecular weights of fungal β-glucan on productive performances, health, carcass traits and meat quality in broilers.

Methods: Two hundred and ten of one-day-old chicks with equal sex were assigned to seven experimental groups in 2×4 factorial arrangement. These groups were supplemented with (0, 10, 30 and 60 ppm) of molecular weight 1-3, 1-6 β-glucan (low or high). Read More

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http://dx.doi.org/10.5713/ajas.18.0927DOI Listing

Prevalence of antenatal depression in South Asia: a systematic review and meta-analysis.

J Epidemiol Community Health 2019 Apr 22. Epub 2019 Apr 22.

Department of Statistics and Computer Science, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka.

Objective: To estimate the prevalence of antenatal depression in South Asia and to examine variations by country and study characteristics to inform policy, practice and future research.

Methods: We conducted a comprehensive search of 13 databases including international databases and databases covering scientific literature from South Asian countries in addition to Google Scholar and grey sources from 1 January 2007 to 31 May 2018. Studies reporting prevalence estimates of antenatal depression using a validated diagnostic/screening tool were identified, screened, selected and appraised. Read More

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http://dx.doi.org/10.1136/jech-2018-211819DOI Listing

Consensus Statement on the Use of Bone Turnover Markers for Short-Term Monitoring of Osteoporosis Treatment in the Asia-Pacific Region.

J Clin Densitom 2019 Mar 20. Epub 2019 Mar 20.

Department of Orthopaedics, College of Medicine, National Taiwan University & Hospital, Taipei, Taiwan. Electronic address:

Osteoporosis is a major health issue. By 2050, a greater than 2-fold increase in patients number with hip fractures will occur in Asia representing 50% of all hip fractures worldwide. For the Asia-Pacific (AP) region, more efforts on controlling osteoporosis and the subsequent fractures are crucial. Read More

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http://dx.doi.org/10.1016/j.jocd.2019.03.004DOI Listing

Late Middle Pleistocene hominin teeth from Tongzi, southern China.

J Hum Evol 2019 May 28;130:96-108. Epub 2019 Mar 28.

Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), Paseo de la Sierra de Atapuerca s/n, 09002, Burgos, Spain; UCL Anthropology, 14 Taviton Street, WC1H 0BW, London, UK.

In 1972 and 1983, four hominin teeth were recovered from Yanhui Cave, Tongzi, southern China and assigned to later Homo erectus or archaic Homo sapiens. The teeth can be dated to approximately 172,000-240,000 years before present. Here, in addition to the standard morphological comparisons, we reevaluate the morphology of the hominin teeth using geometric morphometric analyses and micro-computed tomography (micro-CT) scans. Read More

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http://dx.doi.org/10.1016/j.jhevol.2019.03.001DOI Listing

Temporal shifts in the distribution of murine rodent body size classes at Liang Bua (Flores, Indonesia) reveal new insights into the paleoecology of Homo floresiensis and associated fauna.

J Hum Evol 2019 May 14;130:45-60. Epub 2019 Mar 14.

Australian Research Council Centre of Excellence for Australian Biodiversity and Heritage, University of Adelaide, Adelaide, South Australia 5005, Australia; School of Biological Sciences, Environment Institute, and Centre for Applied Conservation Science, University of Adelaide, Adelaide, South Australia 5005 Australia.

Liang Bua, the type locality of Homo floresiensis, is a limestone cave located in the western part of the Indonesian island of Flores. The relatively continuous stratigraphic sequence of the site spans the past ∼190 kyr and contains ∼275,000 taxonomically identifiable vertebrate skeletal elements, ∼80% of which belong to murine rodent taxa (i.e. Read More

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http://dx.doi.org/10.1016/j.jhevol.2019.02.002DOI Listing

Lupeol suppresses migration and invasion via p38/MAPK and PI3K/Akt signaling pathways in human osteosarcoma U-2 OS cells.

Biosci Biotechnol Biochem 2019 Apr 22:1-11. Epub 2019 Apr 22.

a Department of Biological Science and Technology , China Medical University , Taichung , Taiwan.

Lupeol, one of the common components from the fruits and natural foods, has been reported to exert antitumor activities in many human cancer cell lines; however, its effects on osteosarcoma cell metastasis were not elucidated. In the present study, lupeol at 10-25 μM induced cell morphological changes and decreased total viable cell number in U-2 OS cells. Lupeol (5-15 μM) suppressed cell mobility, migration, and invasion by wound healing and transwell chamber assays, respectively. Read More

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http://dx.doi.org/10.1080/09168451.2019.1606693DOI Listing

A Loop-Mediated Isothermal Amplification Assay for Rapid Detection of that Causes Soft Rot in Konjac.

Int J Mol Sci 2019 Apr 19;20(8). Epub 2019 Apr 19.

The Key Lab of Plant Pathology of Hubei Province, Huazhong Agricultural University, Wuhan 430070, China.

Bacterial soft rot caused by species is a serious disease in konjac (), a healthy source of starch particularly in East Asia. An effective diagnostic method is crucial to control the disease and reduce losses in konjac production. In this study, we evaluated a loop-mediated isothermal amplification (LAMP) assay with a specific primer set for the rapid and accurate detection of . Read More

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http://dx.doi.org/10.3390/ijms20081937DOI Listing

A Novel Aquaporin 12-like Protein from : Characterization and Functional Analysis.

Genes (Basel) 2019 Apr 21;10(4). Epub 2019 Apr 21.

College of Horticulture and Plant Protection & Institute of Applied Entomology, Yangzhou University, Yangzhou 225009, China.

Aquaporins (AQPs), which are members of the major intrinsic protein (MIP) family, play an important role in the transport of water and other small, uncharged solutes across membranes. In this study, we identified gene encoding two aquaporin 12-like (AQP12L) proteins, and , from , a serious rice pest in Asia. Phylogenetic analysis indicated that AQP12L_V1 and AQP12L_V2 were grouped in a well-supported cluster that included other members of Lepidoptera. Read More

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http://dx.doi.org/10.3390/genes10040311DOI Listing

Ethnic variation in acute cerebrovascular disease: Analysis from the Qatar stroke registry.

Eur Stroke J 2016 Sep 10;1(3):231-241. Epub 2016 Aug 10.

The Neuroscience Institute (Stroke Center of Excellence), Hamad Medical Corporation & Department of Medicine, University of Alberta, Alberta, Canada.

Objective: We analysed the Qatar stroke registry for ethnic variations in patients admitted with cerebrovascular disease at Hamad General Hospital, Qatar.

Methods: Patients admitted with acute stroke from January 2014 to December 2015, enrolled in the registry were included in the study. We evaluated the clinical presentation, risk factors, and outcome at discharge and 90 days post-discharge in relation to the patient's ethnic background. Read More

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http://dx.doi.org/10.1177/2396987316663776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301242PMC
September 2016

Soil properties, seasonality and crop growth stage exert a stronger effect on rhizosphere prokaryotes than the fungal biocontrol agent f.sp. .

Appl Soil Ecol 2016 Sep;105:126-136

Institute of Agricultural Sciences in the Tropics (Hans-Ruthenberg-Institute), University of Hohenheim, Stuttgart, Germany.

f.sp. (Fos) is an effective biocontrol agent (BCA) against the parasitic weed . Read More

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http://dx.doi.org/10.1016/j.apsoil.2016.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472298PMC
September 2016

Gender, Assets, and Agricultural Development: Lessons from Eight Projects.

World Dev 2016 Jul;83:295-311

International Food Policy Research Institute (IFPRI), USA.

Ownership of assets is important for poverty reduction, and women's control of assets is associated with positive development outcomes at the household and individual levels. This research was undertaken to provide guidance for agricultural development programs on how to incorporate gender and assets in the design, implementation, and evaluation of interventions. This paper synthesizes the findings of eight mixed-method evaluations of the impacts of agricultural development projects on individual and household assets in seven countries in Africa and South Asia. Read More

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http://dx.doi.org/10.1016/j.worlddev.2016.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472297PMC

The effect of Xiang-Sha-Liu-Jun-Zi tang (XSLJZT) on irritable bowel syndrome: A randomized, double-blind, placebo-controlled trial.

J Ethnopharmacol 2019 Apr 19:111889. Epub 2019 Apr 19.

Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan; Chinese Medicine Research Center, China Medical University, Taichung 40402, Taiwan; Research Center for Chinese Medicine and Acupuncture, China Medical University, Taichung 40402, Taiwan; Department of Chinese Medicine, China Medical University Hospital, Taichung 40447, Taiwan. Electronic address:

Background: Irritable bowel syndrome (IBS) is characterized by chronic, recurrent abdominal pain or abdominal discomfort and changes in defecation habits. Xiang-Sha-Liu-Jun-Zi tang (XSLJZT) is a traditional Chinese medical formula that can modulate gastrointestinal disturbance.

Purpose: To investigate the therapeutic effect of XSLJZT on IBS. Read More

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http://dx.doi.org/10.1016/j.jep.2019.111889DOI Listing
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