2,043 results match your criteria Arquivos Brasileiros de Oftalmologia [Journal]


Retinal dystrophies and variants in PRPH2.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):158-160

Universidade Federal de São Paulo, São Paulo, SP, Brazil.

This report presents three patients diagnosed with macular dystrophies with variants in PRPH2. Peripherin-2, the protein of this gene, is important in the morphogenesis and stabilization of the photoreceptor outer segment. Peripherin-2 deficiencies cause cellular apoptosis. Read More

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http://dx.doi.org/10.5935/0004-2749.20190033DOI Listing

Antiphospholipid syndrome and neurofibromatosis type I: a coincidence or new association?

Arq Bras Oftalmol 2019 Mar-Apr;82(2):155-157

Department of Neuro-radiology, Sheikh Khalifa Hospital, Abu Dhabi, UAE.

Numerous studies have reported on structural vascular anomalies and ischemia associated with neurofibromatosis type 1 that are thought to stem from dysfunction of neurofibromin, the neurofibromatosis type 1 protein. Documented cases of associated antiphospholipid syndrome fulfilling the accepted diagnostic criteria are exceptionally rare, with only three cases reported in the literature. Here, we report on a patient with neurofibromatosis type 1 and a history of spontaneous abortions presenting with sudden vision loss in the right eye and swelling of the optic nerve head. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190032
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http://dx.doi.org/10.5935/0004-2749.20190032DOI Listing
August 2018
9 Reads

A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):152-154

Department of Ophthalmology and Visual Sciences, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

We describe here a case of a 21-year-old woman who presented with low visual acuity, pain, and hyperemia in the left eye for 45 days. Her eye had extensive corneal infiltrate, with melting and a central perforation that was glued with cyanoacrylate, but with Seidel (+). She underwent tectonic corneal transplantation, and anterior chamber lavage with subconjunctival infiltration with voriconazole, as well as intracameral injections of amphotericin B. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190031
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http://dx.doi.org/10.5935/0004-2749.20190031DOI Listing
July 2018
2 Reads

A case of late-onset capsular block syndrome and its surgical treatment.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):149-151

Department of Ophthalmology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Capsular block syndrome is a rare complication of phacoemulsification surgery with continuous curvilinear capsulorhexis and intraocular lens implantation. Here, we report a case of very late-onset capsular block syndrome that developed 13 years after cataract extraction and present the surgical approach used for its successful treatment. Read More

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http://dx.doi.org/10.5935/0004-2749.20190030DOI Listing
March 2018
1 Read

National survey of blindness and visual impairment in Guatemala, 2015.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):91-97

Divisão de Oftalmologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

Purpose: To estimate the prevalence of blindness and visual impairment in older adults living in Guatemala.

Methods: Participants ³50 years of age were selected using random cluster sampling and evaluated using the Rapid Assessment of Avoidable Blindness method. Visual acuity was measured, and the lens was examined. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190029
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http://dx.doi.org/10.5935/0004-2749.20190029DOI Listing
October 2017
5 Reads

PICOT: Imprescriptible items in a clinical research question.

Arq Bras Oftalmol 2019 Mar-Apr;82(2)

Departamento de Oftalmologia, Otorinolaringologioa e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

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http://dx.doi.org/10.5935/0004-2749.20190028DOI Listing
September 2018

Evaluation of nutritional status in children with amblyopia.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):141-148. Epub 2019 Jan 10.

Department of Ophthalmology, Çerkezköy State Hospital, Tekirdağ, Turkey.

Purpose: We aimed to compare the body mass index and vitamin and mineral status of children with and without amblyopia.

Methods: Amblyopic children aged between 5 and 18 years (n=46) and age-matched control children (n=32) were evaluated in terms of anthropometric parameters, including height, weight, body mass index and demographic features. Serum vitamin B12 and folate were measured using an Advia Centaur XP (Siemens, Ireland) biochemistry analyzer. Read More

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http://dx.doi.org/10.5935/0004-2749.20190022DOI Listing
January 2019
1 Read

Correlation of the aqueous humor total antioxidant capacity, total oxidant status, and levels of IL-6 and VEGF with diabetic retinopathy status.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):136-140. Epub 2019 Jan 10.

Sakarya University Education and Research Hospital, Sakarya, Turkey.

Purpose: We aimed to compare the aqueous humor total oxidant status, total antioxidant capacity, and levels of interleukin-6 and vascular endothelial growth factor between patients with diabetic retinopathy and controls and to correlate these levels with the DR status.

Methods: Patients who underwent cataract surgery were enrolled. The first group (control group) comprised patients without diabetes; the second group comprised diabetic patients without retinopathy; the third group comprised patients with nonproliferative diabetic retinopathy; and the fourth group comprised patients with proliferative diabetic retinopathy. Read More

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http://dx.doi.org/10.5935/0004-2749.20190021DOI Listing
January 2019
1 Read

Effect of contact lenses on ocular biometric measurements based on swept-source optical coherence tomography.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):129-135. Epub 2019 Jan 10.

Department of Optics and Optometry and Vision Sciences. University of Valencia, Spain.

Purpose: To determine the reliability of swept- source optical coherence tomography in cases in which soft contact lenses cannot be removed when acquiring biometric measurements.

Methods: Eight subjects were included and only one eye per participant was analyzed. Each eye was measured six times by swept-source optical coherence tomography with the IOLMaster 700 instrument (Carl Zeiss Meditec, Jena, Germany). Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190020
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January 2019
2 Reads

Comparison of choroidal thickness in patients with active and stable thyroid eye disease.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):124-128. Epub 2019 Jan 10.

Ophthalmology Department, Ondokuz Mayis University, Samsun, Turkey.

Purpose: To compare the choroidal thickness in active and stable phases of thyroid eye disease.

Methods: Forty-seven eyes of 47 patients with thyroid eye disease were prospectively studied. Patients were evaluated on the basis of their clinical activity scores, with scores 33 defined as active disease. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190019
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http://dx.doi.org/10.5935/0004-2749.20190019DOI Listing
January 2019
5 Reads

Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):103-106. Epub 2019 Jan 10.

Fundación Oftalmológica Los Andes, Universidad de los Andes, Santiago, Chile.

Purpose: To report our initial experience in the treatment of Acanthamoeba keratitis with accelerated corneal collagen cross-linking.

Methods: Retrospective chart review of patients diagnosed with Acanthamoeba keratitis with progressive corneal melting who were treated with accelerated collagen cross-linking.

Results: A total of 6 eyes (5 patients) were reviewed. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190018
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http://dx.doi.org/10.5935/0004-2749.20190018DOI Listing
January 2019
2 Reads

An eye on hepatitis C: a review.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):161-167. Epub 2019 Jan 24.

Departamento de Medicina I, Universidade Federal do Maranhão, São Luís, MA, Brazil.

This review aims to caution ophthalmologists about the ocular consequences leading to the diagnosis of hepatitis C virus infection. In addition, in this context, the effects of old and new drugs are discussed in the ophthalmological setting. The importance of early diagnosis and the curative treatment of the disease has been reported in the national and international literature, demonstrating that its progression has important implications for daily clinical and surgical ophthalmological practice. Read More

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http://dx.doi.org/10.5935/0004-2749.20190027DOI Listing
January 2019
1 Read

Long-term use of topical tacrolimus ointment: a safe and effective option for the treatment of vernal keratoconjunctivitis.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):119-123. Epub 2019 Jan 24.

Department of Ophthalmology and Otolaryngology, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brazil.

Purpose: To assess the compliance, efficacy, and safety of the long-term use of topical tacrolimus for the clinical management of vernal keratoconjunctivitis.

Methods: The medical records of patients with vernal keratoconjunctivitis undergoing long-term treatment with 0.03% topical tacrolimus were retrospectively reviewed. Read More

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http://dx.doi.org/10.5935/0004-2749.20190026DOI Listing
January 2019
1 Read

Efficacy of preoperative nonsteroidal anti-inflammatory drug and the re-dilation technique in minimizing miosis after femtosecond laser in cataract surgery.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):111-118. Epub 2019 Jan 24.

Fundação Altino Ventura, Recife, PE, Brazil.

Purpose: To assess the efficacy of using a nonste-roidal anti-inflammatory drug preoperatively and of applying the re-dilation technique when necessary to minimize pupil size variation when comparing the degree of mydriasis before femtosecond laser pretreatment with that at the beginning of phacoemulsification.

Methods: This retrospective study included patients who underwent cataract surgery using the LenSx (Alcon Laboratories, Inc., Fort Worth, TX). Read More

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http://dx.doi.org/10.5935/0004-2749.20190025DOI Listing
January 2019

The Amazon Ocular Oncology Center: The first three years.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):107-110. Epub 2019 Jan 24.

Centro de Oncologia Ocular, Departamento de Ofalmologia e Ciências Visuais, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: To evaluate the first three years of The Amazon Ocular Oncology Center, the first ocular cancer center in the North of Brazil.

Methods: Here, we report patient information including patients' age, gender, diagnosis, treatment, and city of origin.

Results: Two hundred and twenty-one patients were included on this study: 160 (72%) patients came from the city of Manaus, 52 (24%) from other cities in Amazonas, and 9 (4%) from other states. Read More

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http://dx.doi.org/10.5935/0004-2749.20190024DOI Listing
January 2019
1 Read

Intermittent exotropia evaluation using the propedeutics proposed by Kushner: a 25-year study.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):98-102. Epub 2019 Jan 24.

Universidade de São Paulo, São Paulo, SP, Brazil.

Purpose: To evaluate the clinical and surgical impacts of phenomena that could occur in intermittent exotropia.

Methods: The medical records of intermittent exotropia cases from 1991 to 2014 were retrospectively reviewed. All patients underwent a series of measures, including a protocol to assess monocular occlusion based on the propedeutics proposed by Kushner. Read More

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http://dx.doi.org/10.5935/0004-2749.20190023DOI Listing
January 2019
1 Read

The effect of infra-red light on intraocular pressure.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):85-86

Department of Neurology, City General Hospital "8th September", Skopje, Republic of Macedonia.

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http://dx.doi.org/10.5935/0004-2749.20190017DOI Listing
May 2018
4 Reads

Biological modulation of corneal epithelial wound healing.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):78-84

Centro Avançado de Superfície Ocular, Departamento de Oftalmologia e Ciências Visuais, Universidade Federal de São Paulo, São Paulo, SP, Brasil.

The transparency and maintenance of corneal epithelial integrity are essential for its optical properties and, to preserve these characteristics, the epithelium undergoes continuous renewal. This renewal depends on the control of cell proliferation and differentiation mediated by mitogenic factors responsible for increasing mitoses and stimulating cellular migration. Cell-cell communication plays a pivotal role in epithelial healing process, and several cytokines and growth factors are involved in this process. Read More

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http://dx.doi.org/10.5935/0004-2749.20190016DOI Listing
February 2018
5 Reads

Optical coherence tomography angiography findings in malignant hypertensive retinopathy.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):72-77

Department of Ophthalmology, Antalya Education and Research Hospital, Antalya, Turkey.

A 33-year-old male presented to our clinic with low vision in both eyes that started during the previous week. Visual acuity was 20/63 in the right eye and 20/50 in the left eye. Fundus examination revealed signs of hypertensive retinopathy; thus, a multidisciplinary approach was adopted for the diagnosis and treatment of this patient. Read More

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http://dx.doi.org/10.5935/0004-2749.20190015DOI Listing
March 2018
4 Reads
0.440 Impact Factor

Posterior keratoconus and iris atrophy: a fortuitous association?

Arq Bras Oftalmol 2019 Jan-Feb;82(1):68-71

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

The authors describe an unusual association between posterior keratoconus and iris atrophy, confirmed by a complete ocular evaluation, scheimpflug imaging and pachymetric curve. A hypothesis for concomitant findings is discussed. Read More

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http://dx.doi.org/10.5935/0004-2749.20190014DOI Listing
October 2017
2 Reads

Trochlear-oculomotor synkinesis: another congenital cranial dysinnervation disorder?

Authors:
Ian Curi

Arq Bras Oftalmol 2019 Jan-Feb;82(1):65-67

Hospital Federal dos Servidores do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

This report documents an unusual phenomenon. A 6-year-old girl with trochlear-oculomotor synkinesis presented with superior oblique and palpebral levator co-contraction. The literature was reviewed and the possibility of classifying this entity as a congenital cranial dysinnervation disorder was speculated. Read More

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http://dx.doi.org/10.5935/0004-2749.20190013DOI Listing
March 2018
2 Reads

Bilateral clear lens extraction and intraocular lens implantation in a child with microspherophakia and Marfan syndrome.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):62-64

Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista "Julio de Mesquita Filho", Botucatu, SP, Brazil.

We report the case of a 4-year-old boy with Marfan syndrome whose parents reported he had had low visual acuity since birth. On examination, there was microspherophakia and a small subluxation of the lens. The objective refraction was -23. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190012
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http://dx.doi.org/10.5935/0004-2749.20190012DOI Listing
April 2018
6 Reads

The influence of storage method on the transparency of pig crystalline lens.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):56-61

Departament of Optics, Faculty of Physics, University of Valencia, Valencia, Spain.

Purpose: The porcine eye is frequently used as a research model. This paper analyzes the effect of different storage methods on the transparency of pig crystalline lens.

Methods: A spectral transmission curve (from 220 to 780 nm) for the crystalline lens was determined experimentally after storage in different conditions: saline solution, formalin, castor oil, and freezing at -80°C. Read More

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http://dx.doi.org/10.5935/0004-2749.20190011DOI Listing
March 2017
1 Read

Evaluating the diameter of eyedropper tips using a computer vision system.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):51-55

Department of Ophthalmology and Visual Science, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: This study aimed to determine the variation in diameters of outer and inner apertures of eyedropper tips using a computer vision system. Standardizing the size of eye drop nozzles is crucial to reduce the treatment cost of chronic eye diseases and to ensure a continued use of medication. An eyedropper volume of >20 µL (maximum storage of the conjunctival sac) causes medication wastage and increases treatment costs. Read More

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http://dx.doi.org/10.5935/0004-2749.20190010DOI Listing
January 2018
1 Read

Amniotic membrane as a biological scaffold for dental pulp stem cell transplantation in ocular surface reconstruction.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):32-37

Laboratório de Genética, Instituto Butantan, São Paulo, SP, Brasil.

Purpose: To evaluate the ability of human immature dental pulp stem cells, which are mesenchymal stem cells of neural crest origin, to differentiate into the corneal epithelium for purposes of corneal transplantation and tissue engineering when cultured on de-epithelized amniotic membranes.

Methods: We compared the immunophenotypes (ABCG2, K3/12, and vimentin) of cells grown on amniotic membranes or plastic surfaces under serum-free conditions or in culture media containing serum or serum replacement components.

Results: Immature dental pulp stem cells grown on amniotic membranes under basal conditions are able to maintain their undifferentiated state. Read More

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http://dx.doi.org/10.5935/0004-2749.20190009DOI Listing
August 2017
3 Reads

Effects of topical azithromycin, moxifloxacin, and povidone iodine on conjunctival bacterial flora in patients undergoing intravitreal injection.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):25-31

Department of Biostatistics and Medical Informatics, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.

Purpose: To compare effects of 5% topical povidone iodine with prophylactic topical azithromycin and moxifloxacin on bacterial flora in patients undergoing intravitreal injection.

Methods: A total of 132 patients were randomly assigned to receive treatment with azithromycin or moxifloxacin, or no treatment (control group). In total, 528 specimens were obtained at the time of admission, 4 days before intravitreal injection, 4 days after intravitreal injection, and 8 days after intravitreal injection. Read More

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http://dx.doi.org/10.5935/0004-2749.20190008DOI Listing
February 2018
1 Read

How to choose and conduct a research project: some advice for young investigators.

Authors:
David A Sullivan

Arq Bras Oftalmol 2019 Jan-Feb;82(1)

Schepens Eye Research Institute, Massachusetts Eye and Ear, and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.5935/0004-2749.20190006DOI Listing
November 2018
1 Read

Ocular abnormalities in morbid obesity.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):6-11

Department of Ophthalmology, Faculty of Medicine, Duzce University, Duzce, Turkey.

Purpose: Obesity is associated with eye diseases, but the underlying structural changes and pathogenic mechanisms have not been examined in detail. Here, we assessed the effects of morbid obesity on the morphometric indices of eye disease.

Methods: Morbidly obese volunteers (n=101, body mass index [BMI] ³40) and healthy individuals (n=95, BMI: 18. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190007
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http://dx.doi.org/10.5935/0004-2749.20190007DOI Listing
February 2018
6 Reads

Association between systemic activity ındex and dry eye severity in patients with primary Sjögren syndrome.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):45-50. Epub 2018 Nov 1.

Department of Rheumatology, Ankara Numune Education and Research Hospital, Turkey.

Purpose: The aim of the present study was to compare the severity of ocular and systemic findings among patients with primary Sjögren syndrome.

Methods: The study followed a prospective controlled design and comprised two groups; the test group included 58 eyes of 58 patients newly diagnosed with primary Sjögren syndrome with poor dry eye test findings and the control group included 45 right eyes of 45 healthy age- and sex-matched individuals. The ocular surface disease index score, tear osmolarity, Schirmer I test without anesthesia, fluorescein tear breakup time, and cornea-conjunctiva staining with lissamine green (van Bijsterveld scoring) were used to examine tear function in the patients via a complete ophthalmological examination. Read More

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http://dx.doi.org/10.5935/0004-2749.20190005DOI Listing
November 2018
6 Reads

Effects of ranibizumab and amfenac on the functional abilities and radiosensitivity of uveal melanoma cells.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):38-44. Epub 2018 Nov 1.

The Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Quebec, Canada.

Purpose: To evaluate the effects of ranibizumab and amfenac in human uveal melanoma cell lines and to explore the ability of these compounds to sensitize uveal melanoma cells to radiation therapy.

Methods: The 92.1 human uveal melanoma cell line was cultured and subjected to the proposed treatment (ranibizumab, amfenac, and a combination of both). Read More

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http://dx.doi.org/10.5935/0004-2749.20190004DOI Listing
November 2018
10 Reads

Effect of accelerated corneal crosslinking on ocular response analyzer waveform-derived parameters in progressive keratoconus.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):18-24. Epub 2018 Nov 1.

Ophthalmology Department, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.

Purpose: To evaluate the effect of accelerated corneal crosslinking on corneal biomechanics with an ocular response analyzer in patients with progressive keratoconus.

Methods: In this retrospective study, 50 eyes of 45 patients with progressive keratoconus who underwent accelerated corneal crosslinking were evaluated with ocular response analyzer waveform parameters before and one year after corneal crosslinking. Paired two-tailed Student's t-test was performed to compare the parameters before vs. Read More

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http://dx.doi.org/10.5935/0004-2749.20190003DOI Listing
November 2018
8 Reads

Evaluation of toxic retinopathy caused by antimalarial medications with spectral domain optical coherence tomography.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):12-17. Epub 2018 Nov 1.

Department of Medical Specialties, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Purpose: To investigate the frequency of toxic retinopathy in patients with lupus erythematosus and rheumatoid arthritis with long-term use of chloroquine diphosphate or hydroxychloroquine through spectral domain optical coherence tomography and the outcomes of ophthalmological exams (visual acuity - Snellen's table, color vision test - Ishihara's table, fundoscopy, and retinography - red-free).

Methods: A cross-sectional study was carried out involving the ophthalmologic evaluation of patients using regular chloroquine diphosphate or hydroxychloroquine for a period of 1 year or longer. The patients completed a questionnaire on their opinions and treatment regularity. Read More

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http://dx.doi.org/10.5935/0004-2749.20190002DOI Listing
November 2018
7 Reads

Correlation between pathogenic species and clinical findings, disease severity, and visual outcome in patients with fungal keratitis.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):2-5. Epub 2018 Nov 1.

Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, Universidade Estadual de São Paulo, Ribeirão Preto, SP, Brazil.

Purpose: To determine whether a correlation exists between pathogenic species and clinical findings, disease severity, and visual outcome in patients with keratitis and fungal growth in microbiological culture.

Methods: A retrospective study of patients with fungal growth in the microbiological culture of corneal scrapings. Patients were treated at an ophthalmologic reference center in Southeastern Brazil from January 1992 to October 2015. Read More

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http://dx.doi.org/10.5935/0004-2749.20190001DOI Listing
November 2018
13 Reads

On the shoulders of giants.

Authors:
Wallace Chamon

Arq Bras Oftalmol 2018 Nov-Dec;81(6):V-VII

Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

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http://dx.doi.org/10.5935/0004-2749.20180103DOI Listing
July 2018
2 Reads

Morphological and functional findings in Alström syndrome: a study of two families.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):524-528. Epub 2018 Oct 11.

Centro Brasileiro da Visão, Brasília, DF, Brazil.

Alström syndrome is a rare disorder characterized by mutations to the ALMS1 gene and clinical findings of childhood obesity, diabetes mellitus, dilated cardiomyopathy, sensorineural hearing loss, and progressive cone-rod dystrophy, which may result in blindness. Ocular manifestations occur in the first decade of life with nystagmus, blepharospasm, and photophobia leading to progressive and severe reductions in visual acuity. This study describes the retinal structure and functional aspects of four patients (8 eyes) from two different families as determined by optical coherence tomography (OCT), fundus autofluorescence, and full-field electroretinography. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180102
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http://dx.doi.org/10.5935/0004-2749.20180102DOI Listing
October 2018
5 Reads

Trichothiodystrophy: a case report of childhood glaucoma associated with non-acquired systemic disease.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):520-523. Epub 2018 Oct 11.

Pediatric Glaucoma Section, Ophthalmology Department, Universidade Federal de São Paulo/Escola Paulista de Medicina, São Paulo, SP, Brazil.

Trichothiodystrophy belongs to a group of rare genetic diseases characterized by DNA repair anomalies. Ocular manifestations can occur in 50% of cases, including cataract, refractive errors, strabismus, microcornea, microphthalmia, dry eye, and pigmentary macular changes. We report a case of childhood glaucoma in a patient with trichothiodystrophy who underwent trabeculectomy in the left eye. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180101
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http://dx.doi.org/10.5935/0004-2749.20180101DOI Listing
October 2018
4 Reads

Effect of the bioprotectant agent trehalose on corneal epithelial healing after corneal cross-linking for keratoconus.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):505-509. Epub 2018 Oct 11.

Department of Ophthalmology, Ankara Numune Education and Research Hospital, Turkey.

Purpose: This study aimed to compare the effectiveness of eye drops containing a combination of sodium hyaluronate and trehalose and sodium hyaluronate for the treatment of corneal cross-linking and epithelial healing.

Methods: This study included 46 eyes of 23 keratoconus patients who underwent corneal cross-linking on both eyes. Unpreserved trehalose 30 mg/mL and sodium hyaluronate 1. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180100
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http://dx.doi.org/10.5935/0004-2749.20180100DOI Listing
October 2018
6 Reads

Metastatic choroidal melanoma to the contralateral eye: a rare case.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):517-519. Epub 2018 Oct 11.

Intervention Radiology Service, Radiology Department, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Uveal melanoma is the most common adult primary intraocular cancer. Although liver metastasis is common to the natural history of the disease, metastasis to the fellow eye is extremely rare. Here we report the case of a 59-year-old man with choroidal melanoma in his right eye who underwent enucleation at a different center. Read More

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http://dx.doi.org/10.5935/0004-2749.20180099DOI Listing
October 2018
2 Reads

Complication of micro-bypass stenting: the anterior chamber displacement of a Xen implant.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):514-516. Epub 2018 Oct 11.

Ophthalmology Department, Bagcilar Training and Research Hospital, Istanbul Health Sciences University, Istambu, Turkey.

Although minimally invasive glaucoma surgery using different types of implants is a promising strategy for treating glaucoma, potential long-term complications require further evaluation. Here, we report a case of the anterior chamber displacement of a Xen implant due to a maneuver aimed at correcting a dysfunctional and bent subconjunctival implant. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180098
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http://dx.doi.org/10.5935/0004-2749.20180098DOI Listing
October 2018
9 Reads

The outcomes of 326 external dacryocystorhinostomy operations in children with dacryostenosis - 30-year experience of an oculoplastic surgeon.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):500-504. Epub 2018 Oct 8.

Department of Ophthalmology, World Eye Hospital, Ankara, Turkey.

Purpose: To report demographic features and surgical outcomes of 320 children undergoing external dacryocystorhinostomy for dacryostenosis.

Methods: We performed a retrospective evaluation of the records of patients aged <16 years who underwent external dacryocystorhinostomy. Patient demographic features and success rates of the operations were analyzed from the data records. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180097
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http://dx.doi.org/10.5935/0004-2749.20180097DOI Listing
October 2018
3 Reads

Trends in corneal transplantation from 2001 to 2016 in Brazil.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):529-538. Epub 2018 Oct 8.

Department of Ophthalmology, Hospital das Clínicas, Universidade de São Paulo, São Paulo, SP, Brazil.

A retrospective and analytical study was conducted by using data from the National Transplantation System on 184,575 corneal transplantations performed between January 2001 and December 2016 in order to analyze thetrends in corneal transplantation from 2001 to 2016 in Brazil. The Cochran-Armitage test, analysis of variance, and Duncan's multiple comparisons were used to verify the existence of trends, compare the mean values between regions, and verify the mean differences, respectively. A significance level of 5% was used for all tests. Read More

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http://dx.doi.org/10.5935/0004-2749.20180096DOI Listing
October 2018
2 Reads

The relationship between topical anti-glaucoma medications and the development of lacrimal drainage system obstruction.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):490-493. Epub 2018 Oct 8.

Department of Ophthalmology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Purpose: To evaluate whether any topical anti-glaucoma medications increase the risk of lacrimal drainage system obstruction or whether the presence of preservatives alone is sufficient to generate obstruction.

Methods: This nested case-control study compared a group of patients with lacrimal duct obstruction who received topical anti-glaucoma medications to a control group of patients without obstruction.

Results: The medical records of 255 patients with glaucoma who consulted the Oculoplastic Section with complaints of watery eyes were reviewed. Read More

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http://dx.doi.org/10.5935/0004-2749.20180095DOI Listing
October 2018
3 Reads

Effect of superior blepharoplasty on tear film: objective evaluation with the Keratograph 5M - a pilot study.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):471-474. Epub 2018 Oct 8.

Ophthalmology Department, Hospital de Braga, Braga, Portugal.

Purpose: To evaluate the effect of superior blepharoplasty on the tear film using the corneal topographer Keratograph 5M.

Methods: A prospective study was performed of 27 eyes of 14 patients with superior dermatochalasis who underwent superior blepharoplasty between May and June 2016. Conservative upper eyelid blepharoplasty was performed by an en bloc resection of anterior lamellar tissue that included skin, subcutaneous tissue, and the orbicularis oculi muscle. Read More

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http://dx.doi.org/10.5935/0004-2749.20180094DOI Listing
October 2018
11 Reads

Effects of combined oral doxycycline and topical cyclosporine treatment on ocular signs, symptoms, and tear film parameters in rosacea patients.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):466-470. Epub 2018 Oct 8.

Department of Ophthalmology, Adıyaman University, Turkey.

Purpose: This study reports the effects of combined use of oral doxycycline and topical cyclosporine on ocular signs, symptoms, and tear film parameters in rosacea patients.

Methods: Fifty-four right eyes of 54 patients were included in this study. All patients underwent full ophthalmologic examination-including best corrected visual acuity measurement, slit-lamp anterior segment and fundus examination, tear film break-up time, and Schirmer test-before treatment and six months post-treatment. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180093
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http://dx.doi.org/10.5935/0004-2749.20180093DOI Listing
October 2018
4 Reads

Evaluation of renin and angiotensin II levels in pseudoexfoliation syndrome.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):494-499. Epub 2018 Sep 13.

Department of Ophthalmology, Gazi University School of Medicine, Ankara, Turkey.

Purpose: Pseudoexfoliation syndrome has been linked to impaired function of the heart and blood vessels. We conducted a study to investigate the role of the renin-angiotensin system in the etiopathogenesis of pseudoexfoliation syndrome.

Methods: The subjects were 14 patients with pseudoexfoliation syndrome and 14 healthy controls who underwent cataract extraction. Read More

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http://dx.doi.org/10.5935/0004-2749.20180092DOI Listing
September 2018
2 Reads

Impact of environmental pollution on the ocular surface of Sjögren's syndrome patients.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):481-489. Epub 2018 Sep 13.

Laboratorio de Investigaciones Oculares, Buenos Aires, Argentina.

Purpose: To evaluate the effect of air pollution on the ocular surface of patients with Sjögren's syndrome.

Methods: We investigated the ocular surfaces of thirty patients with Sjögren's syndrome and thirty healthy volunteers (control group) living in the Metropolitan Area of Buenos Aires. We used nitrogen dioxide as an indicator of exposure to air pollution. Read More

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http://dx.doi.org/10.5935/0004-2749.20180091DOI Listing
September 2018
5 Reads

Ocular delivery of moxifloxacin-loaded liposomes.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):510-513. Epub 2018 Sep 13.

Department of Surgery, Universidade Federal de Pernambuco, Recife, PE, Brazil.

Purpose: To determine the release profile of moxifloxacin encapsulated in liposomes in the aqueous humor as a controlled release system for intracameral application.

Methods: Liposomes containing moxifloxacin were obtained using the lipid film hydration method and were characterized by particle size and encapsulation efficiency. Female rabbits were used for the in vivo profile release study. Read More

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http://dx.doi.org/10.5935/0004-2749.20180090DOI Listing
September 2018
2 Reads

Visual performance of scleral lenses and their impact on quality of life in patients with irregular corneas.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):475-480. Epub 2018 Sep 13.

Department of Ophthalmology, Ufuk University Faculty of Medicine, Ankara, Turkey.

Purpose: We aimed to evaluate the visual quality performance of scleral contact lenses in patients with keratoconus, pellucid marginal degeneration, and post-keratoplasty astigmatism, and their impact on quality of life.

Methods: We included 40 patients (58 eyes) with keratoconus, pellucid marginal degeneration, and post-keratoplasty astigmatism who were examined between October 2014 and June 2017 and fitted with scleral contact lenses in this study. Before fitting scleral contact lenses, we noted refraction, uncorrected distance visual acuity, spectacle-corrected distance visual acuity, uncorrected contrast sensitivity, and spectacle-corrected contrast sensitivity. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180089
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http://dx.doi.org/10.5935/0004-2749.20180089DOI Listing
September 2018
21 Reads

Evaluation of choroidal perfusion changes in obese patients: ocular effects of insulin resistance.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):461-465. Epub 2018 Sep 13.

Department of Eye Disease, Faculty of Medicine, Adiyaman University, Adıyaman, Turkey.

Purpose: We aimed to evaluate choroidal per-fusion changes in obese patients using optical coherence tomography and dynamic contour tonometry, to determine whether these changes are associated with body mass index, and to assess the ocular effects of insulin resistance.

Methods: We retrospectively evaluated the data of 32 obese patients with body mass index >30 kg/m2 and 45 healthy control individuals. Intraocular pressure and ocular pulse amplitude values of the patients were measured using dynamic contour tonometry, and the mean choroidal thickness was measured using enhanced depth imaging optical coherence tomography. Read More

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http://dx.doi.org/10.5935/0004-2749.20180088DOI Listing
September 2018
9 Reads