163,571 results match your criteria Arts & Health[Journal]


A state-of-the-art review on badminton lunge attributes.

Comput Biol Med 2019 Apr 6;108:213-222. Epub 2019 Apr 6.

School of Mechanical Engineering, Engineering Campus, Universiti Sains Malaysia, 14300, Nibong Tebal, Penang, Malaysia. Electronic address:

Good badminton lunge skills have been quantitatively described using biomechanical attributes at both static and dynamic phases. The measurement of badminton lunge attributes has often been complicated by various experimental protocols used. No review article has considered or critically reviewed the attributes that align with badminton lunge performance. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00104825193011
Publisher Site
http://dx.doi.org/10.1016/j.compbiomed.2019.04.003DOI Listing
April 2019
1 Read

A multi-scale data fusion framework for bone age assessment with convolutional neural networks.

Comput Biol Med 2019 Mar 19;108:161-173. Epub 2019 Mar 19.

Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada.

Bone age assessment (BAA) has various clinical applications such as diagnosis of endocrine disorders and prediction of final adult height for adolescents. Recent studies indicate that deep learning techniques have great potential in developing automated BAA methods with significant advantages over the conventional methods based on handcrafted features. In this paper, we propose a multi-scale data fusion framework for bone age assessment with X-ray images based on non-subsampled contourlet transform (NSCT) and convolutional neural networks (CNNs). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.compbiomed.2019.03.015DOI Listing

A novel end-to-end brain tumor segmentation method using improved fully convolutional networks.

Comput Biol Med 2019 Mar 18;108:150-160. Epub 2019 Mar 18.

School of Information Science and Technology, and Centers for Biomedical Engineering, University of Science and Technology of China, Hefei, AH 230027, China.

Accurate brain magnetic resonance imaging (MRI) tumor segmentation continues to be an active research topic in medical image analysis since it provides doctors with meaningful and reliable quantitative information in diagnosing and monitoring neurological diseases. Successful deep learning-based proposals have been designed, and most of them are built upon image patches. In this paper, a novel end-to-end brain tumor segmentation method is developed using an improved fully convolutional network by modifying the U-Net architecture. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00104825193008
Publisher Site
http://dx.doi.org/10.1016/j.compbiomed.2019.03.014DOI Listing
March 2019
2 Reads

Sources and Dynamics of Semivolatile Organic Compounds in a Single-Family Residence in Northern California.

Indoor Air 2019 Apr 20. Epub 2019 Apr 20.

Department of Environmental Science, Policy, and Management, University of California, Berkeley, USA.

Semivolatile organic compounds (SVOCs) emitted from building materials, consumer products, and occupant activities alter the composition of air in residences where people spend most of their time. Exposures to specific SVOCs potentially pose risks to human health. However, little is known about the chemical complexity, total burden, and dynamic behaviour of SVOCs in residential environments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ina.12561DOI Listing

A framework for space-efficient variable-order Markov models.

Bioinformatics 2019 Apr 20. Epub 2019 Apr 20.

CAPA, DTISI, Centre de Recherche sur l'Information Scientifique et Technique, Algiers, Algeria.

Motivation: Markov models with contexts of variable length are widely used in bioinformatics for representing sets of sequences with similar biological properties. When models contain many long contexts, existing implementations are either unable to handle genome-scale training datasets within typical memory budgets, or they are optimized for specific model variants and are thus inflexible.

Results: We provide practical, versatile representations of variable-order Markov models and of interpolated Markov models, that support a large number of context-selection criteria, scoring functions, probability smoothing methods, and interpolations, and that take up to four times less space than previous implementations based on the suffix array, regardless of the number and length of contexts, and up to ten times less space than previous trie-based representations, or more, while matching the size of related, state-of-the-art data structures from Natural Language Processing. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/bioinformatics/advance-article/doi/
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/btz268DOI Listing
April 2019
1 Read

The contribution of KSHV to mortality in hospitalized HIV-infected patients being investigated for tuberculosis in South Africa.

J Infect Dis 2019 Apr 20. Epub 2019 Apr 20.

Division of Medical Biochemistry and Structural Biology, Department of Integrative Biomedical Sciences, University of Cape Town, South Africa.

Background: Despite increasing numbers of human immunodeficiency virus (HIV)-infected South Africans receiving antiretroviral therapy (ART), tuberculosis remains the leading cause of mortality. Approximately 25% of patients treated for tuberculosis have microbiologically unconfirmed diagnoses. We assessed whether elevated Kaposi's sarcoma-associated Herpes Virus (KSHV) viral load (VL) contributes to mortality in hospitalized HIV-infected patients investigated for tuberculosis. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/jid/advance-article/doi/10.1093/inf
Publisher Site
http://dx.doi.org/10.1093/infdis/jiz180DOI Listing
April 2019
1 Read

Acquired Von Willebrand Syndrome (AVWS) in cardiovascular disease: a state of the art review for clinicians.

J Thromb Thrombolysis 2019 Apr 19. Epub 2019 Apr 19.

Stonehill Professor of Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, CVC 4th Floor, Room 4936, Cincinnati, 45267, OH, USA.

Von Willebrand Factor (vWF) is a large glycoprotein with a broad range of physiological and pathological functions in health and disease. While vWF is critical for normal hemostasis, vascular integrity and repair, quantitative and qualitative abnormalities in the molecule can predispose to serious bleeding and thrombosis. The heritable form of von Willebrand Disease was first described nearly a century ago, but more recently, recognition of an acquired condition known as acquired von Willebrand Syndrome (AVWF) has emerged in persons with hematological, endocrine and cardiovascular diseases, disorders and conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11239-019-01849-2DOI Listing

Cytotoxicity screening of supercritical fluid extracted seaweeds and phenylpropanoids.

Mol Biol Rep 2019 Apr 19. Epub 2019 Apr 19.

Department of Bioengineering, Faculty of Engineering, Ege University, 35100, Bornova, Izmir, Turkey.

Detached leaves of Posidonia oceanica and Zostera marina creating nuisance at the shores were extracted by means of supercritical CO enriched with a co-solvent, compared with that of soxhlet extraction. The extracts and their active compounds which are phenylpropanoids (chicoric, p-coumaric, rosmarinic, benzoic, ferulic and caffeic acids) were screened for cytotoxicity in cancer cell lines including human breast adenocarcinoma (MCF-7, MDA-MB-231, SK-BR-3), human colon adenocarcinoma (HT-29), human cervix adenocarcinoma (HeLa), human prostate adenocarcinoma (PC-3), Mus musculus neuroblastoma (Neuro 2A) cell lines and African green monkey kidney (VERO) as healthy cell line. Supercritical CO extracts proved to be more active than soxhlet counterparts. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11033-019-04812-9
Publisher Site
http://dx.doi.org/10.1007/s11033-019-04812-9DOI Listing
April 2019
1 Read

Epistemic burdens and the incentives of surrogate decision-makers.

Med Health Care Philos 2019 Apr 19. Epub 2019 Apr 19.

Faculty of Social Science, College of Integrative Sciences and Arts, Arizona State University Polytechnic Campus, Santa Catalina Hall, 250A, 7271 E Sonoran Arroyo Mall, Mesa, AZ, 85212, USA.

We aim to establish the following claim: other factors held constant, the relative weights of the epistemic burdens of competing treatment options serve to determine the options that patient surrogates pursue. Simply put, surrogates confront an incentive, ceteris paribus, to pursue treatment options with respect to which their knowledge is most adequate to the requirements of the case. Regardless of what the patient would choose, options that require more knowledge than the surrogate possesses (or is likely to learn) will either be neglected altogether or deeply discounted in the surrogate's incentive structure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11019-019-09899-2DOI Listing

Enhanced Permeation of Methotrexate via Loading into Ultra-permeable Niosomal Vesicles: Fabrication, Statistical Optimization, Ex Vivo Studies, and In Vivo Skin Deposition and Tolerability.

AAPS PharmSciTech 2019 Apr 19;20(5):171. Epub 2019 Apr 19.

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Ainy Street, Cairo, 11562, Egypt.

The aim of this study was to incorporate methotrexate (MTX) into ultra-permeable niosomal vesicles, containing cremophor RH40 as an edge activator (EA) and polyvinyl alcohol (PVA) as a stabilizer to enhance the drug permeation. Formulae were prepared by ethanol injection method following a Box-Behnken design in order to optimize the formulation variables (EA%, stabilizer %, and sonication time). To investigate the role of both cremophor RH40 and PVA, conventional MTX niosomes and MTX niosomes containing PVA only were fabricated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1208/s12249-019-1380-5DOI Listing

The effect of luteal GnRH antagonist on moderate and severe early ovarian hyperstimulation syndrome during in vitro fertilization treatment: a prospective cohort study.

Arch Gynecol Obstet 2019 Apr 19. Epub 2019 Apr 19.

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, 100034, People's Republic of China.

Purpose: Ovarian hyperstimulation syndrome (OHSS) is a serious complication of assisted reproductive technology (ART) treatment. However, there are limited data regarding the ability of the luteal GnRH antagonist cetrorelix to reduce the incidence of moderate and severe OHSS, and the mechanism remains unclear. Thus, we designed a study to assess the effectiveness of cetrorelix to prevent early moderate and severe OHSS in high-risk patients undergoing controlled ovarian stimulation for IVF/ICSI. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00404-019-05163-3
Publisher Site
http://dx.doi.org/10.1007/s00404-019-05163-3DOI Listing
April 2019
1 Read

Orthogonal joint sparse NMF for microarray data analysis.

J Math Biol 2019 Apr 19. Epub 2019 Apr 19.

Department of Mathematics, University of Bari Aldo Moro, via E. Orabona 4, 70125, Bari, Italy.

The 3D microarrays, generally known as gene-sample-time microarrays, couple the information on different time points collected by 2D microarrays that measure gene expression levels among different samples. Their analysis is useful in several biomedical applications, like monitoring dose or drug treatment responses of patients over time in pharmacogenomics studies. Many statistical and data analysis tools have been used to extract useful information. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00285-019-01355-2
Publisher Site
http://dx.doi.org/10.1007/s00285-019-01355-2DOI Listing
April 2019
1 Read

The dynamics of self-control: within-participant modeling of binary food choices and underlying decision processes as a function of restrained eating.

Psychol Res 2019 Apr 19. Epub 2019 Apr 19.

Department of Psychology, Centre for Cognitive Neuroscience, Paris-Lodron-University of Salzburg, Hellbrunner Straße 34, 5020, Salzburg, Austria.

Successful self-control during food choice might require inhibition of impulses to avoid indulging in tempting but calorie-dense foods, and this might particularly apply to individuals restraining their food intake. Adopting a novel within-participant modeling approach, we tested 62 females during a mouse-tracking based binary food choice task. Subsequent ratings of foods on palatability, healthiness, and calorie density were modeled as predictors for both decision outcome (choice) and decision process (measures of self-control conflict) while considering the moderating role of restrained eating. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00426-019-01185-3
Publisher Site
http://dx.doi.org/10.1007/s00426-019-01185-3DOI Listing
April 2019
1 Read

Data gaps and opportunities for comparative and conservation biology.

Proc Natl Acad Sci U S A 2019 Apr 19. Epub 2019 Apr 19.

Interdisciplinary Center on Population Dynamics, University of Southern Denmark, 5230 Odense M, Denmark;

Biodiversity loss is a major challenge. Over the past century, the average rate of vertebrate extinction has been about 100-fold higher than the estimated background rate and population declines continue to increase globally. Birth and death rates determine the pace of population increase or decline, thus driving the expansion or extinction of a species. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1816367116DOI Listing
April 2019
1 Read

Winning with the public, winning in court: advocacy lessons learnt from 85% pictorial health warning campaign in Thailand.

Tob Control 2019 Apr 19. Epub 2019 Apr 19.

Department of Communication Arts, Chulalongkorn University, Bangkok, Thailand.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/tobaccocontrol-2018-054754DOI Listing

Health of adults aged 22 to 35 years conceived by assisted reproductive technology.

Fertil Steril 2019 Apr 9. Epub 2019 Apr 9.

Hudson Institute of Medical Research, Clayton, Victoria, Australia; Monash IVF Group Pty Ltd, Richmond, Victoria, Australia; Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia.

Objective: To determine the health outcomes for adults aged 22-35 years old who were conceived via assisted reproduction technology (ART) compared with adults of the same age conceived without use of ART.

Design: Cohort study.

Setting: Not applicable. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00150282193024
Publisher Site
http://dx.doi.org/10.1016/j.fertnstert.2019.03.001DOI Listing
April 2019
1 Read

Consumer Neuroscience and Digital/Social Media Health/Social Cause Advertisement Effectiveness.

Behav Sci (Basel) 2019 Apr 18;9(4). Epub 2019 Apr 18.

Centre for Mental Health, Faculty of Health, Art and Design, Swinburne University of Technology, PO Box 218, Hawthorn, Australia.

This research investigated the use of consumer neuroscience to improve and determine the effectiveness of action/emotion-based public health and social cause (HSC) advertisements. Action-based advertisements ask individuals to 'do something' such as 'act', 'share', make a 'pledge' or complete a 'challenge' on behalf of a brand, such as doing 'something good, somewhere, for someone else'. Public health messages as noncommercial advertisements attempt to positively change behavioural intent or increase awareness. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/bs9040042DOI Listing

Characterization and Design Improvement of a Thickness-Shear Lead Zirconate Titanate Transducer for Low Frequency Ultrasonic Guided Wave Applications.

Sensors (Basel) 2019 Apr 18;19(8). Epub 2019 Apr 18.

Brunel University London, Uxbridge UB8 3PH, UK.

Thickness-shear transducers for guided wave testing have been used in industry for over two decades and much research has been conducted to improve the resolution and sensitivity. Due to a geometric feature of the current state-of-the art transducer, there is an out-of-plane component in the propagation direction of the fundamental shear horizontal mode which complicates the signal interpretation. In such case, complex signal processing techniques need to be used for mode discrimination to assess the structural health with higher precision. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/s19081848DOI Listing

Calibration of Off-the-Shelf Anisotropic Magnetoresistance Magnetometers.

Sensors (Basel) 2019 Apr 18;19(8). Epub 2019 Apr 18.

Institute for Geophysics und Extraterrestrial Physics, Technische Universität Braunschweig, 38106 Braunschweig, Germany.

Magnetometers based on the anisotropic magnetoresistive effect are used in many applications for orientation determination, by measuring the magnetic field of the Earth. As sensors of this type are commercial, off-the-shelf components, manufacturers provide limited information on their measurement performance. Therefore, we present a (to date) unprecedented comprehensive calibration study on three state-of-the-art digital anisotropic magnetoresistance magnetometers, to precisely determine various performance parameters and stability across different sensors of the same model. Read More

View Article

Download full-text PDF

Source
https://www.mdpi.com/1424-8220/19/8/1850
Publisher Site
http://dx.doi.org/10.3390/s19081850DOI Listing
April 2019
1 Read

Simultaneous Quantification of Five Sesquiterpene Components after Ultrasound Extraction in L. by an Accurate and Rapid UPLC⁻PDA Assay.

Molecules 2019 Apr 18;24(8). Epub 2019 Apr 18.

School of Traditional Chinese Medicine, Capital Medical University, No.10, Xitoutiao, You'anmenwai, Fengtai District, Beijing 100069, China.

: To develop an accurate and rapid ultra-performance liquid chromatography (UPLC) coupled with a photodiode array (PDA) method for the simultaneous determination of artemisinin (Art), arteannuin B (Art B), arteannuin C (Art C), dihydroartemisinic acid (DHAA) and artemisinic acid (AA) in L. : Chromatography separation was performed on an ACQUITY UPLC BEH C18 Column with isocratic elution; the mobile phase was 0.1% formic acid aqueous solution (A) and acetonitrile (B) (A:B = 40:60, /). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules24081530DOI Listing

Modern Transference of Domestic Cooking Skills.

Nutrients 2019 Apr 18;11(4). Epub 2019 Apr 18.

Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 5DL, UK.

As the primary source of learning cooking skills; it is vital to understand what mothers think about the transference of cooking skills to their children. The current analysis aimed to highlight mothers' perceptions of children's involvement and cooking practices within the home setting. Sixteen focus group discussions were conducted on the island of Ireland (Republic of Ireland and Northern Ireland [UK]) with 141 mothers aged 20-39 years old. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu11040870DOI Listing

Wuqinxi Qigong as an Alternative Exercise for Improving Risk Factors Associated with Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials.

Int J Environ Res Public Health 2019 Apr 18;16(8). Epub 2019 Apr 18.

College of Chinese Martial Arts, Guangzhou Sport University, Guangzhou 510500, China.

The improvement of living standards has led to increases in the prevalence of hypokinetic diseases. In particular, multifactorial complex diseases, such as metabolic syndrome, are becoming more prevalent. Currently, developing effective methods to combat or prevent metabolic syndrome is of critical public health importance. Read More

View Article

Download full-text PDF

Source
https://www.mdpi.com/1660-4601/16/8/1396
Publisher Site
http://dx.doi.org/10.3390/ijerph16081396DOI Listing
April 2019
1 Read

Document-level attention-based BiLSTM-CRF incorporating disease dictionary for disease named entity recognition.

Comput Biol Med 2019 Apr 7;108:122-132. Epub 2019 Apr 7.

Department of Computer Science, Guangdong University of Technology, Guangzhou, China. Electronic address:

Background: Disease named entity recognition (NER) plays an important role in biomedical research. There are a significant number of challenging issues to be addressed; among these, the identification of rare diseases and complex disease names and the problem of tagging inconsistency (i.e. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00104825193011
Publisher Site
http://dx.doi.org/10.1016/j.compbiomed.2019.04.002DOI Listing
April 2019
3 Reads

Development of an innovative technology to segment luminal borders of intravascular ultrasound image sequences in a fully automated manner.

Comput Biol Med 2019 Mar 14;108:111-121. Epub 2019 Mar 14.

Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, 2109, Australia; School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Perth, Australia.

Although intravascular ultrasound (IVUS) is the commonest intravascular imaging modality, it still is inefficient for clinical use as it requires laborious manual analysis. This study demonstrates the feasibility of a near real-time fully automated technology for accurate identification, detection, and quantification of luminal borders in intravascular images. This technology uses a combination of the novel approaches of a self-tuning engine, dynamic and static masking systems, radar-wise scan, and contour correction cycle method. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.compbiomed.2019.03.008DOI Listing
March 2019
1 Read

Corrigendum to "Adenosine role in brain functions: Pathophysiological influence on Parkinson's disease and other brain disorders" [Pharmacol. Rep. 70 (2018) 661-667].

Pharmacol Rep 2019 Apr 16;71(3):465. Epub 2019 Apr 16.

Department of Veterans Affairs, New Jersey Health Care System, East Orange, NJ, USA; School of Social Sciences and Psychology and Marcs Institute for Brain and Behaviour, Western Sydney University, Sydney, New South Wales, Australia; Department of Social Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pharep.2018.10.015DOI Listing
April 2019
1 Read

Connecting experts in the agricultural and meteorological sciences to advance knowledge of pest management in a changing climate.

Sci Total Environ 2019 Apr 10;673:694-698. Epub 2019 Apr 10.

Experimental Allergy Laboratory, Department of Dermatology, Medical University of Vienna, Vienna, Austria.

There has been considerable progress in elucidating the physical aspects of climate change that directly impact food, feed, and fiber production. However, these impact assessments rarely account for climate induced changes associated with biological pests. The lack of collaboration between the pest management and climate science disciplines could be contributing to the problem. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00489697193165
Publisher Site
http://dx.doi.org/10.1016/j.scitotenv.2019.04.126DOI Listing
April 2019
1 Read

Terrestrial organic matter increases zooplankton methylmercury accumulation in a brown-water boreal lake.

Sci Total Environ 2019 Mar 29;674:9-18. Epub 2019 Mar 29.

Department of Bioscience, University of Oslo, Blindernveien 31, 0371 Oslo, Norway. Electronic address:

Increases in terrestrial organic matter (tOM) transport from catchments to boreal lakes can affect methylmercury (MeHg) accumulation in aquatic biota both directly by increasing concentrations of aqueous MeHg, and indirectly through effects on MeHg bioavailability and on energy pathways in the lower food web. We carried out a detailed seasonal study of water chemistry, zooplankton diet, and MeHg accumulation in zooplankton in two lakes with contrasting tOM concentrations. Between-lake differences explained 51% of the variability in our water chemistry data, with no observed effect of season or sampling depth, contrary to our expectations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.scitotenv.2019.03.446DOI Listing

Worldwide Network for Blood and Marrow Transplantation (WBMT) recommendations for establishing a hematopoietic stem cell transplantation program in countries with limited resources (Part II): clinical, technical and socio-economic considerations.

Biol Blood Marrow Transplant 2019 Apr 16. Epub 2019 Apr 16.

Center for Hematopoietic Stem Cell Transplantation, Aichi Medical University Hospital, Nagakute; Department of Hematology and Medical Oncology, University Hospital, Leipzig, Germany.

The development of hematopoietic stem cell transplantation (HSCT) programs can face significant challenges in most developing countries because such endeavors must compete with other government health care priorities, including the delivery of basic services. While this is may be a limiting factor, these countries should prioritize development of the needed expertise to offer state of the art treatments including transplantation, by providing financial, technological, legal, ethical and other needed support. This would prove beneficial in providing successful programs customized to the needs of their population, and potentially provide long-term cost-savings by circumventing the need for their citizens to seek care abroad. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2019.04.012DOI Listing

A Graph-based Approach for Characterizing Resident and Nurse Handoff Conversations.

J Biomed Inform 2019 Apr 16:103178. Epub 2019 Apr 16.

Department of Anesthesiology & Institute for Informatics, School of Medicine, Washington University in St Louis, St. Louis, MO.

Prior research has used a variety of qualitative and quantitative approaches for studying handoff communication. Due to the dynamic and interactive nature of handoffs, characterizing the structure and content of these conversations is challenging. In this paper, we use a graph-based approach to characterize handoff communication as a conversation network. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15320464193009
Publisher Site
http://dx.doi.org/10.1016/j.jbi.2019.103178DOI Listing
April 2019
1 Read

Sweet cognition: The differential effects of glucose consumption on attentional food bias in individuals of lean and obese status.

Physiol Behav 2019 Apr 16. Epub 2019 Apr 16.

Center for Health and Community, Department of Psychiatry, UCSF, United States; Department of Medicine, Division of Cardiology, UCSF, United States. Electronic address:

In general, glucose consumption improves cognitive performance; however, it is unknown whether glucose specifically enhances attentional food bias, and how this process may vary by BMI status. We hypothesized that glucose consumption would increase attentional food bias among individuals of obese BMI status more so than among individuals of lean BMI status. Participants (N = 35) completed the n-back, a working memory task modified to assess attentional food bias (ATT-Food), under fasting and glucose challenge conditions. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00319384183094
Publisher Site
http://dx.doi.org/10.1016/j.physbeh.2019.04.014DOI Listing
April 2019
1 Read

The Upper Hand of the Otu Amyloid Fibers: Increasing Enzymatic Activity and Prolonging Lifespan.

Mol Cell 2019 Apr;74(2):225-226

Hubrecht Institute of the Royal Netherlands Academy of Arts and Sciences & University Medical Center Utrecht, Utrecht, the Netherlands; Department of Biomedical Science of Cells and Systems, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:

The formation of amyloid fibers is usually associated with aging and neurodegeneration. In this issue of Molecular Cell, Ji et al. (2019) demonstrate that the deubiquitinase Otu coalesces into amyloid-like fibers to enhance its activity and ensure its optimum biological function. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2019.03.038DOI Listing

A Sustainable Self-reproducing Liposome Consisting of a Synthetic Phospholipid.

Chem Phys Lipids 2019 Apr 16. Epub 2019 Apr 16.

Department of Chemistry, Faculty of Science, Kanagawa University, Tsuchiya, Hiratsuka, Kanagawa, 259-1293, Japan. Electronic address:

A novel phosphoric membrane lipid (phospholipid) bearing an oleyl group as one of the hydrophobic chains formed a liposome with a thin lamella in water. Since the anionic membrane of pre-existing liposomes acted as a catalytic surface in phosphate buffer, membrane lipids could be generated from their precursor in an autocatalytic manner without the inclusion of catalytic amphiphiles in the liposome. The morphological changes of this anionic liposome were monitored both by flow cytometry and optical microscopy, and it was found that the liposomes deformed into a budding shape, followed by division, after the addition of a membrane precursor. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00093084183026
Publisher Site
http://dx.doi.org/10.1016/j.chemphyslip.2019.04.007DOI Listing
April 2019
1 Read

Effect of HIV-exposure and timing of anti-retroviral treatment on immunogenicity of trivalent live-attenuated polio vaccine in infants.

PLoS One 2019 19;14(4):e0215079. Epub 2019 Apr 19.

South African Medical Research Council, Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.

Introduction: The prevalence of HIV infection in South African pregnant women has been approximately 30% over the past decade; however, there has been a steady decline in mother-to-child transmission of HIV from 8% in 2008 to <2% in 2015. We evaluated the immunogenicity of live-attenuated trivalent oral polio vaccine (OPV) following the primary vaccination series (doses at birth, 6, 10 and 14 weeks of age) in HIV-exposed uninfected (HEU), HIV-infected infants initiated on early anti-retroviral treatment (HIV+/ART+), HIV-infected infants on deferred ART (HIV+/ART-) and HIV-unexposed infants (HU) as the referent group.

Methods: Serum polio neutralization antibody titres were evaluated to serotype-1, serotype-2 and serotype-3 at 6, 10 and 18 weeks of age. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215079PLOS

Sero-prevalence of Hepatitis B and C viral co-infections among HIV-1 infected ART-naïve individuals in Kumasi, Ghana.

PLoS One 2019 19;14(4):e0215377. Epub 2019 Apr 19.

Department of Clinical Microbiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Background: The study assessed the hepatitis B virus (HBV) and hepatitis C virus (HCV) co-infection paradigm among the human immunodeficiency virus (HIV) infected patients attending a tertiary hospital in Ghana. Also, the immunological and virological characterisation of these viruses, prior to antiretroviral therapy (ART) initiation was investigated.

Method: A total of 400 HIV infected (HIV type-1) treatment naïve subjects ≥18 years were enrolled and tested for HBsAg and anti-HCV. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215377PLOS

A fast two-stage active contour model for intensity inhomogeneous image segmentation.

PLoS One 2019 19;14(4):e0214851. Epub 2019 Apr 19.

Department of Applied Mathematics, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, PR China.

This paper presents a fast two-stage image segmentation method for intensity inhomogeneous image using an energy function based on a local region-based active contour model with exponential family. In the first stage, we preliminary segment the down-sampled images by the local correntropy-based K-means clustering model with exponential family, which can fast obtain a coarse result with low computational complexity. Subsequently, by taking the up-sampled contour of the first stage as initialization, we precisely segment the original images by the improved local correntropy-based K-means clustering model with exponential family in the second stage. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214851PLOS
April 2019
1 Read

Clinically Significant Drug-Drug Interaction in a Large Antiretroviral Treatment Centre in Lagos, Nigeria.

J Popul Ther Clin Pharmacol 2019 Jan 22;26(1):e1-e19. Epub 2019 Jan 22.

University of Lagos.

   Background: An important cause of treatment failure to antiretroviral therapy (ART) is the potential interaction between the antiretroviral (ARV) drugs and co-prescribed drugs used concomitantly for the treatment of opportunistic infections and co-morbid ailments in HIV-infected patients. Objectives: The study evaluated potential clinically significant drug interactions (CSDIs) occurring between recommended ART regimens and their co-prescribed non-antiretroviral drugs (CPD) Method: This study was carried out in a large HIV treatment centre (APIN clinic) in a Nigerian teaching hospital, in Lagos Nigeria, caring for over 20,000 registered patients. Electronic Medical Records (EMR) of 500 patients  who received treatment between 2005 and 2015, were selected using systematic random sampling, reviewed retrospectively, and evaluated for potential CSDIs using Liverpool HIV Pharmacology Database and other similar databases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.22374/1710-6222.26.1.1DOI Listing
January 2019

Transmitted HIV-1 drug resistance in a treatment naïve cohort of recently infected individuals from Chennai, India.

AIDS Res Hum Retroviruses 2019 Apr 19. Epub 2019 Apr 19.

National Institute for Research in Tuberculosis, HIV/AIDS, Chennai, Tamil Nadu, India ;

A cross sectional study was undertaken to examine the prevalence and pattern of HIV drug resistance mutations among recently HIV-1 infected and antiretroviral therapy-naïve individuals from Chennai, South India. The HIV-1 Pol gene encompassing the Protease and Reverse Transcriptase (RT) regions were analysed from 53 ART -naïve HIV-1 infected individuals using an in-house method for identifying drug resistance mutations by genotyping. The overall prevalence of transmitted drug resistance (TDR) was found to be 11. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/AID.2019.0022DOI Listing

Neuroprotective Effects of Zafirlukast, Piracetam and Their Combination on L-Methionine-Induced Vascular Dementia in Rats.

Fundam Clin Pharmacol 2019 Apr 18. Epub 2019 Apr 18.

Pharmacology Department, October University for Modern Science and Arts, 11787, 6, October City, Egypt.

Vascular dementia is considered a vascular cognitive impairment disease caused by neuronal degeneration in the brain. Several studies have supported the hypothesis that oxidative stress and endothelial dysfunction are the main pathogenic factors in vascular dementia. This current study aims to determine the possible neuroprotective effects of zafirlukast, piracetam and the combination of piracetam and zafirlukast on L-methionine-induced vascular dementia in rats. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/fcp.12473DOI Listing

Genome-wide expression profiling-based copy number variations and colorectal cancer risk in Chinese.

Mol Carcinog 2019 Apr 18. Epub 2019 Apr 18.

Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Genetic factors play important roles in colorectal carcinogenesis. This study was aimed to evaluate the effects of gene expression-related copy number variations (CNVs) on the risk of colorectal cancer in Chinese. Expression Quantitative Trait Locus (eQTL) mapping was conducted to explore the most regulatable gene expressions by CNVs among the whole genome based on publicly available data. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mc.23015DOI Listing
April 2019
2 Reads

Biochar/struvite composite as a novel potential material for slow release of N and P.

Environ Sci Pollut Res Int 2019 Apr 18. Epub 2019 Apr 18.

School of Earth Sciences and Resources, China University of Geosciences, Beijing, 100083, People's Republic of China.

For soil and environmental remediation, biochar/struvite composites are prepared by the crystallization-adsorption method. The recovery rates of N, P, and Mg in the solution increase to 99.02%, 97. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11356-019-04458-xDOI Listing

An acute increase in water temperature can increase free amino acid concentrations in the blood, brain, liver, and muscle in goldfish (Carassius auratus).

Fish Physiol Biochem 2019 Apr 17. Epub 2019 Apr 17.

Laboratory of Stress Physiology and Metabolism, Faculty of Arts and Science, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, 819-0395, Japan.

Water temperature directly affects the body temperature in fish, so increasing water temperatures in oceans and rivers will lead to increases in fish body temperatures. Whilst a range of responses of fish to increases in water temperature have been measured, amino acid metabolism in a fish under high water temperature (HT) conditions has not been investigated. The aim of this study was to determine the effects of an acute increase in water temperature on oxygen consumption, plasma cortisol concentrations, and free amino acid concentrations in plasma and several tissues in goldfish (Carassius auratus). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10695-019-00642-5DOI Listing

Effect of different phosphorus concentrations on biodiesel production from Isochrysis zhangjiangensis under nitrogen sufficiency or deprivation condition.

Appl Microbiol Biotechnol 2019 Apr 18. Epub 2019 Apr 18.

Fujian Provincial Key Laboratory of Soil Environmental Health and Regulation, College of Resources and Environment, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian, China.

The effects of two nitrogen (N) concentrations combining with three phosphorus (P) concentrations on Isochrysis zhangjiangensis growth and formation of fatty acid (FA) were investigated in this study. Biomass concentration, mass fraction, and productivity of FA in I. zhangjiangensis were low in N-deprived media. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-019-09814-yDOI Listing

Reviving the lost art of scleral buckling surgery for rhegmatogenous retinal detachment: evaluation of risk factors of detachments, poor physiological outcomes, and perspective from a developing country.

Ther Adv Ophthalmol 2019 Jan-Dec;11:2515841419838662. Epub 2019 Apr 7.

Lumbini Eye Institute, Lumbini, Nepal.

Purpose: To evaluate the primary anatomic and physiological success of scleral buckling surgery for rhegmatogenous retinal detachment and factors influencing its outcomes.

Methods: This is a prospective analytical study of 92 eyes that underwent scleral buckling at the Lumbini Eye Institute and Research Center, in Lumbini, Nepal. Parameters evaluated which could influence the outcome of the surgery included the lens status, duration of symptoms, locations of breaks, the extent of retinal detachment, and preoperative proliferative vitreoretinopathy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2515841419838662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454650PMC
April 2019
1 Read

Urine salts elucidate Early Neolithic animal management at Aşıklı Höyük, Turkey.

Sci Adv 2019 Apr 17;5(4):eaaw0038. Epub 2019 Apr 17.

Department of Prehistory, Istanbul University, Istanbul 34134, Turkey.

The process of sheep and goat (caprine) domestication began by 9000 to 8000 BCE in Southwest Asia. The early Neolithic site at Aşıklı Höyük in central Turkey preserves early archaeological evidence of this transformation, such as culling by age and sex and use of enclosures inside the settlement. People's strategies for managing caprines evolved at this site over a period of 1000 years, but changes in the scale of the practices are difficult to measure. Read More

View Article

Download full-text PDF

Source
http://advances.sciencemag.org/lookup/doi/10.1126/sciadv.aaw
Publisher Site
http://dx.doi.org/10.1126/sciadv.aaw0038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469938PMC
April 2019
5 Reads

Automatic skin lesion segmentation by coupling deep fully convolutional networks and shallow network with textons.

J Med Imaging (Bellingham) 2019 Apr 15;6(2):024001. Epub 2019 Apr 15.

University of Lincoln, Laboratory of Vision Engineering, School of Computer Science, Lincoln, United Kingdom.

Segmentation of skin lesions is an important step in computer-aided diagnosis of melanoma; it is also a very challenging task due to fuzzy lesion boundaries and heterogeneous lesion textures. We present a fully automatic method for skin lesion segmentation based on deep fully convolutional networks (FCNs). We investigate a shallow encoding network to model clinically valuable prior knowledge, in which spatial filters simulating simple cell receptive fields function in the primary visual cortex (V1) is considered. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1117/1.JMI.6.2.024001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462764PMC
April 2019
1 Read

Prevalence of Cognitive Impairment and Its Predictors among HIV/AIDS Patients on Antiretroviral Therapy in Jimma University Medical Center, Southwest Ethiopia.

Psychiatry J 2019 13;2019:8306823. Epub 2019 Mar 13.

Department of Biomedical Sciences, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.

Background: Cognitive impairment among human immunodeficiency virus (HIV) infected patients can lead to treatment nonadherence, faster progression of the illness, disability, and bed ridden state if we fail to detect it early. However, there is scarcity of previous published studies in Ethiopia on the assessment of cognitive impairment among HIV-positive patients. Hence, this study aimed to determine the prevalence and associated factors of cognitive impairment among HIV-positive patients receiving antiretroviral therapy (ART) at Jimma University Medical Center, Ethiopia. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/psychiatry/2019/8306823/
Publisher Site
http://dx.doi.org/10.1155/2019/8306823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436374PMC
March 2019
1 Read

Fed-Batch Cultivations of Under Multiple Nutrient-Limited Growth Conditions on Syngas as a Novel Option to Produce Poly(3-Hydroxybutyrate) (PHB).

Front Bioeng Biotechnol 2019 2;7:59. Epub 2019 Apr 2.

Institute of Life Technologies, University of Applied Sciences and Arts Western Switzerland (HES-SO Valais-Wallis), Sion, Switzerland.

Syngas from gasified organic waste materials is a promising feedstock for the biotechnological synthesis of the bioplastic poly([]-3-hydroxybutyrate) (PHB) with . In a first approach, growth studies were carried out with this strain in gas-tight serum vials. When syngas (40% CO, 40% H, 10% CO, and 10% N v/v) was diluted with N to 60%, a 4-fold higher biomass production was detected compared to samples grown on 100% syngas, thus indicating a growth inhibitory effect. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fbioe.2019.00059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454858PMC

Rare-Earth Orthophosphates From Atomistic Simulations.

Front Chem 2019 3;7:197. Epub 2019 Apr 3.

Forschungszentrum Jülich GmbH, Institute of Energy and Climate Research - IEK-6: Nuclear Waste Management and Reactor Safety, Jülich, Germany.

Lanthanide phosphates () are considered as a potential nuclear waste form for immobilization of Pu and minor actinides (Np, Am, and Cm). In that respect, in the recent years we have applied advanced atomistic simulation methods to investigate various properties of these materials on the atomic scale. In particular, we computed several structural, thermochemical, thermodynamic and radiation damage related parameters. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fchem.2019.00197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456693PMC

Competence in and Close Commensal Relatives: Mechanisms and Implications.

Front Cell Infect Microbiol 2019 3;9:94. Epub 2019 Apr 3.

Faculty of Dentistry, Institute of Oral Biology, University of Oslo, Oslo, Norway.

The mitis group of streptococci comprises species that are common colonizers of the naso-oral-pharyngeal tract of humans. and are close relatives and share ~60-80% of orthologous genes, but still present striking differences in pathogenic potential toward the human host. has long been recognized as a reservoir of antibiotic resistance genes for , as well as a source for capsule polysaccharide variation, leading to resistance and vaccine escape. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcimb.2019.00094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456647PMC

Flax ( L.) Fibers for Composite Reinforcement: Exploring the Link Between Plant Growth, Cell Walls Development, and Fiber Properties.

Front Plant Sci 2019 3;10:411. Epub 2019 Apr 3.

IRDL, UMR CNRS 6027, Université de Bretagne Sud, Lorient, France.

Due to the combination of high mechanical performances and plant-based origin, flax fibers are interesting reinforcement for environmentally friendly composite materials. An increasing amount of research articles and reviews focuses on the processing and properties of flax-based products, without taking into account the original key role of flax fibers, namely, reinforcement elements of the flax stem ( L.). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fpls.2019.00411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456768PMC