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Graefes Arch Clin Exp Ophthalmol 2022 May 7. Epub 2022 May 7.

Department of Ophthalmology, LKS Faculty of Medicine, University of Hong Kong, Room 301, Block B, Cyberport 4, Hong Kong, Hong Kong.

Purpose: Peripheral anterior synechiae (PAS) have been reported as a complication after argon laser trabeculoplasty, but rarely reported after selective laser trabeculoplasty (SLT). This study aims to determine the incidence and predictors of this potential complication in phakic eyes of Chinese patients.

Methods: A retrospective review of consecutive Chinese phakic patients who underwent SLT for primary open-angle glaucoma or ocular hypertension from 2011 to 2015 was analyzed for post-operative outcomes, including the development of PAS. Read More

Case Rep Ophthalmol Med 2022 6;2022:5289203. Epub 2022 Apr 6.

Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Purpose: To introduce a new method for treating irido-corneal adhesion (ICA) by using argon laser. . A 60-year-old woman with advanced glaucoma who is undergoing trabeculectomy. Read More

Vision (Basel) 2022 Jan 21;6(1). Epub 2022 Jan 21.

Ophthalmology Unit, "Fondazione Policlinico Universitario A. Gemelli IRCCS", 00168 Rome, Italy.

Glaucoma is the most common cause of permanent blindness in the world, caused by a progressive optic neuropathy. Patients with glaucoma are often treated with topical medicines therapy in order to reduce intra-ocular pressure (IOP). On the other hand, laser therapies, with the introduction of Argon Laser Trabeculoplasty (ALT) and successively with Selective Laser Trabeculoplasty (SLT), were reported to be effective in IOP control, with low adverse effect rates. Read More

Acta Clin Croat 2021 Jun;60(2):231-236

1University of Kragujevac, Faculty of Medical Sciences, Department of Ophthalmology, Kragujevac, Serbia; 2Department of Ophthalmology, Kragujevac Clinical Center, Kragujevac, Serbia.

The aim of the study was to assess the impact of primary argon laser trabeculoplasty (ALT) on intraocular pressure (IOP) lowering and quality of life improvement in patients with pseudoexfoliative glaucoma. Sixty patients with newly diagnosed pseudoexfoliative glaucoma who underwent primary ALT (group 2) or medication therapy (group 1) were followed-up. The effect of ALT on IOP reduction, dry eye development and number of antiglaucoma drugs used was examined. Read More

Br J Ophthalmol 2021 06;105(Suppl 1):1-169

Foreword: The only time is now. Every "now" is unique. Responsible persons ask themselves, "How can I act well now?" The answers will differ for every person, because just as every situation is unique, so is every person different from every other person. Read More

Indian J Ophthalmol 2021 Oct;69(10):2741-2745

Glaucoma Fellow, Aravind Eye Hospital, Madurai, Tamil Nadu, India.

Purpose: To compare outcomes of laser assisted deep sclerectomy (LADS) and conventional trabeculectomy both combined with phacoemulsification.

Methods: We divided 36 eyes into 2 groups, one group with LADS and the other Trabeculectomy. Patients were measured post operatively at 1, 3, 6, 9 months, 1, 2, 3 years for intraocular pressure (IOP), best corrected visual acuity (BCVA) and number of medications. Read More

Clin Exp Ophthalmol 2021 12 16;49(9):1102-1110. Epub 2021 Aug 16.

Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.

Glaucoma is the second most prevalent cause of blindness worldwide, and the only effective management is the lowering of intraocular pressure (IOP). Selective laser trabeculoplasty (SLT) has become an essential part of glaucoma management since its commercial release in 2001. It has been an improvement from the previous argon laser trabeculoplasty (ALT), by using 1% of the laser energy, reducing the amount of anterior segment inflammation and minimising the degree of mechanical injury to the trabecular meshwork. Read More

Lasers Med Sci 2022 Mar 18;37(2):949-959. Epub 2021 May 18.

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.

This study compared the efficacy of modified CO laser-assisted sclerectomy surgery (CLASS) with combined CLASS and trabeculectomy (CLASS-TRAB) in patients with uveitic glaucoma (UG). UG patients who underwent CLASS-TRAB between August 2015 and April 2019 were retrospectively compared with a control group who underwent a modified CLASS standalone procedure during the same period. Visual acuity, intraocular pressure (IOP), use of supplemental medical therapy and postoperative complications were recorded at baseline, 1 week, 3 months, 6 months and 12 months. Read More

J Curr Glaucoma Pract 2020 Sep-Dec;14(3):81-86

Department of Ophthalmology, McMaster University, Hamilton, Ontario, Canada.

Aim: To describe the current practice patterns and perceptions of Canadian ophthalmologists using laser trabeculoplasty (LTP).

Materials And Methods: A cross-sectional survey of 124 members of the Canadian Ophthalmological Society (COS) who perform LTP was conducted. Descriptive statistics and Chi-square comparative analyses were performed on anonymous self-reported survey data. Read More

Eye (Lond) 2021 Jun 9;35(6):1551-1561. Epub 2021 Feb 9.

Centre for Public Health, Queen's University, Belfast, UK.

To assess the comparative effectiveness and safety of different surgical and laser techniques in people with pseudoexfoliation glaucoma (PXFG). We conducted a systematic review including randomized controlled trials (RCT) that compared any pair of surgical or laser treatment versus other type of intervention in PXFG. RCT were identified by a highly sensitive search of electronic databases and two individuals independently assessed trial eligibility, abstracted data and assessed risk of bias. Read More

Acta Ophthalmol 2021 May 29;99(3):269-274. Epub 2020 Oct 29.

Department of Clinical Sciences, Ophthalmology, Umeå University, Umeå, Sweden.

Purpose: To evaluate the intraocular pressure (IOP)-lowering effect of laser trabeculoplasty (LTP) in eyes which IOP had been substantially reduced by intensive topical treatment for one week.

Methods: Patients with newly diagnosed open-angle glaucoma were randomized to treatment with three IOP-lowering substances. One week later, 360° argon or selective LTP was performed. Read More

Am J Ophthalmol 2021 09 2;229:301-313. Epub 2020 Sep 2.

Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, People's Republic of China. Electronic address:

Purpose: We sought to comprehensively evaluate the effectiveness of different types of laser trabeculoplasty (LT) in the treatment of open-angle glaucoma.

Design: Systematic review and network meta-analysis.

Methods: Eligible randomized controlled trials were identified by searching PubMed, EMBASE, Cochrane Library, SCOPUS, China National Knowledge Infrastructure, and the Chinese Biomedical Literature Service System for studies published between January 1, 2000 and April 20, 2020. Read More

Am J Ophthalmol Case Rep 2020 Sep 29;19:100835. Epub 2020 Jul 29.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Purpose: To describe the results of selective laser trabeculoplasty (SLT) in eyes with angle recession glaucoma (ARG). To our knowledge, this is the first report of SLT being used as treatment modality for angle recession glaucoma. Argon laser trabeculoplasty (ALT) was used for ARG but showed a little therapeutic effect. Read More

J Glaucoma 2020 08;29(8):e91-e92

Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ.

Purpose: To provide the first report on argon laser peripheral iridoplasty (ALPI) to restore XEN-45 Gel stent patency after iris occlusion.

Methods: Case description, laser technique, and relevant clinical imaging.

Results: A 53-year-old African American male patient presented with progressive advanced stage primary open-angle glaucoma. Read More

Indian J Ophthalmol 2020 04;68(4):615-619

Department of Glaucoma, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.

Purpose: To determine the safety and efficacy of mitomycin C (MMC) injection versus sponge during trabeculectomy.

Methods: It is a prospective analysis of patients who underwent trabeculectomy with MMC and followed up for 1 year, divided into two groups, namely, group 1- injection (n = 21), group 2-> sponge (n = 21). The same concentration of MMC was used for both groups. Read More

Ophthalmology 2020 02;127(2):e13

West Virginia University, Morgantown, West Virginia. Electronic address:

Ophthalmology 2019 11;126(11):e83

Sri Sankaradeva Nethralaya, Guwahati, Assam, India.

Curr Opin Ophthalmol 2019 Nov;30(6):484-490

Department of Ophthalmology, Stony Brook University, Stony Brook, New York, New York, USA.

Purpose Of Review: As humans spend a considerable portion of life in the horizontal position, it is vital to better understand the effect of sleep position on glaucoma.

Recent Findings: The mean positional increase from the supine position to the lateral decubitus position (LDP) in recent literature is less than 2 mmHg for each eye in its dependent position and less than 1 mmHg in the nondependent position. The right LDP is most commonly favored sleeping position. Read More

Vestn Oftalmol 2019 ;135(4):103-107

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Laser trabeculoplasty is one of the methods used to decrease intraocular pressure (IOP) as part of comprehensive glaucoma treatment. Argon laser trabeculoplasty (ALT) and diode laser trabeculoplasty (DLT) are two of the most widely used laser trabeculoplasty techniques. The mechanism of its hypotensive action is based on the effect that laser emission photocoagulate has on trabecular meshwork and subsequent outflow facilitation, but the difference in wavelength and emission energy determine the difference in direct laser action and the features of postoperative clinical appearance. Read More

J Glaucoma 2019 09;28(9):767-771

Department of Ophthalmology, Saint Joseph Hospital.

Precis: Argon laser peripheral iridoplasty (ALPI) was performed on 48 eyes with plateau iris syndrome (PIS). Indentation gonioscopy was used to monitor the opening of the iridocorneal angle. Mean intraocular pressure (IOP) at 5 years decreased from 15. Read More

Klin Monbl Augenheilkd 2019 May 16;236(5):647-652. Epub 2019 May 16.

Augenklinik, Universitätsmedizin Mainz.

Many clinical studies have demonstrated the benefit of topical anti-inflammatory medication before and after glaucoma surgery, especially for trabeculectomy, and that they improve the long term outcome. Pre- and postoperative topical steroids improve the outcome of trabeculectomy, but duration and intensity of treatment should be adapted individually. Systemic steroid or oral immunomodulation have significant impact on the outcome in uveitic glaucoma, but not in other glaucoma subtypes. Read More

Acta Ophthalmol 2020 Feb 15;98(1):58-64. Epub 2019 May 15.

Helsinki Retina Research Group, University of Helsinki, Helsinki, Finland.

Purpose: To explore the efficacy of selective laser trabeculoplasty (SLT) within eyes with exfoliative glaucoma and history of prior argon laser trabeculoplasty (ALT).

Methods: A single-centre trial consisting of 47 patients (47 eyes) with uncontrolled exfoliative glaucoma. The main outcome measure was intraocular pressure (IOP) reduction 3 and 9 months after SLT. Read More

Eye (Lond) 2019 01 22;33(1):110-119. Epub 2018 Nov 22.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China.

Acute primary angle closure requires emergency management that involves a rapid lowering of the intraocular pressure and resolution of relative pupil block - the most common mechanism of angle closure. Emergency strategies for lowering intraocular pressure include medical treatment and argon laser peripheral iridoplasty. Anterior chamber paracentesis and diode laser transcleral cyclophotocoagulation may be considered in special situations. Read More

Ophthalmology 2019 02 29;126(2):223-232. Epub 2018 Sep 29.

Department of Ophthalmology, Western University, Ontario, Canada. Electronic address:

Purpose: The effectiveness of selective laser trabeculoplasty (SLT) was compared with argon laser trabeculoplasty (ALT) in a randomized clinical trial for patients with medically uncontrolled open-angle glaucoma who have previously received 360° SLT.

Design: An active equivalence parallel armed randomized control trial.

Participants: Patients with open-angle glaucoma including pigmentary dispersion syndrome and pseudoexfoliation syndrome were enrolled into the study from 7 different sites across Canada. Read More

Clin Ophthalmol 2018 6;12:1359-1365. Epub 2018 Aug 6.

Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Purpose: To report a 10-year review of endothelial keratoplasty (EK) procedures, Descemet's stripping automated endothelial keratoplasty (DSAEK) and Descemet's membrane endothelial keratoplasty (DMEK), and underlying diseases at a tertiary referral hospital in Japan.

Study Design: A single-center, retrospective case series.

Methods: We retrospectively reviewed all medical records of bullous keratopathy (BK) surgically treated by EK (DSAEK/DMEK) at Kanazawa University Hospital from January 2007 to December 2016. Read More

Acta Ophthalmol 2018 Aug 14;96(5):e582-e591. Epub 2018 Apr 14.

Department of Ophthalmology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.

Purpose: To report on the efficacy and safety of CO laser-assisted sclerectomy surgery (CLASS) compared with trabeculectomy in primary open-angle glaucoma and exfoliative glaucoma.

Methods: One hundred and thirty-one patients underwent CLASS (66 patients) or trabeculectomy (65 patients) and were followed up for 12 months. 'Complete success' was defined as intraocular pressure (IOP) between 10 and 18 mmHg and reduced by at least 30% from the baseline without medications, while 'qualified success' was compliant with the above criteria with or without the medications. Read More

Adv Ther 2018 05 11;35(5):619-630. Epub 2018 Apr 11.

Department of Ophthalmology, Hospital Universitario "Principe de Asturias," Universidad de Alcalá, Alcalá de Henares, Spain.

In the last decade, selective laser trabeculoplasty (SLT) has been commonly used in the management of several different types of glaucoma, as either primary or adjunct therapy. The technique has an excellent safety profile and is at least as effective as argon laser trabeculoplasty. Although the actual mechanism of action of SLT remains unclear, evidence has shown that it does not induce morphologically evident trabecular meshwork alterations. Read More

Klin Monbl Augenheilkd 2019 Oct 11;236(10):1192-1200. Epub 2018 Apr 11.

Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg.

Background: Laser trabeculoplasty (LTP) is a well established treatment modality in the management of chronic open angle glaucoma. Nonetheless there is much variation in practice.

Methods: A literature search in the PubMed database was conducted and the most important evidence-based results were summarised. Read More