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    1753 results match your criteria Archives of Iranian medicine[Journal]

    1 OF 36

    Early Treatment Was Life Saving in Varicella Pneumonia of an Immunocompetent Adult.
    Arch Iran Med 2018 May 1;21(5):223-225. Epub 2018 May 1.
    Infectious Disease and Clinical Microbiology, Erzurum Region Training and Research Hospital, Erzurum, Turkey.
    Chickenpox, an infection of childhood with vesicular skin rash, is caused by varicella-zoster virus (VZV). Although the infection is rare in adults, it can cause serious complications Varicella pneumonia is the most encountered complication. In this report, a VZV pneumonia case in a previously healthy adult is presented. Read More

    Estimation and Prediction of Avoidable Health Care Costs of Cardiovascular Diseases and Type 2 Diabetes Through Adequate Dairy Food Consumption: A Systematic Review and Micro Simulation Modeling Study.
    Arch Iran Med 2018 May 1;21(5):213-222. Epub 2018 May 1.
    Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Iran.
    Background: Recent evidence from prospective cohort studies show a relationship between consumption of dairy foods and cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). This association highlights the importance of dairy foods consumption in prevention of these diseases and also reduction of associated healthcare costs. The aim of this study was to estimate avoidable healthcare costs of CVD and T2D through adequate dairy foods consumption in Iran. Read More

    The Prevalence of PCR-Confirmed Pertussis Cases in Palestine From Archived Nasopharyngeal Samples.
    Arch Iran Med 2018 May 1;21(5):208-212. Epub 2018 May 1.
    Department of Medical Lab sciences, Faculty of Allied Health sciences, Arab American University, Palestine.
    Background: Pertussis caused by Bordetella pertussis is a vaccine-preventable disease causing whooping cough in humans of all ages. This study reports infection rate of pertussis in Palestine between the years 2004-2008 from archived nasopharyngeal samples collected from clinically- suspected cases.

    Methods: A convenience archived DNA samples collected from 267 clinically-suspected pertussis cases were investigated for B. Read More

    Which Social Values Are Considered in Iranian Health System?
    Arch Iran Med 2018 May 1;21(5):199-207. Epub 2018 May 1.
    Vice-Chancellor's Office in Treatment Affairs, Health Economy, Standard and Health Technology Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Background: Health systems have a set of limited resources for meeting the needs of communities. Health priority setting based on criteria and values is inevitable in such situation. This paper aims to identify the social values that are considered in Iranian health system. Read More

    Candida albicans Release Intracellular Bacteria When Treated With Amphotericin B.
    Arch Iran Med 2018 May 1;21(5):191-198. Epub 2018 May 1.
    Department of Microbiology, Faculty of Biological Sciences and Technology, Shahid Beheshti University, Tehran, Iran.
    Background: Coexistence of bacteria and yeast in a myriad of microbial communities is indicative of their intimate relationship, which could be the intracellular existence of bacteria inside yeast. In this study, the intracellular existence of bacteria inside yeast and bacterial release from amphotericin B-treated yeasts was examined using polymerase chain reaction (PCR) and microscopy.

    Methods: Released bacteria, B1 from Y1 (a gastric yeast) and B2 from Y2 (an oral yeast) were identified as Staphylococcus hominis and Staphylococcus haemolyticus by biochemical tests as well as amplification of Staph-specific tuf and 16S rRNA genes. Read More

    The Significance of the Stromal Response in Breast Cancer: An Immunohistochemical Study of Myofibroblasts in Primary and Metastatic Breast Cancer.
    Arch Iran Med 2018 May 1;21(5):185-190. Epub 2018 May 1.
    Pathology and Stem Cells Research Center, Pathology Department, Afzalipour Kerman Medical Sciences University, Kerman, Iran.
    Background: Gene expression profiling of breast cancer has demonstrated the importance of stromal response in determining the prognosis of invasive breast cancer. The host response to breast cancer is of increasing interest to pathologists and may be a future focus for novel pharmacological treatments.

    Methods: This study describes the pattern of distribution of stromal myofibroblasts using immunostains for CD10 and smooth muscle actin (SMA) in 50 primary breast cancers and their matched nodal metastases (68. Read More

    Nodular Hepatic Tuberculosis Masquerading as a Seminoma Liver Metastasis.
    Arch Iran Med 2018 Apr 1;21(4):180-182. Epub 2018 Apr 1.
    Department of General Surgery, Habib Bourguiba Hospital of Sfax, Sfax, Tunisia.
    Isolated macro-nodular liver tuberculosis is a very rare condition. It may mimic primitive or secondary tumors of the liver. This could delay or mislead the therapeutic management. Read More

    Calpains: Diverse Functions but Enigmatic.
    Arch Iran Med 2018 Apr 1;21(4):170-179. Epub 2018 Apr 1.
    Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
    Calpains are a group of non-lysosomal Ca-dependent cysteine proteases with numerous substrates. Calpains have been identified in almost all eukaryotes and bacteria but not in archaebacteria. In the human genome, this group of enzymes has 15 isoforms and is present ubiquitously and demonstrates tissue-specific patterns of expression. Read More

    Causal Methods for Observational Research: A Primer.
    Arch Iran Med 2018 Apr 1;21(4):164-169. Epub 2018 Apr 1.
    Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    The goal of many observational studies is to estimate the causal effect of an exposure on an outcome after adjustment for confounders, but there are still some serious errors in adjusting confounders in clinical journals. Standard regression modeling (e.g. Read More

    Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy for Management of Peritoneal Carcinomatosis.
    Arch Iran Med 2018 Apr 1;21(4):158-163. Epub 2018 Apr 1.
    Department of Cardiac Surgery, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
    Background: Treatment of peritoneal metastases has gained interest among oncologic communities around the world. Cytoreductive surgery (CRS) and hyperthermic intraoperative chemotherapy (HIPEC) have come to be the treatment of choice for selected patients with peritoneal carcinomatosis (PC) in recent years. Prior to HIPEC, patients were treated with palliative support and only guaranteed a few months to live. Read More

    Utilization of SNAP II and SNAPPE II Scores for Predicting the Mortality Rate Among a Cohort of Iranian Newborns.
    Arch Iran Med 2018 Apr 1;21(4):153-157. Epub 2018 Apr 1.
    Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Background: The present study was conducted to determine the utility of Score for Neonatal Acute Physiology II (SNAP II) and Score for Neonatal Acute Physiology with Perinatal Extension II (SNAPPE II) scoring systems as predictors of neonatal mortality rate, and to compare the predictive value of these two methods.

    Methods: In this prospective study data were gathered from infants admitted to the neonatal intensive care unit (NICU) of Imam Hossein Medical Center, Tehran, Iran, from March 2015 to December 2015. In addition to demographic data, Apgar score at 5 minutes after birth, initial and final diagnosis, SNAP II, and SNAPPE II were recorded within 24 hours after admission to the NICU. Read More

    The Iranian Neonatal Registry: Primary Results.
    Arch Iran Med 2018 Apr 1;21(4):145-152. Epub 2018 Apr 1.
    Family Health Institute, Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.
    Background: Neonatal registry network systems are conducted worldwide in order to improve the quality of neonatal care and also to integrate research into daily practice.

    Methods: We designed a neonatal registry system and conducted a pilot study in Vali-Asr Hospital to explore its effectiveness to develop an overview of our neonatal status. This study is a report of three years of data registry (2013-2016) in above mentioned system. Read More

    Second National Integrated Micronutrient Survey in Iran: Study Design and Preliminary Findings.
    Arch Iran Med 2018 Apr 1;21(4):137-144. Epub 2018 Apr 1.
    School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
    Background: The main objective of the Second National Integrated Micronutrient Survey (NIMS-II) was to assess the nutritional status of four micronutrients, namely iron, zinc, and vitamins A and D, and also to conduct an anthropometric assessment of selected groups of children, adolescents, pregnant women, and adults, disaggregated by sex and residential area in nationally representative samples. This paper reports the design of the study along with preliminary findings.

    Methods: In this study, 32 770 individuals were selected by using single-stage cluster sampling. Read More

    Recurrent Pilonidal Sinus Cyst on Penis.
    Arch Iran Med 2018 Mar 1;21(3):131-133. Epub 2018 Mar 1.
    Department of General Surgery, Ministry of Health, Numune Teaching and Research Hospital, Adana, Turkey.
    Pilonidal sinus, including one or more sinus canals and hairs, is a disease with a chronic course showing acute attacks which is often encountered in the general population, usually affecting young adults, at a rate in males twice that of females. Pilonidal sinus on the penis is so rare that very few cases have been reported in literature. A 20-year-old male presented to the urology outpatient clinic with the complaint of a suppurative lesion with discharge on the skin of the penis which had been ongoing for approximately three months. Read More

    National and Subnational Cardiovascular Diseases Mortality Attributable to Salt Consumption in Iran by Sex and Age From 1990 to 2016.
    Arch Iran Med 2018 Mar 1;21(3):122-130. Epub 2018 Mar 1.
    Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
    Background: Dietary salt consumption is an important factor for mortality from cardiovascular diseases (CVDs). Therefore, the aim of this study is to measure the levels of salt consumption and then estimate the effects of current levels of salt consumption on mortality from CVDs at national and subnational levels from 1990 to 2016 in Iran.

    Methods: In this study, we will use national and subnational studies with data on salt consumption, including self-report or lab tests for sodium measurement and all available published data about salt and sodium (with conduct a systematic review) to estimate salt exposure levels. Read More

    Endovascular Procedures in Treatment of Infrapopliteal Arterial Occlusive Disease: Single Center Experience With 69 Infrapopliteal Procedures.
    Arch Iran Med 2018 Mar 1;21(3):118-121. Epub 2018 Mar 1.
    Department of Radiology, Clinical Centre of Vojvodina, University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
    Background: Peripheral arterial occlusive disease (PAD) includes acute and chronic disorders of the blood supply as a result of obstruction of blood flow in the arteries of the limb. Treatment of PAD can be conservative, surgical and endovascular. Percutaneous transluminal angioplasty with or without stenting has become a recognized method, which is increasingly used in treatment of arterial occlusive disease. Read More

    Eating Disorders Among Female Students of Taif University, Saudi Arabia.
    Arch Iran Med 2018 Mar 1;21(3):111-117. Epub 2018 Mar 1.
    Departments of Family and Community Medicine, College of Medicine and Applied Medical Sciences, Taif University, Saudi Arabia.
    Background: Eating disorders are a common health problem among adolescents, and females are especially vulnerable to them. There is lack of information on the prevalence of eating disorders in Saudi Arabia. The current study aimed to investigate the prevalence of eating disorders among female undergraduate university students in Taif city, Saudi Arabia. Read More

    Evaluation and Phylogenetic Analysis of Regular Rabies Virus Vaccine Strains.
    Arch Iran Med 2018 Mar 1;21(3):101-110. Epub 2018 Mar 1.
    Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    Background: This study aimed to evaluate Rabies virus vaccine strains. The obtained results may be helpful for vaccine producers and researchers to compare the strains with wild type and other vaccine strains and select the correct strain to challenge their products.

    Methods: Fourteen rabies virus vaccine strains were compared with each other. Read More

    Assessing the Relation of Epicardial Fat Thickness and Volume, Quantified by 256-Slice Computed Tomography Scan, With Coronary Artery Disease and Cardiovascular Risk Factors.
    Arch Iran Med 2018 Mar 1;21(3):95-100. Epub 2018 Mar 1.
    Department of Radiology, Shaheed Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
    Background: This study aimed to investigate the association between epicardial adipose tissue (EAT) and coronary artery disease (CAD) as well as cardiovascular risk factors.

    Methods: Complete medical records of subjects were reviewed and cardiovascular risk factors were recorded. Epicardial fat volume (EFV) and epicardial fat thickness (EFT) were measured using digital volumetry of acquired images using a 256-slice CT-scanner. Read More

    Drug Use for Secondary Prevention of Cardiovascular Diseases in Golestan, Iran: Results From the Golestan Cohort Study.
    Arch Iran Med 2018 Mar 1;21(3):86-94. Epub 2018 Mar 1.
    Digestive Disease Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
    Background: Little is known about secondary prevention of cardiovascular diseases, using cardio-protective drugs, in the community-level, especially in low- and middle-income countries. We aimed to assess main drug use and its predictors in Northeast of Iran.

    Methods: This is a cross-sectional analysis on the Golestan Cohort Study data (2004-2008) with 50 045 participants. Read More

    Primary Nonsecretory Plasma Cell Leukemia With Multiple Chromosomal Abnormalities: A Case Report.
    Arch Iran Med 2018 Jan 1;21(1):41-43. Epub 2018 Jan 1.
    Department of Laboratory Medicine, National Defense Medical College Hospital, Tokorozawa, Japan.
    Primary nonsecretory plasma cell leukemia (PCL) is an extremely rare type of multiple myeloma. Here, we report a case of nonsecretory PCL with no previous history of multiple myeloma. The case exhibited extremely low levels of serum immunoglobulin and light chain, no detectable serum M-protein or free light chain restriction, no urine BJP, and no cytoplasmic light chain expression in flow cytometry. Read More

    Intellectual Disability and Ataxia: Genetic Collisions.
    Arch Iran Med 2018 Jan 1;21(1):29-40. Epub 2018 Jan 1.
    Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
    Intellectual disability (ID) is a common and highly heterogeneous neurodevelopmental disorder. The prevalence of ID is around 1%-3% in the general population. ID is associated with a wide range of additional neurological disabilities and the results of various studies have disclosed the co-morbidity of ID and ataxia. Read More

    Food Security and its Related Factors in the Rural Households of Bam City in Iran: A Logistic Regression Model Approach.
    Arch Iran Med 2018 Jan 1;21(1):26-28. Epub 2018 Jan 1.
    Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.
    Awareness of the food security status of rural population and its influencing factors is essential for policy makers, public health institutions and the development of rural programs. This descriptive cross-sectional study was conducted in 2017 on 384 rural households in Bam city. The data was collected via the 6-item USDA questionnaire. Read More

    Adherence to Principles of Medical Ethics Among Physicians in Mazandaran Province, Iran.
    Arch Iran Med 2018 Jan 1;21(1):19-25. Epub 2018 Jan 1.
    Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
    Background: Considering that medical ethics is an applied subject providing systematic solutions to help physicians with moral issues, this research aimed to evaluate adherence to the principles of medical ethics among physicians on the basis of attitude of physicians of Mazandaran province.

    Methods: This cross-sectional study was conducted in Mazandaran province, Iran during 2015. A researcher-made questionnaire was used for data collection. Read More

    Genetic Variation in NFKB1 Gene Influences Liver Enzyme Levels in Morbidly Obese Women.
    Arch Iran Med 2018 Jan 1;21(1):13-18. Epub 2018 Jan 1.
    Department of Medical Biology, Istanbul Aydin Medical Faculty, Istanbul Aydin University, Istanbul, Turkey.
    Background: Morbid obesity (MO), characterized by low-grade inflammation, is associated with increased C-reactive protein (CRP). NF-KB is a candidate factor for inflammatory responses in inflammatory diseases such as obesity. The objective of our study was to investigate the relationship between NFKB1 gene variations and the risk of MO in the context of the high/normal level of liver enzymes such as Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), and alkaline phosphatase (ALP). Read More

    C-Reactive Protein Levels and Clinical Outcomes in Stroke Patients: A Prospective Cohort Study.
    Arch Iran Med 2018 Jan 1;21(1):8-12. Epub 2018 Jan 1.
    Department of Neurology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
    Background: The C-reactive protein (CRP) level, as an early prognostic factor of functional outcome after stroke, may be of clinical importance. The aim of this study was to determine the prognostic value of CRP on functional outcome and death in stroke patients.

    Methods: This prospective study was conducted from 2015 to 2016 in Hamadan province, Iran. Read More

    Effects of Probiotic Supplementation on Hormonal Profiles, Biomarkers of Inflammation and Oxidative Stress in Women With Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Arch Iran Med 2018 Jan 1;21(1):1-7. Epub 2018 Jan 1.
    Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
    Background: To the best of our knowledge, data on effects of probiotic administration on hormonal profiles, biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome (PCOS) are scarce. This investigation was conducted to assess the effects of probiotic supplementation on hormonal profiles, biomarkers of inflammation and oxidative stress in women with PCOS.

    Methods: This randomized, double-blind, placebo-controlled trial was conducted on 60 women with PCOS, aged 18-40 years old. Read More

    Acute Suppurative Thyroiditis with Thyroid Abscess and Bilateral Pneumonia: A Case Report.
    Arch Iran Med 2018 Feb 1;21(2):79-81. Epub 2018 Feb 1.
    Faculty of Medicine, University of Nis, Serbia.
    Acute suppurative thyroiditis (AST) leading to thyroid abscess is a rare clinical entity. The aim of this article is to demonstrate a case of severe bilateral pneumonia which originated from a thyroid abscess. The authors report the case of a 57-year-old woman with severe bilateral pneumonia of thyroid origin. Read More

    Downregulation of GLUT3 Promotes Apoptosis and Chemosensitivity of Acute Myeloid Leukemia Cells via EGFR Signaling.
    Arch Iran Med 2018 Feb 1;21(2):73-78. Epub 2018 Feb 1.
    Department of Hematology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
    Background: Glucose transporter 3 (GLUT3) plays an important role in tumor progression and drug resistance in numerous malignancies, including acute myeloid leukemia (AML). However, the effect of GLUT3 silencing on treatment of AML remains poorly understood. The purpose of this study was to investigate role of GLUT3 in proliferation and chemosensitivity of AML and its underlying mechanisms. Read More

    Enterobius vermicularis: A Cause of Abdominal Pain Mimicking Acute Appendicitis in Children. A Retrospective Cohort Study.
    Arch Iran Med 2018 Feb 1;21(2):67-72. Epub 2018 Feb 1.
    Department of Pediatric Surgery, Hedi Chaker Hospital, 3029 Sfax, Tunisia.
    Background: Enterobius vermicularis (EV) is the most common helminthic infection in the world. This small parasite is predominant in the pediatric population. The presence of EV in the appendix can cause or mimick appendicitis. Read More

    Maternal Anthropometric Characteristics and Adverse Pregnancy Outcomes in Iranian Women: A Confirmation Analysis.
    Arch Iran Med 2018 Feb 1;21(2):61-66. Epub 2018 Feb 1.
    Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.
    Background: Adverse pregnancy outcome are frequent in developing countries. Pregnancy outcomes are influenced by numerous factors. It seems that maternal anthropometric indices are among the most important factors in this era. Read More

    Short-term Assessment of HSCT Effects on the Hypothalamus-Pituitary Axis in Pediatric Thalassemic Patients.
    Arch Iran Med 2018 Feb 1;21(2):56-60. Epub 2018 Feb 1.
    Hematology-Oncology and Stem Cell Transplantation Research Center of Tehran University of Medical Sciences, Tehran, Iran.
    Background: Beta thalassemia major (BTM) and its treatment by hematopoietic stem cell transplantation (HSCT) may have deleterious effects on the endocrine systems. We assessed endocrine complications of HSCT in pediatric patients for 3 months.

    Methods: In 20 (6 female) pediatric major thalassemic patients (mean age of 10. Read More

    Annual Trends of Gastrointestinal Cancers Mortality in Iran During 1990-2015; NASBOD Study.
    Arch Iran Med 2018 Feb 1;21(2):46-55. Epub 2018 Feb 1.
    Digestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
    Background: Gastrointestinal (GI) neoplasms are among the most common cancers in Iran. This study aimed to measure annual trends in mortality rates from GI cancers in Iran between 1990 and 2015.

    Methods: This study was part of an ongoing study termed the 'National and Subnational Burden of Diseases' study in Iran. Read More

    The Westminster Medical College and Hospital in Urmia, Iran, 1879-1915.
    Arch Iran Med 2017 Dec 30;20(12):760-766. Epub 2017 Dec 30.
    Department of Orthopedics, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran.
    Background: The American Presbyterian Missionary in Iran accomplished medical activities in Urmia. Doctor Joseph Plumb Cochran established the first modern medical college (the Westminster College) in 1879 and built a modern hospital of that time (the Westminster Hospital). The medical college and hospital trained 34 native physicians that practiced in the northwest of Iran and its neighboring regions. Read More

    Endovascular Repair of Interrupted Aortic Arch: Approach with Hope for Fewer Complications.
    Arch Iran Med 2017 Dec 23;20(12):756-759. Epub 2017 Dec 23.
    Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
    Interrupted aortic arch (IAA) is a rare congenital malformation defined as complete discontinuity between ascending and descending parts of aorta. We present a case of IAA, which was referred to us due to dilatation of proximal and mid parts of his thoracic aorta accompanied by narrowing of aorta proximal to the branching of the left subclavian artery. Further evaluation revealed interruption of aorta at the proximal part of descending thoracic aorta by a transverse septum along with several collateral formations. Read More

    Potential Correlation Between Circulating Fetuin-A and Pentraxin-3 With Biochemical Parameters of Calcification in Hemodialysis Patients.
    Arch Iran Med 2017 Dec 1;20(12):752-755. Epub 2017 Dec 1.
    School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
    Background: The strong correlation between vascular calcification and cardiovascular risk, which is a major cause of mortality in hemodialysis (HD) patients, has been well established. Fetuin-A is an inhibitor of vascular calcification, and pentraxin 3 (PTX3) is produced at the site of inflammation, which is associated with cardiovascular disease (CVD). The main purpose of this study was evaluating the correlation between fetuin-A and PTX3 with some biochemical parameters effective upon vascular calcification in HD patients. Read More

    Iran Pituitary Tumor Registry: Description of the Program and Initial Results.
    Arch Iran Med 2017 Dec 31;20(12):746-751. Epub 2017 Dec 31.
    Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
    Background: This study was designed to present initial results on clinical presentation, therapeutic modalities, and outcome information of patients with pituitary tumors registered in Iran Pituitary Tumor Registry (IPTR).

    Methods: We collected data from a web-based electronic medical records of patients with various pituitary tumors referred to four tertiary care centers in the country. Retrospective analysis was performed on demographic, clinical, and therapeutic information of 298 patients including 51 clinically nonfunctioning adenoma (CNFA), 85 acromegaly, 135 prolactinoma, and 27 Cushing's disease (CD). Read More

    Voluntary Wheel Running Induces Exercise-Seeking Behavior in Male Rats: A Behavioral Study.
    Arch Iran Med 2017 Dec 1;20(12):740-745. Epub 2017 Dec 1.
    Department of Psychology, University of Otago, Dunedin, New Zealand.
    Background: Research evidence shows that exercise is associated with positive physical and mental health. Moreover, exercise and wheel running in rats activate overlapping neural systems and reward system. The most commonly used models for the study of rewarding and aversive effects of exercise involve using treadmill and wheel running paradigms in mice or rats. Read More

    Adverse Cardiometabolic Effect in Bilateral/Unilateral Oophorectomy Versus Natural Menopause: Results of Over a Decade Follow-up Among Iranian Women.
    Arch Iran Med 2017 Dec 1;20(12):734-739. Epub 2017 Dec 1.
    Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Background: To compare metabolic changes in 3 groups of postmenopausal women: those who had undergone bilateral salpingooophorectomy + hysterectomy (BSO + H), those with hysterectomy ± unilateral salpingo-oophorectomy (H ± USO), and those who reached natural menopause during follow-up.

    Methods: This longitudinal study was performed on 543 female participants of the Tehran Lipid and Glucose Study (TLGS) who experienced surgical menopause (BSO + H or H ± USO) or natural menopause over a 12-year period. During the follow-up period, changes in metabolic and biochemical profiles were compared between surgically and naturally menopausal women (NMW). Read More

    Feasibility of Colon Cancer Screening by Fecal Immunochemical Test in Iran.
    Arch Iran Med 2017 Dec 1;20(12):726-733. Epub 2017 Dec 1.
    Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
    Background: Colorectal cancer (CRC) is the third most common cancer in Iran, where there is no mass screening for the disease yet. We aimed to measure the feasibility of a pilot CRC screening program based on fecal immunochemical test (FIT) in Iranian population and the implications for scaling-up at the national level.

    Methods: A single quantitative FIT was offered by health navigators to individuals aged between 45 and 75 years in primary health centers in rural and urban areas in Tehran. Read More

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