875,313 results match your criteria Asia Pacific Education Review[Journal]


Association between central sleep apnea and atrial fibrillation/flutter in Japanese-American men: The Kuakini Honolulu Heart Program (HHP) and Honolulu-Asia Aging Study (HAAS).

J Electrocardiol 2020 May 12;61:10-17. Epub 2020 May 12.

University of Hawai'i at Mānoa, Department of Geriatric Medicine, John A. Burns School of Medicine, 347 N Kuakini St, Honolulu, HI, USA; Kuakini Medical Center, 347 N Kuakini St, Honolulu, HI, USA. Electronic address:

Introduction: While several studies have indicated that central sleep apnea (CSA) is associated with atrial fibrillation and atrial flutter (AF) in older populations, few studies have focused on older Asian populations.

Methods: We conducted a cross- sectional analysis using data from the 1999-2000, 7th exam cycle of the Kuakini Honolulu-Asia Aging Study. Participants were 718 Japanese-American men between 79 and 97 years old, who had overnight polysomnography. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2020.05.005DOI Listing

Documenting the heritage along the Silk Road: An ethnobotanical study of medicinal teas used in Southern Xinjiang, China.

J Ethnopharmacol 2020 May 25:113012. Epub 2020 May 25.

Department of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China; Southeast Asia Biodiversity Research Institute, Chinese Academy of Sciences, Menglun, Mengla, Yunnan, 666303, China. Electronic address:

Ethnopharmacological Relevance: People in Southern Xinjiang, China have been consuming medicinal teas for healthcare since before the ancient Silk Road markets began. Several pharmaceutical studies have illustrated the potential healthcare benefits of medicinal teas used in Southern Xinjiang, China. However, little information is available from the literature about the diversity of the species used and related traditional knowledge of these medicinal teas. Read More

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http://dx.doi.org/10.1016/j.jep.2020.113012DOI Listing

Effects of Substrates on the Production of Fruiting Bodies and the Bioactive Components by Different Cordyceps militaris Strains (Ascomycetes).

Int J Med Mushrooms 2020 ;22(1):55-63

College of Animal Science and Technology, Jilin Agricultural University, Xincheng Str. 2888, 130118, Changchun, China.

Cordyceps militaris is a type of food and medicinal species and is widely cultured in Asia. Substrate and strain are important factors for the production of fruiting bodies and bioactive components contents in fruiting bodies of C. militaris. Read More

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http://dx.doi.org/10.1615/IntJMedMushrooms.2019033257DOI Listing
January 2020

Fruiting Bodies of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes) Alleviate Diabetes-Associated Oxidative Stress.

Int J Med Mushrooms 2020 ;22(1):15-29

Department of Natural Sciences, Fu Jen Catholic University, #510, JhongZheng Rd., Xinzhuang District, New Taipei City, 24205, Taiwan, ROC.

Hyperglycemia-induced complications, the major causes of death in diabetes, are closely related to the elevated oxidative stress. Our previous study indicated that fruiting bodies of Ophiocordyceps sinensis attenuated polydipsia and hyperglycemia in diabetic rats. In this study, we further investigated whether the protective effects of O. Read More

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http://dx.doi.org/10.1615/IntJMedMushrooms.2019033275DOI Listing
January 2020

Positioning and utilization of information and communication technology (ICT) in community pharmacies: a cross sectional study from Selangor, Malaysia.

JMIR Med Inform 2020 May 13. Epub 2020 May 13.

Unaizah College of Pharmacy, Qassim University, Unaizah, SA.

Background: Information and communication technology (ICT) is an essential element of modern "smart" cities. These smart cities have integrated housing, marketplace, public amenities, services, business and transportation linked via the ICT. ICT is also used widely in urban healthcare delivery. Read More

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http://dx.doi.org/10.2196/17982DOI Listing

Management of Heart Failure Patients with COVID-19. A Joint Position Paper of the Chinese Heart Failure Association & National Heart Failure Committee and the Heart Failure Association of the European Society of Cardiology.

Eur J Heart Fail 2020 May 28. Epub 2020 May 28.

Cardiology, ASST Spedali Civili di Brescia and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.

The Coronavirus Disease 2019 (COVID-19) pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is causing considerable morbidity and mortality worldwide. Multiple reports have suggested that patients with heart failure (HF) are at a higher risk of severe disease and mortality with COVID-19. Moreover, evaluating and treating HF patients with comorbid COVID-19 represents a formidable clinical challenge as symptoms of both conditions may overlap and they may potentiate each other. Read More

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http://dx.doi.org/10.1002/ejhf.1915DOI Listing

Mediating Effect of Internet Addiction on the Relationship Between Individualism and Cyberbullying: Cross-Sectional Questionnaire Study.

J Med Internet Res 2020 May 28;22(5):e16210. Epub 2020 May 28.

College of Engineering and Technology, American University of the Middle East, Kuwait.

Background: Among a variety of dynamics that may have effects on internet-related behaviors, cultural orientation is particularly important. Previous studies suggest that individualism is a strong determinant of certain behaviors. In addition, findings suggest that vertical individualism may lead to the development of more tolerance for addiction and aggression on the internet. Read More

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http://dx.doi.org/10.2196/16210DOI Listing

PYGB Promoted Tumor Progression by Regulating Wnt/β-Catenin Pathway in Gastric Cancer.

Technol Cancer Res Treat 2020 Jan-Dec;19:1533033820926592

Department of Gastrointestinal Anorectal Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing City, China.

Gastric cancer is one of the most common gastrointestinal malignancy with high mortality in East Asia. Investigation of pathogenic mechanisms of gastric cancer is crucial to develop novel therapeutic strategies and identify new therapeutic candidates. Brain-type glycogen phosphorylase is a glycogen phosphorylase involved in glycogen metabolism, which participates in multiple physiological and pathological processes. Read More

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http://dx.doi.org/10.1177/1533033820926592DOI Listing

Another outlook to sector-level energy consumption in Pakistan from dominant energy sources and correlation with economic growth.

Environ Sci Pollut Res Int 2020 May 28. Epub 2020 May 28.

Beijing Key Laboratory of New Energy and Low Carbon Development, School of Economics and Management, North China Electric Power University, Beijing, 102206, China.

The present study seeks to investigate the sector-level energy consumption of oil and natural gas and to explore the linkage between economic growth, households, agriculture, industry, power, fertilizers, and commercial sector in Pakistan for the period of 1980-2016. The energy sector of Pakistan is facing severe crisis from the last few years due to inadequate production and supply. Long-lasting deficits of natural gas and oil, the two supreme types of fuel in Pakistan, had detrimental consequences for the growth as well as for the economic development. Read More

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http://dx.doi.org/10.1007/s11356-020-09245-7DOI Listing

Education background and monthly household income are factors affecting the knowledge, awareness and practice on haze pollution among Malaysians.

Environ Sci Pollut Res Int 2020 May 27. Epub 2020 May 27.

School of Medicine, Faculty of Health and Medical Sciences, Taylor's University, No. 1, Jalan Taylor's, 47500, Subang Jaya, Selangor, Malaysia.

Transboundary haze pollution caused by periodic forest fires has initiated a serious negative implication to the economy, tourism sectors and public health in Southeast Asia. Due to the raising concerns of health effects of haze towards the Malaysian population, the present study was conducted to investigate the degree of awareness towards haze and the number of safety measures adopted by the Malaysian population during the haze crisis based on demographic characteristics. A cross-sectional questionnaire-based study was conducted from 4 to 29 January 2016 on 387 subjects in Klang Valley, Malaysia. Read More

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http://dx.doi.org/10.1007/s11356-020-09196-zDOI Listing

Sexual dysfunction in polycystic ovary syndrome: a systematic review and meta-analysis.

Hormones (Athens) 2020 May 27. Epub 2020 May 27.

Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

Purpose: Polycystic ovarian syndrome (PCOS) is a common disorder characterized by clinical or biochemical hyperandrogenism and ovulary dysfunction. Female sexual dysfunction (FSD) adversely affects quality of life and interpersonal relationships. We aimed to compare the prevalence of FSD in women with and without PCOS. Read More

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http://dx.doi.org/10.1007/s42000-020-00210-0DOI Listing

Is Korea Ready to Be a Key Player in the Medical Tourism Industry? An English Education Perspective.

Iran J Public Health 2020 Feb;49(2):267-273

Asia Contents Institute, Konkuk University, Seoul, South Korea.

Background: This study attempted to identify the problem South Korea faces in its development of the medical tourism industry from the perspective of English education.

Methods: To assess the preparedness and problems of future Korean nurses in dealing with foreign patients, a questionnaire was conducted in 2017 on 146 freshman and sophomore nursing major students at CHA University in South Korea.

Results: Although the nursing major students were highly satisfied with the English instructors, they did not feel that the curriculum prepared them well to deal with foreign patients in the future. Read More

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February 2020

Unusual presentation of melioidosis in a returning traveler.

IDCases 2020 12;20:e00809. Epub 2020 May 12.

Division of Infectious Diseases, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Melioidosis is endemic in Southeast Asia and Australia and cases outside those regions are often travel related. We present a case of melioidosis in a man, with no known risk factors who had an unusual presentation with an infected abdominal aortic aneurysm by in Saudi Arabia, a country with no previous reported cases of this infection. It occurred after traveling to Thailand and he was treated successfully with medical therapy and surgical intervention. Read More

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http://dx.doi.org/10.1016/j.idcr.2020.e00809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240328PMC

Crimean-Congo Hemorrhagic Fever Virus: Advances in Vaccine Development.

Biores Open Access 2020 12;9(1):137-150. Epub 2020 May 12.

Division of Virology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.

Crimean-Congo hemorrhagic fever (CCHF) is a severe human disease with mortality rates of up to 30%. The disease is widespread in Africa, Asia, the Middle East and Eastern Europe. The last few years have seen disease emergence in Spain for the first time and disease re-emergence in other regions of the world after periods of inactivity. Read More

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http://dx.doi.org/10.1089/biores.2019.0057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247048PMC

COVID-19 Pandemic: Marked Global Disparities in Fatalities According to Geographic Location and Universal Health Care.

Int J MCH AIDS 2020 15;9(2):213-216. Epub 2020 May 15.

Center of Excellence in Health Equity, Training, and Research, Baylor College of Medicine, Houston, TX, USA.

Since its outbreak, COVID-19 pandemic has been the biggest global concern with exponentially increasing number of cases and associated deaths across all habitable continents. Various countries around the world with their diverse health care systems, have responded to the pandemic in very distinctive ways. In this paper, we: compared COVID-19 mortality rates across global geographic regions; and assessed differences in COVID-19-related case fatality rate (CFR) based on presence or absence of Universal Health Coverage (UHC). Read More

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http://dx.doi.org/10.21106/ijma.389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248683PMC

Multicenter dataset of multi-shell diffusion MRI in healthy traveling adults with identical settings.

Sci Data 2020 May 27;7(1):157. Epub 2020 May 27.

Center for Brain Imaging Science and Technology, Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrumental Science, Zhejiang University, Hangzhou, Zhejiang, China.

Multicenter diffusion magnetic resonance imaging (MRI) has drawn great attention recently due to the expanding need for large-scale brain imaging studies, whereas the variability in MRI scanners and data acquisition tends to confound reliable individual-based analysis of diffusion measures. In addition, a growing number of multi-shell diffusion models have been shown with the potential to generate various estimates of physio-pathological information, yet their reliability and reproducibility in multicenter studies remain to be assessed. In this article, we describe a multi-shell diffusion dataset collected from three traveling subjects with identical acquisition settings in ten imaging centers. Read More

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http://dx.doi.org/10.1038/s41597-020-0493-8DOI Listing

Penetrating ocular trauma by nail of a badminton feather shuttle cock: A rare case report.

Indian J Ophthalmol 2020 Jun;68(6):1209-1211

Department of Vitreo Retina, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.

Sports-related ocular traumas may be rare, but can have devastating and disabling consequences. The causes of eye-related injuries depend on the type of sports popular in a particular area or country. Badminton is a popular sport played by all age groups and socioeconomic segments and is popular in many parts of the world. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1681_19DOI Listing

International Association of Contact Lens Educators: Exceptional education-Exponential impact.

Indian J Ophthalmol 2020 Jun;68(6):984-987

International Association of Contact Lens Educators, Bengaluru, Karnataka, India.

The International Association of Contact Lens Educators (IACLE) is the leading provider of educational and information resources essential to contact lens educators worldwide. The New IACLE Contact Lens Course is its most important resource, used by members around the world to teach their students, the contact lens practitioners of the future. In 2019, IACLE celebrated the 40th Anniversary of its founding meeting. Read More

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http://dx.doi.org/10.4103/ijo.IJO_2065_19DOI Listing

Long-read bitter gourd () genome and the genomic architecture of nonclassic domestication.

Proc Natl Acad Sci U S A 2020 May 27. Epub 2020 May 27.

Institute of Ecology and Evolutionary Biology, National Taiwan University, Taipei 10617, Taiwan;

The genetic architecture of quantitative traits is determined by both Mendelian and polygenic factors, yet classic examples of plant domestication focused on selective sweep of newly mutated Mendelian genes. Here we report the chromosome-level genome assembly and the genomic investigation of a nonclassic domestication example, bitter gourd (), an important Asian vegetable and medicinal plant of the family Cucurbitaceae. Population resequencing revealed the divergence between wild and South Asian cultivars about 6,000 y ago, followed by the separation of the Southeast Asian cultivars about 800 y ago, with the latter exhibiting more extreme trait divergence from wild progenitors and stronger signs of selection on fruit traits. Read More

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http://dx.doi.org/10.1073/pnas.1921016117DOI Listing

Detection of multiple hypervirulent Klebsiella pneumoniae strains in a New York City hospital through screening of virulence genes.

Clin Microbiol Infect 2020 May 24. Epub 2020 May 24.

Columbia University Irving Medical Center, Department of Pathology & Cell Biology, 630 West 168th Street, New York, NY 10032, USA.

Objectives: The 'hypervirulent' variant of Klebsiella pneumoniae (hvKp) is a predominant cause of community-acquired pyogenic liver abscess in Asia, and is an emerging pathogen in Western countries. hvKp infections have demonstrated 'metastatic' dissemination in immunocompetent hosts, an unusual mode of infection associated with severe complications. Two cases alerted us to the possible presence of hvKp at our hospital, both involving elderly Hispanic males who presented with recurrent fever, bacteremia, epigastric pain, and liver abscesses/phlegmon, thus prompting an assessment of hvKp prevalence. Read More

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http://dx.doi.org/10.1016/j.cmi.2020.05.012DOI Listing

The value of extensive catheter linear ablation on persistent atrial fibrillation (the CLEAR-AF Study).

Int J Cardiol 2020 May 24. Epub 2020 May 24.

Cardiac Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: The ablation therapy for persistent atrial fibrillation (PerAF) is still a challenge due to the high recurrence rate. This study was aimed to investigate the value of extensive linear ablation with contact force sensing techniques for PerAF.

Methods: A total of 214 patients with PerAF were enrolled in five centers. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.05.032DOI Listing

Multidisciplinary approach to assess the toxicities of arsenic and barium in drinking water.

Environ Health Prev Med 2020 May 27;25(1):16. Epub 2020 May 27.

Departments of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.

Well water could be a stable source of drinking water. Recently, the use of well water as drinking water has been encouraged in developing countries. However, many kinds of disorders caused by toxic elements in well drinking water have been reported. Read More

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http://dx.doi.org/10.1186/s12199-020-00855-8DOI Listing

Vernakalant hydrochloride for the treatment of atrial fibrillation: evaluation of its place in clinical practice.

Future Cardiol 2020 May 28. Epub 2020 May 28.

Liverpool Centre for Cardiovascular Science, University of Liverpool & Liverpool Heart & Chest Hospital, Liverpool, L7 8TX, UK.

Vernakalant is an intravenous anti-arrhythmic drug available in Europe, Canada and some countries in Asia for the restoration of sinus rhythm in acute onset atrial fibrillation. Currently, it is not available in USA because the US FDA have ongoing concerns about its safety. Vernakalant has a unique pharmacological profile of multi-ion channel activity and atrial-specificity that distinguishes it from other anti-arrhythmic drugs. Read More

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http://dx.doi.org/10.2217/fca-2020-0039DOI Listing

Changes in Emberiza bunting communities and populations spanning 100 years in Korea.

PLoS One 2020 27;15(5):e0233121. Epub 2020 May 27.

Korea National Park Service, Wonju, Gangwon Province, South Korea.

The rapid decline of a few Emberiza bunting species is increasing conservation concerns, especially in Asia. However, temporal changes in communities and populations of buntings, ones of the most common migratory songbirds in Korea, have not been quantitatively assessed. To understand how the status of buntings has changed over the past 100 years, we collated abundance data from museum collections and bird-banding records between 1910 and 2019. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233121PLOS

Current cannabis-related situation in the Asia-Pacific region.

Curr Opin Psychiatry 2020 Jul;33(4):352-359

Drug Dependence Research Center, WHO Collaborating Centre for Research and Training in Drug Dependence, Health and Social Science and Addiction Research Unit, College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand.

Purpose Of Review: We present information on cannabis policy, demand, and supply in the Asia-Pacific region.

Method: A systematic review of peer-reviewed articles using PubMed, MEDLINE, and reliable sources was conducted. We classified the policy implemented in each country into conducting research, legalization of medical and recreational use, decriminalization, cultivation, and others. Read More

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http://dx.doi.org/10.1097/YCO.0000000000000616DOI Listing

Advances and Latest Developments in Ophthalmology and Visual Sciences.

Authors:
Jost B Jonas

Asia Pac J Ophthalmol (Phila) 2020 May 26. Epub 2020 May 26.

Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Germany.

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http://dx.doi.org/10.1097/APO.0000000000000298DOI Listing

High Myopia and Glaucoma-Like Optic Neuropathy.

Asia Pac J Ophthalmol (Phila) 2020 May 26. Epub 2020 May 26.

Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karis-University, Mannheim, Germany.

Purpose: Previous population-based and hospital-based studies have shown an association between high myopia and higher prevalence of glaucomatous or glaucoma-like optic neuropathy (GON). Here we discuss potential factors associated with such a correlation.

Design: Review. Read More

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http://dx.doi.org/10.1097/APO.0000000000000288DOI Listing

Arterial Occlusions to the Eye: From Retinal Emboli to Ocular Ischemic Syndrome.

Asia Pac J Ophthalmol (Phila) 2020 May 26. Epub 2020 May 26.

Department of Neurology, Flinders University and the Calvary Adelaide Hospital, Adelaide, Australia.

: Abstract: A loss or lack of blood supply to the eye can result in acute loss of vision. The site of ischemia may be at the level of the retinal arterioles, the central retinal artery, or further back at the ophthalmic and internal carotid artery. Recognizing the symptoms and signs are important to help prevent permanent ischemic and irreversible blindness. Read More

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http://dx.doi.org/10.1097/APO.0000000000000287DOI Listing

CORRIGENDUM TO: CAPABILITIES OF THE ARADOS-WG03 REGIONAL NETWORK FOR LARGE-SCALE RADIOLOGICAL AND NUCLEAR EMERGENCY SITUATIONS IN ASIA.

Radiat Prot Dosimetry 2020 May 27. Epub 2020 May 27.

Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, South Korea.

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http://dx.doi.org/10.1093/rpd/ncaa079DOI Listing

The end of the artemisinin era - - we should aim at malaria eradication in Asia using free effective treatment.

Clin Infect Dis 2020 May 27. Epub 2020 May 27.

Univ Lyon, Malaria Research Unit, ICBMS, UMR 5246 CNRS INSA CPE, Lyon, France.

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http://dx.doi.org/10.1093/cid/ciaa625DOI Listing

Case Report: Serovar Paratyphi B Infection in a Febrile Ill Child during Enhanced Passive Surveillance in an Urban Slum in Mirpur, Dhaka.

Am J Trop Med Hyg 2020 May 26. Epub 2020 May 26.

icddr,b, (International Centre for Diarrhoeal Disease, Research, Bangladesh), Dhaka, Bangladesh.

Paratyphoid fever is one of the major causes of morbidity of febrile illnesses in endemic regions. We report a case of high-grade fever in an infant who was positive for serovar Paratyphi B (. Paratyphi B) both in blood and stool cultures. Read More

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http://dx.doi.org/10.4269/ajtmh.19-0958DOI Listing

Risk Factors for Scrub Typhus, Murine Typhus, and Spotted Fever Seropositivity in Urban Areas, Rural Plains, and Peri-Forest Hill Villages in South India: A Cross-Sectional Study.

Am J Trop Med Hyg 2020 May 26. Epub 2020 May 26.

Department of Clinical Microbiology, Christian Medical College, Vellore, India.

Scrub typhus and spotted fever group rickettsioses are thought to be common causes of febrile illness in India, whereas murine typhus is rarely tested for. This cross-sectional study explored the risk factors associated with scrub typhus, tick-borne spotted fever, and murine typhus seropositivity in three different geographical settings, urban, rural, and hill villages in Tamil Nadu, South India. We enrolled 1,353 participants living in 48 clusters. Read More

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http://dx.doi.org/10.4269/ajtmh.19-0642DOI Listing

Antimicrobial Resistance, Politics, and Practice in India.

Qual Health Res 2020 May 27:1049732320919088. Epub 2020 May 27.

Australian National University, Canberra, Australian Capital Territory, Australia.

India is considered the epicenter of the global antimicrobial resistance crisis, with unprecedented antimicrobial consumption, production, and "misuse." But the story of resistance in India is complicated-emerging from intersections of industrial pharmaceutical development, rationing/purchasing of health care, policy infrastructure, and dynamics of disadvantage. What looks like rampant, escalating antimicrobial misuse and a need for tighter controls over drugs and "prescribers," emerges as a complex social problem. Read More

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http://dx.doi.org/10.1177/1049732320919088DOI Listing

Patterns of Care and Outcome Analysis of Nasopharyngeal Carcinoma: An Indonesian Single Institution Study.

Asian Pac J Cancer Prev 2020 May 1;21(5):1481-1485. Epub 2020 May 1.

Department of Ear, Nose and Throat, Head and Neck Surgery, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

Background: Nasopharyngeal cancer is endemic to Southeast Asia. However, there is limited clinical evidence of nasopharyngeal cancer in Indonesia, which has the largest population in Southeast Asia.

Methods: Patterns of care and treatment outcomes in 428 patients with newly-diagnosed and pathologically-confirmed nasopharyngeal cancer were retrospectively analyzed. Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.5.1481DOI Listing

Genetic Variations of RAD51 and XRCC2 Genes Increase the Risk of Colorectal Cancer in Bangladeshi Population.

Asian Pac J Cancer Prev 2020 May 1;21(5):1445-1451. Epub 2020 May 1.

Department of Pharmacy, BGC Trust University Bangladesh, Chandanaish, Chittagong-4381, Bangladesh.

Objectives: In case of Bangladeshi population, no report is observed till now showing the genetic variations of RAD51 (rs1801320) and XRCC2 (rs3218536) genes polymorphism having association with colorectal cancer risk. For this reason the aim of this study is to ascertain their interrelation with colorectal cancer occurrence in Bangladeshi population.

Materials And Methods: A case control study was conducted where 200 colorectal cancer patients and 200 healthy volunteers were figured for this research using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.5.1445DOI Listing

An Asian Body to Tackle Cancers in Asia - The Asian National Cancer Centers Alliance.

Asian Pac J Cancer Prev 2020 May 1;21(5):1207-1212. Epub 2020 May 1.

National Cancer Center, Japan, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

The socioeconomic burden of cancer is growing rapidly in the Asian region, with a concentrated burden on low- and middle- income countries. The residents of this region, representing almost 60% of the global population, demonstrate an eclectic and complex nature, with huge disparities in ethnicity, sociocultural practices among others. The Asian National Cancer Centers Alliance (ANCCA) was established in 2005 by heads of several national cancer centers (NCCs) in the region to address common issues and concerns among Asian countries. Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.5.1207DOI Listing

[Analysis of chloroquine-resistant gene polymorphisms in imported into China in 2012 and 2018].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2020 Mar;32(2):174-180

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, National Health Commission, Shanghai 200025, China.

Objective: To detect the chloroquine-resistant molecular marker polymorphisms in imported into China, investigate the mutation types of chloroquine resistant transporter () gene at positions 72 to 76, and analyze the specificity of the specimens with different origins.

Methods: A total of 674 filter paper blood samples were collected from the National Malaria Diagnosis Reference Laboratory of China in 2012 and 2018. The amino acid po- sitions 72 to 76 of the gene on chromosome 7 were amplified using nested PCR assay and sequenced, and the sequencing results of the target gene fragment and the geographical region-specific prevalence of the mutations in the gene were analyzed. Read More

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http://dx.doi.org/10.16250/j.32.1374.2019277DOI Listing

[Pharmacological characteristics of chloroquine and suggestions for its use in treatment of coronavirus disease 2019 (COVID-19)].

Authors:
Q Gao

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2020 Apr;32(2):119-122

Jiangsu Institute of Parasitic Diseases; WHO Collaborating Center for Research and Training on Malaria Elimination; Key Laboratory of National Health Commission on Parasitic Disease Control and Prevention; Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Wuxi 214064, China.

A novel coronavirus disease (COVID-19) was identified in Wuhan City, Hubei Province of China by the end of 2019, and then, the disease spread across China and became a global pandemic. Nevertheless, there are no effective treatments or vaccines for COVID-19 until now. In addition to the treatment of patients with COVID-19, the China Medical Treatment Expert Group for COVID-19 is active to study and screen effective antiviral drugs, and has found that chloroquine, an old antimalarial,shows activity against SARS-CoV-2. Read More

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http://dx.doi.org/10.16250/j.32.1374.2020092DOI Listing

[Management of coronavirus disease 2019 (COVID-19): experiences from imported malaria control in China].

Authors:
Y B Liu J Cao

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2020 Mar;32(2):113-118

Jiangsu Institute of Parasitic Diseases, WHO Collaborating Center for Research and Training on Malaria Elimination, Key Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Wuxi 214064, China.

Currently, the local transmission of coronavirus disease 2019 (COVID-19) has been effectively contained in China; however, the epidemic situation of this highly infectious disease is more and more serious outside of China. Importation of COVID-19 cases from other countries and territories is therefore becoming a new challenge for the control of COVID-19 in China. Malaria was once widely epidemic in China. Read More

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http://dx.doi.org/10.16250/j.32.1374.2020063DOI Listing

Clinical characteristics of hidradenitis suppurativa patients in Okinawa, Japan: Differences between East Asia and Western countries.

J Dermatol 2020 May 26. Epub 2020 May 26.

Department of Dermatology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan.

Hidradenitis suppurativa (HS) is a long-term inflammatory follicular disease. In Western countries, the prevalence of HS has been estimated to be 0.1-4% in the general population. Read More

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http://dx.doi.org/10.1111/1346-8138.15411DOI Listing

Construction and Characterization of a Novel Recombinant Attenuated and Replication-Deficient Candidate Human Adenovirus Type 3 Vaccine: "Adenovirus Vaccine Within an Adenovirus Vector".

Virol Sin 2020 May 26. Epub 2020 May 26.

Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.

Human adenoviruses (HAdVs) are highly contagious and result in large number of acute respiratory disease (ARD) cases with severe morbidity and mortality. Human adenovirus type 3 (HAdV-3) is the most common type that causes ARD outbreaks in Asia, Europe, and the Americas. However, there is currently no vaccine approved for its general use. Read More

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http://dx.doi.org/10.1007/s12250-020-00234-1DOI Listing

Effects of Growth Phase and Ultraviolet-B Pretreatment in Perilla Leaves on the Two-Spotted Spider Mite.

Environ Entomol 2020 May 27. Epub 2020 May 27.

Laboratory of Ecological Information, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

Perilla, Perilla frutescens (L.) Britton var. crispa (Thunb. Read More

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http://dx.doi.org/10.1093/ee/nvaa055DOI Listing

Transcriptome Assembly, Gene Annotation and SSR Marker Development in the Moon Seed Genus (Menispermaceae).

Front Genet 2020 8;11:380. Epub 2020 May 8.

Laboratory of Systematic and Evolutionary Botany and Biodiversity, College of Life Sciences, Zhejiang University, Hangzhou, China.

The moonseed genus L. (Menispermaceae) is disjunctly distributed in East Asia and eastern North America. Although has important medicinal value, genetic and genomic information is scarce, with very few available molecular markers. Read More

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http://dx.doi.org/10.3389/fgene.2020.00380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227793PMC

Genome Wide Assessment of Genetic Variation and Population Distinctiveness of the Pig Family in South Africa.

Front Genet 2020 7;11:344. Epub 2020 May 7.

Biotechnology Platform, Agricultural Research Council, Onderstepoort, South Africa.

Genetic diversity is of great importance and a prerequisite for genetic improvement and conservation programs in pigs and other livestock populations. The present study provides a genome wide analysis of the genetic variability and population structure of pig populations from different production systems in South Africa relative to global populations. A total of 234 pigs sampled in South Africa and consisting of village ( = 91), commercial ( = 60), indigenous ( = 40), Asian ( = 5) and wild ( = 38) populations were genotyped using Porcine SNP60K BeadChip. Read More

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http://dx.doi.org/10.3389/fgene.2020.00344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221027PMC

Molecular Characteristics of Collected From Humans in Hainan, China.

Front Microbiol 2020 7;11:778. Epub 2020 May 7.

Sanya People's Hospital, Sanya, China.

Melioidosis is a common infectious disease in Southeast Asia and Northern Australia. In Hainan, several cases have been reported, but no systematic study has yet been done on the molecular epidemiology profiles of the organism. An investigation of the molecular epidemiology links and population structure of would help to better understand the clonally of the isolates and differences among them. Read More

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http://dx.doi.org/10.3389/fmicb.2020.00778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223694PMC

Traditional Chinese Medicine in Depression Treatment: From Molecules to Systems.

Front Pharmacol 2020 7;11:586. Epub 2020 May 7.

School of Life Sciences, Guangzhou University, Guangzhou, China.

Depression is a multigenetic or multifactorial syndrome. The central neuron system (CNS)-orientated, single target, and conventional antidepressants are insufficient and far from ideal. Traditional Chinese Medicine (TCM) has historically been used to treat depression up till today, particularly in Asia. Read More

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http://dx.doi.org/10.3389/fphar.2020.00586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221138PMC

Fisheries interactions and the challenges for target and nontargeted take on shark conservation in the Mexican Pacific.

Adv Mar Biol 2020 4;85(1):39-69. Epub 2020 May 4.

Instituto Nacional de Pesca y Acuacultura, National Fisheries and Aquaculture Institute, Centro Regional de Investigación Pesquera Ensenada, Ensenada, Baja California, México.

Sharks have been of great cultural and socioeconomic importance in Mexico since the late 19th century, when the first fisheries were prosecuted in the Gulf of California to export fins to China. Mexican shark and ray fisheries are classified mainly by the size of the fishing vessel and include small- (7.5-10m), medium- (10-27m), and large-sized (>27m) fisheries. Read More

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http://dx.doi.org/10.1016/bs.amb.2020.03.001DOI Listing

Impact of family physician integrated care program on decreasing utilization of emergency department visit and hospital admission: a population-based retrospective cohort study.

BMC Health Serv Res 2020 May 26;20(1):470. Epub 2020 May 26.

Department of Health Services Administration, China Medical University, 91, Hsueh-Shih Road, Taichung, Taiwan, 40402.

Background: Hospital admission and emergency department(ED) visits are a massive burden in medical expenditures. In 2003, the Taiwanese government developed Family Physician Integrated Care Program (FPIC) to increase the quality of primary care and decrease medical expenditures. This study's goals were to determine whether FPIC decreased hospital admissions and ED visits and identify the factors influencing the outcomes. Read More

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http://dx.doi.org/10.1186/s12913-020-05347-7DOI Listing

Discovery of significant porcine SNPs for swine breed identification by a hybrid of information gain, genetic algorithm, and frequency feature selection technique.

BMC Bioinformatics 2020 May 26;21(1):216. Epub 2020 May 26.

National Biobank of Thailand, National Science and Technology Development Agency, Khong Luang, 12120, Thailand.

Background: The number of porcine Single Nucleotide Polymorphisms (SNPs) used in genetic association studies is very large, suitable for statistical testing. However, in breed classification problem, one needs to have a much smaller porcine-classifying SNPs (PCSNPs) set that could accurately classify pigs into different breeds. This study attempted to find such PCSNPs by using several combinations of feature selection and classification methods. Read More

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http://dx.doi.org/10.1186/s12859-020-3471-4DOI Listing

Neutrophils Modulate Fibroblast Function and Promote Healing and Scar Formation after Murine Myocardial Infarction.

Int J Mol Sci 2020 May 23;21(10). Epub 2020 May 23.

Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, 52074 Aachen, Germany.

Aim: Recruitment of neutrophils to the heart following acute myocardial infarction (MI) initiates inflammation and contributes to adverse post-infarct left ventricular (LV) remodeling. However, therapeutic inhibition of neutrophil recruitment into the infarct zone has not been beneficial in MI patients, suggesting a possible dual role for neutrophils in inflammation and repair following MI. Here, we investigate the effect of neutrophils on cardiac fibroblast function following MI. Read More

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http://dx.doi.org/10.3390/ijms21103685DOI Listing
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