2,058 results match your criteria Arquivos Brasileiros De Oftalmologia[Journal]


Optic nerve involvement in ocular toxoplasmosis: 12 year data from a tertiary referral center in Turkey.

Arq Bras Oftalmol 2019 Apr 8. Epub 2019 Apr 8.

Department of Ophthalmology, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey.

Purpose: To evaluate the prevalence, clinical characteristics, and types of optic nerve involvement in patients with ocular toxoplasmosis.

Methods: For this retrospective cross-sectional study, we examined all patients with active ocular toxoplasmosis referred to our Uveitis Section during the last 12 years, and we included patients with optic nerve involvement in the study. The primary outcome was the prevalence of optic nerve involvement, and secondary outcomes included the types of optic nerve involvement and the final best-corrected visual acuity after treatment. Read More

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http://dx.doi.org/10.5935/0004-2749.20190058DOI Listing

Complications in the first 10 phacoemulsification cataract surgeries with and without prior simulator training.

Arq Bras Oftalmol 2019 Apr 8. Epub 2019 Apr 8.

Ophthalmology, Otorhinolaryngology and Head and Neck Surgery Department, Botucatu Medical School, Universidade Estadual Paulista "Julio de Mesquita Filho", Botucatu, SP, Brazil.

Purpose: To evaluate whether training medical residents with the Eyesi® cataract surgery simulator reduces the occurrence of intraoperative complications.

Methods: This was a retrospective study in which the first 10 phacoemulsification surgeries performed by two groups of second-year ophthalmology residents were evaluated, during 2014 and 2015. The first Group consisted of seven residents from 2014 who had not had previous training with the simulator. Read More

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http://dx.doi.org/10.5935/0004-2749.20190057DOI Listing

Ocular surface evaluation in pediatric Hashimoto's thyroiditis without thyroid-associated ophthalmopathy.

Arq Bras Oftalmol 2019 Apr 8. Epub 2019 Apr 8.

Department of Ophthalmology, Trabzon Kanuni Training and Research Hospital, Trabzon, Turkey.

Purpose: We aimed to assess ocular surface characteristics in children with Hashimoto's thyroiditis without thyroid-associated ophthalmopathy and compare the results with those of healthy children.

Methods: Twenty-two children with Hashimoto's thyroiditis (Group 1) and 20 healthy children without any ocular and/or systemic disorder (Group 2) were enrolled in the study. Ocular Surface Disease Index questionnaire, tear film osmolarity measurement (TearLab Osmolarity System, San Diego, CA, USA), Schirmer and tear film breakup time tests, meibography, and conjunctival brush cytology were performed and compared the results between the groups. Read More

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http://dx.doi.org/10.5935/0004-2749.20190056DOI Listing
April 2019
5 Reads

Intravitreal neurodegenerative and inflammatory mediators in proliferative diabetic retinopathy.

Arq Bras Oftalmol 2019 Apr 8. Epub 2019 Apr 8.

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Purpose: To compare the intravitreal concentrations of cellular mediators involved in neurodegeneration, inflammation, and angiogenesis in patients with proliferative diabetic retinopathy and other vitreoretinal diseases.

Methods: A multiplex bead immunoassay was used to measure vitreous levels of pigment epithelium-derived factor, serum amyloid P, C-reactive protein, complement C4, alpha-1 antitrypsin, vascular endothelial growth factor, platelet-derived growth factor-AA, platelet-derived growth factor-BB, interleukin-6, interleukin-8, interleukin-10, tumor necrosis factor alpha and beta in patients undergoing 23-gauge vitrectomy for proliferative diabetic retinopathy and other diagnoses (control group).

Results: We evaluated 55 patients, of whom 24 had proliferative diabetic retinopathy and 31 had other diagnoses including vitreous hemorrhage, retinal detachment, macular hole, and epiretinal membrane. Read More

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http://dx.doi.org/10.5935/0004-2749.20190055DOI Listing
April 2019
1 Read

Evaluation of corneal layers and anterior sclera in patients with primary Sjögren's syndrome.

Arq Bras Oftalmol 2019 Apr 8. Epub 2019 Apr 8.

Rheumatology Division, Pamukkale University, Denizli, Turkey.

Purpose: We aimed to compare the thickness of anterior sclera, corneal layers, and pre-ocular tear film between patients with primary Sjögren's syndrome and healthy individuals.

Methods: Fifty-one patients with primary Sjögren's syndrome and 41 healthy control participants were recruited in this cross-sectional and comparative study. The thickness of the pre-ocular tear film, corneal epithelium, Bowman's layer, stroma, Descemet's membrane, and endothelium were measured on the corneal apex. Read More

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http://dx.doi.org/10.5935/0004-2749.20190054DOI Listing
April 2019
2 Reads

Is it always blepharitis? Urbach-Wiethe syndrome (lipoid proteinosis).

Arq Bras Oftalmol 2019 Mar 25. Epub 2019 Mar 25.

Department of Dermatology, Istanbul Medeniyet University School of Medicine, Goztepe, Istanbul, Turkey.

A 12-year-old girl presented with recurrent crusty debris and dandruff at the base of both eyelashes despite having completed different medical treatments. She had had a hoarse voice since her early childhood. Upon anterior segment examination of the eyes, we found yellow-white, bead-like papules on the margins of the eyelids. Read More

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http://dx.doi.org/10.5935/0004-2749.20190051DOI Listing
March 2019
1 Read

Atypical presentation of fibroepithelial polyp: a report of two cases.

Arq Bras Oftalmol 2019 Mar 25. Epub 2019 Mar 25.

Department of Pathology, Faculty of Medicine, Mersin University, Mersin, Turkey.

Fibroepithelial polyps are benign non-epithelial tumors arising from mesodermal tissue and are commonly found on the skin. They can develop on the eyelid and surrounding area and rarely appear at other sites. While most cutaneous cases are diagnosed incidentally, the lesions may be symptomatic based on their location. Read More

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http://dx.doi.org/10.5935/0004-2749.20190050DOI Listing
March 2019
1 Read

Brimonidine-induced unilateral ocular lichen planus: a case report.

Arq Bras Oftalmol 2019 Mar 25. Epub 2019 Mar 25.

Servicio de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.

This report was written to describe a case of unilateral brimonidine-induced conjunctival lichen planus. Because the ophthalmic examination indicated chronic conjunctivitis or drug-induced pseudopemphigoid, the patient underwent thorough ophthalmic and systemic examinations, as well as conjunctival biopsy and direct immunofluorescence studies. A 71-year-old woman with unilateral left eye findings of chronic conjunctivitis was referred to our Ophthalmology Department. Read More

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http://dx.doi.org/10.5935/0004-2749.20190047DOI Listing

Assessing driving risk in patients with glaucoma.

Arq Bras Oftalmol 2019 Mar 25. Epub 2019 Mar 25.

Department of Ophthalmology and Visual Science, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Glaucoma is the leading cause of irreversible blindness worldwide and can affect a broad array of daily activities, including driving. Recently, studies investigating the relationship between driving performance and glaucoma have received a great deal of interest. Assessment of driving behavior is not straightforward because driving is a complex skill involving significant multi-tasking ability. Read More

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http://dx.doi.org/10.5935/0004-2749.20190046DOI Listing
March 2019
1 Read

Intravitreal and posterior subtenon triamcinolone acetonide for severe acute posterior multifocal placoid pigment epitheliopathy.

Arq Bras Oftalmol 2019 Mar 25. Epub 2019 Mar 25.

Department of Ophthalmology, McGill University Health Centre, Montreal, Quebec, Canada.

A 21-year-old man presented with visual acuity of 20/200 in both eyes. The fundus picture, fluorescein angiography, and optical coherence tomography revealed severe bilateral acute posterior multifocal placoid pigment epitheliopathy and serous macular detachments. We treated the patient with triamcinolone acetonide, an intravitreal injection (4 mg/0. Read More

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http://dx.doi.org/10.5935/0004-2749.20190045DOI Listing
March 2019
1 Read

Effectiveness of monthly and fortnightly anti-VEGF treatments for age-related macular degeneration.

Arq Bras Oftalmol 2019 Feb 25. Epub 2019 Feb 25.

Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: To study the efficacy and safety of treatments with ranibizumab and bevacizumab for exudative age-related macular degeneration.

Methods: A parallel randomized clinical trial was conducted to compare the efficacy and safety of three regimens (bevacizumab every month, bevacizumab every 2 weeks, and ranibizumab every month), followed by as-needed retreatments, for 1 year, in previously untreated individuals with age-related macular degeneration. The primary outcome was change in visual acuity and in central macular thickness after 1 year of follow-up. Read More

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http://dx.doi.org/10.5935/0004-2749.20190043DOI Listing
February 2019
2 Reads

Intraocular pressure in subjects with beta-thalassemia minor.

Arq Bras Oftalmol 2019 Feb 25. Epub 2019 Feb 25.

Department of Ophthalmology, Numune Training and Research Hospital, Adana, Turkey.

Purpose: Beta-thalassemia minor, a common hereditary blood disorder in Mediterranean countries such as Turkey, is associated with insulin resistance. Insulin resistance, in turn, can be associated with excessively high intraocular pressure and, therefore, intraocular pressure-induced blindness. This study aimed to investigate the intraocular pressure in subjects with beta-thalassemia minor. Read More

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http://dx.doi.org/10.5935/0004-2749.20190042DOI Listing
February 2019
4 Reads

Multisectorial changes in the ciliary muscle during accommodation measured with high-resolution optical coherence tomography.

Arq Bras Oftalmol 2019 Feb 25. Epub 2019 Feb 25.

Department of Optics and Optometry and Vision Sciences. University of Valencia, Valencia, Spain.

Purpose: To measure changes in the anterior ciliary muscle during accommodation at the nasal, superior, temporal, and inferior sectors by means of an anterior chamber optical coherence tomographer, and correlate them with vergence changes.

Methods: Twenty-four subjects with healthy, phakic eyes, whose mean age was 27.1 ± 8. Read More

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http://dx.doi.org/10.5935/0004-2749.20190041DOI Listing
February 2019
1 Read

Optical biometry-based axial length alterations after intravitreal dexamethasone implant.

Arq Bras Oftalmol 2019 Feb 25. Epub 2019 Feb 25.

Trakya University School of Medicine, Department of Ophthalmology, Edirne, Turkey.

Purpose: To investigate changes in axial length after intravitreal dexamethasone implantation in patients with macular edema.

Methods: We performed a prospective comparative study of 46 patients with unilateral macular edema, due to diabetic retinopathy, retinal vein occlusion, and non-infectious uveitis, who underwent dexamethasone implantation. The fellow eyes of the patients were considered the control group. Read More

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http://dx.doi.org/10.5935/0004-2749.20190040DOI Listing
February 2019
5 Reads

Objective evaluation of vision quality in pseudophakic patients with posterior capsular opacification using double-pass retinal imaging.

Arq Bras Oftalmol 2019 Feb 25. Epub 2019 Feb 25.

Waring Vision Institute, Mount Pleasant, SC, USA.

Purpose: The purpose of this study was to objectively assess the optical vision quality of patients before and after Nd:YAG capsulotomy for posterior capsular opacification using a double-pass retinal imaging system.

Methods: We retrospectively analyzed the data from 26 pseudophakic eyes with posterior capsular opacification that underwent Nd:YAG capsulotomy. The objective scatter indices, modulation transfer function cutoff frequencies, Strehl ratios, and logMAR corrected distance visual acuities were assessed before and after YAG capsulotomy with a double-pass retinal imaging system (OQAS II, Visiometrics, Spain). Read More

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http://dx.doi.org/10.5935/0004-2749.20190039DOI Listing
February 2019
1 Read

Retinal dystrophies and variants in PRPH2.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):158-160

Universidade Federal de São Paulo, São Paulo, SP, Brazil.

This report presents three patients diagnosed with macular dystrophies with variants in PRPH2. Peripherin-2, the protein of this gene, is important in the morphogenesis and stabilization of the photoreceptor outer segment. Peripherin-2 deficiencies cause cellular apoptosis. Read More

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http://dx.doi.org/10.5935/0004-2749.20190033DOI Listing

Antiphospholipid syndrome and neurofibromatosis type I: a coincidence or new association?

Arq Bras Oftalmol 2019 Mar-Apr;82(2):155-157

Department of Neuro-radiology, Sheikh Khalifa Hospital, Abu Dhabi, UAE.

Numerous studies have reported on structural vascular anomalies and ischemia associated with neurofibromatosis type 1 that are thought to stem from dysfunction of neurofibromin, the neurofibromatosis type 1 protein. Documented cases of associated antiphospholipid syndrome fulfilling the accepted diagnostic criteria are exceptionally rare, with only three cases reported in the literature. Here, we report on a patient with neurofibromatosis type 1 and a history of spontaneous abortions presenting with sudden vision loss in the right eye and swelling of the optic nerve head. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190032
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http://dx.doi.org/10.5935/0004-2749.20190032DOI Listing
August 2018
17 Reads

A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):152-154

Department of Ophthalmology and Visual Sciences, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

We describe here a case of a 21-year-old woman who presented with low visual acuity, pain, and hyperemia in the left eye for 45 days. Her eye had extensive corneal infiltrate, with melting and a central perforation that was glued with cyanoacrylate, but with Seidel (+). She underwent tectonic corneal transplantation, and anterior chamber lavage with subconjunctival infiltration with voriconazole, as well as intracameral injections of amphotericin B. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190031
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http://dx.doi.org/10.5935/0004-2749.20190031DOI Listing
July 2018
10 Reads

A case of late-onset capsular block syndrome and its surgical treatment.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):149-151

Department of Ophthalmology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Capsular block syndrome is a rare complication of phacoemulsification surgery with continuous curvilinear capsulorhexis and intraocular lens implantation. Here, we report a case of very late-onset capsular block syndrome that developed 13 years after cataract extraction and present the surgical approach used for its successful treatment. Read More

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http://dx.doi.org/10.5935/0004-2749.20190030DOI Listing
March 2018
1 Read

National survey of blindness and visual impairment in Guatemala, 2015.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):91-97

Divisão de Oftalmologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

Purpose: To estimate the prevalence of blindness and visual impairment in older adults living in Guatemala.

Methods: Participants ³50 years of age were selected using random cluster sampling and evaluated using the Rapid Assessment of Avoidable Blindness method. Visual acuity was measured, and the lens was examined. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190029
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http://dx.doi.org/10.5935/0004-2749.20190029DOI Listing
October 2017
10 Reads

PICOT: Imprescriptible items in a clinical research question.

Arq Bras Oftalmol 2019 Mar-Apr;82(2)

Departamento de Oftalmologia, Otorinolaringologioa e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

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http://dx.doi.org/10.5935/0004-2749.20190028DOI Listing
September 2018

Evaluation of nutritional status in children with amblyopia.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):141-148. Epub 2019 Jan 10.

Department of Ophthalmology, Çerkezköy State Hospital, Tekirdağ, Turkey.

Purpose: We aimed to compare the body mass index and vitamin and mineral status of children with and without amblyopia.

Methods: Amblyopic children aged between 5 and 18 years (n=46) and age-matched control children (n=32) were evaluated in terms of anthropometric parameters, including height, weight, body mass index and demographic features. Serum vitamin B12 and folate were measured using an Advia Centaur XP (Siemens, Ireland) biochemistry analyzer. Read More

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http://dx.doi.org/10.5935/0004-2749.20190022DOI Listing
January 2019
1 Read

Correlation of the aqueous humor total antioxidant capacity, total oxidant status, and levels of IL-6 and VEGF with diabetic retinopathy status.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):136-140. Epub 2019 Jan 10.

Sakarya University Education and Research Hospital, Sakarya, Turkey.

Purpose: We aimed to compare the aqueous humor total oxidant status, total antioxidant capacity, and levels of interleukin-6 and vascular endothelial growth factor between patients with diabetic retinopathy and controls and to correlate these levels with the DR status.

Methods: Patients who underwent cataract surgery were enrolled. The first group (control group) comprised patients without diabetes; the second group comprised diabetic patients without retinopathy; the third group comprised patients with nonproliferative diabetic retinopathy; and the fourth group comprised patients with proliferative diabetic retinopathy. Read More

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http://dx.doi.org/10.5935/0004-2749.20190021DOI Listing
January 2019
1 Read

Effect of contact lenses on ocular biometric measurements based on swept-source optical coherence tomography.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):129-135. Epub 2019 Jan 10.

Department of Optics and Optometry and Vision Sciences. University of Valencia, Spain.

Purpose: To determine the reliability of swept- source optical coherence tomography in cases in which soft contact lenses cannot be removed when acquiring biometric measurements.

Methods: Eight subjects were included and only one eye per participant was analyzed. Each eye was measured six times by swept-source optical coherence tomography with the IOLMaster 700 instrument (Carl Zeiss Meditec, Jena, Germany). Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190020
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http://dx.doi.org/10.5935/0004-2749.20190020DOI Listing
January 2019
12 Reads

Comparison of choroidal thickness in patients with active and stable thyroid eye disease.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):124-128. Epub 2019 Jan 10.

Ophthalmology Department, Ondokuz Mayis University, Samsun, Turkey.

Purpose: To compare the choroidal thickness in active and stable phases of thyroid eye disease.

Methods: Forty-seven eyes of 47 patients with thyroid eye disease were prospectively studied. Patients were evaluated on the basis of their clinical activity scores, with scores 33 defined as active disease. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190019
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http://dx.doi.org/10.5935/0004-2749.20190019DOI Listing
January 2019
11 Reads

Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):103-106. Epub 2019 Jan 10.

Fundación Oftalmológica Los Andes, Universidad de los Andes, Santiago, Chile.

Purpose: To report our initial experience in the treatment of Acanthamoeba keratitis with accelerated corneal collagen cross-linking.

Methods: Retrospective chart review of patients diagnosed with Acanthamoeba keratitis with progressive corneal melting who were treated with accelerated collagen cross-linking.

Results: A total of 6 eyes (5 patients) were reviewed. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190018
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http://dx.doi.org/10.5935/0004-2749.20190018DOI Listing
January 2019
9 Reads
0.440 Impact Factor

An eye on hepatitis C: a review.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):161-167. Epub 2019 Jan 24.

Departamento de Medicina I, Universidade Federal do Maranhão, São Luís, MA, Brazil.

This review aims to caution ophthalmologists about the ocular consequences leading to the diagnosis of hepatitis C virus infection. In addition, in this context, the effects of old and new drugs are discussed in the ophthalmological setting. The importance of early diagnosis and the curative treatment of the disease has been reported in the national and international literature, demonstrating that its progression has important implications for daily clinical and surgical ophthalmological practice. Read More

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http://dx.doi.org/10.5935/0004-2749.20190027DOI Listing
January 2019
1 Read

Long-term use of topical tacrolimus ointment: a safe and effective option for the treatment of vernal keratoconjunctivitis.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):119-123. Epub 2019 Jan 24.

Department of Ophthalmology and Otolaryngology, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brazil.

Purpose: To assess the compliance, efficacy, and safety of the long-term use of topical tacrolimus for the clinical management of vernal keratoconjunctivitis.

Methods: The medical records of patients with vernal keratoconjunctivitis undergoing long-term treatment with 0.03% topical tacrolimus were retrospectively reviewed. Read More

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http://dx.doi.org/10.5935/0004-2749.20190026DOI Listing
January 2019
1 Read

Efficacy of preoperative nonsteroidal anti-inflammatory drug and the re-dilation technique in minimizing miosis after femtosecond laser in cataract surgery.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):111-118. Epub 2019 Jan 24.

Fundação Altino Ventura, Recife, PE, Brazil.

Purpose: To assess the efficacy of using a nonste-roidal anti-inflammatory drug preoperatively and of applying the re-dilation technique when necessary to minimize pupil size variation when comparing the degree of mydriasis before femtosecond laser pretreatment with that at the beginning of phacoemulsification.

Methods: This retrospective study included patients who underwent cataract surgery using the LenSx (Alcon Laboratories, Inc., Fort Worth, TX). Read More

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http://dx.doi.org/10.5935/0004-2749.20190025DOI Listing
January 2019
1 Read

The Amazon Ocular Oncology Center: The first three years.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):107-110. Epub 2019 Jan 24.

Centro de Oncologia Ocular, Departamento de Ofalmologia e Ciências Visuais, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: To evaluate the first three years of The Amazon Ocular Oncology Center, the first ocular cancer center in the North of Brazil.

Methods: Here, we report patient information including patients' age, gender, diagnosis, treatment, and city of origin.

Results: Two hundred and twenty-one patients were included on this study: 160 (72%) patients came from the city of Manaus, 52 (24%) from other cities in Amazonas, and 9 (4%) from other states. Read More

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http://dx.doi.org/10.5935/0004-2749.20190024DOI Listing
January 2019
1 Read

Intermittent exotropia evaluation using the propedeutics proposed by Kushner: a 25-year study.

Arq Bras Oftalmol 2019 Mar-Apr;82(2):98-102. Epub 2019 Jan 24.

Universidade de São Paulo, São Paulo, SP, Brazil.

Purpose: To evaluate the clinical and surgical impacts of phenomena that could occur in intermittent exotropia.

Methods: The medical records of intermittent exotropia cases from 1991 to 2014 were retrospectively reviewed. All patients underwent a series of measures, including a protocol to assess monocular occlusion based on the propedeutics proposed by Kushner. Read More

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http://dx.doi.org/10.5935/0004-2749.20190023DOI Listing
January 2019
1 Read

The effect of infra-red light on intraocular pressure.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):85-86

Department of Neurology, City General Hospital "8th September", Skopje, Republic of Macedonia.

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http://dx.doi.org/10.5935/0004-2749.20190017DOI Listing
May 2018
8 Reads

Biological modulation of corneal epithelial wound healing.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):78-84

Centro Avançado de Superfície Ocular, Departamento de Oftalmologia e Ciências Visuais, Universidade Federal de São Paulo, São Paulo, SP, Brasil.

The transparency and maintenance of corneal epithelial integrity are essential for its optical properties and, to preserve these characteristics, the epithelium undergoes continuous renewal. This renewal depends on the control of cell proliferation and differentiation mediated by mitogenic factors responsible for increasing mitoses and stimulating cellular migration. Cell-cell communication plays a pivotal role in epithelial healing process, and several cytokines and growth factors are involved in this process. Read More

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http://dx.doi.org/10.5935/0004-2749.20190016DOI Listing
February 2018
9 Reads

Optical coherence tomography angiography findings in malignant hypertensive retinopathy.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):72-77

Department of Ophthalmology, Antalya Education and Research Hospital, Antalya, Turkey.

A 33-year-old male presented to our clinic with low vision in both eyes that started during the previous week. Visual acuity was 20/63 in the right eye and 20/50 in the left eye. Fundus examination revealed signs of hypertensive retinopathy; thus, a multidisciplinary approach was adopted for the diagnosis and treatment of this patient. Read More

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http://dx.doi.org/10.5935/0004-2749.20190015DOI Listing
March 2018
7 Reads
0.440 Impact Factor

Posterior keratoconus and iris atrophy: a fortuitous association?

Arq Bras Oftalmol 2019 Jan-Feb;82(1):68-71

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

The authors describe an unusual association between posterior keratoconus and iris atrophy, confirmed by a complete ocular evaluation, scheimpflug imaging and pachymetric curve. A hypothesis for concomitant findings is discussed. Read More

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http://dx.doi.org/10.5935/0004-2749.20190014DOI Listing
October 2017
3 Reads

Trochlear-oculomotor synkinesis: another congenital cranial dysinnervation disorder?

Authors:
Ian Curi

Arq Bras Oftalmol 2019 Jan-Feb;82(1):65-67

Hospital Federal dos Servidores do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

This report documents an unusual phenomenon. A 6-year-old girl with trochlear-oculomotor synkinesis presented with superior oblique and palpebral levator co-contraction. The literature was reviewed and the possibility of classifying this entity as a congenital cranial dysinnervation disorder was speculated. Read More

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http://dx.doi.org/10.5935/0004-2749.20190013DOI Listing
March 2018
3 Reads

Bilateral clear lens extraction and intraocular lens implantation in a child with microspherophakia and Marfan syndrome.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):62-64

Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista "Julio de Mesquita Filho", Botucatu, SP, Brazil.

We report the case of a 4-year-old boy with Marfan syndrome whose parents reported he had had low visual acuity since birth. On examination, there was microspherophakia and a small subluxation of the lens. The objective refraction was -23. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190012
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http://dx.doi.org/10.5935/0004-2749.20190012DOI Listing
April 2018
14 Reads

The influence of storage method on the transparency of pig crystalline lens.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):56-61

Departament of Optics, Faculty of Physics, University of Valencia, Valencia, Spain.

Purpose: The porcine eye is frequently used as a research model. This paper analyzes the effect of different storage methods on the transparency of pig crystalline lens.

Methods: A spectral transmission curve (from 220 to 780 nm) for the crystalline lens was determined experimentally after storage in different conditions: saline solution, formalin, castor oil, and freezing at -80°C. Read More

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http://dx.doi.org/10.5935/0004-2749.20190011DOI Listing
March 2017
3 Reads

Evaluating the diameter of eyedropper tips using a computer vision system.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):51-55

Department of Ophthalmology and Visual Science, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: This study aimed to determine the variation in diameters of outer and inner apertures of eyedropper tips using a computer vision system. Standardizing the size of eye drop nozzles is crucial to reduce the treatment cost of chronic eye diseases and to ensure a continued use of medication. An eyedropper volume of >20 µL (maximum storage of the conjunctival sac) causes medication wastage and increases treatment costs. Read More

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http://dx.doi.org/10.5935/0004-2749.20190010DOI Listing
January 2018
3 Reads

Amniotic membrane as a biological scaffold for dental pulp stem cell transplantation in ocular surface reconstruction.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):32-37

Laboratório de Genética, Instituto Butantan, São Paulo, SP, Brasil.

Purpose: To evaluate the ability of human immature dental pulp stem cells, which are mesenchymal stem cells of neural crest origin, to differentiate into the corneal epithelium for purposes of corneal transplantation and tissue engineering when cultured on de-epithelized amniotic membranes.

Methods: We compared the immunophenotypes (ABCG2, K3/12, and vimentin) of cells grown on amniotic membranes or plastic surfaces under serum-free conditions or in culture media containing serum or serum replacement components.

Results: Immature dental pulp stem cells grown on amniotic membranes under basal conditions are able to maintain their undifferentiated state. Read More

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http://dx.doi.org/10.5935/0004-2749.20190009DOI Listing
August 2017
4 Reads

Effects of topical azithromycin, moxifloxacin, and povidone iodine on conjunctival bacterial flora in patients undergoing intravitreal injection.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):25-31

Department of Biostatistics and Medical Informatics, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.

Purpose: To compare effects of 5% topical povidone iodine with prophylactic topical azithromycin and moxifloxacin on bacterial flora in patients undergoing intravitreal injection.

Methods: A total of 132 patients were randomly assigned to receive treatment with azithromycin or moxifloxacin, or no treatment (control group). In total, 528 specimens were obtained at the time of admission, 4 days before intravitreal injection, 4 days after intravitreal injection, and 8 days after intravitreal injection. Read More

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http://dx.doi.org/10.5935/0004-2749.20190008DOI Listing
February 2018
3 Reads

How to choose and conduct a research project: some advice for young investigators.

Authors:
David A Sullivan

Arq Bras Oftalmol 2019 Jan-Feb;82(1)

Schepens Eye Research Institute, Massachusetts Eye and Ear, and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.5935/0004-2749.20190006DOI Listing
November 2018
7 Reads

Ocular abnormalities in morbid obesity.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):6-11

Department of Ophthalmology, Faculty of Medicine, Duzce University, Duzce, Turkey.

Purpose: Obesity is associated with eye diseases, but the underlying structural changes and pathogenic mechanisms have not been examined in detail. Here, we assessed the effects of morbid obesity on the morphometric indices of eye disease.

Methods: Morbidly obese volunteers (n=101, body mass index [BMI] ³40) and healthy individuals (n=95, BMI: 18. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190007
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http://dx.doi.org/10.5935/0004-2749.20190007DOI Listing
February 2018
10 Reads

Association between systemic activity ındex and dry eye severity in patients with primary Sjögren syndrome.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):45-50. Epub 2018 Nov 1.

Department of Rheumatology, Ankara Numune Education and Research Hospital, Turkey.

Purpose: The aim of the present study was to compare the severity of ocular and systemic findings among patients with primary Sjögren syndrome.

Methods: The study followed a prospective controlled design and comprised two groups; the test group included 58 eyes of 58 patients newly diagnosed with primary Sjögren syndrome with poor dry eye test findings and the control group included 45 right eyes of 45 healthy age- and sex-matched individuals. The ocular surface disease index score, tear osmolarity, Schirmer I test without anesthesia, fluorescein tear breakup time, and cornea-conjunctiva staining with lissamine green (van Bijsterveld scoring) were used to examine tear function in the patients via a complete ophthalmological examination. Read More

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http://dx.doi.org/10.5935/0004-2749.20190005DOI Listing
November 2018
8 Reads

Effects of ranibizumab and amfenac on the functional abilities and radiosensitivity of uveal melanoma cells.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):38-44. Epub 2018 Nov 1.

The Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Quebec, Canada.

Purpose: To evaluate the effects of ranibizumab and amfenac in human uveal melanoma cell lines and to explore the ability of these compounds to sensitize uveal melanoma cells to radiation therapy.

Methods: The 92.1 human uveal melanoma cell line was cultured and subjected to the proposed treatment (ranibizumab, amfenac, and a combination of both). Read More

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http://dx.doi.org/10.5935/0004-2749.20190004DOI Listing
November 2018
12 Reads

Effect of accelerated corneal crosslinking on ocular response analyzer waveform-derived parameters in progressive keratoconus.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):18-24. Epub 2018 Nov 1.

Ophthalmology Department, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.

Purpose: To evaluate the effect of accelerated corneal crosslinking on corneal biomechanics with an ocular response analyzer in patients with progressive keratoconus.

Methods: In this retrospective study, 50 eyes of 45 patients with progressive keratoconus who underwent accelerated corneal crosslinking were evaluated with ocular response analyzer waveform parameters before and one year after corneal crosslinking. Paired two-tailed Student's t-test was performed to compare the parameters before vs. Read More

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http://dx.doi.org/10.5935/0004-2749.20190003DOI Listing
November 2018
14 Reads

Evaluation of toxic retinopathy caused by antimalarial medications with spectral domain optical coherence tomography.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):12-17. Epub 2018 Nov 1.

Department of Medical Specialties, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Purpose: To investigate the frequency of toxic retinopathy in patients with lupus erythematosus and rheumatoid arthritis with long-term use of chloroquine diphosphate or hydroxychloroquine through spectral domain optical coherence tomography and the outcomes of ophthalmological exams (visual acuity - Snellen's table, color vision test - Ishihara's table, fundoscopy, and retinography - red-free).

Methods: A cross-sectional study was carried out involving the ophthalmologic evaluation of patients using regular chloroquine diphosphate or hydroxychloroquine for a period of 1 year or longer. The patients completed a questionnaire on their opinions and treatment regularity. Read More

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http://dx.doi.org/10.5935/0004-2749.20190002DOI Listing
November 2018
8 Reads

Correlation between pathogenic species and clinical findings, disease severity, and visual outcome in patients with fungal keratitis.

Arq Bras Oftalmol 2019 Jan-Feb;82(1):2-5. Epub 2018 Nov 1.

Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, Universidade Estadual de São Paulo, Ribeirão Preto, SP, Brazil.

Purpose: To determine whether a correlation exists between pathogenic species and clinical findings, disease severity, and visual outcome in patients with keratitis and fungal growth in microbiological culture.

Methods: A retrospective study of patients with fungal growth in the microbiological culture of corneal scrapings. Patients were treated at an ophthalmologic reference center in Southeastern Brazil from January 1992 to October 2015. Read More

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http://dx.doi.org/10.5935/0004-2749.20190001DOI Listing
November 2018
20 Reads

On the shoulders of giants.

Authors:
Wallace Chamon

Arq Bras Oftalmol 2018 Nov-Dec;81(6):V-VII

Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

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http://dx.doi.org/10.5935/0004-2749.20180103DOI Listing
July 2018
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Morphological and functional findings in Alström syndrome: a study of two families.

Arq Bras Oftalmol 2018 Nov./Dec.;81(6):524-528. Epub 2018 Oct 11.

Centro Brasileiro da Visão, Brasília, DF, Brazil.

Alström syndrome is a rare disorder characterized by mutations to the ALMS1 gene and clinical findings of childhood obesity, diabetes mellitus, dilated cardiomyopathy, sensorineural hearing loss, and progressive cone-rod dystrophy, which may result in blindness. Ocular manifestations occur in the first decade of life with nystagmus, blepharospasm, and photophobia leading to progressive and severe reductions in visual acuity. This study describes the retinal structure and functional aspects of four patients (8 eyes) from two different families as determined by optical coherence tomography (OCT), fundus autofluorescence, and full-field electroretinography. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20180102
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http://dx.doi.org/10.5935/0004-2749.20180102DOI Listing
October 2018
8 Reads