1,853 results match your criteria Archives of medical science : AMS[Journal]


Arguable ICD placement in a sarcoidosis patient with extensive cardiac involvement.

Arch Med Sci 2020 18;16(3):707-708. Epub 2019 Jul 18.

Department of Noninvasive Cardiac Diagnostics, Medical University of Gdansk, Gdansk, Poland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.86708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212219PMC

Effect of β-asarone in normal and β-amyloid-induced Alzheimeric rats.

Arch Med Sci 2020 25;16(3):699-706. Epub 2020 Apr 25.

Department of Biology, Fars Science and Research Branch, Islamic Azad University, Fars, Iran.

Introduction: β-Asarone is a major component of Schott. It has pharmacological effects that include antihyperlipidemic, anti-inflammatory, and antioxidant activity. In the present study, the effect of β-asarone on neurodegeneration induced by intrahippocampal administration of β-amyloid was investigated in adult male Wistar rats. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212238PMC

Correlation between sperm mitochondrial ND5 and ND6 gene variations and total fertilisation failure.

Arch Med Sci 2020 25;16(3):692-698. Epub 2020 Apr 25.

Reproductive Medical Center, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.

Introduction: The purpose of this study was to investigate the correlation between sperm mitochondrial NADH dehydrogenase subunit 5 (ND5) and NADH dehydrogenase subunit 6 (ND6) gene variations and total fertilisation failure (TFF).

Material And Methods: A total of 232 sperm samples at the fresh in vitro fertilisation (IVF) cycle or the half-intracytoplasmic sperm injection (ICSI) cycle were collected for this retrospective controlled study on Han Chinese people between July 2011 and April 2014. Of the 232 total samples, 45 were from the IVF-TFF group and 187 were from couples with normal fertilisation (fertilisation rate > 50%). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212212PMC

Analysis of the association between the XRCC2 rs3218536 polymorphism and ovarian cancer risk.

Arch Med Sci 2020 25;16(3):682-691. Epub 2020 Apr 25.

Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Ji'nan, Shandong, China.

Introduction: Results conflict on the association between the XRCC2 rs3218536 polymorphism and ovarian cancer risk, despite wide-ranging investigations. This meta-analysis examines whether the XRCC2 rs3218536 polymorphism is associated with ovarian cancer risk.

Material And Methods: Eligible case-control studies were searched in PubMed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212224PMC

Exposure to biomass smoke, cigarettes, and alcohol modifies the association between (, -) polymorphisms and tuberculosis in Mexican carriers.

Arch Med Sci 2020 31;16(3):672-681. Epub 2020 Jan 31.

Department of Pathology, National Institute of Neurology and Neurosurgery Manuel Velasco Suarez, Mexico City, Mexico.

Introduction: Exposure to biomass smoke, cigarettes, alcohol, and the impairment of immunoregulation are considered to be risk factors for tuberculosis. () - and - gene polymorphisms have been associated with tuberculosis. However, the results remain inconsistent. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.92673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212218PMC
January 2020
1.890 Impact Factor

Assessment of selected nutrient intake by Polish preschool children compared to dietary recommendations: a meta-analysis.

Arch Med Sci 2020 12;16(3):635-647. Epub 2020 Feb 12.

Department of Physical Activity Study and Health Promotion, Poznan University of Physical Education, Poznan, Poland.

Introduction: In recent years a steady increase in the number of obese people has been observed worldwide. This problem is also increasingly applicable to children and adolescents. In this study, we conducted a meta-analysis of studies carried out in Poland over ten years (2005-2015) which analysed the diet of preschool children and assessed how significantly it affects the prevention of diet-dependent disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.93046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212230PMC
February 2020

Chronic pain and use of analgesics in the elderly: a nationwide population-based study.

Arch Med Sci 2020 11;16(3):627-634. Epub 2020 Feb 11.

Department of Geriatrics and Gerontology, Chi-Mei Medical Center, Tainan, Taiwan.

Introduction: Chronic pain may cause many comorbidities in the elderly; however, nationwide data about this issue remain insufficient. We conducted this study to address the data gap.

Material And Methods: We identified geriatric participants (≥ 65 years) with chronic pain between 2000 and 2013 from the Taiwan National Health Insurance Research Database. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.92894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212229PMC
February 2020

Effect of tranexamic acid on symptomatic venous thromboembolism in patients undergoing primary total knee arthroplasty.

Arch Med Sci 2020 19;16(3):603-612. Epub 2020 Jan 19.

Department of Orthopedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Introduction: This study aimed to investigate the effect of tranexamic acid (TXA) with sequential routine anticoagulation on postoperative symptomatic venous thromboembolism (VTE) in patients undergoing primary total knee arthroplasty (TKA).

Material And Methods: This was a prospective study with randomized trials. From January 2013 to May 2015, 1880 patients undergoing primary TKA were enrolled in this study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.92444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212233PMC
January 2020

Dynamic thiol and disulphide homoeostasis in fibromyalgia.

Arch Med Sci 2020 15;16(3):597-602. Epub 2019 Aug 15.

Department of Biochemistry, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey.

Introduction: Thiol and disulphide levels are biomarkers that provide useful information about oxidative stress and antioxidant capacity, showing a different homoeostasis in inflammatory and proliferative diseases. We aimed to clarify the possible aetiology of this disease by using thiol and disulphide levels in patients with fibromyalgia, the basis of which has not yet been clearly elucidated.

Material And Methods: A total of 156 individuals: 86 patients with fibromyalgia and 70 age-matched controls were included in this prospective non-randomised case-control study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.87052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212223PMC

Peptide-based formula versus standard-based polymeric formula for critically ill children: is it superior for patients' tolerance?

Arch Med Sci 2020 6;16(3):592-596. Epub 2020 Apr 6.

Ain Shams University, Cairo, Egypt.

Introduction: Malnutrition affects 50% of hospitalized children and 25-70% of critically ill children. Enteral tube feeding is generally considered the preferred modality for critically ill pediatric patients. Clinical advantages of using peptide-based formulas are still controversial in critically ill children. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212209PMC

The telomere length of gastric mucosal samples and peripheral blood lymphocytes in patients who have undergone Billroth II distal gastrectomy.

Arch Med Sci 2020 25;16(3):577-583. Epub 2020 Apr 25.

Department of Gastroenterology, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.

Introduction: Telomeres play an important role in maintaining chromosomal integrity. Functional loss of telomeres increases the risk of cancer by causing genomic instability. Telomere length abnormalities have been reported in several precancerous lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212211PMC

Acute kidney injury in critically ill cirrhotic patients with spontaneous bacterial peritonitis: a comparison of KDIGO and ICA criteria.

Arch Med Sci 2020 17;16(3):569-576. Epub 2019 May 17.

Department of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, China.

Introduction: Acute kidney injury (AKI) is an important independent predictor of mortality in cirrhotic patients with spontaneous bacterial peritonitis (SBP). However, the definition of AKI in cirrhosis has been debated for many years. This study aims to compare the prediction accuracy of Kidney Disease: Improving Global Outcomes (KDIGO) and International Club of Ascites (ICA) criteria for hospital mortality in cirrhotic patients with SBP admitted to the intensive care unit (ICU). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.85148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212228PMC

A new electrocardiographic parameter associated with sudden cardiac death in pulmonary sarcoidosis.

Arch Med Sci 2020 9;16(3):559-568. Epub 2019 Oct 9.

Department of Cardiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Introduction: The interval from the peak to the end of the electrocardiographic T wave (T-T) may correspond to malignant ventricular arrhythmias. In this study we aimed to assess T-T variability and investigate the transmural dispersion of repolarisation in pulmonary sarcoidosis disease without proofed cardiac involvement.

Material And Methods: This was a retrospective case-control study that included patients who had a pathologic and radiologic diagnosis of sarcoidosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.88393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212222PMC
October 2019

Managed Care after Acute Myocardial Infarction (KOS-zawał) reduces major adverse cardiovascular events by 45% in 3-month follow-up - single-center results of Poland's National Health Fund program of comprehensive post-myocardial infarction care.

Arch Med Sci 2020 6;16(3):551-558. Epub 2019 Jun 6.

First Department of Cardiology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

Introduction: Despite progress in medical and interventional treatment of acute myocardial infarction (AMI) resulting in low in-hospital mortality, the post-discharge prognosis in MI survivors is still unacceptable. The Managed Care in Acute Myocardial Infarction (MC-AMI, KOS-zawał) is a program introduced by Poland's National Health Fund aiming at comprehensive care for patients with AMI to improve prognosis. It includes acute intervention, complex revascularization, cardiac rehabilitation (CR), scheduled outpatient follow-up, and prevention of sudden cardiac death. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.85649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212237PMC

Association of anti-hyperuricemia treatment and prevalent cardiovascular disease in hypertensive patients.

Arch Med Sci 2020 11;16(3):545-550. Epub 2019 Apr 11.

Department of Cardiology, FuWai Hospital Chinese Academic of Medical Science, Shenzhen, Guangdong, China.

Introduction: The current study aimed to evaluate the association of anti-hyperuricemia treatment and prevalent cardiovascular disease (CVD) in hypertensive patients.

Material And Methods: Primary hypertensive patients with hyperuricemia were enrolled. All participants were separated into two groups: anti-hyperuricemia and control groups (without anti-hyperuricemia treatment). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.84397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212227PMC

Association of masked uncontrolled hypertension and cardiovascular diseases in treated hypertensive patients.

Arch Med Sci 2020 30;16(3):538-544. Epub 2019 Oct 30.

Department of Endocrinology and Metabolism, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, China.

Introduction: The aim of the study was to evaluate the association of masked uncontrolled hypertension (MUCH) and prevalence of cardiovascular disease in treated hypertensive patients.

Material And Methods: Patients' demographics and prior medical histories were collected. Fasting venous blood was drawn for evaluation of serum creatinine level, which was used to calculate glomerular filtration rate (GFR). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.89218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212231PMC
October 2019

Evaluation of atherogenic laboratory markers in Behçet's disease patients with vascular involvement.

Arch Med Sci 2020 27;16(3):531-537. Epub 2019 Oct 27.

Department of Clinical Biochemistry, Ankara Gülhane Training and Research Hospital, Etlik, Ankara, Turkey.

Introduction: Behçet's disease is a chronic inflammatory vasculitis presenting with immunological and endothelial changes. The aim of the present study is to evaluate blood levels of diagnostic markers which can be used in Behçet's patients with vascular involvement.

Material And Methods: Fifty Behçet's patients (22 with vascular involvement) and 30 healthy controls were included in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2018.79139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212210PMC
October 2019

Difference in hematocrit and plasma albumin levels as an additional biomarker in the diagnosis of infectious disease.

Arch Med Sci 2020 25;16(3):522-530. Epub 2019 Jul 25.

Department of Intensive Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.

Introduction: In clinical practice, it has been observed that patients with severe infections show changes to their hematocrit (HCT) and serum albumin (ALB) levels. This study aimed to evaluate whether the difference of HCT and ALB (HCT-ALB) levels can be used as an additional biomarker for fast diagnosis of severe infections.

Material And Methods: This was a retrospective case-control study which included adult patients with severe infections, patients with non-infective conditions and healthy individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.86898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212220PMC

State-of-the-art tools unveil potent drug targets amongst clinically approved drugs to inhibit helicase in SARS-CoV-2.

Arch Med Sci 2020 17;16(3):508-518. Epub 2020 Apr 17.

Department of Genetic Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Introduction: The extreme health and economic problems in the world due to the SARS-CoV-2 infection have led to an urgent need to identify potential drug targets for treating coronavirus disease 2019 (COVID-19). The present state-of-the-art tool-based screening was targeted to identify drug targets among clinically approved drugs by uncovering SARS-CoV-2 helicase inhibitors through molecular docking analysis.

Material And Methods: Helicase is a vital viral replication enzyme, which unwinds nucleic acids and separates the double-stranded nucleic acids into single-stranded nucleic acids. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212215PMC
April 2020
1.890 Impact Factor

State-of-the-art tools to identify druggable protein ligand of SARS-CoV-2.

Arch Med Sci 2020 27;16(3):497-507. Epub 2020 Mar 27.

Department of Genetic Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Introduction: The SARS-CoV-2 (previously 2019-nCoV) outbreak in Wuhan, China and other parts of the world affects people and spreads coronavirus disease 2019 (COVID-19) through human-to-human contact, with a mortality rate of > 2%. There are no approved drugs or vaccines yet available against SARS-CoV-2.

Material And Methods: State-of-the-art tools based on in-silico methods are a cost-effective initial approach for identifying appropriate ligands against SARS-CoV-2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212236PMC
March 2020
1.890 Impact Factor

Statins and the COVID-19 main protease: evidence on direct interaction.

Arch Med Sci 2020 25;16(3):490-496. Epub 2020 Apr 25.

Halal Research Center of IRI, FDA, Tehran, Iran.

Introduction: No proven drug and no immunisation are yet available for COVID-19 disease. The SARS-CoV-2 main protease (Mpro), a key coronavirus enzyme, which is a potential drug target, has been successfully crystallised. There is evidence suggesting that statins exert anti-viral activity and may block the infectivity of enveloped viruses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212226PMC
April 2020
1.890 Impact Factor

Lipid-lowering therapy and renin-angiotensin-aldosterone system inhibitors in the era of the COVID-19 pandemic.

Arch Med Sci 2020 14;16(3):485-489. Epub 2020 Apr 14.

Department of Clinical Biochemistry, Royal Free Hospital campus, University College London Medical School, University College London (UCL), London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.94503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212217PMC

The significance of chemokine CXCL-8 in esophageal carcinoma.

Arch Med Sci 2020 4;16(2):475-480. Epub 2020 Feb 4.

Department of Neurodegeneration Diagnostics, Medical University of Bialystok, Bialystok, Poland.

Chemokines are a group of small molecular weight proteins that are structurally related. These molecules play an important role in the growth, differentiation and activation of many types of cells [1, 2]. Chemokines are synthesized mostly by leukocytes and act through their cognate G-protein coupled receptors to cause a cellular response, such as migration, adhesion or chemotaxis [1, 3]. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2017.71933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069419PMC
February 2020

Successful endoscopic treatment of walled-off pancreatic necrosis complicated with pancreaticopleural and pancreaticocolonic fistulas.

Arch Med Sci 2020 4;16(2):471-474. Epub 2020 Feb 4.

Department of General, Gastroenterological and Oncological Surgery, Collegium Medicum, Nicolaus Copernicus University, Torun, Poland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2017.70658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069431PMC
February 2020

The functional evaluation of pituitary in patients with a surgical resection of sellar tumours.

Arch Med Sci 2020 29;16(2):460-465. Epub 2019 Oct 29.

Department of Endocrinology, Xiangya Hospital, Central South University, Changsha, China.

Introduction: The aim of this study was to analyse the incidences of hypopituitarism before and after surgical resection of sellar tumours and to find the factors related to the incidences.

Material And Methods: From January 2009 to December 2011, 191 patients in the Department of Neurosurgery in Xiangya Hospital, who underwent the surgical resection of sellar tumours, were included in this retrospective analysis. Pre- and postoperative pituitary function assessments were performed by the detection of hormone levels. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.89356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069440PMC
October 2019

Identification of seven novel variants in the β-globin gene in transfusion-dependent and normal patients.

Arch Med Sci 2020 5;16(2):453-459. Epub 2019 May 5.

Department of Genetic Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Introduction: Abnormality in results in an inherited recessive blood disorder, which can be caused by variants at the transcriptional or translational level affecting the stability and the production of the HBB chain. The severity of the disease relies on the variant's characteristics. This study aimed to identify the common β-globin variants in the population of the Eastern Province, which has the highest prevalence of blood diseases in Saudi Arabia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.84825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069418PMC
May 2019
1.890 Impact Factor

Eriodictyol exerts potent anticancer activity against A549 human lung cancer cell line by inducing mitochondrial-mediated apoptosis, G2/M cell cycle arrest and inhibition of m-TOR/PI3K/Akt signalling pathway.

Arch Med Sci 2020 17;16(2):446-452. Epub 2019 May 17.

Department of Emergency, The Affiliated Hospital of Panzhihua University, Panzhihua, China.

Introduction: Eriodictyol is an important flavonoid and is commonly present across the plant kingdom. Flavonoids have been reported to show incredible pharmacological potential. However, the anticancer activity of the important flavonoid eriodictyol has not been well reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.85152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069446PMC

MicroRNA-490-3p suppresses hepatocellular carcinoma cell proliferation and migration by targeting the aurora kinase A gene ().

Arch Med Sci 2020 31;16(2):395-406. Epub 2019 Dec 31.

Department of Radiology, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, China.

Introduction: Hepatocellular carcinoma (HCC) is the most common and prevalent cancer type among liver cancers. In this study, expression of miR-490-3p and aurora kinase A gene () was investigated in HCC. Additionally, we explored the microRNA (miR)-490-3p/ relationship as well as the influence on HCC cell proliferation and migration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.91351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069437PMC
December 2019

Identification of key pathways and genes in nonalcoholic fatty liver disease using bioinformatics analysis.

Arch Med Sci 2020 2;16(2):374-385. Epub 2020 Mar 2.

Department of Gastroenterology, Zhongshan Hospital affiliated to Xiamen University, Xiamen, Fujian, China.

Introduction: Nonalcoholic fatty liver disease (NAFLD) is one of the most common types of liver disease in the world. However, the molecular mechanisms regulating the development of NAFLD have remained unclear.

Material And Methods: In the present study, we analyzed two public datasets (GSE48452 and GSE89632) to identify differentially expressed mRNAs in the progression of NAFLD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.93343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069441PMC

Long-term outcomes and prognostic factors of young patients with mucinous and signet-ring cell colorectal cancer.

Arch Med Sci 2020 2;16(2):359-365. Epub 2020 Mar 2.

Department of Colorectal Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning Province, China.

Introduction: The aim of the study was to assess the clinico-pathological features and prognosis of mucinous adenocarcinoma (MAC) and signet-ring cell carcinoma (SRC) in young colorectal cancer (CRC) patients.

Material And Methods: We retrospectively evaluated the patient records of young patients with MAC and SRC (aged ≤ 40 years) treated at the Cancer Hospital of China Medical University from January 2006 to December 2013. Kaplan-Meier analysis and log-rank testing were performed to estimate overall survival (OS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.93342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069433PMC

Ultrastructure of gap junction and Cx43 expression in gastric cancer tissues of the patients.

Arch Med Sci 2020 4;16(2):352-358. Epub 2020 Feb 4.

Department of Pathology, The Affiliated Hospital of Chengde Medical College, Chengde, Hebei, China.

Introduction: Gap junctions are intercellular channels formed by connexin facilitating communication between cells by allowing transfer of ions and small signaling molecules. Connexin 43 (Cx43) is the most ubiquitous connexin in human tissues. Ample evidence suggests the role of gap junction and its connexins such as connexin 43 in human cancers including gastric cancer, which has an important place in the worldwide incidence of cancer and cancer-related deaths. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.92859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069450PMC
February 2020

Homogeneous Group approach to Elixhauser comorbidity for hospital death using administrative data.

Arch Med Sci 2020 1;16(2):321-336. Epub 2019 Aug 1.

Analyses and Strategy Department, Ministry of Health, Warsaw, Poland.

Introduction: The purpose of this study was to introduce a measure of patient's burden based on Elixhauser's comorbidity index. The mentioned measure needed to be based solely on administrative data and be applicable to all specialisations of hospital treatment. Moreover, the intention was to validate the estimation power of the models based on the groups of hospitalisations which were similar with respect to the primary diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.87017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069442PMC

Transfusion-transmitted infections in hemophilia patients who underwent surgical treatment: a study from a single center in north China.

Arch Med Sci 2020 11;16(2):308-312. Epub 2020 Feb 11.

Department of Orthopedic Surgery, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Introduction: Transfusion-transmitted infections (TTIs) continue to be a major challenge among hemophilia patients. This study was conducted to investigate the prevalence of TTIs including hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV) and syphilis in patients with hemophilia who received surgical treatment due to bone or joint lesions in the Department of Orthopedics.

Material And Methods: The present study was conducted from July 1996 to November 2016 in Beijing, China. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.92892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069421PMC
February 2020

RIVAroxaban TWICE daily for lysis of thrombus in the left atrial appendage in patients with non-valvular atrial fibrillation: the RIVA-TWICE study.

Arch Med Sci 2020 12;16(2):289-296. Epub 2019 Jul 12.

Postgraduate Medical School, Department of Cardiology, Grochowski Hospital, Warsaw, Poland.

Introduction: Rivaroxaban is a direct factor Xa inhibitor used once a day for prevention of thrombotic events in patients with atrial fibrillation (AF). However, in a small proportion of subjects thrombus in the left atrial appendage (LAA) is present despite this treatment. The aim of this study was assess the efficacy of increased dose of rivaroxaban (15 mg twice daily) treatment for lysis of thrombus in the LAA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.86616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069443PMC

Takotsubo syndrome - fatal prognosis of patients with low body mass index in 5-year follow-up.

Arch Med Sci 2020 8;16(2):282-288. Epub 2019 Aug 8.

Department of Invasive Cardiology, Medical University of Bialystok, Bialystok, Poland.

Introduction: The clinical courses of takotsubo syndrome (TS) and of acute coronary syndromes (ACS) seem to be very similar. However, there is limited knowledge about risk factors of poor outcomes. Low body mass index worsens the prognosis of patients with cardiovascular diseases, especially those undergoing surgical treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.87082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069448PMC

Potato consumption is associated with total and cause-specific mortality: a population-based cohort study and pooling of prospective studies with 98,569 participants.

Arch Med Sci 2020 11;16(2):260-272. Epub 2020 Feb 11.

Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland.

Introduction: The long-term effect of potato consumption on mortality and cardiovascular (CV) and cardiometabolic risk factors is still largely unknown. Using the National Health and Nutrition Examination Surveys (NHANES) 1999-2010, we evaluted the long-term impact of potato intake on total and cause-specific (cardiovascular disease (CVD), cerebrovascular disease and cancer) mortality, and the results were next validated in a systematic review and meta-analysis of cohort studies investigating pooled associations of potato consumption with all-cause and cause-specific death.

Material And Methods: Vital status up to December 31, 2011 was ascertained in NHANES. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.92890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069422PMC
February 2020

A pooled analysis of molecularly targeted agents for treatment of metastatic oesophago-gastric cancer in elderly patients.

Arch Med Sci 2020 2;16(2):253-259. Epub 2020 Mar 2.

Department of Oncology, Tianjin Medical University General Hospital, Tianjin, China.

Introduction: The aim of the present study was to assess the efficacy of molecularly targeted agents (MTAs) in the treatment of elderly patients with metastatic oesophago-gastric cancer (mOGC).

Material And Methods: We systematically searched electronic databases and abstracts presented at American Society of Clinical Oncology (ASCO) meetings up to January 31, 2017. Hazard ratios (HRs) were used to estimate overall survival (OS) and progression-free survival (PFS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.93341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069423PMC

Clinical characteristics and outcomes of patients with overlapping Miller Fisher syndrome and myasthenia gravis.

Arch Med Sci 2020 31;16(1):233-236. Epub 2019 Dec 31.

Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang District, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.91294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963134PMC
December 2019

Some clarifications of terminology may facilitate sarcopenia assessment.

Arch Med Sci 2020 31;16(1):225-232. Epub 2019 Dec 31.

Department of Geriatrics, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.91293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963130PMC
December 2019

The effects of hyperbilirubinaemia on synaptic plasticity in the dentate gyrus region of the rat hippocampus .

Arch Med Sci 2020 14;16(1):200-204. Epub 2019 Oct 14.

Department of Paediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Introduction: The aim of our study is to investigate the effect of hyperbilirubinaemia on synaptic plasticity in the dentate gyrus (DG) region of the rat hippocampus.

Material And Methods: Seven-day-old healthy Sprague Dawley (SD) rats were randomly divided into a control group and an experiment group ( = 20 in each group). The input/output (I/O) functions, paired-pulse reactions (PPR), excitatory postsynaptic potential (EPSP), and population spike (PS) amplitude were measured in the DG area of both groups of rats in response to stimulation applied to the lateral perforant path. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.88625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963152PMC
October 2019
1.890 Impact Factor

Effects of immunisation against PCSK9 in mice bearing melanoma.

Arch Med Sci 2020 31;16(1):189-199. Epub 2019 Dec 31.

Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: Inhibition of proprotein convertase subtilisin/kexin 9 (PCSK9) is an established modality for the treatment of hypercholesterolaemia. However, the impact of PCSK9 inhibition in other situations such as cancer remains largely unknown. The current study was conducted to study the effects of PCSK9 inhibition on cancer endpoints in mice bearing melanoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.91291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963136PMC
December 2019
1.890 Impact Factor

Aberrant expression of long non-coding RNAs (lncRNAs) is involved in brain glioma development.

Arch Med Sci 2020 31;16(1):177-188. Epub 2019 Dec 31.

Department of Neurosurgery, Children's Hospital of Nanjing Medical University, Nanjing, China.

Introduction: Aberrant expression of long non-coding RNAs (lncRNAs) has been implicated in various diseases, including cancer. However, little is known about lncRNAs in human brain gliomas.

Material And Methods: We examined lncRNA profiles from three glioma specimens using lncRNA expression profiling microarrays. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2020.91290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963149PMC
December 2019

MiR-135b-5p promotes viability, proliferation, migration and invasion of gastric cancer cells by targeting Krüppel-like factor 4 (KLF4).

Arch Med Sci 2020 9;16(1):167-176. Epub 2019 Sep 9.

Department of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.

Introduction: The expression of MiR-135b-5p was up-regulated while Krüppel-like factor 4 (KLF4) expression was extremely low in human gastric carcinoma (GC) tissues. This study aimed to explore the role of miR-135b-5p in GC cells and its influence on various cell capacity and viability by targeting KLF4.

Material And Methods: The dual-luciferase reporter assay was first performed and the target relationship between miR-135b-5p and KLF4 was confirmed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.87761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963155PMC
September 2019

Hepatitis B virus screening in patients with non-Hodgkin lymphoma in clinical practice in Poland - a report of the Polish Lymphoma Research Group.

Arch Med Sci 2020 18;16(1):157-161. Epub 2019 Jul 18.

Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.

Introduction: The risk of HBV reactivation is important in lymphoma patients receiving immunosuppressive chemotherapy containing steroids or anti-CD20 antibodies. We aimed to establish the prevalence of HBV Ag and anti-HBc serologic positive results in patients with non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL) in Poland before anti-CD20 therapy initiation; to assess the frequency of insufficient HBV screening; and to assess the association between inadequate HBV screening and diagnosis according to the WHO classification and age or gender.

Material And Methods: We retrospectively collected data from 805 patients with non-Hodgkin lymphoma and chronic lymphocytic leukemia treated in 2016-2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.86761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963131PMC

Breast cancer mortality trends in Europe among women in perimenopausal and postmenopausal age (45+).

Arch Med Sci 2020 11;16(1):146-156. Epub 2019 Jul 11.

Department of Epidemiology and Cancer Prevention, Maria Sklodowska-Curie Institute - Oncology Center, Warsaw, Poland.

Introduction: The aim of the study was to analyze breast cancer (BC) mortality trends among women at the age of 45 years old and older (45+) in the 28 European Union (EU) countries, as well as in 3 non-EU countries - Norway, Switzerland and the Russian Federation (control group) within the period 1959-2017.

Material And Methods: Mortality and population data were sourced from the World Health Organization (WHO) database, and age-standardized mortality rates were calculated using the standard world population. Changes in mortality trends were analyzed using Joinpoint Trend Analysis Software. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.85198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963145PMC

Association of burnout syndrome and global self-esteem among Polish nurses.

Arch Med Sci 2020 14;16(1):135-145. Epub 2019 Oct 14.

Department of Gynecology and Obstetrics, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.

Introduction: The development of burnout syndrome is conditioned by demographic variables, personality-related variables, ways of coping with difficulties and organizational/professional factors. Burnout is a psychological syndrome of emotional exhaustion and fatigue that may occur in people working with other people in certain ways. Understanding the role of global self-esteem and sociodemographic and work environment-related variables in the development of burnout syndrome in Polish nurses was the aim of this study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/aoms.2019.88626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963150PMC
October 2019