2,058 results match your criteria Artificial Cells Nanomedicine and Biotechnology[Journal]


Potential applications of PEGylated green gold nanoparticles in cyclophosphamide-induced cystitis.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):130-146

Pharmacological Sciences Research Lab, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

We investigated the effect of green tea extract PEGylated gold nanoparticles (P-AuNPs) making use of its targeted and sustained drug delivery against cyclophosphamide (CYP)-induced cystitis. AuNPs were synthesized by reduction reaction of gold salts with green tea extract following the concept of green synthesis. Mostly spherical-shaped P-AuNPs were synthesized with an average size of 14. Read More

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December 2022

Protective effect and mechanism of low P50 haemoglobin oxygen carrier on isolated rat heart.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):121-129

Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China.

The protection of the isolated heart is very important in heart transplantation surgery, meanwhile, the ischaemia/reperfusion (I/R) of the isolated heart is the main cause of its damage. A timely supply of oxygen can significantly improve the prevention of myocardial ischaemia, however, the cardioprotective solution does not have an oxygen supply function. Haemoglobin Based on Oxygen Carriers (HBOCs) is a kind of nano-oxygen drug, which can effectively and timely supply oxygen to hypoxic organs and tissues. Read More

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December 2022

Ultrasound-sensitive cRGD-modified liposomes as a novel drug delivery system.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):111-120

Department of Chemical Engineering, College of Engineering, American University of Sharjah, Sharjah, United Arab Emirates.

Targeted liposomes enable the delivery of encapsulated chemotherapeutics to tumours by targeting specific receptors overexpressed on the surfaces of cancer cells; this helps in reducing the systemic side effects associated with the cytotoxic agents. Upon reaching the targeted site, these liposomes can be triggered to release their payloads using internal or external triggers. In this study, we investigate the use of low-frequency ultrasound as an external modality to trigger the release of a model drug (calcein) from non-targeted and targeted pegylated liposomes modified with cyclic arginine-glycine-aspartate (cRGD). Read More

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):83

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):84

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):81

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):82

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):85

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December 2022

Expression of Concern.

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Artif Cells Nanomed Biotechnol 2022 12;50(1):86

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):110

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):109

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):107

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2022 Dec;50(1):108

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December 2022

Antibacterial activity of nano zinc oxide green-synthesised from triveng. Leaves against clinical isolates: in vitro and in vivo study.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):96-106

Department of Pharmacognosy, Faculty of Pharmacy, Al Salam University, Al Gharbia, Egypt.

The increasing emergence of bacterial resistance is a challenge for the research community, thus novel antibacterial agents should be developed. Metal nanoparticles are promising antibacterial agents and could solve the problem of antibiotic resistance. Herein, we used methanol extract (GTME) to biogenically synthesise zinc oxide nanoparticles (ZnO-NPs). Read More

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December 2022

Effective detection of ZnO in nicotine using butterfly wing scales.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):87-95

Biomedical Physics Research Unit, Department of Physics, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand.

This study aimed to elucidate the optical functions of naturally butterfly wing scales precise control of morphology as an effective photonic sensor and confirm the content of metal oxide nanoparticles in surrounding nicotine. Metal oxide nanoparticles mixed with nicotine were deposited on the wing scales through the spin-coating method and hence investigated using optical microscopy and spectroscopy. Experimental results demonstrated that absorption intensities of ZnO and TiO mixed with nicotine on were remarkably enhanced. Read More

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December 2022

Evaluation of tenofovir disoproxil fumarate loaded silver nanoparticle on testicular morphology in experimental type-2 diabetic rats.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):71-80

Department of Human, Biological & Translational Medical Sciences, School of Medicine, University of Namibia, Hage Geingob Campus, Windhoek, Namibia.

Reproductive derangement and metabolic disorders in human immunodeficiency virus (HIV) infected persons require a nanoparticle delivery system to convey antiretroviral drugs to the anatomical sanctuary such as testis. This study investigated the effects of tenofovir disoproxil fumarate (TDF) loaded silver nanoparticles (AgNPs) on the testicular oxidative stress, inflammatory cytokines and histology in male diabetic rats. Thirty-six Sprague-Dawley rats weighing 230 ± 20 g were randomly divided into diabetic and non-diabetic groups ( = 18). Read More

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December 2022

Prevention of peritoneal adhesions formation by core-shell electrospun ibuprofen-loaded PEG/silk fibrous membrane.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):40-48

Department of Physiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

Adhesion bands are pathological fibrous tissues that create in the middle of tissues and organs, often reasons of intestinal obstruction, and female infertility. Here, we explored the anti-adhesive and inflammatory capacities of PEG/silk and Ibuprofen-loaded PEG/Silk core-shell nanofibrous membranes, respectively. The ibuprofen-loaded Silk Fibroin-Poly ethylene Glycol (SF-PEG) core-shell membrane was fabricated by electrospinning and considered in terms of morphology, surface wettability, drug release, and degradation. Read More

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December 2022

Trans ethosomal hybrid composites of naproxen-sulfapyridine in hydrogel carrier: anti-inflammatory response in complete Freund's adjuvant induced arthritis rats.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):59-70

Department of Pharmaceutical Chemistry, Drug Discovery Centre, Acharya & BM Reddy College of Pharmacy, Bengaluru, India.

Current treatment for Rheumatoid arthritis (RA) utilizes Disease-modifying antirheumatic drugs, non-steroidal anti-inflammatory drugs or its combination, to decrease joint inflammation. In the present study, naproxen (NAP) and sulfapyridine (SULF) ethosomes were prepared by a thin-film hydration technique using PL90G and cholesterol, later crosslinked with carbopol®934. The ethosomes and ethosomal hydrogel were evaluated for rheological properties, physico-chemical analysis, and study. Read More

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December 2022

Myogenic commitment of human stem cells by myoblasts Co-culture: a static vs. a dynamic approach.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):49-58

Translational Medicine Laboratory, Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Salerno (SA), Italy.

An model of human bone marrow mesenchymal stem cells (BM-MSCs) myogenic commitment by synergic effect of a differentiation media coupled with human primary skeletal myoblasts (SkMs) co-culture was developed adopting both conventional static co-seeding and perfused culture systems. Static co-seeding provided a notable outcome in terms of gene expression with a significant increase of (141-fold) and (MYH2, 32-fold) at day 21, clearly detected also by semi-quantitative immunofluorescence. Under perfusion conditions, myogenic induction ability of SkMs on BM-MSCs was exerted by paracrine effect with an excellent gene overexpression and immunofluorescence detection of MYH2 protein; furthermore, due to the dynamic cell culture in separate wells, western blot data were acquired confirming a successful cell commitment at day 14. Read More

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December 2022

Co-delivery of STAT3 siRNA and methotrexate in breast cancer cells.

Artif Cells Nanomed Biotechnol 2022 Dec;50(1):29-39

iNANO Center, Aarhus University, Aarhus C, Denmark.

Co-delivery of anticancer drugs and biologics can provide synergetic effects and outperform single delivery therapies. Here, a nanoparticle (NP) system for co-delivery of methotrexate (MTX) and STAT3 siRNA has been developed and tested . Mesoporous silica nanoparticles (MSNs) were functionalized with chitosan (ch) by covalent grafting mediated by aminopropyl triethoxysilane (APTES) via glutaraldehyde as the linker. Read More

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December 2022

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2021 Dec;49(1):678

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December 2021

Expression of Concern.

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Artif Cells Nanomed Biotechnol 2021 12;49(1):675

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December 2021

Expression of Concern.

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Artif Cells Nanomed Biotechnol 2021 12;49(1):161

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December 2021

Expression of Concern.

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Artif Cells Nanomed Biotechnol 2021 12;49(1):162

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December 2021

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2021 Dec;49(1):157

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December 2021

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2021 Dec;49(1):158

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December 2021

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2021 Dec;49(1):681

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December 2021

Expression of Concern.

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Artif Cells Nanomed Biotechnol 2021 12;49(1):673

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December 2021

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2021 Dec;49(1):160

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December 2021

Statement of Retraction.

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Artif Cells Nanomed Biotechnol 2021 Dec;49(1):674

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December 2021