346 results match your criteria Arterial Supply Overview

Ocular Ischemic Syndrome and Its Related Experimental Models.

Int J Mol Sci 2022 May 8;23(9). Epub 2022 May 8.

Laboratory of Photobiology, Keio University School of Medicine, Tokyo 160-8582, Japan.

Ocular ischemic syndrome (OIS) is one of the severe ocular disorders occurring from stenosis or occlusion of the carotid arteries. As the ophthalmic artery is derived from the branch of the carotid artery, stenosis or occlusion of the carotid arteries could induce chronic ocular hypoperfusion, finally leading to the development of OIS. To date, the pathophysiology of OIS is still not clearly unraveled. Read More

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Perfusion imaging techniques in lower extremity peripheral arterial disease.

Br J Radiol 2022 Jul 12;95(1135):20211203. Epub 2022 May 12.

Department of Medical Imaging, University Hospital Heraklion, University of Crete Medical School, Heraklion, Greece.

Lower limb peripheral arterial disease (PAD) characterizes the impairment of blood flow to extremities caused by arterial stenoses or occlusions. Evaluation of PAD is based on clinical examination, calculation of ankle-brachial index and imaging studies such as ultrasound, CT, MRI and digital subtraction angiography. These modalities provide significant information about location, extension and severity of macrovasular lesions in lower extremity arterial system. Read More

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Myocardial Infarction With Non-obstructive Coronary Arteries: An Updated Overview of Pathophysiology, Diagnosis, and Management.

Cureus 2022 Mar 29;14(3):e23602. Epub 2022 Mar 29.

Internal Medicine, University of Pittsburgh Medical Center (UPMC) McKeesport Hospital, Pittsburgh, USA.

Myocardial infarction with non-obstructive coronary arteries (MINOCA) refers to acute myocardial infarction with normal or near-normal coronary arteries. The MINOCA is a heterogeneous group of conditions, and possible etiologies are coronary artery spasm, spontaneous coronary artery dissection, coronary thromboembolism, coronary plaque disruption, coronary microvascular dysfunction, supply and demand mismatch. It is more common in young adults, with women having a higher chance of getting MINOCA than men. Read More

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Transarterial Embolization of Ethmoidal Dural Arteriovenous Fistula: 2-Dimensional Video.

Oper Neurosurg (Hagerstown) 2022 Apr 5. Epub 2022 Apr 5.

Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Cranial dural arteriovenous fistulae (dAVF) are rare cerebrovascular lesions characterized by direct arteriovenous shunting within the dural leaflets, with stark heterogeneity in angioarchitecture among different patients.1,2 It is, therefore, crucial to personalize treatment strategies to unique patients and their specific lesion. The authors describe an ethmoidal dAVF in an elderly female patient with arterial supply from the ophthalmic arteries and the contralateral middle meningeal artery. Read More

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Surgical anatomy of hepatic arteries from its origin to segmental branching: A 500 cases CT study.

Am J Surg 2022 Jul 9;224(1 Pt B):506-513. Epub 2022 Mar 9.

Department of Radiology, CHRU Nancy, 54 511 Vandœuvre-lès-Nancy, France; IADI, U1254, INSERM and Université de Lorraine, 54 511 Vandœuvre-lès-Nancy, France; Université de Lorraine, 54 511 Vandœuvre-lès-Nancy, France.

Background: The aim of this study was to present an overview of variations of the hepatic artery from the origin to the segmental branching.

Methods: Abdominal Computed Tomography performed on consecutive patients in our tertiary center between 2019 and 2020 were analyzed. Hepatic arterial branching and its relationship to the portal veins were reported. Read More

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Contribution of vascular smooth muscle cell apoptosis to spiral artery remodeling in early human pregnancy.

Placenta 2022 03 9;120:10-17. Epub 2022 Feb 9.

Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. Electronic address:

Uterine spiral artery remodeling is one of the key maternal adaptations of pregnancy, allowing delivery of the large volumes of maternal blood required for both placental and fetal growth. Failure of this process is associated with obstetric complications including preeclampsia, fetal growth restriction and miscarriage. Spiral artery remodeling is characterized by loss of the musculoelastic wall which is replaced by fibrinoid and intramural extravillous trophoblast cells (EVT). Read More

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Rethinking the necessity of low glucose intervention for cerebral ischemia/reperfusion injury.

Neural Regen Res 2022 Jul;17(7):1397-1403

Department of Pharmaceutical Sciences, Biomanufacturing Research Institute & Technology Enterprise, North Carolina Central University, Durham, NC, USA.

Glucose is the essential and almost exclusive metabolic fuel for the brain. Ischemic stroke caused by a blockage in one or more cerebral arteries quickly leads to a lack of regional cerebral blood supply resulting in severe glucose deprivation with subsequent induction of cellular homeostasis disturbance and eventual neuronal death. To make up ischemia-mediated adenosine 5'-triphosphate depletion, glucose in the ischemic penumbra area rapidly enters anaerobic metabolism to produce glycolytic adenosine 5'-triphosphate for cell survival. Read More

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Overview of commercial treatment planning systems for targeted radionuclide therapy.

Phys Med 2021 Dec 2;92:52-61. Epub 2021 Dec 2.

Department of Medical Physics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. Electronic address:

Introduction: Targeted Radionuclide Therapy (TRT) is a branch of cancer medicine dealing with the therapeutic use of radioisotopes associated with biological vectors accumulating in the tumors/targets, indicated as Molecular Radiotherapy (MRT), or directly injected into the arteries that supply blood to liver tumour vasculature, indicated as Selective RT (SRT). The aim of this work is to offer a panoramic view on the increasing number of commercially-available TRT treatment planning systems (TPSs).

Materials And Methods: A questionnaire was sent to manufacturers' representatives. Read More

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December 2021

Avoiding Misdiagnosis of Abdominal Vascular Catastrophes.

Emerg Med Clin North Am 2021 Nov 6;39(4):769-780. Epub 2021 Sep 6.

Mayo Clinic, 2204 Baihly Vista Ln SW, Rochester, MN 55902, USA.

Abdominal vascular emergencies are an uncommon entity in emergency medicine, but when they present, they are often catastrophic. These time-sensitive and life-threatening diagnoses are often hidden in nonspecific complaints such as nausea, vomiting, or flank pain, so the emergency physician must remain diligent and consider these in the differential diagnoses. The following is an overview of the more common of these abdominal vascular emergencies, in the hope that they help the Emergency Physician avoid the misdiagnosis and subsequent vascular catastrophe that would follow. Read More

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November 2021

Microsurgical Neurovascular Anatomy of the Brain: The Anterior Circulation (Part I).

Acta Biomed 2021 08 26;92(S4):e2021412. Epub 2021 Aug 26.

Neurosurgery Unit, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy; Neurosurgery Unit, Department of Surgical Sciences, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy..

Introduction Treatment of cranial neurovascular pathology requires a detailed understanding of the brain, head, and neck vasculature. This study aims at a comprehensive overview of the microsurgical anatomy of the anterior cerebral circulation. Methods Five formalin-fixed adult cadaveric heads were used. Read More

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Microsurgical Neurovascular Anatomy of the Brain: The Posterior Circulation (Part II).

Acta Biomed 2021 08 26;92(S4):e2021413. Epub 2021 Aug 26.

Neurosurgery Unit, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy; Neurosurgery Unit, Department of Surgical Sciences, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy..

Introduction Vascular complications of posterior fossa surgery are often deadly although widely preventable through in-depth knowledge of the microsurgical neurovascular anatomy of the infratentorial region and careful surgical planning.   The target of this study is to provide a synoptic overview of the normal anatomy and anatomic variants of the infratentorial neurovascular system, critical to safely operate tumors and neurovascular pathologies of the posterior fossa. Methods Two fresh-frozen and five formalin-fixed cadaveric heads were used. Read More

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Genetic Determinants of Peripheral Artery Disease.

Circ Res 2021 06 10;128(12):1805-1817. Epub 2021 Jun 10.

Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA (S.M.D.).

Peripheral artery disease-atherosclerosis of the abdominal aorta and lower extremity vascular bed-is a complex disease with both environmental and genetic determinants. Unmitigated disease is associated with major functional decline and can lead to chronic limb-threatening ischemia, amputation, and increased mortality. Over the last 10 years, major advances have been made in identifying the genetic basis of this common, complex disease. Read More

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Therapeutic Biomaterial Approaches to Alleviate Chronic Limb Threatening Ischemia.

Adv Sci (Weinh) 2021 04 8;8(7):2003119. Epub 2021 Feb 8.

CÚRAM SFI Research Centre for Medical Devices National University of Ireland Galway Ireland.

Chronic limb threatening ischemia (CLTI) is a severe condition defined by the blockage of arteries in the lower extremities that leads to the degeneration of blood vessels and is characterized by the formation of non-healing ulcers and necrosis. The gold standard therapies such as bypass and endovascular surgery aim at the removal of the blockage. These therapies are not suitable for the so-called "no option patients" which present multiple artery occlusions with a likelihood of significant limb amputation. Read More

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Vascular endothelial cell specification in health and disease.

Angiogenesis 2021 05 12;24(2):213-236. Epub 2021 Apr 12.

Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.

There are two vascular networks in mammals that coordinately function as the main supply and drainage systems of the body. The blood vasculature carries oxygen, nutrients, circulating cells, and soluble factors to and from every tissue. The lymphatic vasculature maintains interstitial fluid homeostasis, transports hematopoietic cells for immune surveillance, and absorbs fat from the gastrointestinal tract. Read More

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The Use of Near Infrared Spectroscopy to Evaluate the Effect of Exercise on Peripheral Muscle Oxygenation in Patients with Lower Extremity Artery Disease: A Systematic Review.

Eur J Vasc Endovasc Surg 2021 05 30;61(5):837-847. Epub 2021 Mar 30.

Department of Rehabilitation sciences, KU Leuven, Leuven, Belgium.

Objective: Near infrared spectroscopy (NIRS) has been suggested as a new diagnostic tool in patients with lower extremity artery disease (LEAD). The aim of this systematic review was to summarise the impact of exercise therapy on lower limb muscle oxygenation, evaluated by NIRS, in patients with LEAD, and to give an overview on NIRS instruments and methodology.

Data Sources: MEDLINE and Embase. Read More

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Current Status of Angiogenic Cell Therapy and Related Strategies Applied in Critical Limb Ischemia.

Int J Mol Sci 2021 Feb 26;22(5). Epub 2021 Feb 26.

Biomedicine, Biotechnology and Public Health Department, Cádiz University, 11519 Cadiz, Spain.

Critical limb ischemia (CLI) constitutes the most severe form of peripheral arterial disease (PAD), it is characterized by progressive blockade of arterial vessels, commonly correlated to atherosclerosis. Currently, revascularization strategies (bypass grafting, angioplasty) remain the first option for CLI patients, although less than 45% of them are eligible for surgical intervention mainly due to associated comorbidities. Moreover, patients usually require amputation in the short-term. Read More

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February 2021

Neurologic complications of diseases of the aorta.

Handb Clin Neurol 2021 ;177:221-239

Department of Neurology, Mayo Clinic, Rochester, MN, United States.

Neurologic complications of diseases of the aorta are common, as the brain and spinal cord function is highly dependent on the aorta and its branches for blood supply. Any disease impacting the aorta may have significant impact on the ability to deliver oxygenated blood to the central nervous system, resulting in ischemia-and if prolonged-cerebral and spinal infarct. The breadth of pathology affecting the aorta is diverse and neurologic complications can vary dramatically based on the location, severity, and underlying etiology. Read More

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Hepatic Arterial Variations and Its Implication During Pancreatic Cancer Surgeries.

J Gastrointest Cancer 2021 Jun 22;52(2):462-470. Epub 2021 Feb 22.

Department of Anatomy, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Purpose: Aberrant hepatic artery anatomy is a considerable challenge during pancreatic surgery as it warrants extreme caution for the preservation of vascular supply as well as achievement of R0 resection margin.

Method: We reviewed the literature about the aberrant anatomical variations of the hepatic artery and its relevance during pancreatoduodenectomy and distal pancreatectomy.

Result: Preoperative deliberation of peri-pancreatic vascular anatomy using advanced imaging methods is crucial for surgeons. Read More

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An overview of hepatocellular carcinoma with atypical enhancement pattern: spectrum of magnetic resonance imaging findings with pathologic correlation.

Radiol Oncol 2021 01 29;55(2):130-143. Epub 2021 Jan 29.

Department of Gastrointestinal Radiology, NorthShore University, Evanston, Pritzker School of Medicine at the University of Chicago, ChicagoUSA.

Background: In the setting of cirrhotic liver, the diagnosis of hepatocellular carcinoma (HCC) is straightforward when typical imaging findings consisting of arterial hypervascularity followed by portal-venous washout are present in nodules larger than 1 cm. However, due to the complexity of hepatocarcinogenesis, not all HCCs present with typical vascular behaviour. Atypical forms such as hypervascular HCC without washout, isovascular or even hypovascular HCC can pose diagnostic dilemmas. Read More

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January 2021

Modern multidisciplinary team approach is crucial in treatment for critical limb threatening ischemia.

J Cardiovasc Surg (Torino) 2021 Apr 26;62(2):124-129. Epub 2021 Jan 26.

Division of Interventional Radiology, Miami Cardiac and Vascular Institute, FIU Herbert Wertheim College of Medicine, Miami, FL, USA.

The aim of this study was to provide a brief overview of the history the multidisciplinary team approach, highlighting the benefit to the patient with critical limb threatening ischemia in relation to health care economics. Furthermore, we provided a description of the requisites and key components, showing how to build a multidisciplinary team. Read More

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Drug-eluting embolic microspheres: State-of-the-art and emerging clinical applications.

Expert Opin Drug Deliv 2021 03 22;18(3):383-398. Epub 2021 Jan 22.

Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, USA.

Introduction: Drug-eluting embolic (DEE) microspheres, or drug-eluting beads (DEB), delivered by transarterial chemoembolization (TACE) serve as a therapeutic embolic to stop blood flow to tumors and a drug delivery vehicle. New combinations of drugs and DEE microspheres may exploit the potential synergy between mechanisms of drug activity and local tissue responses generated by TACE to enhance the efficacy of this mainstay therapy.

Areas Covered: This review provides an overview of key drug delivery concepts related to DEE microspheres with a focus on recent technological developments and promising emerging clinical applications as well as speculation into the future. Read More

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Hypertrophic anterior choroidal artery: images and brief embryological overview.

BMJ Case Rep 2021 Jan 8;14(1). Epub 2021 Jan 8.

Neurology, Institute of Postgraduate Medical Education and Research Bangur Institute of Neurology, Kolkata, West Bengal, India.

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January 2021

Pulmonary sequestration: What the radiologist should know.

Clin Imaging 2021 May 3;73:61-72. Epub 2020 Dec 3.

Diagnostic and Interventional Radiology, Department of Translational Research, University of Pisa, Via Roma, 67, 56126 Pisa, Italy.

Pulmonary sequestration consists of a nonfunctioning mass of lung tissue, either sharing the pleural envelope of the normal lung (intralobar) or with its own pleura (extralobar), lacking normal communication with the tracheobronchial tree and receiving its arterial supply by one or more systemic vessels. It is the second most common congenital lung anomaly according to pediatric case series, but its real prevalence is likely to be underestimated, and imaging plays a key role in the diagnosis and treatment management of the condition and its potential complications. We will give a brief overview of the pathophysiology, clinical presentation and imaging findings of intra- and extralobar pulmonary sequestration, with particular reference to multidetector computed tomography as part of a powerful and streamlined diagnostic approach. Read More

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Current Status of Cell-Based Therapy in Patients with Critical Limb Ischemia.

Int J Mol Sci 2020 Nov 26;21(23). Epub 2020 Nov 26.

Radiodiagnostic Institute, University Hospital Ostrava, 708 52 Ostrava, Czech Republic.

(1) Background: The treatment of peripheral arterial disease (PAD) is focused on improving perfusion and oxygenation in the affected limb. Standard revascularization methods include bypass surgery, endovascular interventional procedures, or hybrid revascularization. Cell-based therapy can be an alternative strategy for patients with no-option critical limb ischemia who are not eligible for endovascular or surgical procedures. Read More

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November 2020

Antiplatelet and anticoagulation therapy after revascularization for lower extremity artery disease: a national survey and literature overview.

J Cardiovasc Surg (Torino) 2021 Feb 28;62(1):59-70. Epub 2020 Oct 28.

Department of Vascular Surgery, Northwest Clinics, Alkmaar, the Netherlands.

Background: Antiplatelet therapy (APT) after interventions for lower extremity artery disease (LEAD) is recommended. However, (inter)national guidelines vary on type and duration of APT. This report aimed to present the results of a survey on antithrombotic prescribing patterns after lower limb interventions in the Netherlands and an overview of the available literature on this topic. Read More

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February 2021

Osteocutaneous proximal fibular flap: an anatomical and computed tomographic angiographic study of skin and bone perforators.

Surg Radiol Anat 2021 Jul 12;43(7):1099-1106. Epub 2020 Oct 12.

Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.

Introduction: Vascularized proximal fibular epiphyseal transfer is a reconstruction method for joints and growing bones. The authors investigated the vascular supply of the proximal fibula, including skin perforators, for suitability in creating an osteocutaneous flap.

Methods: Twenty fresh cadaveric knees were studied using computed tomographic angiography combined with anatomical dissection. Read More

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Limits and pitfalls of indirect revascularization in moyamoya disease and syndrome.

Neurosurg Rev 2021 Aug 21;44(4):1877-1887. Epub 2020 Sep 21.

Department of Neurosurgery, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini, Genoa, Italy.

Moyamoya vasculopathy is a rare chronic cerebrovascular disorder characterized by the stenosis of the terminal branches of the internal carotid arteries and the proximal tracts of anterior and middle cerebral arteries. Although surgical revascularization does not significantly change the underlying pathogenic mechanisms, it plays a pivotal role in the management of affected individuals, allowing to decrease the risk of ischemic and hemorrhagic complications. Surgical approaches may be direct (extracranial-intracranial bypass), indirect, or a combination of the two. Read More

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Neopterin derivatives - a novel therapeutic target rather than biomarker for atherosclerosis and related diseases.

Takuya Watanabe

Vasa 2021 Apr 14;50(3):165-173. Epub 2020 Sep 14.

Department of Internal Medicine, Ushioda General Hospital/Clinic, Yokohama, Japan.

This review provides an updated overview of the emerging roles of neopterin derivatives in atherosclerosis. Neopterin, a metabolite of guanosine triphosphate, is produced by interferon-γ-activated macrophages and is expressed at high levels in atheromatous plaques within the human carotid and coronary arteries as well as in the aorta. Plasma concentrations of neopterin are higher in patients with carotid, cerebral, and coronary artery diseases as well as aortic aneurysm. Read More

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The relevance of the artery of Adamkiewicz for microsurgical resection of spinal tumors- short overview and case series: Technical note.

Neurochirurgie 2020 Nov 11;66(5):378-382. Epub 2020 Aug 11.

Service de neurochirurgie, CHU de Bicêtre, hôpitaux universitaires Paris-Sud, AP-HP, Paris, France.

Introduction: There is of major interest to know the exact anatomical location of artery of Adamkiewicz (AKA) for many spinal microsurgical procedures, so as to avoid postoperative ischemia of the spinal cord, with further devastating clinical impact.

Methods And Results: We detail the interest of preoperative angiography for medullary lesions in our experience. We further report two cases where the AKA was located at the same level and side with the treated lesion. Read More

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November 2020