125 results match your criteria Arthritis[Journal]


Diagnostic Performance of Red Cell Distribution Width in Adult Iraqi Patients with Ankylosing Spondylitis.

Arthritis 2018 5;2018:2904694. Epub 2018 Aug 5.

Baghdad Teaching Hospital, Rheumatology Unit, Baghdad, Iraq.

Background: Ankylosing spondylitis (AS) is a chronic, progressive inflammatory rheumatic disease that leads to structural damage, functional impairment, and decrease in the quality of life. Red cell distribution width (RDW) is a part of the complete blood count (CBC) and estimates erythrocyte variability.

Objective: To analyse RDW in patients with AS and to evaluate the relationships with acute phase reactants (APRs) and disease activity index. Read More

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https://www.hindawi.com/journals/arthritis/2018/2904694/
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http://dx.doi.org/10.1155/2018/2904694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098932PMC
August 2018
14 Reads

Burden of Depression among Working-Age Adults with Rheumatoid Arthritis.

Arthritis 2018 3;2018:8463632. Epub 2018 Jun 3.

School of Pharmacy, Department of Pharmaceutical Systems and Policy, West Virginia University, Morgantown, WV, USA.

Objective: This study estimated the excess clinical, humanistic, and economic burden associated with depression among working-age adults with Rheumatoid Arthritis (RA).

Methods: A retrospective cross-sectional study was conducted among working-age (18 to 64 years) RA patients with depression ( = 647) and without depression ( = 2,015) using data from the nationally representative Medical Expenditure Panel Survey for the years 2009, 2011, 2013, and 2015.

Results: Overall, 25. Read More

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http://dx.doi.org/10.1155/2018/8463632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008693PMC
June 2018
7 Reads

Physical Examination Tools Used to Identify Swollen and Tender Lower Limb Joints in Juvenile Idiopathic Arthritis: A Scoping Review.

Arthritis 2018 15;2018:3408162. Epub 2018 May 15.

School of Health Sciences, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW, Australia.

Background: Juvenile idiopathic arthritis (JIA) is the most common form of rheumatic disease in childhood and adolescents, affecting between 16 and 150 per 100,000 young persons below the age of 16. The lower limb is commonly affected in JIA, with joint swelling and tenderness often observed as a result of active synovitis.

Objective: The objective of this scoping review is to identify the existence of physical examination (PE) tools to identify and record swollen and tender lower limb joints in children with JIA. Read More

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http://dx.doi.org/10.1155/2018/3408162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976945PMC
May 2018
2 Reads

Education and Social Support as Key Factors in Osteoarthritis Management Programs: A Scoping Review.

Arthritis 2018 8;2018:2496190. Epub 2018 May 8.

Faculty of Health Sciences, University of Western Ontario, 1151 Richmond St., London, ON, Canada N6A 5B9.

Systematic reviews of self-management programs for osteoarthritis suggest minimal evidence of benefit and indicate substantial heterogeneity in interventions. The purpose of this scoping review was to describe the nature of self-management interventions provided to patients with osteoarthritis focusing on the inclusion and type of education and social support components. We searched PsycINFO, EMBASE, MEDLINE, and Cochrane Library databases from 1990 to 2016 to identify studies addressing community-based management strategies for osteoarthritis that included aspects of disease-specific education and ongoing social support. Read More

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http://dx.doi.org/10.1155/2018/2496190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964569PMC
May 2018
15 Reads

Biosimilars Have Arrived: Rituximab.

Arthritis 2018 22;2018:3762864. Epub 2018 Mar 22.

Biotechnology Clinical Development, Pfizer Inc., Cambridge, MA, USA.

A biosimilar is a biologic product that is highly similar to a licensed biologic ("originator") such that there are no clinically meaningful differences in safety, purity, or potency between the biosimilar and the originator. As patent protection and data exclusivity for the biologic rituximab expire, several potential biosimilars to rituximab are in development, which could soon lead to the availability of numerous rituximab biosimilars. Biosimilars are evaluated using thorough and rigorous analyses of the potential biosimilar versus the originator biological to confirm similar structure, function, and clinical efficacy as well as safety. Read More

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http://dx.doi.org/10.1155/2018/3762864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885398PMC
March 2018
6 Reads

Reliability and Construct Validity of the SENS Motion® Activity Measurement System as a Tool to Detect Sedentary Behaviour in Patients with Knee Osteoarthritis.

Arthritis 2018 1;2018:6596278. Epub 2018 Mar 1.

The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.

Physical inactivity is important to address, and an objective way of measuring inactivity is by accelerometry. The objective of this study was to determine the reliability and construct validity of the SENS motion system to record physical activity and inactivity in patients with knee osteoarthritis. Participants with an age > 40 years and an average weekly pain above 0 on a numeric rating scale (0 = no pain, 10 = worst pain) were included. Read More

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http://dx.doi.org/10.1155/2018/6596278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852870PMC
March 2018
1 Read

Confidence amongst Multidisciplinary Professionals in Managing Paediatric Rheumatic Disease in Australia.

Arthritis 2018 18;2018:7807490. Epub 2018 Jan 18.

School of Paediatrics and Child Health, The University of Sydney and Department of Rheumatology, The Sydney Children's Hospitals Network (Westmead and Randwick), Sydney, NSW, Australia.

Objective: Interprofessional collaboration is a crucial component of care for children with rheumatic disease. Interprofessional care, when delivered appropriately, prevents disability and improves long-term prognosis in this vulnerable group.

Methods: The aim of this survey was to explore allied health professionals' and nurses' confidence in treating paediatric rheumatology patients. Read More

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http://dx.doi.org/10.1155/2018/7807490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822930PMC
January 2018
1 Read

Healthcare Providers' Recommendations for Physical Activity among US Arthritis Population: A Cross-Sectional Analysis by Race/Ethnicity.

Arthritis 2018 4;2018:2807035. Epub 2018 Feb 4.

Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.

Introduction: We examined racial/ethnic disparities in healthcare providers' recommendations for physical activity among individuals with arthritis and evaluated this association among groups of individuals who adhered to physical activity guidelines and those who did not.

Methods: With a cross-sectional design based on Behavioral Risk Factor Surveillance System, we analyzed individuals with self-reported physician-diagnosed arthritis, ≥18 years of age ( = 83,376). Outcome variable was healthcare providers' recommendations for physical activity. Read More

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http://dx.doi.org/10.1155/2018/2807035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817278PMC
February 2018
3 Reads

Knee Fat Pad Volumes in Patients with Hemophilia and Their Relationship with Osteoarthritis.

Arthritis 2017 5;2017:1578623. Epub 2017 Dec 5.

Radiology Service, VA San Diego Healthcare System, San Diego, CA, USA.

Hemophilic arthropathy is a progressive, disabling condition with poorly understood pathobiology. Since there is an emerging interest to study the role of intra-articular fat pad size and biology in arthritic conditions, we explored fat pad volume changes in hemophilic arthropathy and to what extent they differed from osteoarthritis. We matched a cohort of 13 adult patients with hemophilic arthropathy of the knee with age- and gender-matched cohorts without osteoarthritis ("control cohort") and with the same degree of radiographic osteoarthritis ("OA cohort") in 1 : 2 fashion. Read More

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http://dx.doi.org/10.1155/2017/1578623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735625PMC
December 2017
1 Read

The Influence of Oblique Angle Forced Exercise in Surgically Destabilized Stifle Joints Is Synergistic with Bone, but Antagonistic with Cartilage in an Ovine Model of Osteoarthritis.

Arthritis 2017 27;2017:7481619. Epub 2017 Feb 27.

Department of Animal, Dairy and Veterinary Sciences, Center for Integrated BioSystems, School of Veterinary Medicine, Utah State University, Logan, UT, USA.

Large animal models of osteoarthritis are a necessary testing ground for FDA approval of human medicine applications. Sheep models have advantages over other available large animals, but development and progression of osteoarthritis in sheep is exceedingly slow, which handicaps progress in development of potential treatments. We combined oblique angle forced exercise to increase stress on the stifle, with surgical destabilization to hasten the development of osteoarthritis in ewes. Read More

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http://dx.doi.org/10.1155/2017/7481619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350401PMC
February 2017
6 Reads

Combination of Interleukin-27 and MicroRNA for Enhancing Expression of Anti-Inflammatory and Proosteogenic Genes.

Arthritis 2017 7;2017:6365857. Epub 2017 Feb 7.

Department of Basic Medical Sciences, Purdue University College of Veterinary Medicine, West Lafayette, IN 47907, USA.

Remission of inflammation has become an achievable goal in inflammatory or rheumatoid arthritis (RA); however, bone erosion continues in many patients. Interleukin- (IL-) 27 regulates immune and bone cell balance and also suppresses activities of several inflammatory cell types in RA. Despite its promise, challenges to clinical translation of IL-27 have been its partial effects . Read More

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http://dx.doi.org/10.1155/2017/6365857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318630PMC
February 2017
1 Read

Infrapatellar Fat Pad: An Alternative Source of Adipose-Derived Mesenchymal Stem Cells.

Arthritis 2016 26;2016:4019873. Epub 2016 Apr 26.

Department of Orthopaedics, Faculty of Medicine, Ramathibodi Hospital, Bangkok 10400, Thailand.

Introduction. The Infrapatellar fat pad (IPFP) represents an emerging alternative source of adipose-derived mesenchymal stem cells (ASCs). We compared the characteristics and differentiation capacity of ASCs isolated from IPFP and SC. Read More

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http://dx.doi.org/10.1155/2016/4019873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861778PMC
May 2016
1 Read

Towards Tailored Patient's Management Approach: Integrating the Modified 2010 ACR Criteria for Fibromyalgia in Multidimensional Patient Reported Outcome Measures Questionnaire.

Arthritis 2016 13;2016:5371682. Epub 2016 Apr 13.

Internal Medicine, Cairo University, Cairo, Egypt.

Objectives. To assess the validity, reliability, and responsiveness to change of a patient self-reported questionnaire combining the Widespread Pain Index and the Symptom Severity Score as well as construct outcome measures and comorbidities assessment in fibromyalgia patients. Methods. Read More

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http://dx.doi.org/10.1155/2016/5371682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846760PMC

Amtolmetin: A Reappraisal of NSAID with Gastroprotection.

Arthritis 2016 22;2016:7103705. Epub 2016 Mar 22.

Global Medical Affairs, Dr. Reddy's Laboratories Ltd., Hyderabad 500034, India.

Aim. To assess the gastrosparing effect of amtolmetin guacyl (AMG) against other nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with osteo-/rheumatoid arthritis. Methods. Read More

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http://dx.doi.org/10.1155/2016/7103705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820613PMC
April 2016
5 Reads

RNA Interference Mediated Interleukin-1β Silencing in Inflamed Chondrocytes Decreases Target and Downstream Catabolic Responses.

Arthritis 2016 17;2016:3484961. Epub 2016 Mar 17.

Department of Clinical Sciences, Cornell University, Ithaca, NY 14853, USA.

Posttraumatic activation of the catabolic cascade plays a major role in degradation of cartilage. Interleukin-1β (IL-1β), a primary instigator in the catabolic axis, is upregulated in chondrocytes following injury. IL-1β activates key degradative enzymes, including MMPs and aggrecanases, and other proinflammatory mediators such as PGE2 which contribute to ECM breakdown. Read More

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https://www.hindawi.com/archive/2016/3484961/
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http://dx.doi.org/10.1155/2016/3484961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814636PMC
April 2016
2 Reads

Establishing the Psychometric Properties of the ICOAP Questionnaire through Intra-Articular Treatment of Osteoarthritic Pain: Implementation for the Greek Version.

Arthritis 2016 13;2016:6201802. Epub 2016 Mar 13.

Faculty of Social Sciences, Hellenic Open University, Patras, Greece.

Objectives. In this prospective study, we intend to establish the psychometric properties of ICOAP for its use in studies involving the Hellenic population. Methods. Read More

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http://dx.doi.org/10.1155/2016/6201802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808562PMC
April 2016
34 Reads

The Combination of the Tunnel View and Weight-Bearing Anteroposterior Radiographs Improves the Detection of Knee Arthritis.

Arthritis 2016 26;2016:9786924. Epub 2016 Jan 26.

Center for Hip and Knee Replacement (CHKR), Department of Orthopaedic Surgery, NewYork-Presbyterian Hospital, Columbia University Medical Center, 622 W. 168th Street, PH 1155, New York, NY 10032, USA.

Imaging used for the evaluation of knee pain has historically included weight-bearing anteroposterior (AP), lateral, and sunrise radiographs. We wished to evaluate the utility of adding the weight-bearing (WB) posteroanterior (PA) view of the knee in flexion. We hypothesize that (1) the WB tunnel view can detect radiographic osteoarthritis (OA) not visualized on the WB AP, (2) the combination of the AP and tunnel view increases the radiographic detection of OA, and (3) this may provide additional information to the clinician evaluating knee pain. Read More

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http://dx.doi.org/10.1155/2016/9786924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746274PMC
February 2016
9 Reads

The Interchangeability of Plasma and Whole Blood Metal Ion Measurement in the Monitoring of Metal on Metal Hips.

Arthritis 2015 20;2015:216785. Epub 2015 Dec 20.

University Hospital of Wales, Heath Park, Cardiff CF14 4XW, UK.

One hundred and twenty six paired samples of plasma and whole blood were measured with inductively coupled plasma mass spectrometry technique for metal ions analysis to determine a relationship between them. There was a significant difference between the mean plasma and whole blood concentrations of both cobalt (Co) and chromium (Cr) (p < 0.0001 for both Co and Cr). Read More

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http://dx.doi.org/10.1155/2015/216785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699225PMC
January 2016
1 Read

Sucupira as a Potential Plant for Arthritis Treatment and Other Diseases.

Arthritis 2015 3;2015:379459. Epub 2015 Nov 3.

Postgraduate Program in Pharmaceutical Sciences, State University of Maringá, Avenida Colombo 5790, 87020-900 Maringá, PR, Brazil.

Trees of the genus Pterodon, commonly known as "sucupira-branca" or "faveira," are native to central Brazil. The Pterodon fruits are traditionally used in ethnomedicine as an infusion, in small doses, and at regular time intervals as an antirheumatic, anti-inflammatory, tonic, and depurative agent. The various compounds present in the Pterodon class are, generally, water-insoluble and derived from the fusion of high-molecular weight pentacarbonate units. Read More

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http://dx.doi.org/10.1155/2015/379459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646998PMC
November 2015
13 Reads

A Systematic Review Investigating the Presence of Inflammatory Synovitis in Hip and Knee Joint Replacement Surgery.

Arthritis 2015 18;2015:729410. Epub 2015 Oct 18.

South West London Elective Orthopaedic Centre, Dorking Road, Epsom, Surrey KT18 7EG, UK ; St George's, University of London, Cranmer Terrace, London SW17 0RE, UK ; Epsom & St Helier NHS Trust, UK.

Synovial tissue can display an inflammatory response in the presence of OA. There is increasing interest to better understand the role of inflammation in OA, particularly with regard to those who require joint replacement. A systematic review of inflammatory synovitis in OA of literature databases was undertaken from their inception until October 14, 2014. Read More

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http://dx.doi.org/10.1155/2015/729410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628772PMC
November 2015
13 Reads

Relationship between Tibial Baseplate Design and Rotational Alignment Landmarks in Primary Total Knee Arthroplasty.

Arthritis 2015 28;2015:189294. Epub 2015 Sep 28.

Clinica Ortopedica, Universita degli Studi di Firenze, CESAT, 50054 Fucecchio, Italy.

This study evaluated the influence of modern tibial baseplate designs when using the anterior tibial cortex as a primary rotational landmark for the tibial baseplate in TKA. Eighty patients undergoing TKA were randomized in two groups. Group 1 included 25 females and 15 males receiving a posterior-stabilized (PS) symmetric tibial baseplate while Group 2 included 24 females and 16 males receiving a PS anatomical tibial component. Read More

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http://www.hindawi.com/journals/arthritis/2015/189294/
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http://dx.doi.org/10.1155/2015/189294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600913PMC
October 2015
1 Read

Role of Health Literacy in Self-Reported Musculoskeletal Disorders.

Arthritis 2015 18;2015:607472. Epub 2015 Aug 18.

Population Research & Outcomes Unit, University of Adelaide, Adelaide, SA 5005, Australia.

Self-report of musculoskeletal conditions is often used to estimate population prevalence and to determine disease burden and influence policy. However, self-report of certain musculoskeletal conditions is frequently inaccurate, suggesting inadequate communication to the patient of their diagnosis. The aim of this study is to determine the association between functional health literacy (FHL) and self-reported musculoskeletal conditions in a representative population survey. Read More

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http://dx.doi.org/10.1155/2015/607472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556058PMC
September 2015
5 Reads

Screening Optimization of Latent Tuberculosis Infection in Rheumatoid Arthritis Patients.

Arthritis 2015 29;2015:569620. Epub 2015 Jul 29.

Rheumatology Division, New York Methodist Hospital, Weill Cornell Medical College, New York, NY 11215, USA.

Objective. Rheumatoid arthritis (RA) patients are at increased risk of latent tuberculosis infection (LTBI) but there are no clear guidelines for LTBI screening with Tuberculin Skin Test (TST) or Quantiferon TB Gold testing (QFT-G). Methods. Read More

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http://dx.doi.org/10.1155/2015/569620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532802PMC
August 2015
22 Reads

Pain Sensitisation in Women with Active Rheumatoid Arthritis: A Comparative Cross-Sectional Study.

Arthritis 2015 21;2015:434109. Epub 2015 Jul 21.

The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, 2000 Frederiksberg, Denmark ; The Health Science Faculty, University of Copenhagen, 2200 Copenhagen N, Denmark.

Objectives. In some rheumatoid arthritis (RA) patients, joint pain persists without signs of inflammation. This indicates that central pain sensitisation may play a role in the generation of chronic pain in a subgroup of RA. Read More

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http://dx.doi.org/10.1155/2015/434109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523644PMC
August 2015
15 Reads

Depression and the Overall Burden of Painful Joints: An Examination among Individuals Undergoing Hip and Knee Replacement for Osteoarthritis.

Arthritis 2015 11;2015:327161. Epub 2015 Mar 11.

Division of Orthopaedic Surgery, Toronto Western Hospital, University of Toronto, 399 Bathurst Street 1E449, Toronto, ON, Canada M5T 2S8 ; Institute of Health Policy, Management & Evaluation, University of Toronto, Toronto, ON, Canada.

The majority of patients with hip or knee osteoarthritis (OA) report one or more symptomatic joints apart from the one targeted for surgical care. Therefore, the purpose of the present study was to investigate the association between the burden of multiple symptomatic joints and self-reported depression in patients awaiting joint replacement for OA. Four hundred and seventy-five patients at a single centre were evaluated. Read More

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http://dx.doi.org/10.1155/2015/327161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377445PMC
April 2015
2 Reads

Whole-foods, plant-based diet alleviates the symptoms of osteoarthritis.

Arthritis 2015 28;2015:708152. Epub 2015 Feb 28.

Department of Internal Medicine, Michigan State University College of Human Medicine, 15 Michigan Street NE, Grand Rapids, MI 49503, USA.

Objective. To evaluate the effectiveness of a whole-foods, plant-based diet (WFPB) to reduce symptoms of osteoarthritis. Methods. Read More

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http://dx.doi.org/10.1155/2015/708152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359818PMC
March 2015
5 Reads

Adherence to methotrexate in rheumatoid arthritis: a danish nationwide cohort study.

Arthritis 2015 25;2015:915142. Epub 2015 Feb 25.

Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark.

Objectives. To study adherence to methotrexate (MTX) and factors of importance thereof in patients with rheumatoid arthritis (RA). Methods. Read More

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http://dx.doi.org/10.1155/2015/915142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355606PMC
March 2015
13 Reads

The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial.

Arthritis 2015 31;2015:251521. Epub 2015 Jan 31.

Atrium Innovations, 4 Hillman Drive, Suite 190, Chadds Ford, PA 19317, USA.

This randomized, double-blind, placebo-controlled, and comparator-controlled trial evaluated the safety and efficacy of an enzyme combination, as Wobenzym, in adults with moderate-to-severe osteoarthritis (OA) of the knee. Adults (n = 150) received Wobenzym, diclofenac (a nonsteroidal anti-inflammatory drug, NSAID), or placebo for 12 weeks. Improvement in pain scores (Lequesne Functional Index) did not differ between subjects treated with Wobenzym or diclofenac, and both treatment groups improved compared to placebo (P < 0. Read More

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http://dx.doi.org/10.1155/2015/251521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329848PMC
March 2015
6 Reads

Early metacarpal bone mineral density loss using digital x-ray radiogrammetry and 3-tesla wrist MRI in established rheumatoid arthritis: a longitudinal one-year observational study.

Arthritis 2015 17;2015:852989. Epub 2015 Feb 17.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK.

Objectives. Early change in rheumatoid arthritis (RA) is characterised by periarticular osteopenia. We investigated the relationship of early metacarpal digital X-ray radiogrammetry bone mineral density (DXR-BMD) change rate (RC-BMD, mg/cm(2)/month) to longitudinal changes in hand and feet radiographic and wrist MRI scores over 1 year. Read More

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http://dx.doi.org/10.1155/2015/852989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346684PMC
March 2015
10 Reads

Antibodies to infliximab and adalimumab in patients with rheumatoid arthritis in clinical remission: a cross-sectional study.

Arthritis 2015 11;2015:784825. Epub 2015 Feb 11.

Department of Clinical Biochemistry, Copenhagen University Hospital at Køge, 4600 Køge, Denmark.

Objective. To investigate if antibodies towards biological TNF-α inhibitors (anti-TNFi Abs) are present in patients with rheumatoid arthritis (RA) in clinical remission and to relate any anti-TNFi Abs to circulating level of TNF-α inhibitor (TNFi). Methods. Read More

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http://dx.doi.org/10.1155/2015/784825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339793PMC
March 2015
20 Reads

Validity and Agreement between the 28-Joint Disease Activity Score Based on C-Reactive Protein and Erythrocyte Sedimentation Rate in Patients with Rheumatoid Arthritis.

Arthritis 2015 14;2015:401690. Epub 2015 Jan 14.

The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, 2000 Frederiksberg, Denmark.

Objective. To validate the agreement between the 28-joint disease activity score based on erythrocyte sedimentation rate (DAS28-ESR) and the 28-joint disease activity score based on C-reactive protein (DAS28-CRP) in a group of Danish patients with rheumatoid arthritis (RA). Methods. Read More

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http://downloads.hindawi.com/journals/arthritis/2015/401690.
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http://www.hindawi.com/journals/arthritis/2015/401690/
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http://dx.doi.org/10.1155/2015/401690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303021PMC
January 2015
52 Reads

Epicardial fat thickness as cardiovascular risk factor and therapeutic target in patients with rheumatoid arthritis treated with biological and nonbiological therapies.

Arthritis 2014 10;2014:782850. Epub 2014 Dec 10.

Division of Endocrinology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with high cardiovascular morbidity and mortality. Epicardial adipose tissue (EAT) thickness may act as a therapeutic target during treatments with drugs modulating the adipose tissue. We evaluate EAT thickness in RA patients treated with biological and nonbiological disease-modifying antirheumatic drugs (DMARDs). Read More

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http://dx.doi.org/10.1155/2014/782850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276696PMC
January 2015
5 Reads

Progression of Gene Expression Changes following a Mechanical Injury to Articular Cartilage as a Model of Early Stage Osteoarthritis.

Arthritis 2014 16;2014:371426. Epub 2014 Nov 16.

Joint Department of Biomedical Engineering, North Carolina State University, Raleigh, NC 27695, USA ; University of North Carolina, Chapel Hill, NC 27599, USA.

An impact injury model of early stage osteoarthritis (OA) progression was developed using a mechanical insult to an articular cartilage surface to evaluate differential gene expression changes over time and treatment. Porcine patellae with intact cartilage surfaces were randomized to one of three treatments: nonimpacted control, axial impaction (2000 N), or a shear impaction (500 N axial, with tangential displacement to induce shear forces). After impact, the patellae were returned to culture for 0, 3, 7, or 14 days. Read More

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http://dx.doi.org/10.1155/2014/371426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248372PMC
December 2014

Evaluation of Antiarthritic Potential of Methanolic Extract of Gentiana kurroo Royle.

Arthritis 2014 6;2014:810615. Epub 2014 Nov 6.

Regional Research Institute of Unani Medicine, Kashmir University Campus, Srinagar 190006, India.

Rheumatoid arthritis is a systemic disorder which involves the activation of immune system against the self-tissues. The main targets of this disease are the joints. Being systemic the development of this disease involves different mechanisms and thus the exact cause of this disease remains unknown. Read More

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http://dx.doi.org/10.1155/2014/810615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241291PMC
November 2014
3 Reads

Short Term Recovery of Function following Total Knee Arthroplasty: A Randomised Study of the Medial Parapatellar and Midvastus Approaches.

Arthritis 2014 1;2014:173857. Epub 2014 Oct 1.

Rehabilitation Sciences, Queen Margaret University, Queen Margaret University Drive, Musselburgh EH21 6UU, UK.

This pilot double blind randomised controlled study aimed to investigate whether the midvastus (MV) approach without patellar eversion in total knee arthroplasty (TKA) resulted in improved recovery of function compared to the medial parapatellar (MP) approach. Patients were randomly allocated to either the MV approach or the MP approach. Achievements of inpatient mobility milestones were recorded. Read More

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http://dx.doi.org/10.1155/2014/173857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198781PMC
October 2014
2 Reads

Psychometric properties of the 8-item english arthritis self-efficacy scale in a diverse sample.

Arthritis 2014 21;2014:385256. Epub 2014 Aug 21.

Prevention Research Center and Department of Exercise Science, Arnold School of Public Health, University of South Carolina, 921 Assembly Street, Columbia, SC 29208, USA.

Arthritis self-efficacy is important for successful disease management. This study examined psychometric properties of the 8-item English version of the Arthritis Self-Efficacy Scale (ASES-8) and differences in ASES-8 scores across sample subgroups. In 401 participants with self-reported doctor-diagnosed arthritis, exploratory factor analysis and tests of internal consistency were conducted. Read More

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http://dx.doi.org/10.1155/2014/385256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158258PMC
September 2014

Individual and community socioeconomic status: impact on mental health in individuals with arthritis.

Arthritis 2014 4;2014:256498. Epub 2014 Aug 4.

Departments of Medicine and Social Medicine, Thurston Arthritis Research Center, Department of Epidemiology, Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

To examine the impact of individual and community socioeconomic status (SES) measures on mental health outcomes in individuals with arthritis, participants with self-reported arthritis completed a telephone survey assessing health status, health attitudes and beliefs, and sociodemographic variables. Regression analyses adjusting for race, gender, BMI, comorbidities, and age were performed to determine the impact of individual and community level SES on mental health outcomes (i.e. Read More

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http://dx.doi.org/10.1155/2014/256498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137496PMC

Zingiber officinale: A Potential Plant against Rheumatoid Arthritis.

Arthritis 2014 27;2014:159089. Epub 2014 May 27.

Department of Pharmacy, University of Development Alternative, Dhanmondi, Dhaka 1209, Bangladesh.

Rheumatoid arthritis (RA) is an autoimmune disease particularly affecting elderly people which leads to massive bone destruction with consequent inflammation, pain, and debility. Allopathic medicine can provide only symptomatic relief. However, Zingiber officinale is a plant belonging to the Zingiberaceae family, which has traditionally been used for treatment of RA in alternative medicines of many countries. Read More

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http://dx.doi.org/10.1155/2014/159089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058601PMC

Fibroblast-like synoviocytes induce calcium mineral formation and deposition.

Arthritis 2014 20;2014:812678. Epub 2014 May 20.

Department of Orthopedic Surgery, Carolinas Medical Center, P.O. Box 32861, Charlotte, NC 28232, USA.

Calcium crystals are present in the synovial fluid of 65%-100% patients with osteoarthritis (OA) and 20%-39% patients with rheumatoid arthritis (RA). This study sought to investigate the role of fibroblast-like synoviocytes (FLSs) in calcium mineral formation. We found that numerous genes classified in the biomineral formation process, including bone gamma-carboxyglutamate (gla) protein/osteocalcin, runt-related transcription factor 2, ankylosis progressive homolog, and parathyroid hormone-like hormone, were differentially expressed in the OA and RA FLSs. Read More

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http://dx.doi.org/10.1155/2014/812678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054973PMC
June 2014
2 Reads

Quantitative Gait Analysis Detects Significant Differences in Movement between Osteoarthritic and Nonosteoarthritic Guinea Pig Strains before and after Treatment with Flunixin Meglumine.

Arthritis 2014 19;2014:503519. Epub 2014 May 19.

Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210, USA ; Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH 43210, USA.

A computer-aided gait analysis system was used to contrast two guinea pig strains with differing propensity for osteoarthritis (OA), with/without administration of a nonsteroidal anti-inflammatory drug. Walking speed and static/dynamic gait parameters were determined at baseline. Flunixin meglumine was given and animals were evaluated 4, 24, and 72 hours after treatment. Read More

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http://dx.doi.org/10.1155/2014/503519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055278PMC

Weight status and differences in mobility performance, pain symptoms, and physical activity in older, knee osteoarthritis patients.

Arthritis 2014 25;2014:375909. Epub 2014 May 25.

Health and Exercise Science Department, Wake Forest University, P.O. Box 7868, Winston-Salem, NC 27109, USA.

Knee osteoarthritis (OA) is a leading cause of functional disability among American adults. Obesity is a strong independent risk factor for OA. While research emphasizes the role of obesity in the OA-physical function relationship, the extent to which weight status impacts salient physical, health, and pain measures in older, knee OA patients is not well delineated. Read More

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http://www.hindawi.com/journals/arthritis/2014/375909/
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http://dx.doi.org/10.1155/2014/375909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055557PMC
June 2014
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Treatment of nongout joint deposition diseases: an update.

Arthritis 2014 8;2014:375202. Epub 2014 May 8.

Department of Rheumatology, Roger Salengro Hospital, Lille 2 University, rue Emile Laine, 59037 Lille Cedex, France.

This update develops the actual therapeutic options in the management of the joint involvement of calcium pyrophosphate deposition disease (CPPD), basic calcium phosphate (BCP) deposition disease, hemochromatosis (HH), ochronosis, oxalosis, and Wilson's disease. Conventional pharmaceutical treatment provides benefits for most diseases. Anti-interleukine-1 (IL-1) treatment could provide similar results in CPPD than in gout flares. Read More

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http://dx.doi.org/10.1155/2014/375202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034491PMC
June 2014
11 Reads

Productivity improvements in hip and knee surgery.

Arthritis 2014 20;2014:615784. Epub 2014 Feb 20.

Center for the Study of Aging, Duke University Medical Center, P.O. Box 3003, Durham, NC 27710, USA.

Productivity improvements that occur as technologies become widely used are not well documented. This study measured secular trends over 1998-2010 in productivity of hip and knee procedures gauged in terms of changes in physical function and pain after versus before surgery. We used data from the Health and Retirement Study. Read More

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http://dx.doi.org/10.1155/2014/615784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950645PMC
April 2014
2 Reads

Glucosamine for osteoarthritis: biological effects, clinical efficacy, and safety on glucose metabolism.

Arthritis 2014 11;2014:432463. Epub 2014 Feb 11.

Endocrine and Metabolic Diseases Research Center, Faculty of Medicine, University of Zulia, Maracaibo 4004, Venezuela.

Osteoarthritis is a chronic degenerative disorder that currently represents one of the main causes of disability within the elderly population and an important presenting complaint overall. The pathophysiologic basis of osteoarthritis entails a complex group of interactions among biochemical and mechanical factors that have been better characterized in light of a recent spike in research on the subject. This has led to an ongoing search for ideal therapeutic management schemes for these patients, where glucosamine is one of the most frequently used alternatives worldwide due to their chondroprotective properties and their long-term effects. Read More

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http://dx.doi.org/10.1155/2014/432463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941227PMC
June 2014
30 Reads

A technique of predicting radiographic joint line and posterior femoral condylar offset of the knee.

Arthritis 2014 11;2014:121069. Epub 2014 Feb 11.

Department of Orthopaedics and Trauma, The Royal Infirmary of Edinburgh, Little France, Edinburgh EH16 4SA, UK.

Purpose. To describe a reliable method of predicting native joint line and posterior condylar offset (PCO) using true lateral digital radiographs of the distal femur. Methods. Read More

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https://www.hindawi.com/archive/2014/121069/
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http://dx.doi.org/10.1155/2014/121069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942290PMC
March 2014
5 Reads

Application of a Simple In-House PCR-SSP Technique for HLA-B* 27 Typing in Spondyloarthritis Patients.

Arthritis 2013 19;2013:504109. Epub 2013 Dec 19.

National Institute of Immunohematology, 13th Floor, NMS Building, King Edward Memorial Hospital Campus, Parel, Mumbai, Maharashtra 400012, India.

Background. Microlymphocytotoxicity (MLCT) and flowcytometry (FC) are the conventional serological methods to detect HLA-B* 27. Due to some disadvantages in these methods, most of the HLA laboratories have now switched over to molecular methods. Read More

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http://dx.doi.org/10.1155/2013/504109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880732PMC
February 2014
1 Read

The good life: assessing the relative importance of physical, psychological, and self-efficacy statuses on quality of well-being in osteoarthritis patients.

Arthritis 2013 25;2013:914216. Epub 2013 Dec 25.

San Diego State University, 6505 Alvarado Road, Suite 110, San Diego, CA 92120, USA ; San Diego State University and University of California, Joint Doctoral Program in Clinical Psychology, San Diego, CA 92120, USA.

Background and Purpose. The purpose of the present study was to examine the interrelationships among physical dysfunction, self-efficacy, psychological distress, exercise, and quality of well-being for people with osteoarthritis. It was predicted that exercise would mediate the relationships between physical dysfunction, self-efficacy, psychological distress, and quality of well-being. Read More

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http://dx.doi.org/10.1155/2013/914216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886609PMC
January 2014
7 Reads

Capillaroscopy in psoriatic and rheumatoid arthritis: a useful tool for differential diagnosis.

Arthritis 2013 12;2013:957480. Epub 2013 Dec 12.

San Gallicano Dermatological Institute, Rome, Italy.

Impairment of capillaries permeability and changes of microcirculation are associated with inflammatory arthritis. In order to demonstrate microvascular differences between psoriatic arthritis (PsA) and rheumatoid arthritis (RA) we analyzed capillaroscopic abnormalities such as megacapillaries, haemorrhages, ramifications, and avascular areas in patients affected by these two rheumatic disorders. Moreover to identify specific capillaroscopy patterns we analyzed the following parameters: venous limb diameter, arterial limb diameter, capillary loop diameter, amplitude of the capillary loop, linear density of capillaries (on 2 mm), and number of twisted capillaries (on 4 mm). Read More

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http://dx.doi.org/10.1155/2013/957480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874353PMC
January 2014
8 Reads

Association of body mass index with physical function and health-related quality of life in adults with arthritis.

Arthritis 2013 12;2013:190868. Epub 2013 Dec 12.

Prevention Research Center, Arnold School of Public Health, University of South Carolina, 1st Floor, 921 Assembly Street, Columbia, SC 29208, USA ; Department of Health Science, Saginaw Valley State University, 7400 Bay Road University Center, MI 48710, USA.

Arthritis and obesity, both highly prevalent, contribute greatly to the burden of disability in US adults. We examined whether body mass index (BMI) was associated with physical function and health-related quality of life (HRQOL) measures among adults with arthritis and other rheumatic conditions. We assessed objectively measured BMI and physical functioning (six-minute walk, chair stand, seated reach, walking velocity, hand grip) and self-reported HRQOL (depression, stiffness, pain, fatigue, disability, quality of life-mental, and quality of life, physical) were assessed. Read More

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http://dx.doi.org/10.1155/2013/190868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874331PMC
January 2014
1 Read