23,884 results match your criteria Arthritis Care & Research[Journal]


Combining primary care surveillance and a meta-analysis to estimate the incidence of the clinical manifestations of Lyme borreliosis in Belgium, 2015-2017.

Ticks Tick Borne Dis 2018 Dec 28. Epub 2018 Dec 28.

Scientific Directorate of Epidemiology and public health, Sciensano, J. Wytsmanstraat 14, 1050, Brussels, Belgium. Electronic address:

Lyme borreliosis (LB) is an important tick-borne disease which can cause a broad range of symptoms mainly affecting the skin, the nervous system and the joints. This study aims to estimate the incidence of the different clinical manifestations of LB in Belgium. The incidence of erythema migrans (EM) was estimated through the network of sentinel general practices at 97. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.12.007DOI Listing
December 2018

Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities.

J Am Acad Dermatol 2019 Feb 7. Epub 2019 Feb 7.

Baylor Scott and White, Dallas, Texas.

Psoriasis is a chronic, inflammatory, multisystem disease that affects up to 3.2% of the US population. This guideline addresses important clinical questions that arise in psoriasis management and care, providing recommendations on the basis of available evidence. Read More

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http://dx.doi.org/10.1016/j.jaad.2018.11.058DOI Listing
February 2019

Mediastinal, retroperitoneal, and subcutaneous emphysema due to sigmoid colon penetration: A case report and literature review.

Int J Surg Case Rep 2019 Feb 10;55:213-217. Epub 2019 Feb 10.

Department of Acute Care Surgery, Shimane University, Faculty of Medicine, Shimane, Japan.

Introduction: Mediastinal and subcutaneous emphysema usually result from spontaneous rupture of the alveolar wall. We present an extremely rare case of massive mediastinal, retroperitoneal, and subcutaneous emphysema due to the penetration of the colon into the mesentery.

Presentation Of Case: A 57-year-old man presented to our institution with a history of chest pain. Read More

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http://dx.doi.org/10.1016/j.ijscr.2019.02.003DOI Listing
February 2019

Measurement of synovial tissue volume in knee osteoarthritis using a semiautomated MRI-based quantitative approach.

Magn Reson Med 2019 Feb 15. Epub 2019 Feb 15.

Centre for Imaging Sciences, Division of Informatics, Imaging and Data Science, University of Manchester, Manchester, United Kingdom.

Purpose: Synovitis is common in knee osteoarthritis and is associated with both knee pain and progression of disease. Semiautomated methods have been developed for quantitative assessment of structure in knee osteoarthritis. Our aims were to apply a novel semiautomated assessment method using 3D active appearance modeling for the quantification of synovial tissue volume (STV) and to compare its performance with conventional manual segmentation. Read More

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http://dx.doi.org/10.1002/mrm.27633DOI Listing
February 2019

Endorsement of the 66/68 joint count for the measurement of musculoskeletal disease activity: OMERACT 2018 Psoriatic Arthritis workshop report.

J Rheumatol 2019 Feb 15. Epub 2019 Feb 15.

Division of Rheumatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore University of Leeds, Leeds, UK, and University of Oxford, Oxford, UK Musculoskeletal Health and Outcomes Research, St. Michael's Hospital, and Institute for Work and Health, and Department of Occupational Science and Occupational Therapy, Rehabilitation Sciences Institute and the Institute for Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada. Musculoskeletal Statistics Unit: The Parker Institute, Bispebjerg and Frederiksberg Hospital & Department of Rheumatology, Odense University Hospital, Denmark Division of Rheumatology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA Department of Medical Humanities, Patient Research Partner, Amsterdam University Medical Centre, , Amsterdam, The Netherlands. Department of Medicine, University of Toronto, Women's College Hospital, Toronto, ON, Canada Pfizer Inc., Montreal, QC, Canada Department of Rheumatology, St Vincent's University Hospital and Conway Institute for Biomolecular Research, University College Dublin, Ireland. Department of Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada Patient Research Partner; Division of Rheumatology, Duke University School of Medicine, Durham, NC; Kezar Life Sciences, South San Francisco, CA, USA Division of Rheumatology, Duke University School of Medicine, Durham, NC, USA Royal Prince Alfred Hospital Medical Centre, Sydney, Australia Patient Research Partner, employed by Amgen Inc, Thousand Oaks, CA, USA Cochrane Musculoskeletal Group, Ottawa Hospital Research Institute, Centre for Practice-Changing Research, Ottawa, ON, Canada Swedish-Providence-St. John's Health Systems and University of Washington, Seattle, WA, USA Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA Ottawa Hospital Research Institute, and School of Epidemiology and Public Health, University of Ottawa, ON, Canada Division of Immunology/Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA St. Vincent's University Hospital and University College Dublin, Dublin, Ireland Royal National Hospital for Rheumatic Diseases and the University of Bath, Bath, UK. Address correspondence to Alexis Ogdie, MD, University of Pennsylvania, White Building Room 5023, 3400 Spruce St, Philadelphia, Pennsylvania 19104, United States. E-mail:

Objective: The psoriatic arthritis (PsA) core domain set for randomized controlled trials (RCTs) and longitudinal observational studies (LOS) has recently been updated. The joint counts are central to the measurement of the peripheral arthritis component of the musculoskeletal (MSK) disease activity domain. We report the Outcome Measures in Rheumatology (OMERACT) 2018 meeting approaches to seek endorsement of the 66/68-swollen and tender joint count (SJC66/TJC68) for inclusion in the PsA Core Outcome Measurement Set. Read More

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http://dx.doi.org/10.3899/jrheum.181089DOI Listing
February 2019

Development and Validation of an OMERACT MRI Whole-Body Score for Inflammation in Peripheral Joints and Entheses in Inflammatory Arthritis (MRI-WIPE).

J Rheumatol 2019 Feb 15. Epub 2019 Feb 15.

From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Diagnostic Imaging, Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; University Pierre et Marie Curie - Paris 6, Sorbonne Universités, GRC-08 (EEMOIS); APHP, Rheumatology Dept., Pitié Salpêtrière University Hospital, Paris, France; Division of Medicine, University of New South Wales, Sydney, Australia; Department of Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India; Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada; CaRE Arthritis, Edmonton, Canada; Department of Medicine, University of Alberta, Edmonton, Canada; Department of Rheumatology, Cliniques Universitaires Saint-Luc, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain, Brussels, Belgium; Department of Radiology, Ghent University Hospital, Belgium; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, & NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospital NHS Trust, United Kingdom; Department of Radiology, Arthritis Imaging Research Group, University Hospital Charité, Berlin, Germany; 14Spire Sciences, Inc., Boca Raton, Florida, United States. S.K. received research grants from The Danish Rheumatism Association and Rigshospitalet. Address correspondence to Simon Krabbe, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Valdemar Hansens Vej 17, DK-2600 Glostrup, Denmark. E-mail:

Objective: To develop a whole-body MRI-scoring system for peripheral arthritis and enthesitis.

Methods: After consensus on definitions/locations of MRI pathologies, four multi-reader exercises were performed. Eighty-three joints were scored 0-3 separately for synovitis and osteitis, thirty-three entheses 0-3 separately for soft tissue inflammation and osteitis. Read More

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http://dx.doi.org/10.3899/jrheum.181084DOI Listing
February 2019

An Update on Arthritis in Canada - National and Provincial Data Regarding the Past, Present, and Future.

J Rheumatol 2019 Feb 15. Epub 2019 Feb 15.

From the Dalla Lana School of Public Health, University of Toronto; Health Care and Outcomes Research, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada. E.M. Badley, DPhil, Dalla Lana School of Public Health, University of Toronto, and Health Care and Outcomes Research, Krembil Research Institute, University Health Network; C.M. Goulart, MPH, Dalla Lana School of Public Health, University of Toronto; D.B. Millstone, MPH, Health Care and Outcomes Research, Krembil Research Institute, University Health Network; A.V. Perruccio, PhD, Dalla Lana School of Public Health, University of Toronto, and Health Care and Outcomes Research and Arthritis Program, Krembil Research Institute, University Health Network, and Department of Surgery, Faculty of Medicine, University of Toronto. Address correspondence to Dr. E.M. Badley, Krembil Research Institute, Toronto Western Hospital, MP 10-310, 399 Bathurst St., Toronto, Ontario M5T 2S8, Canada. E-mail: Accepted for publication October 10, 2018.

Objective: To provide updated arthritis estimates for Canada given a change in wording in the 2015 Canadian Community Health Survey (CCHS) arthritis question.

Methods: Prevalence data from the 2000 to 2016 CCHS were used to document trends in the prevalence of arthritis over time. Projections of arthritis prevalence were also calculated using data from CCHS 2015 in conjunction with Statistics Canada's published population projections. Read More

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http://dx.doi.org/10.3899/jrheum.180147DOI Listing
February 2019

Establishing an updated core domain set for studies in juvenile idiopathic arthritis: a report from the OMERACT 2018 JIA Workshop.

J Rheumatol 2019 Feb 15. Epub 2019 Feb 15.

E.M. Morgan MD, Associate Professor, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, J.E. Munro MBBS, Associate Professor, Head of Rheumatology at the Royal Children's Hospital, Melbourne, Australia and Group Leader Arthritis research, Murdoch Children's Research Institute Melbourne Australia, J. Horonjeff, PhD, Instructor, Office of Research, Division of Rheumatology, Columbia University Medical Center, New York, NY, B. Horgan, Consumer Advocate, Consumer and Community Health Research Network, Australia, B. Shea, PhD, Clinical Investigator, Ottawa Hospital Research Institute, Adjunct Professor, School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada, B.M. Feldman, MD, MSc, FRCPC, Professor Pediatrics, Medicine, Institute of Health Policy Management & Evaluation, University of Toronto, Head, Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, H. Clairman, M.Sc., Clinical Research Project Coordinator, Child Health Evaluative Sciences, Hospital for Sick Children, Toronto ON, C.O. Bingham III, MD; Professor of Medicine, Division of Rheumatology, Johns Hopkins University, Baltimore, MD; S. Thornhill, AA, Qualitative Research Consultant, Thornhill Associates, Hermosa Beach, CA, V. Strand MD, Adjunct Clinical Professor, Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, A. Alongi, PhD Student, IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, and Università degli studi di Genova, Genoa, Italy, S. Magni-Manzoni, M.D. Rheumatology Division, Ospedale Pediatrico Bambino Gesù, Roma, Italy, M. A.J. van Rossum, MD PhD, Pediatric Rheumatologist/Immunologist, Amsterdam Rheumatology and Immunology Center / Reade l Emma Children's Hospital Amsterdam Medical Center, Amsterdam, R. Vesely, MD, Head of the Rheumatology, Respiratory, Gastroenterology and Immunology Office Scientific and Regulatory Management Department European Medicines Agency, London, United Kingdom J. Vojinovic, MD PhD, Professor, University of Nis, Faculty of Medicine, Department of Pediatric Rheumatology, Serbia H.I. Brunner, Professor, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, J.G. Harris, MD, Assistant Professor, Division of Rheumatology, Children's Mercy - Kansas City, Kansas City, MO, D.B. Horton, MD, MSCE, Assistant Professor, Division of Pediatric Rheumatology, Rutgers Robert Wood Johnson Medical School, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, D.J. Lovell, MD, Professor, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, M. Mannion, MD, Assistant Professor of Rheumatology, University of Alabama at Birmingham, Birmingham, AL, H. Rahimi, MD, Assistant Professor, Division of Rheumatology, University of Rochester, Golisano Children's Hospital, Rochester, NY; A. Ravelli, MD, Professor of Pediatrics, Università degli Studi di Genova and IRCCS Istituto Giannina Gaslini, Genoa, Italy, S. Ringold, MD, Assistant Professor, Division of Rheumatology, Seattle Children's, Seattle, WA, Nicolino Ruperto, MD, MPH, IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, PRINTO, Genoa, M.S. Schrandt, J.D., Director, Patient Engagement, Arthritis Foundation, Atlanta, GA, S. Shenoi, MBBS, MS Associate Professor, Seattle Children's Hospital, Seattle, WA Natalie J. Shiff, MD, University of Florida, Shands Children's Hospital, Gainesville, FL, K. Toupin-April, PhD, Associate Scientist, Children's Hospital of Eastern Ontario Research Institute, Assistant Professor, Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa, Ottawa, Canada, N. Tzaribachev, MD, Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany, P. Weiss, MD, MSCE, Associate Professor, Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, A. Consolaro, MD, PhD, Assistant Professor, IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, and Università degli studi di Genova, Genoa, Italy, Address correspondence to: E.M. Morgan MD, Associate Professor of Pediatrics, Division of Rheumatology Cincinnati Children's Hospital Medical Center 3333 Burnet Ave, MLC 4010, Cincinnati, OH 45229; Email:

Objective: The current Juvenile Idiopathic Arthritis (JIA) Core Set used in randomized controlled trials (RCTs) and longitudinal observational studies (LOS) was developed without input of patients/parents. At OMERACT 2016, a special interest group voted to reconsider the core set incorporating broader stakeholder input. We describe subsequent work culminating in an OMERACT 2018 plenary and consensus voting. Read More

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http://dx.doi.org/10.3899/jrheum.181088DOI Listing
February 2019

Practice-Based Differences in Pediatric Discoid Lupus Erythematosus.

Br J Dermatol 2019 Feb 15. Epub 2019 Feb 15.

Northwestern University Feinberg School of Medicine, Department of Dermatology and Pediatrics, Chicago, Illinois, United States.

Background: Children with discoid lupus erythematosus (DLE) are at risk for disfigurement and progression to systemic lupus erythematosus (SLE). Consensus is lacking regarding optimal care of children with DLE.

Objectives: We compared practice patterns among pediatric dermatologists/rheumatologists treating pediatric DLE. Read More

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http://dx.doi.org/10.1111/bjd.17780DOI Listing
February 2019

Reply to comment by Dr Parperis and associates.

Authors:
Marie Holmqvist

Arthritis Care Res (Hoboken) 2019 Feb 15. Epub 2019 Feb 15.

Department of Medicine Solna, Rheumatology Unit, Karolinska Institutet and Rheumatology, Clinic Karolinska University Hospital, Stockholm, Sweden.

I appreciate the interesting review of corticosteroids and their impact on risk of venous thromboembolic events provided by Dr Parperis and associates. Corticosteroid use and its impact on comorbidities should definitely be closely followed in clinical practice. This article is protected by copyright. Read More

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http://dx.doi.org/10.1002/acr.23850DOI Listing
February 2019

Patient Perspectives on Smoking Cessation and Interventions in Rheumatology Clinics.

Arthritis Care Res (Hoboken) 2019 Feb 15. Epub 2019 Feb 15.

UW-SMPH Department of Medicine, Rheumatology, Madison, WI, United States.

Objective: Although smoking is a risk factor for cardiovascular and rheumatic disease severity, only 10% of rheumatology visits document cessation counseling. After implementing a rheumatology clinic protocol that increased tobacco quitline referrals 20-fold, current objectives were to 1) examine patients' barriers and facilitators to smoking cessation based on prior rheumatology experiences, 2) solicit reactions to the new cessation protocol, and 3) identify patient-centered outcomes or "signs of cessation progress" following improved care.

Methods: We recruited 19 patients who smoke-12 with rheumatoid arthritis (RA) and 7 with systemic lupus erythematosus (SLE)-to one of three semi-structured focus groups. Read More

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http://dx.doi.org/10.1002/acr.23858DOI Listing
February 2019

The mortality rate and causes of death among juvenile idiopathic arthritis patients in Finland.

Clin Exp Rheumatol 2019 Feb 11. Epub 2019 Feb 11.

Department of Children and Adolescents, Oulu University Hospital; Medical Research Centre, University of Oulu and Oulu University Hospital; and PEDEGO Research Unit, University of Oulu, Finland.

Objectives: To explore mortality rates and causes of death in juvenile idiopathic arthritis (JIA) patients in Finland compared with the general population.

Methods: All incident patients with JIA (age <16 years at the index day) during 2000-2014 were collected from the nationwide register maintained by the Social Insurance Institution of Finland and The National Population Registry identified three age-, sex- and residence-matched controls for each case. They were followed up together until 31st Dec 2015. Read More

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February 2019

Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome.

Pediatr Rheumatol Online J 2019 Feb 14;17(1). Epub 2019 Feb 14.

Division of Immunolgy, Boston Children's Hospital, Boston, MA, USA.

Background: Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) were historically thought to be distinct entities, often managed in isolation. In fact, these conditions are closely related. A collaborative approach, which incorporates expertise from subspecialties that previously treated HLH/MAS independently, is needed. Read More

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http://dx.doi.org/10.1186/s12969-019-0309-6DOI Listing
February 2019

Prevalence, Treatment and Outcomes of Coexistent Pulmonary Hypertension and Interstitial Lung Disease in Systemic Sclerosis.

Arthritis Rheumatol 2019 Feb 14. Epub 2019 Feb 14.

Division of Rheumatology, Department of Internal Medicine, University of Michigan.

Objective: Systemic sclerosis (SSc) is associated with interstitial lung disease (ILD) and pulmonary hypertension (PH). We sought to determine prevalence, characteristics, treatment, and outcomes for subjects with PH in a SSc-associated ILD (SSc-ILD) cohort.

Methods: Subjects with SSc-ILD on high resolution computed tomography (HRCT) were included in a prospective observational cohort. Read More

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http://dx.doi.org/10.1002/art.40862DOI Listing
February 2019

Venous Thromboembolic Events in Idiopathic Inflammatory Myopathy: Occurrence and Relation to Disease Onset: comment on the article by Antovic et al.

Arthritis Care Res (Hoboken) 2019 Feb 14. Epub 2019 Feb 14.

Maricopa Integrated Health System, 2601 E Roosevelt St, Phoenix, Arizona, 85008, USA.

I read with great interest the article by Antovic et al, recently published in Arthritis Care & Research (1). In a population-based study, the investigators demonstrated an increased risk of venous thromboembolic events (VTE) in patients with idiopathic inflammatory myopathy (IIM), compared with the general population. Strikingly, the hazard ratio for VTE was 26. Read More

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http://dx.doi.org/10.1002/acr.23856DOI Listing
February 2019

Chronic medical conditions in U.S. adults with incarceration history.

Authors:
Tomoko Udo

Health Psychol 2019 Mar;38(3):217-225

University at Albany, State University of New York.

Objectives: To examine the associations between incarceration history and chronic medical conditions in a nationally representative sample of U.S. adults and whether risk for chronic medical conditions differ by sex and race among those with incarceration history. Read More

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http://doi.apa.org/getdoi.cfm?doi=10.1037/hea0000720
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http://dx.doi.org/10.1037/hea0000720DOI Listing
March 2019
2 Reads

Men and women's occupational activities and the risk of developing osteoarthritis of the knee, hip or hands: A systematic review and recommendations for future research.

Arthritis Care Res (Hoboken) 2019 Feb 14. Epub 2019 Feb 14.

Occupational Science & Occupational Therapy, University of British Columbia, Vancouver, B.C., Canada.

Objective: To systematically review the evidence for an increased risk of osteoarthritis in the hip, knee, hand, wrist, finger, ankle, foot, shoulder, neck and spine related to men and women's diverse occupational activities and to examine dose response information related to the frequency, intensity, and duration of work exposures and the risk of OA.

Methods: Established guidelines for systematic reviews in occupational health and safety studies were followed. MEDLINE, EMBASE, CINAHL and Cochrane Library were searched from inception to December 2017. Read More

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http://dx.doi.org/10.1002/acr.23855DOI Listing
February 2019

Patient-reported outcomes 1 to 5 years after ACL reconstruction: effect of combined injury, and associations with MRI-defined osteoarthritis features.

Arthritis Care Res (Hoboken) 2019 Feb 14. Epub 2019 Feb 14.

La Trobe Sport & Exercise Medicine Research Centre, School of Allied Health, La Trobe University, Bundoora, Australia.

Objective: Persistent symptoms and poor quality of life (QoL) are common following anterior cruciate ligament reconstruction (ACLR). We aimed to determine the influence of a combined ACL injury (i.e. Read More

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http://dx.doi.org/10.1002/acr.23854DOI Listing
February 2019
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The impact of smoking on response to TNF inhibitors in axial spondyloarthritis: methodological considerations for longitudinal observational studies.

Arthritis Care Res (Hoboken) 2019 Feb 14. Epub 2019 Feb 14.

Musculoskeletal biology I, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

Objective: Observational data facilitate examination of treatment-effect heterogeneity, but the risk of bias is substantial. We highlight methodological considerations through an analysis of whether smoking affects response to TNF inhibitors (TNFi) in axial spondyloarthritis (axSpA).

Methods: We used longitudinal data from the British Society for Rheumatology Biologics Register for Ankylosing Spondylitis. Read More

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http://dx.doi.org/10.1002/acr.23851DOI Listing
February 2019

Modifiable Determinants of Exercise Use in a Diverse Ethnic Population with Osteoarthritis.

Arthritis Care Res (Hoboken) 2019 Feb 14. Epub 2019 Feb 14.

University of Arizona Arthritis Center, Tucson, AZ.

Objectives: To determine the extent of ethnic differences in using exercise for therapy and Identify relevant modifiable determinants of exercise use among knee/hip osteoarthritis (OA) patients METHODS: Knee/hip OA study participants were identified. Surveys were administered to collect patient socio-demographics, clinical information, and beliefs and attitudes about providers and treatments. Final multivariable logistic regression models were created using a fully conditional method. Read More

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http://dx.doi.org/10.1002/acr.23852DOI Listing
February 2019

Long-term outcomes in juvenile idiopathic arthritis: 18 years of follow-up in the population-based Nordic Juvenile Idiopathic Arthritis (JIA) cohort.

Arthritis Care Res (Hoboken) 2019 Feb 14. Epub 2019 Feb 14.

Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark.

Objectives: This study assessed the long-term course, remission rate and disease burden in juvenile idiopathic arthritis (JIA) 18 years after disease onset in a population-based setting from the early biologic era.

Methods: A total of 510 consecutive cases of JIA with disease onset between 1997 and 2000 from defined geographic regions in Denmark, Norway, Sweden and Finland were prospectively included in this 18-year cohort study. At the follow-up visit, patient-reported, demographic and clinical data were collected. Read More

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http://dx.doi.org/10.1002/acr.23853DOI Listing
February 2019

Long-term efficacy and safety of biosimilar infliximab (CT-P13) after switching from originator infliximab: Open-label extension of the NOR-SWITCH trial.

J Intern Med 2019 Feb 14. Epub 2019 Feb 14.

Department of Rheumatology, Diakonhjemmet Hospital, Oslo.

Background And Objectives: The 52-week, randomized, double blind, non-inferiority, government funded NOR-SWITCH trial demonstrated that switching from infliximab originator to less expensive biosimilar CT-P13 was not inferior to continued treatment with infliximab originator. The NOR-SWITCH extension trial aimed to assess efficacy, safety and immunogenicity in patients on CT-P13 throughout the 78-week study period (maintenance group) vs patients switched to CT-P13 at week 52 (switch group).

Primary Outcome: disease worsening during follow-up based on disease specific composite measures. Read More

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http://dx.doi.org/10.1111/joim.12880DOI Listing
February 2019

Synovial Tissue Sampling in Rheumatological Practice-Past Developments and Future Perspectives.

Authors:
Frances C Humby

Front Med (Lausanne) 2019 29;6. Epub 2019 Jan 29.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

Synovial biopsies are performed in routine clinical care in order to refine diagnosis as well as within a research setting. Progress in the development of minimally invasive synovial sampling methods in the last century has accelerated and facilitated novel insights into disease pathogenesis. This review discusses the development of synovial biopsy techniques as well as examining the three currently most commonly used approaches: arthroscopic, blind needle biopsy and ultrasound guided approaches. Read More

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http://dx.doi.org/10.3389/fmed.2019.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361834PMC
January 2019

How common is imaging for low back pain in primary and emergency care? Systematic review and meta-analysis of over 4 million imaging requests across 21 years.

Br J Sports Med 2019 Feb 13. Epub 2019 Feb 13.

Institute for Musculoskeletal Health, The University of Sydney, Sydney Medical School, School of Public Health, Sydney, New South Wales, Australia.

Objectives: To (1) estimate the proportion of patients seeking care for low back pain (LBP) who are imaged and (2) explore trends in the proportion of patients who received diagnostic imaging over time. We also examined the effect of study-level factors on estimates of imaging proportion.

Data Sources: Electronic searches of MEDLINE, Embase and CINAHL databases from January 1995 to December 2017. Read More

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http://dx.doi.org/10.1136/bjsports-2018-100087DOI Listing
February 2019

Inflammasome Signaling and Impaired Vascular Health in Psoriasis.

Arterioscler Thromb Vasc Biol 2019 Feb 14:ATVBAHA118312246. Epub 2019 Feb 14.

From the Center for the Prevention of Cardiovascular Disease, Department of Medicine, New York University School of Medicine (M.S.G., E.A.F., J.S.B.).

Objective- Psoriasis is an inflammatory skin disease which heightens the risk of cardiovascular disease. This study directly investigated vascular endothelial health and systemically altered pathways in psoriasis and matched controls. Approach and Results- Twenty patients (mean age, 40 years; 50% male) with active psoriasis and 10 age-, sex-matched controls were recruited. Read More

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http://dx.doi.org/10.1161/ATVBAHA.118.312246DOI Listing
February 2019

Hip fracture care in Manitoba, Canada and New York State, United States: an analysis of administrative data.

CMAJ Open 2019 Jan-Mar;7(1):E55-E62. Epub 2019 Feb 11.

North American Observatory on Health Systems and Policies (Cram), Institute for Health Policy, Management and Evaluation, University of Toronto; Departments of Medicine (Cram) and Surgery (Gandhi), University of Toronto; Division of General Internal Medicine and Geriatrics (Cram), Sinai Health System and University Health Network, Toronto, Ont.; Departments of Community Health Sciences (Lix, Bohm, Yan, Roos), Surgery (Bohm) and Medicine (Leslie), University of Manitoba, Winnipeg, Man.; Biostatistics Research Unit (Matelski) and Arthritis Program (Gandhi), University Health Network, Toronto, Ont.; Department of Health Care Policy (Landon), Harvard Medical School; Division of General Medicine and Primary Care (Landon), Beth Israel Deaconess Medical Center, Boston, Mass.

Background: Nearly 30 years ago, a series of studies showed increased hip fracture mortality in Manitoba compared to the United States, but these data have not been updated. Our objective was to compare the organization of hip fracture care and short-term outcomes in Manitoba and New York State using contemporary data.

Methods: This was a retrospective cohort study of administrative data for all adults aged 50 years or more admitted to hospital with hip fracture between Jan. Read More

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http://dx.doi.org/10.9778/cmajo.20180126DOI Listing
February 2019

Investigating asthma, allergic disease, passive smoke exposure, and risk of rheumatoid.

Arthritis Rheumatol 2019 Feb 12. Epub 2019 Feb 12.

Mayo Clinic, Rheumatology, Mayo Building, 15-73E, 200 1st St SW, Rochester, Minnesota, United States.

Objective: Rheumatoid Arthritis (RA) is postulated to originate at mucosal surfaces, particularly the airway mucosa. To investigate this hypothesis, we determined the association between RA and asthma, passive smoke exposure, and age of starting smoking.

Methods: This case-control study identified 1,023 cases of RA (175 incident) within a single-center biobank population using a rules-based algorithm that combined self-report with two diagnosis codes. Read More

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http://dx.doi.org/10.1002/art.40858DOI Listing
February 2019
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Effect of COPD severity and comorbidities on the result of the PHQ-9 tool for the diagnosis of depression: results from the COSYCONET cohort study.

Respir Res 2019 Feb 11;20(1):30. Epub 2019 Feb 11.

Department of Internal Medicine V, University of Munich (LMU), Ziemssenstr. 1, 80336, Munich, Germany.

The diagnosis of depression, a frequent comorbidity of chronic obstructive pulmonary disease (COPD), is often supported by questionnaires, such as the Patient Health Questionnaire 9 (PHQ-9). It is unknown to which extent its single questions are affected by the clinical characteristics of COPD patients.We addressed this question in 2255 GOLD grade 1-4 patients from the COSYCONET (COPD and Systemic Consequences - Comorbidities Network) COPD cohort. Read More

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http://dx.doi.org/10.1186/s12931-019-0997-yDOI Listing
February 2019
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Children with Enthesitis Have Worse Quality of Life, Function, and Pain, Irrespective of their Juvenile Arthritis Category.

Arthritis Care Res (Hoboken) 2019 Feb 11. Epub 2019 Feb 11.

School of Public Health, University of Alberta.

Objective: To estimate the impact of enthesitis on patient-reported outcomes (PROs) in children with juvenile idiopathic arthritis (JIA), irrespective of JIA category.

Methods: Children in the Research in Arthritis in Canadian Children emphasizing Outcomes (ReACCh-Out) cohort were studied. Entheseal tenderness by physician examination in 33 defined locations, Juvenile Arthritis Quality of life Questionnaire (JAQQ), Quality of My Life questionnaire (QoML), Childhood Health Assessment Questionnaire (CHAQ), and a pain visual analogue scale (VAS) were completed at enrolment, every 6 months for 2 years, and then yearly up to 5 years. Read More

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http://dx.doi.org/10.1002/acr.23844DOI Listing
February 2019

Timing of Abatacept Before Elective Arthroplasty and Risk of Post-operative Outcomes.

Arthritis Care Res (Hoboken) 2019 Feb 11. Epub 2019 Feb 11.

University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology.

Objectives: Guidelines recommend holding biologic therapies before hip and knee arthroplasty, yet evidence to inform optimal timing is limited. We aimed to determine whether holding abatacept infusions is associated with lower risk of adverse post-operative outcomes.

Methods: This retrospective cohort study using U. Read More

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http://doi.wiley.com/10.1002/acr.23843
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http://dx.doi.org/10.1002/acr.23843DOI Listing
February 2019
3 Reads

US Adult Rheumatologists' Perspective on the Transition Process for Young Adults with Rheumatic Conditions.

Arthritis Care Res (Hoboken) 2019 Feb 11. Epub 2019 Feb 11.

Department of Pediatrics, Program in Immunology, Stanford University, Stanford, CA.

Objective: To assess the attitudes and common practices of adult rheumatologists in the United States regarding health care transition (HCT) for young adults with rheumatic diseases.

Methods: An anonymous online survey was sent to U.S. Read More

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http://dx.doi.org/10.1002/acr.23845DOI Listing
February 2019
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Automated text message enhanced monitoring versus routine monitoring in early rheumatoid arthritis: a randomized trial.

Arthritis Care Res (Hoboken) 2019 Feb 11. Epub 2019 Feb 11.

South Karelia Central Hospital, Lappeenranta, Finland.

Objective: Frequent monitoring of early rheumatoid arthritis (RA) patients is required for achieving good outcomes. We studied the influence of text message (SMS) enhanced monitoring on early RA outcomes.

Methods: We randomized 166 early, disease-modifying antirheumatic drug naive RA patients to SMS-enhanced follow-up or routine care. Read More

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http://doi.wiley.com/10.1002/acr.23846
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http://dx.doi.org/10.1002/acr.23846DOI Listing
February 2019
3 Reads

Three Quality Improvement Initiatives Improved Performance of Rheumatoid Arthritis Disease Activity Measures in Electronic Health Records: Results from an Interrupted Time Series Study.

Arthritis Care Res (Hoboken) 2019 Feb 11. Epub 2019 Feb 11.

Division of Rheumatology, UCSF and the Veterans Affairs Medical Center - San Francisco, San Francisco, CA.

Objective: Applying treat to target strategies in the care of patients with rheumatoid arthritis (RA) is critical for improving outcomes, yet electronic health records (EHRs) have few features to facilitate this strategy. We evaluated the effect of three health-IT initiatives on performance of RA disease activity measures and outcomes in an academic rheumatology clinic.

Methods: We implemented three initiatives designed to facilitate performance of the Clinical Disease Activity Index (CDAI): an EHR flowsheet to input scores, peer performance reports, and an EHR SmartForm including a CDAI calculator. Read More

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http://dx.doi.org/10.1002/acr.23848DOI Listing
February 2019
1 Read

Cotreatment with methotrexate in routine care patients with rheumatoid arthritis receiving biological treatment yields better outcomes over time.

RMD Open 2019 22;5(1):e000836. Epub 2019 Jan 22.

Department of Rheumatology, Zuyderland Medical Centre, Sittard-Geleen - Heerlen, The Netherlands.

Objectives: We aimed to evaluate the effects of methotrexate (MTX) comedication added to biological disease-modifying antirheumatic drugs (bDMARD) on disease activity measures in patients with rheumatoid arthritis (RA) in routine care.

Methods: Patients with RA on treatment with either bDMARDs or conventional synthetic DMARDs were included in this prospective cohort study. The effect of (time-varying) combination therapy with bDMARD and MTX compared with bDMARD monotherapy was tested in longitudinal generalised estimating equation models using as outcomes: (1) the likelihood to be in remission according to the 28-joint Disease Activity Score (DAS28) erythrocyte sedimentation rate (ESR) (<2. Read More

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http://dx.doi.org/10.1136/rmdopen-2018-000836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347027PMC
January 2019
1 Read

f(1Feature Extraction for Phenotyping from Semantic and Knowledge Resources.

J Biomed Inform 2019 Feb 7:103122. Epub 2019 Feb 7.

Center for Statistical Science, Tsinghua University, Beijing, China; Department of Industrial Engineering, Tsinghua University, Beijing, China; Institute for Data Science, Tsinghua University, Beijing, China. Electronic address:

Objective: Phenotyping algorithms can efficiently and accurately identify patients with a specific disease phenotype and construct electronic health records (EHR)-based cohorts for subsequent clinical or genomic studies. Previous studies have introduced unsupervised EHR-based feature selection methods that yielded algorithms with high accuracy. However, those selection methods still require expert intervention to tweak the parameter settings according to the EHR data distribution for each phenotype. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15320464193004
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http://dx.doi.org/10.1016/j.jbi.2019.103122DOI Listing
February 2019
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Trial of labor after cesarean section in risk pregnancies: a population-based cohort study.

Acta Obstet Gynecol Scand 2019 Feb 8. Epub 2019 Feb 8.

Department of Clinical Science, University of Bergen, Norway.

Introduction: In most pregnancies after a cesarean section, a trial of labor is an option. The objective of the study was to explore trial of labor and its failure in pregnancies with medical risk conditions, in a population with a high trial of labor rate.

Material And Methods: In a cohort study (n=57 109), using data from the Medical Birth Registry of Norway 1989-2014, women with a second delivery after a first pregnancy cesarean section were included. Read More

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http://dx.doi.org/10.1111/aogs.13565DOI Listing
February 2019
1 Read

Cost-effectiveness of sequential treatment with abaloparatide vs. teriparatide for United States women at increased risk of fracture.

Semin Arthritis Rheum 2019 Jan 10. Epub 2019 Jan 10.

Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium; Prince Mutaib Chair for Biomarkers of Osteoporosis, Biochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.

Objectives: There is emerging evidence supporting sequential therapy with an osteoanabolic followed by an antiresorptive in patients at high-risk of fragility fractures. This study assessed the cost-effectiveness of sequential treatment with abaloparatide (ABL) followed by alendronate (ALN) [(ABL/ALN)] compared with teriparatide (TPTD) followed by ALN (TPTD/ALN).

Methods: A previously validated Markov microsimulation model was adapted to estimate the cost-effectiveness of sequential ABL/ALN compared with sequential TPTD/ALN and no treatment with a lifetime horizon from the US payer perspective. Read More

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http://dx.doi.org/10.1016/j.semarthrit.2019.01.006DOI Listing
January 2019
1 Read

Chronic hepatitis B viral infection among RA patients-a cross-sectional control study.

Clin Rheumatol 2019 Feb 8. Epub 2019 Feb 8.

Department of Medicine 'B', Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, 52621, Tel-Hashomer, Israel.

Background And Objectives: Rheumatoid arthritis (RA) is the most common inflammatory joint disorder presenting also with extra-articular manifestations. As many other autoimmune diseases, it has been suggested that infectious diseases might contribute to its emergence. Hepatitis viruses were suggested by several reports as a trigger of RA onset. Read More

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http://link.springer.com/10.1007/s10067-019-04448-x
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http://dx.doi.org/10.1007/s10067-019-04448-xDOI Listing
February 2019
4 Reads

Arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of symptomatic femoroacetabular impingement: multicentre randomised controlled trial.

BMJ 2019 Feb 7;364:l185. Epub 2019 Feb 7.

Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences (NDORMS), University of Oxford, Botnar Research Centre, Oxford OX3 7LD, UK.

Objective: To compare arthroscopic hip surgery with physiotherapy and activity modification for improving patient reported outcome measures in patients with symptomatic femoroacetabular impingement (FAI).

Design: Two group parallel, assessor blinded, pragmatic randomised controlled trial.

Setting: Secondary and tertiary care centres across seven NHS England sites. Read More

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http://dx.doi.org/10.1136/bmj.l185DOI Listing
February 2019
1 Read

Outcomes among 196 patients with non-infectious proximal aortitis.

Arthritis Rheumatol 2019 Feb 7. Epub 2019 Feb 7.

Division of Rheumatic and Immunologic Diseases, Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Objective: Non-infectious aortitis may occur in the context of a recognized systemic disease or as a topographically-limited lesion without systemic features, termed clinically-isolated aortitis (CIA). From a large population of patients in a single center dedicated to aortic diseases, we have sought to better define and stress the limitations of this diagnostic category, and suggest recommendations for care.

Methods: Records of patients undergoing thoracic aortic surgery (1996-2012) at the Cleveland Clinic were reviewed to identify 196 with histopathology-proven aortitis. Read More

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http://dx.doi.org/10.1002/art.40855DOI Listing
February 2019
3 Reads

Pain Coping Skills Training for Patients Who Catastrophize About Pain Prior to Knee Arthroplasty: A Multisite Randomized Clinical Trial.

J Bone Joint Surg Am 2019 Feb;101(3):218-227

Department of Epidemiology and Biostatistics, Temple University, Philadelphia, Pennsylvania.

Background: Pain catastrophizing has been identified as a prognostic indicator of poor outcome following knee arthroplasty. Interventions to address pain catastrophizing, to our knowledge, have not been tested in patients undergoing knee arthroplasty. The purpose of this study was to determine whether pain coping skills training in persons with moderate to high pain catastrophizing undergoing knee arthroplasty improves outcomes 12 months postoperatively compared with usual care or arthritis education. Read More

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http://dx.doi.org/10.2106/JBJS.18.00621DOI Listing
February 2019
1 Read

Complementary and Alternative Medicine Use by U.S. Adults with Self-Reported Doctor-Diagnosed Arthritis: Results from the 2012 National Health Interview Survey.

PM R 2019 Feb 6. Epub 2019 Feb 6.

Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), Faculty of Health, University of Technology Sydney, Sydney, Australia.

Background: The use of complementary and alternative medicine (CAM) therapies have been reported for the management of arthritis. However, little is known about CAM use among adults with self-reported doctor-diagnosed (SRDD) arthritis since 2012.

Objectives: To determine: 1) the prevalence and type of CAM use, 2) the difference in characteristics between CAM users and non-CAM users, and 3) the factors related to CAM use, among US adults with SRDD arthritis. Read More

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http://dx.doi.org/10.1002/pmrj.12124DOI Listing
February 2019
1 Read

Impact of hepatitis C treatment on pain intensity, prescription opioid use and arthritis.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Oregon Health and Science University, Portland, Oregon.

Objective: To assess the impact of direct acting anti-viral (DAA) therapy for hepatitis C virus (HCV) infection on changes in pain intensity and prescription opioid use among Veterans.

Methods: We conducted a retrospective cohort study of Veterans with HCV who were seen in a rheumatology clinic at least once while receiving DAA therapy between January 1, 2010 and December 31st 2016. Demographic characteristics, HCV status, HCV treatment characteristics, numeric rating scale (NRS) pain scores and opioid prescription data were extracted from the electronic medical record. Read More

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http://dx.doi.org/10.1111/1756-185X.13479DOI Listing
February 2019
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Factors associated with physical activity engagement among adults with rheumatoid arthritis: A cross-sectional study.

Musculoskeletal Care 2019 Feb 6. Epub 2019 Feb 6.

Centre for Sports and Exercise Medicine, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Mile End Hospital, London, UK.

Objectives: Physical activity (PA) has a number of benefits for rheumatoid arthritis (RA) patients. However, these patients are more physically inactive than the general population. The primary aim of this study was to investigate factors associated with PA engagement among RA patients. Read More

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http://dx.doi.org/10.1002/msc.1385DOI Listing
February 2019
1 Read

Does weight loss reduce the severity and incidence of psoriasis or psoriatic arthritis? A critically-appraised topic.

Br J Dermatol 2019 Feb 6. Epub 2019 Feb 6.

St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Clinical Question: Does weight loss reduce the severity and incidence of psoriasis or psoriatic arthritis (PsA) in obese individuals?

Background: Obesity presents a rising public health challenge and is more prevalent amongst individuals with psoriasis or PsA compared to the general population. Longitudinal population-based studies suggest a causal role for obesity in psoriasis and PsA onset and that obesity drives greater disease severity.

Methods: We systematically reviewed evidence within Medline/EMBASE/CENTRAL databases and clinical trials registries examining lifestyle, pharmacological and surgical weight loss interventions in the treatment and prevention of psoriasis and PsA in obese individuals. Read More

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http://dx.doi.org/10.1111/bjd.17741DOI Listing
February 2019
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Inhibition of pSTAT1 by tofacitinib accounts for the early improvement of experimental chronic synovitis.

J Inflamm (Lond) 2019 29;16. Epub 2019 Jan 29.

1Bone and Joint Research Unit, Rheumatology Department, IIS-Fundación Jiménez Díaz UAM, Avenida Reyes Católicos, 2. 28040, Madrid, Spain.

Background: In order to gain insight into the early effects drawn by JAK inhibitors on intra-joint JAK/STAT-dependent signaling, we sought synovial activation of STATs and their end-products, along with their modification with tofacitinib (TOFA), at flare-up in antigen induced arthritis (AIA). New Zealand rabbits were randomly assigned to four groups -healthy controls, AIA, TOFA-treated AIA, or TOFA-treated controls-. AIA was induced with 4 weekly intra-articular ovalbumin injections in sensitized animals. Read More

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https://journal-inflammation.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s12950-019-0206-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352431PMC
January 2019
4 Reads

Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline.

BMJ 2019 Feb 6;364:l294. Epub 2019 Feb 6.

Department of Orthopaedic Surgery and Traumatology, Joint Research, OLVG, Amsterdam, The Netherlands

Clinical Question: Do adults with atraumatic shoulder pain for more than 3 months diagnosed as subacromial pain syndrome (SAPS), also labelled as rotator cuff disease, benefit from subacromial decompression surgery? This guideline builds on to two recent high quality trials of shoulder surgery.

Current Practice: SAPS is the common diagnosis for shoulder pain with several first line treatment options, including analgesia, exercises, and injections. Surgeons frequently perform arthroscopic subacromial decompression for prolonged symptoms, with guidelines providing conflicting recommendations. Read More

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http://dx.doi.org/10.1136/bmj.l294DOI Listing
February 2019
2 Reads

Cementless 3D Printed Highly Porous Titanium-Coated Baseplate Total Knee Arthroplasty: Survivorship and Outcomes at 2-Year Minimum Follow-Up.

J Knee Surg 2019 Feb 6. Epub 2019 Feb 6.

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.

Newer generation cementless total knee arthroplasty (TKA) implants continue to develop with demonstrated clinical success in multiple recent reports. The purpose of this study was to investigate (1) survivorship, (2) complications, and (3) clinical outcomes of a newer generation cementless and highly porous titanium-coated base plate manufactured using three-dimensional (3D) printing technology. We reviewed a single-surgeon, longitudinally maintained database of patients who underwent primary TKA using cementless, highly porous titanium-coated base plate implants from July 1, 2013 to December 31, 2016. Read More

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http://dx.doi.org/10.1055/s-0039-1677842DOI Listing
February 2019
2 Reads