7,225 results match your criteria Archives of gynecology and obstetrics[Journal]


Metabolic changes in follicular fluids of patients treated with recombinant versus urinary human chorionic gonadotropin for triggering ovulation in assisted reproductive technologies: a metabolomics pilot study.

Arch Gynecol Obstet 2020 May 27. Epub 2020 May 27.

Department of Sciences, University of Basilicata, viale Ateneo Lucano 10, 85100, Potenza, Italy.

Introduction: The main goal of this retrospective cohort study is the assessment of the effects of administration of recombinant-hCG (r-hCG) versus urinary-hCG (u-hCG) on follicular fluid (FF) composition of women who underwent in vitro fertilization (IVF) treatments.

Materials And Methods: We selected 70 patients with infertility attributable to tubal diseases, unexplained infertility, and male factor. Metabolomics analysis of their FFs was performed by H nuclear magnetic resonance (H NMR) spectroscopy in combination with multivariate analysis to interpret the spectral data. Read More

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http://dx.doi.org/10.1007/s00404-020-05609-zDOI Listing

A 10-year retrospective cohort study to assess objective and subjective outcomes of combined stapled transanal rectal resection and urogynecological surgery for pelvic floor dysfunction.

Arch Gynecol Obstet 2020 May 26. Epub 2020 May 26.

Department of Obstetrics, Gynecology and Urogynecology, Santa Maria Dei Battuti Hospital, Conegliano, Treviso, Italy.

Purpose: To assess the subjective and objective outcomes of combined stapled transanal rectal resection (STARR) and urogynecological surgery to treat pelvic organ prolapse, with a 10-year follow-up.

Methods: This was a retrospective cohort study analyzing prospectively collected data from 53 consecutive patients who underwent combined stapled transanal rectal resection and urogynecological surgery, from 1 January 2005 to 31 December 2007 at a tertiary referral Pelvic Floor Unit of an Italian hospital.

Results: Fifty-three patients with a median age of 60 years (interquartile range (IQR) 67-52t), underwent STARR and concomitant urogynecological surgery. Read More

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http://dx.doi.org/10.1007/s00404-020-05605-3DOI Listing

Social support, self-efficacy, cognitive coping and psychological distress in infertile women.

Arch Gynecol Obstet 2020 May 26. Epub 2020 May 26.

Centre for Clinical Psychology, University of the Punjab, New Campus, Lahore, Pakistan.

Purpose: The aims of this research were to investigate the relationship of social support, self-efficacy and cognitive coping with psychological distress, as well as, to determine the mediating role of self-efficacy and cognitive coping between social support and psychological distress in infertile women of Pakistan.

Methods: This cross-sectional study was conducted to recruit 158 infertile women from six hospitals of Lahore, Pakistan. A demographic questionnaire, multidimensional scale of perceived social support, infertility self-efficacy scale, coping strategies questionnaire and depression anxiety stress scale were used to assess the study variables. Read More

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http://dx.doi.org/10.1007/s00404-020-05614-2DOI Listing

The work and training situation for young physicians undergoing specialty training in gynecology and obstetrics in Germany: an assessment of the status quo.

Arch Gynecol Obstet 2020 May 26. Epub 2020 May 26.

Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.

Purpose: General conditions in the health-care system in Germany have changed dramatically in recent years. Factors affecting this include above all demographic change, rapid developments in diagnostic and therapeutic options, and the application of economic criteria to the health-care sector. This study aimed to establish the current status quo regarding conditions of work and training for young doctors in gynecology and obstetrics, analyze stress factors, and suggest potential improvements. Read More

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http://dx.doi.org/10.1007/s00404-020-05616-0DOI Listing

The effect of the implementation of institutional checklist on expert opinion of oxytocin use in labor.

Arch Gynecol Obstet 2020 May 25. Epub 2020 May 25.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.

Purpose: Oxytocin is a commonly used drug in the labor and delivery unit. There are wide variations in oxytocin use between countries and medical centers, which may reflect the lack of structured guidelines. The aim of our study was to evaluate the need of oxytocin checklist in labor and delivery unit, while assessing the management of oxytocin with and without such a checklist. Read More

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http://dx.doi.org/10.1007/s00404-020-05590-7DOI Listing

Ovarian stimulation after dehydroepiandrosterone supplementation in poor ovarian reserve: a randomized clinical trial.

Arch Gynecol Obstet 2020 May 25. Epub 2020 May 25.

Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University, Round Road, Ismailia, 41111, Egypt.

Objective: This study aimed at improving fertility rates among infertile women with poor ovarian reserve.

Methods: This was a randomized clinical trial conducted in the outpatient clinic of a tertiary hospital. We recruited infertile women with poor ovarian reserve. Read More

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http://dx.doi.org/10.1007/s00404-020-05603-5DOI Listing

Early sonographic evaluation of the placenta in cases with IUGR: a pilot study.

Arch Gynecol Obstet 2020 May 25. Epub 2020 May 25.

Department of Obstetrics and Prenatal Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.

Purpose: The objective of this study was to evaluate the feasibility and value of measuring early placental echogenicity to predict fetal intrauterine growth restriction (IUGR).

Methods: This is a single center, retrospective cohort study. Early ultrasound examination (6 + o to 8 + 6 weeks of gestation in singleton pregnancies) was used to measure placental dimensions and placental echogenicity. Read More

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http://dx.doi.org/10.1007/s00404-020-05601-7DOI Listing

Association between transthyretin concentrations and gestational diabetes mellitus in Chinese women.

Arch Gynecol Obstet 2020 May 25. Epub 2020 May 25.

Obstetrical Department, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang Province, China.

Background: Transthyretin (TTR) is considered to be associated with insulin resistance in humans. This study aimed to investigate TTR level in gestational diabetes mellitus (GDM) and its association with glucose metabolism.

Methods: Fifty pregnant women with GDM and 47 pregnant women with normal glucose tolerance matched for body mass index and age were enrolled in this study. Read More

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http://dx.doi.org/10.1007/s00404-020-05599-yDOI Listing

Prevalence of levator ani avulsion in a multicenter study (PAMELA study).

Arch Gynecol Obstet 2020 May 24. Epub 2020 May 24.

Sant Pau Biomedical Research Institute (IIB Sant Pau) and CIBER Epidemiology and Public Health (CIBERESP), Barcelona, Spain.

Purpose: The objective is to determine the prevalence of levator ani muscle (LAM) avulsion using four-dimensional ultrasound in primiparous women after vaginal delivery and according to delivery mode.

Methods: This prospective, multicenter study included 322 women evaluated at 6-12 months postpartum by four-dimensional transperineal ultrasound to identify levator ani muscle avulsion. The researcher who performed the ultrasound was blinded to all clinical data. Read More

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http://dx.doi.org/10.1007/s00404-020-05585-4DOI Listing

Vesicoamniotic shunting for fetal megacystis in the first trimester with a Somatex intrauterine shunt.

Arch Gynecol Obstet 2020 May 24. Epub 2020 May 24.

Department of Obstetrics and Prenatal Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.

Purpose: The objective was to evaluate the feasibility of vesicoamniotic shunting (VAS) in the first trimester with the Somatex intrauterine shunt and report on complications and neonatal outcome.

Methods: Retrospective cohort study of all VAS before 14 weeks at two tertiary fetal medicine centres from 2015 to 2018 using a Somatex intrauterine shunt. All patients with a first trimester diagnosis of megacystis in male fetuses with a longitudinal bladder diameter of at least 15 mm were offered VAS. Read More

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http://dx.doi.org/10.1007/s00404-020-05598-zDOI Listing

Therapy of pessary-induced rectovaginal fistula and pelvic organ prolapse in elderly patients by vaginal approach and modified LeFort colpocleisis: a case series.

Arch Gynecol Obstet 2020 May 24. Epub 2020 May 24.

Department of Obstetrics and Gynecology, University Hospital Tuebingen, Calwerstrasse 7, 72076, Tübingen, Germany.

Purpose: Pelvic organ prolapse (POP) presents a common benign condition in women associated with reduced quality of life (QoL). The use of pessaries is considered a first-line treatment of POP. However, pessaries can cause perforations into adjacent organs resulting in fistulas. Read More

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http://dx.doi.org/10.1007/s00404-020-05602-6DOI Listing

Intraoperative indocyanine green fluorescence imaging in breast surgery.

Arch Gynecol Obstet 2020 May 23. Epub 2020 May 23.

Department of Gynecology, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

Background: Since postoperative complications after reconstructive breast surgery are often related to drastic increases of patient suffering and treatment costs, several devices were developed in order to avoid them. In this respect, the intraoperative fluorescence angiography with indocyanine green (ICG) provides promising results by detecting ischemic skin intraoperatively.

Methods: Women who underwent reconstructive breast surgery at the breast center at Charité between April and December 2017 were included in the analysis. Read More

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http://dx.doi.org/10.1007/s00404-020-05582-7DOI Listing

Improvement in quality of life and pain scores after laparoscopic management of deep endometriosis: a retrospective cohort study.

Arch Gynecol Obstet 2020 May 23. Epub 2020 May 23.

Endometriosis Center, Acibadem Fulya Hospital, Istanbul, Turkey.

Purpose: This is a retrospective cohort study that evaluates the postoperative pain findings of a consecutive series of laparoscopic surgeries for deep endometriosis (DE).

Methods: This multi-center retrospective cohort study was carried out in university hospitals (Istanbul, Turkey). Sixty-five patients diagnosed through bimanual gynecologic examination, gynecologic ultrasound or magnetic resonance imaging-confirmed endometrioma and DE together; who underwent a laparoscopic surgery between 2013 and 2019 by a team of gynecologists, colorectal surgeons, and a urologist were retrospectively evaluated. Read More

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http://dx.doi.org/10.1007/s00404-020-05583-6DOI Listing

Neonatal outcomes in singleton pregnancies conceived by fresh or frozen embryo transfer compared to spontaneous conceptions: a systematic review and meta-analysis.

Arch Gynecol Obstet 2020 May 22. Epub 2020 May 22.

Department of Obstetrics and Gynecology, Kingston General Hospital, Queen's University, Kingston, ON, K7L 2V7, Canada.

Purpose: The use of assisted reproductive technology (ART) has increased in the last 2 decades and continuous surveillance is needed. This systematic review aims to assess the risk of adverse neonatal outcomes (preterm birth [PTB], low birth weight [LBW], small-for-gestationalage [SGA] and large for gestational-age [LGA]), in singleton pregnancies conceived by fresh or frozen embryo transfer (FET) compared to spontaneous conceptions.

Methods: Cohort studies were identified from MEDLINE, Embase, Cochrane Library (January 2019), and manual search. Read More

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http://dx.doi.org/10.1007/s00404-020-05593-4DOI Listing

Palliative treatment for bowel obstruction in ovarian cancer: a meta-analysis.

Arch Gynecol Obstet 2020 May 22. Epub 2020 May 22.

Department of Obstetrics and Gynecology, First Affiliated Hospital of Soochow University, 899 Pinghai Road, SuzhouSuzhou, 215006, Jiangsu, China.

Objective: To comprehensively evaluate and compare outcomes of surgical versus nonsurgical palliative interventions for bowel obstruction due to ovarian cancer.

Methods: Studies were obtained from database search systems of Pubmed, Medline, Wiley, Springerlink, Kluwer, Web of science and Science direct. Data were analyzed by the meta-analysis method and the random-effect or fixed-effect model. Read More

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http://dx.doi.org/10.1007/s00404-020-05545-yDOI Listing

Predictors of response after a second attempt of pharmacological labor induction: a retrospective study.

Arch Gynecol Obstet 2020 May 22. Epub 2020 May 22.

Obstetrics and Gynaecology Unit, Mauriziano Umberto I Hospital, Largo Turati 62, 10128, Turin, Italy.

Purpose: The aim of our study was to assess the outcomes of a prolonged induction carried out with a second sequential cycle of pharmacological stimulation after unsatisfactory response to a first attempt, and to highlight variables correlated with higher response rates.

Methods: A retrospective study was carried out on 157 women who underwent a two-step labor induction by vaginal prostaglandins followed by a second cycle of prostaglandins or intravenous oxytocin. Outcomes assessed were mode of delivery and maternal and neonatal morbidity. Read More

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http://dx.doi.org/10.1007/s00404-020-05578-3DOI Listing

Takayasu arteritis and pregnancy.

Authors:
Johann Auer

Arch Gynecol Obstet 2020 May 21. Epub 2020 May 21.

Department of Cardiology and Intensive Care, St. Josef Hospital Braunau, Ringstrasse 60, 5280, Braunau, Austria.

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http://dx.doi.org/10.1007/s00404-020-05594-3DOI Listing

High PD-1 expression level is associated with an unfavorable prognosis in patients with cervical adenocarcinoma.

Arch Gynecol Obstet 2020 May 20. Epub 2020 May 20.

Department of Obstetrics and Gynecology, Shimane University Faculty of Medicine, Enyacho 89-1, Izumo, Shimane, 6938501, Japan.

Purpose: The effectiveness of immunotherapy for cervical adenocarcinoma (CA) has not been demonstrated yet. Programmed cell death 1 (PD-1), programmed cell death-ligand 1 (PD-L1), and CD8 may be used as biomarkers of response to immune therapy in CA patients. In the present study, we aimed to investigate whether the expression levels of PD-1, PD-L1, and CD8 can predict the prognosis of patients with CA and their response to immune checkpoint inhibition therapy. Read More

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http://dx.doi.org/10.1007/s00404-020-05589-0DOI Listing

Retrospective analysis of clinicopathological features and prognosis for aggressive angiomyxoma of 27 cases in a tertiary center: a 14-year survey and related literature review.

Arch Gynecol Obstet 2020 May 19. Epub 2020 May 19.

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, 110004, Liaoning, China.

Purpose: Aggressive angiomyxoma (AAM) is a rare and often misdiagnosed tumor that is characterized by frequent local recurrences. This study aimed to investigate the clinicopathological characteristics, surgical experiences, and prognosis for aggressive angiomyxoma to improve the accuracy of diagnosis and develop treatment strategies for decreasing recurrence rates.

Methods: Clinicopathological data and follow-up information for 27 patients with AAM diagnosed and treated at the Shengjing Hospital of China Medical University between January 2006 and October 2019 were retrospectively analyzed. Read More

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http://dx.doi.org/10.1007/s00404-020-05592-5DOI Listing

Quality of life and associated factors after surgical treatment of vulvar cancer by vulvar field resection (VFR).

Arch Gynecol Obstet 2020 May 19. Epub 2020 May 19.

Department of Gynecology, University Hospital Leipzig, Liebigstr. 20a, 04103, Leipzig, Germany.

Purpose: To investigate patient-reported quality of life (QoL) and associated factors in vulvar cancer patients treated surgically by vulvar field resection (VFR) without adjuvant radiation.

Methods: We retrospectively evaluated patient-reported QoL as part of the prospective monocentric VFR trial using the 30-item European Organization for Research and Treatment of Cancer quality-of-life questionnaire (EORTC QLQ-C30) supplemented by a question assessing sexual activity. All patients had been treated by VFR and no participant had received adjuvant radiotherapy. Read More

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http://dx.doi.org/10.1007/s00404-020-05584-5DOI Listing

Ovarian Sertoli-Leydig cell tumors: an analysis of 13 cases.

Arch Gynecol Obstet 2020 May 19. Epub 2020 May 19.

International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Purpose: To report the clinical, ultrasound and histopathological characteristics, clinical management, and prognosis of 13 patients with Sertoli-Leydig cell tumors (SLCTs) of ovary.

Methods: 13 patients with pathologically confirmed ovarian SLCTs at International Peace Maternity and Child Health Hospital from 2010 and 2019 were included in this study. The clinical, ultrasound and histopathological characteristics, clinical management, and prognosis of 13 patients were retrospectively analyzed. Read More

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http://dx.doi.org/10.1007/s00404-020-05588-1DOI Listing

Systematic lymphadenectomy in early stage endometrial cancer.

Arch Gynecol Obstet 2020 May 19. Epub 2020 May 19.

Department of Gynecology and Obstetrics, Klinikum Magdeburg, Magdeburg, Germany.

Background: The positive effect of systematic lymphadenectomy on survival of patients with endometrial cancer is a topic of ongoing debate.

Methods: We aimed to investigate whether systemic lymphadenectomy is beneficial for patients with early endometrial cancer. For this purpose, we analyzed a population-based registry with of 2392 women with endometrioid endometrial cancer, stage I and II at intermediate and high risk of recurrence. Read More

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http://dx.doi.org/10.1007/s00404-020-05600-8DOI Listing

Age at surgery and recurrence of ovarian endometrioma after conservative surgery: a meta-analysis including 3125 patients.

Arch Gynecol Obstet 2020 May 19. Epub 2020 May 19.

Department of Gynecology of Traditional Chinese Medicine, China-Japan Friendship Hospital, Ying Hua Yuan East Street, Chao Yang District, Beijing, China.

Purpose: To evaluate the association between age at surgery and recurrence rate of endometrioma. Data sources PubMed, Embase, and the Cochrane Library were searched up to October 2019.

Methods: We determined the pooled relative risk (RR) and 95% confidence intervals (CIs) to assess the relationship between age at surgery and the recurrence rate of endometrioma after surgery. Read More

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http://dx.doi.org/10.1007/s00404-020-05586-3DOI Listing

Vitamin D status in endometriosis: a systematic review and meta-analysis.

Arch Gynecol Obstet 2020 May 19. Epub 2020 May 19.

Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.

Purpose: No consensus exists on the relationship between vitamin D status and endometriosis. The chief aim of our study was to evaluate the association between serum vitamin D levels and endometriosis.

Methods: We searched for MEDLINE, EMBASE, and China National Knowledge Infrastructure (CNKI) databases for studies elucidated the circulating vitamin D levels in endometriosis. Read More

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http://dx.doi.org/10.1007/s00404-020-05576-5DOI Listing

Comparison of placental elasticity in normal and intrauterine growth retardation pregnancies by ex vivo strain elastography.

Arch Gynecol Obstet 2020 May 19. Epub 2020 May 19.

Perinatology Department, Training and Research Hospital, Etlik Zubeyde Hanim Women's Health Care, Ankara, Turkey.

Objective: To compare the placental elasticity in fetuses with or without intrauterine growth restriction (IUGR).

Materials And Methods: One hundred pregnant women (50 IUGR and 50 healthy) with anteriorly located placenta were evaluated during the third trimester of pregnancy. Measurements were carried out by a machine that has a real-time elastographic ultrasonography feature. Read More

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http://dx.doi.org/10.1007/s00404-020-05596-1DOI Listing

Potential suppressive functions of microRNA-504 in cervical cancer cells malignant process were achieved by targeting PAICS and regulating EMT.

Arch Gynecol Obstet 2020 May 16. Epub 2020 May 16.

Department of Gynecology, Shandong Provincial Hospital Affiliated to Shandong University, No. 324 Jingwu Weiqi Road, Huai-Yin District, Jinan, Shandong, 250021, People's Republic of China.

Purpose: The present study aimed to investigate the effects of miR-504 in cervical cancer.

Methods: Normal and cervical cancer tissue specimens derived from TCGA and GTEx databases were employed to analyze the miR-504 and PAICS (one of potential target gene of miR-504) expression. Kaplan-Meier strategy was applied to analyze the prognostic powers of miR-504 and PAICS. Read More

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http://dx.doi.org/10.1007/s00404-020-05538-xDOI Listing

Effectiveness of functional exercises on pain and sleep quality in patients with primary dysmenorrhea: a randomized clinical trial.

Arch Gynecol Obstet 2020 May 15. Epub 2020 May 15.

Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Eastern Mediterranean University, Famagusta, North Cyprus, via Mersin-10, Turkey.

Purpose: Primary dysmenorrhea is the most common gynecological problem in young women and adolescents. Exercise therapy provides positive effects on women with primary dysmenorrhea. The aim of the study was to investigate the effects of a combined exercise program on pain, sleep and menstrual symptoms in patients with primary dysmenorrhea. Read More

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http://dx.doi.org/10.1007/s00404-020-05579-2DOI Listing

The use of absorbable adhesion barriers to reduce the incidence of intraperitoneal adhesions at repeat cesarean delivery.

Arch Gynecol Obstet 2020 May 15. Epub 2020 May 15.

Department of Obstetrics and Gynecology, 12 Bayit Shaare Zedek Medical Center, Affiliated with the Hebrew University School of Medicine, 91031, Jerusalem, Israel.

Purpose: We aimed to evaluate the effect of an absorbable adhesion barrier (oxidized regenerated cellulose) for the prevention of peritoneal adhesions in women undergoing repeat cesarean delivery (CD).

Methods: This is a retrospective, single center study that included all women who underwent two consecutive CDs, 2011-2018. Women in whom an absorbable adhesion barrier (oxidized regenerated cellulose) was placed at the time of the initial CD (index CD) were compared to women in whom no such barrier was placed. Read More

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http://dx.doi.org/10.1007/s00404-020-05591-6DOI Listing

Induction of labor, and physiological and psychological stress responses as expressed by salivary cortisol: a prospective study.

Arch Gynecol Obstet 2020 May 15. Epub 2020 May 15.

Department of Obstetrics and Gynecology, Meir Medical Center, 59 Tchernichovsky St, Kfar Saba, 4428164, Israel.

Purpose: To describe patterns of physiological and psychological stress during induced labor and their correlation to obstetrical and neonatal outcomes.

Methods: This prospective, observational study included 167 women, with low-risk, singleton pregnancies, who delivered at term, at a tertiary academic center from 2015 through 2018. Among them, 72 (43%) underwent induction and 95 (57%) had spontaneous labor onset. Read More

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http://dx.doi.org/10.1007/s00404-020-05577-4DOI Listing

Does lymph node ratio have any prognostic significance in maximally cytoreduced node-positive low-grade serous ovarian carcinoma?

Arch Gynecol Obstet 2020 May 14. Epub 2020 May 14.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Baskent University, Ankara, Turkey.

Purpose: To determine the prognostic impact of the lymph node ratio (LNR) in node-positive low-grade serous ovarian cancer (LGSOC).

Methods: We retrospectively reviewed women with LGSOC who had undergone maximal cytoreduction followed by standard chemotherapy in 11 centers from Turkey during a study period of 20 years. Sixty two women with node-positive LGSOC were identified. Read More

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http://dx.doi.org/10.1007/s00404-020-05580-9DOI Listing

Prenatal effects of maternal nutritional stress and mental health on the fetal movement profile.

Arch Gynecol Obstet 2020 May 14. Epub 2020 May 14.

Department of Mathematical Sciences, Durham University, South Road, Durham, DH1 3LE, UK.

Purpose: Prenatal sub-optimal nutrition and exposure to maternal stress, anxiety and depression in pregnancy have been linked to increased postnatal morbidity and mortality. Fetal growth is most vulnerable to maternal dietary deficiencies, such as those evident in hyperemesis gravidarum (HG), early in pregnancy. The purpose of this pilot study was to examine the effects of HG on fetal movement profiles as a measure of fetal healthy development in the 3rd trimester of pregnancy, and to assess whether nutritional stress on the mother can be evaluated using isotopic analysis of hair. Read More

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http://dx.doi.org/10.1007/s00404-020-05571-wDOI Listing

A high Glasgow prognostic score (GPS) or modified Glasgow prognostic score (mGPS) predicts poor prognosis in gynecologic cancers: a systematic review and meta-analysis.

Arch Gynecol Obstet 2020 Jun 14;301(6):1543-1551. Epub 2020 May 14.

Department of Gynecology, Affiliated Hospital of Southwest Medical University, No.8 Section 2, Kangcheng Road, Luzhou, Sichuan, 646000, People's Republic of China.

Purpose: The Glasgow Prognostic Score or modified Glasgow Prognostic Score (GPS/mGPS), a novel inflammatory indicator, which acts as a prognostic predictor in various cancers. However, these results are still controversial. In this meta-analysis, we aimed to investigate the prognostic role of GPS/mGPS in patients with gynecologic cancers. Read More

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http://dx.doi.org/10.1007/s00404-020-05581-8DOI Listing

Term cesarean breech delivery in the first pregnancy is associated with an increased risk for maternal and neonatal morbidity in the subsequent delivery: a national cohort study.

Arch Gynecol Obstet 2020 May 14. Epub 2020 May 14.

Department of Obstetrics and Gynecology, University Hospital Marburg, Marburg, Germany.

Purpose: To determine whether there is an association between term cesarean breech delivery in the first pregnancy and maternal and neonatal morbidities in the subsequent pregnancy and delivery.

Methods: We conducted a retrospective, nationwide Finnish population-based cohort study, including all deliveries from January 2000 to December 2017. We included all women with the first two consecutive singleton deliveries of which the first one was a breech delivery regardless of mode of delivery (n = 11,953), and constructed a data set in which the first two deliveries for these women were connected. Read More

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http://dx.doi.org/10.1007/s00404-020-05575-6DOI Listing

Association of antibiotics therapy during pregnancy with spontaneous miscarriage: a systematic review and meta-analysis.

Arch Gynecol Obstet 2020 May 14. Epub 2020 May 14.

Endocrinology Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.

Purpose: This systematic review and meta-analysis of observational studies were conducted to assess the association between antibiotics use during pregnancy and spontaneous miscarriage.

Methods: A systematic search of online databases as well as reference lists of retrieved studies were performed up to September 2018 to identify observational studies that investigated the association between antibiotics use and spontaneous miscarriage. The retrieved studies were assessed for methodological quality. Read More

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http://dx.doi.org/10.1007/s00404-020-05569-4DOI Listing

Effect of prolactin and estrogen on the serum level of 1,25-dihydroxy vitamin D and FGF23 in female rats.

Arch Gynecol Obstet 2020 May 14. Epub 2020 May 14.

Shiraz Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, P.O. Box, 71345-1744, Shiraz, Iran.

Introduction: Estrogen and prolactin affect vitamin D metabolism. In conditions such as pregnancy and lactation, their interaction in regulating vitamin D metabolism and circulating FGF23 is not clearly defined. The aim of this study is to investigate this interaction in female rats. Read More

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http://dx.doi.org/10.1007/s00404-020-05567-6DOI Listing

Reduced incidence of early preterm birth in the State of Thuringia following an intravaginal pH-self-monitoring screening program.

Arch Gynecol Obstet 2020 May 14. Epub 2020 May 14.

Berufsverband der Frauenärzte E.V., Landesvorsitzender Thüringen, 99768, Harztor, Germany.

Background: Effective prevention of preterm birth as cause of serious risks for the infant as well as the mother pre- and postpartum is one of the still unsolved problems in modern medicine.

Method: The government of the State of Thuringia in cooperation with the professional organization of obstetricians and gynecologists decided in 2016 to reestablish and promote a self-care screening program based on intravaginal (i.vag. Read More

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http://dx.doi.org/10.1007/s00404-020-05574-7DOI Listing

Impact of a selective use of episiotomy combined with Couder's maneuver for the perineal protection.

Arch Gynecol Obstet 2020 May 9. Epub 2020 May 9.

Department of Obstetrics and Gynecology, University Hospital Jean Minjoz, University of Franche-Comté, 25000, Besançon, France.

Purpose: To evaluate the impact of a selective use of episiotomy combined with Couder's maneuver on the incidence of perineal tears in spontaneous term deliveries.

Methods: A comparative, retrospective, mono-centric study in a university maternity unit was designed and included all primiparous women who delivered spontaneously after 37 weeks of gestation in cephalic presentation. Two cohorts were studied, before and after the practice of Couder's maneuver. Read More

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http://dx.doi.org/10.1007/s00404-020-05572-9DOI Listing

Comparison of criteria of International Association of Diabetes and Pregnancy Study Groups (IADPSG) with National Institute for Health and Care Excellence (NICE) for diagnosis of gestational diabetes mellitus.

Arch Gynecol Obstet 2020 May 9. Epub 2020 May 9.

Department of Endocrinology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Background: Different screening procedures and diagnostic criteria are being followed in the same as well as in different countries with no single standard criteria established for diagnosis of GDM. So far, there are no studies in the Indian population comparing IADPSG with NICE criteria.

Objective: To compare International Association of Pregnancy and Study Groups (IADPSG) criteria with the National Institute for Health and Care Excellence (NICE) for diagnosis of gestational diabetes mellitus and its influence on maternal and perinatal outcomes. Read More

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http://dx.doi.org/10.1007/s00404-020-05564-9DOI Listing

Motherhood after cancer: fertility and utilisation of fertility-preservation methods.

Arch Gynecol Obstet 2020 Jun 6;301(6):1579-1588. Epub 2020 May 6.

Department for Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Heidelberg, Heidelberg, Germany.

Purpose: Due to modern and individualised treatments, women at reproductive age have a high survival rate after cancer therapy. What are pregnancy and birth rates of women after cancer and how often do they use cryopreserved ovarian tissue or gametes?

Methods: From 2007 to 2015, 162 women aged 26.7 ± 6. Read More

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http://dx.doi.org/10.1007/s00404-020-05563-wDOI Listing

Disease flare at prior pregnancy and disease activity at conception are important determinants of disease relapse at subsequent pregnancy in women with inflammatory bowel diseases.

Arch Gynecol Obstet 2020 Jun 6;301(6):1449-1454. Epub 2020 May 6.

IBD MOM Unit, Shaare Zedek Medical Center, Digestive Diseases Institute, Affiliated with the Medical School Hebrew University, Jerusalem, Israel.

Purpose: Disease flare throughout gestation are not uncommon among women with inflammatory bowel diseases (IBD), and can substantially affect pregnancy outcomes. We aimed to evaluate the effect of prior pregnancy outcome on the risk of disease flare at subsequent pregnancy in women with IBD.

Methods: Women with IBD attending a multidisciplinary clinic for the preconception, antenatal and postnatal treatment were prospectively recruited during 2011-2018. Read More

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http://dx.doi.org/10.1007/s00404-020-05557-8DOI Listing

Reduction in physical activity significantly increases depression and anxiety in the perinatal period: a longitudinal study based on a self-report digital assessment tool.

Arch Gynecol Obstet 2020 May 5. Epub 2020 May 5.

Department of Obstetrics and Gynecology, University of Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany.

Purpose: Physical activity can reduce pregnancy-related complications and contributes substantially to improving maternal mental health. A reduction in activity encompassing exercise and daily household tasks throughout the course of pregnancy increases the risk of depression and anxiety. The following research examines the longitudinal interaction between exercise, general physical activity, and mental health outcomes in pregnant women. Read More

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http://dx.doi.org/10.1007/s00404-020-05570-xDOI Listing

Vaginal prolapse with ulceration and intestinal involvement.

Arch Gynecol Obstet 2020 Jun;301(6):1353-1354

Department of Gynaecology and Obstetrics, University Hospital Tuebingen, Calwerstrasse 7, 72076, Tuebingen, Germany.

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http://dx.doi.org/10.1007/s00404-020-05566-7DOI Listing

Plasma pentraxin 3 is higher in early ovarian hyperstimulation syndrome than in uncomplicated in vitro fertilization cycle of high-risk women.

Arch Gynecol Obstet 2020 Jun 5;301(6):1569-1578. Epub 2020 May 5.

Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 2, PO Box 140, 00290, Helsinki, Finland.

Purpose: Pentraxin 3 (PTX3) is a locally secreted, quicker responsive pro-inflammatory protein than C-reactive protein (CRP). We evaluated the value of PTX3 in the prediction of ovarian hyperstimulation syndrome (OHSS), a severe complication of in vitro fertilization (IVF).

Methods: This two-year prospective follow-up study included 27 women with uncomplicated IVF-cycles (IVF group) and 31 patients diagnosed with moderate or severe early OHSS (OHSS group). Read More

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http://dx.doi.org/10.1007/s00404-020-05556-9DOI Listing

Does timing in ICSI cycle affect oocyte quality and reproductive outcomes? A prospective study.

Arch Gynecol Obstet 2020 May 4. Epub 2020 May 4.

Men's Health and Reproductive Health Research Center (MHRHRC), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To evaluate the association of time intervals between various steps of the intracytoplasmic sperm injection (ICSI) cycle with oocyte quality and reproductive outcomes.

Methods: We conducted a prospective study among patients undergoing ICSI cycles in an academic hospital between May 2017 and January 2019. The time intervals between the various steps of cycles were recorded. Read More

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http://dx.doi.org/10.1007/s00404-020-05555-wDOI Listing

Complement and other immune-related factors in cervicovaginal fluid associated with intra-amniotic infection/inflammation and spontaneous preterm delivery in women with preterm labor.

Arch Gynecol Obstet 2020 Jun 4;301(6):1431-1439. Epub 2020 May 4.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

Purpose: To investigate whether complement and other immune-related proteins in cervicovaginal fluid (CVF) can predict intra-amniotic infection and/or inflammation (IAI) and spontaneous preterm delivery (SPTD, < 34.0 weeks) in women with preterm labor (PTL) and to compare the predictive abilities of these biomarkers with that of amniotic fluid (AF) white blood cells (WBCs).

Methods: We designed a retrospective cohort study of 145 women with PTL at 23. Read More

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http://dx.doi.org/10.1007/s00404-020-05560-zDOI Listing

Is advanced maternal age associated with placental vascular malperfusion? A prospective study from a single tertiary center.

Arch Gynecol Obstet 2020 Jun 3;301(6):1441-1447. Epub 2020 May 3.

Departments of Obstetrics and Gynecology, The Edith Wolfson Medical Center, P.O Box 5, 58100, Holon, Israel.

Purpose: Pregnancy at advanced maternal age (AMA) has become more common. There has been concern regarding the adverse effect deferring pregnancy might have on pregnancy outcomes. We aimed to prospectively study the effect of AMA on placental pathology. Read More

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http://dx.doi.org/10.1007/s00404-020-05562-xDOI Listing

The role of fetal head circumference in the formation of obstetric anal sphincter injuries following vacuum deliveries among primiparous women.

Arch Gynecol Obstet 2020 Jun 3;301(6):1423-1429. Epub 2020 May 3.

The Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, POB 12000, Jerusalem, Israel.

Purpose: To evaluate the association of sonographic fetal head circumference (HC) with obstetric anal sphincter injury (OASIS) occurrence among primiparous women who underwent vacuum-assisted delivery (VAD).

Methods: A retrospective study of all primiparous women who delivered at term by VAD between 2011 and 2019 and underwent ultrasound with fetal biometry within 1 week prior to delivery. Women who suffered OASIS were compared to women without OASIS. Read More

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http://dx.doi.org/10.1007/s00404-020-05558-7DOI Listing

Use of extracorporeal membrane oxygenation in obstetric patients: a retrospective cohort study.

Arch Gynecol Obstet 2020 Jun 3;301(6):1377-1382. Epub 2020 May 3.

Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, 3755 Chemin de la Côte-Sainte-Catherine, Montreal, QC, H3T 1E2, Canada.

Purpose: There is little information on the use of extracorporeal membrane oxygenation (ECMO) in pregnant women. Our objectives are to estimate the use of ECMO in pregnant patients, identify clinical conditions associated with ECMO use, and assess survival rates by the associated condition.

Methods: Using the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample, we carried out a retrospective cohort study of all delivery admissions in the United States from January 1, 1999, to October 1, 2015. Read More

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http://dx.doi.org/10.1007/s00404-020-05530-5DOI Listing

COX-2-PGE-EPs in gynecological cancers.

Arch Gynecol Obstet 2020 Jun 3;301(6):1365-1375. Epub 2020 May 3.

Department of Obstetrics and Gynecology, Ludwig-Maximilians University of Munich, Campus Großhadern: Marchioninistraße 15, 81377, Munich, Germany.

Purpose: Nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors (COXibs) inhibit the progression of endometrial cancer, ovarian cancer and cervical cancer. However, concerning the adverse effects of NSAIDs and COXibs, it is still urgent and necessary to explore novel and specific anti-inflammation targets for potential chemoprevention. The signaling of cyclooxygenase 2-prostaglandin E-prostaglandin E receptors (COX-2-PGE-EPs) is the central inflammatory pathway involved in the gynecological carcinogenesis. Read More

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http://dx.doi.org/10.1007/s00404-020-05559-6DOI Listing

Comparison of radial and meander-like breast ultrasound with respect to diagnostic accuracy and examination time.

Arch Gynecol Obstet 2020 Jun 3;301(6):1533-1541. Epub 2020 May 3.

Gynecology/Gynecologic Oncology, St.Claraspital Basel, Kleinriehenstrasse 30, 4002, Basel, Switzerland.

Purpose: To prospectively compare the diagnostic accuracy of radial breast ultrasound (r-US) to that of conventional meander-like breast ultrasound (m-US), patients of a consecutive, unselected, mixed collective were examined by both scanning methods.

Methods: Out of 1948 dual examinations, 150 revealed suspicious lesions resulting in 168 biopsies taken from 148 patients. Histology confirmed breast cancers in 36 cases. Read More

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http://dx.doi.org/10.1007/s00404-020-05554-xDOI Listing