6,176 results match your criteria Archivos espanoles de urologia[Journal]


Post void incontinence secondary to female urethral diverticulum.

Arch Esp Urol 2019 Jan;72(1):91-92

Hospital Universitario de Fuenlabrada. Madrid. España.

A 38 year old woman with nopast medical or surgical history of interest,derived by occasional dysuria and post voidincontinence by her family doctor, with negativeurine culture... Read More

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January 2019
1 Read

Bladder cancer with Indian ink.

Arch Esp Urol 2019 Jan;72(1):89-90

Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.

72 year old female with a historyof breast cancer in remission, under study formonosymptomatic haematuria. Cystoscopy studyshows pigmented mucosal areas.. Read More

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January 2019

[Report of two cases of malignant mesothelioma of the tunica vaginalis.]

Arch Esp Urol 2019 Jan;72(1):85-88

Servicio de Urología. Hospital General Universitario de Valencia. Valencia. España.

Objective: Paratesticular mesothelioma isan infrequent tumor and only 250 cases have been published.It originates in the scrotal tunica vaginalis. It represents0. Read More

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January 2019
1 Read

[Renal cell carcinoma metastases in rare anatomical locations: pituitary, thyroid and mammary glands. of our experience and report of three cases.]

Arch Esp Urol 2019 Jan;72(1):80-84

Servicio de Urología. Hospital de Cabuenes. Gijón. Asturias. España.

Objective: Metastatic Renal Cell Carcinoma(RCC) may develop in different anatomical locationsand after a strict follow up within normal limits. We assessthe importance of close follow up in patients with historyof RCC through 3 clinical cases with unusual locations ofmetastatic RCC.

Methods: We present 3 cases of metastatic involvementof pituitary, thyroid and mammary glands. Read More

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January 2019
1 Read

Colonizations on biofilm layers of D-J catheters under sterile urine conditions.

Arch Esp Urol 2019 Jan;72(1):75-79

Department of Urology. University of Gaziantep. Gaziantep. Turkey.

Objective: To evaluate colonizations onbiofilm layers of Double J (D-J) catheters implanted forkidney stones or ureteral stones under sterile conditions.

Methods: D-J catheters implanted between January2012 and February 2014 and removed in 0-90 days,were examined in microbiology laboratory prospectively.Fifty two patients divided into three groups regardingthe duration of the D-J catheters as; 0-30 days, 31-60days, 61-90 days. Read More

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January 2019
2 Reads

The effect of additional telerounding on postoperative outcomes, patient and surgeon satisfaction rates in the patients who underwent percutaneous nephrolithotomy.

Arch Esp Urol 2019 01;72(1):69-74

Department of Urology. Izmir Bozyaka Training and Research Hospital. Izmir. Turkey.

Introduction: We wanted to investigate the potential effect of additional telerounding system on postoperative outcomes, patient and surgeon satisfaction rates in the patients who underwent percutaneous nephrolithotomy (PNL).

Methods: Eighty patients who underwent PNL were included in the study. The patients were randomly divided to two groups. Read More

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January 2019

Results of minimally invasive procedures for ESWL refractory renal stones smaller than 2 cm: A single center experience.

Arch Esp Urol 2019 Jan;72(1):61-68

Department of Urology . Gaziantep University. Gaziantep. Turkey.

Objectives: To evaluate the efficacyand reliability of endourological procedures in patientswith renal stones up to 2 cm that were found to be resistantto extracorporeal shock wave lithotripsy (ESWL).

Methods: 611 patients who had undergone ESWLdue to renal stones up to 2 cm at the ESWL unit of ourclinic, were retrospectively evaluated. Standard percutaneousnephrolithotomy (PNL), micro-PNL, retrogradeintrarenal surgery (RIRS) was performed on the patientswho had stones resistant to ESWL. Read More

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January 2019

Retrograde intrarenal surgery or percutaneous nephrolithotomy: Which one is more effective for 1-2 cm renal stones in pediatric patients?

Arch Esp Urol 2019 Jan;72(1):54-60

Kecioren Research and Training Hospital. Department of Urology. Ankara. Turkey.

Introduction: Urinary stone diseaseis less common in pediatric age group and it has anincreasing incidence. In this study, our hypothesis is toevaluate if one of the techniques, PNL or RIRS is superiorthan the other in terms of stone free status (SFR), fluoroscopytime (FT), operation time (OT), complication rate(CR), JJ stent insertion rate, and hospitalization duration(HD) in children.

Methods: Between 2013 and 2016, 74 patients(under 18 years- old) were operated for the treatmentof renal stones between 1-2cm size. Read More

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January 2019

[Analisys of non-neurogenic lower urinary tract dysfunction patterns controlled in a Pediatric urodynamic unit.]

Arch Esp Urol 2019 Jan;72(1):45-53

Hospital Materno Infantil Teresa Herrera. A Coruña. España.

Objectives: Between 7-10% of schoolagechildren are seen by specialists for non-neurogeniclower urinary tract dysfunction (LUTD). The objective ofour study is to classify these functional alterations in difused for the diagnosis and treatment in each pattern.

Material And Methods: We reviewed patients referredto our Urodynamic Unit for suspected LUTD for3 years; We reviewed epidemiological data, supplementarytest and treatments. Read More

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January 2019
1 Read

[Clinical usefulness of the non-invasive functional study of the lower urinary tract voiding phase as a predictor of resolution after the first endoscopic treatment of vesico-ureteral reflux in children older than 3 years.]

Arch Esp Urol 2019 Jan;72(1):36-44

Sección de Urología Infantil. Servicio de Urología. Hospital Universitari i Politècnic La Fe. Valencia. España.

Objectives: To determine the usefulnessof voiding diary (VD), uroflowmetry with electromyography(UF-EMG), bladder wall thickness (before micturition)(VWTUS) and residual urine (PVR) (ultrasound measure)in predicting the outcome of the first endoscopic treatment(1ENDT) of vesicoureteral reflux (VUR) in children> 3 years.

Methods: Cross-sectional ambispective study of 48children with vesicoureteral reflux. Those with previousendoscopic treatment, age or neurological abnormalities and a history of urethralor abdominal surgery were excluded. Read More

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January 2019
1 Read

[Design and validation of a satisfaction questionnaire in patients with urolithiasis treated by extracorporeal shock wave lithotripsy (ESWL).]

Arch Esp Urol 2019 Jan;72(1):25-35

Departamento de Urología. Clínica Universidad de Navarra. Pamplona. España.

Objectives: Studying the psychosocial sphere of patients who undergo any treatment allows to have more information about its repercussion and can help the choice of an appropriate and personalized treatment. Due to the absence of specific instruments at present, the objective is to design and validate a health questionnaire regarding the treatment received with ESWL.

Methods: It was carried out in 6 phases using a sampleof 50 patients treated with ESWL in 2015 in ourcenter, whom we interviewed by telephone. Read More

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January 2019

[Primary circulating prostate cells, age and prostatic volumen predict the presence of prostate cancer in men with indication of a second prostate biopsy.]

Arch Esp Urol 2019 Jan;72(1):16-24

Servicio de Urología. Hospital de Carabineros de Chile. Santiago. Chile.

Introduction: The limitations of serumPSA as a screening test to detect prostate cancer remainproblematic, especially after an initial negative prostatebiopsy. Detection of primary circulating prostate cells(CPCs) has been reported to be useful in the detectionof prostate cancer in men with a serum PSA>4.0ng/ml. Read More

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January 2019
2 Reads

[Prostate cancer is associated with the anogenital distance, a biomarker of prenatal androgen milieu.]

Arch Esp Urol 2019 Jan;72(1):9-15

Departamento de Ciencias Sociosanitarias. Área de Medicina Preventiva y Salud Pública. Facultad de Medicina. Universidad de Murcia. Murcia. España. Grupo de Metodología de Investigación en Ciencias de la Salud. Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca). Murcia. España. CIBER Epidemiología y Salud Pública (CIBERESP). Madrid. España. Servicio de Medicina Preventiva. Hospital Clínico Universi.

Objective: To evaluate the associationbetween anogenital distance (AGD), as a biomarker ofprenatal androgen milieu, and risk of prostate cancer(PCa).

Methods: A case-control study was conducted on260 men attending a university hospital where theyunderwent physical and andrological examination andcompleted a brief questionnaire. PCa patients were confirmedby biopsy of the tumor. Read More

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January 2019

[Usefulness of photodynamic diagnosis in high-grade Bladder Cancer and subsequent BCG failure. Bibliographic review.]

Arch Esp Urol 2019 Jan;72(1):2-8

Servicio de Urología. Institut Mutualiste Montsouris. París. Francia.

Objectives: Bladder tumors are thesecond highest incidence urological tumor in the adultpopulation. In recent years, new techniques such as photodynamicdiagnosis have arisen in order to improvethe sensitivity for the detection of non muscle invasivebladder cancer (NMIBC). We intend to update the roleof photodynamic diagnosis in the diagnosis of NMIBC,in cases refractory to BCG and as a treatment in therecurrent bladder cancer. Read More

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January 2019

[Antibiotic prophylaxis for flexible cystoscopy. Perspectives for Latin America and Caribbean.]

Arch Esp Urol 2019 Jan;72(1)

Clínica de Urología Avanzada UROZEN Lima. Lima. Perú.

Sr. Editor: Los resultados de Cano-García et al. (1) en el último estudio publicado sobre la profilaxis antibiótica con ciprofloxacino en uretrocistoscopia flexible (UF) son claros y fuertes, si bien la pregunta clínica pudo ser respondida mediante un estudio de intervención (ensayo clínico), el diseño utilizado es bueno y aproximado pero difiriendo de algunos puntos claves: aleatorización, denominación de grupo control y asignación del tratamiento. Read More

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January 2019

Vitamin D deficiency in infertile patients.

Arch Esp Urol 2018 Dec;71(10):850-855

Department of Urology. Ataturk University Medical Faculty. Erzurum. Turkey.

Objectives: According to the WorldHealth Organization (WHO) definition, infertility is "thefailure of a sexually active, non-contracepting couple toachieve pregnancy in one year" and is a complicateddisorder with its medical, psychosocial and economicaspects. There is some proof that vitamin D deficiencyhas important effects on the male reproductive system.There are numerous animal trials and a limited numberof human trials investigating this topic. Read More

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December 2018
6 Reads

Skin metastasis of prostate cancer. An unusual entity.

Arch Esp Urol 2018 Dec;71(10):869-870

Servicio de Urología. Complejo Asistencial de Salamanca. Salamanca. España.

Male, 64 year old male, whoconsults to the Dermatology office presentingtwo-month, progressive, skin lesions in thepubic region... Read More

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December 2018
1 Read

Three pelvic fused kidneys.

Arch Esp Urol 2018 Dec;71(10):867-868

UGC Urología. Hospital La Inmaculada. Huercal-Overa. Almeria. España.

Pelvic renal ectopia is a rare anatomical abnormality that can present in different forms andlocations (1)... Read More

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December 2018
1 Read

Urinary bladder xanthoma: Two case reports and a review of the literature.

Arch Esp Urol 2018 Dec;71(10):862-866

Department of Pathology. Policlinico San Martino Hospital. University of Genova. Genova. Italy.

Objective: We present two rare cases ofbladder xanthomata associated with transitional cell carcinoma.

Method And Results: Cases description and selectionof related pictures. Review of the existing literature. Read More

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December 2018
1 Read

Eosinophilic cystitis treated with hydrodistention and complementary methods: Case report.

Arch Esp Urol 2018 Dec;71(10):859-862

Clinica de Urología Avanzada UROZEN. Lima. Perú.

Objective: Even though there is no established standard therapy for Eosinophilic cystitis (EC), the series of cases guide us in the treatment of patients. We report our therapeutic experience with hydrodistention and complementary methods. In order to establish a standard treatment in patients with EC. Read More

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December 2018
7 Reads

[Intense urethrorrhagia after retropubic radical prostatectomy with selective embolization of the internal pudendal artery.]

Arch Esp Urol 2018 Dec;71(10):856-859

Servicio de Urología. Hospital General Universitario Gregorio Marañón. Madrid. España.

Objective: Urethrorrhagia after radicalprostatectomy(RP) is very uncommon, regardless of the surgicalapproach used. Arterio-urethral fistula formation betweeninternal pudendal artery branches(IPA) and bulbarurethra is an exceptional finding.

Methods: We report what we consider the first series oftwo cases (one has already been published) of urethrorrhagiaafter open retropubic RP due to urethrovascular fistulaformation with its origin in the IPA or in one of its terminalbranches. Read More

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December 2018
1 Read

[Testicular Microlithiasis: Update on diagnosis and management.]

Arch Esp Urol 2018 Dec;71(10):840-849

Laboratorio de Andrología, Microbióloga y Química Clínica. Instituto Nacional de Perinatología. Isidro Espinosa de los Reyes. Ciudad de México. México.

Testicular microlithiasis (TM) is an uncommonurologic condition incidentally diagnosed byscrotal ultrasound. It has been associated with differentdiseases, such as Klinefelter`s syndrome, testicular atrophy,cryptorchidism, testicular torsion, and infertility.However, it can also present in healthy males that haveno associated risk factors. Read More

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December 2018
3 Reads

[Cost effectiveness of Mirabegron and antimuscarinic drugs in patients with hiperactive bladder.]

Arch Esp Urol 2018 Dec;71(10):809-824

Astellas Pharma Europe Ltd. Chertsey. Reino Unido.

Objective: To evaluate the costeffectivenessof mirabegron in comparison to theantimuscarinic drugs tolterodine, solifenacin andfesoterodine, in the treatment of urgency, increasedmicturition frequency and urinary incontinence in patientswith overactive bladder (OAB).

Material And Methods: A Markov model in Excel,with a time horizon of 5 years was developed fromthe National Health System and societal perspective.Clinical effectiveness was estimated from a clinical trial(SCORPIO) and a network meta-analysis. Read More

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December 2018
1 Read

[First prostate biopsy vs rebiopsy: Analysis of our series.]

Arch Esp Urol 2018 Dec;71(10):825-831

Servicio de Urología. Hospital Reina Sofía de Tudela. Navarra. España.

Introduction: Prostate re-biopsydoes not guarantee detection of prostate cancer(PC), sometimes leading to overdiagnosis of clinicallyinsignificant tumors. The present study shows theincidence of PC in our hospital and analyzes thedistribution of risk groups and prognosis depending inthe diagnosis obtained by first biopsy vs rebiopsy.

Objectives: 1. Read More

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December 2018
1 Read

[Tissue arrays: Two simple and economical methods for manual construction.]

Arch Esp Urol 2018 Dec;71(10):832-839

Servicio de Urología. Complexo Hospitalario Universitario de Vigo. Pontevedra. España.

Objectives: Tissue array (TA) technologyis widely used as a method for the in situ investigation oftissue markers in cancer studies. A limitation of this techniqueis the high price of tissue arrayers. We describetwo easy and non-expensive manual methods, that haveproduced small and medium format arrays. Read More

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December 2018
1 Read

[Urinoma secondary to ureteral fistula.]

Arch Esp Urol 2018 Nov;71(9):806-807

Hospital Reina Sofía de Tudela. Navarra. España.

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November 2018
12 Reads

[Inguinoscrotal hematoma after radical orchiectomy.]

Arch Esp Urol 2018 Nov;71(9):805

Hospital Universitario de Fuenlabrada. Madrid. España.

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November 2018
1 Read

[Hyponatremia as a presenting sign of metastatic disease in muscle invasive bladder cancer.]

Arch Esp Urol 2018 Nov;71(9):799-804

Servicio de Urología. Hospital Universitario Marqués de Valdecilla. Santander. España.

Objective: Bladder cancer is a commonly diagnosed malignancy in Europe, being 30% muscle-invasive at diagnosis. In these patients, metastases can develop both at diagnosis and after progression. Metastatic disease can manifest in a number of different ways, even as hydroelectrolytic alterations. Read More

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November 2018
11 Reads

[Nested variant Transitional Cell Carcinoma. Report of two cases and bibliographic review.]

Arch Esp Urol 2018 Nov;71(9):794-799

HUV Macarena. Sevilla. España.

Objective: Nested type transitional cell carcinoma of the bladder is a rare histological variant among bladder tumors. Although clinical presentation is similar to the other bladder tumors, its macroscopic appearance may be equivocally benign, with submucosal growing which is difficult to detect on cystoscopy, so that diagnosis may be delayed.

Methods: We present the characteristics of nested type transitional cell carcinoma and review the differential diagnosis for this entity with possible counterfeiters. Read More

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November 2018
9 Reads

Drug resistance restricts the efficacy of short term low dose Mitomycin-C treatment in UMUC-3 bladder cancer cells.

Arch Esp Urol 2018 Nov;71(9):783-793

Department of Urology. Selcuk University Faculty of Medicine. Konya. Turkey.

Objective: Mitomycin-c (MMC) is the most used intravesical adjuvant agent in non-muscle invasive bladder cancer to prevent recurrence. However, a consensus on about appropriate dosage and treatment schedule of MMC is lacking. We, therefore, aimed to evaluate the most appropriate MMC dosage using an in vitro model of high-grade human bladder cancer. Read More

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November 2018
8 Reads

Does the use of fluoroscopy really affect the success rate of retrograde intrarenal surgery?

Arch Esp Urol 2018 Nov;71(9):772-781

Department of Urology. Kecioren Research and Training Hospital. Ankara. Turkey.

Introduction: Fluoroscopy is used for access sheath insertion and postoperative control during retrograde intrarenal surgery (RIRS) operation but with this technique both patient and operation team are exposed to radiation. The use of fluoroscopy is disadvantage for both patient and surgeon. Considering results of recent studies, it is clearly seen that fluoroscopy doesn't affect the success and complication rates of RIRS. Read More

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November 2018
1 Read

[Therapeutic compliance in patients with renal lithiasis and biochemical risk factors.]

Arch Esp Urol 2018 Nov;71(9):765-771

Servicio de Urología. Hospital Universitario Virgen del Rocío. Sevilla. España.

Objective: To evaluate patient compliance with treatment for urinary lithiasis and to detect differences in adherence, causes of this behavior and associated factors.

Methods: We performed a retrospective study of 93 patients with positive urinary metabolic study (UMS) for lithogenic pathology, diagnosed between 2013 and 2015, gathering data from the digital medical records and a structured telephonic questionnaire in 75 of them. Results were analyzed using the X2 test. Read More

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November 2018
10 Reads

[Renal cell carcinoma in von Hippel-Lindau disease. Nephron sparing surgery.]

Arch Esp Urol 2018 Nov;71(9):757-764

Hospital Universitario Cruces. Baracaldo. Bizkaia. España.

Objectives: We reviewed the feasibility and safety of nephron sparing surgery for renal cell carcinoma in patients with von Hippel Lindau (VHL) disease.

Methods: We selected 22 patients with (VHL) disease with a mean age of 43 (range 30-56), from whom 16 underwent radical nephrectomy or nephron sparing surgery at our department between 2000 and 2015.

Results: A total of 33 tumors were treated, by either tumorectomy (n=20), partial nephrectomy (n=5), percutaneous renal radiofrequency ablation (n=3) edaor radical nephrectomy (n=5). Read More

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November 2018
12 Reads

[Is there a correlation between abdominal leak pressure point, incontinence severity and quality of life in patients with stress urinary incontinence?]

Arch Esp Urol 2018 Nov;71(9):752-756

Centro Urológico Profesor Bengió Córdoba. Córdoba. Argentina.

Objectives: To evaluate if there is a correlation between the abdominal leak pressure point (ALPP) of the urodynamic study and several tools to evaluate severity and quality of life associated to stress urine incontinence (SUI).

Methods: Prospective correlation study of women referred to urodynamic study for stress urinary incontinence in Centro Urológico Profesor Bengió between September 2014 and October 2015. Anamnesis, physical examination (where the SUI was demonstrated), ICIQSF urine incontinence questionnaire and incontinence impact questionnaire (IIQ-7) were performed to every patient. Read More

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November 2018
2 Reads

[Urinary lithiasis, a disease followed through its historical footprints.]

Arch Esp Urol 2018 Nov;71(9):750-751

Madrid. España.

Objetive: Through two historic episodes we find that they are closely related with urinary lithiasis.

Methods: The cases are described and documented in the same historical account.

Results: The lithiasic disease of two historical known characters. Read More

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November 2018
1 Read

[A child's memory.]

Arch Esp Urol 2018 Nov;71(9):743-749

Madrid. España.

Objectives: It is exceptional that the data of a disease are taken from a historical account in which the author, King Alfonso X the Wise himself, in one of the songs (Cantigas) to Mary, the Virgin (monument of universal literature), recites the facts from his childhood in the city of Cuenca, in the middle of August of 1226. These Facts had a great resonance.

Methods: The medical studies were in full decay that did not improve until the creation of the Universities (Paris, Naples, Padua, Bologna and Montpellier). Read More

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November 2018
2 Reads

[Recommendations for follow up in castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):735-742

UGC de Urología. Hospital Universitario Virgen de las Nieves. Granada. España.

Objectives: There is no broad consensus about what diagnostic tests use for CRPC follow up as well as their frequency. Our objective is to review and analyze the most important CRPC follow up patterns described in the literature to date.

Methods: We performed a critical analysis of the recommendations for follow up most universally employed (PCWG3, RADAR, St Gallen consensus, NCCN guidelines, EAU guidelines) RESULTS: CT scan and bone scan are the routine recommended diagnostic tests, in front of other techniques such as PET/CT or MRI, that may improve the diagnostic efficacy but they have the problem of availability and lack of internal validity for follow up. Read More

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September 2018
17 Reads

[Aggressive variants of castration resistant prostate cancer (CRPC): neuroendocrine prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):721-734

Servicio de Urología. Hospital Universitario Fundación Jiménez Díaz (HUFJD)y Hospitales Públicos Grupo QuirónSalud Madrid. Universidad Autónoma de Madrid (UAM). Madrid. España.

Castration resistant prostate cancer (CRPC) is characterized by an important molecular, pathological and clinical heterogeneity. Although most of them present androgen receptor (AR) signal dependence, there are independent phenotypes. Neuroendocrine prostate cancer (NEPC) is a rare histologic subtype with adverse prognosis due to late diagnosis, heterogeneous clinical features and lack of effective systemic treatments. Read More

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September 2018
16 Reads

[Sequencing and combination of agents in castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):711-720

Servicio de Urología. Hospital Universitario Puerta del Mar. Cádiz. España.

Prostate Cancer is the second most frequent malignant neoplasm in males in the world. At the end of the disease, when the tumor becomes resistant to castration, we have a wide range of treatment possibilities aimed at the Androgenic Receptor, androgens synthesis, the skeleton, chemotherapy, and even new molecular targets that are still under investigation. Today, the best sequence of treatment for each patient has not been established yet. Read More

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September 2018
12 Reads

[Prognostic factors and response predictors in castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):704-710

Departamento de Urología. Clínica Universidad de Navarra. Pamplona. España.

Prostate cancer is a health problem in many Countries worldwide. Understanding the essential function of androgens in the prostate physiology led to the development of hormonal blockade as a therapeutic option in advanced disease, with limited response with time and development of resistance. In this stage, where castration resistant prostate cancer (CRPC) is defined, it is associated with poor prognosis because survival varies between 18 and 24 months. Read More

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September 2018
9 Reads

[Radium 223 in castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):696-703

Hospital Universitario Basurto. Bilbao. España.CIBERONC.España.

Objective: To analyze the available evidence on Radium 223 therapy, an alfa particle emitter with specific action on bone metastases, studied on patients with castration resistant prostate cancer.

Evidence Acquisition: We review the pivotal study ALSYMPCA, that served to get the drug approval for this phase of the disease, and the new data obtained from its use. We also performed a search of ongoing studies with Radium 223 alone or in combination with other molecules. Read More

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September 2018
12 Reads

[Immunotherapy in castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):685-695

Departamento de Urología. Clínica Universidad de Navarra. Madrid/Pamplona. España.

We review the role of immunotherapy in castration resistant prostate cancer. Two immunotherapeutic strategies have been applied, isolated or in combination, either with each other or with other agents with demonstrated efficacy in this scenario that would play a role as immunomodulators: vaccines or monoclonal antibodies aimed to block immune response checkpoint inhibitors. Although CRPC presents, a priori, characteristics suggesting that immunotherapy may play a relevant role as a therapeutic strategy, its clinical application has demonstrated a limited and heterogeneous activity, in terms of proportion of responders and response intensity. Read More

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September 2018
9 Reads

[Chemotherapy in metastatic castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):676-684

Servicio de Hematología y Oncología Médica. Hospital General Universitario Morales Meseguer. Murcia. España. Universidad Católica San Antonio de Murcia (UCAM). Murcia. España.

Prostate cancer is the second mortality cause among males with cancer. Patients with metastatic castration resistant prostate cancer (mCRPC) essentially die due to tumor progression in a castration resistance situation. Docetaxel based chemotherapy was the first therapeutic strategy that demonstrated a survival increase, in addition to pain decrease, increase in tumor responses and quality of life benefit, and it currently continues being useful after the incorporation of new therapies for the treatment of mCRPC. Read More

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September 2018
1 Read

[Enzalutamide in castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):664-675

Servicio de Urología. Hospital Universitario La Paz. Madrid. España.

Androgen deprivation therapy is part of the initial treatment of patients with metastatic prostate cancer. Nevertheless, after an initial response and despite maintaining an effective testosterone suppression, the tumor is able to continue growing.Enzalutamide is an oral second generation pure antiandrogen that acts at various levels in the signal activation cascade of the androgen receptor and has demonstrated being effective in this phase of the disease. Read More

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September 2018
3 Reads

[Abiraterone in castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):651-663

Servicio de Urología. Hospital Universitario de Jerez de la Frontera. Cádiz. España.

Objectives: Prostate cancer is the most frequent neoplasia diagnosed in males. Treatment of metastatic prostate cancer is based on androgen deprivation therapy (ADT) up to its change to the castration resistance state. Recently, new molecules have been developed that significantly increase survival and quality of life of these patients. Read More

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September 2018
15 Reads

[Molecular biology of castration resistant prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):639-650

Servicio de Oncología Medica. Hospital Universitario Marques de Valdecilla. Santander. Cantabria. España.

Objectives: Castration resistant prostate cancer (CRPC) is an heterogeneous disease the molecular basis of which we are starting to know in depth. Currently, there are various pathways and targets under study, and probably many others to be characterized. In this paper, we review the most recent knowledge concerning the molecular biology of CRPC with a special focus on the therapeutic application of this knowledge. Read More

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September 2018
3 Reads

[Castration resistance mechanisms in prostate cancer.]

Arch Esp Urol 2018 Sep;71(8):628-638

Servicio de Urología. Hospital Universitario A Coruña. A Coruña. España.

The androgen-signaling axis plays a pivotal role in the pathogenesis of prostate cancer. Since the landmark discovery by Huggins and Hodges, gonadal depletion of androgens has remained a mainstay of therapy for advanced disease. However, invariably progression to castration-resistant prostate cancer (CRPC) occurs within 2-3 years of initiation of ADT. Read More

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September 2018
21 Reads

[Metastatic castration resistant prostate cancer: 2018 perspective.]

Authors:
B Miñana López

Arch Esp Urol 2018 Sep;71(8):625-627

Departamento de Urología. Clínica Universidad de Navarra. Madrid. España.

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September 2018
1 Read

Sports renal injury: Emergency nephrectomy.

Arch Esp Urol 2018 09;71(7):622-623

Hospital Nuestra Senyora de Meritxell Escaldes Engordany. Andorra.

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September 2018
3 Reads

Large size stone impacted in urethral meatus.

Arch Esp Urol 2018 09;71(7):621

Gerencia de Atención Integrada de Albacete. Albacete. España.

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September 2018
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