44,121 results match your criteria Ascites


The Association of D-dimer and Spontaneous Hemorrhagic Ascites with Outcomes in Cirrhosis: a Retrospective Study.

Clin Lab 2019 Jan;65(1)

Background: Cirrhotic patients with hemorrhagic ascites have significant morbidity and mortality. This study aims to determine the relationship between D-dimer values and hemorrhagic ascites in cirrhotic patients and analyze its predictive value.

Methods: This retrospective study screened 572 consecutive cirrhotic patients with ascites and hemorrhagic ascites (defined as red blood cells (RBC) in ascitic fluid ≥ 10,000/µL) during a 72-month period. Read More

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http://dx.doi.org/10.7754/Clin.Lab.2018.180548DOI Listing
January 2019

Reversing platinum resistance in ovarian cancer multicellular spheroids by targeting Bcl-2.

Onco Targets Ther 2019 29;12:897-906. Epub 2019 Jan 29.

Department of Chemotherapy, Cancer Center, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China,

Purpose: Peritoneal metastasis is the most common pathway for the spread of ovarian cancer. Ovarian cancer cells in ascites prefer to aggregate into the more chemoresistant multicellular spheroids (MCSs), leading to treatment failure and disease recurrence. We previously established a suspension MCS model of ovarian cancer cells in vitro and found that the MCS cells acquired drug resistance to cisplatin. Read More

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http://dx.doi.org/10.2147/OTT.S187015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357888PMC
January 2019

Diastolic dysfunction on echocardiography does not predict survival after transjugular intrahepatic portosystemic stent-shunt in patients with cirrhosis.

Aliment Pharmacol Ther 2019 Feb 17. Epub 2019 Feb 17.

Liver Unit, Queen Elizabeth University Hospital, Birmingham, UK.

Background: Cardiac dysfunction is frequently observed in patients with cirrhosis. There remains a paucity of data from routine clinical practice regarding the role of echocardiography in the pre-assessment of transjugular intrahepatic portosystemic stent-shunt.

Aim: Our study aimed to investigate if echocardiography parameters predict outcomes after transjugular intrahepatic portosystemic stent-shunt insertion in cirrhosis. Read More

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http://dx.doi.org/10.1111/apt.15164DOI Listing
February 2019

Recanalization of Chronic Portal Vein Occlusion in Pediatric Liver Transplant Patients.

J Vasc Interv Radiol 2019 Feb 14. Epub 2019 Feb 14.

Department of Interventional Radiology, Texas Children's Hospital, 6621 Fannin Street, Houston, TX, 77030. Electronic address:

Purpose: To evaluate technical and clinical success and report long-term outcomes of portal vein (PV) recanalization in pediatric orthotopic liver transplant (OLT) patients with chronic PV occlusion.

Materials And Methods: This is a retrospective review of 15 OLT patients (5 males) with chronic PV occlusion who underwent PV recanalization (33 procedures) between October 2011 and February 2018. Median age was 4. Read More

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http://dx.doi.org/10.1016/j.jvir.2018.08.020DOI Listing
February 2019

Addition of Carvedilol to Gastric Variceal Obturation Does Not Decrease Recurrence of Gastric Variceal Bleeding in Patients With Cirrhosis.

Clin Gastroenterol Hepatol 2019 Feb 14. Epub 2019 Feb 14.

School of Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Background & Aims: Gastric variceal bleeding (GVB) frequently recurs after hemostasis by gastric variceal obturation (GVO). We performed a multicenter, randomized controlled trial to determine the efficacy of carvedilol plus GVO in secondary prophylaxis of GVB.

Methods: We performed a prospective study of 121 patients with cirrhosis (ages 20-80 years) with GVB proven by endoscopy within 24 hours of bleeding and stable hemodynamics for at least 3 days after initial GVO. Read More

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http://dx.doi.org/10.1016/j.cgh.2019.02.021DOI Listing
February 2019

A simple and rapid colorimetric bacteria detection method based on bacterial inhibition of glucose oxidase-catalyzed reaction.

Talanta 2019 May 11;197:304-309. Epub 2019 Jan 11.

State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China. Electronic address:

Rapid and sensitive detection of live bacteria is crucial in the realm of clinical diagnosis, food industry and environmental quality control. A portable, feasible and cost-effective platform which enables rapid and accurate live bacteria detection is still challenging. Herein, we present a Bacterial Inhibition of GOX-catalyzed Reaction (BIGR) method for rapid and broad-spectrum detection of live bacteria, which results in a visible color change without any complex instrumentations. Read More

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http://dx.doi.org/10.1016/j.talanta.2019.01.039DOI Listing
May 2019
1 Read

Development and Validation of a Risk-Calculator for Adverse Perioperative Outcomes for Women with Ovarian Cancer.

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Columbia University College of Physicians and Surgeons; Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons; New York Presbyterian Hospital. Electronic address:

Background: Primary cytoreduction followed by platinum based chemotherapy is the primary treatment for advanced ovarian cancer. However neoadjuvant chemotherapy followed by interval debulking is an alternative option, particularly in those who may be poor surgical candidates.

Objective: The objective of this study was to determine factors associated with short term, significant perioperative morbidity and mortality for women undergoing surgery for ovarian cancer and to create a nomogram to predict the risk of adverse perioperative outcomes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193036
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http://dx.doi.org/10.1016/j.ajog.2019.02.019DOI Listing
February 2019
3 Reads

Stem extract of Tabebuia chrysantha induces apoptosis by targeting sEGFR in Ehrlich Ascites Carcinoma.

J Ethnopharmacol 2019 Feb 12. Epub 2019 Feb 12.

Pharmaceutical Analysis Laboratory, SIMS College of Pharmacy, Guntur, India. Electronic address:

Ethnopharmacological Relevance: The plant Tabebuia chrysantha (Jaq.) Nicholson (Bignoniaceae) is commonly known as "Golden Goddess" in the Southern part of India and "Golden Trumpet Tree " in Central America. Stems of this plant have been traditionally used for antioxidant, anti-inflammatory, antimicrobial and anticancer actions. Read More

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http://dx.doi.org/10.1016/j.jep.2019.02.023DOI Listing
February 2019
1 Read

Correlation of Serum and Ascitic Fluid Soluble Form Urokinase Plasminogen Activator Receptor Levels With Patient Complications, Disease Severity, Inflammatory Markers, and Prognosis in Patients With Severe Acute Pancreatitis.

Pancreas 2019 Feb 14. Epub 2019 Feb 14.

From the Intensive Care Unit, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Objectives: The aim of the study was to investigate the correlation of serum and ascitic fluid soluble form urokinase plasminogen activator receptor (suPAR) levels with patients' complications, disease severity, inflammatory markers, and prognosis in patients with severe acute pancreatitis (SAP).

Methods: Fifty patients with SAP, 47 patients with mild acute pancreatitis, and 50 healthy controls were enrolled. Serum samples were obtained from all participants after enrollment; meanwhile, ascitic fluid samples were collected from 20 patients with SAP who developed ascites. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001247DOI Listing
February 2019

The yield and safety of screening colonoscopy in patients evaluated for liver transplantation.

Hepatology 2019 Feb 14. Epub 2019 Feb 14.

Department of Gastroenterology and Hepatology, Erasmus MC University Hospital, Rotterdam, Netherlands.

Colorectal cancer screening with colonoscopy is commonly used in candidate patients for liver transplantation. We initiated this study to define the risk-benefit ratio of performing screening colonoscopy in this population. A retrospective observational study of all consecutive patients undergoing colonoscopy during pre-liver transplantation screening between 2004-2017 was conducted. Read More

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http://dx.doi.org/10.1002/hep.30562DOI Listing
February 2019

Pressurized intraperitoneal aerosol chemotherapy procedure for nonresectable peritoneal carcinomatosis: First Indian study.

South Asian J Cancer 2019 Jan-Mar;8(1):27-30

Department of Surgical Oncology, Manipal Hospital, Bengaluru, Karnataka, India.

Background: Peritoneal carcinomatosis (PC) is a common evolution of abdominal cancers and is associated with poor prognosis. A few selected patients have option of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, but majority who are not eligible for curative approach can undergo pressurized intraperitoneal aerosol chemotherapy (PIPAC). It is an emerging field of research with major therapeutic potential. Read More

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http://journal.sajc.org/text.asp?2019/8/1/27/250100
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http://dx.doi.org/10.4103/sajc.sajc_92_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348786PMC
February 2019
1 Read

Long Term Survival of Patients Undergoing TIPS in Budd-Chiari Syndrome.

J Clin Exp Hepatol 2019 Jan-Feb;9(1):56-61. Epub 2018 Mar 1.

Consultant, Department of Vascular and Interventional Radiology, Tan Tock Seng Hospital, Singapore.

Background: There has been significant improvement in understanding the etiology and management of Budd-Chiari Syndrome (BCS). Patients with chronic or acute-on-chronic BCS need radiological interventions in the form of angioplasty, hepatic vein/inferior vena cava stenting or Transjugular Intrahepatic Portosystemic Shunt (TIPS). Data regarding the long term follow up of patients undergoing TIPS is limited. Read More

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http://dx.doi.org/10.1016/j.jceh.2018.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363956PMC
March 2018
1 Read

Results of Sofosbuvir Plus Ribavirin in Patients With Hepatitis C Related Decompensated Cirrhosis.

J Clin Exp Hepatol 2019 Jan-Feb;9(1):4-12. Epub 2018 Mar 6.

Institute of Liver, Gastroenterology, & Panceatico-Biliary Sciences, Sir Ganga Ram Hospital, New Delhi, India.

Background: Sofosbuvir (SOF), a direct acting antiviral, has revolutionized the treatment of chronic Hepatitis C Virus (HCV) infection. However, data is scarce about efficacy of SOF plus Ribavarin (RBV) in Indian patients with decompensated cirrhosis. We evaluated the efficacy of SOF plus RBV in decompensated cirrhosis, and compared the outcome with compensated cirrhosis and non-cirrhotics. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09736883183004
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http://dx.doi.org/10.1016/j.jceh.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363947PMC
March 2018
2 Reads

[Postoperative Recurrence of Pancreatic Cancer Successfully Treated with the Gemcitabine plus Oxaliplatin Regimen Resulting in Long-Term Survival-ACase Report].

Gan To Kagaku Ryoho 2019 Jan;46(1):142-144

Dept. of Surgery, Odawara Municipal Hospital.

A 38-year-old woman who presented with complaints of back pain was diagnosed with cancer of the pancreatic body. Since invasion of the celiac artery/superior mesenteric artery was suspected, she was referred to our department for chemotherapy. She received 4 courses of gemcitabine plus S-1(GS), and she underwent distal pancreatectomy with en bloc celiac axis resection/portal vein resection/reconstruction using a left renal vein graft(OP-CAR). Read More

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January 2019

[A Case of Small Bowel Perforation Due to Lung Cancer Metastasis].

Gan To Kagaku Ryoho 2019 Jan;46(1):127-129

Dept. of Surgery, Fukuoka Tokushukai Hospital.

A 79-year-old man was diagnosed with Stage ⅢB(T4N2M0)adenocarcinoma of the lung, administered. He suddenly developed abdominal pain with muscle guarding and rebound tenderness. An abdominal computed tomography scan revealed a thickened small bowel wall and mesenteric mass, as well as massive ascites and free air. Read More

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January 2019

[A Case of Robot-Assisted Conversion Surgery for Gastric Cancer with Peritoneal Dissemination That Responded to Intravenous and Intraperitoneal Paclitaxel Combined with S-1 Chemotherapy].

Gan To Kagaku Ryoho 2019 Jan;46(1):112-114

Dept. of Surgery, Fujita Health University.

This case involved a 69-year-old female patient with peritoneal dissemination of an advanced gastric cancer. She underwent chemotherapy comprisingintravenous and intraperitoneal paclitaxel combined with S-1. After 20 courses, a staging laparoscopy was performed, and pathological analysis of the peritoneal dissemination and cytologic analysis of ascites fluid yielded negative results. Read More

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January 2019

[Curatively Resected Stage ⅣGastric Cancer with Positive Peritoneal Cytology Due to SOX Therapy-A Case Report].

Gan To Kagaku Ryoho 2019 Jan;46(1):71-74

Dept. of Digestive Surgery, Kawaguchi Municipal Medical Center.

A 70-year-old man with epigastralgia who initially visited a local hospital was referred to us for further examination. Gastrointestinal endoscopy exhibited a type 3 tumor of the stomach from the body to the antrum(adenocarcinoma, por1). Contrast-enhanced CT revealed thickness in the wall of the gastric body with bulky lymph nodes and ascites. Read More

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January 2019
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The dynamic side of the Warburg effect: glycolytic intermediate storage as buffer for fluctuating glucose and O  supply in tumor cells.

F1000Res 2018 2;7:1177. Epub 2018 Aug 2.

Experimental Vascular Medicine, Amsterdam University Medical Centers, location AMC, Amsterdam, 1105 AZ, The Netherlands.

: Tumor cells often show altered metabolism which supports uncontrolled proliferation. A classic example is the Warburg effect: high glucose uptake and lactate production despite sufficient oxygen supply. Remarkably, tumor cells can transiently take up glucose even an order of magnitude faster when glucose is reintroduced after depletion. Read More

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http://dx.doi.org/10.12688/f1000research.15635.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352925PMC

Second-trimester presentation of midgut volvulus without intestinal malrotation.

Ultrasound Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, Charles University in Prague, Faculty of Medicine in Hradec Kralove, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.

Midgut volvulus, which is defined as a twist of small bowel loops or the proximal part of the colon around the superior mesenteric artery, represents a serious complication that typically manifests postnatally with a predominant occurrence during the first year of life. This article is protected by copyright. All rights reserved. Read More

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http://dx.doi.org/10.1002/uog.20239DOI Listing
February 2019
1 Read

Efficacy and safety of umbilical therapy with the traditional Chinese medicine formulation Lishui Xiaogu cataplasm for cirrhotic ascites: protocol for a randomized controlled trial.

Trials 2019 Feb 13;20(1):127. Epub 2019 Feb 13.

BUCM Institute of Liver Diseases, Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine, No. 5, Haiyuncang, Dongcheng District, Beijing, 100700, China.

Background: Ascites is one of the most common complications of cirrhosis. Umbilical therapy with traditional Chinese medicines has been increasingly prescribed to treat cirrhotic ascites. However, high-quality evidence from clinical trials supporting such application of traditional Chinese medicines remains limited. Read More

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http://dx.doi.org/10.1186/s13063-019-3221-yDOI Listing
February 2019

Liver volume index predicts the risk of esophageal variceal hemorrhage in cirrhotic patients on propranolol prophylaxis.

Korean J Intern Med 2019 Feb 18. Epub 2019 Feb 18.

Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Background/aims: Non-selective β-blockers (NSBBs) are used for primary prevention of esophageal variceal hemorrhage (VH) in patients with portal hypertension, but a significant number of patients develop VH while on NSBB therapy. In this study, we sought to determine whether liver volume can predict the risk of primary prophylaxis failure in cirrhotic patients on NSBB therapy.

Methods: A retrospective cohort of 309 patients on prophylactic propranolol was analyzed. Read More

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http://dx.doi.org/10.3904/kjim.2018.120DOI Listing
February 2019
1 Read

Repeated Treatment with Y-Microspheres in Intrahepatic Cholangiocarcinoma Relapsed After the First Radioembolization.

Cancer Biother Radiopharm 2019 Feb 13. Epub 2019 Feb 13.

1 Department of Nuclear Medicine, Santa Maria Goretti Hospital, Latina, Italy.

Background: The aim of this study was to evaluate the safety and efficacy of repeated administration of Y-microspheres in intrahepatic cholangiocarcinoma (ICC) relapsed after the first radioembolization (RE).

Methods: Nine patients with ICC relapsed after the first Y-RE were enrolled. Six patients presented recurrence in the right hepatic lobe, 3 in the left lobe. Read More

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http://dx.doi.org/10.1089/cbr.2018.2718DOI Listing
February 2019

Ultrastructural analysis of the Krebs-2 ascites cancer cells treated with extracellular double-stranded DNA preparation.

Ultrastruct Pathol 2019 Feb 13:1-10. Epub 2019 Feb 13.

a Institute of Cytology and Genetics , Siberian Branch of the Russian Academy of Sciences , Novosibirsk , Russia.

Electron-microscopic analysis of the ultrastructure of the Krebs-2 carcinoma ascites cells in the first 90 min immediately after their exposure to fragmented double-stranded DNA has been performed. Morphological attributes of the treated cancer cells indicate the induction in these cells of destructive processes of presumably apoptotic type. The predominance of dystrophic-destructive changes in cells after the addition of DNA is supposed to be a consequence of the disturbance in metabolic processes caused by the experimental action. Read More

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http://dx.doi.org/10.1080/01913123.2019.1575499DOI Listing
February 2019

Chylous Ascites due to Mantle Cell Lymphoma.

Eur J Case Rep Intern Med 2018 26;5(6):000871. Epub 2018 Jun 26.

Internal Medicine Department, Centro Hospitalar de Vila Nova de Gaia-Espinho, Portugal.

Chylous ascites is rare and results in accumulation of lymph in the abdominal cavity, due to several mechanisms. The ascitic liquid is milky because of the high concentration of triglycerides (>200 mg/dl). The higher incidence compared to the past is explained by increased survival of patients with cancer and more aggressive surgery. Read More

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http://dx.doi.org/10.12890/2018_000871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346885PMC

Constitutional Syndrome, Ascites and Duodenal Thickening Presenting as Groove Pancreatitis.

Eur J Case Rep Intern Med 2018 21;5(3):000789. Epub 2018 Mar 21.

Department of Internal Medicine, Hospital Francesc de Borja, Gandia, Valencia, Spain.

Groove pancreatitis (GP) is a very infrequent subtype of chronic pancreatitis affecting the pancreatic-duodenal junction. It usually manifests in middle-aged men with a history of chronic alcoholism, though it has also been described in women and in individuals who do not consume alcohol. Even though the underlying etiology is unclear, chronic alcohol consumption is known to increase the viscosity of the pancreatic juice and exacerbate the inflammatory process. Read More

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http://dx.doi.org/10.12890/2017_000789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346956PMC

Serum CA125 and ascites leptin level ratio predicts baseline clinical resistance to first-line platinum-based treatment and poor prognosis in patients with high grade serous ovarian cancer.

Am J Cancer Res 2019 1;9(1):160-170. Epub 2019 Jan 1.

Département de Microbiologie et Infectiologie, Département de Chirurgie, Faculté de Médecine, Université de Sherbrooke 3001, 12ième Avenue Nord, Sherbrooke, J1H 5N4, Canada.

About 20% of patients with high grade serous epithelial ovarian carcinoma (HGSOC) are intrinsically resistant to standard first-line platinum-based combination therapy. There is no marker yet available to identify these patients. In that context, all patients with HGSOC initially receive the same standard first-line platinum-based therapy, and those with intrinsically resistant diseases can only be identified retrospectively after they experienced early relapse to therapy. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356915PMC
January 2019

A Case of Eosinophilic Gastroenteritis Associated with Eosinophilic Ascites Diagnosed by Full-Thickness Biopsy of the Small Intestine.

Am J Case Rep 2019 Feb 13;20:189-193. Epub 2019 Feb 13.

College of Medicine, King Saud University, Riyadh, Saudi Arabia.

BACKGROUND Eosinophilic gastroenteritis is a rare disease, characterized by infiltrates of eosinophils in the intestinal mucosa, muscularis propria, and serosa. Eosinophilic gastroenteritis is due to Type 1 hypersensitivity and can be associated with other atopic diseases. The clinical course of eosinophilic gastroenteritis varies depending on the location, extent, and depth of eosinophilic infiltration of the gastrointestinal tract, which can make the diagnosis challenging. Read More

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http://dx.doi.org/10.12659/AJCR.913319DOI Listing
February 2019

Detection of free intraperitoneal tumour cells in peritoneal lavage fluid from patients with peritoneal metastasis before and after treatment with pressurised intraperitoneal aerosol chemotherapy (PIPAC).

J Clin Pathol 2019 Feb 12. Epub 2019 Feb 12.

Odense PIPAC Center, Odense University Hospital, Odense, Denmark.

Aims: In this study, we investigated whether free intraperitoneal tumour cells (FITC) were detectable in ascites or peritoneal lavage fluid (PLF) from patients with peritoneal metastasis (PM) before and after treatment with pressurised intraperitoneal aerosol chemotherapy (PIPAC).

Methods: Ascites or PLF retrieved at the first and third PIPAC procedures was analysed by conventional cytology, carcinoembryonic antigen (CEA) and total protein concentration, and quantitative reverse transcriptase PCR (qRT-PCR) for mRNA expression of CEA, epithelial cell adhesion molecule (EpCAM) and cancer antigen 125 (CA-125). Conventional cytology and qRT-PCR were also performed in a negative control group (benign PLF specimens and inflammatory ascites). Read More

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http://dx.doi.org/10.1136/jclinpath-2018-205683DOI Listing
February 2019

Outcomes of Combined Hernia Repair and Peritoneal Dialysis Catheter Placement: A NSQIP Analysis.

Am Surg 2018 Oct;84(10):1604-1607

Department of Surgery, Harbor-UCLA Medical Center, Torrance, California, USA.

Historically, hernias were repaired before peritoneal dialysis (PD) catheter placement to obviate hernia complications, or after PD catheter placement once hernias became symptomatic or complicated. The aim of this study was to evaluate the outcomes and safety of combined hernia repair and PD catheter placement (HPD) compared with PD catheter placement alone. Within the NSQIP databases (2005-2014), 4406 patients who underwent PD catheter placement alone and 330 patients who underwent HPD were identified. Read More

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October 2018

Roux-en-Y Gastric Bypass Reversal for Severe Malnutrition and Cirrhosis.

Obes Surg 2019 Feb 11. Epub 2019 Feb 11.

Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Digestive and Metabolic Surgery, Avicenne University Hospital, Centre intégré Nord Francilien de la prise en charge de l'Obésité (CINFO), Université Paris XIII-UFR SMBH « Léonard de Vinci », 125 route de Stalingrad, 93000, Bobigny, France.

Background: Severe post-operative malnutrition (SM) is a dreaded complication after gastric bypass often related to the short bowel syndrome consecutive limb length mismeasurement or intestinal resections. Patients with rapid weight loss or malnutrition can experience liver failure with cirrhosis and require liver transplantation (LT). Malnutrition can constitute a contraindication to LT since it negatively impacts on postoperative morbidity. Read More

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http://dx.doi.org/10.1007/s11695-019-03770-2DOI Listing
February 2019

Use of Dual X-ray Absorptiometry in men with advanced cirrhosis to predict sarcopenia-associated mortality risk.

Liver Int 2019 Feb 12. Epub 2019 Feb 12.

Austin Hospital Liver Transplant Unit, VIC, 3084.

Introduction: Reduced muscle area on CT scan is an independent predictor of mortality in cirrhosis. We examine for the first time the relationship between Dual Energy X-ray Absorptiometry (DEXA) lean mass parameters on outcomes in cirrhotic men awaiting liver transplantation.

Materials And Methods: We retrospectively reviewed DEXA scans performed during transplant assessment between 2001 and 2016. Read More

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http://dx.doi.org/10.1111/liv.14071DOI Listing
February 2019
2 Reads

Editorial: quality of life and mortality in cirrhosis and ascites.

Authors:
Ronan O'Carroll

Aliment Pharmacol Ther 2019 Mar;49(5):617-618

Psychology, University of Stirling, Stirling, UK.

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http://dx.doi.org/10.1111/apt.15122DOI Listing
March 2019
1 Read

Diagnostic value of acid phosphatases (ACP) in differentiating reactive mesothelial cells from cancer cells in the body fluid effusions.

J Thorac Dis 2018 Dec;10(12):6446-6451

Department of Pathology, The First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.

Background: The cytological diagnosis of a malignant epithelial tumor, i.e., a cancer cell in the body fluid effusions is usually made by cytomorphological examination alone; however, diagnostic challenges can occur when the cancer cells are rare or cytological atypia is minimal. Read More

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http://dx.doi.org/10.21037/jtd.2018.11.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344779PMC
December 2018
1 Read

The Prevalence of Asymptomatic Cervical and Lumbar Facet Arthropathy: A Computed Tomography Study.

Asian Spine J 2019 Feb 13. Epub 2019 Feb 13.

Department of Rehabilitation Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

Study Design: Case control study.

Purpose: To determine the prevalence and degree of asymptomatic cervical and lumbar facet joint arthritis. We retrospectively reviewed 500 computed tomography (CT) scans of cervical facet joints obtained from 50 subjects. Read More

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http://asianspinejournal.org/journal/view.php?doi=10.31616/a
Publisher Site
http://dx.doi.org/10.31616/asj.2018.0235DOI Listing
February 2019
1 Read

Neutrophil plays critical role during Edwardsiella piscicida immersion infection in zebrafish larvae.

Fish Shellfish Immunol 2019 Feb 8;87:565-572. Epub 2019 Feb 8.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China; Shanghai Engineering Research Center of Marine Cultured Animal Vaccines, Shanghai, 200237, China. Electronic address:

Edwardsiella piscicida is a facultative intracellular pathogen that causes hemorrhagic septicemia and haemolytic ascites disease in aquaculture fish. During bacterial infection, macrophages and neutrophils are the first line of host innate immune system. However, the role of neutrophils in response to E. Read More

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http://dx.doi.org/10.1016/j.fsi.2019.02.008DOI Listing
February 2019

Umbilical artery pulsatility index and half-peak systolic velocity deceleration time in fetuses with trisomy 21.

J Matern Fetal Neonatal Med 2019 Feb 10:1-7. Epub 2019 Feb 10.

b Fetal Imaging Unit , FETALMED-Maternal-Fetal Diagnostic Center , Santiago , Chile.

Objective: To analyze placental vascular resistance and the role of placental insufficiency in the etiology of reduced fetal growth in fetuses with trisomy 21 as determined by umbilical artery (UA) Doppler velocimetry.

Methods: Second- and third-trimester UA Doppler ultrasound studies were performed in fetuses with trisomy 21 at the time of clinically indicated obstetric ultrasound assessment. The UA pulsatility index (PI) and half-peak systolic velocity deceleration time (hPSV-DT) were measured and recorded. Read More

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http://dx.doi.org/10.1080/14767058.2019.1575357DOI Listing
February 2019
1 Read

Pre-Operative vs. Peri-Operative Nutrition Supplementation in Hepatic Resection for Cancer: A Systematic Review.

Nutr Cancer 2019 Feb 9:1-20. Epub 2019 Feb 9.

c Discipline of Surgery, School of Medicine , University of Sydney , Camperdown , NSW , Australia.

Despite improvements in safety of hepatic resection post-operative complications occur in up to a half of patients. A systematic review was undertaken to compare the effect of pre-operative and peri-operative nutritional supplementation on post-operative outcomes in patients undergoing hepatic resection for malignancy. Included studies were identified through a search of PubMed (1966 to November 2016), Embase (1947 to November 2016) and the Cochrane Library (1993 to November 2016). Read More

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http://dx.doi.org/10.1080/01635581.2018.1560479DOI Listing
February 2019

A case of pseudo-pseudo Meigs' syndrome.

Oxf Med Case Reports 2019 Jan 31;2019(2):omy136. Epub 2019 Jan 31.

Rheumatology Department, Royal Berkshire Hospital, UK.

Here we report a case of a patient with systemic lupus erythematosus presenting with pseudo-pseudo Meigs' syndrome (PPMS): a triad of pleural effusion, ascites and raised CA-125. There have only been nine other cases reported in the literature. To our knowledge, this is the first to have an oesophago-gastro-duodenoscopy and liver biopsy as part of the diagnostic work up. Read More

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http://dx.doi.org/10.1093/omcr/omy136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355105PMC
January 2019
1 Read

Collagen type IV remodeling gender-specifically predicts mortality in decompensated liver cirrhosis.

Liver Int 2019 Feb 9. Epub 2019 Feb 9.

Department of Medicine I, University of Bonn, Bonn, Germany.

Background: Remodeling of extracellular matrix (ECM) is crucial in progressive liver fibrosis. Collagen type III desposition has been shown in acute decompensation. ECM is compiled of deposition of various components. Read More

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http://dx.doi.org/10.1111/liv.14070DOI Listing
February 2019
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Bacterial peritonitis in a patient with malignant ascites caused by pancreatic carcinoma: Case report and review of literature.

J Infect Chemother 2019 Feb 6. Epub 2019 Feb 6.

Department of Infectious Diseases, The University of Tokyo Hospital, Tokyo, Japan.

Bacterial peritonitis, an infection of the ascitic fluid, can be classified etiologically as spontaneous or secondary bacterial peritonitis. The former is mainly caused by portal hypertension and its subsequent effects, whereas the latter is caused by the direct dissemination of bacteria into the peritoneal cavity. Previous reports have described some distinguishing features of these two entities. Read More

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http://dx.doi.org/10.1016/j.jiac.2019.01.007DOI Listing
February 2019
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Influence of proton pump inhibitors on microbiota in chronic liver disease patients.

Hepatol Int 2019 Feb 8. Epub 2019 Feb 8.

Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya, 466-8550, Japan.

Background: Current knowledge suggests that proton pump inhibitors (PPIs) are associated with an increased risk of hepatic encephalopathy (HE) and spontaneous bacterial peritonitis (SBP). These conditions and PPI use are related to gut microbiota. The aim of this study is to research the changes in gut microbiota caused by PPI in patients with chronic liver disease. Read More

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http://link.springer.com/10.1007/s12072-019-09932-9
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http://dx.doi.org/10.1007/s12072-019-09932-9DOI Listing
February 2019
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Sensitivity of a bedside reagent strip for the detection of spontaneous bacterial peritonitis in ED patients with ascites.

Am J Emerg Med 2019 Jan 25. Epub 2019 Jan 25.

Department of Emergency Medicine, Loma Linda University Medical Center, Loma Linda, CA, United States of America.

Study Objective: To determine the sensitivity of a highly sensitive bedside leukocyte esterase reagent strip (RS) for detection of spontaneous bacterial peritonitis (SBP) in emergency department (ED) ascites patients undergoing paracentesis.

Methods: We conducted a prospective, observational cohort study of ED ascites patients undergoing paracentesis at two academic facilities. Two practitioners, blinded to each other's results, did a bedside RS analysis of the peritoneal fluid in each patient and documented the RS reading at 3-min according to manufacturer-specified colorimetric strip reading as either "negative", "trace", "small", or "large". Read More

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http://dx.doi.org/10.1016/j.ajem.2019.01.044DOI Listing
January 2019
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Comprehensive Characterization of a Porcine Model of The "Small-for-Flow" Syndrome.

J Gastrointest Surg 2019 Feb 7. Epub 2019 Feb 7.

Transplant and Hepatobiliopancreatic Surgery Unit, Department of General and Digestive Surgery, Hospital General Universitario Gregorio Marañón - IiSGM, Madrid, Spain.

Introduction: The term "Small-for-Flow" reflects the pathogenetic relevance of hepatic hemodynamics for the "Small-For-Size" syndrome and posthepatectomy liver failure. We aimed to characterize a large-animal model for studying the "Small-for-Flow" syndrome.

Methods: We performed subtotal (90%) hepatectomies in 10 female MiniPigs using a simplified transection technique with a tourniquet. Read More

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http://dx.doi.org/10.1007/s11605-019-04130-2DOI Listing
February 2019
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Laparoscopic surgical repair of refractory chylous ascites after laparoscopic anterior resection.

Tech Coloproctol 2019 Feb 7. Epub 2019 Feb 7.

Department of Surgery, Chonnam National University Hwasun Hospital and Medical School, 322 Seoyang-ro Hwasun-eup, Hwasun-gun Jeonnam, Hwasun, 58128, South Korea.

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http://dx.doi.org/10.1007/s10151-019-01930-1DOI Listing
February 2019

Renal impairment is associated with increased risk of mortality in patients with cirrhosis: A retrospective cohort study.

Medicine (Baltimore) 2019 Feb;98(6):e14475

Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine.

Although renal impairment is a frequent complication in cirrhosis that is associated with a poor prognosis, little has been reported on the clinical significance of renal impairment in cirrhosis in Japan. This retrospective study assessed the impact of renal impairment on mortality in Japanese cirrhosis patients taking conventional diuretics.A total of 157 patients with cirrhosis receiving diuretic treatment were evaluated for the presence and status of renal impairment, defined as an increase in serum creatinine of ≥ 0. Read More

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http://dx.doi.org/10.1097/MD.0000000000014475DOI Listing
February 2019

Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.

JCI Insight 2019 Feb 7. Epub 2019 Feb 7.

Epithelial ovarian cancer (EOC) often presents with metastases and ascites. Granulocytic myeloid-derived suppressor cells are an immature population that impairs anti-tumor immunity. Since suppressive granulocytes in the ascites of patients with newly diagnosed EOC were morphologically mature, we hypothesized that PMN were rendered suppressive in the tumor microenvironment. Read More

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http://dx.doi.org/10.1172/jci.insight.122311DOI Listing
February 2019
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Outcomes of fertility-sparing surgery in ovarian juvenile granulosa cell tumor.

Int J Gynecol Cancer 2019 Feb 6. Epub 2019 Feb 6.

Department of Gynecology Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Objective: To analyze the clinical characteristics, diagnosis, and treatment of ovarian juvenile granulosa cell tumor.

Methods: The clinical and pathological data of six patients with ovarian juvenile granulosa cell tumor was collected.

Results: The mean age of disease onset was 20. Read More

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http://ijgc.bmj.com/lookup/doi/10.1136/ijgc-2018-000083
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http://dx.doi.org/10.1136/ijgc-2018-000083DOI Listing
February 2019
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[Refractory ascites caused by lymphatic flow disorder after stem cell transplantation for acute myeloid leukemia].

Rinsho Ketsueki 2019 ;60(1):12-16

Department of Hematology, Graduate School of Medicine, Osaka City University.

In allogeneic hematopoietic stem cell transplantation (HSCT), ascites may develop owing to several causes, including sinusoidal obstruction syndrome, infections, malignancies, and malnutrition. However, it is often difficult to determine its precise cause. Here, a 59-year-old male developed chylous ascites three months post allogeneic bone marrow transplantation for relapsed acute myeloid leukemia. Read More

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http://dx.doi.org/10.11406/rinketsu.60.12DOI Listing
January 2019
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Complication rates of percutaneous biliary drainage in the presence of ascites.

Abdom Radiol (NY) 2019 Feb 6. Epub 2019 Feb 6.

Department of Interventional Radiology, The Hospital of the University of Pennsylvania, Philadelphia, PA, 19104, USA.

Background: Ascites is a relative contraindication to percutaneous biliary drainage (PBD), but patients with biliary obstruction presenting with ascites may still undergo PBD insertion. We hypothesized that ascites increases the major complication rate of PBD.

Materials: PBDs placed between January 2005 and August 2016 were identified (n = 491). Read More

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http://dx.doi.org/10.1007/s00261-019-01916-5DOI Listing
February 2019

Enhanced anti-tumor activity of doxorubicin and simvastatin combination loaded nanoemulsion treatment against a Swiss albino mouse model of Ehrlich ascites carcinoma.

Clin Exp Pharmacol Physiol 2019 Feb 6. Epub 2019 Feb 6.

Health Information Technology Department, Jeddah Community College, King Abdulaziz University, P.O. Box- 80283, Jeddah-21589, Kingdom of Saudi Arabia.

Doxorubicin (DOX) is the most commonly used anticancer drug; however, it has limited use because prolonged administration may result in severe cardiotoxicity. Simvastatin (SIM), generally prescribed for hypercholesterolemia, has also shown salubrious results in the monotherapy or combinational drug therapy of different cancers in various models. Nanoparticle drug delivery systems are a novel way of improving therapeutics and also improve the absorption and specificity of drugs towards tumor cells. Read More

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http://dx.doi.org/10.1111/1440-1681.13071DOI Listing
February 2019
2 Reads