534 results match your criteria Argyria


Argyria, an Unexpected Case of Skin Discoloration From Colloidal Silver Salt Ingestion.

J Emerg Med 2020 Jun 23. Epub 2020 Jun 23.

Department of Emergency Medicine, Denver Health, Denver, Colorado.

Background: Argyria is a rare condition characterized by gray/blue dislocation of the skin caused by chronic exposure to silver salts.

Case Report: We review the case of an 81-year-old man who presented to the emergency department after a motor vehicle accident, was incidentally found to have skin discoloration, and was ultimately diagnosed with argyria. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Although most emergency physicians will not complete a toxicology fellowship, all emergency physicians are on the front line of toxicological presentations and should be able to recognize argyria and differentiate this condition from other causes of skin discoloration. Read More

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http://dx.doi.org/10.1016/j.jemermed.2020.05.011DOI Listing

Effective laser treatment options for argyria: Review of literatures.

J Cosmet Dermatol 2020 Aug 3;19(8):1877-1882. Epub 2020 Jul 3.

Department of Dermatology and Cutaneous Biology Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Background: Argyria results from silver accumulation in the skin. It is a stressful condition for patients due to skin discoloration. In the past, no effective treatments were available. Read More

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http://dx.doi.org/10.1111/jocd.13549DOI Listing
August 2020
1.000 Impact Factor

Phomopsidione-Loaded Chitosan Polyethylene Glycol (PEG) Nanocomposite Dressing for Pressure Ulcers.

J Pharm Sci 2020 Jun 11. Epub 2020 Jun 11.

Universiti Kuala Lumpur, Branch Campus Malaysian Institute of Chemical and Bioengineering Technology, Lot 1988 Kawasan Perindustrian Bandar Vendor, Taboh Naning, 78000 Alor Gajah, Melaka, Malaysia.

Pressure ulcers are commonly associated with microbial infections on the wounds which require an effective wound dressing for treatment. Thus far, the available silver dressing has shown tremendous result, however, it may cause argyria and complicate the internal organ function. Hence, our study aims to develop and characterize phomopsidione-loaded chitosan-polyethylene glycol nanocomposite hydrogel (C/PEG/Ph) as an antimicrobial dressing. Read More

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http://dx.doi.org/10.1016/j.xphs.2020.06.005DOI Listing

Pulmonary toxicity of silver vapours, nanoparticles and fine dusts: A review.

Regul Toxicol Pharmacol 2020 Aug 28;115:104690. Epub 2020 May 28.

National Research Centre for the Working Environment, DK, 2100, Copenhagen, Denmark. Electronic address:

Silver is used in a wide range of products, and during their production and use, humans may be exposed through inhalation. Therefore, it is critical to know the concentration levels at which adverse effects may occur. In rodents, inhalation of silver nanoparticles has resulted in increased silver in the lungs, lymph nodes, liver, kidney, spleen, ovaries, and testes. Read More

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http://dx.doi.org/10.1016/j.yrtph.2020.104690DOI Listing

PBPK Modeling of Slightly Soluble Silver Nanomaterials and Regulatory Acceptance.

Small 2020 May 25:e1907667. Epub 2020 May 25.

Pennsylvania Bio Nano Systems, LLC, 69 Homestead Drive, Doylestown, PA, 18901, USA.

International efforts to promote predictive toxicology incorporate some form of modeling based on the regularities, insights, and hypotheses gained from analyzing laboratory studies compiled in databases. While there has been a broad commentary on definitions, metadata, and test methodologies, all necessary to establishing data repositories, there has been less on translating the resulting insights into computational models. The recent use of a computational model to support a recommended exposure limit for nanoparticulate silver is an opportunity to examine physiologically based toxicokinetics in terms of data availability, model verification and validation, and regulatory acceptance. Read More

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http://dx.doi.org/10.1002/smll.201907667DOI Listing

In vitro intestinal toxicity of commercially available spray disinfectant products advertised to contain colloidal silver.

Sci Total Environ 2020 Aug 14;728:138611. Epub 2020 Apr 14.

National Institute for Occupational Safety and Health, Morgantown, WV 26506, United States.

The use of colloidal silver-containing products as dietary supplements, immune boosters and surface disinfectants has increased in recent years which has elevated the potential for human exposure to silver nanoparticles and ions. Product mislabeling and long-term use of these products may put consumers at risk for adverse health outcomes including argyria. This study assessed several physical and chemical characteristics of five commercial products as well as their cytotoxicity using a rat intestinal epithelial cell (IEC-6) model. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.138611DOI Listing

Cellulose acetate/multi-wall carbon nanotube/Ag nanofiber composite for antibacterial applications.

Mater Sci Eng C Mater Biol Appl 2020 May 20;110:110679. Epub 2020 Jan 20.

Department of Mechanical Engineering and Robotics, Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan.

Herein we propose cellulose acetate/carbon nanotube/silver nanoparticles (CA/CNT/Ag) nanofiber composite for antibacterial applications. The nanofiber composite are expected to avoid harmful effects of silver (i.e. Read More

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http://dx.doi.org/10.1016/j.msec.2020.110679DOI Listing

Acquired Asymptomatic Blue Tongue: A Report of Exogenous Agent-associated Tongue Dyschromia and Review of Blue Tongue Etiologies.

Authors:
Philip R Cohen

Cureus 2019 Nov 27;11(11):e6243. Epub 2019 Nov 27.

Dermatology, San Diego Family Dermatology, San Diego, USA.

This study presents the case of a man who developed a temporary and asymptomatic blue tongue. The dyschromia occurred following topical contact with gelato that contained Food, Drug, and Cosmetic (FD&C) blue dye no. 1. Read More

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http://dx.doi.org/10.7759/cureus.6243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935329PMC
November 2019

Dermoscopy of localised argyria: Apropos of five cases.

Australas J Dermatol 2020 Feb 17;61(1):e122-e123. Epub 2019 Nov 17.

Department of Dermatology, Son Espases University Hospital, Palma de Mallorca, Balearic Islands, Spain.

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http://dx.doi.org/10.1111/ajd.13151DOI Listing
February 2020

Characterizations and application of CA/ZnO/AgNP composite nanofibers for sustained antibacterial properties.

Mater Sci Eng C Mater Biol Appl 2019 Dec 12;105:110077. Epub 2019 Aug 12.

Department of Mechanical Engineering and Robotics, Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan. Electronic address:

Although silver based nanofibers possess excellent bactericidal and bacteriostatic characteristics. However, excess release/contact with silver may induce harmful side-effects including carcinoma, argyria, argyrosis and allergies. Similarly, silver depletion may limit prolonged antibacterial activities as well. Read More

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http://dx.doi.org/10.1016/j.msec.2019.110077DOI Listing
December 2019
1 Read

Safety assessment of microsilver-loaded poly(methyl methacrylate) (PMMA) cement spacers in patients with prosthetic hip infections: Results of a prospective cohort study.

Bone Joint Res 2019 Aug 3;8(8):387-396. Epub 2019 Sep 3.

Hospital for Traumatology, Special Surgery and Revision Endoprosthetic Surgery, Tirschenreuth, Germany.

Objectives: Preclinical data showed poly(methyl methacrylate) (PMMA) loaded with microsilver to be effective against a variety of bacteria. The purpose of this study was to assess patient safety of PMMA spacers with microsilver in prosthetic hip infections in a prospective cohort study.

Methods: A total of 12 patients with prosthetic hip infections were included for a three-stage revision procedure. Read More

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http://dx.doi.org/10.1302/2046-3758.88.BJR-2018-0270.R1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719530PMC
August 2019
1 Read

Localized argyria from silver nasal piercing unresponsive to Q-switched laser successfully treated with a 1064 picoseconds laser.

Authors:
Firas Al-Niaimi

J Cosmet Dermatol 2020 Jun 18;19(6):1535-1536. Epub 2019 Sep 18.

Dermatological Surgery & Laser Unit, St John's Institute of Dermatology, St Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1111/jocd.13154DOI Listing
June 2020
1 Read

Electron Microscopy of Argyria Treated With Picosecond Alexandrite Laser.

Dermatol Surg 2019 Sep 10. Epub 2019 Sep 10.

Faculty of Medicine, The University of Queensland, St. Lucia, Queensland, Australia Histopathology Department, Sullivan Nicolaides Pathology, Bowen Hills, Queensland, Australia Department of Anatomical Pathology, Pathology Queensland, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia Westside Dermatology, Taringa, Queensland, Australia.

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http://dx.doi.org/10.1097/DSS.0000000000002125DOI Listing
September 2019
1 Read

Unsafe Deposits: Overlapping Cutaneous Manifestations of Porphyria Cutanea Tarda, Ochronosis, Hemochromatosis, and Argyria.

Skinmed 2019 9;17(3):161-170. Epub 2019 Sep 9.

Department of Dermatology, Rutgers University - New Jersey Medical School, Newark, NJ.

Cutaneous deposition disorders represent an array of conditions resulting from the accumulation of endogenous and exogenous substances within the skin. Many of the deposition diseases resemble each other and can also be confused with disorders not related to deposition. Porphyria cutanea tarda (PCT) results from dysfunction particularly in the fifth enzyme of the heme synthesis pathway, leading to increased skin fragility and bullae among other abnormalities. Read More

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February 2020
3 Reads

Side-by-side Comparison of a Picosecond 755-nm Alexandrite Laser and a Quality-switched 1064-nm Neodymium-doped Yttrium Aluminum Garnet Laser in the Treatment of Argyria.

Cureus 2019 Jul 23;11(7):e5206. Epub 2019 Jul 23.

Dermatology, Westside Dermatology, Seattle, USA.

Argyria is a rare but cosmetically distressing and difficult-to-treat condition for which quality-switched (Q-switched) lasers have been most commonly employed. However, at least one previous report suggests that the picosecond alexandrite laser may also serve as a successful treatment modality. Herein, we present a side-by-side comparison of a picosecond 755-nm alexandrite laser and a Q-switched 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser in the treatment of argyria. Read More

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http://dx.doi.org/10.7759/cureus.5206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692100PMC
July 2019
2 Reads

A Rare Case of Localized Argyria on the Face.

Case Rep Dermatol 2019 Jan-Apr;11(1):23-27. Epub 2019 Feb 13.

Department of Dermatology, Venerology and Allergology, Kantonsspital St. Gallen, St. Gallen, Switzerland.

Due to its antibacterial actions, silver sulfadiazine is widely used as a topical agent in the treatment of wounds, including burns. Widespread or prolonged topical application of silver sulfadiazine dressings can lead to argyria including systemic symptoms due to the resorption of silver. Here, we report a patient experiencing localized argyria due to sunlight exposure after topical use of silver sulfadiazine cream on his face. Read More

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http://dx.doi.org/10.1159/000494610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477469PMC
February 2019
11 Reads

[Bluish-gray discoloration of skin and conjunctiva].

Ophthalmologe 2020 Jan;117(1):66-68

Arbeits- und Verkehrsmedizin, Delmenhorster Str. 1, 50735, Köln, Deutschland.

Colloidal silver used as a suspension for (alternative) therapeutic purposes or silver exposure due to environmental or working conditions can lead to irreversible deposits of silver granules in the skin (bluish-gray hue of the skin), mucosa, cornea, retina and internal organs. Silver-induced discoloration of the conjunctiva should therefore be taken into account when a bluish-gray discoloration raises the suspicion of conjunctival melanoma. Read More

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http://dx.doi.org/10.1007/s00347-019-0899-xDOI Listing
January 2020
9 Reads

Cases of Argyria Associated With Colloidal Silver Use.

Ann Pharmacother 2019 08 8;53(8):867-870. Epub 2019 Apr 8.

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http://dx.doi.org/10.1177/1060028019844258DOI Listing
August 2019
10 Reads

[Silver coating on tumour prostheses].

Orthopade 2019 Jul;48(7):598-604

Univ. Klinik für Orthopädie und Traumatologie, Medizinische Universität Graz, Auenbruggerplatz 5, 8036, Graz, Österreich.

Background: Modular endoprostheses, so-called "tumour or megaprostheses" are mainly used for limb salvage surgery after resection of malignant soft tissue or a bone tumour. Sometimes, this type of prosthesis is also used for revision surgeries after failed primary joint arthroplasty. Despite continuously improving techniques and quality management systems, periprosthetic infection is one of the most serious complications. Read More

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http://dx.doi.org/10.1007/s00132-019-03720-xDOI Listing
July 2019
9 Reads

Ocular argyrosis: A case with silver deposits in cornea and lens.

Indian J Ophthalmol 2019 Feb;67(2):267-268

Department of Cornea and Refractive Surgery, Aravind Eye Hospital, Sankagiri Main Road, Nethimedu, Salem, Tamil Nadu, India.

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http://dx.doi.org/10.4103/ijo.IJO_730_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376824PMC
February 2019
32 Reads

Cellulose acetate nanofibers embedded with AgNPs anchored TiO nanoparticles for long term excellent antibacterial applications.

Carbohydr Polym 2019 Mar 12;207:640-649. Epub 2018 Dec 12.

Department of Mechanical Engineering and Robotics, Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan. Electronic address:

Silver nanoparticles (AgNPs) are effective antimicrobial agents however excess release of silver causes argyria and argyrosis. An strategy to avoid these detrimental side effects is immobilization of AgNPs on several organic and inorganic substrates. Herein, we propose immobilization of AgNPs on TiO nanoparticles by an environmentally green process subsequently incorporating the TiO/AgNP into cellulose acetate (CA) nanofiber matrix. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01448617183146
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http://dx.doi.org/10.1016/j.carbpol.2018.12.029DOI Listing
March 2019
11 Reads

Multimodal imaging in a patient with ocular argyrosis complicated by diabetic retinopathy.

Can J Ophthalmol 2018 12 24;53(6):e262-e266. Epub 2018 Apr 24.

Sunderland Eye Infirmary, Sunderland, U.K.

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http://dx.doi.org/10.1016/j.jcjo.2018.02.024DOI Listing
December 2018
12 Reads

Ochronosis Presenting as Methemoglobinemia.

J Forensic Sci 2019 May 19;64(3):913-916. Epub 2018 Sep 19.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.

Ochronosis is the blue-gray discoloration of collagen-containing tissues due to homogentisic acid (HGA) deposition, secondary to endogenous alkaptonuria or exogenous enzyme inhibition. In renal disease, accumulation of HGA in serum can cause methemoglobinemia. A 60-year-old woman with renal disease and anemia presented with 3 days of weakness and months of gray skin discoloration. Read More

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http://doi.wiley.com/10.1111/1556-4029.13907
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http://dx.doi.org/10.1111/1556-4029.13907DOI Listing
May 2019
54 Reads

Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review.

Regul Toxicol Pharmacol 2018 Oct 17;98:257-267. Epub 2018 Aug 17.

Division for Food Technology, National Food Institute, Technical University of Denmark, Søborg, Denmark. Electronic address:

Silver is used in different applications that result in contact with skin and mucosal surfaces (e.g., jewelry, wound dressings, or eye drops). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02732300183021
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http://dx.doi.org/10.1016/j.yrtph.2018.08.007DOI Listing
October 2018
12 Reads

So kann man sich versilbern.

Authors:
H Holzgreve

MMW Fortschr Med 2018 05;160(9):35

.

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http://dx.doi.org/10.1007/s15006-018-0528-7DOI Listing
May 2018
13 Reads

Silver absorption and toxicity evaluation of silver wound dressings in 40 patients with chronic wounds.

J Eur Acad Dermatol Venereol 2018 Dec 1;32(12):2295-2299. Epub 2018 Jun 1.

Department of Dermatology, Nancy University Hospital, Nancy, France.

Background: Silver-containing dressings are considered to be safe even though there have been some reports of complications, including argyria and various organ system dysfunctions. Despite the widespread use of silver dressings, little research has been done regarding the absorption and toxicity of silver.

Objective: We aimed to study the systemic absorption of silver in patients with chronic inflammatory wounds and to determine associated factors of systemic silver absorption and evaluated its association with silver toxicity. Read More

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http://dx.doi.org/10.1111/jdv.15055DOI Listing
December 2018
11 Reads

Contribution of cutlery and serving dishes to the human daily intake of silver An in vitro assessment.

Ann Biol Clin (Paris) 2018 Apr;76(2):165-172

Université Paris Diderot, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Necker-Enfants Malades, EA2373, Paris Descartes, France.

Silver cutlery and serving dishes are a potential source of exposure of humans that was never quantified. Release of silver was assessed in vitro in an acidic solution mimicking food fluid in two conditions: i] the JRC guidelines for hot fill conditions with stable high temperature over a 2 hour-period of time, and ii] a more realistic condition with spontaneous progressive decline from 90̊C to ambient temperature over the same period of time. Massive silver 95% strips were exposed to a 5% citric acid solution: i) cooling down from 90̊C to ambient or ii) 70̊C maintained, during 2 hours. Read More

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http://dx.doi.org/10.1684/abc.2018.1335DOI Listing
April 2018
8 Reads

Argyria caused by chronic ingestion of silver.

CMAJ 2018 02;190(5):E139

Department of Medicine, Sunnybrook Health Sciences Centre, Toronto Ont.

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http://www.cmaj.ca/lookup/doi/10.1503/cmaj.171374
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http://dx.doi.org/10.1503/cmaj.171374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798984PMC
February 2018
54 Reads

A case of generalized argyria presenting with muscle weakness.

Ann Occup Environ Med 2017 2;29:45. Epub 2017 Oct 2.

Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Background: Argyria is a rare irreversible cutaneous pigmentation disorder caused by prolonged exposure to silver. Herein, we report a case of generalized argyria that developed after chronic ingestion of soluble silver-nano particles and presented with muscle weakness.

Case Presentation: A 74-year-old woman visited our emergency room, complaining of fever and mental deterioration. Read More

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http://dx.doi.org/10.1186/s40557-017-0201-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625662PMC
October 2017
16 Reads

Case Report: In Vivo Confocal Microscopic Appearance of Corneal Argyrosis.

Optom Vis Sci 2017 11;94(11):1066-1069

1Department of Ophthalmology, The Eye & ENT Hospital of Fudan University, Shanghai, China 2Ophthalmology Department of Zaozhuang Municipal Hospital, Zaozhuang, Shandong, China

Significance: This report details the natural history of corneal argyrosis over 3 years using in vivo confocal microscopy to document regression of hyperreflective deposits, as well as effects on corneal nerves and endothelial cell morphology.

Purpose: To report the in vivo confocal microscopic features and clinical characteristics of a case of bilateral corneal argyrosis.

Case Report: A 52-year-old man referred to us 3 months following cautery of the palpebral conjunctiva of both eyes with a silver nitrate stick was observed over the course of 3 years, during which slit-lamp photography and in vivo confocal microscopy were performed. Read More

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http://dx.doi.org/10.1097/OPX.0000000000001133DOI Listing
November 2017
19 Reads

Localized argyria: troublesome side-effect of acupuncture.

J Eur Acad Dermatol Venereol 2018 Feb 5;32(2):e62-e65. Epub 2017 Oct 5.

Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea.

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http://dx.doi.org/10.1111/jdv.14526DOI Listing
February 2018
13 Reads

Argyrosis.

Ophthalmology 2017 09;124(9):1270

Department of Cornea and Refractive Services, Aravind Eye Care System, Madurai, India.

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http://dx.doi.org/10.1016/j.ophtha.2017.01.045DOI Listing
September 2017
17 Reads

Occupational Argyria of the Nasal Mucosa.

Head Neck Pathol 2018 Jun 4;12(2):252-254. Epub 2017 Aug 4.

Otorhyniloaryngology Unit, Civitanova Marche General Hospital, Civitanova Marche, Italy.

A biopsy specimen from the nasal mucosa of a 37-year-old man disclosed a subepithelial accumulation of black granules mainly running parallel to the surface in the absence of any inflammatory infiltrate. Since the mucosal pigment was negative with Perls' stain and resisted to melanin bleach, an exogenous pigmentation was suspected. The biopsy specimen had been taken because of a diffuse steel-blue pigmentation of the nasal mucosa, incidentally discovered during routine clinical examination. Read More

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http://dx.doi.org/10.1007/s12105-017-0842-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953866PMC
June 2018
17 Reads

Antibacterial efficacy of poly(vinyl alcohol) composite nanofibers embedded with silver-anchored silica nanoparticles.

J Biomed Mater Res B Appl Biomater 2018 04 15;106(3):1121-1128. Epub 2017 May 15.

Nano Fusion Technology Research Lab, Division of Frontier Fibers, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University 3-15-1, Tokida, Ueda, Nagono, 386-8567, Japan.

Silver has been widely used as an effective antibacterial agent especially for treating burns and wounds. However, release of silver from materials often arouse side effects due to toxicity of silver towards mammalian cells. Argyria and argyrosis are well known problems of acute toxicity of silver towards human body. Read More

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http://dx.doi.org/10.1002/jbm.b.33925DOI Listing
April 2018
44 Reads
2.760 Impact Factor

Mucocutaneous Hyperpigmentation in a Patient With a History of Both Minocycline and Silver Ingestion.

Am J Dermatopathol 2017 Dec;39(12):916-919

Department of Dermatology, Los Angeles Medical Center (LAMC), Southern California Kaiser Permanente, Los Angeles, CA.

Minocycline is a derivative of tetracycline. It has been widely used in dermatology for the treatment of acne and rosacea. One of its adverse effects is pigmentation of various body tissues. Read More

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http://Insights.ovid.com/crossref?an=00000372-201712000-0000
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http://dx.doi.org/10.1097/DAD.0000000000000920DOI Listing
December 2017
36 Reads
1.430 Impact Factor

Localized Cutaneous Argyria From a Nasal Piercing Successfully Treated With a Picosecond 755-nm Q-Switched Alexandrite Laser.

Dermatol Surg 2017 08;43(8):1094-1095

Westlake Dermatology Clinical Research Center, Westlake Dermatology & Cosmetic Surgery, Austin, Texas Division of Dermatology and Cutaneous Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas.

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http://dx.doi.org/10.1097/DSS.0000000000001162DOI Listing
August 2017
29 Reads

Ocular Argyrosis Mimicking Conjunctival Melanoma.

Cornea 2017 Jun;36(6):747-748

*Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY; †Department of Ophthalmology, Weill Cornell Medical College, New York, NY; ‡Department of Pathology, Dermatopathology Service, Memorial Sloan-Kettering Cancer Center, New York, NY; and §Pathology and Laboratory Services, Duke University Health System, Durham, NC.

Purpose: To present a novel case of ocular argyrosis mimicking conjunctival melanoma.

Methods: A 48-year-old man who is a jewelry manufacturer presented with raised pigmented lesions in the inferior fornices of both eyes. Brown-black colored, follicle-like, masses were observed in both fornices. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419866PMC
June 2017
20 Reads

Recurrence of Argyria Post Q-Switched Laser Treatment.

Dermatol Surg 2017 10;43(10):1308-1311

Department of Dermatology, University of Arizona, Tucson, Arizona Ackerman Academy of Dermatopathology, SUNY Downstate, New York, New York Pima Dermatology, Tucson, Arizona, Department of Dermatology, University of Arizona, Tucson, Arizona.

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http://dx.doi.org/10.1097/DSS.0000000000001104DOI Listing
October 2017
13 Reads

Silver-Containing Wound Cream Leading to Argyria-Always Ask About Alternative Health Products.

Am J Med 2017 Apr 31;130(4):e145-e146. Epub 2017 Jan 31.

Department of Cardiology, University of Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2016.11.036DOI Listing
April 2017
30 Reads

Silver-Containing Hydroxyapatite Coating Reduces Biofilm Formation by Methicillin-Resistant In Vitro and In Vivo.

Biomed Res Int 2016 26;2016:8070597. Epub 2016 Dec 26.

Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga 849-8501, Japan.

Biofilm-producing bacteria are the principal causes of infections associated with orthopaedic implants. We previously reported that silver-containing hydroxyapatite (Ag-HA) coatings exhibit high antibacterial activity against methicillin-resistant (MRSA). In the present study, we evaluated the effects of Ag-HA coating of implant surfaces on biofilm formation. Read More

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http://dx.doi.org/10.1155/2016/8070597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220461PMC
January 2017
24 Reads

Antimicrobial coated implants in trauma and orthopaedics-A clinical review and risk-benefit analysis.

Authors:
Volker Alt

Injury 2017 Mar 21;48(3):599-607. Epub 2016 Dec 21.

Department of Trauma, Hand and Reconstructive Surgery, University Hospital Giessen-Marburg, Campus Giessen, Rudolf-Buchheim-Str. 7, Germany. Electronic address:

Implant-associated infections remain a major issue in orthopaedics and antimicrobial functionalization of the implant surface by antibiotics or other anti-infective agents have gained interest. The goal of this article is to identify antimicrobial coatings, for which clinical data are available and to review their clinical need, safety profile, and their efficacy to reduce infection rates. PubMed database of the National Library of Medicine was searched for clinical studies on antimicrobial coated implants for internal fracture fixation devices and endoprostheses for bone surgery, for which study design, level of evidence, biocompatibility, development of resistance, and effectiveness to reduce infection rates were analyzed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00201383163081
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http://dx.doi.org/10.1016/j.injury.2016.12.011DOI Listing
March 2017
18 Reads

Dermoscopy, reflectance confocal microscopy, and high-definition optical coherence tomography in the diagnosis of generalized argyria.

J Am Acad Dermatol 2017 Feb;76(2S1):S66-S68

Department of Dermatology, University Hospital of Saint-Etienne, Saint-Etienne, France.

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http://dx.doi.org/10.1016/j.jaad.2016.07.057DOI Listing
February 2017
11 Reads

Argyria rediscovered: a close encounter with modern technology.

Authors:
S W Youn

Br J Dermatol 2016 11;175(5):870

Department of Dermatology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro, 173 Beon-gil, Seongnam, 13620, Gyeonggi-do, South Korea.

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http://dx.doi.org/10.1111/bjd.14731DOI Listing
November 2016
16 Reads

In vivo reflectance confocal microscopy characterization of silver deposits in localized cutaneous argyria.

Br J Dermatol 2016 Nov 5;175(5):1052-1055. Epub 2016 Jul 5.

Department of Dermatology, Hospital del Mar, Passeig Marítim, 25-29, ES-08003, Barcelona, Spain.

Localized cutaneous argyria is a rare condition secondary to skin deposition of silver following exposure to substances containing this metal. The clinical appearance and dermoscopy findings require deep melanocytic lesions and particularly melanoma metastasis to be ruled out. Silver deposits are usually confirmed by scanning electron microscopy and/or energy-dispersive X-ray spectroscopy. Read More

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http://dx.doi.org/10.1111/bjd.14571DOI Listing
November 2016
16 Reads

Single, blue nevus-like localized argyria.

J Dermatol 2016 Nov 20;43(11):1359-1360. Epub 2016 Apr 20.

Department of Chemical Science and Engineering, Kobe University Graduate School of Engineering, Kobe, Japan.

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http://dx.doi.org/10.1111/1346-8138.13387DOI Listing
November 2016
36 Reads

Oxidative stress and cytotoxic effects of silver ion in mouse lung macrophages J774.1 cells.

J Appl Toxicol 2017 04 14;37(4):471-478. Epub 2016 Sep 14.

Center for Health and Environmental Risk Research, National Institute for Environmental Studies, Japan.

Silver is commonly used as a disinfectant, and chronic exposure to silver may cause argyria, resulting in a gray-blue discoloration of human skin. However, the mechanism for cellular toxicity of silver has not been well explained. We studied the mode of cell death, the ratio of glutathione disulfide/glutathione, induction of metallothionein and activation of mitogen-activated protein kinases in J774. Read More

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http://dx.doi.org/10.1002/jat.3382DOI Listing
April 2017
42 Reads

Reflectance confocal microscopy and dermatopathologic findings of cutaneous argyria after colloidal silver ingestion.

J Eur Acad Dermatol Venereol 2017 Mar 16;31(3):e178-e179. Epub 2016 Aug 16.

Department of Dermatology, Medical University of Graz, Graz, Austria.

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http://doi.wiley.com/10.1111/jdv.13881
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http://dx.doi.org/10.1111/jdv.13881DOI Listing
March 2017
70 Reads

Levels of silver ions in body fluids and clinical results in silver-coated megaprostheses after tumour, trauma or failed arthroplasty.

Injury 2016 Oct 11;47 Suppl 4:S11-S16. Epub 2016 Aug 11.

Orthopaedic Oncology Unit, Careggi University-Hospital, Firenze, Italy.

Introduction: Infection in megaprostheses remains an unsolved problem, with a rate of occurrence ranging from 5% to 12%. Silver coating of medical devices has recently been proposed to reduce infection rate because of the antibacterial effect of silver. This innovation could be particularly interesting for megaprostheses, but few data have been reported in the literature. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00201383163033
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http://dx.doi.org/10.1016/j.injury.2016.07.042DOI Listing
October 2016
22 Reads

Diagnostic methods in ocular argyrosis: case report.

Doc Ophthalmol 2016 Oct 8;133(2):129-138. Epub 2016 Jul 8.

Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, ul. Ceglana 35, 40-514, Katowice, Poland.

Purpose: The aim of this report is to present a case of a patient, metal foundry worker, who had been exposed to industrial silver salts for over 20 years. It is well established that chronic exposure to silver compounds can cause accumulation of silver deposits in various tissues. This condition is referred to as argyrosis or argyria, whereas changes related to eye tissues are defined as ocular argyrosis. Read More

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http://link.springer.com/10.1007/s10633-016-9552-z
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http://dx.doi.org/10.1007/s10633-016-9552-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052328PMC
October 2016
44 Reads