47,508 results match your criteria Ascites

Unfolding the Apoptotic Mechanism of Antioxidant Enriched-Leaves of Tabebuia pallida (Lindl.) Miers in EAC Cells and Mouse Model.

J Ethnopharmacol 2021 Jun 9:114297. Epub 2021 Jun 9.

Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh. Electronic address:

Ethnopharmacological Relevance: Tabebuia pallida (Lindl.) Miers (T. pallida) is a well-known native Caribbean medicinal plant. Read More

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Prognostic performance of seven biomarkers compared to liver biopsy in early alcohol-related liver disease.

J Hepatol 2021 Jun 9. Epub 2021 Jun 9.

Department of Gastroenterology and Hepatology, Odense University Hospital, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.

Background & Aims: Alcohol is the most common cause of liver-related mortality and morbidity. We therefore aimed to assess and compare the prognostic performance of elastography and blood-based markers to predict time to the first liver-related event, severe infection, and all-cause mortality in patients with a history of excess drinking.

Methods: Prospective cohort study of patients with early, compensated alcohol-related liver disease. Read More

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Respiratory Failure in Noonan Syndrome Treated by Microsurgical Thoracic Duct-Venous Anastomosis.

Ann Thorac Surg 2021 Jun 8. Epub 2021 Jun 8.

Division of Plastic Surgery, Department of Surgery, University of Pennsylvania. Electronic address:

Noonan Syndrome is a disorder characterized by central and peripheral lymphatic conducting anomalies, leading to chylothorax, chylous ascites, and metabolic derangement. Novel imaging modalities including dynamic contrast magnetic resonance lymphangiography (DCMRL) and intranodal lymphangiography have allowed for increased visualization of lymphatic pathology. We describe the first study of a 61-year-old male with Noonan syndrome who developed severe pulmonary insufficiency and chylothoraces. Read More

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Tim-4 cavity-resident macrophages impair anti-tumor CD8 T cell immunity.

Cancer Cell 2021 May 29. Epub 2021 May 29.

Departments of Surgery and Pathology, Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.

Immune checkpoint blockade (ICB) has been a remarkable clinical advance for cancer; however, the majority of patients do not respond to ICB therapy. We show that metastatic disease in the pleural and peritoneal cavities is associated with poor clinical outcomes after ICB therapy. Cavity-resident macrophages express high levels of Tim-4, a receptor for phosphatidylserine (PS), and this is associated with reduced numbers of CD8 T cells with tumor-reactive features in pleural effusions and peritoneal ascites from patients with cancer. Read More

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Ovarian dysgerminoma with pseudo-Meigs syndrome: A case report.

Medicine (Baltimore) 2021 Jun;100(23):e26319

Forensic and Pathology Laboratory, Jiaxing University Medical College, Jiaxing, ZJ, China.

Rationale: Dysgerminoma is a rare malignant tumor of the ovary, more frequently occurring in young women. The main signs of pseudo-Meigs syndrome (PMS) are ascites and hydrothorax accompanying benign or malignant ovarian tumors (no fibroma or fibroma-like tumor).

Patient Concerns: A 19-year-old woman with fever and chest tightness for 2 days. Read More

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Correlation of gastrointestinal perforation location and amount of free air and ascites on CT imaging.

Abdom Radiol (NY) 2021 Jun 10. Epub 2021 Jun 10.

Department of Diagnostic, Interventional and Pediatric Radiology, INSELGROUP, Radiology Division SLS, University of Bern, Tiefenaustrasse 112, 3004, Bern, Switzerland.

Purpose: To analyze the amount of free abdominal gas and ascites on computed tomography (CT) images relative to the location of a perforation.

Methods: We retrospectively included 172 consecutive patients (93:79 = m:f) with GIT perforation, who underwent abdominal surgery (ground truth for perforation location). The volume of free air and ascites were quantified on CT images by 4 radiologists and a semiautomated software. Read More

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Survival predictors of Lu-Dotatate peptide receptor radionuclide therapy (PRRT) in patients with progressive well-differentiated neuroendocrine tumors (NETS).

J Cancer Res Clin Oncol 2021 Jun 10. Epub 2021 Jun 10.

Medical Imaging Department, Division of Nuclear Medicine, Victoria Hospital, London Health Sciences Centre, University of Western Ontario, 800 Commissioners Road East, PO Box 5010, London, ON, N6A 5W9, Canada.

Purpose: Lu-Dotatate is an emerging treatment modality for patients with unresectable or metastatic well-differentiated NETs. This study examines survival predictors in patients who received Lu-Dotatate.

Methods: A retrospective single-center review was conducted, examining 47 individuals with progressive well-differentiated NETs treated with Lu-Dotatate (four induction cycles of 5. Read More

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Production, structural and biochemical characterization relevant to antitumor property of acidic exopolysaccharide produced from Bacillus sp. NRC5.

Arch Microbiol 2021 Jun 10. Epub 2021 Jun 10.

Department of Medicinal and Aromatic Plants Research, National Research Centre, 33 St. El-Buhouth, Dokki, Cairo, Egypt.

This study targeted the production of exopolysaccharide from Bacillus sp. NRC5 grown in Egyptian seawater to use it as natural antitumor therapy. The biological activities of selected exopolysaccharide (BEPS) as an antioxidant, anti-inflammatory and anticancer have been studied. Read More

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Rare Fetus-in-Fetu: Experience From a Large Tertiary Pediatric Referral Center.

Front Pediatr 2021 24;9:678479. Epub 2021 May 24.

Department of Pediatric Surgery, Maternal and Child Health Hospital of Hubei, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Fetus-in-fetu (FIF) is an extremely rare disease, and most prior publications are single case reports. Here, we describe the clinical characteristics, imaging manifestations, and the treatment and related complications of FIF from a large tertiary pediatric referral center. After institutional review board approval, patients with a diagnosis of FIF between January 2010 and November 2019 were further selected and reexamined. Read More

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Portal vein obstruction after pediatric liver transplantation: A systematic review of current treatment strategies.

Transplant Rev (Orlando) 2021 May 29;35(4):100630. Epub 2021 May 29.

Division of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Electronic address:

Introduction: Portal vein obstruction (PVO) is a significant vascular complication after liver transplantation (LT) in pediatric patients. Current treatment strategies include percutaneous transluminal angioplasty (PTA), with or without stent placement, mesorex bypass (MRB), splenorenal shunt, mesocaval shunt, endovascular recanalization (EVR), splenic artery embolization and splenectomy. However, specific characteristics of patients undergoing intervention and selection of individual treatment and its efficacy have remained unclear. Read More

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Autoimmune Enteropathy Presenting as Ascites in a Patient With Cirrhosis.

Inflamm Bowel Dis 2021 Jun 9. Epub 2021 Jun 9.

From the Emory University School of Medicine, Atlanta, Georgia, USA.

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Outcome of patients with acute severe necrotizing pancreatitis in a dedicated hepato-biliary unit of Pakistan.

Pak J Med Sci 2021 May-Jun;37(3):639-645

Rafi ud Din, FCPS Medicine, FCPS Gastroenterology, Consultant Gastroenterology, Combined Military Hospital, Quetta, Pakistan.

Objective: To analyze the management of severe necrotizing pancreatitis in a specialized center of a lower middle-income country, Pakistan using multiple outcome measures.

Methods: All the patients in this prospective observational study with severe necrotizing pancreatitis being referred to Pak Emirates Military Hospital from January 2017 to December 2019 were followed over the course of their admission. Demographic data and disease outcomes were duly noted. Read More

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The incidence and outcome of postoperative hepatic encephalopathy in patients with cirrhosis.

United European Gastroenterol J 2021 Jun 8. Epub 2021 Jun 8.

Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA.

Background: Cirrhosis is associated with increased perioperative risks related to hepatic decompensation. However, data are lacking regarding the incidence and outcomes of postoperative hepatic encephalopathy (HE).

Objective: To determine the incidence of HE postoperatively, factors associated with its development, and its association with in-hospital mortality. Read More

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Anticancer activities of parthenolide in primary effusion lymphoma preclinical models.

Mol Carcinog 2021 Jun 8. Epub 2021 Jun 8.

Faculty of Sciences, GSBT Laboratory, R. Hariri Campus, Lebanese University, Hadath, Lebanon.

The sesquiterpene lactone parthenolide is a major component of the feverfew medicinal plant, Tanacetum parthenium. Parthenolide has been extensively studied for its anti-inflammatory and anticancer properties in several tumor models. Parthenolide's antitumor activities depend on several mechanisms but it is mainly known as an inhibitor of the nuclear factor-κB (NF-κB) pathway. Read More

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Self-assembling peptide hydrogel SPG-178 as a pancreatic fistula-preventing agent.

Langenbecks Arch Surg 2021 Jun 7. Epub 2021 Jun 7.

Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan.

Purpose: Pancreatic fistula (PF) is a common and challenging complication after pancreatic surgery. The aim of this study was to investigate the efficacy of a new method for preventing PF utilizing self-assembling peptide hydrogel SPG-178 as a preclinical study.

Methods: The degradability of SPG-178 was confirmed by mixing it with protease. Read More

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Longitudinal national-level monitoring of on-farm broiler welfare identifies consistently poorly performing farms.

Sci Rep 2021 Jun 7;11(1):11928. Epub 2021 Jun 7.

Bristol Veterinary School, University of Bristol, Langford, Avon, Bristol, BS40 5DU, UK.

A range of welfare outcome measures relating to on-farm welfare are monitored in UK slaughterhouses to check compliance with the European Broiler Directive. A national dataset from 438,155 batches of chickens between 2010 and 2014 and from 228,795 batches between 2016 and 2018 was analysed. The data contained information about 3. Read More

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Sharma's parachute sign a new laparoscopic sign in abdomino pelvic tuberculosis.

Indian J Tuberc 2021 Jul 9;68(3):389-395. Epub 2019 Aug 9.

Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi-110029, India. Electronic address:

Aims: To demonstrate a new laparoscopic sign "Sharma's Parachute sign" in abdominopelvic tuberculosis in women with infertility.

Methods: A total of 104 women who were diagnosed to have abdominopelvic tuberculosis, on endometrial sampling or on laparoscopy were enrolled in this ongoing study on tuberculosis in infertility. A new laparoscopic "Sharma's parachute sign" was looked for in these cases on laparoscopy. Read More

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Infant with "Ascites".

J Pediatr 2021 Jun 4. Epub 2021 Jun 4.

Department of Pediatric Surgery, Apollo BGS Hospitals, Mysuru, Karnataka, India.

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Frailty in Nonalcoholic Fatty Liver Cirrhosis: A Comparison with Alcoholic Cirrhosis, Risk Patterns, and Impact on Prognosis.

Can J Gastroenterol Hepatol 2021 21;2021:5576531. Epub 2021 May 21.

Gastroenterology and Hepatology Subdivision, 5 Department of Medicine, Comenius University Faculty of Medicine, University Hospital Bratislava, Ruzinovska 6, Bratislava 82606, Slovakia.

Background: Physical frailty increases susceptibility to stressors and predicts adverse outcomes of cirrhosis. Data on disease course in different etiologies are scarce, so we aimed to compare the prevalence and risk factors of frailty and its impact on prognosis in nonalcoholic fatty liver (NAFLD) and alcoholic (ALD) cirrhosis. . Read More

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An Autopsy Case of Multicentric Castleman Disease Presenting with Severe Jaundice.

Intern Med 2021 Jun 5. Epub 2021 Jun 5.

¹Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Japan.

A 70-year-old man with multicentric Castleman disease (MCD) was admitted to our hospital with jaundice and ascites. Elevations in his bilirubin and interleukin-6 levels were noted, and computed tomography revealed hepatic atrophy and portal vein and bile duct disorders. Steroid therapy was started for MCD, but he died of hepatic failure. Read More

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Eosinophilic ascites as an uncommon presentation of eosinophilic gastroenteritis: A case report.

Arab J Gastroenterol 2021 Jun 2. Epub 2021 Jun 2.

Department of Hepatogastroenterology, Theodor Bilharz Research Institute, Giza, Egypt; Department of Pathology, Theodor Bilharz Research Institute, Giza, Egypt; Department of Tropical Medicine and Hepatogastroenterology, Faculty of Medicine, Cairo University, Cairo, Egypt; Service d'Hépatologie, Hôpital Beaujon, APHP, Clichy-la-Garenne, CRI-UMR 1149, Inserm and Université de Paris, Paris, France.

Background: Eosinophilic gastroenteritis (EGE) is defined by the presence of gastrointestinal symptoms, with an abnormal eosinophilic infiltrate of the intestine wall and exclusion of other causes of secondary eosinophilia. EGE has three clinical presentations, depending on the depth of eosinophilic infiltration of the bowel wall. It individualizes into three types, namely mucosal, muscular, and subserosal. Read More

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Diagnosis of malignant versus tuberculous ascites using tumor markers and globulin ratios in serum and ascites: A Fisher discriminant model.

Arab J Gastroenterol 2021 Jun 2. Epub 2021 Jun 2.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China. Electronic address:

Background And Study Aims: This study was conducted to investigate the significance of tumor and biochemical markers in serum and ascitic fluid in the differential diagnosis of tuberculous and malignant ascites.

Patients And Methods: Based on findings from natural orifice transluminal endoscopic surgery and postoperative pathology or cytology of 63 patients, they were divided into the malignant group (31 patients) and the tuberculous group (32 patients). Levels of tumor markers, albumin, globulin, and lactate dehydrogenase were measured simultaneously. Read More

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Role of Tissue Plasminogen Activator in Loculated Ascites.

ACG Case Rep J 2021 May 1;8(5):e00590. Epub 2021 Jun 1.

Universal Health Services Southern California Medical Education Consortium, Internal Medicine Residency Program, Temecula, CA.

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Proteomic Analysis of Malignant Ascites From Patients With Pancreatic Ductal Adenocarcinoma.

Anticancer Res 2021 Jun;41(6):2895-2900

Department of Gastroenterological Surgery, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan;

Background/aim: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignant tumor. Research using an innovative research approach is needed to identify effective biomarkers or therapeutic targets for PDAC. We aimed to identify proteins related to the peritoneal dissemination of PDAC. Read More

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Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization.

J Exp Clin Cancer Res 2021 Jun 3;40(1):182. Epub 2021 Jun 3.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

Background: Aberrant lipogenicity and deregulated autophagy are common in most advanced human cancer and therapeutic strategies to exploit these pathways are currently under consideration. Group III Phospholipase A2 (sPLA2-III/PLA2G3), an atypical secretory PLA2, is recognized as a regulator of lipid metabolism associated with oncogenesis. Though recent studies reveal that high PLA2G3 expression significantly correlates with poor prognosis in several cancers, however, role of PLA2G3 in ovarian cancer (OC) pathogenesis is still undetermined. Read More

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Positive Psychosocial Factors and Oxytocin in the Ovarian Tumor Microenvironment.

Psychosom Med 2021 Jun;83(5):417-422

From the Department of Psychological and Brain Sciences (Cuneo, Schrepf, Lutgendorf), University of Iowa, Iowa City, Iowa; Department of Psychology (Szeto, McCabe), University of Miami, Coral Gables, Florida; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology (Thaker), Washington University School of Medicine, St Louis, Missouri; Holden Comprehensive Cancer Center (Goodheart, Lutgendorf) and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology (Goodheart, Lutgendorf), University of Iowa, Iowa City, Iowa; Department of Medicine, Division of Hematology/Oncology and Molecular Biology Institute, David Geffen School of Medicine (Cole), University of California, Los Angeles; Departments of Gynecologic Oncology, Cancer Biology and Center for RNA Interference and Noncoding RNA (Sood), University of Texas MD Anderson Cancer Center, Houston, Texas; and Diabetes Research Institute, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Miller School of Medicine (Mendez), University of Miami, Coral Gables, Florida.

Objective: Clinical ovarian cancer research shows relationships between psychosocial factors and disease-promoting aspects of the stress response (e.g., norepinephrine and cortisol). Read More

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The impact of elastography with virtual touch quantification of future remnant liver before major hepatectomy.

Quant Imaging Med Surg 2021 Jun;11(6):2572-2585

Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Background: Liver elastography with virtual touch quantification (VTQ) measures the velocity of the shear wave generated by a short-duration acoustic force impulse, with values expressed in units of velocity (m/s). VTQ can evaluate right or left hepatic lobes separately. VTQ might be appropriate for the evaluation of future remnant liver after hepatectomy. Read More

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Mitochondria in epithelial ovarian carcinoma exhibit abnormal phenotypes and blunted associations with biobehavioral factors.

Sci Rep 2021 Jun 2;11(1):11595. Epub 2021 Jun 2.

Division of Behavioral Medicine, Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.

Malignant tumor cells exhibit mitochondrial alterations and are also influenced by biobehavioral processes, but the intersection of biobehavioral factors and mitochondria in malignant tumors remains unexplored. Here we examined multiple biochemical and molecular markers of mitochondrial content and function in benign tissue and in high-grade epithelial ovarian carcinoma (EOC) in parallel with exploratory analyses of biobehavioral factors. First, analysis of a publicly-available database (n = 1435) showed that gene expression of specific mitochondrial proteins in EOC is associated with survival. Read More

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Primary pneumococcal peritonitis with a fulminant course.

Vnitr Lek 2021 ;67(E-2):34-37

Introduction: Primary peritonitis is an inflammation of the peritoneal cavity in the absence of a localized intra-abdominal source. It is included in the differential diagnosis of acute abdomen and can be potentially life-threatening. Pneumococci were a frequent pathogen causing primary peritonitis especially in the preantibiotic era. Read More

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Real-World Experience of the One-Year Efficacy of Rifaximin Add-On to Lactulose Is Superior to Lactulose Alone in Patients with Cirrhosis Complicated with Recurrent Hepatic Encephalopathy in Taiwan.

J Pers Med 2021 May 27;11(6). Epub 2021 May 27.

Division of Hepatology, Department of Gastroenterology and Hepatology, Chang-Gung Memorial Hospital, Linkou Medical Center, Taoyuan 33305, Taiwan.

Background: Hepatic encephalopathy (HE), a neuropsychiatric complication of decompensated cirrhosis, is associated with high mortality and high risk of recurrence. Rifaximin add-on to lactulose for 3 to 6 months is recommended for the prevention of recurrent episodes of HE after the second episode. However, whether the combination for more than 6 months is superior to lactulose alone in the maintenance of HE remission is less evident. Read More

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