883,902 results match your criteria Asia Pacific Journal Of Anthropology[Journal]


Defining EUS Features of Chronic Pancreatitis in Asians - A Multicentre Validation Study.

Endoscopy 2020 Jul 10. Epub 2020 Jul 10.

National University Hospital, Division of Gastroenterology and Hepatology, Singapore, Singapore.

INTRODUCTION Although EUS features and criteria have been described in chronic pancreatitis, challenges remain with inter-operator variability and ease of adoption. AIMS The aim of the study was to define and validate EUS features of chronic pancreatitis in a multi-center prospective study in Asia. METHOD The study was conducted in 2 phases. Read More

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http://dx.doi.org/10.1055/a-1217-3112DOI Listing

Air quality during the COVID-19: PM analysis in the 50 most polluted capital cities in the world.

Environ Pollut 2020 Jul 3;266(Pt 1):115042. Epub 2020 Jul 3.

Universidad EAN, Bogotá, Colombia. Electronic address:

On December 31, 2019, the Chinese authorities reported to the World Health Organization (WHO) the outbreak of a new strain of coronavirus that causes a serious disease in the city of Wuhan, China. This outbreak was classified as SARS-CoV2 and is the cause of the COVID-19 disease. On March 11, 2020, the WHO declares it a Pandemic and today it is considered the greatest challenge in global health that humanity has faced since World War II and it is estimated that between 40 and 60% of the population worldwide will catch the virus. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.115042DOI Listing

Proteogenomics of Non-smoking Lung Cancer in East Asia Delineates Molecular Signatures of Pathogenesis and Progression.

Cell 2020 Jul;182(1):226-244.e17

Institute of Chemistry, Academia Sinica, Taipei, Taiwan; Department of Chemistry, National Taiwan University, Taipei, Taiwan. Electronic address:

Lung cancer in East Asia is characterized by a high percentage of never-smokers, early onset and predominant EGFR mutations. To illuminate the molecular phenotype of this demographically distinct disease, we performed a deep comprehensive proteogenomic study on a prospectively collected cohort in Taiwan, representing early stage, predominantly female, non-smoking lung adenocarcinoma. Integrated genomic, proteomic, and phosphoproteomic analysis delineated the demographically distinct molecular attributes and hallmarks of tumor progression. Read More

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http://dx.doi.org/10.1016/j.cell.2020.06.012DOI Listing

Baicalin regulates macrophages polarization and alleviates myocardial ischaemia/reperfusion injury via inhibiting JAK/STAT pathway.

Pharm Biol 2020 Dec;58(1):655-663

Department of Cardiac Surgery, Wuhan Asia Heart Hospital, Wuhan, P.R. China.

Context: Baicalin is an active compound which demonstrates cardioprotection effects against myocardial ischaemia/reperfusion injury (MI/RI).

Objective: To investigate how baicalin protects against myocardial injury and to explore its potential mechanism. We hypothesized that baicalin-modulated macrophages change from M1 (pro-inflammatory subset) to M2 (anti-inflammatory subset) under I/R stress. Read More

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http://dx.doi.org/10.1080/13880209.2020.1779318DOI Listing
December 2020

The Asian Association for the Study of Diabetes (AASD): The first ten years and the next ten years.

J Diabetes Investig 2020 Jul 10. Epub 2020 Jul 10.

The Office of the Asian Association for the Study of Diabetes, Tokyo, Japan.

The global diabetes population today is 433 million (9.3% of the population aged 20-79 years), and is expected to grow to 700 million (10.9% of the population aged 20-79) by 2045 without effective countermeasures . Read More

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http://dx.doi.org/10.1111/jdi.13353DOI Listing

Dispersal patterns of an introduced wild bee, Megachile sculpturalis Smith, 1853 (Hymenoptera: Megachilidae) in European alpine countries.

PLoS One 2020 10;15(7):e0236042. Epub 2020 Jul 10.

Institute for Integrative Nature Conservation Research, University of Natural Resources and Life Sciences Vienna (BOKU), Vienna, Austria.

Biodiversity monitoring programs are the baseline of species abundancy studies, which in case of introduced species are especially critical. Megachile sculpturalis Smith, 1853 native to Eastern-Asia, constitutes the first ever recorded wild bee species accidently introduced in Europe. Since its first discovery in 2008, M. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236042PLOS

Isolated systolic hypertension and 29-year cardiovascular mortality risk in Japanese adults aged 30--49 years.

J Hypertens 2020 Jul 6. Epub 2020 Jul 6.

Department of Public Health.

Objective: The prognostic implication of isolated systolic hypertension (ISH), defined as SBP at least 140 mmHg and DBP less than 90 mmHg, among young-to-middle-aged adults remains controversial. We examined the association of ISH with cardiovascular disease (CVD) risk in adults aged 30-49 years.

Methods: In a prospective cohort of representative Japanese general populations from the NIPPON DATA80 (1980-2009), we studied 4776 participants (mean age, 39. Read More

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http://dx.doi.org/10.1097/HJH.0000000000002533DOI Listing

Modified V-Y Myocutaneous Flap With Vascular Pedicle for the Repair of Maxillofacial Skin Defects.

J Craniofac Surg 2020 Jul 1. Epub 2020 Jul 1.

Department of Stomatology, the Third Xiangya Hospital, Central South University.

Objective: It is challenging to repair postoperative defect caused by skin tumor resection on the maxillofacial, which not only affects appearance but also impairs functions. To better repair skin defect on the maxillofacial, the application value of V-Y vascular myocutaneous flap was introduced in our study.

Methods: Between June 2011 and December 2018, 16 patients with maxillofacial skin tumors who received extensive resection were enrolled in our study. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006745DOI Listing

Gender Differences in Cancer Patients' Preferences for Truth-Telling in Taiwan.

Cancer Nurs 2020 Jul 8. Epub 2020 Jul 8.

Author Affiliations: School of Nursing, Chang Gung University, Taoyuan, Taiwan (Ms. Chen and Dr Tang); Psycho-Oncology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan (Dr Fujimori); and Department of Hematology-Oncology, Chang Gung Memorial Hospital, Linkou, Taiwan (Drs Wang and Tang).

Background: There is a lack of studies investigating gender differences in cancer truth-telling, especially from the Asia Pacific countries.

Objective: The aim of this study was to compare preferences for cancer truth-telling between male and female cancer patients in Taiwan.

Methods: We used a quantitative cross-sectional design. Read More

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http://dx.doi.org/10.1097/NCC.0000000000000856DOI Listing

Tobacco Industry Fingerprints on Delaying Implementation of Pictorial Health Warnings in the Western Pacific.

Asian Pac J Cancer Prev 2020 Jul 1;21(S1):23-25. Epub 2020 Jul 1.

Southeast Asia Tobacco Control Alliance, Bangkok, Thailand.

Objective: This case series describes tobacco industry tactics and strategies used to interfere, derail, delay, and weaken the development of effective health warning regulations in Malaysia, Cambodia, the Philippines, and Hong Kong.

Methods: A historical review of official reports, news articles, and gray literature was undertaken to identify tobacco industry tactics and strategies to hamper government efforts in implementing stronger pictorial health warning regulations in four Asian jurisdictions (Cambodia, Hong Kong, Malaysia, and the Philippines).

Results: Nineteen countries/jurisdictions in the WHO Western Pacific region currently require pictorial health warnings on cigarette packs, including some of the world's largest, in line with the WHO Framework Convention on Tobacco Control Article 11 Guidelines. Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.S1.23DOI Listing

Improving Information to Enable Effective Tobacco Control Intervention and Measure Progress Over Time: The Cambodia Country Experience.

Asian Pac J Cancer Prev 2020 Jul 1;21(S1):5-8. Epub 2020 Jul 1.

(Former) South East Asia Tobacco Control Alliance (SEATCA), Bangkok, Thailand.

Tobacco is a leading cause of noncommunicable diseases (NCDs) which kill about 41 million people each year. Of these, 15 million die prematurely between the ages of 30 and 69 years, most of which occur in low- and middle-income countries (LMICs). The adoption of the Sustainable Development Goals and their targets under the 2030 Agenda for Sustainable Development provides a new impetus for countries to accelerate tobacco control efforts as they specifically call for strengthening implementation of the World Health Organization (WHO) Framework Convention on Tobacco Control and striving to achieve a one-third reduction in premature deaths from NCDs. Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.S1.5DOI Listing

Sacrocolpopexy tends to be superior to transvaginal mesh surgery.

BJOG 2020 Jul 10. Epub 2020 Jul 10.

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

The use of synthetic mesh prostheses to treat pelvic organ prolapse (POP) remains highly controversial. Despite complete restriction on vaginally placed mesh in Australia and New Zealand (2017), the UK (2018), and the USA (2019), transvaginal mesh (TVM) prolapse repair remain widely in many countries, including China and most of East Asia. Sacrocolpopexy (SC) is widely considered as the gold-standard for surgical correction of vaginal vault prolapse. Read More

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http://dx.doi.org/10.1111/1471-0528.16407DOI Listing

Impact of the coronavirus disease 2019 (COVID-19) pandemic on pediatric oncology care in the Middle East, North Africa, and West Asia Region: A report from the Pediatric Oncology East and Mediterranean (POEM) Group.

Cancer 2020 Jul 10. Epub 2020 Jul 10.

Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, Tennessee.

Background: Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated.

Methods: A 34-item survey focusing on barriers to pediatric oncology management during the COVID-19 pandemic was distributed to heads of pediatric oncology units within the Pediatric Oncology East and Mediterranean (POEM) collaborative group, from the Middle East, North Africa, and West Asia. Read More

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http://dx.doi.org/10.1002/cncr.33075DOI Listing

Enhanced Bone Formation in Osteoporotic Mice by a Novel Transplant Combined with Adipose-derived Stem Cells and Platelet-rich Fibrin Releasates.

Cell Transplant 2020 Jan-Dec;29:963689720927398

School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.

Osteoporotic fracture is the main complication of osteoporosis (OP) and accounts for millions of injuries annually. Local intervention by intra-marrow injection has been a good option for preventing osteoporotic bone loss when the osteoporotic femoral fracture has been treated. In this study, tail vein transplantations were examined to evaluate the cell-based therapeutic approach for treating OP with adipose-derived stem cells (ADSCs) and platelet-rich fibrin releasates (PRFr) in an ovariectomized (OVX) mice model. Read More

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http://dx.doi.org/10.1177/0963689720927398DOI Listing

International traditional Chinese medicine guideline for diagnostic and treatment principles of diabetes.

Ann Palliat Med 2020 Jul 10. Epub 2020 Jul 10.

Department of Endocrinology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Diabetes mellitus (DM) was one of the most severe public health problems that affected nearly 463 million adults around the world. In addition to insulin and oral hypoglycemic agents, traditional Chinese medicine (TCM) was an effective alternative therapy for diabetes and its complications, and it had been widely used in the Pan-Pacific region, especially in Southeast Asia, however, TCM lacked specialized standards of care for DM in the past, which limited the TCM clinical efficacy of diabetes. Since March 2017, the Endocrinology Committee of World Federation of Chinese Medicine Societies (WFCMS) had invited experts in diabetes, TCM, and international standard setting to work with TCM endocrinologists from the Guideline Development Committee to review the TCM clinical research evidence related to the prevention and treatment of diabetes over the previous 14 years. Read More

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http://dx.doi.org/10.21037/apm-19-271DOI Listing

Clinical Practice Guideline Recommendation on the Use of Low Intensity Extracorporeal Shock Wave Therapy and Low Intensity Pulsed Ultrasound Shock Wave Therapy to Treat Erectile Dysfunction: The Asia-Pacific Society for Sexual Medicine Position Statement.

World J Mens Health 2020 Jun 2. Epub 2020 Jun 2.

Department of Urology and Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.

Published literature shows low intensity extracorporeal shock wave therapy (LIESWT) and low intensity pulsed ultrasound (LIPUS) therapy to improve erectile function and penile hemodynamic by inducing neovascularisation and promoting tissue regeneration. Key opinion leaders across the Asia Pacific region attended the recent biennial meeting of the Asia Pacific Society for Sexual Medicine in Australia, and presented the current evidence on LIESWT and LIPUS for erectile dysfunction (ED). The clinical findings were internally discussed, and the quality of evidence was graded based on the Oxford Centre for Evidence-Based Medicine recommendations. Read More

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http://dx.doi.org/10.5534/wjmh.200077DOI Listing

Molecular detection of Rickettsia species and host associations of Laelaps mites (Acari: Laelapidae) in Taiwan.

Exp Appl Acarol 2020 Jul 9. Epub 2020 Jul 9.

Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan.

Various rickettsiae have recently been detected in Laelaps mites (Acari: Laelapidae), which are common ectoparasites of rodents; however, investigations on this topic remain very scarce, particularly in Asia. In the present study, shrews and rodents were trapped from 2006 to 2010 in eight lowland regions of Taiwan (< 500 m in elevation) to collect associated Laelaps mites, from which Rickettsia-a group of emerging pathogens-were detected and identified by assaying the gltA and ompB genes. A total of 853 Laelaps mites of at least four species were collected from a sample of 1004 small mammals that included one shrew and 10 rodent species. Read More

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http://dx.doi.org/10.1007/s10493-020-00522-1DOI Listing

Erratum to rapid advice guidelines for management of children with COVID-19.

Ann Transl Med 2020 Jun;8(12):807

National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.

[This corrects the article DOI: 10.21037/atm-20-3754.]. Read More

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http://dx.doi.org/10.21037/atm-2020-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333161PMC

A Changing Paradigm for the Treatment of Intermediate-Stage Hepatocellular Carcinoma: Asia-Pacific Primary Liver Cancer Expert Consensus Statements.

Liver Cancer 2020 Jun 13;9(3):245-260. Epub 2020 May 13.

Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.

The Asia-Pacific Primary Liver Cancer Expert (APPLE) Consensus Statement on the treatment strategy for patients with intermediate-stage hepatocellular carcinoma (HCC) was established on August 31, 2019, in Sapporo, Hokkaido during the 10th Annual APPLE Meeting. This manuscript summarizes the international consensus statements developed at APPLE 2019. Transarterial chemoembolization (TACE) is the only guideline-recommended global standard of care for intermediate-stage HCC. Read More

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http://dx.doi.org/10.1159/000507370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325125PMC

Looks can be deceiving: the deceptive milkcaps (, Russulaceae) exhibit low morphological variance but harbour high genetic diversity.

IMA Fungus 2019 18;10:14. Epub 2019 Sep 18.

Department of Biology, Research group Mycology, Ghent University, K.L. Ledeganckstraat 35, 9000 Ghent, Belgium.

The ectomycorrhizal genus is known to contain many species complexes, consisting of morphologically very similar species, which can be considered cryptic or pseudocryptic. In this paper, a thorough molecular study is performed of the clade around (originally described by Peck from North America) or the deceptive milkcaps. Even though most collections were identified as , the clade is shown to contain at least 15 species, distributed across Asia and America, indicating that the clade represents a species complex. Read More

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http://dx.doi.org/10.1186/s43008-019-0017-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325672PMC
September 2019

A pan-specific antiserum produced by a novel immunization strategy shows a high spectrum of neutralization against neurotoxic snake venoms.

Sci Rep 2020 Jul 9;10(1):11261. Epub 2020 Jul 9.

Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia.

Snakebite envenomation is a neglected tropical disease of high mortality and morbidity largely due to insufficient supply of effective and affordable antivenoms. Snake antivenoms are mostly effective against the venoms used in their production. It is thus crucial that effective and affordable antivenom(s) with wide para-specificity, capable of neutralizing the venoms of a large number of snakes, be produced. Read More

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http://dx.doi.org/10.1038/s41598-020-66657-8DOI Listing

Electrocardiographic changes predate Parkinson's disease onset.

Sci Rep 2020 Jul 9;10(1):11319. Epub 2020 Jul 9.

Division of Occupational and Environmental Medicine, University of California-San Francisco, San Francisco, CA, USA.

Autonomic nervous system involvement precedes the motor features of Parkinson's disease (PD). Our goal was to develop a proof-of-concept model for identifying subjects at high risk of developing PD by analysis of cardiac electrical activity. We used standard 10-s electrocardiogram (ECG) recordings of 60 subjects from the Honolulu Asia Aging Study including 10 with prevalent PD, 25 with prodromal PD, and 25 controls who never developed PD. Read More

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http://dx.doi.org/10.1038/s41598-020-68241-6DOI Listing

Management of nonpainful supernumerary phantom limbs after incomplete spinal cord injury with visual-tactile feedback therapy: a case report.

Spinal Cord Ser Cases 2020 Jul 9;6(1):62. Epub 2020 Jul 9.

Department of Physical Medicine and Rehabilitation, Rutgers-New Jersey Medical School, Newark, NJ, USA.

Introduction: Supernumerary phantom limb (SPL) is an uncommon phantom sensation where the patient experiences the illusory presence of one or more limbs in addition to their existing limbs. SPL after a spinal cord injury (SCI) is rare with few documented cases. There is minimal treatment guidance available, with some reports of visual-tactile feedback therapy used to manage SPL. Read More

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http://dx.doi.org/10.1038/s41394-020-0312-7DOI Listing

Correction to: The influence of corruption and governance in the delivery of frontline health care services in the public sector: a scoping review of current and future prospects in low and middle-income countries of south and south-east Asia.

BMC Public Health 2020 Jul 9;20(1):1082. Epub 2020 Jul 9.

BRAC James P. Grant BRAC School of Public Health, BRAC University, 5th Floor (Level-6), icddrb Building, 68 ShahidTajuddin Ahmed Sarani, Mohakhali, Dhaka, 1212, Bangladesh.

An amendment to this paper has been published and can be accessed via the original article. Read More

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http://dx.doi.org/10.1186/s12889-020-09197-0DOI Listing

Draft genome sequence of the oomycete Pythium destruens strain ATCC 64221 from a horse with pythiosis in Australia.

BMC Res Notes 2020 Jul 9;13(1):329. Epub 2020 Jul 9.

Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Objectives: Genome sequences are a vital resource for accelerating the biological exploration of an organism of interest. Pythium destruens (a synonym of Pythium insidiosum) causes a difficult-to-treat infectious disease called pythiosis worldwide. Detection and management of pythiosis are challenging. Read More

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http://dx.doi.org/10.1186/s13104-020-05168-1DOI Listing

A review of Saurauia roxburghii Wall. (Actinidiacaea) as a traditional medicinal plant, its phytochemical study and therapeutic potential.

Mini Rev Med Chem 2020 Jul 9. Epub 2020 Jul 9.

Molecular Modeling Drug-design and Discovery Laboratory, Pharmacology Research Division, BCSIR Laboratories Chattogram, Bangladesh Council of Scientific and Industrial Research, Chattogram. Bangladesh.

Ethnopharmacological Relevance: Saurauia roxburghii Wall. is an interesting plant, found growing chiefly along the eastern and south-eastern countries of Asia. The various ethnic groups of these regions use the plant as a medication for relieving a wide spectrum of diseases and conditions, including indigestion, boils, fever, gout, piles, eczema, asthma, ulcers, bronchitis, epilepsy, and hepatitis B. Read More

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http://dx.doi.org/10.2174/1389557520666200709175138DOI Listing

Cilostazol for Secondary Prevention of Stroke and Cognitive Decline: Systematic Review and Meta-Analysis.

Stroke 2020 Jul 10:STROKEAHA120029454. Epub 2020 Jul 10.

Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, United Kingdom (J.P.A., P.M.B.).

Background And Purpose: Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be beneficial in preventing small vessel disease progression.

Methods: A systematic review and meta-analysis of unconfounded randomized controlled trials of cilostazol to prevent stroke, cognitive decline, or radiological small vessel disease lesion progression. Read More

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http://dx.doi.org/10.1161/STROKEAHA.120.029454DOI Listing

A SNP-Based Genome-Wide Association Study to Mine Genetic Loci Associated to Salinity Tolerance in Mungbean ( L.).

Genes (Basel) 2020 Jul 7;11(7). Epub 2020 Jul 7.

World Vegetable Center, Biotechnology and Molecular Breeding, Shanhua, Tainan 74199, Taiwan.

Mungbean ( (L.) R. Wilzeck var. Read More

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http://dx.doi.org/10.3390/genes11070759DOI Listing

Health Literacy of Osteoporosis Risks among Caregivers Serving in Disability Care Facilities.

Int J Environ Res Public Health 2020 Jul 7;17(13). Epub 2020 Jul 7.

Institute of Long-Term Care, Mackay Medical College, New Taipei City 235, Taiwan.

Osteoporosis is a global public health issue and its consequent effects are a growing concern worldwide. Caregivers generally experience occupational physical ailments and they have less of a tendency to engage in preventive health behaviors, leading them to be in a higher risk group for osteoporosis. This study aims to present a general profile of health literacy related to osteoporosis risks and identify its associated factors among disability institutional caregivers. Read More

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http://dx.doi.org/10.3390/ijerph17134903DOI Listing

Banhasasim-Tang Attenuates Lipopolysaccharide-Induced Cognitive Impairment by Suppressing Neuroinflammation in Mice.

Nutrients 2020 Jul 7;12(7). Epub 2020 Jul 7.

Korean Medicine (KM)-Application Center, Korea Institute of Oriental Medicine, Daegu 41062, Korea.

Banhasasim-tang (BHS) is an herbal medicine that has been widely used in East Asia to treat various symptoms associated with upper abdomen swelling. BHS has not been studied previously for neuroinflammation or cognitive disorder. Here, we use a lipopolysaccharide (LPS) model to investigate the effects and mechanisms of BHS in neuroinflammation and cognitive impairment of mice. Read More

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http://dx.doi.org/10.3390/nu12072019DOI Listing

Effects of Paper Mulberry Silage on the Milk Production, Apparent Digestibility, Antioxidant Capacity, and Fecal Bacteria Composition in Holstein Dairy Cows.

Animals (Basel) 2020 Jul 7;10(7). Epub 2020 Jul 7.

State Key Laboratory of Animal Nutrition, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agriculture University, Beijing 100193, China.

Paper mulberry (; PM) is an excellent and extensive type of roughage in Asia. This study aimed to evaluate the effects of PM silage on the milk production, apparent digestibility, antioxidant capacity, and fecal bacteria composition in Holstein dairy cows. Forty-five lactating Holstein dairy cows with a similar milk yield and parity were selected and randomly assigned to three groups. Read More

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http://dx.doi.org/10.3390/ani10071152DOI Listing

Towards a Sustainable One Health Approach to Crimean-Congo Hemorrhagic Fever Prevention: Focus Areas and Gaps in Knowledge.

Trop Med Infect Dis 2020 Jul 7;5(3). Epub 2020 Jul 7.

Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.

Crimean-Congo hemorrhagic fever virus (CCHFV) infection is identified in the 2018 World Health Organization Research and Development Blueprint and the National Institute of Allergy and Infectious Diseases (NIH/NIAID) priority A list due to its high risk to public health and national security. Tick-borne CCHFV is widespread, found in Europe, Asia, Africa, the Middle East, and the Indian subcontinent. It circulates between ticks and several vertebrate hosts without causing overt disease, and thus can be present in areas without being noticed by the public. Read More

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http://dx.doi.org/10.3390/tropicalmed5030113DOI Listing

Physical Properties of Carboxymethyl Cellulose from Palm Bunch and Bagasse Agricultural Wastes: Effect of Delignification with Hydrogen Peroxide.

Polymers (Basel) 2020 Jul 7;12(7). Epub 2020 Jul 7.

School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.

The aim of this work was to synthesize carboxymethyl cellulose (CMC) and produce CMC films from the cellulose of palm bunch and bagasse agricultural waste. The effect of various amounts of HO (0-40% /) during delignification on the properties of cellulose, CMC, and CMC films was studied. As the HO content increased, yield and the lignin content of the cellulose from palm bunch and bagasse decreased, whereas lightness () and whiteness index (WI) increased. Read More

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http://dx.doi.org/10.3390/polym12071505DOI Listing

Cytotoxic and Anti-inflammatory Terpenoids from the Whole Plant of Vaccinium emarginatum.

Planta Med 2020 Jul 9. Epub 2020 Jul 9.

Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung, Taiwan.

Two new Δ ursene-type triterpenoid coumaroyl esters (1: and 2: ), one new Δ isopimarane-type diterpenoid glycoside (20: ), and two new irido--lactone-type iridoids (21: and 22: ), together with 17 known pentacyclic triterpenoids (3:  - 19: ), were isolated during the phytochemical investigation of a methanol extract of the whole plant of . Their structures were determined by detailed analysis of standard spectroscopic data (MS, IR, 1D, and 2D NMR) and comparison with data of known analogs. The isolates were evaluated for their cytotoxicity against the PC-3 and Du145 prostate cancer cell lines (as assessed by an MTT cell proliferation assay), as well as for their anti-inflammatory activity via the inhibition of nitric oxide production in lipopolysaccharide-induced murine macrophage RAW 264. Read More

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http://dx.doi.org/10.1055/a-1192-6225DOI Listing

Effects of Vitamin D Supplementation on General and Central Obesity: Results from 20 Randomized Controlled Trials Involving Apparently Healthy Populations.

Ann Nutr Metab 2020 Jul 9:1-12. Epub 2020 Jul 9.

Public Health and Preventive Medicine Teaching and Research Center, Henan University of Chinese Medicine, Zhengzhou, China,

Background: The obesity pandemic has been paralleled by a high prevalence of vitamin D deficiency (VDD). There is growing epidemiological evidence linking low vitamin D status with obesity events. In addition, observational studies also show that obesity may increase the risk of VDD. Read More

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http://dx.doi.org/10.1159/000507418DOI Listing

Efficacy of favipiravir (T-705) against Crimean-Congo hemorrhagic fever virus infection in cynomolgus macaques.

Antiviral Res 2020 Jul 6:104858. Epub 2020 Jul 6.

Rocky Mountain Laboratories, NIAID/NIH, Hamilton, MT, USA.

Crimean-Congo hemorrhagic fever virus (CCHFV) is a widely distributed hemorrhagic fever virus found throughout Eastern Europe, Africa, the Middle East and Asia. It is spread through bites from infected ticks, animal husbandry and can also be acquired in the healthcare setting during care of infected patients. In humans, CCHFV can cause a sudden onset of a non-specific febrile illness that can rapidly progress to severe hemorrhagic manifestations. Read More

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http://dx.doi.org/10.1016/j.antiviral.2020.104858DOI Listing

A simplified, combined protocol versus standard treatment for acute malnutrition in children 6-59 months (ComPAS trial): A cluster-randomized controlled non-inferiority trial in Kenya and South Sudan.

PLoS Med 2020 Jul 9;17(7):e1003192. Epub 2020 Jul 9.

Department of Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Background: Malnutrition underlies 3 million child deaths worldwide. Current treatments differentiate severe acute malnutrition (SAM) from moderate acute malnutrition (MAM) with different products and programs. This differentiation is complex and costly. Read More

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http://dx.doi.org/10.1371/journal.pmed.1003192DOI Listing

A scientometric analysis of birth cohorts in South Asia: Way forward for Pakistan.

PLoS One 2020 9;15(7):e0235385. Epub 2020 Jul 9.

Institute of Psychology, Health and Society, University of Liverpool, Liverpool, United Kingdom.

The present study aims to: a) systematically map the of birth cohort studies from the South Asian region b) examine the major research foci and landmark contributions from these cohorts using reproducible scientometric techniques and c) offer recommendations on establishing new birth cohorts in Pakistan, building upon the strengths, weaknesses and gaps of previous cohorts. Bibliographic records for a total of 260 articles, published during through December 2018, were retrieved from the Web of Science (core database). All data were analysed using Microsoft Excel (2013), Web of Science platform and CiteSpace. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235385PLOS

Global socio-economic losses and environmental gains from the Coronavirus pandemic.

PLoS One 2020 9;15(7):e0235654. Epub 2020 Jul 9.

Integrated Sustainability Analysis, School of Physics, The University of Sydney, Sydney, NSW, Australia.

On 3 April 2020, the Director-General of the WHO stated: "[COVID-19] is much more than a health crisis. We are all aware of the profound social and economic consequences of the pandemic (WHO, 2020)". Such consequences are the result of counter-measures such as lockdowns, and world-wide reductions in production and consumption, amplified by cascading impacts through international supply chains. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235654PLOS

Relationship between Uveitis and Thyroid Disease: A 13-Year Nationwide Population-based Cohort Study in Taiwan.

Ocul Immunol Inflamm 2020 Jul 9:1-7. Epub 2020 Jul 9.

Department of Ophthalmology, China Medical University Hospital, China Medical University , Taichung, Taiwan.

Purpose: To investigate whether patients with thyroid disease are at increased risk of uveitis.

Methods: Data was collected from the Taiwan National Health Insurance system and included patients newly diagnosed with thyroid disease from 2000 to 2012. The endpoint of interest was a diagnosis of uveitis. Read More

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http://dx.doi.org/10.1080/09273948.2020.1762899DOI Listing

Understanding of Young People About COVID-19 During Early Outbreak in Indonesia.

Asia Pac J Public Health 2020 Jul 9:1010539520940933. Epub 2020 Jul 9.

Faculty of Medicine, Pelita Harapan University, Tangerang, Banten, Indonesia.

To control the spread of COVID-19 transmission, Indonesia government has broadcasted information about the pandemic. The aim of this study is to evaluate the understanding of young people, about COVID-19 during the early outbreak in Indonesia. An online-based cross-sectional data collection was conducted from adolescents aged 10 to 25 years, based on 10 questions regarding general COVID-19 information. Read More

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http://dx.doi.org/10.1177/1010539520940933DOI Listing

Validation: The Use of Google Trends as an Alternative Data Source for COVID-19 Surveillance in Indonesia.

Asia Pac J Public Health 2020 Jul 9:1010539520940896. Epub 2020 Jul 9.

Universitas Gadjah Mada, Yogyakarta, Indonesia.

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http://dx.doi.org/10.1177/1010539520940896DOI Listing

Feco-Oral Transmission of SARS-CoV-2: A Review.

Asia Pac J Public Health 2020 Jul 9:1010539520940931. Epub 2020 Jul 9.

Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1177/1010539520940931DOI Listing

COVID-19 and hypertension-evidence and practical management: Guidance from the HOPE Asia Network.

J Clin Hypertens (Greenwich) 2020 Jul 9. Epub 2020 Jul 9.

Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

There are several risk factors for worse outcomes in patients with coronavirus 2019 disease (COVID-19). Patients with hypertension appear to have a poor prognosis, but there is no direct evidence that hypertension increases the risk of new infection or adverse outcomes independent of age and other risk factors. There is also concern about use of renin-angiotensin system (RAS) inhibitors due to a key role of angiotensin-converting enzyme 2 receptors in the entry of the SARS-CoV-2 virus into cells. Read More

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http://dx.doi.org/10.1111/jch.13917DOI Listing

Efficacy and safety of peficitinib in rheumatoid arthritis.

Authors:
Yuko Kaneko

Mod Rheumatol 2020 Jul 9:1-15. Epub 2020 Jul 9.

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

Peficitinib is a Janus kinase (JAK) inhibitor, newly developed and approved in Japan. In contrast to other JAK inhibitors, it is a unique pan-JAK inhibitor, demonstrating inhibition of all JAKs. In patients with rheumatoid arthritis with an inadequate response to previous disease-modifying anti-rheumatic drugs, the efficacy of peficitinib (100 mg and 150 mg) has been confirmed with a comparison to placebo in Phase 2b and 3 trials conducted in Asia. Read More

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http://dx.doi.org/10.1080/14397595.2020.1794103DOI Listing

Population genetics of wild Macaca fascicularis with low-coverage shotgun sequencing of museum specimens.

Am J Phys Anthropol 2020 Jul 8. Epub 2020 Jul 8.

University of Illinois Urbana-Champaign, Urbana, Illinois, USA.

Objectives: Long-tailed macaques (Macaca fascicularis) are widely distributed throughout the mainland and islands of Southeast Asia, making them a useful model for understanding the complex biogeographical history resulting from drastic changes in sea levels throughout the Pleistocene. Past studies based on mitochondrial genomes (mitogenomes) of long-tailed macaque museum specimens have traced their colonization patterns throughout the archipelago, but mitogenomes trace only the maternal history. Here, our objectives were to trace phylogeographic patterns of long-tailed macaques using low-coverage nuclear DNA (nDNA) data from museum specimens. Read More

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http://dx.doi.org/10.1002/ajpa.24099DOI Listing

Detection of New Delhi Metallo-β-lactamase 1 and Cephalosporin Resistance Genes Among Carbapenem-Resistant Enterobacteriaceae in Water Bodies Adjacent to Hospitals in India.

Curr Microbiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Aquatic Animal Health Management, Kerala University of Fisheries and Ocean Studies, Kochi, Kerala, India.

The prevalence of carbapenem resistance among bacterial isolates from selected water bodies receiving hospital effluents and adjoining aquaculture farms in Kerala, India, was studied. Klebsiella pneumoniae followed by Escherichia coli, Klebsiella oxytoca, Enterobacter aerogenes and Acinetobacter baumannii were the predominant isolates. Antibiotic sensitivity of these isolates was determined by Kirby-Bauer disc diffusion method. Read More

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http://dx.doi.org/10.1007/s00284-020-02107-yDOI Listing

Modeling smallholder livestock herders' intentions to adopt climate smart practices: An extended theory of planned behavior.

Environ Sci Pollut Res Int 2020 Jul 8. Epub 2020 Jul 8.

Department of Economics, Government College University, Faisalabad, 38000, Pakistan.

Climate change is persistently causing adverse effects to the agriculture sector of developing countries, specifically in Asia. Pakistan is no exception to this effect and is ranked among the top 10 countries, which are most vulnerable to climate change. A huge upcoming challenge is to sustain an equilibrium among production and environmental protection. Read More

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http://dx.doi.org/10.1007/s11356-020-09652-wDOI Listing
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