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    8875 results match your criteria Archives of Oral Biology[Journal]

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    Evaluation of tooth root surface area using a three-dimensional scanning technique and cone beam computed tomographic reconstruction in vitro.
    Arch Oral Biol 2017 Jul 21;84:13-18. Epub 2017 Jul 21.
    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:
    Objective: To study the feasibility of measuring root surface area (RSA) by 3D scanning technique and cone beam computed tomography (CBCT) reconstruction in vitro.

    Design: Twenty extracted teeth (10 single-rooted teeth and 10 multi-rooted teeth) were collected in this study. The RSA of the extracted teeth was measured by the membrane technique, 3D scanning technique, and CBCT reconstruction. Read More

    Chronic high-protein diet induces oxidative stress and alters the salivary gland function in rats.
    Arch Oral Biol 2017 Sep 10;84:6-12. Epub 2017 Sep 10.
    Department of Restorative Dentistry, Waszyngtona 15 Str., Medical University Bialystok, Bialystok, Poland. Electronic address:
    Objective: Chronic high protein intake leads to an increase in reactive oxygen species (ROS) generation. However, there is no data on the impact of high-protein diet on the antioxidant barrier, oxidative stress and secretory function in the salivary glands of healthy individuals.

    Design: 16 male Wistar rats were randomly divided into 2 groups (n=8): normal protein (C) and high-protein diet (HP) for 8 weeks. Read More


    Cytotoxicity and potential anti-inflammatory activity of velutin on RAW 264.7 cell line differentiation: Implications in periodontal bone loss.
    Arch Oral Biol 2017 Sep 2;83:348-356. Epub 2017 Sep 2.
    Department of Clinical Sciences, Faculty of Dentistry, University of Toronto, Toronto, Canada. Electronic address:
    Objectives: Hypoxia-inducible factor-1α (HIF-1α) has been implicated in periodontal tissue inflammation and possibly in osteoclast differentiation, while polyphenols are known to be anti-inflammatory natural compounds that are capable of regulating the NF-κB protein complex pathway. The objective of this study was to investigate cytotoxicity and HIF-1α expression through the NF-κB pathway by polyphenol velutin (Euterpe oleracea Mart.), found in the pulp of acai fruit, during inflammatory RAW 264. Read More

    Difference in glycogen metabolism (glycogen synthesis and glycolysis) between normal and dysplastic/malignant oral epithelium.
    Arch Oral Biol 2017 Sep 2;83:340-347. Epub 2017 Sep 2.
    Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.
    Background: The purpose of this study was to investigate a difference in glycogen metabolism (glycogen synthesis and glycolysis) between the iodine stained (normal non-keartinized) and the unstained (dysplasctic/malignant) oral epithelium.

    Methods: Twenty-one frozen tissue samples of iodine-stained and unstained mucosal tissue were obtained from 21 OSCC patients. Serial frozen sections were cut and examined with the hematoxylin-eosin and periodic acid-Schiff methods and immunohistochemical (IHC) staining for Ki67, P53, molecules associated with glycogenesis (i. Read More

    Human papillomavirus infection in oral potentially malignant disorders and cancer.
    Arch Oral Biol 2017 Aug 26;83:334-339. Epub 2017 Aug 26.
    Department of Prosthodontics, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, People's Republic of China. Electronic address:
    Human papillomavirus (HPV) infects keratinocytes in the mucosa or skin, and persistent infection with HPV may lead to premalignant lesions and invasive cancer, especially cervical cancer. It has also been hypothesized that HPV infection is an etiological factor of oral squamous cell carcinoma and oral precancerous disorders such as lichen planus, leukoplakia, and erythroplakia. A high percentage of HPV in oral lesions supports the possible viral contribution, but an association of HPV infection with these lesions remains to be established. Read More

    Human pulpal blood flow in different root formation stages measured with transmitted-light plethysmography.
    Arch Oral Biol 2017 Aug 25;83:327-333. Epub 2017 Aug 25.
    Department of Pediatric Dentistry, Division of Oral Health Science, Graduate School, Tokyo Medical and Dental University, Japan.
    Objectives: To determine the pulp vitality after traumatic injury, dentists often use pulp sensitivity tests, which can be ambiguous in young permanent teeth with incomplete root formation. Transmitted-light plethysmography (TLP) is a non-invasive objective method that uses a 525-nm LED to detect blood volume change in the pulp. The present study aimed (1) to investigate pulpal blood flow with TLP and optical characteristics in healthy permanent maxillary incisors in different root formation stages, and (2) to assess the influences of body growth of the children and tooth color on the TLP amplitude. Read More

    Effects of dexamethasone and nimesulide on bisphosphonate-related osteonecrosis of the jaw: An experimental study.
    Arch Oral Biol 2017 Aug 30;83:317-326. Epub 2017 Aug 30.
    Department of Dental Clinic, Stomatology and Oral Pathology Sector, Federal University of Ceará, Fortaleza, Brazil.
    Objective: To evaluate the effects of dexamethasone (DEX) and nimesulide (NIM) on Bisphosphonate-related Osteonecrosis of the Jaw (BRONJ) in rats.

    Design: BRONJ was induced by zoledronic acid (ZA) infusion (0.2mg/kg) in Wistar rats (n=8), followed by extraction of the left lower first molar (BRONJ groups). Read More

    Observations on fluid flow from exposed dentine in primary teeth: An in vitro study.
    Arch Oral Biol 2017 Aug 25;83:312-316. Epub 2017 Aug 25.
    School of Physiology and Pharmacology, University of Bristol, University Walk, Bristol B58 1TD, United Kingdom. Electronic address:
    Objective: To investigate fluid flow through dentine in primary teeth in vitro using the replica technique, and to compare the results with those obtained from permanent dentine.

    Design: The experiments were carried out on 22 extracted, mandibular, primary, incisor teeth. The incisal edge was removed to 1mm below the dentino-enamel junction and half the exposed surface etched with phosphoric acid. Read More

    Adiponectin prevents orthodontic tooth movement in rats.
    Arch Oral Biol 2017 Aug 26;83:304-311. Epub 2017 Aug 26.
    Department of Biomaterials, Institute for Clinical Dentistry, University of Oslo, Oslo, Norway. Electronic address:
    Objective: The objective was to examine the effects of repetitive local administration of adiponectin on experimental tooth movement in rats.

    Materials And Methods: The maxillary right first molar of male Wistar rats (n=24) was moved mesially for 14days, with local adiponectin injections (0.2 or 2μg) every third day. Read More

    Mechanisms involved in facial heat hyperalgesia induced by endothelin-1 in female rats.
    Arch Oral Biol 2017 Aug 30;83:297-303. Epub 2017 Aug 30.
    Department of Pharmacology, Federal University of Parana, Curitiba, PR, Brazil. Electronic address:
    Objective: Pronociceptive responses to endothelins in the trigeminal system seem to be mediated by ETA and ETB receptors, which have been shown to be expressed in neurons of the trigeminal ganglion of humans and rats. The present study aimed to evaluate the ability of endothelin-1 (ET-1) to induce facial heat hyperalgesia in female rats, the contribution of ETA and ETB receptors to this response, as well as the mechanisms underlying heat hyperalgesia induced by ET-1.

    Design: ET-1 (100pmol/50μL) was injected into the upper lip and heat hyperalgesia was evaluated for up to 6h. Read More

    Is it really penetration? Locomotion of devitalized Enterococcus faecalis cells within dentinal tubules of bovine teeth.
    Arch Oral Biol 2017 Aug 25;83:289-296. Epub 2017 Aug 25.
    Clinic of Operative Dentistry, Medical Faculty Carl Gustav Carus, TU Dresden, Fetscherstr. 74, D-01307 Dresden, Germany.
    Objective: The aim of the present study was to evaluate the penetration characteristics of devitalized and vital E. faecalis cells into root dentinal tubules.

    Design: Thirteen root canals were incubated with devitalized (4days, 7days, 14days, 28days) and vital (28days) E. Read More

    Quantitative assessment of salivary oral bacteria according to the severity of dental caries in childhood.
    Arch Oral Biol 2017 Aug 16;83:282-288. Epub 2017 Aug 16.
    São Paulo State University (UNESP), School of Dentistry, Araçatuba, Department of Pediatric Dentistry and Public Health, Araçatuba, SP, Brazil. Electronic address:
    This study aimed to assess differences in selected oral bacteria in children according to the severity of dental caries. One hundred and thirty-six children, 36-60 months old were divided into three groups according to caries status: caries-free (CF) (n=47), early childhood caries (ECC) (n=40) and severe-early childhood caries (S-ECC) (n=49). Saliva was collected for detection and quantification of selected oral streptococci, Actinomyces naeslundii, Lactobacillus spp. Read More

    Structural, mechanical and chemical evaluation of molar-incisor hypomineralization-affected enamel: A systematic review.
    Arch Oral Biol 2017 Aug 19;83:272-281. Epub 2017 Aug 19.
    Department of Operative and Preventive Dentistry, Charité - Universitätsmedizin Berlin, Aßmannshauser Str. 4-6, 14197 Berlin, Germany.
    Objectives: To systematically assess and contrast reported differences in microstructure, mineral density, mechanical and chemical properties between molar-incisor-hypomineralization-affected (MIH) enamel and unaffected enamel.

    Methods: Studies on extracted human teeth, clinically diagnosed with MIH, reporting on the microstructure, mechanical properties or the chemical composition and comparing them to unaffected enamel were reviewed. Electronic databases (PubMed, Embase and Google Scholar) were screened; hand searches and cross-referencing were also performed. Read More

    Relatively low invasive capacity of Porphyromonas gingivalis strains into human gingival fibroblasts in vitro.
    Arch Oral Biol 2017 Aug 16;83:265-271. Epub 2017 Aug 16.
    Department of Periodontics, Institute of Oral Health Science, Ajou University School of Medicine, Suwon, South Korea. Electronic address:
    Objective: Bacterial invasion into host cells is a common strategy to escape the host immune system. Gingival fibroblasts (GFs) are the most predominant non-phagocytic cell type in gingival connective tissue. Therefore, invasion into GFs was thought to be the first strategy for the survival of Porphyromonas gingivalis. Read More

    "Metabolism of Odontoblast-like cells submitted to transdentinal irradiation with blue and red LED".
    Arch Oral Biol 2017 Aug 17;83:258-264. Epub 2017 Aug 17.
    Department of Orthodontics and Pediatric Dentistry, Araraquara School of Dentistry, São Paulo State University, Rua Humaitá, 1680, Araraquara, SP, Brazil.
    Objectives: The present study evaluated the trans-dentinal effect of light emitting diodes (LEDs) irradiation on the metabolism of odontoblast-like cells.

    Methods: Seventy-two dentin discs (0.2mm thick) were obtained from human molar teeth. Read More

    Effect of different dental burs for experimental induction of pulpitis in mice.
    Arch Oral Biol 2017 Aug 11;83:252-257. Epub 2017 Aug 11.
    Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address:
    Objective: To evaluate the effect of using different dental burs on the development of pulpal inflammation after pulpal exposure in mice.

    Design: Eighty-eight C57BL/6 mice were randomly assigned to group A (n=40), group B (n=40) and control group (n=8). The pulps of the maxillary first molars were occlusally exposed using ¼ round burs and polishing burs in group A and B respectively. Read More

    Amelogenin induces M2 macrophage polarisation via PGE2/cAMP signalling pathway.
    Arch Oral Biol 2017 Aug 12;83:241-251. Epub 2017 Aug 12.
    Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.
    Objectives: Amelogenin, the major component of the enamel matrix derivative (EMD), has been suggested as a bioactive candidate for periodontal regeneration. Apart from producing a regenerative effect on periodontal tissues, amelogenin has also been reported to have an anti-inflammatory effect. However, the precise molecular mechanisms underlying these effects remain unclear. Read More

    Effect of application sequence of fluoride and CPP-ACP on remineralization of white spot lesions in primary teeth: An in-vitro study.
    Arch Oral Biol 2017 Aug 10;83:236-240. Epub 2017 Aug 10.
    Department of Preventive Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, PO Box 3030, Irbid 22110, Jordan. Electronic address:
    Objective: To explore how application sequence of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride influences remineralization of enamel white spot lesions (WSL) in primary teeth.

    Design: In this in-vitro study, artificial WSLs were created in 130 primary teeth. Teeth were divided into 4 groups (n=27) and a control group (n=22) and exposed to one of the following remineralization regimens for 10 weeks: Group-1; 500ppm fluoride dentifrice; Group-2; 10% w/v CPP-ACP; Group-3; fluoride applied first, then CPP-ACP; Group-4; CPP-ACP applied first, then fluoride, and Group-5 was control. Read More

    Diabetes increases interleukin-17 levels in periapical, hepatic, and renal tissues in rats.
    Arch Oral Biol 2017 Aug 2;83:230-235. Epub 2017 Aug 2.
    Department of Endodontics, São Paulo State University (Unesp), School of Dentistry, Araçatuba, Rua José Bonifácio, 1193, Araçatuba, 16015-050, São Paulo, Brazil. Electronic address:
    Objectives: This study aimed to evaluate the association between endodontic infection and diabetes on interleukin-17 levels in periapical, hepatic, and renal tissues of rats.

    Design: Forty male rats were divided into groups: normoglycemic rats (N), normoglycemic rats with apical periodontitis (N-AP), rats with experimental diabetes (ED), and rats with experimental diabetes and apical periodontitis (ED-AP). Diabetes was induced by intravenous streptozotocin injection, and blood sugar levels were monitored to confirm disease development. Read More

    Histochemical and immunohistochemical examination of odontoblasts (petroblasts) in petrodentine formation of lungfish.
    Arch Oral Biol 2017 Aug 3;83:222-229. Epub 2017 Aug 3.
    Department of Histology, School of Life Dentistry at Niigata, The Nippon Dental University, Niigata, Japan.
    Objective: Petrodentine, the core of the lungfish tooth plate, is a well-mineralized tissue similar to mammalian enamel and analogous to enameloid in fish teeth. Petrodentine is formed solely by petroblasts, which are specialized odontoblasts, whereas enameloid is a composite tissue produced by both odontoblasts and dental epithelial cells. To clarify the details of petrodentine formation, petroblasts were investigated using histochemical and immunohistochemical techniques. Read More

    Mineralization-defects are comparable in fluorotic impacted human teeth and fluorotic mouse incisors.
    Arch Oral Biol 2017 Jul 29;83:214-221. Epub 2017 Jul 29.
    Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam, University of Amsterdam, and MOVE Research Institute, VU University Amsterdam, Amsterdam, Netherlands.
    Objective: Fluoride excess of 0.05-0.07mgF/kgbw/day in water or food additives like salt is the principal cause of endemic dental fluorosis. Read More

    Soft-diet feeding impairs neural transmission between mitral cells and interneurons in the mouse olfactory bulb.
    Arch Oral Biol 2017 Jul 29;83:209-213. Epub 2017 Jul 29.
    Department of Sensory Physiology, Asahikawa Medical University, 078-8510 Asahikawa, Japan. Electronic address:
    (Objective) The subventricular zone in mice generates a lot of neuroblasts even during adulthood. These neuroblasts migrate to the olfactory bulb and differentiate into inhibitory interneurons such as granule cells and periglomerular cells. Olfactory sensory neurons receive information from various odorants and transmit it to the olfactory bulb. Read More

    A novel method for sex estimation using 3D computed tomography models of tooth roots: A volumetric analysis.
    Arch Oral Biol 2017 Aug 4;83:202-208. Epub 2017 Aug 4.
    Edinburgh Unit for Forensic Anthropology, School of History Classics and Archaeology, University of Edinburgh, 4 Teviot place, EH8 9AG, Edinburgh, UK; Department of Medical Imaging, University Hospital of Heraklion, Heraklion, Crete 71110, Greece.
    Advances in technologies such as computed tomography (CT) scanning have allowed for further examination of dental sexual dimorphism in modern and archaeological populations. Read More

    A review of in-vitro fibrocartilage tissue engineered therapies with a focus on the temporomandibular joint.
    Arch Oral Biol 2017 Jul 23;83:193-201. Epub 2017 Jul 23.
    Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA 15260, United States; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, United States; Center for Craniofacial Regeneration, University of Pittsburgh, Pittsburgh, PA 15260, United States; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15260, United States. Electronic address:
    The inability of fibrocartilage, specifically the temporomandibular joint (TMJ) disc, to regenerate and remodel following injury presents a unique problem for clinicians. Tissue engineering then offers a potential regenerative therapy. In vitro testing provides a valuable screening tool for potential tissue engineered solutions. Read More

    A meta-analysis of randomized trials assessing the effects of probiotic preparations on oral candidiasis in the elderly.
    Arch Oral Biol 2017 Apr 30;83:187-192. Epub 2017 Apr 30.
    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
    Objective: Oral candidiasis is the most common fungal infection and can be attributed in part to dysbiosis, an imbalance in the resident oral microflora. Therefore, probiotics, which counter pathogenic microorganisms through competitive, antagonistic, and immunological effects, have been used by some clinicians. To date, the effect of probiotics in preventing oral candidiasis in the elderly is controversial. Read More

    Extracellular HSP72 induces proinflammatory cytokines in human periodontal ligament fibroblast cells through the TLR4/NFκB pathway in vitro.
    Arch Oral Biol 2017 Jul 30;83:181-186. Epub 2017 Jul 30.
    Department of Orthodontics, School of Dental Medicine, Tsurumi University, Yokohama, Japan.
    Objective: The aim of the present study was to examine the effect of extracellular heat shock protein (HSP) 72 on human periodontal ligament fibroblast cells (hPDLFs) in vitro.

    Design: hPDLFs were stimulated by recombinant human HSP72 (rhHSP72). TAK-242 was used to inhibit toll-like receptor 4 (TLR4) activity. Read More

    Characterization of the clustered regularly interspaced short palindromic repeats sites in Streptococcus mutans isolated from early childhood caries patients.
    Arch Oral Biol 2017 Jul 29;83:174-180. Epub 2017 Jul 29.
    State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:
    Objective: The aim of this study was to analyze the characteristics of the clustered regularly interspaced short palindromic repeats (CRISPR) sites in 45 clinical Streptococcus mutans strains and their relationship to the clinical manifestations of early childhood caries (ECC).

    Methods: Forty-five S. mutans strains were isolated from the plaque samples taken from sixty-three children. Read More

    Salivary microbiome in non-oral disease: A summary of evidence and commentary.
    Arch Oral Biol 2017 Jul 29;83:169-173. Epub 2017 Jul 29.
    Faculty of Dentistry, The University of Hong Kong, Hong Kong Special Administrative Region. Electronic address:
    Objective: The advent of high-throughput sequencing and 'omic' technologies is facilitating an 'open-ended' understanding of the human microbial community and its interplay with health. This commentary aims to present key perspectives and summarize current evidence from metagenomic studies of salivary microbiota in relation to general health and systemic diseases.

    Design: A narrative review of studies that described salivary microbiome composition in relation to various general health conditions was conducted and the main results were summarized. Read More

    Relationships between chewing rate, occlusion, cephalometric anatomy, muscle activity, and masticatory performance.
    Arch Oral Biol 2017 Jul 29;83:161-168. Epub 2017 Jul 29.
    Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48109-1078, USA. Electronic address:
    Objective: Mastication consists of rhythmic jaw openings and closings. Recent studies suggest that muscle mechanical properties determine the rhythmic rate; however, speed-accuracy tradeoffs may also play a role. This study evaluated how variation in chewing rate affected chewing performance, how masticatory muscle activity varied with chewing rate, and whether morphology and demographics contributed to performance. Read More

    Influences of microgap and micromotion of implant-abutment interface on marginal bone loss around implant neck.
    Arch Oral Biol 2017 Jul 29;83:153-160. Epub 2017 Jul 29.
    Department of Prosthodontics, School of Stomatology, Wuhan University, Wuhan, 430079, China. Electronic address:
    Objective: To review the influences and clinical implications of micro-gap and micro-motion of implant-abutment interface on marginal bone loss around the neck of implant.

    Design: Literatures were searched based on the following Keywords: implant-abutment interface/implant-abutment connection/implant-abutment conjunction, microgap, micromotion/micromovement, microleakage, and current control methods available. The papers were then screened through titles, abstracts, and full texts. Read More

    Microbiome of peri-implantitis affected and healthy dental sites in patients with a history of chronic periodontitis.
    Arch Oral Biol 2017 Jul 13;83:145-152. Epub 2017 Jul 13.
    Oral Sciences Research Group, Dental School, University of Glasgow, Glasgow, UK. Electronic address:
    Objective: To determine the composition of the microbiome of peri-implantitis sites and corresponding dental sites in subjects with a history of chronic periodontitis.

    Design: Clinical and radiographic examination assessed the periodontal/peri-implant disease status. Plaque samples were collected from one diseased implant with peri-implantitis, functional for at least two years and healthy sites in ten non-smokers who had received periodontal treatment prior to implant placement. Read More

    Expression of C-X-C motif chemokine receptors 4 and 7 in salivary gland neoplasms.
    Arch Oral Biol 2017 Jul 26;83:136-144. Epub 2017 Jul 26.
    Department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University, Henri-Dunant Road, Pathumwan, Bangkok, 10330, Thailand. Electronic address:
    Objectives: Chemokine receptors have been shown to overexpress in several cancer types. Binding of chemokines to their cognate chemokine receptors on tumor cells can promote tumor growth, angiogenesis and metastasis. The purposes of this study was to examine the expression of chemokine receptors, CXCR4 and CXCR7, in salivary gland neoplasms and its association with pathologic characteristics. Read More

    Effects of prostaglandin E2 on clonogenicity, proliferation and expression of pluripotent markers in human periodontal ligament cells.
    Arch Oral Biol 2017 Jul 25;83:130-135. Epub 2017 Jul 25.
    Center of Excellence in Oral and Maxillofacial Biology, Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand. Electronic address:
    Background And Objective: Based on our earlier work on the response of periodontal ligament (PDL) cells to mechanical stress by induction of cyclooxygenase expression and production of prostaglandin PGE2 that could regulate mineralization of PDL cells, it was hypothesized that PGE2 had potential effects on PDL stemness. In this study, we aimed to investigate clonogenicity, proliferation and expression of certain pluripotent markers, considered to be characteristics of PDL stemness, in response to treatment with exogenously-added PGE2.

    Material And Methods: Human PDL cells were cultured and treated with various doses of PGE2, and the aforementioned characteristics of PDL stemness were analyzed. Read More

    An index for the evaluation of 3D masticatory cycles stability.
    Arch Oral Biol 2017 Jul 24;83:124-129. Epub 2017 Jul 24.
    Department of Biomedical Sciences for Health, Functional Anatomy Research Center (FARC), Università degli Studi di Milano, Milano, Italy. Electronic address:
    Objectives: To introduce an index (Masticatory Stability Index, MSI) to analyze the stability of chewing cycles in standardized conditions and test it in a group of patients with subclinical mild temporomandibular disorder (TMD).

    Design: 23 subjects with mild subacute TMD and 21 healthy subjects were involved; they all responded to a questionnaire about signs and symptoms of TMD (ProTMDmulti) and underwent a myofunctional orofacial evaluation with scores, using the protocol of orofacial myofunctional evaluation with scores (OMES). Their mandibular kinematics was assessed with a 3D motion capture system during deliberate unilateral gum chewing. Read More

    Validation study of a new method for sexual prediction based on CBCT analysis of maxillary sinus and mandibular canal.
    Arch Oral Biol 2017 Jul 21;83:118-123. Epub 2017 Jul 21.
    Department of Oral and Maxillofacial Radiology, Academic Centre for Dentistry Amsterdam (ACTA), 4N-51 Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, The Netherlands. Electronic address:
    Objective: The aim of this study was to evaluate the accuracy of two craniometric methods for sexual prediction (SP) using cone-beam computed tomography (CBCT) in the Dutch population and to construct a formula for each method and then the two combined.

    Design: One-hundred sixty CBCT images were selected from a Dutch database (80 males and 80 females). The images were analyzed by two examiners taking seven measurements in the maxillary sinus (MS) region (first method) and nine in the mandibular canal (MC) region (second method). Read More

    The effect of active components from citrus fruits on dentin MMPs.
    Arch Oral Biol 2017 Jul 20;83:111-117. Epub 2017 Jul 20.
    State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, Fourth Military Medical University, 145 West Changle Road, Xi'an, 710032, People's Republic of China. Electronic address:
    Objectives: This study was aimed to evaluate the anti-matrix metalloproteinases (MMPs) ability of active components from citrus fruits (hesperetin: Hst, hesperidin: Hsd and naringenin: Nge).

    Methods: Inactivation effects of citrus flavonoids (Hst, Hsd, Nge) at different concentrations on soluble collagenase were measured using a fluorometric assay. Matrix-bound endogenous MMPs activity was evaluated via dry mass loss and hydroxyproline (HYP) release of demineralized human dentin. Read More

    The influence of food consistency on chewing rate and muscular work.
    Arch Oral Biol 2017 Jul 20;83:105-110. Epub 2017 Jul 20.
    Department of Oral-Maxillofacial Surgery, Prosthodontics and Special Dental Care, University Medical Center Utrecht, PO Box 85.500, 3508 GA Utrecht, The Netherlands.
    Food properties influence the parameters of the masticatory process, such as jaw movement, muscle activity and chewing rate. Firm foods will require more muscle activity than softer foods. However, the influence of food hardness on chewing rate is ambiguous as both slower and higher chewing rates have been reported for harder foods. Read More

    Effect of cinnamon (Cinnamomum verum) bark essential oil on the halitosis-associated bacterium Solobacterium moorei and in vitro cytotoxicity.
    Arch Oral Biol 2017 Jul 12;83:97-104. Epub 2017 Jul 12.
    Oral Ecology Research Group, Faculty of Dentistry, Université Laval, Quebec City, Quebec, Canada. Electronic address:
    Objectives: Halitosis, also known as bad breath or oral malodour, is a condition affecting a large proportion of the population. Solobacterium moorei is a Gram-positive anaerobic bacterium that has been specifically associated with halitosis. In this study, we investigated the effects of essential oils, more particularly cinnamon bark oil, on growth, biofilm formation, eradication and killing, as well as hydrogen sulfide (H2S) production by S. Read More

    MicroRNA-27b inhibits cell proliferation in oral squamous cell carcinoma by targeting FZD7 and Wnt signaling pathway.
    Arch Oral Biol 2017 Jul 15;83:92-96. Epub 2017 Jul 15.
    Department of Stomatology, Jinling Hospital, Nanjing 210009, Jiangsu, China. Electronic address:
    This study intended to investigate the role of microRNA-27b (miR-27b) in proliferation of oral squamous cell carcinoma (OSCC) cells and to explore the potential molecular mechanism. Cell proliferation was detected by MTT assay. The expression levels of miR-27b, Frizzled7 (FZD7), cyclin D1 and c-myc were detected by quantitative real time polymerase chain reaction (qRT-PCR). Read More

    Expression of planar cell polarity genes during mouse tooth development.
    Arch Oral Biol 2017 Jul 14;83:85-91. Epub 2017 Jul 14.
    Maxillofacial Anatomy, Department of Maxillofacial Biology, Graduate School, Tokyo Medical and Dental University, Tokyo 113-8549, Japan.
    Objective: Planar cell polarity (PCP) refers to the cell polarity across the tissue plane and controls various cell behaviors and structures. Although the expression of several PCP signaling components has been detected in tooth germs, knowledge of the gene expression patterns of these PCP components during tooth development remains incomplete. The aim of this study is to characterize the temporal and spatial changes in PCP gene expression during tooth development. Read More

    Intermittent administration of parathyroid hormone ameliorated alveolar bone loss in experimental periodontitis in streptozotocin-induced diabetic rats.
    Arch Oral Biol 2017 Jul 5;83:76-84. Epub 2017 Jul 5.
    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:
    Objective: Intermittent administration of parathyroid hormone (PTH) has been demonstrated to have anabolic effects on bone metabolism and is approved for use in the treatment of osteoporosis. This study evaluates the role of intermittent PTH administration on alveolar bone loss in streptozotocin (STZ)-induced diabetic rats.

    Design: Fifty male Sprague Dawley rats were randomly divided into the following five groups: (1) a control group (saline placebo without ligature and STZ injection), (2) a PTH group (PTH administration without ligature and STZ injection), (3) an L group (saline placebo with ligature), (4) an L+STZ group (saline placebo with ligature and STZ injection), and (5) an L+STZ+PTH group (PTH administration with ligature and STZ injection). Read More

    In silico search of inhibitors of Streptococcus mutans for the control of dental plaque.
    Arch Oral Biol 2017 Jul 1;83:68-75. Epub 2017 Jul 1.
    Programa de Estudio y Control de Enfermedades Tropicales-PECET, Facultad de Medicina, Universidad de Antioquia, SIU- Sede de Investigación Universitaria, Medellín, Colombia. Electronic address:
    Biofilm is an extremely complex microbial community arranged in a matrix of polysaccharides and attached to a substrate. Its development is crucial in the pathophysiology of oral infections like dental caries, as well as in periodontal, pulp, and periapical diseases. Streptococcus mutans is one of the most effective microorganisms in lactic acid production of the dental biofilm. Read More

    Expression of MyHC isoforms mRNA transcripts in different regions of the masseter and medial pterygoid muscles in chimpanzees.
    Arch Oral Biol 2017 Jul 9;83:63-67. Epub 2017 Jul 9.
    Unit of Human Anatomy and Embryology, University of Barcelona, C/Casanova 143, 08036 Barcelona, Spain.
    Objective: The aim of this study is to examine the expression pattern of the different myosin heavy chain (MyHC) isoforms in the masseter and medial pterygoid muscles by real time quantitative polymerase chain reaction (RT-qPCR) to obtain information at molecular level which can be related to the functional characteristics of these two muscles.

    Design: The masseter, deep and superficial portion, and medial pterygoid muscles of five adult Pan troglodytes were dissected in order to obtain samples of the anterior and posterior regions of each portion of the masseter and of the medial pterygoid. The expression of MyHC isoforms mRNA transcripts was analyzed by RT-qPCR. Read More

    Immunohistochemical investigations on the expression of programmed cell death ligand 1, human leukocyte antigens G and E, and granzyme B in intraoral mucoepidermoid carcinoma.
    Arch Oral Biol 2017 Jul 8;83:55-62. Epub 2017 Jul 8.
    Federal University of Goiás, Faculty of Dentistry, Department of Stomatology (Oral Pathology), Goiânia, Brazil. Electronic address:
    Objective: To identify the expression of nonclassical human leukocyte antigen G and E (HLA-G and -E), programmed cell death ligand-1 (PD-L1) and granzyme B (GB) in intraoral mucoepidermoid carcinomas (MECs), and to assess whether such expressions are related to metastasis, survival, staging, tumor grade and number of GB-positive cells.

    Design: For this cross-sectional study, samples of MEC (n=30) were selected and classified as low-grade (LG), intermediate-grade (IG) or high-grade (HG), according to the WHO grading system. HLA-G, -E and PD-L1 were identified by immunohistochemistry and quantified as the proportion of positive neoplastic cells. Read More

    Gingival crevicular fluid and plasma oxidative stress markers and TGM-2 levels in chronic periodontitis.
    Arch Oral Biol 2017 Jun 29;83:47-54. Epub 2017 Jun 29.
    Ege University, School of Dentistry, Department of Periodontology, İzmir, Turkey.
    Objective: This study was aimed to evaluate the gingival crevicular fluid (GCF) and plasma transglutaminase-2 (TGM-2), total antioxidant capacity (TAC), total oxidant status (TOS), ferric reducing antioxidant power (FRAP) and thiobarbituric acid reactive substances (TBARS) in patients with chronic periodontal disease.

    Materials And Methods: Twenty patients with chronic periodontitis (CP), 20 patients with gingivitis and 20 healthy subjects were enrolled in the study. Clinical periodontal parameters including probing depth, clinical attachment level, plaque index and papillary bleeding index were recorded. Read More

    Influence of the RPL34 gene on the growth and metastasis of oral squamous cell carcinoma cells.
    Arch Oral Biol 2017 Jun 30;83:40-46. Epub 2017 Jun 30.
    Department of Stomatology, Jingzhou Central Hospital, The Second Clinical Medical College, Yangtze University, Jingzhou 434000, Hubei Province, PR China.
    Background: Oral squamous cell carcinoma (OSCC) accounts for almost 3% of all malignant tumors all over the world. This study aims to investigate the correlation of RPL34 with the cell growth and metastasis of oral squamous cell carcinoma (OSCC) as well as its clinical prognosis.

    Method: Quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemistry were conducted to determine the RPL34 expression in 85 OSCC tissues and 30 normal oral mucosa tissues. Read More

    Effects of melatonin on the proliferation and differentiation of human dental pulp cells.
    Arch Oral Biol 2017 Jun 30;83:33-39. Epub 2017 Jun 30.
    Department of Pediatric Dentistry, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China. Electronic address:
    Objective: Effects of melatonin on the proliferation and differentiation of human dental pulp cells (hDPCs) remain unclear. The purpose of this study was to investigate the effect of melatonin on the proliferation and differentiation of the hDPCs.

    Design: Primary hDPCs were obtained from the third molar of volunteer aged from 18 to 25. Read More

    Sleep bruxism and related risk factors in adults: A systematic literature review.
    Arch Oral Biol 2017 Jul 5;83:25-32. Epub 2017 Jul 5.
    Department of Surgical Sciences, Specialization School of Orthodontics, Dental School, University of Torino, Via Nizza 230, 10126 Torino, Italy; Department of Surgical Sciences, Gnathology Unit, Dental School, University of Torino, Via Nizza 230, 10126 Torino, Italy.
    Objective: The aim of this article was to systematically review the literature to assess the relationship between risk factors and sleep bruxism (SB) in adults (age ≥18 years).

    Design: A systematic search of the following databases was carried out: PubMed, Embase, Scopus, Cochrane Oral Health Group's Trial Register and Cochrane Register of Controlled Trials, Web of Science, LILACs and SciELO. Nine out of the 4583 initially identified articles were selected. Read More

    Pathogenicity and genetic profile of oral Porphyromonas species from canine periodontitis.
    Arch Oral Biol 2017 Jul 4;83:20-24. Epub 2017 Jul 4.
    Anaerobe Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo - USP, Sao Paulo, SP, Brazil. Electronic address:
    Objective: In this study, the presence of the prtC and fimA genes involved in the pathogenicity of oral Porphyromonas spp. isolated from dogs with periodontitis and healthy, as well as their genetic diversity was investigated.

    Design: Thirty-two Beagle dogs, 24 with periodontitis and 8 healthy were evaluated. Read More

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