236,396 results match your criteria Arrhythmia & electrophysiology review[Journal]


Radiotherapy Workflow and Dosimetric Analysis from a Phase I/II Trial of Noninvasive Cardiac Radioablation for Ventricular Tachycardia.

Int J Radiat Oncol Biol Phys 2019 Apr 16. Epub 2019 Apr 16.

Department of Radiation Oncology, Washington University School of Medicine, Saint Louis, MO.

Introduction: A prospective phase I/II trial for electrophysiologic-guided noninvasive cardiac radioablation treatment of ventricular tachycardia (VT) (XXXX) demonstrating efficacy for arrhythmia control has recently been reported. The treatment workflow, report dose-volume metrics, and overall process improvements are described here.

Methods: Patients receiving 25 Gy in a single fraction to the cardiac VT substrate (identified on pre-simulation multimodality imaging) on the phase I/II trial were included for analysis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2019.04.005DOI Listing

CARDIAC INVOLVEMENT IN Beta-THALASSAEMIA: Current treatment strategies.

Postgrad Med 2019 Apr 19. Epub 2019 Apr 19.

e Department of Medicine , Sultan Qaboos University Hospital , Muscat , Oman.

Despite the advances in the management of thalassaemia major, heart disease remains the leading cause of mortality in patients afflicted with this disorder. Cardiac involvement in thalassaemia encompasses a spectrum of disorders including myocardial dysfunction, arrhythmias, pulmonary hypertension and peripheral vascular disease. Although cardiac siderosis (accumulation of iron in cardiac myocytes) as a consequence of repeated blood transfusions is deemed to be the main aetiologic factor for myocardial dysfunction in transfusion dependent patients, the significance of other pathophysiologic mechanisms is being increasingly recognized especially in non-transfusion dependent patients. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/00325481.2019.1
Publisher Site
http://dx.doi.org/10.1080/00325481.2019.1608071DOI Listing
April 2019
1 Read

Therapeutic Challenges in Management of Severe Acidosis and Profound Hypokalemia in Pediatric Diabetic Ketoacidosis.

Glob Pediatr Health 2019 8;6:2333794X19840364. Epub 2019 Apr 8.

Beaumont Health System, Royal Oak, MI, USA.

Profound hypokalemia in the presence of diabetic ketoacidosis (DKA) is life-threatening condition predisposing patients to cardiac arrhythmias and potentially death. Rarely do patients present with profound hypokalemia (serum K level <2.5 mEq/L). Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/2333794X19840364
Publisher Site
http://dx.doi.org/10.1177/2333794X19840364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454640PMC
April 2019
1 Read

Extended Bidomain Modeling of Defibrillation: Quantifying Virtual Electrode Strengths in Fibrotic Myocardium.

Front Physiol 2019 3;10:337. Epub 2019 Apr 3.

Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT, United States.

Defibrillation is a well-established therapy for atrial and ventricular arrhythmia. Here, we shed light on defibrillation in the fibrotic heart. Using the extended bidomain model of electrical conduction in cardiac tissue, we assessed the influence of fibrosis on the strength of virtual electrodes caused by extracellular electrical current. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphys.2019.00337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456788PMC

Anomalous Coronary Artery Origin and Sudden Cardiac Death: Clinical and Pathological Insights From a National Pathology Registry.

JACC Clin Electrophysiol 2019 Apr 30;5(4):516-522. Epub 2019 Jan 30.

Cardiovascular Pathology Department, St. George's, University of London, London, United Kingdom. Electronic address:

Objectives: This study sought to describe the clinical and pathological features of anomalous origin of a coronary artery (AOCA) in sudden cardiac death (SCD) victims.

Background: AOCA from the inappropriate sinus of Valsalva or from the pulmonary artery is increasingly diagnosed with current imaging techniques. AOCA is a possible cause of SCD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacep.2018.11.015DOI Listing

Comparison of Ajmaline and Procainamide Provocation Tests in the Diagnosis of Brugada Syndrome.

JACC Clin Electrophysiol 2019 Apr 27;5(4):504-512. Epub 2019 Mar 27.

Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

Objectives: The authors studied the response rates and relative sensitivity of the most common agents used in the sodium-channel blocker (SCB) challenge.

Background: A type 1 Brugada electrocardiographic pattern precipitated by an SCB challenge confers a diagnosis of Brugada syndrome.

Methods: Patients undergoing an SCB challenge were prospectively enrolled across Canada and the United Kingdom. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacep.2019.01.026DOI Listing

Evidence for a Heritable Contribution to Atrial Fibrillation Associated With Fibrosis.

JACC Clin Electrophysiol 2019 Apr 27;5(4):493-500. Epub 2019 Feb 27.

Comprehensive Arrhythmia Research and Management Center, University of Utah Health, Salt Lake City, Utah; Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah; Huntsman Cancer Institute, Salt Lake City, Utah; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah. Electronic address:

Objectives: The aim of this study was to define the population-based familial clustering of atrial fibrillation (AF) that is associated with fibrosis and describe evidence for a heritable predisposition.

Background: Although a heritable contribution to AF is well-established and the association of fibrosis with AF is well-recognized, no studies have analyzed the genetic contribution to AF co-occurring with fibrosis.

Methods: AF patients with magnetic resonance imaging-confirmed fibrosis were identified in a population-based health sciences center database linked to a Utah genealogy. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S2405500X193001
Publisher Site
http://dx.doi.org/10.1016/j.jacep.2019.01.002DOI Listing
April 2019
1 Read

Ventricular Arrhythmias in Ischemic Cardiomyopathy: Is Imaging-Based Entropy a Biologically Relevant Risk Marker?

JACC Clin Electrophysiol 2019 Apr;5(4):490-492

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacep.2018.11.017DOI Listing

Entropy as a Novel Measure of Myocardial Tissue Heterogeneity for Prediction of Ventricular Arrhythmias and Mortality in Post-Infarct Patients.

JACC Clin Electrophysiol 2019 Apr 27;5(4):480-489. Epub 2019 Feb 27.

Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

Objectives: This study proposed entropy as a new late gadolinium enhanced cardiac magnetic resonance-derived parameter to evaluate tissue inhomogeneity, independent of signal intensity thresholds. This study hypothesized that entropy within the scar is associated with ventricular arrhythmias (VAs), whereas entropy of the entire left ventricular (LV) myocardium is associated with mortality.

Background: In patients after myocardial infarction, the heterogeneity of fibrosis determines the substrate for VA. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S2405500X183103
Publisher Site
http://dx.doi.org/10.1016/j.jacep.2018.12.005DOI Listing
April 2019
1 Read

Atrial Arrhythmias in Patients With Left Ventricular Assist Devices: To Treat or Not to Treat?

JACC Clin Electrophysiol 2019 Apr;5(4):467-469

Center for Arrhythmia Care, Pritzker School of Medicine, Department of Medicine, Section of Cardiology, The University of Chicago Medicine, Chicago, Illinois.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S2405500X193015
Publisher Site
http://dx.doi.org/10.1016/j.jacep.2019.02.007DOI Listing
April 2019
1 Read

Atrial Tachycardia Arising From the Crista Terminalis, Detailed Electrophysiological Features and Long-Term Ablation Outcomes.

JACC Clin Electrophysiol 2019 Apr 27;5(4):448-458. Epub 2019 Mar 27.

Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia; Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Parkville, Victoria, Australia. Electronic address:

Objectives: The goal of this study was to characterize, in detail, focal atrial tachycardia (AT) arising from the crista terminalis to investigate associations with other atrial arrhythmia and to define long-term ablation outcomes.

Background: The crista terminalis is known to be the most common site of origin for focal AT, but it is not well characterized.

Methods: This study retrospectively identified a total of 548 ablation procedures for AT performed at a single center over a 16-year period, of which 171 were arising from the crista terminalis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacep.2019.01.014DOI Listing

Catheter Ablation for Atrial Tachycardia in Adults With Congenital Heart Disease: Electrophysiological Predictors of Acute Procedural Success and Post-Procedure Atrial Tachycardia Recurrence.

JACC Clin Electrophysiol 2019 Apr 30;5(4):438-447. Epub 2019 Jan 30.

Cardiac Electrophysiology Unit, Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, New York. Electronic address:

Objectives: This study sought to determine the electrophysiological predictors of acute procedural success and of post-ablation recurrence of atrial tachyarrhythmias (ATs) in our adult congenital heart disease (ACHD) population undergoing catheter ablation for treatment of AT.

Background: Catheter ablation is frequently performed to treat persistent AT in ACHD. The predictors of post-ablation AT recurrence have not been well studied in the ACHD population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacep.2018.10.011DOI Listing

High-Density Mapping and Ablation of Primary Nonfocal Left Atrial Tachycardia: Characterizing a Distinct Arrhythmogenic Substrate.

JACC Clin Electrophysiol 2019 Apr 27;5(4):417-426. Epub 2019 Mar 27.

Department of Cardiology-Electrophysiology, University Hospital Hamburg, University Heart Center, and the DZHK Hamburg, Hamburg, Germany.

Objectives: This study sought to characterize primary left atrial tachycardia (LAT) mechanisms, electrical properties and substrate using high-density mapping.

Background: Nonfocal LAT can be found in patients without prior substrate modifying interventions.

Methods: Of 223 catheter ablation procedures for LAT 15 patients (60% male, age 74 ± 6 years) had nonfocal AT and no history of LA ablation or cardiac surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacep.2019.02.002DOI Listing

Associations of serum and dialysate electrolytes with QT interval and prolongation in incident hemodialysis: the Predictors of Arrhythmic and Cardiovascular Risk in End-Stage Renal Disease (PACE) study.

BMC Nephrol 2019 Apr 18;20(1):133. Epub 2019 Apr 18.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Background: Prolonged QT interval in hemodialysis patients may be associated with sudden cardiac death, however, few studies examined the longitudinal associations of modifiable factors such as serum and dialysate concentrations of calcium, potassium, and magnesium with corrected QT (QTc) prolongation in incident hemodialysis patients.

Methods: In 330 in-center hemodialysis participants from the PACE study who were followed up for one year, we examined the associations of predialysis serum electrolytes (total calcium [Ca], corrected Ca [cCa], ionized Ca [iCa], potassium [K], magnesium [Mg]), dialysate (dCa and dK), and serum-to-dialysate gradient measures with QTc interval and prolongation (≥460 ms in women and ≥ 450 ms in men).

Results: At the first study visit, 47% had QTc prolongation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12882-019-1282-5DOI Listing

Multicentre experience with the evolution rl mechanical sheath for lead extraction using a stepwise approach: safety, effectiveness and outcome.

Pacing Clin Electrophysiol 2019 Apr 17. Epub 2019 Apr 17.

Department of Cardiology and Cardiothoracic Surgery, Arrhythmia Unit and Electrophysiology Laboratories, Ospedale San Raffaele, Milan, Italy.

Background: In addition to the Evolution RL sheath, tools by Cook Medical, supporting lead extraction (LE), are available. Data on their use are not reported in detail in previous studies. Moreover, data regarding outcome are lacking. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/pace.13700
Publisher Site
http://dx.doi.org/10.1111/pace.13700DOI Listing
April 2019
1 Read

The Netherlands Arrhythmogenic Cardiomyopathy Registry: design and status update.

Neth Heart J 2019 Apr 17. Epub 2019 Apr 17.

Durrer Centre for Cardiovascular Research, Netherlands Heart Institute, Utrecht, The Netherlands.

Background: Clinical research on arrhythmogenic cardiomyopathy (ACM) is typically limited by small patient numbers, retrospective study designs, and inconsistent definitions.

Aim: To create a large national ACM patient cohort with a vast amount of uniformly collected high-quality data that is readily available for future research.

Methods: This is a multicentre, longitudinal, observational cohort study that includes (1) patients with a definite ACM diagnosis, (2) at-risk relatives of ACM patients, and (3) ACM-associated mutation carriers. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12471-019-1270-1
Publisher Site
http://dx.doi.org/10.1007/s12471-019-1270-1DOI Listing
April 2019
1 Read

A case of fatal acebutolol poisoning: an illustration of the potential of molecular networking.

Int J Legal Med 2019 Apr 17. Epub 2019 Apr 17.

INSERM, INRA, CHU Rennes, Institut NuMeCan (Nutrition, Metabolism and Cancer), University Rennes, 35000, Rennes, France.

Acebutolol is a β1-selective adrenergic receptor antagonist with moderate membrane-stabilizing activity and intrinsic sympathomimetic activity; accordingly, the drug is indicated in hypertension, angina pectoris, and arrhythmia. However, acebutolol's beta-blocking properties also extend the QRS and QTc intervals, and may predispose the patient to ventricular tachydysrhythmia. Here, we report autopsy and toxicological findings on a fatal case of acebutolol self-poisoning in a 70-year-old woman. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00414-019-02062-9
Publisher Site
http://dx.doi.org/10.1007/s00414-019-02062-9DOI Listing
April 2019
2 Reads

Recurrent idiopathic polymorphic ventricular tachycardia/ventricular fibrillation successfully treated by cardiac sympathetic denervation.

HeartRhythm Case Rep 2019 Apr 26;5(4):229-232. Epub 2019 Jan 26.

Division of Cardiovascular Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrcr.2019.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453564PMC

Standardising practice in cardiology: reducing clinical variation and cost at Ochsner Health System.

Open Heart 2019 22;6(1):e000994. Epub 2019 Mar 22.

QURE Healthcare, San Francisco, California, USA.

Objective: Low quality and unwarranted clinical variation harm patients and increase unnecessary costs. Effective approaches to improve clinical and economic value have been difficult. The Ochsner Health System looked to improve clinical care quality and reduce unnecessary costs in cardiology using active measurement and customised feedback. Read More

View Article

Download full-text PDF

Source
http://openheart.bmj.com/lookup/doi/10.1136/openhrt-2018-000
Publisher Site
http://dx.doi.org/10.1136/openhrt-2018-000994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443124PMC
March 2019
1 Read

A case of desmoplakin mutation and delayed arrhythmogenic right ventricular cardiomyopathy/dysplasia after atrial septal defect closure.

J Cardiol Cases 2019 Apr 6;19(4):111-114. Epub 2019 Feb 6.

Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.

Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a slow-developing cardiomyopathy characterized by ventricular arrhythmias and fibrofatty replacement of the right ventricular (RV) myocardium. Its clinical diagnosis is challenging because of its variable clinical presentation and low genetic penetrance. We describe the case of a 67-year-old man who was diagnosed as having ARVC/D with a desmoplakin mutation that appeared after occlusion of an atrial septal defect (ASD). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jccase.2018.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451054PMC

Diffuse Coronary Artery Fistula Leading to Syncope and Treated by Transcatheter Coil Occlusion and a Defibrillator: A Case Report.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: Coronary artery fistulas connecting coronary arteries to cardiac cavities are rare but clinically significant anomalies.

Clinical Presentation And Intervention: A 47-year-old male patient presented with syncope. Left ventricular dysfunction was detected on echocardiography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500309DOI Listing

Catheter Ablation of Ventricular Arrhythmias.

N Engl J Med 2019 04;380(16):1555-1564

From the University of California, Los Angeles (UCLA), Cardiac Arrhythmia Center and Electrophysiology Programs, David Geffen School of Medicine at UCLA, Los Angeles.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMra1615244DOI Listing

Cardiovascular Disease: Cardioverter-Defibrillators and Left Ventricular Assist Devices.

FP Essent 2019 Apr;479:30-34

Womack Army Medical Center Department of the Army, WAMC Stop A 2817 Reilly Rd, Ft Bragg, NC 28310-7301.

Sudden cardiac death (SCD) is an abrupt and unexpected death presumed to be due to cardiac causes. The primary etiologic mechanism is cardiac arrest due to an arrhythmia. Cardioverter-defibrillators detect abnormal arrhythmia and abort the rhythm with an electrical shock. Read More

View Article

Download full-text PDF

Source
April 2019
2 Reads

[Percutaneous left atrial appendage closure in a patient with atrial fibrillation and Rendu-Osler-Weber disease].

G Ital Cardiol (Rome) 2019 Apr;20(4):36-39

U.O. Cardiologia, Azienda Ospedaliera Universitaria di Parma.

Atrial fibrillation is the most common cardiac arrhythmia worldwide and represents a major risk factor for cerebral embolic stroke. The standard therapy in the prevention of stroke is oral anticoagulation therapy (OAT). However, a considerable number of patients are unable to tolerate chronic OAT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1714/3146.31277DOI Listing
April 2019
1 Read

Use of Cardiac Computed Tomography and Magnetic Resonance Imaging in Case Management of Atrial Fibrillation with Catheter Ablation.

Korean J Radiol 2019 May;20(5):695-708

Department of Radiology, Korea University Anam Hospital, Seoul, Korea.

Atrial fibrillation (AF) is the most common arrhythmia associated with the risk of morbidity and mortality in clinical patients. AF is considered as an arrhythmia type that develops and progresses through close connection with cardiac structural arrhythmogenic substrates. Since the introduction of catheter ablation-mediated electrical isolation of arrhythmogenic substrates, cardiac imaging indicates improved treatment outcome and prognosis with appropriate candidate selection, ablation catheter guidance, and post-ablation follow-up. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3348/kjr.2018.0774DOI Listing

When and how does a single ventricular premature beat initiate and terminate supraventricular tachycardia?

Ann Noninvasive Electrocardiol 2019 Apr 16:e12650. Epub 2019 Apr 16.

Faculdade Ciências Médicas, Ciências Médicas-MG, Belo Horizonte, Brazil.

Background: The differential diagnosis of a supraventricular tachycardia (SVT) is accomplished using a number of pacing maneuvers. The incidence and mechanism of a single ventricular premature beat (VPB) on initiation and termination of tachycardia were evaluated during programmed electrical stimulation (PES) of the heart in patients with the two most common regular SVTs: atrioventricular re-entrant tachycardia (AVNRT) and orthodromic atrioventricular tachycardia (AVRT).

Methods: Three hundred and thirty-seven consecutive patients aged above 18 years with an inducible sustained AVNRT or AVRT were prospectively enrolled. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/anec.12650DOI Listing

Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease.

Clin Endocrinol (Oxf) 2019 Apr 16. Epub 2019 Apr 16.

Institute of Applied Health Research, University of Birmingham, Birmingham, Edgbaston, United Kingdom, B15 2TT.

Context: The incidence of differentiated thyroid cancer (DTC) is increasing, yet the prognosis is favorable and long-term survival is expected. Exogenous TSH suppression has been used for many years to prevent DTC recurrence and may be associated with increased risks of circulatory diseases.

Design: Risks of circulatory disease in patients treated for DTC were compared to randomly matched patients without DTC (controls) up to a 1:5 ratio using age, sex, body mass index (BMI) and smoking as the matching parameters in a population-based, open cohort study using The Health Improvement Network. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cen.13990DOI Listing

Left atrial longitudinal strain by speckle tracking as independent predictor of recurrence after electrical cardioversion in persistent and long standing persistent non-valvular atrial fibrillation.

Int J Cardiovasc Imaging 2019 Apr 16. Epub 2019 Apr 16.

Division of Cardiology, UMAE Hospital de Cardiología, Centro Médico Nacional Siglo XXI, IMSS, 330 Cuauhtémoc Av, Doctores, Cuauhtémoc, 06720, Mexico City, Mexico.

Atrial fibrillation (AF) is the most common arrhythmia in humans. After successful cardioversion, there is a recurrence of 60% due to atrial remodeling, and it has been shown that the global peak atrial longitudinal strain (GPALS) is decreased in these subjects. The aim of this study was to evaluate the predictive value of GPALS for AF recurrence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10554-019-01597-7DOI Listing
April 2019
1 Read

Clinical safety and efficacy of tolvaptan for acute phase therapy in patients with low-flow and normal-flow severe aortic stenosis.

Heart Vessels 2019 Apr 16. Epub 2019 Apr 16.

Division of Cardiology, Department of Internal Medicine, Teikyo University, 2-11-1 Kaga, Tokyo, 173-8606, Japan.

Conventional diuretic therapy for low-flow (LF) severe aortic stenosis (SAS) often has an inadequate effect or causes hemodynamic instability. Tolvaptan is used for acute heart failure in addition to conventional diuretics, and it does not cause intravascular dehydration. This study aimed to retrospectively investigate the safety and efficacy of tolvaptan in the acute phase in 56 consecutive patients with SAS and compared LF-SAS with normal-flow (NF) SAS. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00380-019-01411-3
Publisher Site
http://dx.doi.org/10.1007/s00380-019-01411-3DOI Listing
April 2019
5 Reads

Focal scar and diffuse myocardial fibrosis are independent imaging markers in repaired tetralogy of Fallot.

Eur Heart J Cardiovasc Imaging 2019 Apr 16. Epub 2019 Apr 16.

Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Avenue de Magellan, 33604 Pessac, France.

Aims: To identify the correlates of focal scar and diffuse fibrosis in patients with history of tetralogy of Fallot (TOF) repair.

Methods And Results: Consecutive patients with prior TOF repair underwent electrocardiogram, 24-h Holter, transthoracic echocardiography, exercise testing, and cardiac magnetic resonance (CMR) including cine imaging to assess ventricular volumes and ejection fraction, T1 mapping to assess left ventricular (LV) and right ventricular (RV) diffuse fibrosis, and free-breathing late gadolinium-enhanced imaging to quantify scar area at high spatial resolution. Structural imaging data were related to clinical characteristics and functional imaging markers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ehjci/jez068DOI Listing

Impact of left ventricular pacing threshold on ventricular arrhythmia occurrence in cardiac resynchronization therapy.

J Cardiol 2019 Apr 13. Epub 2019 Apr 13.

Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia. Electronic address:

Background: Cardiac resynchronization therapy (CRT) is an established heart failure (HF) treatment option, however its effect on ventricular arrhythmias (VAs) is controversial. Regional scar burden and high left ventricular (LV) pacing threshold (PT) are associated with poor outcome in CRT patients. The aim of our study was to analyze the impact of intraoperative LVPT on VA occurrence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jjcc.2019.03.015DOI Listing

Increased QT and P-wave dispersion during attack-free period in pediatric patients with migraine attacks.

Cardiol Young 2019 Apr 17:1-4. Epub 2019 Apr 17.

Department of Pediatric Neurology,Medeniyet University Faculty of Medicine,Istanbul,Turkey.

Introduction: Migraine is a common neurovascular disease characterised with recurrent attacks by pain-free periods. It has been suggested that both sympathetic and parasympathetic dysfunctions play a role in its pathophysiology.

Aim: The aim of our study was to investigate the ECG changes during attack-free period in children with migraine, in terms of QTc interval, QTc, and P-wave dispersion to evaluate the autonomic nervous system disturbance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1047951119000088DOI Listing

Effect of Remote Ischemic Preconditioning on Complications After Elective Abdominal Aortic Aneurysm Repair: A Meta-Analysis With Randomized Control Trials.

Vasc Endovascular Surg 2019 Apr 16:1538574419840878. Epub 2019 Apr 16.

1 Department of Vascular Surgery, General Hospital of People's Liberation Army, Beijing, China.

Objective: This meta-analysis was to evaluate the effect of remote ischemic preconditioning (RIP) on complications after abdominal aortic aneurysm repair.

Methods: A literature search was conducted in Google scholar, PubMed, Embase, and Web of Science databases up to February 2019. The pooled risk difference (RD) as well as their 95% confidence interval (CI) were calculated by RevMan 5. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1538574419840878DOI Listing
April 2019
1 Read

Association between depression and the risk of developing ventricular arrhythmias: A meta-analysis
.

Int J Clin Pharmacol Ther 2019 Apr 16. Epub 2019 Apr 16.

Background: This meta-analysis aims to clarify the effects of depression on the risk of ventricular arrhythmias.

Materials And Methods: A systematic search was performed in PubMed, EMBASE, Web of Science, and the Cochrane Library. Summary hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated employing random-effects models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5414/CP203311DOI Listing
April 2019
1 Read

Clinical effects of intravenous to oral amiodarone transition strategies in critically ill adult patients.

J Clin Pharm Ther 2019 Apr 15. Epub 2019 Apr 15.

Department of Pharmacy, NYU Langone Health, New York, New York.

What Is Known And Objective: There is limited guidance on how to transition critically ill patients from intravenous (IV) to oral (PO) amiodarone. The objective of this study was to assess the impact of IV and PO amiodarone overlap on short-term tachyarrhythmia recurrence and adverse hemodynamic outcomes in the intensive care unit.

Methods: This is a retrospective, single-center analysis of critically ill adults who were treated with IV amiodarone for a supraventricular arrhythmia with rapid ventricular rate (RVR) and transitioned to PO amiodarone while inpatient. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jcpt.12841DOI Listing

Role of concealed conduction and allied phenomena in the genesis, maintenance, and termination of cardiac arrhythmias.

Pacing Clin Electrophysiol 2019 Apr 16. Epub 2019 Apr 16.

Heart and Vascular Team, Bellin Health, 744 South Webster Ave, Green Bay, Wisconsin, 54305.

Concealed conduction is a common electrocardiographic phenomenon whereby a series of events may occur as a result of incomplete propagation of an impulse. The occurrence, maintenance, and resolution (termination) of several events such as functional block and cardiac arrhythmias are linked to concealed conduction. This phenomenon should be suspected on the surface ECG whenever an arrhythmic event occurs unexpectedly. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pace.13699DOI Listing

Comparing the incidence of ventricular arrhythmias during epicardial ablation in swine vs. canine models.

Pacing Clin Electrophysiol 2019 Apr 15. Epub 2019 Apr 15.

International Clinical Research Center, St. Anne's University Hospital Brno, Pekařská 53, 656 91, Brno, Czech Republic.

Background: Choosing the appropriate animal model for development of novel technologies requires an understanding of anatomy and physiology of these different models. There is little data about the characteristics of different animal models for the study of technologies used for epicardial ablation. We aimed to compare the incidence of ventricular arrhythmias during epicardial radiofrequency ablation between swine and canine models using novel epicardial ablation catheters. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pace.13698DOI Listing
April 2019
1 Read

Morning Surge and Peak Morning Ambulatory Blood Pressure Versus Automated Office Blood Pressure in Predicting Cardiovascular Disease.

High Blood Press Cardiovasc Prev 2019 Apr 15. Epub 2019 Apr 15.

Department of Cardiology, Georgetown University and Veterans Affairs Medical Center, Athens, Greece.

Introduction: Automated office blood pressure (AOBP) has been recently shown to predict equally well to ambulatory blood pressure (ABP), conventional office blood pressure (OBP) and home blood pressure (HBP), cardiovascular (CV) events among hypertensives.

Aim: To compare AOBP recording and ABP monitoring in order to evaluate morning blood pressure (BP) peak in predicting CV events and deaths in hypertensives.

Methods: We assessed 236 initially untreated hypertensives, examined between 2009 and 2013. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s40292-019-00315-7
Publisher Site
http://dx.doi.org/10.1007/s40292-019-00315-7DOI Listing
April 2019
2 Reads

Virtual Care 2.0-a Vision for the Future of Data-Driven Technology-Enabled Healthcare.

Curr Treat Options Cardiovasc Med 2019 Apr 15;21(5):21. Epub 2019 Apr 15.

Department of Medicine, Divisions of General Internal Medicine and Biomedical Informatics, Chief Medical Information Officer of Population Health, University of California San Diego, 9560 Towne Centre Drive, San Diego, CA, 92121, USA.

A busy community cardiologist finished reading eight echocardiograms over lunch and started clinic at 1 pm. As three patients waited, "Jane," a 45-year-old graphic designer was seen for "skipped heart beat." She works about 50 h a week, exercises at the local gym, and enjoys eating a healthy diet. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11936-019-0727-2
Publisher Site
http://dx.doi.org/10.1007/s11936-019-0727-2DOI Listing
April 2019
1 Read

[Device-device interaction].

Herzschrittmacherther Elektrophysiol 2019 Apr 15. Epub 2019 Apr 15.

Med. Klinik I, Abteilung für Kardiologie und Angiologie, Universitätsklinik Gießen, UKGM, Klinikstraße 33, 35392, Gießen, Deutschland.

With a continuous increase in the approval of cardiac implantable electronic devices (CIED), not only pacemakers (PM) and implantable cardioverter defibrillators (ICD) but especially devices for treating chronic heart failure, more and more possibilities of device-device interactions arise, which in isolated cases can lead to death of the patient. Because of the still low numbers of patients overall, there are very few scientific studies and only isolated case reports on this topic. Devices which are at risk of interaction with a previously implanted PM are wearable cardioverter defibrillators (WCD) and subcutaneous ICDs (S-ICD). Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00399-019-0617-z
Publisher Site
http://dx.doi.org/10.1007/s00399-019-0617-zDOI Listing
April 2019
1 Read

Mutation-specific peripheral and ER quality control of hERG channel cell-surface expression.

Sci Rep 2019 Apr 15;9(1):6066. Epub 2019 Apr 15.

Department of Physiology, McGill University, Montréal, H3G 1Y6, Québec, Canada.

Impaired functional plasma membrane (PM) expression of the hERG K-channel is associated with Long-QT syndrome type-2 (LQT2) and increased risk of cardiac arrhythmia. Reduced PM-expression is primarily attributed to retention and degradation of misfolded channels by endoplasmic reticulum (ER) protein quality control (QC) systems. However, as the molecular pathogenesis of LQT2 was defined using severely-misfolded hERG variants with limited PM-expression, the potential contribution of post-ER (peripheral) QC pathways to the disease phenotype remains poorly established. Read More

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-019-42331-6
Publisher Site
http://dx.doi.org/10.1038/s41598-019-42331-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465299PMC
April 2019
1 Read

On cancer and atrial fibrillation: Nuances and limitations.

Authors:
Marc Sorigue

Eur J Intern Med 2019 04;62:e22-e23

Hematology Laboratory, ICO-Hospital Germans Trias i Pujol, Institut de Recerca Josep Carreras, Universitat Autònoma de Barcelona, Badalona, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejim.2018.11.010DOI Listing
April 2019
1 Read

Unique electrocardiographic pattern "w" wave in lead I of idiopathic ventricular arrhythmias arising from the distal great cardiac vein.

BMC Cardiovasc Disord 2019 Apr 15;19(1):90. Epub 2019 Apr 15.

Cardiovascular Department, Guangdong Cardiovascular Institute, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, 510010, Guangdong, China.

Background: The ECG characteristics of the distal coronary venous system ventricular arrhythmias (VAs) share common features with VAs arising from the aortic cusps or the endocardial left ventricular outflow tract (LVOT) beneath the cusps. The purpose of this study was to identify specific electrocardiographic and electrophysiological characteristics of VAs originating from the distal great cardiac vein (GCV).

Methods: Based on the successful ablation site, patients with idiopathic VAs from the distal GCV, left coronary cusp (LCC) or the subvalvular left ventricular outflow tract (LVOT) area were included in the present study. Read More

View Article

Download full-text PDF

Source
https://bmccardiovascdisord.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s12872-019-1064-9DOI Listing
April 2019
1 Read

Cardiac arrhythmias secondary to hormone therapy in trans women.

Expert Rev Cardiovasc Ther 2019 Apr 15. Epub 2019 Apr 15.

b Division of Cardiology, Kingston Health Science Center , Queen's University , Kingston , Ontario , Canada.

Introduction: With greater social acceptance and the evolution of transgender medicine as a specialty, more trans women are seeking hormone therapy (HT). Several studies have identified an increase in cardiovascular disease in trans women, however no studies have investigated the incidence of arrhythmias. Using two cases from the authors' clinic as examples, we propose that hormone therapy in trans women may increase the risk of cardiac arrhythmias. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14779072.2019.1
Publisher Site
http://dx.doi.org/10.1080/14779072.2019.1606713DOI Listing
April 2019
1 Read

Reducing False Arrhythmia Alarms Using Different Methods of Probability and Class Assignment in Random Forest Learning Methods.

Sensors (Basel) 2019 Apr 2;19(7). Epub 2019 Apr 2.

Department of Informatics, Faculty of Applied Informatics and Mathematics, Warsaw University of Life Sciences SGGW, 02-776 Warsaw, Poland.

The literature indicates that 90% of clinical alarms in intensive care units might be false. This high percentage negatively impacts both patients and clinical staff. In patients, false alarms significantly increase stress levels, which is especially dangerous for cardiac patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/s19071588DOI Listing
April 2019
1 Read

Electrically-Induced Ventricular Fibrillation Alters Cardiovascular Function and Expression of Apoptotic and Autophagic Proteins in Rat Hearts.

Int J Mol Sci 2019 Apr 2;20(7). Epub 2019 Apr 2.

Department of Pharmacology, Faculty of Pharmacy, University of Debrecen, 4032 Debrecen, Hungary.

Background: The pathological heart contractions, called arrhythmias, especially ventricular fibrillation (VF), are a prominent feature of many cardiovascular diseases leading to sudden cardiac death. The present investigation evaluates the effect of electrically stimulated VF on cardiac functions related to autophagy and apoptotic mechanisms in isolated working rat hearts.

Methods: Each group of hearts was subjected to 0 (Control), 1, 3, or 10 min of spacing-induced VF, followed by 120 min of recovery period and evaluated for cardiac functions, including aortic flow (AF), coronary flow (CF), cardiac output (CO), stroke volume (SV), and heart rate (HR). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20071628DOI Listing

Influenza A (H1N1) pdm09 virus infection in a patient with incomplete Kawasaki disease: A case report.

Medicine (Baltimore) 2019 Apr;98(15):e15009

Department Second of Infectious Diseases.

Rationale: Kawasaki disease (KD) is a vasculitic illness of childhood associated with coronary artery dilatation, coronary artery aneurysm, arrhythmia, sudden death, and other serious cardiovascular diseases. Up to date, the etiology of KD remains unclear; however, epidemiological characteristics indicate that it may be related to as-yet-undefined pathogen infection.

Patient Concerns: A 19-month-old boy had a fever of unknown origin at 38°C for 9 days without rash, runny nose and cough. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000015009DOI Listing
April 2019
2 Reads

Gastrointestinal and liver diseases and atrial fibrillation: a review of the literature.

Therap Adv Gastroenterol 2019 2;12:1756284819832237. Epub 2019 Apr 2.

Evans Department of Medicine, Boston University School of Medicine, Boston, MA, USA.

Atrial fibrillation (AF) is the most common arrhythmia worldwide and is associated with significant morbidity and mortality. A number of risk factors have been associated with AF, though few studies have explored the association between gastrointestinal and liver diseases and AF. Additionally, AF and treatment for AF may predispose to gastrointestinal and liver diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1756284819832237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448121PMC
April 2019
1 Read