23,830 results match your criteria Archives of Disease in Childhood[Journal]


Risk factors for refractory anastomotic strictures after oesophageal atresia repair: a multicentre study.

Arch Dis Child 2018 Jul 14. Epub 2018 Jul 14.

Department of Paediatric Surgery and Intensive Care Children, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.

Objective: To determine the incidence of refractory anastomotic strictures after oesophageal atresia (OA) repair and to identify risk factors associated with refractory strictures.

Methods: Retrospective national multicentre study in patients with OA born between 1999 and 2013. Exclusion criteria were isolated fistula, inability to obtain oesophageal continuity, death prior to discharge and follow-up <6 months. Read More

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Does heavy metal chelation therapy improve the symptoms of autism spectrum disorder.

Arch Dis Child 2018 Jul 14. Epub 2018 Jul 14.

Discipline of Paediatrics, Trinity College Dublin, Dublin, Ireland.

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Fluid regimes for DKA.

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Arch Dis Child 2018 Jul 14. Epub 2018 Jul 14.

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Avoidable mortality from respiratory tract infection and sudden unexplained death in children with chronic conditions: a data linkage study.

Arch Dis Child 2018 Jul 14. Epub 2018 Jul 14.

Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, London, UK.

Objective: To determine the risk of death from two potentially avoidable causes with different aetiologies: respiratory tract infection (RTI) and sudden unexplained death (SUD) in children with and without chronic conditions.

Design: Whole-country, birth cohort study using linked administrative health databases from Scotland.

Setting And Participants: Children aged 2 months to less than 5 years in Scotland between 2000 and 2014. Read More

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Hypoventilation disproportionate to OSAS severity in children with Prader-Willi syndrome.

Arch Dis Child 2018 Jul 14. Epub 2018 Jul 14.

Paediatric Pulmonology Unit, First Department of Paediatrics, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.

Objective: To test the hypothesis that children with Prader-Willi syndrome (PWS) and obstructive sleep apnoea syndrome (OSAS) have hypercapnia for higher proportion of total sleep time (TST) than non-syndromic children with similar obstructive apnoea-hypopnoea index (OAHI).

Design: Cross-sectional study.

Setting: Two tertiary care hospitals. Read More

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In infant botulism, is equine-derived botulinum antitoxin (EqBA) an effective alternative therapy to human-derived botulinum immune globulin (BIG)?

Authors:
Joseph Moneim

Arch Dis Child 2018 Jul 14. Epub 2018 Jul 14.

University of Cambridge School of Clinical Medicine, Cambridge, UK.

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Two-thumb-encircling advantageous for lay responder infant CPR: a randomised manikin study.

Arch Dis Child 2018 Jul 14. Epub 2018 Jul 14.

Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Objective: Paediatric health providers and educators influence infant mortality through advocacy and training within families and communities. This research sought to establish the efficacy and training of two-finger versus two-thumb-encircling techniques for lone responder infant chest compressions with ventilations in initially trained infant caregivers.

Design: This is a randomised, cross-over educational intervention assessed on instrumented manikins using the 2015 guideline measures of quality infant cardiopulmonary resuscitation (CPR). Read More

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July 2018
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Antenatal ultrasound and autism.

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Arch Dis Child 2018 Jul 14. Epub 2018 Jul 14.

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Impact of breast milk intake on body composition at term in very preterm babies: secondary analysis of the Nutritional Evaluation and Optimisation in Neonates randomised controlled trial.

Arch Dis Child Fetal Neonatal Ed 2018 Jul 14. Epub 2018 Jul 14.

Neonatal Medicine, Chelsea and Westminster National Health Service Foundation Trust, London, UK.

Objective: To investigate the impact of breast milk (BM) intake on body composition at term in very preterm infants.

Design: Preplanned secondary analysis of the Nutritional Evaluation and Optimisation in Neonates Study, a 2-by-2 factorial randomised controlled trial of preterm parenteral nutrition (PN).

Setting: Four National Health Service hospitals in London and South-East England. Read More

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The secret sauce: secrets of high performing neonatal intensive care units.

Arch Dis Child Fetal Neonatal Ed 2018 Jul 13. Epub 2018 Jul 13.

Pediatrics, The George Washington University School of Medicine, Washington, DC, USA.

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Fetal surgery for spina bifida aperta.

Arch Dis Child Fetal Neonatal Ed 2018 Jul 13. Epub 2018 Jul 13.

Academic Department Development and Regeneration, Cluster Woman and Child, Biomedical Sciences, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium.

Spina bifida aperta (SBA) is one of the most common congenital malformations. It can cause severe lifelong physical and neurodevelopmental disabilities. Experimental and clinical studies have shown that the neurological deficits associated with SBA are not simply caused by incomplete neurulation at the level of the lesion. Read More

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Deliberate self-poisoning by teenagers.

Arch Dis Child 2018 Jul 11. Epub 2018 Jul 11.

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Hypothermia for perinatal asphyxia: trial-based resource use and costs at 6-7 years.

Arch Dis Child Fetal Neonatal Ed 2018 Jul 11. Epub 2018 Jul 11.

Nuffield Department of Population Health, National Perinatal Epidemiology Unit (NPEU), University of Oxford, Oxford, UK.

Objective: To assess the impact of hypothermic neural rescue for perinatal asphyxia at birth on healthcare costs of survivors aged 6-7 years, and to quantify the relationship between costs and overall disability levels.

Design: 6-7 years follow-up of surviving children from the Total Body Hypothermia for Neonatal Encephalopathy (TOBY) trial.

Setting: Community study including a single parental questionnaire to collect information on children's healthcare resource use. Read More

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Time interval for preterm infant weight gain velocity calculation precision.

Arch Dis Child Fetal Neonatal Ed 2018 Jul 11. Epub 2018 Jul 11.

Biomedical Institute of New Jersey and MidAtlantic Neonatal Associates, Morriston, New Jersey, USA.

Calculation of weight gain velocity is used to guide nutrition and fluid management practices in neonatal intensive care units. Calculations over short time periods may be more responsive to management changes, but less precise. Weight gain velocity calculated over 5 to 7+ days have lower variability and less noise than shorter periods. Read More

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July 2018
2 Reads

Saddle embolism in an extremely premature infant.

Arch Dis Child Fetal Neonatal Ed 2018 Jul 11. Epub 2018 Jul 11.

Division of Pediatric Cardiology, University of South Alabama, Mobile, Alabama, USA.

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Clinically effective implementation of intravenous paracetamol as primary analgesia after major surgery in neonates and young infants.

Arch Dis Child 2018 Jul 10. Epub 2018 Jul 10.

Intensive Care and Pediatric Surgery, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.

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What do I need to know about fluoroquinolones for children?

Arch Dis Child Educ Pract Ed 2018 Jul 9. Epub 2018 Jul 9.

Department of Paediatrics and Medical Genetics, Ghent University Hospital, Gent, Belgium.

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Hanging and near hanging in children: injury patterns and a clinical approach to early management.

Arch Dis Child Educ Pract Ed 2018 Jul 9. Epub 2018 Jul 9.

Emergency Department, Birmingham Children's Hospital, Birmingham, UK.

Near hanging refers to survival following suspension by the neck. This is a devastating injury which can lead to mortality or serious long-term morbidity. Children and young people present to emergency departments following accidental or deliberate near hanging. Read More

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July 2018
1 Read

Multiplex PCR reveals a high prevalence of multiple pathogens in traveller's diarrhoea in children.

Arch Dis Child 2018 Jul 7. Epub 2018 Jul 7.

Microbiology Laboratory, Robert Debré Hospital, Paris, France.

Objective: Traveller's diarrhoea (TD) is one of the most frequent illnesses affecting children returning from tropical countries. The purpose of this study was to assess the distribution of pathogens associated with TD in children using a multiplex PCR assay on stool samples.

Design: All the children admitted for TD in two university hospitals from 1 August to 15October during 2014 and 2015 were included in a prospective study. Read More

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Is mid-upper arm circumference in Dutch children useful in identifying obesity?

Arch Dis Child 2018 Jul 7. Epub 2018 Jul 7.

Department Public and Occupational Health, Amsterdam Public Health, Child Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands.

Background: Mid-upper arm circumference (MUAC) is suggested as being a valid measure in detecting overweight/obesity in children and adolescents, due to the strong relation with weight. We examined this relation and compared MUAC to body mass index (BMI) according to the International Obesity Task Force (IOTF) in children.

Methods: Anthropometric data including MUAC were collected in 2009 by trained healthcare professionals in the context of the fifth Dutch Nationwide Growth Study, in a sample of 6167 children (2891 boys and 3276 girls) aged 2-18 years of Dutch origin. Read More

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Family integrated care: what's all the fuss about?

Arch Dis Child Fetal Neonatal Ed 2018 Jul 6. Epub 2018 Jul 6.

Neonatology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

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Outcomes after admission on weekend day compared with weekday.

Authors:
Steve Turner

Arch Dis Child 2018 Jul 6. Epub 2018 Jul 6.

Department of Child Health, Royal Aberdeen Children's Hospital, Aberdeen, UK.

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Comparing the usability of paediatric weight estimation methods: a simulation study.

Arch Dis Child 2018 Jul 5. Epub 2018 Jul 5.

Paediatric Emergency Department, Bristol Royal Children's Hospital, Bristol, UK.

Objective: Estimating weight is essential in order to prepare appropriate sized equipment and doses of resuscitation drugs in cases where children are critically ill or injured. Many methods exist with varying degrees of complexity and accuracy. The most recent version of the Advanced Paediatric Life Support (APLS) course has changed their teaching from an age-based calculation method to the use of a reference table. Read More

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Stem cell-based therapies in neonatology: a new hope.

Authors:
Bernard Thébaud

Arch Dis Child Fetal Neonatal Ed 2018 Jul 4. Epub 2018 Jul 4.

Regenerative Medicine Program, Sinclair Centre for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

Despite progress made in neonatal intensive care, complications of extreme preterm birth still contribute as the main cause of death to children below 5 years of age. Stem cell-based therapies-mesenchymal stromal cells in particular-offer a new hope in preventing and/or restoring organ damage in extreme preterm infants. Early phase clinical trials, fueled by promising preclinical studies on lung and brain injury, have begun. Read More

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July 2018
2 Reads

Point-of-care lung ultrasonography for pneumonia in children: does size really matter?

Authors:
Aaron E Chen

Arch Dis Child 2018 Jul 4. Epub 2018 Jul 4.

Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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Painful swelling of the clavicle.

Arch Dis Child Educ Pract Ed 2018 Jul 4. Epub 2018 Jul 4.

Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.

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Supplementation in hypophosphataemic rickets: the bare bones of management.

Arch Dis Child Educ Pract Ed 2018 Jul 3. Epub 2018 Jul 3.

Paediatrics, Poole Hospital NHS Trust, Poole, UK.

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Fifteen-minute consultation: Management of the upper limb in unilateral cerebral palsy.

Arch Dis Child Educ Pract Ed 2018 Jul 3. Epub 2018 Jul 3.

Paediatric Neurology, Great North Children's Hospital, Newcastle upon Tyne, UK.

Children with unilateral cerebral palsy (UCP) have complex health, education and social care needs. Delayed gross motor milestones are the most common presenting feature, and much of the early management focuses on gross motor skills and lower limb management. In later childhood, adolescence and adulthood, upper limb function has significant impact on activity, participation and independence. Read More

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July 2018
1 Read

Subcutaneous fat necrosis in a neonate.

Arch Dis Child Educ Pract Ed 2018 Jul 3. Epub 2018 Jul 3.

Paediatrics, Oxford University Hospitals NHS Foundation Trust , Horton General Hospital, Banbury, UK.

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Medical needs of adolescent refugees resettling in Western Australia.

Arch Dis Child 2018 Jul 3. Epub 2018 Jul 3.

Division of Paediatrics, School of Medicine, University of Western Australia, Perth, Western Australia, Australia.

Objective: To investigate the medical needs and socioeconomic determinants of health among adolescent refugees resettling in Western Australia.

Design: Comprehensive medical and socioeconomic health data of resettling adolescent refugees aged 12 years and above attending a Refugee Health Service over a 1-year period were analysed.

Results: Medical records of 122 adolescents, median (range) age of 14 (12-17) years, were reviewed. Read More

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Functional outcome in contemporary children and young adults with tetralogy of Fallot after repair.

Arch Dis Child 2018 Jul 3. Epub 2018 Jul 3.

Institute of Preventive Pediatrics, Technische Universität München, Munich, Germany.

Objective: Functional outcome measures are of growing importance in the aftercare of patients with congenital heart disease. This study addresses the functional status with regard to exercise capacity, health-related physical fitness (HRPF) and arterial stiffness in a recent cohort of children, adolescents and young adults with tetralogy of Fallot (ToF) after repair.

Design: Single-centre, uncontrolled and prospective cohort study. Read More

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July 2018
3 Reads

Physical growth, neurodevelopment and cognition outcomes in children with abdominal wall defects: a tale with two endings?

Arch Dis Child Fetal Neonatal Ed 2018 Jul 2. Epub 2018 Jul 2.

Douglas Cohen Department of Paediatric Surgery, The Children's Hospital at Westmead, The University of Sydney, Sydney, New South Wales, Australia.

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Routine micturating cystourethrogram for multicystic dysplastic kidneys: have we moved on?

Arch Dis Child 2018 Jul 2. Epub 2018 Jul 2.

The Shrewsbury and Telford Hospital NHS Trust, Princess Royal Hospital, Telford, UK.

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Pulmonary renal syndrome in Henoch-Schönlein purpura.

Arch Dis Child 2018 Jul 2. Epub 2018 Jul 2.

Department of Paediatric Rheumatology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.

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Quality of life of extremely preterm school-age children without major handicap: a cross-sectional observational study.

Arch Dis Child 2018 Jun 30. Epub 2018 Jun 30.

Public Health Department-Research Unit EA3279, Aix-Marseille University, Marseille, France.

Objective: To determine the quality of life (QoL) of school-aged children who were born <28 weeks of gestation and who have no resultant major disabilities.

Design, Setting And Patients: A cross-sectional multicentre study of extremely preterm (EPT) infants born <28 weeks, discharged alive and free from severe impairments (cerebral palsy, autism, major cognitive disabilities). Two generic, self-evaluation and hetero-evaluation (by parent) QoL measurement questionnaires (Kidscreen 10/VSP-A) were used and then compared with French population reference. Read More

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June 2018
1 Read

Is obesity associated with depression in children? Systematic review and meta-analysis.

Arch Dis Child 2018 Jun 29. Epub 2018 Jun 29.

Department of Primary Care and Public Health, Imperial College London, London, UK.

Objectives: To compare the odds of depression in obese and overweight children with that in normal-weight children in the community.

Design: Systematic review and random-effect meta-analysis of observational studies.

Data Sources: EMBASE, PubMed and PsychINFO electronic databases, published between January 2000 and January 2017. Read More

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Limping in children: look what the cat dragged in!

Arch Dis Child 2018 Jun 29. Epub 2018 Jun 29.

Pediatric Infectious Disease, Department of Paediatrics, Centre Hospitalier Chrétien (CHC), Clinique de l'Espérance, Liège, Belgium.

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T-piece resuscitators: a warning sign.

Arch Dis Child Fetal Neonatal Ed 2018 Jun 28. Epub 2018 Jun 28.

Division of Neonatal Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.

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June 2018
2 Reads

Epidemiology of infections and antimicrobial use in Greek Neonatal Units.

Arch Dis Child Fetal Neonatal Ed 2018 Jun 28. Epub 2018 Jun 28.

Department of Paediatrics, Patras Medical School, University Hospital of Patras, Patras, Greece.

Objective: To describe the epidemiology of neonatal infections and of antimicrobial use in Greek Neonatal Units (NNUs) in order to develop national, evidence-based guidelines on empiric antimicrobial use for neonatal sepsis in Greece.

Design: Retrospective analysis of prospectively collected infection surveillance data from 2012 to 2015, together with a Point Prevalence Survey (PPS) on antimicrobial use and the collection of data on local empiric antimicrobial policies.

Setting: 16 NNUs in Greece participating in the neonIN infection surveillance network PATIENTS: Newborns in participating NNUs who had a positive blood, cerebrospinal fluid or urine culture and were treated with at least 5 days of antibiotics. Read More

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June 2018
1 Read

Breastfeeding outcomes in European NICUs: impact of parental visiting policies.

Arch Dis Child Fetal Neonatal Ed 2018 Jun 28. Epub 2018 Jun 28.

Obstetrical, Perinatal and Pediatric Epidemiology Research Team, Centre for Epidemiology and Biostatistics (U1153), Inserm UMR 1153, Paris, France.

Objective: The documented benefits of maternal milk for very preterm infants have raised interest in hospital policies that promote breastfeeding. We investigated the hypothesis that more liberal parental policies are associated with increased breastfeeding at discharge from the neonatal unit.

Design: Prospective area-based cohort study. Read More

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June 2018
1 Read

Extending non-invasive prenatal testing to non-invasive prenatal diagnosis.

Arch Dis Child Fetal Neonatal Ed 2018 Jun 28. Epub 2018 Jun 28.

Wessex Clinical Genetics Service, G Level, Princess Anne Hospital, Southampton, UK.

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Lived experience of Silver-Russell syndrome: implications for management during childhood and into adulthood.

Arch Dis Child 2018 Jun 28. Epub 2018 Jun 28.

Faculty of Medicine, Clinical Ethics and Law, University of Southampton, Southampton, UK.

Objective: There is limited information on the psychosocial impact of growing up with Silver-Russell syndrome (SRS), characterised by slow growth in utero leading to short stature in adulthood. Such information could aid families in making difficult treatment decisions and guide management strategies for health professionals. We aimed to explore the lived experience of people with SRS across the lifespan. Read More

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What are you looking at?

Authors:
Damian Roland

Arch Dis Child 2018 Jun 28. Epub 2018 Jun 28.

SAPPHIRE Group, Health Sciences, Centre for Medicine, University of Leicester, Leicester, UK.

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Davener's dermatosis.

Arch Dis Child 2018 Jun 27. Epub 2018 Jun 27.

Dermatology Service, KK Women's and Children's Hospital, Singapore.

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Vitamin D intake for preterm infants: how much do they really need?

Arch Dis Child 2018 Jun 27. Epub 2018 Jun 27.

Neonatology, Our Lady's Children's Hospital, Dublin, Ireland.

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Utility of proactive infliximab levels in paediatric Crohn's disease.

Arch Dis Child 2018 Jun 27. Epub 2018 Jun 27.

Department of Gastroenterology, Hepatology and Liver Transplant, Lady Cilento Children's Hospital, South Brisbane, Queensland, Australia.

Objective: Infliximab (IFX) has an established role in Crohn's disease (CD), with serum trough levels of IFX (TLI) increasingly used to optimise dosing. We report the utility of routine, proactive TLI in children on combination therapy with immunosuppression (IS) from a single paediatric centre.

Methods: This is a retrospective chart review of all children with CD receiving IFX therapy conducted betweenJanuary 2014-May 2017. Read More

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June 2018
2 Reads

'Corkscrews' on the patchy alopecia of a girl.

Arch Dis Child Educ Pract Ed 2018 Jun 27. Epub 2018 Jun 27.

Department of Dermatology, Venereology, and Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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Gastrointestinal sequelae after surgery for necrotising enterocolitis: a systematic review and meta-analysis.

Arch Dis Child Fetal Neonatal Ed 2018 Jun 26. Epub 2018 Jun 26.

Department of Pediatric Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Objectives: To document what types of gastrointestinal sequelae were described after surgery for necrotising enterocolitis (NEC) and to analyse their frequency.

Design: Systematic review and meta-analysis.

Data Sources: Medline, EMBASE and the Cochrane library (CENTRAL) from 1990 to October 2016. Read More

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Fifteen-minute consultation: Childhood burns: inflicted, neglect or accidental.

Arch Dis Child Educ Pract Ed 2018 Jun 22. Epub 2018 Jun 22.

Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.

Burns are a relatively common injury in children accounting for over 50 000 emergency department attendances each year. An estimated 1 in 10 of these are due to maltreatment. These may present in the form of physical abuse or neglect with a reported ratio of 1:9. Read More

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