3,547 results match your criteria Archives of disease in childhood. Fetal and neonatal edition[Journal]


Consensus outcome rating for international neonatal resuscitation guidelines.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 29. Epub 2019 Mar 29.

Pediatrics-Neonatal, University of Michigan Hospital, Ann Arbor, Michigan, USA.

The International Liaison Committee on Resuscitation uses the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) working group method to evaluate the quality of evidence and the strength of treatment recommendations. This method requires guideline developers to use a numerical rating of the importance of each specified outcome. There are currently no uniform reporting guidelines or outcome measures for neonatal resuscitation science. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2019-31694
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http://dx.doi.org/10.1136/archdischild-2019-316942DOI Listing
March 2019
3 Reads
3.120 Impact Factor

Group B streptococcal sepsis and congenital diaphragmatic hernia: do not overlook normal initial imaging studies!

Arch Dis Child Fetal Neonatal Ed 2019 Mar 29. Epub 2019 Mar 29.

Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/archdischild-2018-316667DOI Listing
March 2019
1 Read

Neonatal outcomes in preterm multiples receiving delayed cord clamping.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 20. Epub 2019 Mar 20.

Department of Pediatrics, Newborn Medicine, Santa Clara Valley Medical Center, San Jose, California, USA.

Objective: To compare neonatal outcomes in singletons versus multiples, first-born versus second-born multiples and monochorionic versus dichorionic/trichorionic multiples <33 weeks' gestational age (GA) who received delayed cord clamping (DCC).

Design: Retrospective, observational study of 529 preterm infants receiving ≥30 s DCC. Generalised estimating equations and mixed effects models were used to compare outcomes in singletons versus multiples and monochorionic versus dichorionic/trichorionic multiples. Read More

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http://dx.doi.org/10.1136/archdischild-2018-316479DOI Listing
March 2019
3.120 Impact Factor

Duration of mechanical ventilation and neurodevelopment in preterm infants.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 20. Epub 2019 Mar 20.

Neonatology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Objective: To investigate the association between invasive mechanical ventilation (IMV) duration and long-term neurodevelopmental outcomes in preterm infants in an era of restricted IMV.

Design: Retrospective cohort study.

Setting: Single neonatal intensive care unit in Amsterdam. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315993DOI Listing
March 2019
1 Read

Assessing the deprivation gap in stillbirths and neonatal deaths by cause of death: a national population-based study.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 6. Epub 2019 Mar 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

Objective: To investigate socioeconomic inequalities in cause-specific stillbirth and neonatal mortality to identify key areas of focus for future intervention strategies to achieve government ambitions to reduce mortality rates.

Design: Retrospective cohort study.

Setting: England, Wales, Scotland and the UK Crown Dependencies. Read More

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http://dx.doi.org/10.1136/archdischild-2018-316124DOI Listing
March 2019
1 Read

Tactile stimulation in the delivery room: do we practice what we preach?

Arch Dis Child Fetal Neonatal Ed 2019 Mar 1. Epub 2019 Mar 1.

Department of Paediatrics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316344DOI Listing

Compromised pressure and flow during suction mask ventilation.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 1. Epub 2019 Mar 1.

Newborn Research Centre and Neonatal Services, The Royal Women's Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1136/archdischild-2018-316366DOI Listing

Exome sequencing in the assessment of congenital malformations in the fetus and neonate.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 1. Epub 2019 Feb 1.

West Midlands Fetal Medicine Centre, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.

Major congenital anomalies are often associated with perinatal mortality, long-term morbidity and prolonged hospitalisation. Prenatal ultrasound remains the principle diagnostic test for many anomalies, but despite this up to one-third are only identified in the neonatal period. The primary step in determining underlying aetiology is to define accurately the phenotype by recognition of dysmorphology (both prenatally and postnatally). Read More

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http://dx.doi.org/10.1136/archdischild-2018-316352DOI Listing
February 2019

Intubation difficulty in neonatology: are you experienced?

Arch Dis Child Fetal Neonatal Ed 2019 Feb 22. Epub 2019 Feb 22.

School of Medicine, University College Dublin, Dublin, Ireland.

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31671
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http://dx.doi.org/10.1136/archdischild-2018-316711DOI Listing
February 2019
4 Reads

Automated oxygen control in the preterm infant: automation yes, but we need intelligence.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 22. Epub 2019 Feb 22.

School of Engineering and ICT, University of Tasmania, Hobart, Tasmania, Australia.

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http://dx.doi.org/10.1136/archdischild-2018-316371DOI Listing
February 2019

Incidence, impact and indicators of difficult intubations in the neonatal intensive care unit: a report from the National Emergency Airway Registry for Neonates.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 22. Epub 2019 Feb 22.

Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Objective: To determine the incidence, indicators and clinical impact of difficult tracheal intubations in the neonatal intensive care unit (NICU).

Design: Retrospective review of prospectively collected data on intubations performed in the NICU from the National Emergency Airway Registry for Neonates.

Setting: Ten academic NICUs. Read More

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http://dx.doi.org/10.1136/archdischild-2018-316336DOI Listing
February 2019
1 Read
3.120 Impact Factor

Cardiac arrest with pulseless electrical activity rhythm in newborn infants: a case series.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 22. Epub 2019 Feb 22.

Department of Neonatology, Royal Alexandra Hospital, Edmonoton, Alberta, Canada.

The 2015 neonatal resuscitation guidelines added ECG to assess an infant's heart rate when determining the need for resuscitation at birth. However, a recent case report raised concerns about this technique in the delivery room. We report four cases of pulseless electrical activity during neonatal cardiopulmonary resuscitation in levels II-III neonatal intensive care units in Canada (Edmonton [n=3] and Winnipeg [n=1]). Read More

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http://dx.doi.org/10.1136/archdischild-2018-316087DOI Listing
February 2019
2 Reads

White chalky dermatitis in a very preterm neonate with fungal skin infection.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 22. Epub 2019 Feb 22.

Division of Neonatology, Tokyo Metroplitan Children's Medical Center, Fuchu, Tokyo, Japan.

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http://dx.doi.org/10.1136/archdischild-2018-316451DOI Listing
February 2019
1 Read

Validation of the disposable T-piece resuscitator (Neo-Tee): a bench study.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 19. Epub 2019 Feb 19.

Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Objective: The Neo-Tee Infant T-piece resuscitator is a disposable T-piece resuscitator. The aim of this bench study was to assess the accuracy of the Neo-Tee using a measurement set-up and settings mimicking clinical practice.

Study Design: Nine Neo-Tee devices were tested using a face mask interface and a manikin. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315298DOI Listing
February 2019
8 Reads

UK survey of less invasive surfactant administration.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 11. Epub 2019 Feb 11.

Department of Women and Children's Health, School of Life Sciences, Faculty of Life Science and Medicine, King's College London, London, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316466DOI Listing
February 2019
4 Reads

Current clinical practice in neonatologist-performed echocardiography in the UK.

Authors:
Yogen Singh

Arch Dis Child Fetal Neonatal Ed 2019 Feb 8. Epub 2019 Feb 8.

Neonatology/Paediatric Cardiology, Addenbrooke's, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316348DOI Listing
February 2019
1 Read

Neonatal cardiopulmonary transition in an ovine model of congenital diaphragmatic hernia.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 6. Epub 2019 Feb 6.

The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria, Australia.

Objective: Infants with a congenital diaphragmatic hernia (CDH) are at high risk of developing pulmonary hypertension after birth, but little is known of their physiological transition at birth. We aimed to characterise the changes in cardiopulmonary physiology during the neonatal transition in an ovine model of CDH.

Methods: A diaphragmatic hernia (DH) was surgically created at 80 days of gestational age (dGA) in 10 fetuses, whereas controls underwent sham surgery (n=6). Read More

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http://dx.doi.org/10.1136/archdischild-2018-316045DOI Listing
February 2019
3 Reads

New short-term heat inactivation method of cytomegalovirus (CMV) in breast milk: impact on CMV inactivation, CMV antibodies and enzyme activities.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 6. Epub 2019 Feb 6.

Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital of Tuebingen, Tubingen, Germany.

Objectives: Breast milk (BM) is the primary source of cytomegalovirus (CMV) transmission to premature infants with potentially harmful consequences. We therefore wanted to evaluate temperature and duration of short-term BM pasteurisation with respect to CMV inactivation, effect on CMV-IgG antibodies and BM enzyme activities.

Methods: 116 artificially CMV-spiked BM and 15 wild-type virus-infected samples were subjected for 5 s to different temperatures (55°C-72°C). Read More

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http://dx.doi.org/10.1136/archdischild-2018-316117DOI Listing
February 2019
1 Read

Effects of tracheal occlusion on the neonatal cardiopulmonary transition in an ovine model of diaphragmatic hernia.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 6. Epub 2019 Feb 6.

The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria, Australia.

Objective: Fetoscopic endoluminal tracheal occlusion (FETO) aims to reverse pulmonary hypoplasia associated with congenital diaphragmatic hernia (CDH) and mitigate the associated respiratory insufficiency and pulmonary hypertension after birth. We aimed to determine whether FETO improves the cardiopulmonary transition at birth in an ovine model of CDH.

Methods: In 12 ovine fetuses with surgically induced diaphragmatic hernia (DH; 80 dGA), an endotracheal balloon was placed tracheoscopically at ≈110 dGA and removed at ≈131 dGA (DH+FETO), while 10 were left untreated (DH). Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31604
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http://dx.doi.org/10.1136/archdischild-2018-316047DOI Listing
February 2019
9 Reads

Can we estimate the length of stay of very preterm multiples?

Arch Dis Child Fetal Neonatal Ed 2019 Feb 2. Epub 2019 Feb 2.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316321DOI Listing
February 2019

Intrathoracic renal ectopia with congenital diaphragmatic hernia.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13. Epub 2019 Jan 13.

Neonatal Intensive Care Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31619
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http://dx.doi.org/10.1136/archdischild-2018-316195DOI Listing
January 2019
10 Reads

Parental smoking and support in the NICU.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13. Epub 2019 Jan 13.

Norwich Medical School, University of East Anglia, Norwich, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316413DOI Listing
January 2019
1 Read

Perinatal palliative care: a national survey in Italy.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13. Epub 2019 Jan 13.

Neonatal Intensive Care Unit, Department of Woman's and Child's Health, University of Padua, Padua, Italy.

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http://dx.doi.org/10.1136/archdischild-2018-316327DOI Listing
January 2019
1 Read

Respiratory monitors to teach newborn facemask ventilation: a randomised trial.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13. Epub 2019 Jan 13.

Newborn Research Centre, The Royal Women's Hospital, Parkville, Victoria, Australia.

Objective: The International Liaison Committee on Resuscitation has found that there is a need for high-quality randomised trials of training interventions that improve the effectiveness of resuscitation skills. The objective of this study was to determine whether using a respiratory function monitor (RFM) during mask ventilation training with a manikin reduces facemask leak.

Design: Stratified, parallel-group, randomised controlled trial. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31611
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http://dx.doi.org/10.1136/archdischild-2018-316118DOI Listing
January 2019
10 Reads

Comparison of conventional and videolaryngoscopy blades in neonates.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 3. Epub 2019 Jan 3.

Neonatal Intensive Care Unit, Royal Hospital for Children Glasgow, Glasgow, UK.

Neonatal intubation is an essential but difficult skill to learn. Videolaryngoscopy allows the airway view to be shared by the intubator and supervisor and improves intubation success. Ideally, a videolaryngoscope (VL) should be usable as a conventional laryngoscope (CL). Read More

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http://dx.doi.org/10.1136/archdischild-2018-315644DOI Listing
January 2019
1 Read

Neonatal cutaneous lupus erythematosus.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 22;104(2):F191. Epub 2018 Dec 22.

Department of Neonatology and Pediatrics, Complexo Hospitalario Universitario de A Coruña, A Coruña, Spain.

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http://dx.doi.org/10.1136/archdischild-2018-316147DOI Listing
March 2019
2 Reads

Therapeutic hypothermia for mild neonatal encephalopathy: a systematic review and meta-analysis.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 19. Epub 2018 Dec 19.

Centre for Perinatal Neuroscience, Imperial College London, London, UK.

Objectives: To examine if therapeutic hypothermia reduces the composite outcome of death, moderate or severe disability at 18 months or more after mild neonatal encephalopathy (NE).

Data Source: MEDLINE, Cochrane database, Scopus and ISI Web of Knowledge databases, using 'hypoxic ischaemic encephalopathy', 'newborn' and 'hypothermia', and 'clinical trials' as medical subject headings and terms. Manual search of the reference lists of all eligible articles and major review articles and additional data from the corresponding authors of selected articles. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31571
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http://dx.doi.org/10.1136/archdischild-2018-315711DOI Listing
December 2018
32 Reads

Assessment of resistance of nasal continuous positive airway pressure interfaces.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 19. Epub 2018 Dec 19.

Monash Newborn, Monash Medical Centre, Clayton, Victoria, Australia.

Objective: To compare the resistance of interfaces used for the delivery of nasal continuous positive airway pressure (CPAP) in neonates, as measured by the generated system pressure at fixed gas flows, in an in vitro setting.

Design: Gas flows of 6, 8 and 10 L/min were passed through three sizes of each of a selection of available neonatal nasal CPAP interfaces (Hudson prong, RAM Cannula, Fisher & Paykel prong, Infant Flow prong, Fisher & Paykel mask, Infant Flow mask). The expiratory limb was occluded and pressure differential measured using a calibrated pressure transducer. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31583
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http://dx.doi.org/10.1136/archdischild-2018-315838DOI Listing
December 2018
8 Reads

Neonatal orbital swelling due to intracranial teratoma.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 14. Epub 2018 Dec 14.

Department of Paediatric Medicine, KK Women's and Children's Hospital, Singapore, Singapore.

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31633
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http://dx.doi.org/10.1136/archdischild-2018-316337DOI Listing
December 2018
10 Reads

Understanding the principle biophysics concepts of pulmonary surfactant in health and disease.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 14. Epub 2018 Dec 14.

Department of Biochemistry and Molecular Biology, Faculty of Biology, Complutense University, Madrid, Spain.

Pulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate structure of mammalian alveoli along with successive compression-expansion respiratory cycles. To do so, surfactant reduces dramatically surface tension at the air-liquid interface, an activity that depends critically on a proper lipid composition and the presence of some specific surfactant proteins. Lack or dysfunction of this system is associated with severe respiratory pathologies, which are in some cases treated by supplementation with exogenous surfactant materials. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315413DOI Listing
December 2018
1 Read

Milk feed osmolality and adverse events in newborn infants and animals: a systematic review.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 6. Epub 2018 Dec 6.

Danone Nutricia Research, Utrecht, The Netherlands.

Background: High feed osmolality (or osmolarity) is often suggested to be linked with adverse gastrointestinal events in preterm infants.

Aim: To systematically review the literature on milk feed osmolality and adverse gastrointestinal events in newborn and low birthweight infants and animals.

Methods: MEDLINE, Embase, CAB Abstracts, Current Contents, BIOSIS Previews and SciSearch were searched from inception to May 2018 to identify potentially relevant studies. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315946DOI Listing
December 2018
3 Reads
3.120 Impact Factor

Appraisal of a scoring instrument for training and testing neonatal intubation skills.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 1. Epub 2018 Dec 1.

Department of Neonatology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.

Objective: To determine the validity, reliability, feasibility and applicability of a neonatal intubation scoring instrument.

Design: Prospective observational study.

Setting: Simulation-based research and training centre (Center for Advanced Pediatric and Perinatal Education), California, USA. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31522
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http://dx.doi.org/10.1136/archdischild-2018-315221DOI Listing
December 2018
12 Reads

Benefits of recording and reviewing neonatal resuscitation: the providers' perspective.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 1. Epub 2018 Dec 1.

Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands.

Objective: To assess benefits of recording and reviewing neonatal resuscitation as experienced by neonatal care providers.

Design: A qualitative study using semistructured interviews questioning neonatal care providers about their experiences with recording and reviewing neonatal resuscitation. Data were analysed using the qualitative data analysis software Atlas. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315648DOI Listing
December 2018
2 Reads

Establishing a composite neonatal adverse outcome indicator using English hospital administrative data.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 28. Epub 2018 Nov 28.

Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, UK.

Objective: We adapted a composite neonatal adverse outcome indicator (NAOI), originally derived in Australia, and assessed its feasibility and validity as an outcome indicator in English administrative hospital data.

Design: We used Hospital Episode Statistics (HES) data containing information infants born in the English National Health Service (NHS) between 1 April 2014 and 31 March 2015. The Australian NAOI was mapped to diagnoses and procedure codes used within HES and modified to reflect data quality and neonatal health concerns in England. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31514
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http://dx.doi.org/10.1136/archdischild-2018-315147DOI Listing
November 2018
4 Reads

EEG for the assessment of neurological function in newborn infants immediately after birth.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 26. Epub 2018 Nov 26.

Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.

Objective: To assess the neurological function of newborn infants in the first minutes after birth using EEG.

Design And Patients: We obtained electroencephalography (EEG) recordings in term infants following elective caesarean section. After delivery, disposable EEG electrodes were attached to the infants' scalp over the frontal and central regions bilaterally and EEG was recorded for 10 min. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315231DOI Listing
November 2018
2 Reads

Staff matter too: pilot staff support intervention to reduce stress and burn-out on a neonatal intensive care unit.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 26. Epub 2018 Nov 26.

Neonatal Intensive Care Unit, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316217DOI Listing
November 2018
2 Reads

Accuracy of real-time delivery room resuscitation documentation.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 24. Epub 2018 Nov 24.

Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

Objective: To assess the accuracy of real-time delivery room resuscitation documentation.

Design: Retrospective observational study.

Setting: Level 3 academic neonatal intensive care unit. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31572
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http://dx.doi.org/10.1136/archdischild-2018-315723DOI Listing
November 2018
3 Reads

Characterisation of neonatal seizures and their treatment using continuous EEG monitoring: a multicentre experience.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 24. Epub 2018 Nov 24.

Irish Centre for Fetal and Neonatal Translational Research (INFANT), Cork, Ireland.

Objective: The aim of this multicentre study was to describe detailed characteristics of electrographic seizures in a cohort of neonates monitored with multichannel continuous electroencephalography (cEEG) in 6 European centres.

Methods: Neonates of at least 36 weeks of gestation who required cEEG monitoring for clinical concerns were eligible, and were enrolled prospectively over 2 years from June 2013. Additional retrospective data were available from two centres for January 2011 to February 2014. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315624DOI Listing
November 2018
17 Reads

Social gradient of birthweight in England assessed using the INTERGROWTH-21 gestational age-specific standard.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 21. Epub 2018 Nov 21.

Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.

Objective: To determine the socioeconomic gradient of birthweights in England with reference to the prescriptive INTERGROWTH-21 Birthweight Standard.

Design: National cross-sectional study using data from Hospital Episode Statistics.

Setting: National Health Service in England. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315295DOI Listing
November 2018
16 Reads

Randomised cross-over study of automated oxygen control for preterm infants receiving nasal high flow.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 21. Epub 2018 Nov 21.

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Objective: To evaluate a prototype automated controller (IntellO) of the inspired fraction of oxygen (FiO) in maintaining a target range of oxygen saturation (SpO) in preterm babies receiving nasal high flow (HF) via the Vapotherm Precision Flow.

Design: Prospective two-centre order-randomised cross-over study.

Setting: Neonatal intensive care units. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315342DOI Listing
November 2018
21 Reads

Current use of probiotics to prevent necrotising enterocolitis.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 21;104(2):F228. Epub 2018 Nov 21.

Neonatal Unit, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316199DOI Listing
March 2019
11 Reads

Premature small for gestational age infants fed an exclusive human milk-based diet achieve catch-up growth without metabolic consequences at 2 years of age.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Section of Neonatology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA.

Objective: To compare postdischarge growth, adiposity and metabolic outcomes of appropriate for gestational age (AGA) versus small for gestational age (SGA) premature infants fed an exclusive human milk (HM)-based diet in the neonatal intensive care unit.

Design: Premature infants (birth weight ≤1250 g) fed an exclusive HM-based diet were examined at 12-15 months corrected gestational age (CGA) (visit 1) for anthropometrics, serum glucose and non-fasting insulin, and at 18-22 months CGA (visit 2) for body composition by dual-energy X-ray absorptiometry.

Results: Of 51 children, 33 were AGA and 18 were SGA at birth. Read More

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http://dx.doi.org/10.1136/archdischild-2017-314547DOI Listing
November 2018
1 Read

Network meta-analysis explained.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13;104(1):F8-F12. Epub 2018 Nov 13.

Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/archdischild-2018-315224DOI Listing
January 2019
1 Read

Randomised study comparing heart rate measurement in newly born infants using a monitor incorporating electrocardiogram and pulse oximeter versus pulse oximeter alone.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

National Maternity Hospital, Dublin, Ireland.

Aim: To determine whether IntelliVue (ECG plus Masimo pulse oximeter (PO)) measures heart rate (HR) in low-risk newborns more quickly than Nellcor PO (PO alone).

Methods: Unmasked parallel group randomised (1:1) study.

Results: We studied 100 infants, 47 randomised to IntelliVue, 53 to Nellcor. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2017-31436
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http://dx.doi.org/10.1136/archdischild-2017-314366DOI Listing
November 2018
12 Reads

Therapeutic hypothermia initiated within 6 hours of birth is associated with reduced brain injury on MR biomarkers in mild hypoxic-ischaemic encephalopathy: a non-randomised cohort study.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Centre for Perinatal Neuroscience, Imperial College London, London, UK.

Objective: To examine the effect of therapeutic hypothermia on MR biomarkers and neurodevelopmental outcomes in babies with mild hypoxic-ischaemic encephalopathy (HIE).

Design: Non-randomised cohort study.

Setting: Eight tertiary neonatal units in the UK and the USA. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31604
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http://dx.doi.org/10.1136/archdischild-2018-316040DOI Listing
November 2018
33 Reads

Epidemiology and healthcare factors associated with neonatal enterococcal infections.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.

Objective: To investigate the epidemiology and healthcare factors associated with late-onset neonatal enterococcal infections.

Design: Multicentre, multinational retrospective cohort study using prospectively collected infection data from a neonatal infection surveillance network between 2004 and 2016; this was supplemented with healthcare data from a questionnaire distributed to participating neonatal units.

Setting: Sixty neonatal units across Europe (UK, Greece, Estonia) and Australia. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31538
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http://dx.doi.org/10.1136/archdischild-2018-315387DOI Listing
November 2018
16 Reads

Continuous glucose monitoring in the neonatal intensive care unit: not quite ready for 'plug and play'.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Department of Pediatrics, Perinatal Research Center, University of Colorado School of Medicine, Aurora, Colorado, USA.

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http://dx.doi.org/10.1136/archdischild-2018-315899DOI Listing
November 2018
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Challenges and opportunities for antibiotic stewardship among preterm infants.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Antibiotic stewardship programmes aim to optimise antimicrobial use to prevent the emergence of resistance species and protect patients from the side effects of unnecessary medication. The high incidence of systemic infection and associated mortality from these infections leads neonatal providers to frequently initiate antibiotic therapy and make empiric antibiotic courses one of the main contributors of antibiotic use in the neonatal units. Yet, premature infants are also at risk for acute life-threatening complications associated with antibiotic use such as necrotising enterocolitis and for long-term morbidities such as asthma. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31541
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http://dx.doi.org/10.1136/archdischild-2018-315412DOI Listing
November 2018
24 Reads

Cerebral autoregulation in premature infants during the first 96 hours of life and relationship to adverse outcomes.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 1. Epub 2018 Nov 1.

Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Objective: To test the hypothesis that impaired cerebral autoregulation (ICA) increases the susceptibility of premature infants to adverse outcomes, we determined the relationship of ICA and cerebral reactivity (CR) measured in the first 96 hours of life to the outcome of grade 3 or 4 intraventricular haemorrhage (IVH) and/or death within 1 month.

Setting: Single-centre level IV neonatal intensive care unit.

Patients: Neonates 24-29 weeks' gestation less than 12 hours old with invasive blood pressure monitoring. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315725DOI Listing
November 2018
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Point-of-care measurements of blood ketones in newborns.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 1. Epub 2018 Nov 1.

Liggins Institute, University of Auckland, Auckland, New Zealand.

Objective: Babies may use alternative cerebral fuels including ketones when blood glucose concentrations are low, but laboratory ketone measurements are slow and expensive. Point-of-care measurement of ketone concentrations, if sufficiently accurate, may provide useful information for clinical care.

Patients And Design: Eligible babies were 35-42 weeks' gestation, ≤10 days old and admitted to the newborn intensive care unit. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31629
Publisher Site
http://dx.doi.org/10.1136/archdischild-2018-316293DOI Listing
November 2018
19 Reads