A supramolecular look at microenvironmental regulation of limbal epithelial stem cells and the differentiation of their progeny.
Arq Bras Oftalmol 2017 Jul-Aug;80(4):268-272
Unidade de Oftalmologia, Departamento de Clínica e Cirurgia Veterinária, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal, SP, Brazil.
Various approaches have been taken to improve our knowledge of the microenvironmental regulation of limbal epithelial stem cells. Researchers have extensively investigated the roles of growth factors, survival factors, cytokines, enzymes, and permeable molecules secreted by the limbal cells. However, recent evidence suggests that stem cell fate (i. Read More