807,358 results match your criteria Asia Pacific Education Review[Journal]


The effect of Xiang-Sha-Liu-Jun-Zi tang (XSLJZT) on irritable bowel syndrome: A randomized, double-blind, placebo-controlled trial.

J Ethnopharmacol 2019 Apr 19:111889. Epub 2019 Apr 19.

Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan; Chinese Medicine Research Center, China Medical University, Taichung 40402, Taiwan; Research Center for Chinese Medicine and Acupuncture, China Medical University, Taichung 40402, Taiwan; Department of Chinese Medicine, China Medical University Hospital, Taichung 40447, Taiwan. Electronic address:

Background: Irritable bowel syndrome (IBS) is characterized by chronic, recurrent abdominal pain or abdominal discomfort and changes in defecation habits. Xiang-Sha-Liu-Jun-Zi tang (XSLJZT) is a traditional Chinese medical formula that can modulate gastrointestinal disturbance.

Purpose: To investigate the therapeutic effect of XSLJZT on IBS. Read More

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http://dx.doi.org/10.1016/j.jep.2019.111889DOI Listing

Genome-wide annotation and comparative analysis of cuticular protein genes in the noctuid pest Spodoptera litura.

Insect Biochem Mol Biol 2019 Apr 19. Epub 2019 Apr 19.

State Key Laboratory of Silkworm Genome Biology, Biological Science Research Center, Southwest University, Chongqing, 400716, China; Chongqing Key Laboratory of Sericultural Science, Chongqing Engineering and Technology Research Center for Novel Silk Materials, Southwest University, Chongqing, 400716, China. Electronic address:

Insect cuticle is considered an adaptable and versatile building material with roles in the construction and function of exoskeleton. Its physical properties are varied, as the biological requirements differ among diverse structures and change during the life cycle of the insect. Although the bulk of cuticle consists basically of cuticular proteins (CPs) associated with chitin, the degree of cuticular sclerotization is an important factor in determining its physical properties. Read More

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http://dx.doi.org/10.1016/j.ibmb.2019.04.012DOI Listing

Temporal, spatial and household dynamics of Typhoid fever in Kasese district, Uganda.

PLoS One 2019 22;14(4):e0214650. Epub 2019 Apr 22.

Department of Biosecurity Ecosystems and Veterinary Public Health, Makerere University, Kampala, Uganda.

Typhoid fever affects 21 million people globally, 1% of whom succumb to the disease. The social, economic and public health consequences of this disease disproportionately affect people in Africa and Asia. In order to design context specific prevention strategies, we need to holistically characterise outbreaks in these settings. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214650PLOS

Center of pressure progression patterns during level walking in adolescents with idiopathic scoliosis.

PLoS One 2019 22;14(4):e0212161. Epub 2019 Apr 22.

Department of Creative Product Design, Asia University, Taichung, Taiwan.

The purpose of this study was to determine whether functional walking performance measured with Timed Up-and-Go (TUG) and center of pressure (CoP) progression pattern is different across adolescents with various curve severity of idiopathic scoliosis (IS). The CoP coordinates during a stance phase for self-paced level walking between adolescent with three different severities of IS (mild IS, moderate IS, and severe IS) and age-matched normal subjects were measured with foot pressure measurement. The average data of three trials were compared among groups with repeated measure analysis of variance. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212161PLOS
April 2019
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Projecting impacts of global climate and land-use scenarios on plant biodiversity using compositional-turnover modelling.

Glob Chang Biol 2019 Apr 22. Epub 2019 Apr 22.

CSIRO Land and Water, Building 101, Black Mountain Laboratories, Clunies Ross St., Canberra, ACT, 2601, Australia.

Nations have committed to ambitious conservation targets in response to accelerating rates of global biodiversity loss. Anticipating future impacts is essential to inform policy decisions for achieving these targets, but predictions need to be of sufficiently high spatial resolution to forecast the local effects of global change. As part of the intercomparison of biodiversity and ecosystem services models of the IPBES, we present a fine-resolution assessment of trends in the persistence of global plant biodiversity. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/gcb.14663
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http://dx.doi.org/10.1111/gcb.14663DOI Listing
April 2019
1 Read

Prognostic significance of nuclear Yes-associated protein 1 in patients with nonsmall cell lung cancer: A systematic review and meta-analysis.

Medicine (Baltimore) 2019 Apr;98(16):e15069

Lung Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.

Background: Nuclear Yes-associated protein 1 (YAP1) has often been regarded as an adverse prognostic indicator in various tumors. Recent studies have associated YAP1 with unfavorable prognosis in nonsmall cell lung cancer (NSCLC). However, due to small sample sizes, the prognostic value of nuclear YAP1 in NSCLC patients is not well understood. Read More

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http://dx.doi.org/10.1097/MD.0000000000015069DOI Listing

Left atrial appendage closure with WATCHMAN in Asian patients: 2 year outcomes from the WASP registry.

Int J Cardiol Heart Vasc 2019 Jun 9;23:100358. Epub 2019 Apr 9.

National Heart Institute, Kuala Lumpur, Malaysia.

Background: Left atrial appendage closure is a non-pharmacological alternative for stroke prevention in high-risk non-valvular atrial fibrillation patients, but has not been widely studied in Asian patients. The prospective WASP registry assessed real-world outcomes for patients undergoing WATCHMAN implant in the Asia-Pacific region.

Methods: Data were collected from consecutive patients across 9 centres. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23529067193002
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http://dx.doi.org/10.1016/j.ijcha.2019.100358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458488PMC
June 2019
1 Read

Balance of Emission and Dynamical Controls on Ozone During the Korea-United States Air Quality Campaign From Multiconstituent Satellite Data Assimilation.

J Geophys Res Atmos 2019 Jan 3;124(1):387-413. Epub 2019 Jan 3.

Atmospheric Chemistry Observations and& Modeling (ACOM) Laboratory National Center for Atmospheric Research Boulder CO USA.

Global multiconstituent concentration and emission fields obtained from the assimilation of the satellite retrievals of ozone, CO, NO, HNO, and SO from the Ozone Monitoring Instrument (OMI), Global Ozone Monitoring Experiment 2, Measurements of Pollution in the Troposphere, Microwave Limb Sounder, and Atmospheric Infrared Sounder (AIRS)/OMI are used to understand the processes controlling air pollution during the Korea-United States Air Quality (KORUS-AQ) campaign. Estimated emissions in South Korea were 0.42 Tg N for NO and 1. Read More

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http://dx.doi.org/10.1029/2018JD028912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472638PMC
January 2019

Polyarticular Neurogenic Heterotopic Ossification in a Spinal Cord Injury: A Case Report from Saudi Arabia.

Cureus 2019 Feb 5;11(2):e4019. Epub 2019 Feb 5.

Physical Medicine and Rehabilitation, King Fahad Medical City, Riyadh, SAU.

A 33-year-old male victim of a motor vehicle accident, who presented with a T12 (thoracic 12 vertebra) burst fracture (ISNCSCI T11 AIS-A: International Standards for Neurological Classification of Spinal Cord Injury T11 ASIA Impairment Scale), was admitted to a rehabilitation hospital. A stage-II left ischial pressure ulcer was also reported. An X-ray of the pelvis revealed bilateral neurogenic heterotopic ossification (NHO) in both hips and knees, which was further confirmed by TC-99m methylene diphosphonate (MDP) bone scintigraphy. Read More

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http://dx.doi.org/10.7759/cureus.4019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453613PMC
February 2019

Occupational burnout and lifestyle in Kazakhstan cardiologists.

Arch Public Health 2019 10;77:13. Epub 2019 Apr 10.

1Al-Fabari Kazakh National University, al-Farabi avenue 71, Almaty, Kazakhstan 050040.

Background: No data exist in the published literature on burnout in physicians from Central Asia. The aim of this analysis was to assess burnout prevalence in doctors and nurses of a cardiological hospital in Almaty, Kazakhstan and ascertain whether smoking, alcohol and physical activity may predict job-associated burnout.

Methods: The staff of the City Cardiological Centre of Almaty ( = 259, 82% females) filled in the questionnaire with the questions on demographics, lifestyle, including smoking, alcohol and physical activity, as well as fatigue (using Fatigue Severity Scale (FSS)) and burnout using Maslach Burnout Inventory (MBI) Human Services Survey for Medical Personnel. Read More

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http://dx.doi.org/10.1186/s13690-019-0345-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457002PMC

Government pharmaceutical pricing strategies in the Asia-Pacific region: an overview.

J Mark Access Health Policy 2019 11;7(1):1601060. Epub 2019 Apr 11.

Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.

: Governments in Asia Pacific (APAC) are increasingly using pharmaceutical pricing strategies to contain rising healthcare costs. The objective of this narrative review is to discuss formal pricing strategies for reimbursed prescription medication in APAC, supported by relevant examples of implementation differences across countries. In the discussion section, we examine key advantages and disadvantages of each strategy. Read More

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http://dx.doi.org/10.1080/20016689.2019.1601060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461095PMC

Left atrial appendage closure device implantation guided with fluoroscopy only: Long-term results.

J Arrhythm 2019 Apr 4;35(2):262-266. Epub 2019 Feb 4.

Department of Cardiology and Vascular Medicine Faculty of Medicine Universitas Indonesia, and National Cardiovascular Center Harapan Kita Jakarta Indonesia.

Background: Left atrial appendage (LAA) closure device is an alternative to anticoagulants for stroke prevention in selected atrial fibrillation (AF) patients. The LAA device implantation is safe with short period of learning curve. The standard implantation technique warrants a transesophageal echocardiography (TEE) guided and general anesthesia. Read More

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http://dx.doi.org/10.1002/joa3.12151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457374PMC

Insulin use and fracture risk in patients with type 2 diabetes: A meta-analysis of 138,690 patients.

Exp Ther Med 2019 May 1;17(5):3957-3964. Epub 2019 Apr 1.

Department of Radiology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510627, P.R. China.

Patients with type 2 diabetes mellitus (T2DM) have been reported to have an enhanced risk of bone fracture, however the association between insulin treatment and risk of fracture in patients with T2DM remains to be fully elucidated. The aim of the present meta-analysis was to examine the possible association between insulin treatment and risk of fracture in patients with T2DM. Relevant studies published prior to and including April 2018 were identified by literature searches in PubMed, Embase and Cochrane Library databases. Read More

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http://dx.doi.org/10.3892/etm.2019.7461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468519PMC

Familial Creutzfeldt-Jakob Disease: The First Reported Kindred from South-East Asia.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):225-227

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Creutzfeldt-Jakob disease (CJD) belongs to a group of prion disease that is caused by abnormally folded proteins and is clinically characterized by rapidly progressive cognitive decline, gait abnormalities, and myoclonus. Familial CJD is very rare and is described only in few families around the world. We report a case with rapidly progressive cognitive decline, ataxia, and myoclonus, with a history of several members of his family developing similar symptoms and succumbing to it. Read More

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http://dx.doi.org/10.4103/aian.AIAN_441_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472217PMC

Have Synergies Between Nitrogen Deposition and Atmospheric CO Driven the Recent Enhancement of the Terrestrial Carbon Sink?

Global Biogeochem Cycles 2019 Feb 10;33(2):163-180. Epub 2019 Feb 10.

Institute for Climate and Atmospheric Science, School of Earth and Environment University of Leeds Leeds UK.

The terrestrial carbon sink has increased since the turn of this century at a time of increased fossil fuel burning, yet the mechanisms enhancing this sink are not fully understood. Here we assess the hypothesis that regional increases in nitrogen deposition since the early 2000s has alleviated nitrogen limitation and worked in tandem with enhanced CO fertilization to increase ecosystem productivity and carbon sequestration, providing a causal link between the parallel increases in emissions and the global land carbon sink. We use the Community Land Model (CLM4. Read More

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http://dx.doi.org/10.1029/2018GB005922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472506PMC
February 2019

Measuring Heterogeneity in Preferences over the Sex of Children.

Authors:
Johannes Norling

J Dev Econ 2018 Nov 5;135:199-221. Epub 2018 Jul 5.

Department of Economics, Mount Holyoke College.

This paper introduces a model-based approach for measuring heterogeneity in sex preferences using birth history records. The approach identifies the combinations of preferences over the sex and number of children that best explain observed childbearing. Empirical estimates indicate that a majority of parents in Africa, Asia, and the Americas consider the sex of children when making childbearing decisions. Read More

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http://dx.doi.org/10.1016/j.jdeveco.2018.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469715PMC
November 2018

Mantle Flow and Deforming Continents: From India-Asia Convergence to Pacific Subduction.

Tectonics 2018 Sep 6;37(9):2887-2914. Epub 2018 Sep 6.

C.R.P.G. Université de Lorraine Vandoeuvre-les-Nancy France.

The formation of mountain belts or rift zones is commonly attributed to interactions between plates along their boundaries, but the widely distributed deformation of Asia from Himalaya to the Japan Sea and other back-arc basins is difficult to reconcile with this notion. Through comparison of the tectonic and kinematic records of the last 50 Ma with seismic tomography and anisotropy models, we show that the closure of the former Tethys Ocean and the extensional deformation of East Asia can be best explained if the asthenospheric mantle transporting India northward, forming the Himalaya and the Tibetan Plateau, reaches East Asia where it overrides the westward flowing Pacific mantle and contributes to subduction dynamics, distributing extensional deformation over a 3,000-km wide region. This deep asthenospheric flow partly controls the compressional stresses transmitted through the continent-continent collision, driving crustal thickening below the Himalayas and Tibet and the propagation of strike-slip faults across Asian lithosphere further north and east, as well as with the lithospheric and crustal flow powered by slab retreat east of the collision zone below East and SE Asia. Read More

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http://dx.doi.org/10.1029/2018TC005036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472563PMC
September 2018

Spatial Variability of Groundwater Arsenic Concentration as Controlled by Hydrogeology: Conceptual Analysis Using 2-D Reactive Transport Modeling.

Water Resour Res 2018 Dec 26;54(12):10254-10269. Epub 2018 Dec 26.

Geological Survey of Denmark and Greenland Copenhagen Denmark.

Combined geological, hydrogeological, and geochemical controls on the arsenic concentration of contaminated aquifers in SE Asia were explored by two-dimensional (2-D) reactive transport modeling of data sets from Bangladesh, Cambodia, and Vietnam. For each site, the field data are summarized and used to create a conceptual 2-D reactive transport model that elucidates characteristic features influencing the groundwater arsenic concentration. Comparison of models for Bangladesh and Vietnam indicates that fine-grained layers overlying young sandy aquifers generate shallow high arsenic groundwater because low vertical groundwater velocities allow sufficient time for kinetic As release from the sediment. Read More

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http://dx.doi.org/10.1029/2018WR023685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472640PMC
December 2018

Bringing Development Back into Development Studies.

Authors:
Andrew M Fischer

Dev Change 2019 Mar 8;50(2):426-444. Epub 2019 Mar 8.

This article challenges Horner and Hulme's call to move from 'international development' to 'global development' with a reaffirmation of the classical traditions of development studies. With some adaptation to fit the changing contemporary context, these traditions not only remain relevant but also recover vital insights that have been obscured in the various fashionable re-imaginings of development. In particular, development thinking and agendas in the past were much more radical and ambitious in addressing the imperatives of redistribution and progressive forms of transformation in the context of stark asymmetries of wealth and power. Read More

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http://dx.doi.org/10.1111/dech.12490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472494PMC

Implementation of provider payment system reforms in the age of universal health coverage: a realist review of evidence from Asian developing countries.

J Health Serv Res Policy 2019 Apr 20:1355819619842305. Epub 2019 Apr 20.

3 Visiting Professor, Lee Kuan Yew School of Public Policy, National University of Singapore, Singapore.

Objective: Launched to assist in achieving universal health coverage, provider payment reform (PPR) is one of the most important policy tools deployed to transform incentives within a health system that is plagued with allocative inefficiency and high out-of-pocket payments to one that is able to deliver basic services and be cost-efficient. However, the black box of such reform - that is, the contexts in which reform operates, the mechanisms by which it changes health systems and behaviour within health systems, and the outcome patterns that arise from - remains unexplored. This review aims to examine the implementation mechanisms underlying PPR in Asian developing countries. Read More

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http://dx.doi.org/10.1177/1355819619842305DOI Listing

The Need to Develop a Strategy With an Evidence-Based Guideline for the Prevention of Gaming Disorder.

Asia Pac J Public Health 2019 Apr 21:1010539519844079. Epub 2019 Apr 21.

1 Shimane University, Izumo, Japan.

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http://dx.doi.org/10.1177/1010539519844079DOI Listing

Health Beliefs of Wearing Facemasks for Influenza A/H1N1 Prevention: A Qualitative Investigation of Hong Kong Older Adults.

Asia Pac J Public Health 2019 Apr 21:1010539519844082. Epub 2019 Apr 21.

6 Griffith University, Brisbane, Queensland, Australia.

Although vaccination is the first-line strategy controlling and preventing influenza A/H1N1 for older adults, personal protective measures, such as wearing facemasks, are also important preventive behaviors to reduce the risk of becoming infected with influenza A/H1N1 during a pandemic. In the current study, we aimed to explore the belief-related psychological factors of wearing facemasks for influenza A/H1N1 prevention in a sample of Hong Kong older adults. Community-dwelling Chinese adults (N = 137) aged between 65 and 80 years (M = 75. Read More

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http://dx.doi.org/10.1177/1010539519844082DOI Listing
April 2019
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Systemic hemodynamic atherothrombotic syndrome (SHATS): Diagnosis and severity assessment score.

Authors:
Kazuomi Kario

J Clin Hypertens (Greenwich) 2019 Apr 22. Epub 2019 Apr 22.

Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan.

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http://dx.doi.org/10.1111/jch.13542DOI Listing

Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial among Pregnant Women of Rural Bangladesh.

J Nutr 2019 Apr 22. Epub 2019 Apr 22.

Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

Background: Antenatal multiple micronutrient (MM) supplementation improves birth outcomes relative to iron-folic acid (IFA) in developing countries, but limited data exist on its impact on pregnancy micronutrient status.

Objective: We assessed the efficacy of a daily MM (15 nutrients) compared with IFA supplement, each providing approximately 1 RDA of nutrients and given beginning at pregnancy ascertainment, on late pregnancy micronutrient status of women in rural Bangladesh. Secondarily, we explored other contributors to pregnancy micronutrient status. Read More

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http://dx.doi.org/10.1093/jn/nxz046DOI Listing

Cardiovascular Risk Assessment Chart by Dietary Factors in Japan - NIPPON DATA80.

Circ J 2019 Apr 19. Epub 2019 Apr 19.

Department of Public Health, Shiga University of Medical Science.

Background: Many studies show that dietary factors such as vegetables, fruit, and salt are associated with cardiovascular disease (CVD) risk. However, a risk assessment chart for CVD mortality according to combinations of dietary factors has not been established.Methods and Results:Participants were 9,115 men and women aged 30-79 years enrolled in the National Nutritional Survey of Japan in 1980 with a 29-year follow-up. Read More

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http://dx.doi.org/10.1253/circj.CJ-18-1002DOI Listing

The culture, mental health and psychosocial wellbeing of Rohingya refugees: a systematic review.

Epidemiol Psychiatr Sci 2019 Apr 22:1-6. Epub 2019 Apr 22.

Public Health Section, United Nations High Commissioner for Refugees,Geneva,Switzerland.

AimsDespite the magnitude and protracted nature of the Rohingya refugee situation, there is limited information on the culture, mental health and psychosocial wellbeing of this group. This paper, drawing on a report commissioned by the United Nations High Commissioner for Refugees (UNHCR), aims to provide a comprehensive synthesis of the literature on mental health and psychosocial wellbeing of Rohingya refugees, including an examination of associated cultural factors. The ultimate objective is to assist humanitarian actors and agencies in providing culturally relevant Mental Health and Psychosocial Support (MHPSS) for Rohingya refugees displaced to Bangladesh and other neighbouring countries. Read More

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http://dx.doi.org/10.1017/S2045796019000192DOI Listing
April 2019
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Nipah virus: epidemiology, pathology, immunobiology and advances in diagnosis, vaccine designing and control strategies - a comprehensive review.

Vet Q 2019 Dec;39(1):26-55

k National Institute of Virology , Ministry of Health and Family Welfare, Govt of India , Pune , India.

Nipah (Nee-pa) viral disease is a zoonotic infection caused by Nipah virus (NiV), a paramyxovirus belonging to the genus Henipavirus of the family Paramyxoviridae. It is a biosafety level-4 pathogen, which is transmitted by specific types of fruit bats, mainly Pteropus spp. which are natural reservoir host. Read More

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December 2019

Comparative evaluation of novel screening strategies for colorectal cancer screening in China (TARGET-C): a study protocol for a multicentre randomised controlled trial.

BMJ Open 2019 Apr 20;9(4):e025935. Epub 2019 Apr 20.

Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Introduction: Screening for colorectal cancer (CRC) is effective in reducing the disease burden. However, high-level evidence from randomised controlled trials on the effectiveness of CRC screening modalities is still lacking. We will conduct a large-scale multicentre randomised controlled trial in China to evaluate the effectiveness and cost-effectiveness of different CRC screening strategies. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025935DOI Listing

Serogroup-specific meningococcal carriage by age group: a systematic review and meta-analysis.

BMJ Open 2019 Apr 20;9(4):e024343. Epub 2019 Apr 20.

Sanofi Pasteur, Inc., Swiftwater, Pennsylvania, USA.

Objective: carriage prevalence has known variation across the lifespan, but it is unclear whether carriage varies among meningococcal capsular groups. Therefore, we aimed to characterise group-specific meningococcal carriage by age group and world region from 2007 to 2016.

Design: Systematic review and meta-analysis. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024343DOI Listing

Patterns of outdoor exposure to heat in three South Asian cities.

Sci Total Environ 2019 Apr 9;674:264-278. Epub 2019 Apr 9.

Wageningen University and Research, Wageningen Environmental Research, Wageningen, the Netherlands; London School of Economics and Political Science, Grantham Research Institute, London, United Kingdom.

Low socio-economic status has been widely recognized as a significant factor in enhancing a person's vulnerability to climate change including vulnerability to changes in temperature. Yet, little is known about exposure to heat within cities in developing countries, and even less about exposure within informal neighbourhoods in those countries. This paper presents an assessment of exposure to outdoor heat in the South Asian cities Delhi, Dhaka, and Faisalabad. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697193160
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http://dx.doi.org/10.1016/j.scitotenv.2019.04.087DOI Listing
April 2019
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Spatial-temporal variations and source contributions to forest ozone exposure in China.

Sci Total Environ 2019 Apr 9;674:189-199. Epub 2019 Apr 9.

Zachry Department of Civil Engineering, Texas A&M University, College Station, TX 77843, USA. Electronic address:

As surface ozone (O) concentrations have significantly increased in many regions of China, it is concerned that O may cause negative impacts on forests in the country. To estimate the risks of O exposure to forest health, several frequently used O exposure indices (M7, M24, N100, SUM60, W126, and AOT40f) were calculated for the entire year of 2013 and the source contributions to exposure in April and August were quantified using a source-oriented version of the Community Multiscale Air Quality (CMAQ) model. Critical loads for natural ecosystems (12 ppm-h for SUM60) and for moderately sensitive plant species (23. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.04.106DOI Listing
April 2019
2 Reads

Five-year observation of aerosol optical properties and its radiative effects to planetary boundary layer during air pollution episodes in North China: Intercomparison of a plain site and a mountainous site in Beijing.

Sci Total Environ 2019 Mar 31;674:140-158. Epub 2019 Mar 31.

State Key Laboratory of Severe Weather (LASW) and Institute of Atmospheric Composition, Chinese Academy of Meteorological Sciences, CMA, Beijing 100081, China.

The aerosol microphysical, optical and radiative properties of the whole column and upper planetary boundary layer (PBL) were investigated during 2013 to 2018 based on long-term sun-photometer observations at a surface site (~106 m a.s.l. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.03.418DOI Listing

Modificated Mahuang-Tang, a traditional herbal medicine suppresses inflammatory responses induced by cigarette smoke in human airway epithelial cell and mice.

Phytomedicine 2018 Dec 1;59:152777. Epub 2018 Dec 1.

College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757, Republic of Korea. Electronic address:

Background: Cigarette smoke (CS) is a major contributor to the high incidence of chronic obstructive pulmonary disease (COPD) featured as chronic inflammation and airway obstruction. Mahuang-Tang is a traditional polyherbal mixture composed of four different herbs. It is widely used in Asia as a remedy for allergic reaction and inflammation. Read More

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http://dx.doi.org/10.1016/j.phymed.2018.11.037DOI Listing
December 2018

Cytotoxic polyphenolic compounds from Lespedeza bicolor stem bark.

Fitoterapia 2019 Apr 17. Epub 2019 Apr 17.

G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, Vladivostok, 690022, Russia.

Four new pterocarpans (6aR,11aR)-6a,11a-dihydrolespedezol A (2), (6aR,11aR)-2-isoprenyl-6a,11a-dihydrolespedezol A (3), (6aR,11aR,3'R)-6a,11a-dihydrolespedezol A (4), (6aR,11aR,3'S)-6a,11a-dihydrolespedezol A (5) and one new stilbenoid with 1,2-diketone fragment named bicoloketone (6) along with one previously known pterocarpen lespedezol A (1) have been isolated from Lespedeza bicolor stem bark using multistage column chromatography on polyamide and silica gel. The structures of the isolated polyphenolic compounds were determined by spectroscopic methods. The absolute configurations of 4 and 5 were determined by comparison of their electronic circular dichroism (ECD) spectra obtained experimentally and the spectra calculated using time-dependent density functional theory (TDDFT). Read More

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http://dx.doi.org/10.1016/j.fitote.2019.04.003DOI Listing
April 2019
2 Reads

Carrier frequency of spinal muscular atrophy in Thailand.

Neurol Sci 2019 Apr 19. Epub 2019 Apr 19.

Department of Internal Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Spinal muscular atrophy (SMA) is one of the leading causes of death in infants and young children from heritable diseases. Patients diagnosed with SMA develop symmetrical progressive muscle weakness and atrophy from degeneration of alpha motor neurons. Approximately 95% of patients have a homozygous deletion of survival motor neuron 1 (SMN1) gene in exon 7 and inherited in autosomal recessive pattern. Read More

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http://link.springer.com/10.1007/s10072-019-03885-5
Publisher Site
http://dx.doi.org/10.1007/s10072-019-03885-5DOI Listing
April 2019
1 Read

International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.

EBioMedicine 2019 Apr 16. Epub 2019 Apr 16.

Parasites and microbes, Wellcome Sanger Institute, Hinxton, UK.

Background: Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiotic resistance and invasiveness, in the context of genetic background.

Methods: Our dataset of 13,454 genomes, combined with four published genomic datasets, represented Africa (40%), Asia (25%), Europe (19%), North America (12%), and South America (5%). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23523964193025
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http://dx.doi.org/10.1016/j.ebiom.2019.04.021DOI Listing
April 2019
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The impact of sex on risk of cardiovascular disease and all-cause mortality in adults with or without diabetes mellitus: A comparison between the U.S. and Japan.

J Diabetes Complications 2019 Apr 1. Epub 2019 Apr 1.

Department of Public Health, Shiga University of Medical Science, Otsu, Shiga, Japan; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Shiga, Japan.

Aims: To test a hypothesis that women with diabetes mellitus (DM) versus those without DM had a significantly higher risk of heart disease (HD), stroke and all-cause mortality than their male counterparts in the U.S. as well as in Japan. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10568727183131
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http://dx.doi.org/10.1016/j.jdiacomp.2019.03.008DOI Listing
April 2019
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Longitudinal magnetic resonance imaging changes in Japanese encephalitis.

Brain Dev 2019 Apr 16. Epub 2019 Apr 16.

Department of Pediatrics, Asahi General Hospital, Chiba, Japan.

Background: Japanese encephalitis is a flavivirus that can cause pandemic encephalitis, and is prevalent in Southeast Asia and Australia. Brain images of patients with Japanese encephalitis are characterized by thalamic lesions, distinct from those seen in viral encephalopathies caused by the herpes simplex virus and West Nile virus.

Aim: Herein, we describe for the first time a time-dependent magnetic resonance imaging pattern in Japanese encephalitis in a 10-month-old Japanese boy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03877604183056
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http://dx.doi.org/10.1016/j.braindev.2019.04.005DOI Listing
April 2019
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Coastal ecosystem in East Asia: Pollution and management.

Environ Pollut 2019 Apr 6. Epub 2019 Apr 6.

Chinese Academy of Sciences, China.

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https://linkinghub.elsevier.com/retrieve/pii/S02697491193174
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http://dx.doi.org/10.1016/j.envpol.2019.04.015DOI Listing
April 2019
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Computerized intervention to prevent drug use among at-risk adolescents in Central Asia: Preliminary family-level findings from a pilot mixed methods trial.

Int J Drug Policy 2019 Apr 16;68:75-85. Epub 2019 Apr 16.

Global Health Research Center of Central Asia (GHRCCA), Almaty, Kazakhstan.

Background: The rapidly growing rates of HIV infection in Kazakhstan are largely driven by injection drug use. The study adapts a family-focused evidence-based HIV and substance use prevention intervention for at-risk adolescents from communities in Almaty that have been greatly affected by heroin trade and use.

Methods: This NIDA-funded pilot feasibility trial included 181 at-risk adolescents (ages 14-17) recruited through local schools and 181 of their parents or other adult family members. Read More

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http://dx.doi.org/10.1016/j.drugpo.2019.03.022DOI Listing

Psychological Distress among Adolescents in Laos, Mongolia, Nepal, and Sri Lanka.

Asian Nurs Res (Korean Soc Nurs Sci) 2019 Apr 16. Epub 2019 Apr 16.

Hanyang University, College of Medicine, Department of Preventive Medicine; Hanyang University, Institute for Health and Society, Seoul, Republic of Korea.

Purpose: The purpose of this study was to explore psychological distress and examine the relationship between this distress and individual, family, and school factors among adolescents in four low- and middle-income countries (LAMICs) in Asia (i.e., Laos, Mongolia, Nepal, and Sri Lanka). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19761317183023
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http://dx.doi.org/10.1016/j.anr.2019.04.001DOI Listing
April 2019
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Association between excessive supraventricular ectopy and subclinical cerebrovascular disease: A population-based study.

Eur J Neurol 2019 Apr 19. Epub 2019 Apr 19.

Department of Public Health, Shiga University of Medical Science, Otsu, Japan.

Background: The association between an increased supraventricular ectopic beat (SVEB) and subclinical cerebrovascular disease remains unclear. Given the emerging concept that an increased SVEB is a marker of atrial cardiomyopathy or atherosclerosis burden, we sought to determine whether excessive supraventricular ectopic activity (ESVEA) is associated with a higher burden of subclinical cerebrovascular disease in the middle-aged to older cohort with neither apparent stroke nor atrial fibrillation.

Methods: We conducted a cross-sectional population-based study of 462 men (mean age, 68. Read More

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http://dx.doi.org/10.1111/ene.13970DOI Listing

Association of Diabetes With All-Cause and Cause-Specific Mortality in Asia: A Pooled Analysis of More Than 1 Million Participants.

JAMA Netw Open 2019 Apr 5;2(4):e192696. Epub 2019 Apr 5.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

Importance: Asia is home to the largest diabetic populations in the world. However, limited studies have quantified the association of diabetes with all-cause and cause-specific mortality in Asian populations.

Objectives: To evaluate the association of diabetes with all-cause and cause-specific mortality in Asia and to investigate potential effect modifications of the diabetes-mortality associations by participants' age, sex, education level, body mass index, and smoking status. Read More

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2019.2696DOI Listing
April 2019
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Outcomes of Bedaquiline Treatment in Patients with Multidrug-Resistant Tuberculosis.

Emerg Infect Dis 2019 May;25(5):936-943

Bedaquiline is recommended by the World Health Organization for the treatment of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). We pooled data from 5 cohorts of patients treated with bedaquiline in France, Georgia, Armenia, and South Africa and in a multicountry study. The rate of culture conversion to negative at 6 months (by the end of 6 months of treatment) was 78% (95% CI 73. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1823_article.htm
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http://dx.doi.org/10.3201/eid2505.181823DOI Listing
May 2019
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Severe Myasthenic Manifestation of Leptospirosis Associated with New Sequence Type of Leptospira interrogans.

Emerg Infect Dis 2019 May;25(5):968-971

We report the rapid development of a myasthenic crisis as the first-time manifestation of myasthenia gravis. The symptoms developed in the course of acute leptospirosis associated with a new sequence type of Leptospira interrogans. Antibiotic treatment led to rapid amelioration of myasthenia. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1591_article.htm
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http://dx.doi.org/10.3201/eid2505.181591DOI Listing
May 2019
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Southeast Asia Strategic Multilateral Dialogue on Biosecurity.

Emerg Infect Dis 2019 May;25(5)

A strategic multilateral dialogue related to biosecurity risks in Southeast Asia, established in 2014, now includes participants from Singapore, Malaysia, Indonesia, Thailand, Philippines, and the United States. This dialogue is conducted at the nonministerial level, enabling participants to engage without the constraints of operating in their official capacities. Participants reflect on mechanisms to detect, mitigate, and respond to biosecurity risks and highlight biosecurity issues for national leadership. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1659_article.htm
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http://dx.doi.org/10.3201/eid2505.181659DOI Listing
May 2019
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Pre-diagnostic blood levels of organochlorines and risk of non-Hodgkin lymphoma in three prospective cohorts in China and Singapore.

Int J Cancer 2019 Apr 19. Epub 2019 Apr 19.

Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Rockville, MD, USA.

Specific organochlorines (OCs) have been associated with non-Hodgkin lymphoma (NHL) with varying degrees of evidence. These associations have not been evaluated in Asia, where the high exposure and historical environmental contamination of certain OC pesticides (e.g. Read More

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http://dx.doi.org/10.1002/ijc.32350DOI Listing

Urine salts elucidate Early Neolithic animal management at Aşıklı Höyük, Turkey.

Sci Adv 2019 Apr 17;5(4):eaaw0038. Epub 2019 Apr 17.

Department of Prehistory, Istanbul University, Istanbul 34134, Turkey.

The process of sheep and goat (caprine) domestication began by 9000 to 8000 BCE in Southwest Asia. The early Neolithic site at Aşıklı Höyük in central Turkey preserves early archaeological evidence of this transformation, such as culling by age and sex and use of enclosures inside the settlement. People's strategies for managing caprines evolved at this site over a period of 1000 years, but changes in the scale of the practices are difficult to measure. Read More

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http://advances.sciencemag.org/lookup/doi/10.1126/sciadv.aaw
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http://dx.doi.org/10.1126/sciadv.aaw0038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469938PMC
April 2019
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Two New Species of the Genus from China and Korea.

Mycobiology 2019 Mar 23;47(1):40-49. Epub 2019 Mar 23.

Korean Lichen Research Institute (KoLRI), Sunchon National University, Suncheon, Korea.

is a widespread lineage of lichenized ascomycetes with ambiguous relationships among species that have not solved completely. In this study, several specimens belonging to were collected from China and South Korea, and the internal transcribed spacer region was generated to confirm the system position of the newly collected specimens. Combined with a morphological examination and phylogenetic analysis, two new areolate species, and , are new to science. Read More

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https://www.tandfonline.com/doi/full/10.1080/12298093.2019.1
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http://dx.doi.org/10.1080/12298093.2019.1583785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452912PMC
March 2019
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