Arthritis Care Res (Hoboken) 2023 Sep 26. Epub 2023 Sep 26.
Division of Dermatology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Introduction: The prevalence and types of psychosocial complications of juvenile localized scleroderma (JLS), also known as morphea, an inflammatory and sclerosing disease involving the skin, fascia, muscle, and bone are poorly understood.
Methods: We performed a systematic review of PUBMED, EMBASE, Cochrane Skin Group Specialized Register, Cochrane Central Register of Controlled Trials (CENTRAL), and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) between 2000 to 2020 using search terms: "scleroderma, localized" or "Morphea", "anxiety" or "depression" or "resilience" or "social stigma" or "quality of life" or "mood" or "stress" and limited to pediatric patients and English language. Patient demographics, characteristics of JLS, and comorbidities were extracted. Read More