1,643 results match your criteria Archives of medical science : AMS[Journal]


Vitamin D serum levels in women using contraception containing drospirenone - a preliminary study.

Arch Med Sci 2019 Mar 20;15(2):554-557. Epub 2017 Oct 20.

First Department of Obstetrics and Gynecology, Centre of Postgraduate Medical Education, Warsaw, Poland.

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https://www.termedia.pl/doi/10.5114/aoms.2017.70887
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http://dx.doi.org/10.5114/aoms.2017.70887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425194PMC
March 2019
5 Reads

New antihistamines - perspectives in the treatment of some allergic and inflammatory disorders.

Arch Med Sci 2019 Mar 4;15(2):537-553. Epub 2018 Feb 4.

Department of Pharmacodynamics, Centre for Preclinical Research and Technology, Medical University of Warsaw, Warsaw, Poland.

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https://www.termedia.pl/doi/10.5114/aoms.2017.68534
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http://dx.doi.org/10.5114/aoms.2017.68534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425212PMC
March 2019
3 Reads

Lack of association of -863C/A (rs1800630) polymorphism of tumor necrosis factor-a gene with rheumatoid arthritis.

Arch Med Sci 2019 Mar 5;15(2):531-536. Epub 2018 Jul 5.

Arthritis Research Center, Rahmat Noor Clinic, Rawalpindi, Pakistan.

Introduction: Multifunctional pro-inflammatory cytokine tumor necrosis factor-α (TNF-α) has been implicated in a variety of inflammatory diseases including rheumatoid arthritis (RA). TNF-α polymorphisms are mostly located in its promoter region and play a significant role in disease susceptibility and severity. We therefore sought to investigate TNFA -863C/A (rs1800630) polymorphism association with RA activity in our Pakistani study group. Read More

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http://dx.doi.org/10.5114/aoms.2018.76946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425217PMC
March 2019
2 Reads

Polymorphisms in , , and genes involved in folate metabolism and thyroid cancer: a case-control study.

Arch Med Sci 2019 Mar 5;15(2):522-530. Epub 2019 Feb 5.

Genetics and Molecular Biology Research Unit - UPGEM, Molecular Biology Department, São José do Rio Preto Medical School - FAMERP, São Paulo, Brazil.

Introduction: Polymorphisms in genes coding enzymes involved in folate metabolism may cause alterations in this metabolic pathway and contribute to carcinogenesis, because folate is essential for DNA synthesis, methylation and repair. The objective of this study was to investigate the association of 677C>T (rs1801133), 2756A>G (rs1805087), 80A>G (rs1051266) and 844ins(68) (no rs#) polymorphisms and thyroid cancer development. The association of these polymorphisms with demographic risk factors and clinical histopathological parameters was also evaluated. Read More

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http://dx.doi.org/10.5114/aoms.2018.73091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425207PMC
March 2019
2 Reads

Long non-coding RNA PCAT-1 promotes tumor progression by inhibiting miR-129-5p in human ovarian cancer.

Arch Med Sci 2019 Mar 30;15(2):513-521. Epub 2018 Apr 30.

Department of Obstetrics-Gynecology, Daqing Oil Field General Hospital, Daqing, Heilongjing, China.

Introduction: Ovarian cancer (OC) is one of the most common malignancies and the leading cause of cancer-related death among women. The long non-coding RNA Prostate cancer-associated transcript-1 (PCAT-1) has been reported to play important roles in multiple human cancers. However, the role of PCAT-1 in OC has never been investigated. Read More

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http://dx.doi.org/10.5114/aoms.2018.75534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425202PMC
March 2019
1 Read

MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients.

Arch Med Sci 2019 Mar 31;15(2):504-512. Epub 2017 Jul 31.

Department of Genetics, Chair of Molecular Medicine, Faculty of Medicine, University of Rzeszow, Rzeszow, Poland.

Introduction: and alterations play a crucial role in glioblastoma (GB) pathogenesis. and function is affected by several pathologic mechanisms, such as point mutations or promoter methylation, which are well characterized. Expression of both genes can be regulated by other mechanisms as well, e. Read More

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http://dx.doi.org/10.5114/aoms.2017.69374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425218PMC
March 2019
2 Reads

Mir-26b inhibits growth and resistance to paclitaxel chemotherapy by silencing the CDC6 gene in gastric cancer.

Arch Med Sci 2019 Mar 7;15(2):498-503. Epub 2018 Feb 7.

Department of Surgical Oncology, First Affiliated Hospital, China Medical University, Shenyang, China.

Introduction: Gastric cancer is one of the most common cancers of the digestive system and is associated with high morbidity and mortality. The aim of this study was to investigate whether miR-26b is involved in the proliferation and resistance to paclitaxel chemotherapy in gastric cancer cells.

Material And Methods: The expression of miR-26b in gastric cancer cell lines was determined by quantitative real-time PCR. Read More

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http://dx.doi.org/10.5114/aoms.2018.73315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425209PMC

Identification of key proteins and lncRNAs in hypertrophic cardiomyopathy by integrated network analysis.

Arch Med Sci 2019 Mar 4;15(2):484-497. Epub 2018 May 4.

Department of Cardiology, Zhejiang Hospital, Hangzhou, Zhejiang Province, China.

Introduction: Hypertrophic cardiomyopathy (HCM), a genetically heterogeneous disorder of cardiac myocytes, is one of the main causes of sudden cardiac death of young people. However, the molecular mechanism involved in HCM has remained largely unclear. Of note, non-coding RNAs were reported to play an important role in human diseases. Read More

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https://www.termedia.pl/doi/10.5114/aoms.2018.75593
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http://dx.doi.org/10.5114/aoms.2018.75593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425197PMC
March 2019
4 Reads

Minocycline impedes mitochondrial-dependent cell death and stabilizes expression of hypoxia inducible factor-1α in spinal cord injury.

Arch Med Sci 2019 Mar 15;15(2):475-483. Epub 2018 Feb 15.

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

Introduction: One of the crucial mechanisms following spinal cord injury is mitochondria-associated cell death. Minocycline, an anti-inflammatory drug, is well known to impede mitochondrial cell death. However, there has been no study on the effect of minocycline linking Fas cell surface death receptor (FAS)-mediated cell death and hypoxia inducible factor (HIF-1α), the targets involved in mitochondrial cell death. Read More

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http://dx.doi.org/10.5114/aoms.2018.73520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425201PMC

Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury.

Arch Med Sci 2019 Mar 4;15(2):467-474. Epub 2019 Mar 4.

Division of Public Health, Faculty of Medicine, İnönü University, Malatya, Turkey.

Introduction: RS100642, a mexiletine analogue, is a novel sodium channel blocker with neuroprotective and antioxidant activities. The protectivity of RS100642, which has been shown against focal cerebral ischemia, was investigated in global cerebral ischemia in this study.

Material And Methods: Global cerebral ischemia was induced for five minutes in adult male Wistar Albino rats via the 4-vessel occlusion method. Read More

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https://www.termedia.pl/doi/10.5114/aoms.2017.72550
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http://dx.doi.org/10.5114/aoms.2017.72550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425206PMC
March 2019
13 Reads

Matrix metalloproteinase-9 and p53 involved in chronic fluorosis induced blood-brain barrier damage and neurocyte changes.

Arch Med Sci 2019 Mar 4;15(2):457-466. Epub 2019 Mar 4.

Department of Spine Surgery, Tianjin Union Medical Center, Tianjin, China.

Introduction: A large number of basic and clinical studies have confirmed that fluoride produces toxic effects on multiple organ systems in the body including the nervous system.

Material And Methods: One hundred twenty Wistar rats were randomly divided into 4 groups with 30 in each group: a high fluoride group (drinking 200 mg/l fluoridated water, 24 weeks); a high fluoride control group (drinking distilled water, 24 weeks); a fluoride removal group (drinking fluoridated water, 12 W; then distilled water, 12 W) and a defluorination control group (drinking distilled water, 24 weeks).

Results: The high fluoride and fluoride removal groups had spinal cord astrocyte edema. Read More

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http://dx.doi.org/10.5114/aoms.2019.83294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425220PMC

Vitreous concentrations of vascular endothelial growth factor as a potential biomarker for postoperative complications following pars plana vitrectomy.

Arch Med Sci 2019 Mar 2;15(2):449-456. Epub 2018 Feb 2.

School of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

Introduction: The aim of the study was to investigate the effects of vascular endothelial growth factor (VEGF) concentration in vitreous on postoperative complications after pars plana vitrectomy (PPV).

Material And Methods: Ninety subjects were surgically treated with PPV and followed up for 12 months at the Clinical Centre University Sarajevo, Clinic for Eye Disease. Exclusion criteria were presence of other eye diseases, systemic acute/chronic inflammatory conditions, or malignant neoplasms; previously performed PPV surgery; previously received intravitreal or systemic anti-VEGF therapy. Read More

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http://dx.doi.org/10.5114/aoms.2018.73208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425199PMC
March 2019
2 Reads

Impact of spider nevus and subcutaneous collateral vessel of chest/abdominal wall on outcomes of liver cirrhosis.

Arch Med Sci 2019 Mar 28;15(2):434-448. Epub 2018 Mar 28.

Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, China.

Introduction: Spider nevus and subcutaneous collateral vessel of the chest/abdominal wall are common in liver cirrhosis. This prospective study aimed to evaluate the impact of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall on the outcomes of cirrhotic patients.

Material And Methods: We prospectively enrolled patients with a diagnosis of liver cirrhosis consecutively admitted to our department. Read More

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http://dx.doi.org/10.5114/aoms.2018.74788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425211PMC
March 2019
1 Read
1.890 Impact Factor

How to improve the adenoma detection rate in colorectal cancer screening? Clinical factors and technological advancements.

Arch Med Sci 2019 Mar 6;15(2):424-433. Epub 2018 Apr 6.

2 Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.

Introduction: Colonoscopy has been widely regarded as the gold standard in colorectal cancer (CRC) screening. Within recent years different endoscopic imaging techniques have been introduced to improve the quality of colonoscopy. The adenoma detection rate (ADR) is the single most important quality indicator for colonoscopy. Read More

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http://dx.doi.org/10.5114/aoms.2018.74863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425210PMC

Expression of tryptophan hydroxylase in gastric mucosa in symptomatic and asymptomatic infection.

Arch Med Sci 2019 Mar 5;15(2):416-423. Epub 2018 Jul 5.

Department of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.

Introduction: infection induces clinical symptoms in 15-20% of subjects, and the reason for this variation is still not clear. The aim of the present study is to evaluate the expression of tryptophan hydroxylase (TpH-1) in gastric mucosa of patients with symptomatic and asymptomatic infection in relation to the intensity of bacterial colonization and severity of dyspeptic symptoms.

Material And Methods: Ninety subjects (aged 35-49 years) were enrolled in the study and separated into 3 groups of 30 subjects each. Read More

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http://dx.doi.org/10.5114/aoms.2018.76928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425205PMC
March 2019
1 Read

Standardised electronic algorithms for monitoring prophylaxis of postoperative nausea and vomiting.

Arch Med Sci 2019 Mar 4;15(2):408-415. Epub 2019 Mar 4.

Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.

Introduction: Despite comprehensive guidelines with high-grade evidence, postoperative nausea and vomiting (PONV) remains a frequent problem in anaesthesia care. Anaesthesia information management systems (AIMS) may aid clinicians in PONV prevention, but their benefit is critically dependent on the details of implementation into practice. This study aimed to examine strengths and weaknesses of the local AIMS-based algorithm in prevention of PONV. Read More

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http://dx.doi.org/10.5114/aoms.2019.83293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425213PMC

Does early removal of double J stents reduce urinary infection in living donor renal transplantation?

Arch Med Sci 2019 Mar 15;15(2):402-407. Epub 2018 Feb 15.

Department of General Surgery and Organ Transplantation, Ankara Güven Hastanesi, Ankara, Turkey.

Introduction: Prophylactic use of double J (DJ) stents in recipients is highly accepted in renal transplantation. In this study, the association between the frequency of urologic complications (UC) and urinary tract infections (UTI), and the early or late removal of DJ stents was investigated.

Material And Methods: A total of 116 live-donor renal transplant patients were included in the study during a 4-year period, with a mean follow-up of 29. Read More

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http://dx.doi.org/10.5114/aoms.2018.73524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425203PMC
March 2019
3 Reads

In patients with superficial vein thrombosis the inflammatory response is increased and related to the recanalization rate.

Arch Med Sci 2019 Mar 4;15(2):393-401. Epub 2019 Mar 4.

Department of Vascular Disease, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Introduction: Little is known about pathogenetic mechanisms of superficial venous thrombosis (SVT). We aimed to investigate the systemic inflammatory response in the acute phase of SVT, the time course of inflammatory markers and involvement of inflammation in resolution of thrombus in SVT.

Material And Methods: The circulatory inflammatory parameters high-sensitivity C-reactive protein (hsCRP), tumor necrosis factor α (TNF-α), interleukins 6, 8 and 10 (IL-6, IL-8, IL-10), and markers of fibrinolytic activity tissue plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1) and fibrinogen were determined in 68 patients with acute SVT of lower limbs, who were allocated to two groups, dalteparin 5000 IU once daily or 10 000 IU once daily. Read More

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http://dx.doi.org/10.5114/aoms.2019.83292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425223PMC
March 2019
1 Read

Beneficial effects of pre-stroke statins use in cardioembolic stroke patients with atrial fibrillation: a hospital-based retrospective analysis.

Arch Med Sci 2019 Mar 4;15(2):385-392. Epub 2019 Mar 4.

Cardiovascular Research Centre, University of Zielona Gora, Zielona Gora, Poland.

Introduction: Statins are widely used in stroke patients. The AHA/ASA guidelines recommend aggressive statin therapy in atherosclerotic stroke patients. Their beneficial effects are due to both their hypolipemic and pleiotropic properties. Read More

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http://dx.doi.org/10.5114/aoms.2019.82925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425215PMC
March 2019
1 Read

Circulating microRNAs as biomarkers for myocardial fibrosis in patients with left ventricular non-compaction cardiomyopathy.

Arch Med Sci 2019 Mar 4;15(2):376-384. Epub 2019 Mar 4.

Department of Radiology and Diagnostic Imaging, Medical University of Lodz, Central Clinical Hospital, Lodz, Poland.

Introduction: Despite the fact that cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) is a proven method for detecting myocardial fibrosis, there is a need for new and reliable serological biomarkers. Circulating miRNAs could be a practical and attractive alternative. The purpose of the study was to assess the miRNAs well established in myocardial fibrosis - miR-21, miR-29a, miR-30d and miR-133a - in the plasma of patients with left ventricular non-compaction (LVNC) that have areas of LGE assessed by CMR. Read More

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https://www.termedia.pl/doi/10.5114/aoms.2019.82919
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http://dx.doi.org/10.5114/aoms.2019.82919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425222PMC
March 2019
3 Reads

Serum lipid metabolism in psoriasis and psoriatic arthritis - an update.

Arch Med Sci 2019 Mar 8;15(2):369-375. Epub 2018 Mar 8.

Department of Paediatric Orthopaedics and Rehabilitation, Medical University of Lublin, Lublin, Poland.

Introduction: Psoriasis and psoriatic arthritis (PSA) are chronic, inflammatory, systemic diseases characterized by metabolic abnormalities, including an increased cardiovascular risk and an oxidative imbalance. This study assessed blood parameters of lipid metabolism and markers of oxidative stress in patients with psoriasis and PSA.

Material And Methods: The study included 93 patients with psoriasis (31 patients with PSA and psoriasis, 62 patients with psoriasis vulgaris), and 60 healthy, age-matched controls. Read More

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http://dx.doi.org/10.5114/aoms.2018.74021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425200PMC
March 2019
2 Reads

Vitamin D level is associated with severity of coronary artery atherosclerosis and incidence of acute coronary syndromes in non-diabetic cardiac patients.

Arch Med Sci 2019 Mar 4;15(2):359-368. Epub 2019 Mar 4.

Department of Cardiology, Bielanski Hospital, Warsaw, Poland.

Introduction: Ischaemic heart disease is the main cause of death in developed countries. There are many modifiable risk factors associated with coronary heart disease (CAD). A growing number of studies point to vitamin D deficiency as a risk factor for heart attacks and the conditions associated with cardiovascular disease. Read More

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http://dx.doi.org/10.5114/aoms.2019.83291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425216PMC
March 2019
1 Read

Higher cardiorespiratory fitness predicts long-term survival in patients with heart failure and preserved ejection fraction: the Henry Ford Exercise Testing (FIT) Project.

Arch Med Sci 2019 Mar 4;15(2):350-358. Epub 2019 Mar 4.

Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, USA.

Introduction: Higher cardiorespiratory fitness (CRF) is associated with improved exercise capacity and quality of life in heart failure with preserved ejection fraction (HFpEF), but there are no large studies evaluating the association of HFpEF, CRF, and long-term survival. We therefore aimed to determine the association between CRF and all-cause mortality, in patients with HFpEF.

Material And Methods: In the Henry Ford Exercise Testing (FIT) Project, 167 patients had baseline HFpEF, defined as a clinical diagnosis of heart failure with ejection fraction ≥ 50% on echocardiogram. Read More

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https://www.termedia.pl/doi/10.5114/aoms.2019.83290
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http://dx.doi.org/10.5114/aoms.2019.83290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425214PMC
March 2019
8 Reads

Flow-mediated dilation can be used to predict incident hypertension in patients with hyperuricemia.

Arch Med Sci 2019 Mar 2;15(2):343-349. Epub 2018 Mar 2.

Department of Endocrinology, Xili People's Hospital of Nanshan District, Shenzhen, China.

Introduction: The aim of the study was to evaluate whether flow-mediated dilation (FMD) can be used to predict incident hypertension in patients with hyperuricemia.

Material And Methods: Normotensive participants with and without hyperuricemia at baseline were prospectively enrolled. Flow-mediated dilation was assessed at baseline, and after 1 year's follow-up the incidence of hypertension was compared between those with and without hyperuricemia. Read More

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http://dx.doi.org/10.5114/aoms.2018.73856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425196PMC
March 2019
2 Reads

Associations of dipping and non-dipping hypertension with cardiovascular diseases in patients with dyslipidemia.

Arch Med Sci 2019 Mar 5;15(2):337-342. Epub 2018 Jan 5.

Department of Emergency, The Third People's Hospital, Huizhou, China.

Introduction: Dyslipidemia combined with hypertension increases the risk of cardiovascular disease (CVD). The current study aimed to investigate the association of dipping and non-dipping hypertension with CVD in patients with dyslipidemia.

Material And Methods: A total of 243 documented dyslipidemia patients with hypertension were enrolled. Read More

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https://www.termedia.pl/doi/10.5114/aoms.2018.72609
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http://dx.doi.org/10.5114/aoms.2018.72609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425204PMC
March 2019
6 Reads

Comparison of the incidence of new malignancies in diabetic patients in urban and rural populations in Poland in the years 2008-2014 based on the database of the National Health Fund.

Arch Med Sci 2019 Mar 5;15(2):330-336. Epub 2017 Oct 5.

Department of Health Care, Center of Postgraduate Medical Education, Warsaw, Poland.

Introduction: Many epidemiological studies show a correlation between the risk of cancer and type 2 diabetes mellitus in various populations.

Material And Methods: The material was obtained from the database of the National Health Fund. This publication presents a comparison of the incidence of new malignancies in rural and urban populations of diabetic patients in Poland based on the database of the National Health Fund for the period between 1. Read More

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http://dx.doi.org/10.5114/aoms.2017.68409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425219PMC
March 2019
2 Reads

Age at onset of obesity, transcription factor 7-like 2 (TCF7L2) rs7903146 polymorphism, adiponectin levels and the risk of type 2 diabetes in obese patients.

Arch Med Sci 2019 Mar 17;15(2):321-329. Epub 2017 Nov 17.

Department of Biochemistry and Pharmacogenomics, Faculty of Pharmacy and Center for Preclinical Studies, Medical University of Warsaw, Warsaw, Poland.

Introduction: Interaction between obesity and genetic factors involved in the regulatory pathways of glucose homeostasis may play a significant role in diabetes development in the obese. The aim of this study was to investigate the associations between the TCF7L2 rs7903146 polymorphism, adiponectin levels, age at onset of obesity and the occurrence of type 2 diabetes (T2D) in a sample of obese Polish adults.

Material And Methods: A total of 474 unrelated obese subjects were included in this study. Read More

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http://dx.doi.org/10.5114/aoms.2017.69638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425208PMC
March 2019
1 Read

MARCH: factors associated with weight loss in patients with newly diagnosed type 2 diabetes treated with acarbose or metformin.

Arch Med Sci 2019 Mar 20;15(2):309-320. Epub 2018 Apr 20.

Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China.

Introduction: In this secondary analysis of the Metformin and AcaRbose in Chinese as the initial Hypoglycaemic treatment (MARCH) trial, we evaluated what demographic and clinical factors were associated with reduction in weight. We also assessed the effects of acarbose and metformin treatment on weight reduction.

Material And Methods: We analyzed the demographic and clinical laboratory values from the 784 patients with type 2 diabetes of the MARCH study who were treated for 48 weeks with acarbose or metformin. Read More

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http://dx.doi.org/10.5114/aoms.2018.75255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425198PMC
March 2019
3 Reads

A systematic review and meta-analysis on the treatment of liver hydatid cyst using meta-MUMS tool: comparing PAIR and laparoscopic procedures.

Arch Med Sci 2019 Mar 2;15(2):284-308. Epub 2018 Mar 2.

Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Introduction: There is an academic debate over surgical treatments of liver hydatid cyst disease. In this study, a systematic review and meta-analysis were carried out in order to evaluate the pros and cons of both PAIR (Puncture, Aspiration, Injection, Respiration) and laparoscopic techniques by considering the outcomes of liver hydatid cysts.

Material And Methods: We designed descriptive Boolean queries to search two databases, PubMed and Scopus, to derive the articles published in the period of January 2000 to December 2016 in order to evaluate the outcomes of these research articles. Read More

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http://dx.doi.org/10.5114/aoms.2018.73344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425195PMC
March 2019
3 Reads
1.890 Impact Factor

Association between circulating leptin concentration and gene polymorphism in patients with breast cancer: a meta-analysis.

Arch Med Sci 2019 Mar 15;15(2):275-283. Epub 2018 May 15.

Department of Oncology, the First Affiliated Hospital of Anhui Medical University, Anhui, China.

Introduction: The aim of this meta-analysis was to summarize the evidence on the serum/plasma leptin concentrations in breast cancer (BC) patients, as well as the associations between leptin gene polymorphisms and susceptibility to BC.

Material And Methods: Potentially relevant studies about serum/plasma leptin levels and leptin gene polymorphism were selected using the electronic databases PubMed, EMBASE and The Cochrane Library (from January 1 1995 to Jun 30 2017, no language restrictions). The potential sources of heterogeneity were assessed by the statistic and quantified using ; publication bias was qualitatively assessed by funnel plot and quantitatively assessed by Egger's linear regression test. Read More

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http://dx.doi.org/10.5114/aoms.2018.75638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425221PMC

Pulmonary hypertension in left heart disease.

Arch Med Sci 2019 Jan 17;15(1):262-273. Epub 2017 Jul 17.

Division of Cardiology, New York Medical College, Valhalla, NY, USA.

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http://dx.doi.org/10.5114/aoms.2017.68938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348356PMC
January 2019

Potential injurious effects of the fine particulate PM2.5 on the progression of atherosclerosis in apoE-deficient mice by activating platelets and leukocytes.

Arch Med Sci 2019 Jan 30;15(1):250-261. Epub 2018 Dec 30.

Hebei North University, Hebei, China.

Introduction: Exposure to the fine particulate matter PM2.5 is strongly associated with atherosclerotic diseases, creating considerable public concern. Nevertheless, the mechanisms have not been fully elucidated. Read More

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https://www.termedia.pl/doi/10.5114/aoms.2018.81039
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http://dx.doi.org/10.5114/aoms.2018.81039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348359PMC
January 2019
8 Reads

administration of quercetin ameliorates sperm oxidative stress, inflammation, preserves sperm morphology and functions in streptozotocin-nicotinamide induced adult male diabetic rats.

Arch Med Sci 2019 Jan 30;15(1):240-249. Epub 2018 Dec 30.

Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Introduction: Diabetes mellitus (DM) has been associated with sperm damage. In view of the fact that quercetin possesses antioxidant and anti-inflammatory activities, this compound may help to protect sperm against damage in DM. In this study, effects of quercetin on sperm parameters in DM were investigated. Read More

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http://dx.doi.org/10.5114/aoms.2018.81038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348351PMC
January 2019
1 Read

Ethyl pyruvate treatment ameliorates pancreatic damage: evidence from a rat model of acute necrotizing pancreatitis.

Arch Med Sci 2019 Jan 23;15(1):232-239. Epub 2017 Jan 23.

Department of Surgery, Samsun State Hospital, Samsun, Turkey.

Introduction: Ethyl pyruvate (EP), a natural flavoring and fragrance agent, has been shown to exert anti-inflammatory and antioxidant actions. We tested the potential beneficial effects of EP in a rat model of acute necrotizing pancreatitis (ANP), a serious condition with a significant inflammatory explosion and oxidative stress.

Material And Methods: Fifty-two adult male Sprague-Dawley rats were divided into four groups: sham + saline, sham + EP, ANP + saline, and ANP + EP. Read More

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http://dx.doi.org/10.5114/aoms.2017.65231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348362PMC
January 2019
1 Read

effect of methanolic extract on stress-induced gastric ulcers in rats.

Arch Med Sci 2019 Jan 19;15(1):223-231. Epub 2016 Oct 19.

Department of Pharmacology, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia.

Introduction: (Piperaceae) is traditionally used by Asians to treat numerous common ailments including asthma, fever and gastritis. The aim of the research was to determine and compare the effects of Piper sarmentosum (PS) with omeprazole (OMZ) on gastric parameters in rats exposed to restraint stress.

Material And Methods: The methanolic extract of PS was prepared in the dose of 500 mg/kg. Read More

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http://dx.doi.org/10.5114/aoms.2016.63156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348366PMC
January 2019
7 Reads

BDNF contributes to the skeletal muscle anti-atrophic effect of exercise training through AMPK-PGC1α signaling in heart failure mice.

Arch Med Sci 2019 Jan 30;15(1):214-222. Epub 2018 Dec 30.

Department of Emergency, Xin Hua Hospital affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China.

Introduction: Exercise training is a coadjuvant therapy in preventive cardiology, and it delays cardiac dysfunction and exercise intolerance in heart failure (HF). However, the mechanisms underlying muscle function improvement and cardioprotection are poorly understood. In this study, we tested whether exercise training would counteract skeletal muscle atrophy via activation of the BDNF pathway in myocardial infarction (MI)-induced HF mice. Read More

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http://dx.doi.org/10.5114/aoms.2018.81037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348347PMC
January 2019

Trichostatin A activates FOXO1 and induces autophagy in osteosarcoma.

Arch Med Sci 2019 Jan 2;15(1):204-213. Epub 2018 Mar 2.

Department of Oncology, Clinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.

Introduction: Histone deacetylase inhibitors (HDACIs) inhibit human osteosarcoma growth and cause apoptosis. Previously, we reported that HDACIs induce autophagy via the FOXO1 pathway. Whether there is involvement of autophagy in anti-osteosarcoma activity of HDACIs is still unknown. Read More

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http://dx.doi.org/10.5114/aoms.2018.73860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348367PMC
January 2019
1.890 Impact Factor

Stilbene glycoside protects osteoblasts against oxidative damage via Nrf2/HO-1 and NF-κB signaling pathways.

Arch Med Sci 2019 Jan 28;15(1):196-203. Epub 2018 Nov 28.

The First Department of Orthopedics Ward, First People's Hospital of Yuyao, Yuyao, Zhejiang, China.

Introduction: Oxidative stress is currently proposed as a risk factor associated with the development and progression of osteoporosis. Here, the effect of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glycoside (THSG) on oxidative damage was investigated in an osteoblast-like MC3T3-E1 cell model.

Material And Methods: In this study, MC3T3-E1 cells were treated with hydrogen peroxide (HO) (100 µM) and THSG (20, 50 and 100 μM), and alkaline phosphatase (ALP). Read More

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http://dx.doi.org/10.5114/aoms.2018.79937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348355PMC
January 2019
1 Read

The effect of splenectomy on complement regulatory proteins in erythrocytes in β-thalassemia major.

Arch Med Sci 2019 Jan 30;15(1):191-195. Epub 2018 Dec 30.

Department of Medical Oncology, Antalya Education and Research Hospital, Antalya, Turkey.

Introduction: Hemolysis due to ineffective erythropoiesis is a serious problem β-thalassemia major (β-TM) patients. The role of complement system in the etiopathogenesis of hemolysis observed in β-TM were released. Hemolysis induced by activation of complement system is prevented by complement regulatory proteins. Read More

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http://dx.doi.org/10.5114/aoms.2018.81036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348341PMC
January 2019
2 Reads

Roles of miR-210 in the pathogenesis of pre-eclampsia.

Arch Med Sci 2019 Jan 2;15(1):183-190. Epub 2018 Feb 2.

Third Department of Obstetrical, Hebei Cangzhou Central Hospital, Hebei, China.

Introduction: This study aimed to explore the bio-function of miR-210 in the pathogenesis of pre-eclampsia and provide new insights into the diagnosis and treatment of pre-eclampsia.

Material And Methods: A JAR cell line cultured in standard or hypoxic conditions was used in this study. Expression levels of miR-210 and PTPN2 were determined using real-time polymerase chain reaction (RT-PCR). Read More

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https://www.termedia.pl/doi/10.5114/aoms.2018.73129
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http://dx.doi.org/10.5114/aoms.2018.73129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348360PMC
January 2019
6 Reads

Antiproliferative and apoptotic activity of glycyrrhizinic acid in MCF-7 human breast cancer cells and evaluation of its effect on cell cycle, cell migration and m-TOR/PI3K/Akt signalling pathway.

Arch Med Sci 2019 Jan 8;15(1):174-182. Epub 2018 Nov 8.

Departments of General Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, China.

Introduction: Glycyrrhizinic acid is a natural product of pharmacological relevance and its anticancer activity against breast cancer cell lines has not been evaluated. Therefore the main purpose of the present study was to investigate the anticancer effects of glycyrrhizinic acid in MCF-7 human breast cancer cells.

Material And Methods: The MTT assay was used to evaluate the anticancer effects while a clonogenic assay was used to study its effects on colony formation tendency. Read More

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http://dx.doi.org/10.5114/aoms.2018.79429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348358PMC
January 2019
1 Read

FAM40A alters the cytoskeleton of podocytes in familial focal and segmental glomerulosclerosis by regulating F-actin and nephrin.

Arch Med Sci 2019 Jan 2;15(1):165-173. Epub 2018 Feb 2.

Division of Nephrology, Shanghai Changzheng Hospital of Second Military Medical University, Kidney Institute of Chinese People's Liberation Army, Shanghai, China.

Introduction: Familial focal and segmental glomerulosclerosis (FFSGS) was found in a large cohort of patients in our previous study. Under the sponsorship of the National Natural Science Foundation of China, we conducted linkage analysis and full exon sequencing on the genomes of 54 patients diagnosed with FFSGS. The results revealed a FAM40A gene signature in those patients. Read More

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http://dx.doi.org/10.5114/aoms.2018.73138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348344PMC
January 2019
4 Reads

Renin-angiotensin system inhibitor attenuates oxidative stress induced human coronary artery endothelial cell dysfunction via the PI3K/AKT/mTOR pathway.

Arch Med Sci 2019 Jan 8;15(1):152-164. Epub 2018 Mar 8.

Department of Neurology, the BaZhou People's Hospital of XinJiang Uygur Autonomous Region, XinJiang Uygur Autonomous Region, China.

Introduction: The renin-angiotensin system is associated with blood pressure regulation, inflammation, oxidative stress and insulin resistance. It can decrease intracellular oxidative stress. Stimulation with HO leads to increased oxidative stress and activation of the AKT/mTOR pathway. Read More

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http://dx.doi.org/10.5114/aoms.2018.74026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348342PMC
January 2019
4 Reads

Topical morphine for treatment of cancer-related painful mucosal and cutaneous lesions: a double-blind, placebo-controlled cross-over clinical trial.

Arch Med Sci 2019 Jan 2;15(1):146-151. Epub 2018 Jan 2.

Paliative Care Unit, Oncology Chair, Medical University of Lodz, Lodz, Poland.

Introduction: Painful mucosal and cutaneous lesions are often less responsive or even refractory to systemic opioid analgesics. There is evidence suggesting that the effectiveness of topical morphine be restricted to inflammatory pain. The studied groups were small and the observation period relatively short. Read More

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http://dx.doi.org/10.5114/aoms.2018.72566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348368PMC
January 2019

Evaluation of inflammatory response in patients undergoing surgical treatment for early and delayed femoral fractures.

Arch Med Sci 2019 Jan 17;15(1):141-145. Epub 2016 Oct 17.

Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Science, Tehran, Iran.

Introduction: It has been shown that long bone fractures are correlated with the inflammatory response. In the initial injury, surgical reduction and fixation of fractures induce the immunoinflammatory response. This study aimed to evaluate serum variation of inflammatory markers in patients undergoing surgical treatment for early and delayed femoral fractures. Read More

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http://dx.doi.org/10.5114/aoms.2016.63013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348352PMC
January 2019

Prevalence and clinical characteristics of rheumatoid arthritis in Poland: a nationwide study.

Arch Med Sci 2019 Jan 13;15(1):134-140. Epub 2017 Dec 13.

Department of Rheumatology and Internal Medicine, Wroclaw Medical University, Wroclaw, Poland.

Introduction: There are no reliable data regarding the prevalence of rheumatoid arthritis (RA) in Poland.

Material And Methods: The first stage was a face-to-face survey on a nationwide representative sample of 3000 people, which identified respondents with a physician-confirmed diagnosis of RA. The second stage was a survey of RA patients, which characterized the disease course and treatment. Read More

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http://dx.doi.org/10.5114/aoms.2017.71371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348369PMC
January 2019
3 Reads

Amplitude of low-frequency fluctuations in childhood-onset schizophrenia with or without obsessive-compulsive symptoms: a resting-state functional magnetic resonance imaging study.

Arch Med Sci 2019 Jan 12;15(1):126-133. Epub 2018 Feb 12.

Department of Psychiatry, The Second Affiliated Hospital Of Xinxiang Medical University, Henan Mental Hospital, Xinxiang, Henan, China.

Introduction: Childhood-onset schizophrenia with obsessive-compulsive symptoms (COSO) and without obsessive-compulsive symptoms (COS) share considerable overlap in clinical features and genetic risk factors. However, the extent of brain functional abnormalities in COSO and COS is poorly understood.

Material And Methods: A total of 51 first-episode childhood schizophrenic patients and 30 healthy age- and sex-matched controls were recruited. Read More

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http://dx.doi.org/10.5114/aoms.2018.73422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348357PMC
January 2019

Lipid levels and selected biomarkers of vascular changes in children with idiopathic headaches - a preliminary report.

Arch Med Sci 2019 Jan 2;15(1):120-125. Epub 2018 Mar 2.

Department of Paediatrics and Paediatric Endocrinology, School of Medicine, Medical University of Silesia, Katowice, Poland.

Introduction: Elevated lipid concentrations were observed in adults with headaches. However, studies in children are scarce. Recent data suggest new potential risk factors for atherosclerosis, which may be associated with headaches. Read More

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http://dx.doi.org/10.5114/aoms.2018.73983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348343PMC
January 2019

Evaluation of FGF-19 and β-klotho as biomarkers in patients with intrahepatic cholestasis of pregnancy.

Arch Med Sci 2019 Jan 10;15(1):113-119. Epub 2018 Jan 10.

Department of Obstetrics and Gynecology, Health Sciences University Zeynep Kamil Maternity and Children's Research Hospital, Istanbul, Turkey.

Introduction: Fibroblast growth factor-19 (FGF-19) and its co-receptor, beta-klotho, regulate bile acid synthesis in the liver as an enterohepatic feedback mechanism. In this study, our aim was to investigate the circulating FGF-19 and β-klotho levels in intrahepatic cholestasis of pregnancy (ICP) cases.

Material And Methods: A cross-sectional study including 40 women whose pregnancies were complicated with ICP were recruited for the study group. Read More

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http://dx.doi.org/10.5114/aoms.2017.72424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348354PMC
January 2019
4 Reads

An evaluation of the usefulness of extracorporeal liver support techniques in patients with severe liver dysfunction.

Arch Med Sci 2019 Jan 25;15(1):99-112. Epub 2017 May 25.

Department of Anaesthesiology and Intensive Therapy - Centre for Artificial Extracorporeal Kidney and Liver Support, Dr Wł. Biegański Regional Specialist Hospital, Lodz, Poland.

Introduction: The mortality rate in patients with severe liver dysfunction with no option of transplantation is unacceptably high. The main aim of this study was to evaluate the usefulness of applying extracorporeal liver support (ECLS) techniques in this group of patients.

Material And Methods: Data from hospital admissions of 101 patients with severe liver dysfunction who were admitted to the department of Anaesthesiology and intensive therapy between 2006 and 2015 were retrospectively analysed. Read More

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http://dx.doi.org/10.5114/aoms.2017.67998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348365PMC
January 2019
1 Read