2,020 results match your criteria Arquivos de gastroenterologia[Journal]


VALUE OF CLINICAL, LABORATORY PARAMETERS AND ANALYSIS OF RETINAL VASCULARIZATION IN PEDIATRIC PATIENTS WITH PORTAL HYPERTENSION.

Arq Gastroenterol 2020 Apr-Jun;57(2):121-125

Universidade Federal de São Paulo, Departamento de Oftalmologia e Ciências Visuais, Divisão de Retina e Vítreo, São Paulo, SP, Brasil.

Background: Portal hypertension is one of the complications of cirrhosis and is associated with numerous systemic manifestations, including renal, brain, pulmonary, cardiac and vascular changes. In routine ophthalmological examinations performed at our service, we observed that some children diagnosed with portal hypertension had increased retinal vascular tortuosity.

Objective: 1. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-41DOI Listing

UNDERWATER ENDOSCOPIC MUCOSAL RESECTION FOR NON-PEDUNCULATED COLORECTAL LESIONS. A PROSPECTIVE SINGLE-ARM STUDY.

Arq Gastroenterol 2020 Apr-Jun;57(2):193-197

Universidade de São Paulo, Faculdade de Medicina, Departamento de Gastroenterologia, Instituto do Câncer do Estado de São Paulo, São Paulo, SP, Brasil.

Background: Underwater endoscopic mucosal resection (UEMR) has emerged as a revolutionary method allowing resection of colorectal lesions without submucosal injection. Brazilian literature about this technique is sparse.

Objective: The aim of this study was evaluate the efficacy and safety of UEMR technique for removing non-pedunculated colorectal lesions in two Brazilian tertiary centers. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-37DOI Listing
January 2020

PREVALENCE AND FACTORS ASSOCIATED WITH CONSTIPATION IN PREMENOPAUSAL WOMEN: A COMMUNITY-BASED STUDY.

Arq Gastroenterol 2020 Apr-Jun;57(2):188-192

Universidade Federal do Rio Grande do Norte, Faculdade de Ciências da Saúde de Trairi (FACISA), Santa Cruz, RN, Brasil.

Background: Intestinal constipation is characterized by problems related to evacuation, and presents high prevalence in the female gender. This condition has demonstrated negative effects on the development of daily activities, causing damage to the physical and emotional well-being of individuals who are diagnosed with it. Studies that investigate what health impairments intestinal constipation can cause are scarce in the literature. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-36DOI Listing
January 2020

HOSPITAL MORBIDITY AND COLORECTAL CANCER MORTALITY: IMPLICATIONS FOR PUBLIC HEALTH IN BRAZIL.

Arq Gastroenterol 2020 Apr-Jun;57(2):182-187

Instituto de Ensino e Pesquisa do Hospital Sírio Libanês (IEP-HSL), São Paulo, SP, Brasil.

Background: Colorectal cancer is a serious public health problem and one of the most common cancer worldwide. Countries around the world have shown different trends. While incidence and mortality rates for colorectal cancer are on an upward trend in developing countries, these rates have been on a downward trend in most developed countries. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-34DOI Listing
January 2020

PORTUGUESE VERSION OF THE SNAQ QUESTIONNAIRE: TRANSLATION AND CULTURAL ADAPTATION.

Arq Gastroenterol 2020 Apr-Jun;57(2):178-181

Universidade de São Paulo, Faculdade de Saúde Pública, São Paulo, SP, Brasil.

Background: Poor appetite is common through the aging process and increases the risk of weight loss, protein-energy malnutrition, immunossupression, sarcopenia and frailty. The Simplified Nutritional Appetite Questionnaire (SNAQ) has the aim to monitor appetite and identify older adults at risk of weight loss.

Objective: To describe the process of translation and cultural adaptation to Brazilian Portuguese of the SNAQ. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-33DOI Listing
December 2019

BOWEL FREQUENCY AND SYMPTOMS OF CONSTIPATION AND ITS RELATION WITH THE LEVEL OF PHYSICAL ACTIVITY IN PATIENTS WITH CHAGAS DISEASE.

Arq Gastroenterol 2020 Apr-Jun;57(2):161-166

Universidade Estadual de Maringá, Departamento de Ciências Básicas da Saúde, Parasitologia, Maringá, PR, Brasil.

Background: Intestinal constipation (IC) in patients with the digestive form of Chagas disease is one of the main reasons for seeking medical care. Population data indicate that the practice of physical activity improves gastrointestinal motility.

Objective: This study evaluated the bowel frequency and symptoms of constipation and their relationship with the level of physical activity in patients with and without Chagas disease. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-30DOI Listing
December 2019

DIAGNOSTIC ACCURACY OF GASTROPANEL® FOR ATROPHIC GASTRITIS IN BRAZILIAN SUBJECTS AND THE EFFECT OF PROTON PUMP INHIBITORS.

Arq Gastroenterol 2020 Apr-Jun;57(2):154-160

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Divisão de Endoscopia, São Paulo, SP, Brasil.

Background: It has been proposed that the combination of gastrin-17 (G-17), pepsinogens I and II (PGI and PGII), and anti-Helicobacter pylori (H. pylori) antibodies (GastroPanel®, BIOHIT HealthCare, Helsinki, Finland) could serve as biomarkers of atrophic gastritis.

Objective: This study aimed to ensure the diagnostic accuracy of GastroPanel® and evaluate the effect of proton pump inhibitors (PPIs) on these biomarkers. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-29DOI Listing
November 2019

ORAL AND PHARYNGEAL TRANSIT IN FUNCTIONAL HEARTBURN.

Arq Gastroenterol 2020 Apr-Jun;57(2):150-153

Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Clínica Médica, Ribeirão Preto, SP, Brasil.

Background: Gastroesophageal reflux disease is associated with slower transit of the bolus through the pharynx and upper esophageal sphincter. Functional heartburn has similar symptoms to gastroesophageal reflux disease, however, the symptoms are not caused by reflux.

Objective: The aim of this investigation was to evaluate oral and pharyngeal transit in patients with functional heartburn, with the hypothesis that, similar to patients with gastroesophageal reflux disease, they have changes in pharyngeal and upper esophageal sphincter transit time. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-28DOI Listing
November 2019

PATTERNS OF FIBER INTAKE AMONG BRAZILIAN ADULTS: PERCEPTIONS FROM AN ONLINE NATIONWIDE SURVEY.

Arq Gastroenterol 2020 Apr-Jun;57(2):144-149

Takeda Pharmaceuticals Brazil, São Paulo, SP, Brasil.

Background: Adequate fiber intake is associated with digestive health and reduced risk of several noncommunicable diseases and is recognized as essential for human health (World Health Organization, 2003). The World Health Organization (WHO) recommends a daily fiber consumption of ≥25 g, but previous studies observed a fiber intake in Brazil lower than recommended.

Objective: We aimed to describe fiber intake among adults in Brazil and also respondents' knowledge and perceptions about their fiber intake. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-26DOI Listing
October 2019

ASSOCIATION BETWEEN DIABETICS AND INTESTINAL CANCER WITH THE RISK OF MUTATION IN CD38 GENE IN IRANIAN POPULATION.

Arq Gastroenterol 2020 Apr-Jun;57(2):137-143

Islamic Azad University, Faculty of Biological Sciences, Department of Genetics, Tonekabon Branch, Iran.

Background: Intestinal cancer often occurs in type 2 diabetic patients. The concept of increasing insulin levels and insulin-like growth factor in the blood with type 2 diabetes are stimulated with the growth and depletion of cloned cell walls, and the continuation of this process leads to the cellular deformation. This is the evidence for intestinal cancer in type 2 diabetes in population. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-25DOI Listing
October 2019

MOLAR INCISOR HYPOMINERALIZATION AND CELIAC DISEASE.

Arq Gastroenterol 2020 Apr-Jun;57(2):167-171

Universidade Federal do Paraná, Curitiba, PR, Brasil.

Background: Molar incisor hypomineralization (MIH) is a developmental enamel defect with multifactorial etiology. Although the relationship between celiac disease (CD) and developmental enamel defect was demonstrated, the association between CD and MIH is uncertain.

Objective: The objective of this study was to analyze the occurrence of MIH in CD patients. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-31DOI Listing
December 2019

PANCREATIC STEATOSIS: A NEW DIAGNOSIS AND THERAPEUTIC CHALLENGE IN GASTROENTEROLOGY.

Arq Gastroenterol 2020 Apr-Jun;57(2):216-220

University Hospital of North Cumbria, Department of Gastroenterology, UK.

Fat infiltration in the pancreas is called pancreatic steatosis and it has several synonyms such as pancreatic lipomatosis, non-alcoholic fatty pancreatic disease, lipomatous pseudohypertrophy, fatty replacement, fatty pancreas and fatty infiltration. Pancreatic steatosis describes a disease ranging from infiltration of fat in the pancreas to pancreatic inflammation, and development of pancreatic fibrosis. There are multiple aetiologies of this condition, such as metabolic syndrome, alcohol intake, viral infections, toxins, congenital syndromes, etc. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-27DOI Listing
October 2019

NUTRITIONAL STATUS, QUALITY OF LIFE AND LIFE HABITS OF WOMEN WITH IRRITABLE BOWEL SYNDROME: A CASE-CONTROL STUDY.

Arq Gastroenterol 2020 Apr-Jun;57(2):114-120

Universidade de Campinas (UNICAMP), Faculdade de Ciências Aplicadas, Campinas, SP, Brasil.

Background: Irritable bowel syndrome is a functional and chronic gastrointestinal disorder that may cause abdominal pain and altered bowel habits, affecting the nutritional status and quality of life of its carriers. Its prevalence is high, affecting about 10% to 15% of the general population in developed countries, being more prevalent in women than in men in the proportion 2:1.

Objective: The aim of our study was to compare the profile of body adiposity, life habits, and the quality of life of women with irritable bowel syndrome with a healthy control group. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-22DOI Listing

BLADDER AND BOWEL DYSFUNCTION IN MOTHERS AND CHILDREN: A POPULATION-BASED CROSS-SECTIONAL STUDY.

Arq Gastroenterol 2020 Apr-Jun;57(2):126-130

Escola Bahiana de Medicina e Saúde Pública (BAHIANA), Centro de Distúrbios Miccionais na Infância (CEDIMI), Salvador, BA, Brasil.

Background: Recently it was shown an association between lower urinary tract symptoms in mothers and their children. However, the role of functional constipation in this binomial is unclear.

Objective: To evaluate bladder and bowel dysfunction between mothers and children. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-23DOI Listing
September 2019

OUTLET OBSTRUCTED CONSTIPATION AND FECAL INCONTINENCE: IS REHABILITATION TREATMENT THE WAY? MYTH OR REALITY.

Arq Gastroenterol 2020 Apr-Jun;5757(2):198-202

University of Campania "Luigi Vanvitelli", Division of General, Mininvasive and Bariatric Surgery, Naples, Italy.

Pelvic floor rehabilitation aims to address perineal functional and anatomic alterations as well as thoraco-abdominal mechanic dysfunctions leading to procto-urologic diseases like constipation, fecal and urinary incontinence, and pelvic pain. They require a multidimensional approach, with a significant impact on patients quality of life. An exhaustive clinical and instrumental protocol to assess defecation disorders should include clinical and instrumental evaluation as well as several clinical/physiatric parameters. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-38DOI Listing
February 2020

CLINICAL EVALUATION AND PATTERN OF SYMPTOMS IN COLORECTAL CANCER PATIENTS.

Arq Gastroenterol 2020 Apr-Jun;57(2):131-136

Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil.

Background: Colorectal cancer is the third most common type of cancer in the world and the increased survival of the colorectal cancer population is very significant. Thus, it becomes relevant to study the symptoms associated with the progression of the disease and treatment, for proper clinical management.

Objective: To describe the clinical and epidemiological profile of colorectal cancer patients and to identify the most prevalent signs and symptoms patterns. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-24DOI Listing
October 2019

NORMAL VALUES OF ESOPHAGEAL HIGH-RESOLUTION MANOMETRY: A BRAZILIAN MULTICENTER STUDY.

Arq Gastroenterol 2020 Apr-Jun;57(2):209-215

Universidade de São Paulo, Faculdade de Medicina, Departamento de Gastroenterologia São Paulo, SP, Brasil.

Background: The high-resolution manometry has been a significant advance in esophageal diagnostics. There are different types of catheter and systems devices to capture esophageal pressures that generate variable data related to Chicago Classification (CC) and consequently influence normal values results. There are not normative data for the 24-channel water-perfused high-resolution manometry system most used in Brazil with healthy volunteers in supine posture. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-40DOI Listing

DUODENAL DUPLICATION CYST WITH ENTEROLITHS DIAGNOSED BY ECHOENDOSCOPY AND TREATED BY ENDOSCOPIC MARSUPIALIZATION.

Arq Gastroenterol 2020 Jan-Mar;57(1):110-111

Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Cirurgia e Anatomia; HCFMRP-USP, Ribeirão Preto, SP, Brasil.

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http://dx.doi.org/10.1590/S0004-2803.202000000-19DOI Listing

REPRODUCTIVE ASPECTS IN BRAZILIAN CELIAC WOMEN.

Arq Gastroenterol 2020 Jan-Mar;57(1):107-109

Universidade Federal do Paraná, Hospital de Clínicas, Curitiba, PR, Brasil.

Background: Celiac disease (CD) is a chronic enteropathy in response to ingestion of gluten. CD was associated with gynecological disorders.

Objective: In this retrospective study, we aimed to investigate the age of menarche, age of menopause, number of pregnancies and abortions in Brazilian celiac patients. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-18DOI Listing

DIAGNOSTIC AND MANAGEMENT APPROACH TO POUCHITIS IN INFLAMMATORY BOWEL DISEASE.

Arq Gastroenterol 2020 Jan-Mar;57(1):100-106

Clínica Las Condes, Gastroenterology Department, Inflammatory Bowel Disease Program, Santiago, Chile.

In patients with ulcerative colitis refractory to medical therapy, total proctocolectomy and posterior ileal-anal pouch anastomosis is the standard surgical therapy. One of the possible complications is pouchitis. Depending on the duration of the symptoms, it can be classified as acute, recurrent, or chronic. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-17DOI Listing

ASSOCIATION OF IL-8 -251T>A (RS4073) POLYMORPHISM WITH SUSCEPTIBILITY TO GASTRIC CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS BASED ON 33 CASE-CONTROL STUDIES.

Arq Gastroenterol 2020 Jan-Mar;57(1):91-99

Shahid Sadoughi University of Medical Sciences, Department of Medical Genetics, Yazd, Iran.

Background: The role of -251A>T polymorphism in the anti-inflammatory cytokine interleukin-8 (IL-8) gene in gastric cancer was intensively evaluated, but the results of these studies were inconsistent.

Objective: Therefore, we performed a meta-analysis to provide a comprehensive data on the association of IL-8 -251T>A polymorphism with gastric cancer.

Methods: All eligible studies were identified in PubMed, Web of Science, EMBASE, Wanfang and CNKI databases before September 01, 2019. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-16DOI Listing

PLACEBO USE IN THE CONTEXT OF INFLAMMATORY BOWEL DISEASE CLINICAL TRIALS.

Arq Gastroenterol 2020 Jan-Mar;57(1):87-90

CEMIC, Gastroenterology Department, Buenos Aires, Argentina.

Inflammatory bowel disease comprises two distinct conditions - Crohn's disease and ulcerative colitis - which can be treated with immunomodulators. A non-neglectable proportion of these patients will need biologic therapy, and many patients under biologic treatment will experience either primary or secondary failure. As a consequence, clinical trials evaluating new therapeutic alternatives are being developed. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-15DOI Listing

PERORAL (POEM) OR SURGICAL MYOTOMY FOR THE TREATMENT OF ACHALASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Arq Gastroenterol 2020 Jan-Mar;57(1):79-86

Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Unidade de Endoscopia, Departamento de Gastroenterologia, São Paulo, SP, Brasil.

Background: Achalasia is a neurodegenerative motility esophageal disorder characterized by failure of lower esophageal sphincter relaxation. The conventional treatment option for achalasia has been laparoscopic Heller myotomy (LHM). However, in 2010, Inoue et al. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-14DOI Listing

ASSOCIATION OF DUODENAL EOSINOPHILIC INFILTRATE WITH HELICOBACTER PYLORI INFECTION, BUT NOT WITH FUNCTIONAL DYSPEPSIA.

Arq Gastroenterol 2020 Jan-Mar;57(1):74-78

Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Pós-Graduação em Ciências em Gastroenterologia e Hepatologia, Porto Alegre, RS, Brasil.

Background: The role of Helicobacter pylori infection on eosinophilic infiltration in duodenal mucosa is poorly studied. An increase in the number of eosinophils in duodenum has been associated with functional dyspepsia.

Objective: To evaluate the influence of H. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-13DOI Listing

SEROCONVERSION ANALYSIS AFTER HABITUAL HEPATITIS B VACCINATION SCHEME IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES.

Arq Gastroenterol 2020 Jan-Mar;57(1):69-73

UNIVALI, Unidade de Saúde da Família e Comunidade, Clínica Interdisciplinar de Doença Inflamatória Intestinal, Itajaí, SC, Brasil.

Background: Patients with inflammatory bowel disease (IBD) vaccinated for hepatitis B have a low success rate in achieving protective antibody levels. The main factors suggested for this are IBD itself and the use of immunosuppressive drugs.

Objective: To evaluate the concentration of anti-HBs antibodies and to verify factors associated with the effectiveness of hepatitis B vaccination in patients with IBD. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-12DOI Listing

RESPIRATORY AND SYMPTOMATIC IMPACT OF ASCITES RELIEF BY PARACENTESIS IN PATIENTS WITH HEPATIC CIRRHOSIS.

Arq Gastroenterol 2020 Jan-Mar;57(1):64-68

Universidade Federal do Espírito Santo, Departamento de Educação Integrada em Saúde, Vitória, ES, Brasil.

Background: Liver cirrhosis is a highly prevalent disease that, at an advanced stage, usually causes ascites and associated respiratory changes. However, there are few studies evaluating and quantifying the impact of ascites and its relief through paracentesis on lung function and symptoms such as fatigue and dyspnea in cirrhotic patients.

Objective: To assess and quantify the impact of acute reduction of ascitic volume on respiratory parameters, fatigue and dyspnea symptoms in patients with hepatic cirrhosis, as well as to investigate possible correlations between these parameters. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-11DOI Listing

THE INFLAMMATORY BOWEL DISEASE-FATIGUE PATIENT SELF-ASSESSMENT SCALE: TRANSLATION, CROSS-CULTURAL ADAPTATION AND PSYCHOMETRIC PROPERTIES OF THE BRAZILIAN VERSION (IBD-F BRAZIL).

Arq Gastroenterol 2020 Jan-Mar;57(1):50-63

Universidade Federal de Juiz de Fora, Programa de Pós-graduação em Ciências da Reabilitação e Desempenho Físico-Funcional, MG, Brasil.

Background: Fatigue is a common symptom in patients with inflammatory bowel diseases (IBD). A translated and culturally adapted, instrument with robust psychometric for measuring fatigue in Brazilian patients with IBD is needed.

Objective: To translate and cross-culturally adapt the inflammatory Bowel Disease Fatigue Scale (IBD-F) into Brazilian-Portuguese and to test its measurement properties in Brazilian patients with IBD. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-10DOI Listing

HEPATITIS C TREATMENT OF RENAL TRANSPLANT AND CHRONIC KIDNEY DISEASE PATIENTS: EFFICACY AND SAFETY OF DIRECT-ACTING ANTIVIRAL REGIMENS CONTAINING SOFOSBUVIR.

Arq Gastroenterol 2020 Jan-Mar;57(1):45-49

Universidade Federal de São Paulo (UNIFESP), Disciplina de Gastroenterologia, São Paulo, SP, Brasil.

Background: Direct-acting antivirals have revolutionized hepatitis C treatment, also for patients with chronic kidney disease (CKD), but some controversy exists regarding the use of sofosbuvir (SOF) in patients with glomerular filtration rate (GFR) <30 mL/min.

Objective: To evaluate the efficacy and safety of these regimens for hepatitis C treatment of patients with CKD and after renal transplantation, as well as the impact of SOF on renal function in non-dialysis patients.

Methods: All patients with hepatitis C and CKD or renal transplant treated with direct-acting antivirals at a referral center in Brazil between January 2016 and August 2017 were included. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-09DOI Listing

COMBINED NS5A & NS5B NUCLEOTIDE INHIBITOR THERAPY FOR PATIENTS WITH CHRONIC HEPATITIS C WITH STAGE 5 CHRONIC KIDNEY DISEASE ON HEMODIALYSIS.

Arq Gastroenterol 2020 Jan-Mar;57(1):39-44

T.N.M.C & B.Y.L Nair Charitable Hospital, Gastroenterology, Mumbai, India.

Background: Hepatitis C virus (HCV) infection is the most common hepatotropic viral infection affecting the patients on maintenance hemodialysis. Treatment of chronic HCV infection in stage 4 and 5 CKD includes a combination of elbasvir/grazoprevir and glecaprevir/pibrentasvir, which are not available in many countries.

Objective: Hence, we have conducted this study to look for the safety and efficacy of sofosbuvir combination therapy in this difficult to treat population. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-08DOI Listing

EVALUATION AND SELECTION OF CANDIDATES FOR LIVER TRANSPLANTATION: AN ECONOMIC PERSPECTIVE.

Arq Gastroenterol 2020 Jan-Mar;57(1):31-38

Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Programa de Graduação em Medicina, Porto Alegre, RS, Brasil.

Background: Over the next 20 years, the number of patients on the waiting list for liver transplantation (LTx) is expected to increase by 23%, while pre-LTx costs should raise by 83%.

Objective: To evaluate direct medical costs of the pre-LTx period from the perspective of a tertiary care center.

Methods: The study included 104 adult patients wait-listed for deceased donor LTx between October 2012 and May 2016 whose treatment was fully provided at the study transplant center. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-07DOI Listing

EFFECTS OF SYNBIOTIC SUPPLEMENTATION ON GUT FUNCTIONING AND SYSTEMIC INFLAMMATION OF COMMUNITY-DWELLING ELDERS - SECONDARY ANALYSES FROM A RANDOMIZED CLINICAL TRIAL.

Arq Gastroenterol 2020 Jan-Mar;57(1):24-30

Universidade de São Paulo, Faculdade de Saúde Pública, Departamento de Nutrição, São Paulo, SP, Brasil.

Background: Aging is a complex process marked by alterations on gut functioning and physiology, accompanied by an increase on the inflammatory status, leading to a scenario called "inflammaging".

Objective: To evaluate the effects of a synbiotic substance on systemic inflammation, gut functioning of community-dwelling elders.

Methods: This is a secondary analysis from a randomized clinical trial, lasting 24 weeks, including 49 elders, distributed into two groups: SYN (n=25), which received a synbiotic substance (Frutooligossacaride 6g, Lactobacillus paracasei LPC-31 109 to 108 UFC, Lactobacillus rhamnosus HN001 109 to 108 UFC, Lactobacillus acidophilus NCFM 109 to 108 UFC e Bifidobacterium lactis HN019 109 to 108 UFC), or PLA (n=24), receiving placebo. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-06DOI Listing

HEPATOCELLULAR CARCINOMA PATIENTS ARE ADVANTAGED IN THE CURRENT BRAZILIAN LIVER TRANSPLANT ALLOCATION SYSTEM. A COMPETING RISK ANALYSIS.

Arq Gastroenterol 2020 Jan-Mar;57(1):19-23

Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Faculdade de Medicina, Programa de Pós-Graduação em Medicina, Hepatologia, Porto Alegre, RS, Brasil.

Background: In Brazil, the Model for End-Stage Liver Disease (MELD) score is used to prioritize patients for deceased donor liver transplantation (DDLT). Patients with hepatocellular carcinoma (HCC) receive standardized MELD exception points to account for their cancer risk of mortality, which is not reflected by their MELD score.

Objective: To compare DDLT rates between patients with and without HCC in Rio Grande do Sul, the Southernmost state of Brazil. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-05DOI Listing

ASSESSMENT OF WEIGHT LOSS AFTER NON-ADJUSTABLE AND ADJUSTABLE INTRAGASTRIC BALLOON USE.

Arq Gastroenterol 2020 Jan-Mar;57(1):13-18

Usuy Clínica Médica, Florianópolis, SC, Brasil.

Background: Intragastric balloon (IGB) use is indicated for patients whose BMI precludes the option of bariatric surgery or who need to lose weight prior to undergoing surgery. It is a minimally invasive procedure and currently there are two main models of IGBs in use, the non-adjustable intragastric balloon (NIB), implanted for six months, and the adjustable intragastric balloon (AIB), implanted for up to 12 months.

Objective: Analyze clinical characteristics between patients receiving non-adjustable gastric balloon and the adjustable (prolonged implantation) intragastric balloon. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-04DOI Listing

QUALITY OF LIFE OF PATIENTS FROM A MULTIDISCIPLINARY CLINIC OF INFLAMMATORY BOWEL DISEASE.

Arq Gastroenterol 2020 Jan-Mar;57(1):8-12

UNIVALI, Departamento de Psicologia, Itajaí, SC, Brasil.

Background: Inflammatory bowel disease encompasses pathological entities, the main being Crohn's disease and ulcerative rectocolitis. Both are characterized by chronic inflammation of the intestine. It affects young people of active age, compromising the situation of those patients, especially their quality of life, experiencing a strong deterioration in their clinical condition, from physical to social and emotional aspects. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-03DOI Listing

QUALITY OF LIFE IN CAREGIVERS OF PEDIATRIC PATIENTS WITH CEREBRAL PALSY AND GASTROSTOMY TUBE FEEDING.

Arq Gastroenterol 2020 Jan-Mar;57(1):3-7

UNICAMP, Departamento de Pediatria, Campinas, SP, Brasil.

Background: Cerebral palsy is the most common cause of physical disability in childhood. Caregivers of patients presenting tetraparesis cerebral palsy (TCP) and gastrostomy tube feeding (GTF) were selected for this study because both conditions represent a great demand for their caregivers.

Objective: To describe the quality of life related to the state of health of caregivers of patients with TCP who were fed by gastrostomy, to assess the results linked to the mental health of these caregivers, to compare our data with data from other studies on children with cerebral palsy without gastrostomy and to evaluate the possible interference of gastrostomy in the quality of life. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-02DOI Listing

LIVER TRANSPLANTATION IN BRAZIL: THE URGENT NEED OF A NEW ALLOCATION SYSTEM FOR THE EXCEPTIONS IN MELD SCORE.

Arq Gastroenterol 2020 Jan-Mar;57(1):1-2

Universidade de São Paulo (HC FMUSP), Departamento de Gastroenterologia, Transplante de Órgãos do Aparelho Digestivo, São Paulo, SP, Brasil.

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http://dx.doi.org/10.1590/S0004-2803.202000000-01DOI Listing

BRAZILIAN SOCIETY OF HEPATOLOGY UPDATED RECOMMENDATIONS FOR DIAGNOSIS AND TREATMENT OF HEPATOCELLULAR CARCINOMA.

Arq Gastroenterol 2020 9;57(suppl 1):1-20. Epub 2020 Mar 9.

Universidade de São Paulo, Instituto do Câncer do Estado de São Paulo, São Paulo, SP, Brasil.

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. The Brazilian Society of Hepatology (SBH) published in 2015 its first recommendations about the management of HCC. Since then, new data have emerged in the literature, prompting the governing board of SBH to sponsor a single-topic meeting in August 2018 in São Paulo. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-20DOI Listing

HELICOBACTER PYLORI INFECTION AND GASTRIC CANCER PRECURSOR LESIONS: PREVALENCE AND ASSOCIATED FACTORS IN A REFERENCE LABORATORY IN SOUTHEASTERN BRAZIL.

Arq Gastroenterol 2019 Oct-Dec;56(4):419-424

Universidade Federal de Juiz de Fora, Departamento de Patologia, Juiz de Fora, MG, Brasil.

Background: Helicobacter pylori infection is the most important risk factor for gastric atrophy and intestinal metaplasia, both considered gastric cancer precursor lesions. Therefore, the investigation of the occurrence of H. pylori infection, precursor lesions and associated factors guides the adoption of specific strategies for the control this type of cancer. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-84DOI Listing
January 2020

RISK FACTORS ASSOCIATED WITH EARLY MORTALITY AFTER PERCUTANEOUS ENDOSCOPIC GASTROSTOMY IN PATIENTS AT A TERTIARY CARE CENTER IN BRAZIL: A RETROSPECTIVE SINGLE-CENTER SURVIVAL STUDY.

Arq Gastroenterol 2019 Oct-Dec;56(4):412-418

Universidade de Pernambuco, Faculdade de Ciências Médicas, Recife, PE, Brasil.

Background: Percutaneous endoscopic gastrostomy (PEG) is the main accepted method for long-term tube feeding.

Objective: To investigate the risk factors associated with early mortality after PEG.

Methods: Retrospective survival analysis in a tertiary-level center in Recife, Brazil. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-83DOI Listing
January 2020

QUERCETIN SUPPLEMENTATION PREVENTS CHANGES IN THE SEROTONIN AND CASPASE-3 IMMUNOREACTIVE CELLS OF THE JEJUNUM OF DIABETIC RATS.

Arq Gastroenterol 2019 Oct-Dec;56(4):405-411

Universidade Estadual de Maringá, Departamento de Ciências Morfológicas - Laboratório de Plasticidade Neural Entérica, Maringá, PR, Brasil.

Background: Serotonin (5-HT) is present in the epithelial enterochromaffin cells (EC), mast cells of the lamina propria and enteric neurons. The 5-HT is involved in regulating motility, secretion, gut sensation, immune system and inflammation.

Objective: Evaluate the effects of diabetes and quercetin supplementation on serotoninergic cells and its cell loss by apoptosis in jejunal mucosa of streptozotocin-induced diabetic rats (STZ-rats). Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-81DOI Listing
January 2020

STUDY OF LIPID BIOMARKERS OF PATIENTS WITH POLYPS AND COLORECTAL CÂNCER.

Arq Gastroenterol 2019 Oct-Dec;56(4):399-404

Universidade Federal de São Paulo, Disciplina de Gastroenterologia, Departamento de Medicina, São Paulo, SP, Brasil.

Background: Colorectal cancer (CRC) is one of the leading causes of cancer worldwide. Early diagnostic methods using serum biomarkers are required. The study of omics, most recently lipidomics, has the purpose of analyzing lipids for a better understanding of human lipidoma. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-80DOI Listing
January 2020

SUSTAINED VIROLOGIC RESPONSE RATE IN CHRONIC HEPATITIS C PATIENTS THROUGH DIRECT-ACTING ANTIVIRALS THERAPY.

Arq Gastroenterol 2019 Oct-Dec;56(4):394-398

Universidade Federal do Rio Grande (FURG), Faculdade de Medicina, Programa de Pós-Graduação em Ciências da Saúde. Rio Grande, RS, Brasil.

Background: In recent years the management of hepatitis C virus infection and the possibility of its eradication have been researched due to the importance that they represent in the health of the world population. Obtaining data that help to cope with this pathology improves the quality of life of those affected by it. The present study evaluated the effectiveness of direct-acting antiviral therapies provided by the Brazilian Ministry of Health in accordance to the Clinical Protocol and Therapeutic Guidelines of 2015. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-79DOI Listing
January 2020

ALTERED ESOPHAGEAL MOTILITY DURING PERCEPTION OF BOLUS TRANSIT IN HEALTHY VOLUNTEERS.

Arq Gastroenterol 2019 Oct-Dec;56(4):386-389

Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, SP, Brasil.

Background: The perception of bolus transit through the thoracic esophagus may be caused by altered esophageal anatomy and function.

Objective: To evaluate the hypothesis that, in healthy volunteers, swallows followed by perception of esophageal bolus transit are associated with changes in esophageal motility.

Methods: Simultaneous evaluation of motility and perception of esophageal bolus transit was performed in 22 healthy volunteers. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-78DOI Listing
January 2020

PROFILE OF HCV GENOTYPES AND HIV-SUBTYPES AMONG HIV-COINFECTED PATIENTS IN SOUTHERN BRAZIL.

Arq Gastroenterol 2019 Oct-Dec;56(4):344-350

Universidade Estadual de Maringá, Departamento de Análises Clínicas e Biomedicina, Maringá, PR, Brasil.

Background: Hepatitis B and C virus (HBV and HCV) are the two most common infections among human immunodeficiency virus (HIV)-infected patients.

Objective: To identify the frequency of HIV subtypes and HCV genotypes in HIV-coinfected patients.

Methods: A cross-sectional and retrospective study was carried out into two reference centers in Southern Brazil between January 1, 2002 and June 30, 2016. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-68DOI Listing
January 2020

An inevitable consequence.

Arq Gastroenterol 2019 Oct-Dec;56(4):331-332

Hospital IGESP, Motilidade Digestiva e Neurogastroenterologia (MoDiNe), São Paulo, SP, Brasil. ORCID: 0000-0002-6541-0401.

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http://dx.doi.org/10.1590/S0004-2803.201900000-61DOI Listing
February 2020

GENEXPERT FOR ABDOMINAL TUBERCULOSIS.

Authors:
Alka Sharma

Arq Gastroenterol 2019 Oct-Dec;56(4):454

Atal Bihari Vajpayee Institute of Medical Sciences and Dr RML Hospital, Department of Medicine, Delhi, India.

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http://dx.doi.org/10.1590/S0004-2803.201900000-82DOI Listing
February 2020

NEW IMMUNIZATION SCHEDULE EFFECTIVENESS AGAINST HEPATITIS B IN LIVER TRANSPLANTATION PATIENTS.

Arq Gastroenterol 2019 Oct-Dec;56(4):440-446

Fundação Faculdade Regional de Medicina de São José do Rio Preto / Hospital de Base - FUNFARME/FAMERP/HB, São José do Rio Preto, SP, Brasil.

Background: Although liver transplantation is considered to be a high-risk procedure, it is well-established as a treatment option for the cure and quality of life enhancement for individuals who suffer from diseases. Preventing an infection by hepatitis B virus through immunization schedules has been the most effective way to reduce complications, since it decreases the number of people who suffer from chronic hepatitis caused by the hepatitis B virus and eradicates its transmission.

Objective: 1. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-77DOI Listing
January 2020

PROSPECTIVE MONITORING OF DRUG USE: DRUG-INDUCED LIVER INJURY IN A PRIMARY HEALTHCARE CENTER.

Arq Gastroenterol 2019 Oct-Dec;56(4):390-393

UFBA, Faculdade de Medicina da Bahia, Salvador, BA, Brasil.

Background: Drug-induced liver injury is still misunderstood in Brazil due to diagnostic difficulties or lack of reporting incidents.

Objective: To assess the frequency of adverse events related to the use of medicines in a primary healthcare unit, in a city locate southwestern of the state of Bahia, Brazil.

Methods: Prospective study conducted at the Primary Center for Specialized Health (CEMEA), February at August of 2013 in Vitoria da Conquista, Bahia, Brazil. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-73DOI Listing
January 2020

ANTIBIOTIC RESISTANCE SURVEILLANCE OF HELICOBACTER PYLORI AT THE BIOBÍO REGION (CHILE) IN A DECADE.

Arq Gastroenterol 2019 Oct-Dec;56(4):361-366

Universidad de Concepción, Facultad de Ciencias Biológicas, Departamento de Microbiología, Concepción, Chile.

Background: Helicobacter pylori infection in Chile remains as a public and private health-care system's challenge, with a prevalence of the infection over 70%. Nowadays, antibiotic treatment of the infection is mandatory to prevent the arising of severe associated diseases but failures in the eradication therapy mainly due to clarithromycin resistance has been observed worldwide and first line eradication therapy seems to be not effective anymore in several geographical areas. Thus, health-care systems are committed to maintain an epidemiological surveillance upon the evolution of the antibiotic resistance of this priority 2 pathogen. Read More

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http://dx.doi.org/10.1590/S0004-2803.201900000-72DOI Listing
January 2020