Search Our Scientific Publications & Authors

Handchir Mikrochir Plast Chir 2020 May 28. Epub 2020 May 28.

AGAPLESION MARKUS KRANKENHAUS, Akademisches Lehrkrankenhaus der Johann Wolfgang Goethe-Universität Frankfurt am Main, Klinik für Plastische, Ästhetische, Wiederherstellungs- und Handchirurgie.

Background:  Anomalies of the radial arterial system can be of importance during harvesting of a radial forearm flap. In particular when using the forearm flap for phalloplasty due to the required dimensions of the flap, sufficient arterial supply is of fundamental importance. In case of a persistent median artery perfusion conditions in the supply area of ​​the A. Read More

Hand Clin 2020 Feb;36(1):1-8

Department of Hand and Reconstructive Microsurgery, National University Health System, Level 11, Tower Block 1E Kent Ridge Road, Singapore 119228, Singapore. Electronic address:

The vascular supply of the hand and wrist is derived from the radial and ulnar arteries. This forms a complex network of vessels on the palmar and dorsal surfaces of the hand. Anastomoses and branching patterns of vessels at the level of the carpals, metacarpals, and phalanges form the basis of old and new flap designs. Read More

Handb Clin Neurol 2019 ;166:3-21

Cingulum Neurosciences Institute, Manlius, NY, United States; Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, United States.

A brief review of the history of key observations of cingulate organization, particularly in the limbic system framework, is presented from 1907 to the present. The reasons why it has not played a significant role in neurology reflect the fact that its arterial supply is complex and no cingulate syndrome has been identified. A flat map of its eight subregions and areas is presented as a basis for many subsequent chapters in this volume. Read More

Surg Today 2020 Jan 16;50(1):38-49. Epub 2019 Oct 16.

Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Visceral artery aneurysms (VAAs) are rare and affect the celiac artery, superior mesenteric artery, and inferior mesenteric artery, and their branches. The natural history of VAAs is not well understood as they are often asymptomatic and found incidentally; however, they carry a risk of rupture that can result in death from hemorrhage in the peritoneal cavity, retroperitoneal space, or gastrointestinal tract. Recent advances in imaging technology and its availability allow us to diagnose all types of VAA. Read More

Arch Esp Urol 2019 10;72(8):723-728

ORSI Academy. Melle. Belgium. Department of Urology. Onze Lieve Vrouw Hospital. Aalst. Belgium.

The trend towards the organ sparing and robotic assisted surgeries is clear and is going to expand in the future. Hence, the tools surgeons need to facilitate such minimallly invasive approaches are going to be even more important. The Indocyanine green (ICG) is a water-soluble, relatively hydrophobic dye which bounds to plasma protein and can be used intraoperatively as real time contrast agent. Read More

Eur J Obstet Gynecol Reprod Biol 2019 Nov 23;242:47-55. Epub 2019 Aug 23.

Gynecological Oncology Unit, Department of Obstetrics and Gynecology, Multidisciplinary Breast Clinic, Antwerp University Hospital, University of Antwerp, Wilrijkstraat 10, B-2650, Antwerp, Belgium.

In the industrialised world still 34% of the breast cancer patients are surgically treated by a mastectomy. Breast cancer patients in general have a good prognosis and a long-term survival. Therefore, it is important that the treatment doesn't focus only on survival but also on the quality of life. Read More

Reproduction 2019 Aug 1. Epub 2019 Aug 1.

M Ribeiro, Laboratorio de Fisiología y Farmacología de la Reproducción, CEFYBO (CONICET, UBA), Buenos Aires, Argentina.

Lysophosphatidic acid (LPA) belongs to the group of phosphorylated lipids reported as crucial mediators in the physiology of reproduction. LPA binds to G-protein coupled receptors and regulates a wide range of female reproductive functions. This bioactive lipid has been also implicated in vascular functions during physiological and pathological conditions. Read More

Crit Care 2019 Jul 30;23(1):266. Epub 2019 Jul 30.

Department of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Cardiovascular Research Institute (CARIM), Maastricht University, Maastricht, The Netherlands.

Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is an increasingly adopted life-saving mechanical circulatory support for a number of potentially reversible or treatable cardiac diseases. It is also started as a bridge-to-transplantation/ventricular assist device in the case of unrecoverable cardiac or cardio-respiratory illness. In recent years, principally for non-post-cardiotomy shock, peripheral cannulation using the femoral vessels has been the approach of choice because it does not need the chest opening, can be quickly established, can be applied percutaneously, and is less likely to cause bleeding and infections than central cannulation. Read More

Int J Mol Sci 2019 Jul 29;20(15). Epub 2019 Jul 29.

Department of Surgery, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

Mouse hind limb ischemia is the most common used preclinical model for peripheral arterial disease and critical limb ischemia. This model is used to investigate the mechanisms of neovascularization and to develop new therapeutic agents. The literature shows many variations in the model, including the method of occlusion, the number of occlusions, and the position at which the occlusions are made to induce hind limb ischemia. Read More

Radiographics 2019 Sep-Oct;39(5):1526-1548. Epub 2019 Jul 26.

From the Departments of Radiology (A.C.P., A.M.V.) and Urology (T.C.H., R.M.S.), University of California San Diego, San Diego, Calif, and Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, NC (A.J.I.).

Symptomatic benign prostatic hyperplasia is a common condition in the aging population that results in bothersome lower urinary tract symptoms and decreased quality of life. Patients often are treated with medication and offered surgery for persistent symptoms. Transurethral resection of the prostate is considered the traditional standard of care, but several minimally invasive surgical treatments also are offered. Read More

World Neurosurg 2019 Oct 11;130:e941-e952. Epub 2019 Jul 11.

Department of Neurosurgery, The Permanente Medical Group, Kaiser Sacramento Medical Center, Sacramento, California, USA.

Background: Poorly understood cranial fluid accumulations are frequently observed after decompressive craniectomy and often termed "external hydrocephalus." These findings are difficult to explain using traditional models of hydrocephalus.

Methods: Representative cases, clinical management, and literature overview are presented. Read More

Ceska Gynekol 2019 ;84(2):149-153

Objective: To review contemporary knowledge of isolated vasculitis in urology and gynaecology.

Design: A review.

Setting: Department of Obstetrics and Gynaecology, University Hospital Hradec Kralove. Read More

J Stroke Cerebrovasc Dis 2019 Aug 31;28(8):2098-2108. Epub 2019 May 31.

Neurology Section, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Sneddon syndrome (SS) is an episodic or chronic, slowly progressive disorder and characterized by generalized livedo racemosa (patchy, violaceous, skin discoloration) and recurrent cerebrovascular events. The histopathology of skin and brain is remarkable for a noninflammatory thrombotic vasculopathy involving medium- and small-sized dermal and cerebral arteries, respectively. Approximately 80% of the SS patients are women with a median age of diagnosis at 40 years. Read More

J Stroke Cerebrovasc Dis 2019 Aug 28;28(8):2079-2097. Epub 2019 May 28.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

Since the term "lacune" was adopted in the 1800s to describe infarctions from cerebral small vessels, their underlying pathophysiological basis remained obscure until the 1960s when Charles Miller Fisher performed several autopsy studies of stroke patients. He observed that the vessels displayed segmental arteriolar disorganization that was associated with vessel enlargement, hemorrhage, and fibrinoid deposition. He coined the term "lipohyalinosis" to describe the microvascular mechanism that engenders small subcortical infarcts in the absence of a compelling embolic source. Read More

United European Gastroenterol J 2019 03 4;7(2):179-188. Epub 2018 Dec 4.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.

This Ron Balm, Academic Medical Center, Amsterdam Gert Jan de Borst, University Medical Center Utrecht, Utrecht Juliette T Blauw, Medisch Spectrum Twente, Enschede Marco J Bruno, Erasmus MC University Medical Center, Rotterdam Olaf J Bakker, St Antonius Hospital, Nieuwegein Louisa JD van Dijk, Erasmus MC University Medical Center, Rotterdam Hessel CJL Buscher, Gelre Hospitals, Apeldoorn Bram Fioole, Maasstad Hospital, Rotterdam Robert H Geelkerken, Medisch Spectrum Twente, Enschede Jaap F Hamming, Leiden University Medical Center, Leiden Jihan Harki, Erasmus MC University Medical Center, Rotterdam Daniel AF van den Heuvel, St Antonius Hospital, Nieuwegein Eline S van Hattum, University Medical Center Utrecht, Utrecht Jan Willem Hinnen, Jeroen Bosch Hospital, 's-Hertogenbosch Jeroen J Kolkman, Medisch Spectrum Twente, Enschede Maarten J van der Laan, University Medical Center Groningen, Groningen Kaatje Lenaerts, Maastricht University Medical Center, Maastricht Adriaan Moelker, Erasmus MC University Medical Center, Rotterdam Desirée van Noord, Franciscus Gasthuis & Vlietland, Rotterdam Maikel P Peppelenbosch, Erasmus MC University Medical Center, Rotterdam André S van Petersen, Bernhoven Hospital, Uden Pepijn Rijnja, Medisch Spectrum Twente, Enschede Peter J van der Schaar, St Antonius Hospital, Nieuwegein Luke G Terlouw, Erasmus MC University Medical Center, Rotterdam Hence JM Verhagen, Erasmus MC University Medical Center, Rotterdam Jean Paul PM de Vries, University Medical Center Groningen, Groningen Dammis Vroegindeweij, Maasstad Hospital, Rotterdam review provides an overview on the clinical management of chronic mesenteric ischemia (CMI). CMI is defined as insufficient blood supply to the gastrointestinal tract, most often caused by atherosclerotic stenosis of one or more mesenteric arteries. Patients classically present with postprandial abdominal pain and weight loss. Read More

Chem Biol Interact 2019 Aug 5;308:20-44. Epub 2019 May 5.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada; Department of Pharmacology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada. Electronic address:

Ischemic heart disease (IHD) is a major cause of cardiovascular morbidity and mortality worldwide, which is characterized by an imbalance between cardiac oxygen supply and demand predominantly due to obstruction of coronary arteries. Activation of the innate immune system and the consequent inflammatory response plays a role in the pathogenesis of IHD. Where an excessive inflammatory response may contribute to adverse cardiac remodeling and fibrosis, making inflammation an important therapeutic target for improving outcomes of IHD. Read More

Expert Opin Drug Saf 2019 06 7;18(6):485-496. Epub 2019 May 7.

a Section of Medical Oncology, Department of Surgical, Oncological and Stomatological Sciences , University of Palermo , Palermo , Italy.

Introduction: The angiogenesis mechanism is considered a crucial point in neoplastic development. A growing number of multi-targeted tyrosine kinase inhibitors (TKI) has been developed and approved for cancer treatment during the last few years. Cardiac side effects still remain an issue to manage nowadays. Read More

Am J Blood Res 2019 15;9(1):1-14. Epub 2019 Feb 15.

Physiology Section, Department of Cell Biology, Physiology and Immunology, Universitat de Barcelona Barcelona, Spain.

The human body is a highly aerobic organism, in which it is necessary to match oxygen supply at tissue levels to the metabolic demands. Along metazoan evolution, an exquisite control developed because although oxygen is required as the final acceptor of electron respiratory chain, an excessive level could be potentially harmful. Understanding the role of the main factors affecting oxygen availability, such as the gradient of pressure of oxygen during normal conditions, and during hypoxia is an important point. Read More

J Plast Reconstr Aesthet Surg 2019 Apr 15;72(4):609-615. Epub 2019 Jan 15.

Department of Plastic Surgery, West Wing, John Radcliffe Hospital, Oxford University Hospitals, Oxford, OX3 9DU, United Kingdom.

Background: A comprehensive understanding of the anatomy of the vascular supply of the coracoid is needed to ensure that the coracoid remains vascularised in order to optimize bone union during any coracoid transfer procedures. It is the purpose of this study to present an anatomical overview of the blood supply of the coracoid process, describing a previously unidentified vessel that arises directly from the axillary artery and nourishes the coracoid process, permitting the coracoid to be used as a free bone flap.

Methods: An anatomical study examining the blood supply to the coracoid process of the scapula was performed in 14 shoulders from 7 fresh frozen (unembalmed) adult cadavers. Read More

J Vis Exp 2019 01 7(143). Epub 2019 Jan 7.

Department of Urology, Ghent University Hospital.

Urethroplasty is considered to be the standard treatment for urethral strictures since it provides excellent long-term success rates. For isolated short bulbar or posterior urethral strictures, urethroplasty by excision and primary anastomosis (EPA) is recommended. As EPA only requires the excision of the narrowed segment and the surrounding spongiofibrosis, a full-thickness transection of the corpus spongiosum, as performed in the traditional transecting EPA (tEPA), is usually unnecessary. Read More

Dermatology 2019 16;235(2):156-163. Epub 2019 Jan 16.

Área de Anatomía y Embriología Humana, Departamento de Ciencias Básicas de la Salud, Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Madrid, Spain.

Objective: Dermal fillers are an important tool in the field of aesthetic dermatology. Fillers are relatively noninvasive and easy to use but are not free of secondary complications. The main complications are vascular and are due to either the compression of an artery or the direct introduction of the product into the arterial lumen. Read More

Int J Mol Sci 2018 Dec 5;19(12). Epub 2018 Dec 5.

Department of Infectious Diseases, Hepatology and Acquired Immunodeficiencies, University of Medical Sciences, Poznań 61-285, Poland.

The liver is perfused by both arterial and venous blood, with a resulting abnormal microenvironment selecting for more-aggressive malignancies. Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer, the sixth most common cancer globally, and the third leading cause of cancer-related mortality worldwide. HCC is characterized by its hypervascularization. Read More

Clin Anat 2019 May 21;32(4):471-475. Epub 2018 Dec 21.

Department of Plastic and Reconstructive Surgery, Bundang CHA Medical Center, School of Medicine, CHA University, Seongnam, South Korea.

There are various modifications of the transverse rectus abdominis musculocutaneous flap and deep inferior epigastric perforator flap to reduce the morbidity of the donor site or to augment the vascularity of the flap. For microanastomosis of multiple pedicles, multiple recipient vessels or an intervening vein graft should be provided. In addition, alternative perforator-based flaps used in breast reconstruction have small caliber pedicles. Read More

Ann Anat 2019 Jan 6;221:115-124. Epub 2018 Oct 6.

Department of Anatomy, Jagiellonian University Medical College, Kraków, Poland. Electronic address:

Objectives: The aim of this study was to provide a comprehensive overview of the clinically relevant anatomical and histological aspects of the development of the human pancreas, with emphasis on the vascularization of the gland.

Methods: A comprehensive search on the relevant aspects of pancreatic biology was performed through the main electronic databases up to August 2017. Data from all relevant articles was gathered, analyzed and included in this narrative review. Read More

Ugeskr Laeger 2018 Aug;180(33)

Prostate artery embolisation (PAE) is a new minimally in-vasive treatment for prostate disease. Recent studies have shown, that PAE may be an alternative to transurethral resection of the prostate (TURP), and it reduces the prostate volume by 40%. The reduction in symptom score is com-parable to that of TURP, and only few major complications have been reported. Read More

Surg Radiol Anat 2018 Oct 1;40(10):1173-1175. Epub 2018 Aug 1.

Faculty of Medicine, University of Montenegro, Ljubljanska 1, 20000, Podgorica, Montenegro.

The middle cerebral artery, a terminal branch of the internal carotid artery, participates greatly in the blood supply of the cerebral cortex and basal nuclei. The aim of this paper is to present a case of middle cerebral artery duplication in a 3-day-old neonate. A brief literature overview in this paper serves to summarize the research on the middle cerebral artery duplication. Read More

Radiol Clin North Am 2018 Jul;56(4):521-534

Department of Radiology and Radiological Science, Division of Cardiovascular Imaging, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA. Electronic address:

Dual energy computed tomography is becoming increasingly widespread in clinical practice. It can expand on the traditional density-based data achievable with single energy computed tomography by adding novel applications to help reach a more accurate diagnosis. The implementation of this technology in cardiothoracic vascular imaging allows for improved image contrast, metal artifact reduction, generation of virtual unenhanced images, virtual calcium subtraction techniques, cardiac and pulmonary perfusion evaluation, and plaque characterization. Read More

World J Gastroenterol 2018 Jun;24(22):2348-2362

Department of Radiology, Sichuan University West China Hospital, Chengdu 610041, Sichuan Province, China.

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a major public health problem worldwide. Hepatocarcinogenesis is a complex multistep process at molecular, cellular, and histologic levels with key alterations that can be revealed by noninvasive imaging modalities. Therefore, imaging techniques play pivotal roles in the detection, characterization, staging, surveillance, and prognosis evaluation of HCC. Read More

Semin Cell Dev Biol 2019 07 6;91:132-146. Epub 2018 Jun 6.

Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, United States. Electronic address:

The kidney vasculature has a unique and complex architecture that is central for the kidney to exert its multiple and essential physiological functions with the ultimate goal of maintaining homeostasis. An appropriate development and coordinated assembly of the different vascular cell types and their association with the corresponding nephrons is crucial for the generation of a functioning kidney. In this review we provide an overview of the renal vascular anatomy, histology, and current knowledge of the embryological origin and molecular pathways involved in its development. Read More

Contrast Media Mol Imaging 2018 8;2018:5360375. Epub 2018 May 8.

Department of Brain Repair & Rehabilitation, UCL Institute of Neurology, London, UK.

Arterial spin labelling (ASL) allows absolute quantification of CBF via a diffusible intrinsic tracer (magnetically labelled blood water) that disperses from the vascular system into neighbouring tissue. Thus, it can provide absolute CBF quantification, which eliminates the need for the contrast agent, and can be performed repeatedly. This review will focus on the common ASL acquisition techniques (continuous, pulsed, and pseudocontinuous ASL) and how ASL image quality might be affected by intrinsic factors that may bias the CBF measurements. Read More

Vestn Otorinolaringol 2018;83(2):67-72

Orenburg State Medical University, Ministry of Health of the Russian Federation, Orenburg, Russia, 460000.

The objective of the present work was to overview the currently available literature data on microtopographic anatomy of the anterior portion of the middle ear and the external auditory passage. Manipulations on these structures during miringoplasty surgery appear to be the most difficult and laborious operations because this space is anatomically very narrow and curved; moreover, it contains the important intimate structures of the middle ear and is located very close to the temporomandibular joint. The knowledge of microsurgical anatomy of the anterior part of the middle ear and the external auditory passage is paramount in the context of the improvement of the professional skills of the surgeons. Read More

Compr Physiol 2018 03 25;8(2):773-799. Epub 2018 Mar 25.

Charlie Norwood VA Medical Center, Augusta, Georgia, USA.

Metabolic diseases including obesity, insulin resistance, and diabetes have profound effects on cerebral circulation. These diseases not only affect the architecture of cerebral blood arteries causing adverse remodeling, pathological neovascularization, and vasoregression but also alter the physiology of blood vessels resulting in compromised myogenic reactivity, neurovascular uncoupling, and endothelial dysfunction. Coupled with the disruption of blood brain barrier (BBB) integrity, changes in blood flow and microbleeds into the brain rapidly occur. Read More

Curr Opin Pharmacol 2018 04 18;39:105-112. Epub 2018 Apr 18.

1st Department of Cardiology, 'Hippokration' Hospital, University of Athens, Medical School, Athens, Greece. Electronic address:

Peripheral artery disease (PAD) is a vascular problem of diffuse atherosclerosis and is a major cause of cardiovascular morbidity and mortality. Many studies have tried to gain insight into the molecular mechanisms involved in PAD. Lately, highly stable circulating small noncoding RNAs, microRNAs (miRNAs), seem to have disease-specific expression. Read More

Nat Rev Cardiol 2018 06;15(6):332-350

Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, USA.

Peripheral artery disease (PAD) of the lower extremities is a common manifestation of atherosclerosis that is increasing in global prevalence and in the associated public health costs. Ageing of the general population, combined with the pandemics of diabetes mellitus, metabolic syndrome, and tobacco use, is a major underlying factor. A broad range of care providers are involved in the management of patients with PAD, and all health-care professionals require familiarity with the risk factors, diagnosis, and treatment options for this common disease. Read More

Neuroimage 2019 02 29;187:145-153. Epub 2018 Mar 29.

Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Maindy Road, CF24 4HQ, Cardiff, UK. Electronic address:

Functional magnetic resonance imaging (fMRI) is an essential workhorse of modern neuroscience, providing valuable insight into the functional organisation of the brain. The physiological mechanisms underlying the blood oxygenation level dependent (BOLD) effect are complex and preclude a straightforward interpretation of the signal. However, by employing appropriate calibration of the BOLD signal, quantitative measurements can be made of important physiological parameters including the absolute rate of cerebral metabolic oxygen consumption or oxygen metabolism (CMRO) and oxygen extraction (OEF). Read More

Clin Radiol 2019 01 2;74(1):13-28. Epub 2018 Mar 2.

Radiology, New York-Presbyterian Hospital, Columbia University, NY, USA; Radiology, Weill Cornell Medical Center, NY, USA.

Autologous breast reconstruction using muscle-sparing free flaps are becoming increasingly popular, although microvascular free flap reconstruction has been utilised for autologous breast reconstructions for >20 years. This innovative microsurgical technique involves meticulous dissection of artery-vein bundle (perforators) responsible for perfusion of the subcutaneous fat and skin of the flap; however, due to unpredictable anatomical variations, preoperative imaging of the donor site to select appropriate perforators has become routine. Preoperative imaging also reduces operating time and enhances the surgeon's confidence in choosing the appropriate donor site for harvesting flaps. Read More

Vasc Med 2018 04 19;23(2):163-171. Epub 2018 Feb 19.

1 School of Nursing, University of Minnesota, Minneapolis, MN, USA.

Peripheral artery disease (PAD) is a manifestation of generalized atherosclerosis which results in hemodynamic compromise of oxygen and substrate delivery to the lower extremity skeletal muscles. Hemodynamic assessments are vital in PAD diagnosis and in the evaluation of strategies aimed at treating claudication (i.e. Read More

Diagn Interv Imaging 2018 Mar 9;99(3):123-134. Epub 2018 Feb 9.

Department of Radiology, University Hospitals Paris Nord Val-de-Seine, Beaujon, 92110 Clichy, Hauts-de-Seine, France; University Paris Diderot, Sorbonne Paris Cité, 75018 Paris, France; Inserm U1149, centre de recherche biomédicale Bichat-Beaujon, CRB3, 92110 Paris, France. Electronic address:

Acute mesenteric ischemia is defined as an inadequate blood supply to the gastrointestinal tract resulting in ischemic and inflammatory injury that may progress to necrosis of the bowel wall. Prognosis is poor with a mortality rate greater than 95% without treatment, dropping to around 70% when surgical treatment is performed. Contrast-enhanced computed tomography (CT) has become the cornerstone of the diagnosis by showing features of vascular disorders (occlusion and/or insufficient blood supply) and features of intestinal ischemic injury. Read More

Obes Surg 2018 07;28(7):1822-1830

Department of Bariatric Surgery, Rijnstate Hospital and Vitalys Clinic, Wagnerlaan 55, 6815 AD, Arnhem, The Netherlands.

Purpose: The purposes of the study are to outline the complexity of diagnosing internal herniation after Roux-en-Y gastric bypass (RYGB) surgery and to investigate the added value of computed tomography angiography (CTA) for diagnosing internal herniation.

Materials And Methods: A cadaver study was performed to investigate the manifestations of internal hernias and mesenteric vascularization. Furthermore, a prospective, ethics approved study with retrospective interpretation was conducted. Read More

Int Angiol 2018 Apr 31;37(2):100-111. Epub 2018 Jan 31.

Clinic of Vascular and Internal Diseases, Jan Biziel University Hospital No. 2, Bydgoszcz, Poland.

Introduction: The association of lower limb ischemia (LLI) with disturbances in nutritional status, in respect to over- or undernutrition, is still uncertain. The aim of this study was to present the current state of knowledge on this issue.

Evidence Acquisition: Systematic review of papers published between 2006 and 2018. Read More

Anesth Analg 2019 02;128(2):265-277

Department of Anesthesiology and Intensive Care Medicine, University of Lübeck, Lübeck, Germany.

Maintaining brain function and integrity is a pivotal part of anesthesiological practice. The present overview aims to describe the current role of the 2 most frequently used monitoring methods for evaluation brain function in the perioperative period, ie, electroencephalography (EEG) and brain oxygenation monitoring. Available evidence suggests that EEG-derived parameters give additional information about depth of anesthesia for optimizing anesthetic titration. Read More

Eur Respir Rev 2018 Mar 24;27(147). Epub 2018 Jan 24.

Dept of Pediatric Surgery, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands

Congenital diaphragmatic hernia (CDH) is a rare congenital anomaly characterised by a diaphragmatic defect, persistent pulmonary hypertension (PH) and lung hypoplasia. The relative contribution of these three elements can vary considerably in individual patients. Most affected children suffer primarily from the associated PH, for which the therapeutic modalities are limited and frequently not evidence based. Read More

Neuroimage 2019 02 3;187:3-16. Epub 2018 Jan 3.

FMRI Laboratory, University of Michigan, United States.

This article aims to provide the reader with an overview of recent developments in Arterial Spin Labeling (ASL) MRI techniques. A great deal of progress has been made in recent years in terms of the SNR and acquisition speed. New strategies have been introduced to improve labeling efficiency, reduce artefacts, and estimate other relevant physiological parameters besides perfusion. Read More

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2018 Feb;61(2):218-223

Universitäres Herzzentrum Hamburg, Klinik und Poliklinik für Gefäßmedizin, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Deutschland.

Due to the paucity of independent trials, practical guidelines for the diagnosis and treatment of peripheral arterial disease (PAD) contain several recommendations developed by expert consensus. Furthermore, there is a lack of commonly defined quality indicators and valid data on real world treatment. Therefore, it remains challenging to scrutinize if treatment reality is conforming to guideline recommendations. Read More

World Neurosurg 2018 Mar 9;111:36-40. Epub 2017 Dec 9.

Department of Neurological Surgery, University of Louisville SOM, Louisville, Kentucky, USA.

Background: Spinal subarachnoid hemorrhage due to rupture of an isolated spinal aneurysm is extremely rare. Patients usually present with symptoms and signs resulting from spinal cord compression. No standard guidelines are available for the treatment of this condition. Read More