2,262 results match your criteria Archives of Medical Science[Journal]


How does subchorionic hematoma in the first trimester affect pregnancy outcomes?

Arch Med Sci 2022 8;18(3):639-646. Epub 2021 Jan 8.

Department of Obstetrics and Gynecology, Medeniyet University Göztepe Training and Research Hospital, Istanbul, Turkey.

Introduction: Subchorionic hematoma (SCH) in pregnancy has been associated with increased risk of adverse pregnancy outcomes. We aimed to investigate the association of SCH with adverse pregnancy outcomes in pregnant women in relation to size of hematoma and control subjects.

Material And Methods: This study included 178 pregnant women with sono-graphically detected SCH in the 1 trimester, and 350 pregnant controls without SCH. Read More

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January 2021

Overlap between Sjogren's syndrome and anti-synthetase syndrome: association or coincidence?

Arch Med Sci 2022 20;18(3):820-821. Epub 2022 Apr 20.

Department of Rheumatology and Immunology, Zhuzhou Hospital Affiliated to Xiangya Medical College, Central South University, Zhuzhou, Hunan, China.

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Multiple endocrine neoplasia type 1 with ectopic parathyroid adenoma.

Arch Med Sci 2022 14;18(3):829-832. Epub 2022 Apr 14.

Department of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

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Two complications in patients with systemic lupus erythematosus: lupus cystitis and lupus enteritis.

Arch Med Sci 2022 20;18(3):822-824. Epub 2022 Apr 20.

Department of Rheumatology and Immunology, Zhuzhou Hospital Affiliated to Xiangya Medical College, Central South University, Zhuzhou, Hunan, China.

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An individualized algorithm to predict mortality in COVID-19 pneumonia: a machine learning based study.

Arch Med Sci 2022 14;18(3):587-595. Epub 2022 Jan 14.

Humanitas AI Center, Humanitas Research Hospital IRCCS, Milan, Italy.

Introduction: Identifying SARS-CoV-2 patients at higher risk of mortality is crucial in the management of a pandemic. Artificial intelligence techniques allow one to analyze large amounts of data to find hidden patterns. We aimed to develop and validate a mortality score at admission for COVID-19 based on high-level machine learning. Read More

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January 2022

5,7,2,5-tetrahydroxy-8,6-dimethoxyflavone up-regulates miR-145 expression and inhibits proliferation of gastric cancer cells.

Arch Med Sci 2022 13;18(3):753-760. Epub 2021 Apr 13.

Department of Oncology, Second People's Hospital of Dezhou, Decheng District, Dezhou, Shandong Province, China.

Introduction: Gastric cancer is a frequently detected malignancy, and its incidence has increased over the past decades in East Asia. The present study investigated the effect of 5,7,2, 5-tetrahydroxy-8,6-dimethoxyflavone (THDMF) on gastric cancer cells and explored the underlying mechanism. The study analysed cell viability changes, apoptotic features, and metastasis potential of treatment with THDMF. Read More

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Ibrutinib attenuated DSS-induced ulcerative colitis, oxidative stress, and the inflammatory cascade by modulating the PI3K/Akt and JNK/NF-κB pathways.

Arch Med Sci 2022 20;18(3):805-815. Epub 2022 Apr 20.

State Key Laboratory of Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School, Peking University, Shenzhen, China.

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Application of three-dimensional printing technology for spinal tuberculosis.

Arch Med Sci 2022 20;18(3):833-837. Epub 2022 Apr 20.

Department of Orthopedics, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing, China.

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Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors.

Arch Med Sci 2022 14;18(3):800-804. Epub 2022 Apr 14.

Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland.

Introduction: The objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors.

Methods: A total of 723 breast cancer patients, who had been diagnosed and treated during 2005-2019, were retrospectively reviewed. Patients > 65 years of age (92 patients) were compared with < 50-year-old women (306 patients). Read More

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Grisel syndrome and peripheral arthritis simultaneously occurred in a 7-year-old Chinese boy with Kawasaki disease.

Arch Med Sci 2022 20;18(3):816-819. Epub 2022 Apr 20.

Department of Pediatrics, the First Affiliated Hospital of Anhui Medical University, Hefei, China.

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Is cognitive ability a factor in explaining differences in physiological and psychological stress responses?

Authors:
Burcu Koksal

Arch Med Sci 2022 23;18(2):553-558. Epub 2022 Feb 23.

Department of Physiology, Lokman Hekim University, Çankaya, Ankara, Turkey.

Introduction: Determining differences and patterns in responses might help to understand over-excitability of students with high cognitive ability (SHCA) and to design treatments for helping them in controlling stress.

Methods: A comparative research method was used with three different instruments. The data were analyzed by -test and Welch's -test. Read More

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February 2022

Early identification of high-risk patients with recurrent acute pancreatitis progression to chronic pancreatitis.

Arch Med Sci 2022 6;18(2):535-539. Epub 2022 Feb 6.

Department of Gastroenterology, Peking University Third Hospital, Haidian District, Beijing, China.

Introduction: The aim of the study was to develop a simple tool for early identification of high-risk patients with recurrent acute pancreatitis (RAP) progression to chronic pancreatitis (CP) in primary hospitals or outpatient clinics.

Methods: This retrospective cohort study included 265 patients with RAP.

Results: A nomogram for RAP progression to CP was developed and the C-index of the model was 0. Read More

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February 2022

Type 2 diabetes control and complications and their relation to serum magnesium level.

Authors:
Khaled Alswat

Arch Med Sci 2022 18;18(2):307-313. Epub 2021 Mar 18.

Department of Medicine, Taif University, Taif, Saudi Arabia.

Introduction: Type 2 diabetes (T2D) is a growing health problem nationally and worldwide. Magnesium is an important mineral that is essential for a wide range of metabolic reactions. Here, our primary goal was to determine the prevalence of hypomagnesemia and its relationship to glycemic control, cardiovascular markers, and T2D-related complications. Read More

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Treatment adherence and effect of concurrent statin intensity on the efficacy and safety of alirocumab in a real-life setting: results from ODYSSEY APPRISE.

Arch Med Sci 2022 29;18(2):285-292. Epub 2021 Oct 29.

ECOGENE-21 and Clinical Lipidology Unit, Community Gene Medicine Center, Department of Medicine, Université de Montréal, Chicoutimi, QC, Canada.

Introduction: The phase IIIb open-label ODYSSEY APPRISE study prospectively assessed the safety and efficacy of alirocumab (a proprotein convertase subtilisin/kexin type 9 [PCSK9] inhibitor) in a real-life setting in high cardiovascular risk patients with heterozygous familial hypercholesterolemia or low-density lipoprotein cholesterol (LDL-C) not at goal despite maximally tolerated dose statins ± other lipid-lowering therapies (NCT02476006). This post-hoc analysis assessed patient adherence to statins and alirocumab, plus alirocumab efficacy and safety, according to concomitant statin intensity and prior ezetimibe usage.

Material And Methods: Patients received alirocumab 75 or 150 mg (dose adjustment based on physician's judgment) every 2 weeks (for ≥ 3 to ≤ 30 months). Read More

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October 2021

Omega-6 fatty acids and the risk of cardiovascular disease: insights from a systematic review and meta-analysis of randomized controlled trials and a Mendelian randomization study.

Arch Med Sci 2022 24;18(2):466-479. Epub 2021 Apr 24.

Department of Preventive Cardiology and Lipidology, Chair of Nephrology and Hypertension, Medical University of Lodz, Lodz, Poland.

Introduction: Omega-6 polyunsaturated fatty acids (PUFAs) represent almost 15% of the total energy intake in Western countries. Their effects on the cardiovascular (CV) risk factors are still controversial. Thus, we performed a systematic review and meta-analysis of randomized control trials (RCTs) as well as a Mendelian randomization (MR) analysis to evaluate the links and possible causality between supplementation or serum levels of omega-6 PUFA, CV disease (CVD) and cardiometabolic risk factors. Read More

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Eosinophilia in a patient with ankylosing spondylitis treated with prolonged adalimumab only.

Arch Med Sci 2022 23;18(2):564-567. Epub 2022 Feb 23.

Department of Rheumatism and Immunology, Ningbo No. 6 Hospital, Ningbo, China.

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February 2022

Association between myostatin serum concentration and body fat level in peri- and postmenopausal women.

Arch Med Sci 2022 19;18(2):365-375. Epub 2021 Mar 19.

Department of Human Physiology, Medical University of Lublin, Lublin, Poland.

Introduction: Every year over 25 million women worldwide experience menopause symptoms. Menopause leads to the occurrence and intensification of many psychological and somatic disorders including body composition change. Myostatin may play a crucial role in the remodeling of muscle and fat tissue. Read More

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A preliminary evaluation of oxidative stress in patients with gastric cancer before chemotherapy.

Arch Med Sci 2022 18;18(2):440-447. Epub 2021 Mar 18.

Department of Surgical Oncology, Medical University of Lodz, Copernicus Memorial Hospital of Lodz, Lodz, Poland.

Introduction: Due to an imbalanced redox status, cancer cells generate intrinsically higher levels of reactive oxygen species (ROS) compared to normal cells. Targeting ROS is an important therapeutic strategy for cancer as exemplified by cancer drugs, which induce ROS-dependent synergistic cytotoxicity in gastric cancer cells. The present study was designed to assess the level of selected oxidative stress biomarkers in blood plasma derived from gastric cancer patients. Read More

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Regional analysis of diabetic retinopathy and co-existing social and demographic factors in the overall population of Poland.

Arch Med Sci 2022 22;18(2):320-327. Epub 2021 May 22.

Department of Ophthalmology, Medical University of Warsaw, Public Ophthalmic Clinical Hospital (SPKSO), Warsaw, Poland.

Introduction: The aim of our study was to analyse the regional differences in diabetic retinopathy (DR) prevalence and its co-existing social and demographic factors in the overall population of Poland in the year 2017.

Material And Methods: Data from all levels of healthcare services at public and private institutions recorded in the National Health Fund database were evaluated. International Classification of Diseases codes were used to identify patients with type 1 and type 2 diabetes mellitus (DM) and with DR. Read More

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Antiarrhythmic effect of 9-week hybrid comprehensive telerehabilitation and its influence on cardiovascular mortality in long-term follow-up - subanalysis of the TELEREHabilitation in Heart Failure Patients randomized clinical trial.

Arch Med Sci 2022 22;18(2):293-306. Epub 2021 May 22.

Telecardiology Center, National Institute of Cardiology, Warsaw, Poland.

Introduction: Cardiac rehabilitation is a component of heart failure (HF) management, but its effect on ventricular arrhythmias is not well understood. We analyzed the antiarrhythmic effect of a 9-week hybrid comprehensive telerehabilitation (HCTR) program and its influence on long-term cardiovascular mortality in HF patients taken from the TELEREHabilitation in Heart Failure Patients (TELEREH-HF) trial.

Material And Methods: We evaluated the presence of non-sustained ventricular tachycardia (nsVT) and frequent premature ventricular complexes ≥ 10 beats/hour (PVCs ≥ 10) in 24-hour ECG monitoring at baseline and after 9-week HCTR or usual care (UC) of 773 HF patients (NYHA I-III, LVEF ≤ 40%). Read More

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Extraction of antibacterial peptides against from bovine milk casein.

Arch Med Sci 2022 24;18(2):376-381. Epub 2021 Mar 24.

School of Health Sciences, Macao Polytechnic Institute, Macao, China.

Introduction: More than half of the world's population is infected with , which may cause gastritis, peptic ulcer and even gastric cancer. The World Health Organization (WHO) has announced that infection is a class I carcinogen and hence eradication of it is highly important. Bovine milk contains caseins, which can be digested by various enzymes in the human stomach to produce antibacterial peptides. Read More

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Biochemical and cardiovascular predictors of PIMS-TS risk in children after COVID-19 recovery: preliminary results of the LATE-COVID-Kids Study.

Arch Med Sci 2022 23;18(2):545-552. Epub 2022 Feb 23.

Department of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Lodz, Poland.

Introduction: We aimed to characterize biochemical and cardiovascular predictors of the paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) risk based on the data from the LATE-COVID-Kids study.

Methods: 148 consecutive COVID-19 convalescents hospitalized for the clinical evaluation after the acute phase of COVID-19 were classified into two groups related to symptoms: 33 children finally diagnosed with PIMS-TS and 115 children without PIMS-TS (control group).

Results: PIMS-TS children were significantly younger (6. Read More

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February 2022

One case of papillary thyroid carcinoma complicated with epidermal follicular carcinoma was followed up for four years.

Arch Med Sci 2022 24;18(2):559-563. Epub 2022 Feb 24.

Department of Thyroid Surgery, Affiliated Hospital of Guizhou Medical University, China.

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February 2022

Presence of cell-free fetal circRNA in maternal plasma.

Arch Med Sci 2022 23;18(2):540-544. Epub 2022 Feb 23.

Department of Obstetrics, The First Afliated Hospital of Chongqing Medical University, Chongqing, China.

Introduction: There is an urgent need to find novel stable cell-free fetal (cff-) RNA in the maternal circulation to facilitate the advance of non-invasive prenatal testing (NIPT) to more effectively avoid birth defects.

Methods: CircRNA microarray was used to detect the cff-circRNA in plasma.

Results: There were cff-circRNAs from the fetus in the peripheral blood of pregnant women and they persisted even until at least 24 h after delivery. Read More

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February 2022

Sonographic measurement of the fetal pancreas in women with gestational diabetes.

Arch Med Sci 2022 4;18(2):382-387. Epub 2021 Aug 4.

Maccabi Health Services, Ultrasound Unit, The Negev Medical Center, Beer-Sheva, Israel.

Introduction: Maternal glycemic state is positively correlated with fetal insulin secretion. Randomized control studies have shown that treatment during pregnancy inhibits to some degree this glycemic effect. Our study aimed to assess fetal pancreas size in a population of treated mothers with gestational diabetes. Read More

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The UCA1 and microRNA-18a signaling pathway mediates the irisin-lowering effect of metformin in the management of polycystic ovary syndrome.

Arch Med Sci 2022 19;18(2):489-498. Epub 2021 Mar 19.

Department of Reproduction, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.

Introduction: The present study aimed to clarify the underlying mechanism of metformin (met) in the management of polycystic ovary syndrome (PCOS) and to explore the role of the UCA1/microRNA-18a signaling pathway in the control of PCOS.

Material And Methods: Real-time PCR was performed to compare the levels of irisin, blood glucose, UCA1 and miR-18a among PCOS, PCOS + Met, and control groups using area under curve (AUC) values. In-silicon analysis and luciferase assay were performed to explore the regulatory relationship among UCA1, miR-18a and irisin. Read More

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Clinical outcomes of patients with acute lymphoblastic leukemia receiving the hyper-CVAD regimen and assessment of the risk of hepatitis flares due to hepatitis B virus reactivation after chemotherapy.

Arch Med Sci 2022 19;18(1):121-128. Epub 2021 Mar 19.

Department of Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong.

Introduction: Hyper-CVAD (hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone) has become a popular regimen for adults with acute lymphoblastic leukemia (ALL). We assessed the efficacy and tolerability of hyper-CVAD in the treatment of adult ALL.

Material And Methods: We retrospectively reviewed ALL patients aged 18 or above receiving the hyper-CVAD regimen. Read More

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Diagnosis of adenoid cystic carcinoma in the breast: a case report and literature review.

Arch Med Sci 2022 14;18(1):279-283. Epub 2022 Jan 14.

Department of Pathology, The Affiliated Hospital of Chengde Medical College, Chengde, Hebei Province, China.

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January 2022