1,845 results match your criteria Archives of Iranian medicine[Journal]


Response to the Comment on "The Editor and the Author at Fault: A Lesson from Recent Retractions".

Arch Iran Med 2019 Feb 1;22(2):108. Epub 2019 Feb 1.

Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

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February 2019

Editor and the Author and Retractions.

Arch Iran Med 2019 Feb 1;22(2):107. Epub 2019 Feb 1.

Honorary professor, Dr DY Patil University, Pune, India.

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February 2019

Reply to "Enterobius Vermicularis: Uncommon Clinical Presentations".

Arch Iran Med 2019 Feb 1;22(2):106. Epub 2019 Feb 1.

Sfax Medical School, Sfax, Tunisia.

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February 2019

Enterobius vermicularis: Uncommon Clinical Presentations.

Arch Iran Med 2019 Feb 1;22(2):104-105. Epub 2019 Feb 1.

Adjunct-professor, Internal Medicine Department of Armed Forces Hospital and Catholic University, Brasília-DF, Brazil.

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February 2019

Calcified Cerebral Hydatid Cyst Presenting with Seizure.

Arch Iran Med 2019 Feb 1;22(2):102-103. Epub 2019 Feb 1.

Pathology and Stem Research Center, Pathology Department, Afzalipour Medical School, Kerman University of Medical Sciences, Kerman, Iran.

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February 2019
3 Reads

Acute Fulminant-Onset Synchronized CMV-Ulcerative Colitis.

Arch Iran Med 2019 Feb 1;22(2):99-101. Epub 2019 Feb 1.

Tepecik Education and Research Hospital, Department of Gastroenterology, Yenisehir-Izmir, Turkey.

Cytomegalovirus (CMV) is an agent which exists asymptomatically in most individuals and may cause latent life-time infection following contamination. Symptomatic CMV infection develops most commonly in organ transplant recipients and in individuals who receive immunosuppressive drugs, undergo haemodialysis or have acquired immunodeficiency syndrome. The link between ulcerative colitis and CMV infection and the efficacy of antiviral therapy in these individuals have been demonstrated. Read More

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February 2019
1 Read

Loss of Inverse Association between Framingham Risk Score and Estimated Glomerular Filtration Rate in Moderate to Severe Diabetic Kidney Disease.

Arch Iran Med 2019 Feb 1;22(2):91-98. Epub 2019 Feb 1.

Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Background: We investigated the association of estimated glomerular filtration rate (eGFR) with Framingham risk score (FRS), and actual cardiovascular disease (CVD) in patients with type 2 diabetes (T2DM). We also assessed improvement in FRS for prediction of CVD after inclusion of eGFR and albuminuria.

Methods: A total of 571 patients with T2DM and mean age 55 were divided into 2 groups based on the presence of CVD. Read More

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February 2019
2 Reads

Evaluation of the Capability of the Wharton's Jelly Mesenchymal Stem Cell Aggregates to Express the Markers of Three Germ Cell Lineages.

Arch Iran Med 2019 Feb 1;22(2):85-90. Epub 2019 Feb 1.

Laboratory for Stem Cell Research, Department of Anatomical Sciences, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: The ability of stem cells to differentiate into different cell types makes them a key component of healing damage in regenerative medicine. As human umbilical cord Wharton's jelly (HUCWJ) is available non-invasively, HUCWJ does not raise any ethical issues with higher differentiation potential compared to adult stem cells. With the ability to express embryonic stem cell markers, HUCWJ can be considered as a good candidate in regenerative medicine applications. Read More

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February 2019

Evaluation of Factors Related to Mortality Caused by Firearm Injury: A Retrospective Analysis from Malatya, Turkey.

Arch Iran Med 2019 Feb 1;22(2):80-84. Epub 2019 Feb 1.

Department of Emergency Medicine, School of Medicine, Inonu University, Malatya, Turkey.

Background: Firearm related injuries continue to increase throughout the world and they become the first or second cause of mortality in worldwide. The present study aimed to determine the factors that affect mortality in firearm injuries.

Methods: The patients which were admitted to emergency service between January 2011 and December 2015 due to firearm injuries, were reviewed from hospital records. Read More

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February 2019

Hepatitis C (HCV) Viremic Rate and its Correlation to Demographic Factors among HCV Confirmed Iranian Blood Donors.

Arch Iran Med 2019 Feb 1;22(2):76-79. Epub 2019 Feb 1.

Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.

Background: Hepatitis C virus (HCV) viremia is described as persistent HCV RNA among HCV exposed individuals. HCV viremic rate is defined as the proportion of anti-HCV positive and HCV RNA positive individuals to total anti-HCV positive individuals. Knowledge about HCV viremic rate increases understanding HCV epidemiology and provides the likelihood of HCV viremia infection in a given population. Read More

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February 2019

Quality of Life Changes in Iranian Patients Undergoing Female-to-Male Transsexual Surgery: A Prospective Study.

Arch Iran Med 2019 Feb 1;22(2):71-75. Epub 2019 Feb 1.

Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Background: Gender identity disorder (GID) is associated with various adverse health outcomes as well as psychiatric problems. Quality of life (QOL) in patients after surgery is an important issue, as some cases report dissatisfaction and regret after surgery. The present study compared QOL in female-to-male (FTM) GID patients before and after gender reassignment surgery (GRS) in an Iranian population. Read More

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February 2019
1 Read

Impact of Age at Menarche on Breast Cancer: The Assessment of Recall Bias.

Arch Iran Med 2019 Feb 1;22(2):65-70. Epub 2019 Feb 1.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: Our aim was to determine the association between age at menarche (AAM) and breast cancer adjusted for recall bias (misclassification) in AAM.

Methods: We have used data provided from a case-control study conducted in Iran from 2005 to 2009. The cases and controls were frequency matched based on 5-year age groups and region of residence. Read More

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February 2019
1 Read

Bam Earthquake Survivors' Mental Health Status 12 Years after the Earthquake: A Population-Based Study.

Arch Iran Med 2019 Feb 1;22(2):59-64. Epub 2019 Feb 1.

Department of Epidemiology, Bam University of Medical Sciences, Bam, Iran.

Background: Mental health is one of the characteristic benchmarks of public health. This research aimed to evaluate mental health of survivors of the Bam earthquake which occurred in 2003 twelve years after the earthquake in fall of 2015.

Methods: The statistical population of this cross-sectional study were people over 16 years of age who were present at the time of the earthquake in the city of Bam. Read More

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February 2019
1 Read
1.108 Impact Factor

Photoclinic Diagnosis: Basal cell adenocarcinoma.

Arch Iran Med 2019 Jan 1;22(1):57-58. Epub 2019 Jan 1.

Department of Oral Pathology and Microbiology, KLE Academy of Higher Education and Research [KLE University], KLE VK Institute of Dental Sciences and Hospital, Belagavi- 590010, Karnataka, India.

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January 2019

Electrocardiographic Changes Following Acute Hydralazine Overdose.

Arch Iran Med 2019 Jan 1;22(1):53-56. Epub 2019 Jan 1.

Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Hydralazine is an FDA-approved antihypertensive agent which has been utilized for years either alone or in combination with other medications especially the beta-blockers. Hydralazine works as a direct-acting vasodilator, thereby exerting a decrease in vascular resistance and increase in intravascular volume. When overdosed, hydralazine applies its toxic effects by extending its pharmacological action, which produces hypotension, syncope, tachycardia, and nausea. Read More

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January 2019
1 Read
1.108 Impact Factor

Metastatic Tumors to the Pancreas, a Single Center Study.

Arch Iran Med 2019 Jan 1;22(1):50-52. Epub 2019 Jan 1.

Department of Hepatobiliary Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Most pancreatic masses are primary ductal adenocarcinomas; however, with the advent of new imaging studies and increasing survival of cancer patients, there are more cases with the diagnosis of secondary metastatic cancer to the pancreas. There is no study regarding cancer metastases to the pancreas from Iran. In this study, we retrieved all of the cases with the diagnosis of secondary cancer of pancreas in the affiliated hospitals of Shiraz University of Medical Sciences. Read More

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January 2019
2 Reads

Risk Ratio Estimation in Longitudinal Studies.

Arch Iran Med 2019 Jan 1;22(1):46-49. Epub 2019 Jan 1.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Longitudinal studies are very common in medical, behavioral, and interventional sciences. One measure of effect of interest in longitudinal studies is risk ratio, naturally estimated by log-binomial regression which suffers from convergence problem. Odds ratio does not well approximate risk ratio when the outcome is common, so alternative methods have been introduced in cohort studies with one follow-up visit. Read More

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January 2019

The PERSIAN Guilan Cohort Study (PGCS).

Arch Iran Med 2019 Jan 1;22(1):39-45. Epub 2019 Jan 1.

Digestive Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

The Guilan cohort study was conducted on 10520 men and women between 35-70 years of age in Guilan province and Some'e Sara county, northern Iran, from October 8, 2014 to January 20, 2017 as part of the Prospective Epidemiological Research Studies in Iran (PERSIAN). Eligible participants were contacted over the phone and were invited to refer to the cohort center. Demographic information was inquired during the phone call. Read More

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January 2019
2 Reads
1.108 Impact Factor

TMEM16A as a Potential Biomarker in the Diagnosis and Prognosis of Lung Cancer.

Arch Iran Med 2019 Jan 1;22(1):32-38. Epub 2019 Jan 1.

Department of Respiratory Medicine, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.

Background: Transmembrane protein 16A (TMEM16A), also known as ANO1 (anoctamin-1), was reported to be vital in the growth and invasion of several malignancies. However, role of TMEM16A in lung cancer remained unclear. The aim of this study was to evaluate the expression of TMEM16A and its significance in lung cancer. Read More

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January 2019
3 Reads

Reference Values for Serum Lipid Profiles in Iranian Adults: Tehran Lipid and Glucose Study.

Arch Iran Med 2019 Jan 1;22(1):24-31. Epub 2019 Jan 1.

Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Lipid abnormalities are major risk factors for cardiovascular diseases. In addition to age and sex, other variables can affect serum lipid levels, warranting the determination of population-specific reference values. This study aimed to determine age- and sex-specific reference values for serum total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and triglycerides (TG) in healthy Tehranian adults. Read More

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January 2019
1.108 Impact Factor

Developing and Assessing the Validity and Reliability of an Iranian Food Security Questionnaire.

Arch Iran Med 2019 Jan 1;22(1):11-23. Epub 2019 Jan 1.

Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Food insecurity has a considerable impact on the social, physical, and psychological well-being of people and there is no food security assessment tool specific for Iranians. This study aimed to develop and assess the validity and reliability of an Iranian-specific food security questionnaire.

Methods: The food security questionnaire was developed by five food security specialists by evaluating all available questionnaires (not specific to Iranians) in terms of applicability to Iranians. Read More

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January 2019
1 Read

Generation of CD19-Targeted Chimeric Antigen Receptor T Cells.

Arch Iran Med 2019 Jan 1;22(1):7-10. Epub 2019 Jan 1.

Cell-Based Therapies Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: Current advancements in the field of chimeric antigen receptor (CAR) therapy, particularly U.S. FDA approval of Kymriah and Yescarta, heralds a new era of cancer treatment. Read More

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January 2019
1 Read

Completeness and Accuracy of Death Registry Data in Golestan, Iran.

Arch Iran Med 2019 Jan 1;22(1):1-6. Epub 2019 Jan 1.

Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.

Background: We aimed to evaluate completeness and accuracy of the Golestan Death Registry (GDR) to identify cancer-related causes of death (CCoD).

Methods: The GDR data (2004-2015) were compared with cancer data collected from clinical/pathological sources (the considered gold standard) by the Golestan Population-Based Cancer Registry (GPCR). Using a linkage method, matched cases, including subjects with CCoD and those with ill-defined cause of death (ICoD) (garbage codes), were identified and entered into the final analysis as study subjects. Read More

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January 2019
7 Reads

Photoclinic: Opaque hemithorax.

Arch Iran Med 2018 Dec 1;21(12):613-615. Epub 2018 Dec 1.

Internal Medicine Department, Armed Forces Hospital, Brasília-DF, Brazil.

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December 2018
1 Read

Extramedullary Manifestation of Multiple Myeloma in the Oral Cavity.

Arch Iran Med 2018 Dec 1;21(12):611-612. Epub 2018 Dec 1.

Pathologist, A.C.Camargo Cancer Center, São Paulo, Brazil.

Background: Extramedullary plasmacytomas occurs in about 20% of multiple myeloma (MM) recurrences. Extramedullary disease seems to respond poorly to thalidomide and has adverse prognostic implication. When disease recurs in the oral cavity with soft tissue infiltration, some authors defend upfront surgical excision prior to radiotherapy with the aim of achieving better local control. Read More

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December 2018
1 Read

Multiple Gastritis Cystica Profunda in a Patient without Gastric Surgery History.

Arch Iran Med 2018 Dec 1;21(12):608-610. Epub 2018 Dec 1.

Department of General Surgery, İstinye University Faculty of Medicine, Istanbul, Turkey.

Gastritis cystica profunda (GCP) is a rare condition characterized by polypoid cystic ectasia of the submucosal layer with cystic dilatation of the glandular structures of the stomach. The probable pathogenesis refers to degradation of the integrity of the muscularis mucosa and migration of epithelial cells to the submucosal layer. The most common cause known in the literature for this occurrence is previous stomach surgery. Read More

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December 2018
1 Read

Recent Advances on Nucleolar Functions in Health and Disease.

Arch Iran Med 2018 Dec 1;21(12):600-607. Epub 2018 Dec 1.

Afzalipour Kerman University of Medical Sciences, Kerman, Iran.

The nucleolus is an internuclear organelle without a visible membrane via the light microscope inside the cell nucleus. It is the main site for synthesis of ribosome as a complex machine for coordinating protein production. It forms around a specific chromosomal feature called the nucleolar organizing region (NOR) which possesses numerous ribosomal DNA (rDNA). Read More

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December 2018
14 Reads
1.108 Impact Factor

Complications of Fusionless Correction of Early Onset Scoliosis Using Dual Growing Rods.

Arch Iran Med 2018 Dec 1;21(12):595-599. Epub 2018 Dec 1.

Bone Joint and Related Tissue Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Growing rods are increasingly used for treatment of early onset scoliosis (EOS) worldwide. Beside promising outcomes, some authors are concerned about high rates of complications. In the current clinical trial, complications of EOS surgery using dual growing rods were investigated. Read More

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December 2018
7 Reads

Children With Vitamin D Deficiency: Is A Wrist X-Ray Necessary?

Arch Iran Med 2018 Dec 1;21(12):589-594. Epub 2018 Dec 1.

Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran.

Background: Rickets is failure in mineralization of growing bone and cartilage due to extreme vitamin D deficiency (VDD). The study aimed to identify rickets among vitamin D deficient children and determine any relationship between clinical findings and paraclinical evidence.

Methods: This study was conducted in two stages. Read More

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December 2018
4 Reads
1.108 Impact Factor

A Study on Radiation Dose Received by Patients during Extracorporeal Shock Wave Lithotripsy.

Arch Iran Med 2018 Dec 1;21(12):585-588. Epub 2018 Dec 1.

Department of Medical Physics, Lorestan University of Medical Sciences, Khorramabad, Iran.

Background: Extracorporeal shock wave lithotripsy (ESWL) is considered as the method of choice for treatment of most stone diseases. The present study aims to evaluate radiation dose received by patients undergoing ESWL.

Methods: In total, 46 patients from both genders were referred to the Shohadaye Ashayer hospital of Khorramabad, Iran and were included in the present study. Read More

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December 2018
3 Reads

Longitudinal Analyses of Gut-Associated Bacterial Microbiota in Ulcerative Colitis Patients.

Arch Iran Med 2018 Dec 1;21(12):578-584. Epub 2018 Dec 1.

Department of Food Hygiene, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Background: The normal colonic microbiota is associated with the etiology of ulcerative colitis (UC). Several bacterial species are associated with the initiation and amplification of disease process. However, the etiology and mechanism of UC are poorly understood. Read More

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December 2018
4 Reads

Comparison of Lipid Ratios to Identify Metabolic Syndrome.

Arch Iran Med 2018 Dec 1;21(12):572-577. Epub 2018 Dec 1.

Endorinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.

Background: The objective of this study was to compare various lipid ratios for detection of metabolic syndrome (MetS) in the Iranian general population.

Methods: This cross-sectional study involved 5677 subjects aged ≥18 years from the general population in Kerman, Iran. Associations between lipid ratio quartiles and MetS were analyzed using logistic regression models. Read More

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December 2018
1 Read

Evaluating the Women Health Volunteers Program in Iran- a Quarter Century Experience (1992-2016).

Arch Iran Med 2018 Dec 1;21(12):566-571. Epub 2018 Dec 1.

National Institute for Health Research (NIHR), Tehran University of Medical Sciences, Tehran, Iran.

Background: Running for more than 25 years, the Women Health Volunteers (WHV) program in Iran has made many great achievements. Considering the new expectations from the health system, this national program needs to be revised and undergo fundamental changes. Although many studies have been conducted to evaluate this program, there still is a lack of a comprehensive nationwide assessment containing policy recommendations. Read More

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December 2018
2 Reads
1.108 Impact Factor

The Burden of Road Traffic Injuries in Iran and 15 Surrounding Countries: 1990-2016.

Arch Iran Med 2018 Dec 1;21(12):556-565. Epub 2018 Dec 1.

Professor of Global Health, Institute for Health Metrics and Evaluation (IHME), University of Washington, Seattle, USA.

Background: The Global Burden of Disease (GBD) Study provides estimates of deaths, years of life lost (YLL), years of life lived with disability (YLD), and disability-adjusted life years (DALYs) due to 249 causes of death, 315 diseases and injuries, and 79 behavioral, environmental, occupational, and metabolic risk factors in 195 countries, territories, and regions by sex and 20 age categories in 195 countries and regions since 1990. In this study, we aimed to present the burden of road traffic injuries (RTIs) in Iran and 15 surrounding countries in 1990-2016.

Methods: The standard Cause of Death Ensemble modeling (CODEm) is used to estimate deaths due to all causes of injury by age, sex, country and year. Read More

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December 2018
1 Read
1.108 Impact Factor

A Brief History of Oral and Maxillofacial Pathology in Iran.

Arch Iran Med 2018 Nov 1;21(11):551-555. Epub 2018 Nov 1.

Academy of Medical Sciences Islamic Republic of Iran, Tehran, Iran.

This is a brief look at the establishment and development of oral and maxillofacial pathology in Iran. The program of the oral and maxillofacial pathology at first was integrated into the curriculum of the Dental School of Tehran University in 1960. The Iranian Society of Oral and Maxillofacial Pathologists was officially founded in 1999. Read More

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November 2018
1 Read
1.108 Impact Factor

Geographic and Ethnographic Variations of Hemoglobin A1C.

Arch Iran Med 2018 Nov 1;21(11):549-550. Epub 2018 Nov 1.

Research Center, Medicine, UNAM-UABJO, Oaxaca, México.

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November 2018
5 Reads

Huge Ectopic Parathyroid Adenoma.

Arch Iran Med 2018 Nov 1;21(11):547-548. Epub 2018 Nov 1.

Department of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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November 2018
3 Reads

A Lateral Neck Myeloid Sarcoma Presenting as Acute Otitis Externa.

Arch Iran Med 2018 Nov 1;21(11):544-546. Epub 2018 Nov 1.

Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.

Myeloid sarcoma (MS) is a solid extra-medullary tumor of immature myeloid cells which could occur before, during or after remission of acute leukemia at any site on the body. Owing to variation in differential diagnosis, pathologic evaluation and immunohistochemical staining are essential for definitive diagnosis. Rarely, MS has been shown as an isolated extramedullary relapse (iEMR) after allogeneic stem cell transplantation (allo-SCT), which often does not necessarily result in bone marrow involvement. Read More

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November 2018
2 Reads

Experimental Endometriosis: Review of the Literature Through a Century and the Iranian Experience.

Arch Iran Med 2018 Nov 1;21(11):536-543. Epub 2018 Nov 1.

Department of Nursing Science, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.

Although endometriosis is not a newly discovered disease, it has still remained enigmatic. Understanding the pathophysiology of this disease is still one of the challenges of gynecology and reproductive medicine. Therefore, the subject of endometriosis treatment faces many questions to be answered. Read More

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November 2018
1 Read

Cytochrome P450 (CYP450,2D6*A), N-Acetyltransferase-2 (NAT2*7, A) and Multidrug Resistance 1 (MDR1 3435 T) Alleles Collectively Increase Risk of Ulcerative Colitis.

Arch Iran Med 2018 Nov 1;21(11):530-535. Epub 2018 Nov 1.

Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, USA.

Background: Discovering the association between genetic variations of metabolizing enzymes with idiopathic diseases such as ulcerative colitis (UC) may not only be an auxiliary agent in diagnosis but also could be an effective pharmacotherapy for inflammatory bowel disease (IBD). The aim of the present case-control study was to determine the association of cytochrome P450 2D6 (CYP2D6 *4), N-acteyltransferase-2 (NAT2*7) and multidrug resistance 1 (MDR1) 3435 C/T genotypes with UC susceptibility and thiopurine methyltransferase (TPMT) enzyme activity.

Methods: TPMT activity was measured by high performance liquid chromatography (HPLC) and genotypes for the 3 mentioned polymorphisms were determined in 215 unrelated UC patients and 212 unrelated healthy controls by polymerase chain reactionrestriction fragment length polymorphism (PCR-RFLP) in a Kurdish population from Iran. Read More

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November 2018
2 Reads
1.108 Impact Factor

Sleep Quality and its Main Determinants Among Staff in a Persian Private Hospital.

Arch Iran Med 2018 Nov 1;21(11):524-529. Epub 2018 Nov 1.

Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.

Background: Having good quality of sleep is essential to good health. Sleep disorders could incur intangible expenses. The aim of this cross-sectional study was to evaluate the Persian version of the Pittsburgh Sleep Quality Index (PSQI-P) questionnaire administered to 3 categories of workers (clinical personnel, clerical staff, and logistics workers) in a private hospital located in Tehran, Iran. Read More

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November 2018
18 Reads
1.108 Impact Factor

Correlation of Prognostic Gleason Grade Grouping and Histopathological Parameters: Can the "New System" Reflect the Pathological Perspective for Prognosis?

Arch Iran Med 2018 Nov 1;21(11):518-523. Epub 2018 Nov 1.

İzmir Katip Çelebi University Ataturk Training and Research Hospital Department of Pathology, İzmir, Turkey.

Background: Gleason score is one of the strongest prognostic predictors of prostate cancer;however, a change was published which is a 5 step grouping system of prostatic adenocarcinomas according to their Gleason scores. The aim of this study is to determine the relationship between histopathological findings and prognosis of tumors subgrouped according to the new Gleason grade grouping system.

Methods: A total of 163 radical prostatectomies subgrouped into 5 prognostic groups were investigated for prognostic features such as pathological stage, extraprostatic extension, surgical margin status, involvement of seminal vesicles, perineural invasion, necrosis, vascular invasion, ganglionic involvement, concomitant high grade prostatic intraepithelial neoplasia (HPIN) in addition to other microscopic features of tumors such as the presence of mucin and foamy cytoplasmic change between groups. Read More

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November 2018
3 Reads

Patients With Invasive Ductal Carcinoma Have Reduced Levels of Decorin Expression in Their Breast Tissue Compared to Patients With Fibroadenoma While Plasma Decorin Remains Unchanged.

Arch Iran Med 2018 Nov 1;21(11):509-517. Epub 2018 Nov 1.

Department of Genetics and Molecular Medicine, School of Medicine, Zanjan University of Medical Sciences (ZUMS), Zanjan, Iran.

Background: Reduction in the level of tissue decorin is a hallmark of many types of cancer including breast carcinoma. However, reduced decorin expression has also been reported in several types of benign tumors to the extent that it has been proposed as a tissue marker to differentiate malignant from benign tumors. The aim of this study was to investigate the potential role of plasma decorin to distinguish breast cancer from fibroadenoma, the second most common type of benign tumor, after fibrocystic disease. Read More

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November 2018
1 Read
1.108 Impact Factor

Eicosapentaenoic Acid and Vitamin E Against Doxorubicin Induced Cardiac and Renal Damages: Role of Cytochrome c and iNOS.

Arch Iran Med 2018 Nov 1;21(11):502-508. Epub 2018 Nov 1.

Pharmacology and Toxicology Department, Faculty of Pharmacy, October University for Modern Sciences and Arts, Egypt.

Background: The current study aimed to evaluate the mechanisms involved in protection against doxorubicin-induced cardiac and renal toxicities upon treatment with eicosapentaenoic acid and vitamin E.

Methods: Rats were randomly assigned to 4 groups: normal control, doxorubicin inducted control, eicosapentaenoic acid treated group and a final group pretreated with vitamin E. Lipid peroxidation, reduced glutathione (GSH) and tumor necrosis factor-alpha (TNF-α) contents as well as glutathione peroxidase (GPx), superoxide dismutase (SOD) and myeloperoxidase (MPO) activities were assessed. Read More

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November 2018
3 Reads

An Approach Towards Reducing Road Traffic Injuries and Improving Public Health Through Big Data Telematics: A Randomised Controlled Trial Protocol.

Arch Iran Med 2018 Nov 1;21(11):495-501. Epub 2018 Nov 1.

Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Objective: Deaths due to road traffic accidents (RTAs) are a major public health concern around the world. Developing countries are over-represented in these statistics. Punitive measures are traditionally employed to lower RTA related behavioural risk factors. Read More

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November 2018
8 Reads
1.108 Impact Factor

Mirza Ali Hamedani: An Influential Physician in the Qajar Period, Iran.

Arch Iran Med 2018 Oct 1;21(10):491-494. Epub 2018 Oct 1.

Department of History, Faculty of Literature and Humanities- Dr Ali Shariati, Ferdowsi University of Mashhad, Mashhad, Iran.

The knowledge of medicine underwent a revolution in the Qajar period, especially during the reign of Naser al-Din Shah Qajar (1831-1896 AD). The dispatch of students to Europe, establishment of Dar ul-Funun, Hafez al-Seheh Assembly, and clinics, entrance of European teachers and physicians to Iran, approval of medical rules by the parliament, introduction of a new therapeutic style, and translation of medical textbooks into Persian were some of the changes that occurred during this period. As a result, modern medicine influenced the Iranian-Islamic traditional medicine. Read More

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October 2018
16 Reads

Hemoglobin A1c Cut-off to Diagnose Diabetes in Iranian Population.

Arch Iran Med 2018 Oct 1;21(10):490. Epub 2018 Oct 1.

Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.

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October 2018
1 Read

Response to the Letter to the Editor.

Arch Iran Med 2018 Oct 1;21(10):489. Epub 2018 Oct 1.

Department of Pharmacology & Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

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October 2018
1 Read

Missed Links in the Determination of Challenges of Urban Family Physician Program.

Arch Iran Med 2018 Oct 1;21(10):488. Epub 2018 Oct 1.

Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.

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October 2018
4 Reads

Social Challenges of Mothers with Blindness in Iranian Setting.

Arch Iran Med 2018 Oct 1;21(10):486-487. Epub 2018 Oct 1.

Associate professor, Zahra Behboodi Moghadam, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery.

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October 2018
13 Reads