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    5549 results match your criteria Artificial Organs[Journal]

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    Experimental Investigation of Left Ventricular Flow Patterns After Percutaneous Edge-to-Edge Mitral Valve Repair.
    Artif Organs 2017 Nov 23. Epub 2017 Nov 23.
    Department of Mechanical Engineering, University of Ottawa, Ottawa, Ontario, Canada.
    Mitral valve percutaneous edge-to-edge repair (PEtER) is a viable solution in high-risk patients with severe symptomatic mitral regurgitation. However, the generated double-orifice configuration poses challenges for the evaluation of the hemodynamic performance of the mitral valve and may alter flow patterns in the left ventricle (LV) during diastole. This in vitro study aims to evaluate the hemodynamic modifications following a simulated PEtER. Read More

    Retrieval of Adult Patients on Extracorporeal Membrane Oxygenation by an Intensive Care Physician Model.
    Artif Organs 2017 Nov 19. Epub 2017 Nov 19.
    The Intensive Care Unit, The Alfred Hospital, Melbourne, Victoria, Australia.
    The optimal staffing model during the inter-hospital transfer of patients on extracorporeal membrane oxygenation (ECMO) is not known. We report the complications and outcomes of patients who were commenced on ECMO at a referring hospital by intensive care physicians and compare these findings with patients who had ECMO established at an ECMO center in Australia. This was a single center, retrospective observational study based on a prospectively collected ECMO database from Melbourne, Australia. Read More

    Artificial Walking Technologies to Improve Gait in Cerebral Palsy: Multichannel Neuromuscular Stimulation.
    Artif Organs 2017 Nov;41(11):E233-E239
    Thayer School of Engineering, Hanover, NH, USA.
    Cerebral palsy (CP) is the most common childhood motor disability and often results in debilitating walking abnormalities, such as flexed-knee and stiff-knee gait. Current medical and surgical treatments are only partially effective in improving gait abnormalities and may cause significant muscle weakness. However, emerging artificial walking technologies, such as step-initiated, multichannel neuromuscular electrical stimulation (NMES), can substantially improve gait patterns and promote muscle strength in children with spastic CP. Read More

    Brain-Computer Interfaces With Multi-Sensory Feedback for Stroke Rehabilitation: A Case Study.
    Artif Organs 2017 Nov;41(11):E178-E184
    Guger Technologies OG, Graz, Austria.
    Conventional therapies do not provide paralyzed patients with closed-loop sensorimotor integration for motor rehabilitation. This work presents the recoveriX system, a hardware and software platform that combines a motor imagery (MI)-based brain-computer interface (BCI), functional electrical stimulation (FES), and visual feedback technologies for a complete sensorimotor closed-loop therapy system for poststroke rehabilitation. The proposed system was tested on two chronic stroke patients in a clinical environment. Read More

    Effects of Sensitive Electrical Stimulation-Based Somatosensory Cueing in Parkinson's Disease Gait and Freezing of Gait Assessment.
    Artif Organs 2017 Nov;41(11):E222-E232
    Service de Neurologie, CHU Montpellier Hospital, Montpellier, France.
    This study aims to investigate the effect of a somatosensory cueing on gait disorders in subjects with Parkinson's disease (PD). After having performed stepping in place and timed up and go assessing tasks, 13 participants with PD were equipped with an electrical stimulator and an inertial measurement unit (IMU) located under the lateral malleolus on the sagittal plane. Electrodes were positioned under the arch of the foot and electrical stimulation (ES) parameters (five 500 µs/phase charge-balanced biphasic pulses delivered at 200 Hz, repeated four times at 10 Hz) adjusted to deliver a sensitive signal. Read More

    Cadence Tracking and Disturbance Rejection in Functional Electrical Stimulation Cycling for Paraplegic Subjects: A Case Study.
    Artif Organs 2017 Nov;41(11):E185-E195
    NTAAI - Núcleo de Tecnologia Assistiva, Acessibilidade e Inovação and Programa de Pós-Graduação em Ciências e Tecnologias em Saúde, Faculdade de Ceilândia, Universidade de Brasília, Brasília, Brazil.
    Functional electrical stimulation cycling has been proposed as an assistive technology with numerous health and fitness benefits for people with spinal cord injury, such as improvement in cardiovascular function, increase in muscular mass, and reduction of bone mass loss. However, some limitations, for example, lack of optimal control strategies that would delay fatigue, may still prevent this technology from achieving its full potential. In this work, we performed experiments on a person with complete spinal cord injury using a stationary tadpole trike when both cadence tracking and disturbance rejection were evaluated. Read More

    In Vivo Validation of a Less Invasive Gastrostimulator.
    Artif Organs 2017 Nov;41(11):E213-E221
    Bio, Electro and Mechanical Systems Department, Université Libre de Bruxelles, Brussels, Belgium.
    Gastrointestinal stimulator implants have recently shown promising results in helping obese patients lose weight. However, to place the implant, the patient currently needs to undergo an invasive surgical procedure. We report a less invasive procedure to stimulate the stomach with a gastrostimulator. Read More

    Temporal and Spatial Variability of Surface Motor Activation Zones in Hemiplegic Patients During Functional Electrical Stimulation Therapy Sessions.
    Artif Organs 2017 Nov;41(11):E166-E177
    Tecnalia Research & Innovation - Health Division, San Sebastián, Spain.
    The goal of this study was to investigate surface motor activation zones and their temporal variability using an advanced multi-pad functional electrical stimulation system. With this system motor responses are elicited through concurrent activation of electrode matrix pads collectively termed "virtual electrodes" (VEs) with appropriate stimulation parameters. We observed VEs used to produce selective wrist, finger, and thumb extension movements in 20 therapy sessions of 12 hemiplegic stroke patients. Read More

    A Pseudo-One Compartment Model of Phosphorus Kinetics During Hemodialysis: Further Supporting Evidence.
    Artif Organs 2017 Nov 26;41(11):1043-1048. Epub 2017 May 26.
    Baxter Healthcare Corporation, Deerfield, IL.
    A pseudo-one compartment model has been proposed to describe phosphorus kinetics during hemodialysis and the immediate post-dialysis period. This model assumes that phosphorus mobilization from tissues is proportional to the difference between the pre-dialysis serum concentration (a constant) and the instantaneous serum concentration. The current study is exploratory and evaluated the ability of a pseudo-one compartment model to describe the kinetics of phosphorus during two short hemodialysis treatments separated by a 60-min inter-treatment period without dialysis; the latter is the post-dialysis rebound period for the first short hemodialysis treatment. Read More

    Development of Functional Electrical Stimulation Rowing: The Rowstim Series.
    Artif Organs 2017 Nov;41(11):E203-E212
    MS Society of Alberta, Alberta, Canada.
    Potentially, functional electrical stimulation (FES)-assisted exercise may have an important therapeutic role in reducing comorbidities associated with spinal cord injury (SCI). Here, we present an overview of these secondary life-threatening conditions, discuss the rationale behind the development of a hybrid exercise called FES rowing, and describe our experience in developing FES rowing technology. FES rowing and sculling are unique forms of adaptive rowing for those with SCI. Read More

    Step Ergometer Training Augmented With Functional Electrical Stimulation in Individuals With Chronic Spinal Cord Injury: A Feasibility Study.
    Artif Organs 2017 Nov;41(11):E196-E202
    Craig Hospital, Denver, CO, USA.
    Spinal cord injury (SCI) often results in loss of upright mobility and independence subsequently challenging rehabilitation practitioners for meaningful intervention strategies. The objective of this study was to evaluate the feasibility and potential impact on walking function of the stimulation and ergometer training protocol (STEP) in chronic SCI. Fourteen individuals with a chronic motor incomplete SCI (>1-year post injury) were enrolled in the study. Read More

    Timing of Intra-Aortic Balloon Pump Placement Before Off-Pump Coronary Artery Bypass Grafting and Clinical Outcomes.
    Artif Organs 2017 Nov 8. Epub 2017 Nov 8.
    Extracorporeal Circulation Department, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
    We aimed to evaluate the timing of preoperative intra-aortic balloon pump (IABP) placement and outcomes in patients undergoing off-pump coronary artery bypass grafting (OPCAB). Patients with prophylactic IABP placement before OPCAB presenting between January 1, 2010 and December 31, 2013 were included. Patients were categorized into two groups based on the timing of preoperative IABP placement: less than 2 h (Group A, n = 223) and more than 2 h (Group B, n = 94). Read More

    Development of a Pediatric Cardiac Mechanical Support Program.
    Artif Organs 2017 Nov 3. Epub 2017 Nov 3.
    Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
    The development of a pediatric cardiac support program is a complex, multidisciplinary project. This study describes the University of Iowa Congenital Heart Program's experience from its inception to the present. In, we examine those specific factors that have led to substantial improvements in the program, additionally identifying where further gains can be made. Read More

    Standardized Comparison of Selected Physiological Controllers for Rotary Blood Pumps: In Vitro Study.
    Artif Organs 2017 Nov 2. Epub 2017 Nov 2.
    Department of Mechanical and Process Engineering, Product Development Group Zurich, ETH Zurich, Zurich, Switzerland.
    Various physiological controllers for left ventricular assist devices (LVADs) have been developed to prevent flow conditions that may lead to left ventricular (LV) suction and overload. In the current study, we selected and implemented six of the most promising physiological controllers presented in literature. We tuned the controllers for the same objectives by using the loop-shaping method from control theory. Read More

    New Technology Mimics Physiologic Pulsatile Flow During Cardiopulmonary Bypass.
    Artif Organs 2017 Oct 27. Epub 2017 Oct 27.
    Department of Biomedical Engineering, Lerner Research Institute, Cleveland, OH.
    The VentriFlo True Pulse Pump (Design Mentor, Inc., Pelham, NH, USA) is the first blood pump designed to mimic human arterial waveforms in a standard oxygenation circuit. Our aim was to demonstrate the feasibility and safety of this pump in preparation for future studies to determine possible clinical advantages. Read More

    A New Pressure Guided Management Tool for Epidural Space Detection: Feasibility Assessment on a Simulator.
    Artif Organs 2017 Oct 25. Epub 2017 Oct 25.
    Unit of Measurements and Biomedical Instrumentation, Università Campus Bio-Medico di Roma, Rome, Italy.
    The detection of epidural space is usually performed by the technique of loss of resistance (LOR) without technological support, although there are few commercial options. We sought to design and develop a new noninvasive system able to detect the LOR without any changes to the conventional procedure. It allows detecting the LOR by a custom made algorithm. Read More

    EMG-Based Estimation of Limb Movement Using Deep Learning With Recurrent Convolutional Neural Networks.
    Artif Organs 2017 Oct 25. Epub 2017 Oct 25.
    School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
    A novel model based on deep learning is proposed to estimate kinematic information for myoelectric control from multi-channel electromyogram (EMG) signals. The neural information of limb movement is embedded in EMG signals that are influenced by all kinds of factors. In order to overcome the negative effects of variability in signals, the proposed model employs the deep architecture combining convolutional neural networks (CNNs) and recurrent neural networks (RNNs). Read More

    Third Generation Ventricular Assist Device: Mid-Term Outcomes of the HeartWare HVAD in Pediatric Patients.
    Artif Organs 2017 Oct 15. Epub 2017 Oct 15.
    Department of Pediatric Cardiology, Turkey Yuksek Ihtisas Hospital, Ankara, Turkey.
    The HeartWare HVAD is a small, third generation continuous flow pump that is intracorporeally placed for support of a failing ventricle in adult patients. This device is small in size when compared to other left ventricular assist devices and can therefore be used in smaller sized pediatric patients. We present our initial experience using the HVAD as a bridge to heart transplantation in the pediatric population. Read More

    A Motion Analysis Protocol for Kinematic Assessment of Poly-Articulated Prosthetic Hands With Cosmetic Gloves.
    Artif Organs 2017 Oct 13. Epub 2017 Oct 13.
    Unit of Biomedical Robotics and Biomicrosystems, Università Campus Bio-Medico di Roma, Rome, Italy.
    To provide upper-limb amputees with devices that best fit their needs and to test innovative solutions, it is necessary to quantitatively appraise a device performance with rigorous measurement methods. The aim of this work was to define an optimal motion analysis protocol, suitable for optoelectronic systems, to measure the kinematics of poly-articulated hands even when covered by a cosmetic glove. This is a fundamental aspect, because gloves can decrease device speed and range of motion and, ultimately, patients' acceptance of the artificial limb. Read More

    Oral Mucosa Model for Electrochemotherapy Treatment of Dog Mouth Cancer: Ex Vivo, In Silico, and In Vivo Experiments.
    Artif Organs 2017 Oct 13. Epub 2017 Oct 13.
    Oncology Veterinary, Vet Cancer, São Paulo, Brazil.
    Electrochemotherapy (EQT) is a local cancer treatment well established to cutaneous and subcutaneous tumors. Electric fields are applied to biological tissue in order to improve membrane permeability for cytotoxic drugs. This phenomenon is called electroporation or electropermeabilization. Read More

    Filter Adsorption of Anidulafungin to a Polysulfone-Based Hemofilter During CVVHD In Vitro.
    Artif Organs 2017 Oct 13. Epub 2017 Oct 13.
    Department of Anaesthesiology, University Hospital Regensburg, Regensburg, Germany.
    Candidemia is frequent in critically ill patients, especially in combination with an acute kidney injury (AKI). Echinocandins generally are recommended for therapy of such infections. Recent studies found no need for dosage adjustment in patients with end-stage renal disease receiving hemodialysis, or patients with AKI receiving continuous venovenous hemofiltration. Read More

    Real-Time ECG Simulation for Hybrid Mock Circulatory Loops.
    Artif Organs 2017 Oct 12. Epub 2017 Oct 12.
    Chair of Medical Information Technology, RWTH Aachen, Aachen, Germany.
    Classically, mock circulatory loops only simulate mechanical properties of the circulation. To connect the hydraulic world with electrophysiology, we present a real-time electrical activity model of the heart and show how to integrate this model into a real-time mock loop simulation. The model incorporates a predefined conduction pathway and a simplified volume conductor to solve the bidomain equations and the forward problem of electrocardiography, resulting in a physiological simulation of the electrocardiogram (ECG) at arbitrary electrode positions. Read More

    Welcome to "24 +1 = 25" the Quarter Century Anniversary Meeting of Our Society: Evolving to the International Society for Mechanical Circulatory Support.
    Artif Organs 2017 Oct;41(10):888-889
    Congress Chairman of ISMCS 2017, Professor of Medicine - Cardiology, Professor and Associate Department Head - BioMedical Engineering, Professor of Materials Sciences and Engineering, Professor of Medical Imaging, McGuire Scholar, Eller College of Management, Director - ACABI - Arizona Center for Accelerated BioMedical Innovation, Sarver Heart Center, University of Arizona, Tucson, AZ, USA.

    Change in Axial Rotation of the Femur in the Resting Supine Position Following Total Hip Arthroplasty.
    Artif Organs 2017 Oct 3. Epub 2017 Oct 3.
    Department of Orthopaedic Medical Engineering, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
    Stem anteversion in the setting of total hip arthroplasty (THA) is usually measured by referencing the posterior condylar line (PCL). However, stem anteversion may not express the functional torsion of the femur if a consistent horizontal tilt in the PCL is observed after THA. Herein, the horizontal tilt of the PCL at the resting neutral position of the hip was retrospectively measured in 53 THA patients from three computed tomography (CT) datasets: (i) preoperative (preop-CT), (ii) 3 weeks after THA (1st postop-CT), and (iii) more than 2 years after THA (2nd postop-CT). Read More

    Application of a Simplified Hand-Sewn Trileaflet Valved Conduit in Right Ventricular Outflow Tract Reconstruction as an Alternative for Bovine Jugular Vein Graft: Single-Center Experience.
    Artif Organs 2017 Oct 2. Epub 2017 Oct 2.
    Department of Cardiovascular Surgery, Children's Hospital of Fudan University, Shanghai, China.
    The Bovine jugular vein (BJV) graft for right ventricular outflow tract reconstruction (RVOT) is limited applied due to possible graft failure. In this study, we reported the clinical application of simplified hand-sewn trileaflet valved conduit as an alternative for BJV graft. We retrospectively included 68 patients underwent 76 conduits implantation including 22 new simplified hand-sewn trileaflet valved conduits (Group A) and 54 BJV grafts (Group B). Read More

    Evaluation of Combined Extracorporeal Life Support and Continuous Renal Replacement Therapy on Hemodynamic Performance and Gaseous Microemboli Handling Ability in a Simulated Neonatal ECLS System.
    Artif Organs 2017 Sep 21. Epub 2017 Sep 21.
    Penn State Health Pediatric Cardiovascular Research Center, Department of Pediatrics, Penn State Health Children's Hospital, Hershey, PA, USA.
    The objective of this study was to evaluate the hemodynamic performance and gaseous microemboli (GME) handling ability of a simulated neonatal extracorporeal life support (ECLS) circuit with an in-line continuous renal replacement therapy (CRRT) device. The circuit consisted of a Maquet RotaFlow centrifugal pump or HL20 roller pump, Quadrox-iD Pediatric diffusion membrane oxygenator, 8-Fr arterial cannula, 10-Fr venous cannula, and Better-Bladder (BB) with "Y" connector. A second Quadrox-I Adult oxygenator was added postarterial cannula for GME experiments. Read More

    Systematic Design of a Magnetically Levitated Brushless DC Motor for a Reversible Rotary Intra-Aortic Blood Pump.
    Artif Organs 2017 Oct 20;41(10):923-933. Epub 2017 Sep 20.
    Department of Engineering, University of Cambridge, Cambridge, UK.
    The IntraVAD is a miniature intra-aortic ventricular assist device (VAD) designed to work in series with the compromised left ventricle. A reverse-rotation control (RRc) mode has been developed to increase myocardial perfusion and reduce ventricular volume. The RRc mode includes forward rotation in systole and reverse rotation in diastole, which requires the IntraVAD to periodically reverse its rotational direction in synchrony with the cardiac cycle. Read More

    Extracorporeal Membrane Oxygenation Can Save Lives in Children With Heart or Lung Failure After Liver Transplantation.
    Artif Organs 2017 Sep;41(9):862-865
    Pediatric Intensive Care Unit, Hôpital Universitaire Necker-Enfants Malades, Paris, Île-de-France, France.
    The risk of cardiac or lung failure after liver transplantation (LT) is significant. In rare cases, the usual intensive care techniques fail to maintain organ oxygenation with a risk of multiorgan dysfunction. Although extracorporeal membrane oxygenation (ECMO) is a difficult and risky procedure, it can be proposed as life-saving. Read More

    Improvement of Decellularization Efficiency of Porcine Aorta Using Dimethyl Sulfoxide as a Penetration Enhancer.
    Artif Organs 2017 Sep 15. Epub 2017 Sep 15.
    Institute of Science and Technology in Medicine, School of Medicine, Keele University, Stoke-on-Trent, UK.
    Decellularization of tissues and organs enables researchers to obtain extracellular matrix (ECM) with the natural conformation and chemical composition of specific tissues. However, drawbacks exist such as the structural alteration of ECM or loss of some important components in ECM due to overexposure to chemicals during the decellularization process. In this study, porcine aorta was decellularized by sodium dodecyl sulfate (SDS). Read More

    Is Multiple Overlapping Uncovered Stents Technique Suitable for Aortic Aneurysm Repair?
    Artif Organs 2017 Sep 11. Epub 2017 Sep 11.
    Biomedical Engineering, National University of Singapore, Singapore.
    A computational fluid dynamic model to assess the impact of flow-diverter device on intra-aneurysmal flow in complex aortic aneurysm from the viewpoint of hemodynamics is presented. The aim of this study is to investigate the hemodynamic effects of an endovascular flow-diverter technique using multiple overlapping uncovered stents (MOUS) in the treatment of complex aortic aneurysm involving side branch. The placement of porous barrier such as MOUS across the aneurysm alters the blood flow pattern in the aneurysm sac. Read More

    Design and Development of Novel Transcatheter Bicaval Valves in the Interventional Treatment of Tricuspid Regurgitation.
    Artif Organs 2017 Sep 11. Epub 2017 Sep 11.
    Department of Biomedical Engineering, National University of Singapore, Singapore.
    The concept of heterotopic implantation of transcatheter tricuspid valve is new and has shown promising results thus far. While the Reynolds shear stress values measured in the vicinity of this valve are relatively low, the values at some time points are higher than the threshold of platelet activation. Hence, in this study, we aim to reduce these values with an innovative stent design. Read More

    Stable Control of Physiological Parameters, But Not Infection, in Preterm Lambs Maintained on Ex Vivo Uterine Environment Therapy.
    Artif Organs 2017 Oct 11;41(10):959-968. Epub 2017 Sep 11.
    School of Women's and Infants' Health, The University of Western Australia, Crawley, Western Australia, Australia.
    Ex vivo uterine environment (EVE) therapy is an experimental neonatal intensive care strategy wherein gas exchange is performed by membranous oxygenators attached to the umbilical vessels. Our aim was to assess the ability of a newly refined EVE system to maintain key physiological parameters in preterm lambs within optimal ranges for 48 h. EVE group; n = 6: Preterm lambs were delivered under general anesthesia at 115 ± 2 days of gestational age. Read More

    Circulatory Flow Restoration Versus Cardiopulmonary Resuscitation: New Therapeutic Approach in Sudden Cardiac Arrest.
    Artif Organs 2017 Sep 8. Epub 2017 Sep 8.
    Biosurgical Research Laboratory, Alain Carpentier Foundation, Pompidou Hospital, University of Paris Descartes, Paris, France.
    Sudden cardiac arrest (SCA) remains a major problem for health authorities worldwide. Insufficiencies of current cardiopulmonary resuscitation (CPR) are most probably related to an inappropriate concept and applied methods that still concentrate on heartbeat as priority, instead of blood circulation to maintain organs' perfusions. The aim of this works is to propose a new therapeutic approach for SCA in a more effective and secure manner compared with current CPR methods. Read More

    Incidence, Risk Factors, and Outcomes of Hyperbilirubinemia in Adult Cardiac Patients Supported by Veno-Arterial ECMO.
    Artif Organs 2017 Sep 6. Epub 2017 Sep 6.
    Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
    The aims of this study were to evaluate the incidence, risk factors, and outcomes of hyperbilirubinemia in cardiac patients with veno-arterial (VA) ECMO. Data on 89 adult patients with cardiac diseases who received VA ECMO implantation in our hospital were retrospectively reviewed. All patients were divided into the following three groups: 24 in normal group (N, total bilirubin [TBIL] ≤3 mg/dL), 30 in high bilirubin group (HB, 6 mg/dL ≥ TBIL > 3 mg/dL), and 35 in severe high bilirubin group (SHB, TBIL > 6 mg/dL). Read More

    Oxidative Stress Increases Erythrocyte Sensitivity to Shear-Mediated Damage.
    Artif Organs 2017 Sep 6. Epub 2017 Sep 6.
    Menzies Health Institute, Griffith University, Queensland, Australia.
    Patients receiving mechanical circulatory support often present with heightened inflammation and free radical production associated with pre-existing conditions in addition to that which is due to blood interactions with nonbiological surfaces. The aim of this experimental laboratory study was to assess the deformability of red blood cells (RBC) previously exposed to oxygen free radicals and determine the susceptibility of these cells to mechanical forces. In the present study, RBC from 15 healthy donors were washed and incubated for 60 min at 37°C with 50 µM phenazine methosulfate (PMS; an agent that generates superoxide within RBC). Read More

    Comparable Outcome of Out-of-Hospital Cardiac Arrest and In-Hospital Cardiac Arrest Treated With Extracorporeal Life Support.
    Artif Organs 2017 Sep 6. Epub 2017 Sep 6.
    Service d'Anesthésie Réanimation, CHU de Dijon, Dijon, France.
    Extracorporeal life support (ECLS) has shown benefits in the management of refractory in-hospital cardiac arrest (IHCA) by improving survival. Nonetheless, the results concerning out-of-hospital refractory cardiac arrests (OHCA) remain uncertain. The aim of our investigation was to compare survival between the two groups. Read More

    Hemodynamic Evaluation of a Biological and Mechanical Aortic Valve Prosthesis Using Patient-Specific MRI-Based CFD.
    Artif Organs 2017 Aug 29. Epub 2017 Aug 29.
    Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany.
    Modeling different treatment options before a procedure is performed is a promising approach for surgical decision making and patient care in heart valve disease. This study investigated the hemodynamic impact of different prostheses through patient-specific MRI-based CFD simulations. Ten time-resolved MRI data sets with and without velocity encoding were obtained to reconstruct the aorta and set hemodynamic boundary conditions for simulations. Read More

    The AB Portable Driver Generates Higher Drive-Line Pressures Possibly Leading to Accelerated Hemolysis.
    Artif Organs 2017 Aug 29. Epub 2017 Aug 29.
    Department of Cardiovascular Surgery, Yokohama City University, Yokohama, Japan.
    The AB5000 Circulatory Support System is paracorporeal pulsatile ventricular assist device. The AB Portable Driver is a portable console for this system. We experienced two cases with accelerated hemolysis while receiving support by the AB Portable Driver. Read More

    A Novel Three-Compartmental Model for Artificial Pancreas: Development and Validation.
    Artif Organs 2017 Aug 29. Epub 2017 Aug 29.
    Faculty of Engineering, University Campus Biomedico of Rome, Rome, Italy.
    Closed-loop insulin delivery system, also known as artificial pancreas (AP), provides the blood glucose control in diabetic patients, enabling the automatic blood-sugar management and reducing the risks and improving the lives of people with diabetes. A new three-compartmental model of glucose-insulin interaction for AP is presented and tested in this paper. The glucose and insulin "spaces" are split into a plasma compartment and interstitial fluids compartment, respectively. Read More

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