9,255 results match your criteria Archives of Oral Biology[Journal]


Force-induced decline of TEA domain family member 1 contributes to osteoclastogenesis via regulation of Osteoprotegerin.

Arch Oral Biol 2019 Jan 31;100:23-32. Epub 2019 Jan 31.

Department of Orthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, China. Electronic address:

Objective: This study aims to investigate the responsiveness of transcription factor TEA domain family member 1 (TEAD1) to mechanical force and its impact on osteoclastogenesis as well as expression of Osteoprotegerin (OPG), an inhibitor for osteoclastogenesis playing crucial roles in mechanical stress-induced bone remodeling and orthodontic tooth movement (OTM).

Methods: We first analyzed the correlation between several transcription factors and OPG expression in human periodontal ligament cells (PDLCs). Then dynamic expression changes of TEAD1 with force application were analyzed due to its high correlation with OPG. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.020DOI Listing
January 2019

Heterogeneous localization of muscarinic cholinoceptor M in the salivary ducts of adult mice.

Arch Oral Biol 2019 Feb 4;100:14-22. Epub 2019 Feb 4.

Electron Microscopy Laboratory, Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. Electronic address:

We hypothesize variation in expression and localization, along the course of the glandular tubule, of muscarinic cholinergic receptor M which plays as a distinct contribution, though minor in comparison with M receptor, in saliva secretion. Localization of the M receptor was examined using immunohistochemistry in three major salivary glands. Although all glandular cells were more or less M-immunoreactive, acinar cells were weakly immunoreactive, while ductal cells exhibited substantial M-immunoreactivity. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.02.001DOI Listing
February 2019

Influence of low-level laser therapy on orthodontically-induced inflammatory root resorption. A systematic review.

Arch Oral Biol 2019 Jan 30;100:1-13. Epub 2019 Jan 30.

Laboratory for Periodontal-, Implant-, Phototherapy (LA-PIP), School of Dental Medicine, Stony Brook University, Stony Brook, NY, USA; Department of Periodontology, School of Dental Medicine, Stony Brook University, Stony Brook, NY, USA.

Objective: The aim was to assess the influence of low-level laser therapy (LLLT) on orthodontically-induced inflammatory root resorption (OIIRR).

Methods: A systematic search was conducted in indexed databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The eligibility criteria were as follows: (a) original clinical and animal/experimental studies; (b) prospective studies; (c) intervention: effect of LLLT on OIIRR; (d) control group (OIIRR without LLLT); (e) statistical analysis; and (f) tomographic or histologic assessment of OIIRR. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.017DOI Listing
January 2019

Deletion of cas3 gene in Streptococcus mutans affects biofilm formation and increases fluoride sensitivity.

Arch Oral Biol 2019 Jan 29;99:190-197. Epub 2019 Jan 29.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:

Objective: The goal of this study was to analyze the impact of cas3 gene on the biofilm formation and virulence gene expression in S. mutans, since our previous studies have found a connection between CRISPR/Cas systems and biofilm formation in S. mutans. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.016DOI Listing
January 2019
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Serum-based metabolomics characterization of patients with reticular oral lichen planus.

Arch Oral Biol 2019 Jan 30;99:183-189. Epub 2019 Jan 30.

First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, PR China. Electronic address:

Objective: Oral lichen planus (OLP) is a chronic inflammatory mucosal lesion and systemic disease. In OLP, reticular type is the most common presentation of the disease. However, little is known about it. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.019DOI Listing
January 2019
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Clinicopathological significance of tumor cyclin D1 expression in oral cancer.

Arch Oral Biol 2019 Jan 30;99:177-182. Epub 2019 Jan 30.

School of Dentistry, University of Granada, Granada, Spain; Instituto de Investigación Biosanitaria, Granada, Spain. Electronic address:

Objective: To evaluate the association of cyclin D1 overexpression with clinicopathological parameters classically considered of prognostic value in OSCC (T, N, M, clinical stage, degree of differentiation, invasive morphology and, cellular proliferation index).

Design: A retrospective immunohistochemical study was conducted of cyclin D1 and ki-67 expression in 68 OSCCs from 54 patients. Cases were scanned using a digital pathology system. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.018DOI Listing
January 2019

Comparison of the oral microbiome of patients with generalized aggressive periodontitis and periodontitis-free subjects.

Arch Oral Biol 2019 Jan 28;99:169-176. Epub 2019 Jan 28.

Department of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Germany.

Objective: The primary objectives of the study were to assess differences in complex subgingival bacterial composition between periodontitis-free persons and patients with generalized aggressive periodontitis (gAgP).

Background: The composition of the oral microbiota plays an important role for both oral and systemic diseases. However, the complex nature of the oral microbiome and its homeostasis is still poorly understood. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.015DOI Listing
January 2019
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Effects of continuous and intermittent parathyroid hormone administration on midpalatal suture expansion in rats.

Arch Oral Biol 2019 Jan 25;99:161-168. Epub 2019 Jan 25.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontic and Pediatric dentistry, West China Hospital of Stomatology, Sichuan University, China.

Objectives: The aim of this study was to investigate the effects of continuous parathyroid hormone (cPTH) and intermittent parathyroid hormone (iPTH) on bone formation and bone resorption in midpalatal suture during maxillary expansion.

Methods: Forty-eight male SD rats were randomly divided into four groups (n = 12 each), including the control, the expansion (E), the E + cPTH, and the E + iPTH. A thermosensitive controlled-release hydrogel was synthesized for cPTH administration. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.014DOI Listing
January 2019
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Effect of Er,Cr:YSGG laser associated with fluoride on the control of enamel erosion progression.

Arch Oral Biol 2019 Jan 17;99:156-160. Epub 2019 Jan 17.

Special Laboratory of Lasers in Dentistry (LELO), Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes 2227, São Paulo, SP, 05508-000. Electronic address:

Objective: To evaluate the effect of Er,Cr:YSGG laser associated or not with acidulated phosphate fluoride (APF) on the control of enamel erosion progression.

Design: Enamel slabs (4 mm × 4 mm × 2 mm) from bovine incisors were flattened, polished, and received a tape on their test surfaces, leaving a 4 mm × 1 mm area exposed. Specimens were eroded (10 min in 1% citric acid solution) and randomly assigned into 8 experimental groups (n = 10): Control (no treatment); F (APF gel, 1. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.011DOI Listing
January 2019

Cellular senescence in dental pulp stem cells.

Arch Oral Biol 2019 Jan 17;99:150-155. Epub 2019 Jan 17.

Department of Oral and Maxillofacial Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany. Electronic address:

Objective: This short review summarizes our current knowledge about dental stem cell aging and about possible targets for the regulation of cellular senescence.

Design: A literature search was performed using a combination of keywords, e.g. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.012DOI Listing
January 2019
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Tooth extraction and subsequent dental implant placement in Sprague-Dawley rats induce differential changes in anterior digastric myofibre size and myosin heavy chain isoform expression.

Arch Oral Biol 2019 Jan 16;99:141-149. Epub 2019 Jan 16.

Prosthodontics, Faculty of Dentistry, University of Toronto, 124 Edward St., Toronto, Ontario, M5G 1G6, Canada. Electronic address:

Objective: to determine if tooth loss and dental implant placement in rats induce changes in the morphological and histochemical features of the Anterior Digastric muscle.

Design: Adult male Sprague-Dawley rats had their right maxillary molar teeth extracted. 'Extraction-1' and 'Extraction-2 groups were sacrificed, respectively, 4 or 8 weeks later, and an Implant group had an implant placement 2 weeks after the molar extraction, and rats were sacrificed 3 weeks later (n = 4/group). Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.009DOI Listing
January 2019
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Jagged1 promotes mineralization in human bone-derived cells.

Arch Oral Biol 2019 Jan 18;99:134-140. Epub 2019 Jan 18.

Department of Prosthodontics, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.

Objectives: The present study aimed to investigate the expression of Notch signaling components during osteogenic differentiation in vitro and bone healing in vivo. In addition, the influence of Notch signaling on osteogenic differentiation of human bone-derived cells was examined.

Methods: Gene expression profiling of osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells in vitro (GSE80614) and bone healing period of murine tibial fracture in vivo (GSE99388) was downloaded from Gene Expression Omnibus database. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.013DOI Listing
January 2019
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Oxytocin facilitates the proliferation, migration and osteogenic differentiation of human periodontal stem cells in vitro.

Arch Oral Biol 2019 Jan 19;99:126-133. Epub 2019 Jan 19.

Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong Province, China; Department of Periodontology, School of Stomatology, Shandong University, Jinan, Shandong Province, China. Electronic address:

Objective: To explore the effect of oxytocin (OT) on the proliferation, migration, and osteogenic differentiation of periodontal ligament stem cells (PDLSCs) in vitro.

Design: PDLSCs were obtained by limiting dilution method. Immunofluorescence (IF), cell-counting kit-8 (CCK8), cell migration assay, Alizarin Red S staining, cetylpyridinium chloride (CPC) colorimetry, quantitative real-time polymerase chain reaction (qRT-PCR), and western blot analysis were used to examine the effect of OT on oxytocin receptor (OTR) expression, cell proliferation, migration and osteogenic differentiation of PDLSCs. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.007DOI Listing
January 2019
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Porphyromonas gingivalis lipopolysaccharide-induced periodontitis and serum amyloid-beta peptides.

Arch Oral Biol 2019 Jan 16;99:120-125. Epub 2019 Jan 16.

Clinical Neurosciences Research Laboratory, Clinical University Hospital, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain. Electronic address:

Objective: The aim of this investigation was to determine the circulating levels of amyloid beta (Aβ) peptides using the Porphyromonas gingivalis (Pg) lipopolysaccharide (LPS) model to induce periodontitis.

Methods: Experimental periodontitis was induced in 6 male Sprague-Dawley rats. Alveolar bone loss was measure by micro computed tomography. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.008DOI Listing
January 2019
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Antifungal activities against Candida albicans, of cell-free supernatants obtained from probiotic Pediococcus acidilactici HW01.

Arch Oral Biol 2019 Jan 11;99:113-119. Epub 2019 Jan 11.

Department of Food Science and Biotechnology, College of Life Science and Biotechnology, Dongguk University-Seoul, Goyang 10326, Republic of Korea. Electronic address:

Objective: The aim of this study was to investigate the antifungal activities of cell-free supernatants of a probiotic strain, Pediococcus acidilactici HW01, against Candida albicans.

Design: C. albicans was cultured in the presence of different concentration of cell-free supernatants obtained from P. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.006DOI Listing
January 2019
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Down-regulation of mitochondrial NADH and cytochrome b gene associated with high tumor stages in head and neck squamous cell carcinoma.

Arch Oral Biol 2019 Jan 10;99:107-112. Epub 2019 Jan 10.

Department of Oral Biology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand. Electronic address:

Objective: This study aimed to determine mitochondrial mRNA expression levels and the relationships between these expression levels and various adverse clinicopathological characteristics.

Methods: The mRNA expression levels of all 12 genes encoded protein, located on the heavy-strand of mitochondrial DNA including cytochrome b, NADH1, NADH2, NADH3, NADH4, NADH4L, NADH5, ATPase6, ATPase8, cytochrome c oxidase subunit 1, cytochrome c oxidase subunit 2, cytochrome c oxidase subunit 3 were analyzed in 30 head and neck squamous cell carcinoma (HNSCC) and the corresponding normal tissues using reverse transcriptase quantitative real time PCR. Pearson Chi-square test was used to determine the relationships between these expression levels and categorical parameters. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00039969183050
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http://dx.doi.org/10.1016/j.archoralbio.2019.01.005DOI Listing
January 2019
4 Reads

Cancer Stem Cell based molecular predictors of tumor recurrence in Oral squamous cell carcinoma.

Arch Oral Biol 2019 Jan 4;99:92-106. Epub 2019 Jan 4.

Integrated Head and Neck Oncology Program, Mazumdar Shaw Medical Foundation, Mazumdar Shaw Medical Center, Narayana Health City, Bommasandra Industrial Area, Anekal Taluk, Bangalore, 560099, Karnataka, India; Department of Head and Neck Oncology, Mazumdar Shaw Medical Center, Narayana Health City, Bommasandra Industrial Area, Anekal Taluk, Bangalore, 560099, Karnataka, India; Mazumdar Shaw Medical Centre-Roswell Park Collaboration Program, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, 14263, New York, USA. Electronic address:

Objective: This study aimed to identify the cancer stem cell specific biomarkers that can be effective candidate prognosticators of oral squamous cell carcinoma.

Design: Microarray-based meta-analysis derived transcriptional profile of head and neck cancers was compared with the Cancer Stem Cell database to arrive at a subset of markers. This subset was further co-related with clinico-pathological parameters, recurrence and survival of oral cancer patients (n = 313) in The Cancer Genome Atlas database and in oral cancer (n = 28) patients. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.002DOI Listing
January 2019
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Biomarkers of inflammatory external root resorption as a result of traumatic dental injury to permanent teeth in children.

Arch Oral Biol 2019 Jan 7;99:82-91. Epub 2019 Jan 7.

Institute of Dentistry, Jagiellonian University Medical College, Krakow, Poland.

Objective: External inflammatory root resorption (EIRR) is a common complication of traumatic dental injury (TDI) that can be detected radiologically. During EIRR, various proteins are released into gingival sulcus fluid (GCF). The aim of the study was to monitor the levels of selected proteins in GCF in children (8-16 years of age) in order to assess their utility in the early diagnosis of EIRR. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.003DOI Listing
January 2019
2 Reads

Differential growth of craniofacial and tibial bones to sympathetic hyperactivity-related hypertension in rats.

Arch Oral Biol 2019 Jan 3;99:73-81. Epub 2019 Jan 3.

Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

Objective: To evaluate the effect of sympathetic nervous system hyperactivity on craniofacial skeletal growth in growing spontaneously hypertensive rats (SHRs).

Design: Craniofacial skeletal growth was compared between male SHR and Wistar-Kyoto rats (WKR) using linear measurements on lateral and transverse cephalometric radiographs at the age of 12 weeks. Tibia length was measured as an index of whole body growth. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.001DOI Listing
January 2019
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Mental nerve injury induces novelty seeking behaviour leading to increasing ethanol intake in Wistar rats.

Arch Oral Biol 2019 Jan 7;99:66-72. Epub 2019 Jan 7.

Laboratorio de Neurofarmacología Conductual, Unidad Interdisciplinaria en ciencias de la Salud y la Eduación. Facultad de Estudios Superiores Iztacala, UNAM, Av De Los Barrios 1, Los Reyes Ixtacala, Hab Los Reyes Ixtacala Barrio de los Árboles/Barrio de los Héroes, 54090 Tlalnepantla, Mexico.

Objective: Dental treatment and orofacial surgeries may induce chronic neuropathic orofacial pain (CNOP). This kind of pain affects adaptability to environmental changes in both model animals and humans. Part of the adaptation process depends on the ability to distinguish between familiar and novel stimuli. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.004DOI Listing
January 2019
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Effect of dentinal fluid on enamel permeability under simulated pulpal pressure.

Arch Oral Biol 2018 Dec 26;99:58-65. Epub 2018 Dec 26.

Department of Stomatology, Faculty of Dentistry, Srinakharinwirot University, 114 Sukhumvit 23rd, Bangkok 10110, Thailand. Electronic address:

Objective: To determine the effect of pulpal perfusion on the fluid flow through human tooth after different treatments at the enamel surface. Changes in mineral density along with fluid flow rate were also analyzed before and after etching.

Design: The experiments were carried out on 97 human premolars. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.010DOI Listing
December 2018
1 Read

Factors associated with masticatory performance and swallowing threshold according to dental formula development.

Arch Oral Biol 2018 Dec 31;99:51-57. Epub 2018 Dec 31.

Division of Developmental Stomatognathic Function Science, Department of Health Promotion, Kyushu Dental University, Kitakyushu City, Japan.

Objective: The aims of the present study were to the determine changes in, and factors related to, masticatory performance and swallowing threshold according to dental formula development.

Methods: A total of 120 subjects, ranging in age from 4 to 19, and 21 to 29 years, were included in the present study. Grip strength and maximum occlusal force were measured in all subjects. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.012DOI Listing
December 2018
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Sclerostin injection enhances orthodontic tooth movement in rats.

Arch Oral Biol 2018 Dec 26;99:43-50. Epub 2018 Dec 26.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, China. Electronic address:

Objective: It was aimed to investigate the in vivo effects of local injection of sclerostin protein on orthodontic tooth movement.

Design: A total of 48 rats underwent orthodontic mesialization of the maxillary first molars on both sides. Local injection was given at the compression side in the alveolar bone on both maxillary sides, with sclerostin protein carried by hydrogel on one side, and the same volume of normal saline carried by hydrogel on the other side serving as the control. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.011DOI Listing
December 2018
2 Reads

Human salivary proteins and their peptidomimetics: Values of function, early diagnosis, and therapeutic potential in combating dental caries.

Arch Oral Biol 2018 Dec 24;99:31-42. Epub 2018 Dec 24.

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China. Electronic address:

Saliva contains a large number of proteins that play various crucial roles to maintain the oral health and tooth integrity. This oral fluid is proposed to be one of the most important host factors, serving as a special medium for monitoring aspects of microorganisms, diet and host susceptibility involved in the caries process. Extensive salivary proteomic and peptidomic studies have resulted in considerable advances in the field of biomarkers discovery for dental caries. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.009DOI Listing
December 2018
1 Read
1.880 Impact Factor

Focal localization of inflammatory cytokines and neurotrophins in a tongue chronic injury model.

Arch Oral Biol 2018 Dec 19;99:22-30. Epub 2018 Dec 19.

Department of Oral Medicine, School of Dentistry, IHBR, Kyungpook National University, Daegu, Republic of Korea. Electronic address:

Objectives: Chronic injury in tongue causes the variety of reactions in the oral cavity, frequently leading to its functional and structural disintegrity including inflammation and sensory dysfunction, but its detailed profiles were not elucidated yet. One of the chronically injured tongue such as tongue piercing, as a pathological aspect, is currently popular among younger people but may be associated with severe side effects, leading to pathophysiological complications. However, the pathophysiological aspects and related cellular and molecular mechanisms underlying tongue injury are not clearly understood. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.008DOI Listing
December 2018
2 Reads

Salivary opiorphin in dental pain: A potential biomarker for dental disease.

Arch Oral Biol 2018 Dec 15;99:15-21. Epub 2018 Dec 15.

Department of Clinical Sciences, School of Dentistry, Ankara Yildirim Beyazit University, Ankara, Turkey. Electronic address:

Objectives: Opiorphin is a recently discovered peptide shown to inhibit the enkephalin-degrading enzymes and prolong the effects of enkephalins. Although opiorphin is found in high concentrations in saliva, the relationship between salivary opiorphin and orofacial pains is not yet fully understood. We aimed to determine salivary opiorphin concentrations in dental pain related to symptomatic irreversible pulpitis (SIP), and symptomatic apical periodontitis (SAP). Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.006DOI Listing
December 2018
2 Reads

Is there any association between green tea consumption and the risk of head and neck squamous cell carcinoma: Finding from a case-control study.

Arch Oral Biol 2019 Feb 7;98:280-284. Epub 2018 Dec 7.

Assistant professor of Surgery Oncology, Department of Surgery, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Objective: Green tea consumption has been shown to reduce the incidence of head and neck squamous cell carcinoma (HNSCC) in experimental animal models, however the results from human studies are inconclusive. The aim of this study was to evaluate the relationship between green tea consumption and the risk of HNSCC.

Design: The study utilised a standardised questionnaire to investigate the relationship between green tea consumption and HNSCC experience. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.003DOI Listing
February 2019
3 Reads

Polymorphism of reduced folate carrier 1 (A80G) and non-syndromic cleft lip/palate: A systematic review and meta-analysis.

Arch Oral Biol 2019 Feb 11;98:273-279. Epub 2018 Dec 11.

Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran; Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address:

Objective: To evaluate the association between polymorphism of reduced folate carrier 1 (RFC1) A80 G in infants and the risk of non-syndromic cleft lip/palate (NSCL/P), in a meta-analysis of case-control studies.

Design: We searched databases of PubMed, Scopus, Web of Science, and Cochrane Library for studies on the association of mentioned polymorphism and NSCL/P risk published until August 2018.

Results: Seven articles were selected based on the criteria and were analyzed in this meta-analysis (1486 NSCL/P patients and 1596 controls). Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.005DOI Listing
February 2019
1 Read
1.880 Impact Factor

Polymorphisms associated with oral clefts as potential susceptibility markers for oral and breast cancer.

Arch Oral Biol 2018 Dec 14;99:9-14. Epub 2018 Dec 14.

Stomatology Clinic, Dental School, State University of Montes Claros, Montes Claros, Minas Gerais, Brazil.

Objective: To evaluate the association of single nucleotide polymorphisms (SNPs) in genes/loci consistently altered in nonsyndromic oral clefts in patients with oral and breast cancer in a Brazilian population.

Design: This case-control study evaluated the association of SNPs in IRF6 (rs642961), WNT3A (rs708111), GSK3β (rs9879992), 8q24 (rs987525) and WNT11 (rs1533767), representing regions consistently identified as of susceptibility for oral clefts, with oral cancer (oral squamous cell carcinoma) and breast cancer. Logistic regression analyses were used for confounding adjustments, and p values ≤0. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.004DOI Listing
December 2018
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Clinical and histopathologic prognostic implications of the expression of cytokeratins 8, 10, 13, 14, 16, 18 and 19 in oral and oropharyngeal squamous cell carcinoma.

Arch Oral Biol 2018 Dec 16;99:1-8. Epub 2018 Dec 16.

King Hussein Cancer Center, Amman, Jordan.

Objectives: To identify cytokeratins (CK) of significant correlations with clinical and histopathologic prognostic parameters in oral and oropharyngeal squamous cell carcinoma (SCC).

Design: The sample consisted of 100 cases retrieved from the archives of the Pathology Department/ King Hussein Cancer Center/Amman/ Jordan. Recorded data included: age, gender, location, grade, depth of invasion, the presence of epithelial dysplasia, tumor size, lymph node metastasis, number of positive lymph nodes, distant metastases, clinical stage, local recurrence, treatment modalities and 5-year survival rate. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.007DOI Listing
December 2018
2 Reads
1.880 Impact Factor

Methylation status of SFRP1, SFRP2, RASSF1A, RARβ and DAPK1 genes in patients with oral squamous cell carcinoma.

Arch Oral Biol 2019 Feb 3;98:265-272. Epub 2018 Dec 3.

Department of Statistics, Department of Instrumental Analysis, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Ostrogórska 30 Str., 41-200 Sosnowiec, Medical University of Silesia in Katowice, Poland. Electronic address:

Our study assessed the methylation status of the SFRP1, SFRP2, RASSF1A, RARβ and DAPK1 genes, which are associated with epigenetic silencing in cancers. In a group of 75 patients with oral squamous cell carcinoma, aberrant methylation was detected using methylation-specific PCR in tumours and matched margins. Our results showed significantly higher methylation frequency in tumours than in surgical margin of SFRP2 (26. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.001DOI Listing
February 2019
1 Read

Development and validation of mathematical models for testing antifungal activity of different essential oils against Candida species.

Arch Oral Biol 2019 Feb 1;98:258-264. Epub 2018 Dec 1.

National Reference Medical Mycology Laboratory, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, dr Subotića 1, 11000, Belgrade, Serbia.

Objective: The upward trend in using plant materials introduced essential oils (EOs) as a valuable, novel, bioactive antifungal agent and as an alternative to standard treatment protocol of denture stomatitis caused by Candida species. Therefore, the aim was to evaluate the antifungal activity of different EOs and to present the response surface methodology (RSM) and artificial neural network (ANN) as possible tools for optimizing and predicting EOs antifungal activity.

Methods: Minimum inhibitory concentration (MIC) and Minimum fungicidal concentration (MFC) of the EOs against 3 species Candida spp. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.029DOI Listing
February 2019
1 Read

Biomechanically stimulated chondrocytes promote osteoclastic bone resorption in the mandibular condyle.

Arch Oral Biol 2019 Feb 3;98:248-257. Epub 2018 Dec 3.

Department of Dentistry, The 986rd Hospital of PLA Air Force, Xi'an, 710054, China.

Objective: Chondrocyte signaling is important in osteoclastic bone resorption in mice tibiae. The present study aimed to test whether biomechanically stimulated chondrocytes promote osteoclastic bone resorption in the mandibular condyle.

Methods: Primary chondrocytes isolated from rat condylar cartilage were stimulated by fluid flow shear stress (FSS) for 30, 60, 120 min at intensities of 10, 20, or 30 dynes/cm. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.12.002DOI Listing
February 2019
2 Reads

Effects of Lactobacillus salivarius WB21 combined with green tea catechins on dental caries, periodontitis, and oral malodor.

Arch Oral Biol 2019 Feb 30;98:243-247. Epub 2018 Nov 30.

Department of General Dentistry, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan. Electronic address:

Objective: To evaluate the combined use of Lactobacillus salivarius WB21 and (-)-epigallocatechin gallate (EGCg) for oral health maintenance.

Design: The effects of L. salivarius WB21 on growth of Streptococcus mutans, the insoluble glucan produced by S. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.027DOI Listing
February 2019
4 Reads

Effects of anterior tongue strengthening exercises on posterior tongue strength in healthy young adults.

Arch Oral Biol 2019 Feb 28;98:238-242. Epub 2018 Nov 28.

Kawasaki University of Medical Welfare, 288 Matsushima, Kurashiki, Okayama 701-0193, Japan. Electronic address:

Objective: The aim of the present study was to investigate whether anterior tongue muscle strengthening exercises can affect the strength of posterior tongue muscles.

Design: Eleven healthy subjects (20.6 ± 1. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00039969183052
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http://dx.doi.org/10.1016/j.archoralbio.2018.11.028DOI Listing
February 2019
5 Reads

The effect of unilateral lingual nerve injury on the kinematics of mastication in pigs.

Arch Oral Biol 2019 Feb 22;98:226-237. Epub 2018 Nov 22.

Ohio University Heritage College of Osteopathic Medicine, Department of Biomedical Sciences, Irvine Hall 228, Athens, OH, 45701, USA. Electronic address:

Objective: This study evaluates the effect of unilateral lingual sensory loss on the spatial and temporal dynamics of jaw movements during pig chewing.

Design: X-ray Reconstruction of Moving Morphology (XROMM) was used to reconstruct the 3-dimensional jaw movements of 6 pigs during chewing before and after complete unilateral lingual nerve transection. The effect of the transection were evaluated at the temporal and spatial level using Multiple Analysis of Variance. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340731PMC
February 2019
3 Reads

Genetic and environmental influences on third molar root mineralization.

Arch Oral Biol 2019 Feb 26;98:220-225. Epub 2018 Nov 26.

Lithuanian University of Health Sciences, Medical Academy, Clinic of Orthodontics, Lukšos- Daumanto str. 6, LT-50106, Lithuania.

Objective: To assess the genetic and environmental influences on the variability of human third molar (M3) root mineralization stages via a twin study.

Design: The study sample consisted of 162 same-sex twins (66 dizygotic and 96 monozygotic, mean age: 17.9 years) with normal growth and development. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00039969183083
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http://dx.doi.org/10.1016/j.archoralbio.2018.11.026DOI Listing
February 2019
14 Reads

Detection and quantification of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in bacteremia induced by interdental brushing in periodontally healthy and periodontitis patients.

Arch Oral Biol 2019 Feb 24;98:213-219. Epub 2018 Nov 24.

Etiology and Therapy of Periodontal Diseases (ETEP) Research Group, University Complutense, Madrid, Spain. Electronic address:

Objective: This study was aimed to compare the presence and amounts of bacteremia induced by interdental brushing in periodontally healthy (H) and periodontitis (P) individuals using culture based (direct culture [DC]) and molecular based techniques (real-time quantitative polymerase chain reaction [qPCR]) in a cross-sectional study model.

Materials And Methods: After a full mouth periodontal evaluation, blood samples were taken before and 1 min after professionally-administered interdental brushing. These samples were analyzed by DC and qPCR, targeting Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.025DOI Listing
February 2019
2 Reads

Apolipoprotein E, periodontal disease and the risk for atherosclerosis: a review.

Arch Oral Biol 2019 Feb 23;98:204-212. Epub 2018 Nov 23.

Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Fortaleza, CE, Brazil. Electronic address:

The association between cardiovascular and periodontal diseases is characterized by chronic inflammatory processes, with a high prevalence worldwide and complex genetic-environment interactions. Although apolipoprotein E4 (ApoE4), one of the isoforms coded by a polymorphic APOE gene, has been widely recognized as a risk factor for cardiovascular diseases and as an immunoinflammatory factor, less is known regarding how ApoE4 affects atherosclerosis in periodontitis patients. The aim of this review was to investigate the potential underlying mechanisms related to APOE4 that could increase the risk of periodontal disease and, ultimately, of atherosclerosis. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.009DOI Listing
February 2019
1 Read

Macrophage response and surface analysis of dental cementum after treatment with high intensity focused ultrasound.

Authors:
U Daood A S Fawzy

Arch Oral Biol 2019 Feb 19;98:195-203. Epub 2018 Nov 19.

UWA Dental School, University of Western Australia, 17 Monash Avenue, Nedlands, WA, 6009, Australia. Electronic address:

Objective: To investigate effects of HIFU on macrophage phenotype, surface micro-topography and nano-scale surface mechanical properties of dental cementum.

Materials And Methods: Root discs (2 mm thickness) were cut apical to CEJ and sectioned into quadrants. HIFU setup with bowl-shaped piezo ceramic transducer submerged in a water tank was used for exposure on each specimen for 15 s, 30 s or 60 s. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00039969183028
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http://dx.doi.org/10.1016/j.archoralbio.2018.10.019DOI Listing
February 2019
7 Reads

Screening of hydrogel-based scaffolds for dental pulp regeneration-A systematic review.

Arch Oral Biol 2019 Feb 22;98:182-194. Epub 2018 Nov 22.

Post Graduation Program, School of Dentistry, Ibirapuera University, Brazil. Electronic address:

Objective: The aim of this systematic review was to evaluate the most appropriate hydrogel scaffold type (natural, synthetic or hybrid) to be applied with stem cells for dental pulp regeneration. The findings should help clinicians make an informed choice about the appropriate scaffold to be applied for this approach.

Design: Three electronic databases were searched (Medline, Web of Science and Scopus). Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.023DOI Listing
February 2019
2 Reads

Caries, antemortem tooth loss and tooth wear observed in indigenous peoples and Russian settlers of 16th to 19th century West Siberia.

Arch Oral Biol 2019 Feb 14;98:176-181. Epub 2018 Nov 14.

Tyumen Scientific Center of the Siberian Branch of the Russian Academy of Sciences, Tyumen, Russia. Electronic address:

Objective: Increased prevalence of dental caries evidently is correlated with increasing intake of sugar and carbohydrate-rich foods. Preceding and accompanying this dietary alteration might have been a shift from a hunting-and-gathering subsistence strategy to one based on agriculture. We corroborated this conjecture by means of a study on the prevalence of caries, antemortem tooth loss (AMTL) and tooth wear among 16th to 19th century hunter-gatherers and agriculturalists who co-existed in West Siberia. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.010DOI Listing
February 2019
1 Read

Molecular docking and in silico studies of the physicochemical properties of potential inhibitors for the phosphotransferase system of Streptococcus mutans.

Arch Oral Biol 2019 Feb 22;98:164-175. Epub 2018 Nov 22.

Faculty of Dentistry, University of Antioquia- UdeA, 64 Street No. 52-59, Block 31, Oral Microbiology Laboratory No. 216, Health Area, Medellin, Colombia. Electronic address:

This study identified potential inhibitory compounds of the phosphoenolpyruvate-sugar. Phosphotransferase system of S. mutans, specifically enzyme II mannose transporter (EII) in its subunits IIA, IIB and IIC by means of a selection protocol and in silico molecular analysis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00039969183057
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http://dx.doi.org/10.1016/j.archoralbio.2018.09.020DOI Listing
February 2019
4 Reads

Betamethasone suppresses the inflammatory response in LPS-stimulated dental pulp cells through inhibition of NF-κB.

Arch Oral Biol 2019 Feb 20;98:156-163. Epub 2018 Nov 20.

Department of Pediatric Dentistry, School & Hospital of Stomatology, Peking University, Beijing, China. Electronic address:

Objective: This study aimed to investigate the anti-inflammatory effect of betamethasone on LPS-stimulated human dental pulp stem cells (DPSCs) and its associated mechanism. The osteo-/odontogenic differentiation and osteoclast effect of betamethasone on DPSCs and stem cells from human exfoliated deciduous teeth (SHED) were evaluated.

Design: The proliferative effect of betamethasone on DPSCs was analyzed using a cholecystokinin octapeptide assay. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.022DOI Listing
February 2019
1 Read

Proteomics of the acid-soluble fraction of whole and major gland saliva in burning mouth syndrome patients.

Arch Oral Biol 2019 Feb 20;98:148-155. Epub 2018 Nov 20.

Institute of Chemistry of the Molecular Recognition - CNR, L.go F. Vito 1, 00168, Rome, Italy.

Objective: In the present study the salivary proteome of burning mouth syndrome patients and healthy subjects was characterized by a top-down proteomic approach and compared to highlight possible qualitative and quantitative differences that may give suggestions about the causes of this pathology which are still unknown.

Materials And Methods: Resting and stimulated whole saliva, stimulated parotid and submandibular/sublingual saliva samples were collected from burning mouth syndrome patients (n = 16) and age- and gender-matched healthy subjects (n = 14). An equal volume of 0. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00039969183037
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http://dx.doi.org/10.1016/j.archoralbio.2018.11.020DOI Listing
February 2019
11 Reads

Patterns of congenitally missing teeth of non-syndromic and syndromic patients treated at a single-center over the past thirty years.

Arch Oral Biol 2019 Feb 16;98:140-147. Epub 2018 Nov 16.

Division of Oral Surgery, University Clinic of Dentistry, Medical University of Vienna, Austria.

Objectives: Literature regarding congenitally-missing-teeth (CMT) is lacking especially on CMT-patterns. Thus, the aim of this study was to present an in-depth analysis of 843 patients with CMT treated at a single-center over the past thirty years.

Design: Age, date-of-birth-year, gender, medical- and family-history, CMT-types, -numbers, -severity, -region, -symmetry, -patterns using the tooth agenesis code (TAC), and -growth types of all clinically and radiographically diagnosed CMT-patients were collected. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00039969183025
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http://dx.doi.org/10.1016/j.archoralbio.2018.11.018DOI Listing
February 2019
3 Reads

Peptides from rice endosperm protein restrain periodontal bone loss in mouse model of periodontitis.

Arch Oral Biol 2019 Feb 20;98:132-139. Epub 2018 Nov 20.

Division of Microbiology and Infectious Diseases, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan; Research Center for Advanced Oral Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan. Electronic address:

Objective: Food-derived peptides have been reported to exhibit antibacterial activity against periodontal pathogenic bacteria. However, no effect has been shown on inflammation and bone resorption in periodontal pathology. The overall objective of the current study was to investigate how rice peptides influence biological defense mechanisms against periodontitis-induced inflammatory bone loss, and identify their novel functions as a potential anti-inflammatory drug. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00039969183037
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http://dx.doi.org/10.1016/j.archoralbio.2018.11.021DOI Listing
February 2019
2 Reads

Leptin stimulates DMP-1 and DSPP expression in human dental pulp via MAPK 1/3 and PI3K signaling pathways.

Arch Oral Biol 2019 Feb 20;98:126-131. Epub 2018 Nov 20.

Department of Stomatology (Endodontics section), School of Dentistry, University of Sevilla, C/ Avicena s/n, 41009, Sevilla, Spain. Electronic address:

Introduction: To investigate the physiological function of leptin in human dental pulp, and to determine the specific pathways implicated in its effect.

Methods: Twenty-seven dental pulp samples were obtained from human third molars. Pulp samples were treated with or without human recombinant leptin. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.019DOI Listing
February 2019
2 Reads

Improving the quality of data presentation in health sciences.

Arch Oral Biol 2019 Feb 16;98:123-125. Epub 2018 Nov 16.

Department of Pharmaceutical Sciences, Federal University of São Paulo (UNIFESP), Brazil.

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.016DOI Listing
February 2019
1 Read

Corrigendum to "MMP-3 and MMP-8 in rat mandibular condylar cartilage associated with dietary loading, estrogen level, and aging" [Arch. Oral Biol. 97 (2019) 238-244].

Arch Oral Biol 2019 02 22;98:122. Epub 2018 Nov 22.

Research Unit of Oral Health Sciences, University of Oulu, Oulu, Finland; Medical Research Center, Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.014DOI Listing
February 2019
2 Reads