3,534 results match your criteria Archives of Disease in Childhood: Fetal and Neonatal Edition[Journal]


Validation of the disposable T-piece resuscitator (Neo-Tee): a bench study.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 19. Epub 2019 Feb 19.

Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Objective: The Neo-Tee Infant T-piece resuscitator is a disposable T-piece resuscitator. The aim of this bench study was to assess the accuracy of the Neo-Tee using a measurement set-up and settings mimicking clinical practice.

Study Design: Nine Neo-Tee devices were tested using a face mask interface and a manikin. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315298DOI Listing
February 2019

UK survey of less invasive surfactant administration.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 11. Epub 2019 Feb 11.

Department of Women and Children's Health, School of Life Sciences, Faculty of Life Science and Medicine, King's College London, London, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316466DOI Listing
February 2019
3 Reads

Current clinical practice in neonatologist-performed echocardiography in the UK.

Authors:
Yogen Singh

Arch Dis Child Fetal Neonatal Ed 2019 Feb 8. Epub 2019 Feb 8.

Neonatology/Paediatric Cardiology, Addenbrooke's, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316348DOI Listing
February 2019

Neonatal cardiopulmonary transition in an ovine model of congenital diaphragmatic hernia.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 6. Epub 2019 Feb 6.

The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria, Australia.

Objective: Infants with a congenital diaphragmatic hernia (CDH) are at high risk of developing pulmonary hypertension after birth, but little is known of their physiological transition at birth. We aimed to characterise the changes in cardiopulmonary physiology during the neonatal transition in an ovine model of CDH.

Methods: A diaphragmatic hernia (DH) was surgically created at 80 days of gestational age (dGA) in 10 fetuses, whereas controls underwent sham surgery (n=6). Read More

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http://dx.doi.org/10.1136/archdischild-2018-316045DOI Listing
February 2019
3 Reads

New short-term heat inactivation method of cytomegalovirus (CMV) in breast milk: impact on CMV inactivation, CMV antibodies and enzyme activities.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 6. Epub 2019 Feb 6.

Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital of Tuebingen, Tubingen, Germany.

Objectives: Breast milk (BM) is the primary source of cytomegalovirus (CMV) transmission to premature infants with potentially harmful consequences. We therefore wanted to evaluate temperature and duration of short-term BM pasteurisation with respect to CMV inactivation, effect on CMV-IgG antibodies and BM enzyme activities.

Methods: 116 artificially CMV-spiked BM and 15 wild-type virus-infected samples were subjected for 5 s to different temperatures (55°C-72°C). Read More

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http://dx.doi.org/10.1136/archdischild-2018-316117DOI Listing
February 2019
1 Read

Effects of tracheal occlusion on the neonatal cardiopulmonary transition in an ovine model of diaphragmatic hernia.

Arch Dis Child Fetal Neonatal Ed 2019 Feb 6. Epub 2019 Feb 6.

The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria, Australia.

Objective: Fetoscopic endoluminal tracheal occlusion (FETO) aims to reverse pulmonary hypoplasia associated with congenital diaphragmatic hernia (CDH) and mitigate the associated respiratory insufficiency and pulmonary hypertension after birth. We aimed to determine whether FETO improves the cardiopulmonary transition at birth in an ovine model of CDH.

Methods: In 12 ovine fetuses with surgically induced diaphragmatic hernia (DH; 80 dGA), an endotracheal balloon was placed tracheoscopically at ≈110 dGA and removed at ≈131 dGA (DH+FETO), while 10 were left untreated (DH). Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31604
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http://dx.doi.org/10.1136/archdischild-2018-316047DOI Listing
February 2019
2 Reads

Can we estimate the length of stay of very preterm multiples?

Arch Dis Child Fetal Neonatal Ed 2019 Feb 2. Epub 2019 Feb 2.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316321DOI Listing
February 2019

Intrathoracic renal ectopia with congenital diaphragmatic hernia.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13. Epub 2019 Jan 13.

Neonatal Intensive Care Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31619
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http://dx.doi.org/10.1136/archdischild-2018-316195DOI Listing
January 2019
7 Reads

Parental smoking and support in the NICU.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13. Epub 2019 Jan 13.

Norwich Medical School, University of East Anglia, Norwich, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316413DOI Listing
January 2019
1 Read

Perinatal palliative care: a national survey in Italy.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13. Epub 2019 Jan 13.

Neonatal Intensive Care Unit, Department of Woman's and Child's Health, University of Padua, Padua, Italy.

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http://dx.doi.org/10.1136/archdischild-2018-316327DOI Listing
January 2019
1 Read

Respiratory monitors to teach newborn facemask ventilation: a randomised trial.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13. Epub 2019 Jan 13.

Newborn Research Centre, The Royal Women's Hospital, Parkville, Victoria, Australia.

Objective: The International Liaison Committee on Resuscitation has found that there is a need for high-quality randomised trials of training interventions that improve the effectiveness of resuscitation skills. The objective of this study was to determine whether using a respiratory function monitor (RFM) during mask ventilation training with a manikin reduces facemask leak.

Design: Stratified, parallel-group, randomised controlled trial. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31611
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http://dx.doi.org/10.1136/archdischild-2018-316118DOI Listing
January 2019
5 Reads

Comparison of conventional and videolaryngoscopy blades in neonates.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 3. Epub 2019 Jan 3.

Neonatal Intensive Care Unit, Royal Hospital for Children Glasgow, Glasgow, UK.

Neonatal intubation is an essential but difficult skill to learn. Videolaryngoscopy allows the airway view to be shared by the intubator and supervisor and improves intubation success. Ideally, a videolaryngoscope (VL) should be usable as a conventional laryngoscope (CL). Read More

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http://dx.doi.org/10.1136/archdischild-2018-315644DOI Listing
January 2019
1 Read

Neonatal cutaneous lupus erythematosus.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 22;104(2):F191. Epub 2018 Dec 22.

Department of Neonatology and Pediatrics, Complexo Hospitalario Universitario de A Coruña, A Coruña, Spain.

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http://dx.doi.org/10.1136/archdischild-2018-316147DOI Listing
March 2019
1 Read

Therapeutic hypothermia for mild neonatal encephalopathy: a systematic review and meta-analysis.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 19. Epub 2018 Dec 19.

Centre for Perinatal Neuroscience, Imperial College London, London, UK.

Objectives: To examine if therapeutic hypothermia reduces the composite outcome of death, moderate or severe disability at 18 months or more after mild neonatal encephalopathy (NE).

Data Source: MEDLINE, Cochrane database, Scopus and ISI Web of Knowledge databases, using 'hypoxic ischaemic encephalopathy', 'newborn' and 'hypothermia', and 'clinical trials' as medical subject headings and terms. Manual search of the reference lists of all eligible articles and major review articles and additional data from the corresponding authors of selected articles. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31571
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http://dx.doi.org/10.1136/archdischild-2018-315711DOI Listing
December 2018
21 Reads

Assessment of resistance of nasal continuous positive airway pressure interfaces.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 19. Epub 2018 Dec 19.

Monash Newborn, Monash Medical Centre, Clayton, Victoria, Australia.

Objective: To compare the resistance of interfaces used for the delivery of nasal continuous positive airway pressure (CPAP) in neonates, as measured by the generated system pressure at fixed gas flows, in an in vitro setting.

Design: Gas flows of 6, 8 and 10 L/min were passed through three sizes of each of a selection of available neonatal nasal CPAP interfaces (Hudson prong, RAM Cannula, Fisher & Paykel prong, Infant Flow prong, Fisher & Paykel mask, Infant Flow mask). The expiratory limb was occluded and pressure differential measured using a calibrated pressure transducer. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31583
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http://dx.doi.org/10.1136/archdischild-2018-315838DOI Listing
December 2018
8 Reads

Neonatal orbital swelling due to intracranial teratoma.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 14. Epub 2018 Dec 14.

Department of Paediatric Medicine, KK Women's and Children's Hospital, Singapore, Singapore.

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31633
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http://dx.doi.org/10.1136/archdischild-2018-316337DOI Listing
December 2018
6 Reads

Understanding the principle biophysics concepts of pulmonary surfactant in health and disease.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 14. Epub 2018 Dec 14.

Department of Biochemistry and Molecular Biology, Faculty of Biology, Complutense University, Madrid, Spain.

Pulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate structure of mammalian alveoli along with successive compression-expansion respiratory cycles. To do so, surfactant reduces dramatically surface tension at the air-liquid interface, an activity that depends critically on a proper lipid composition and the presence of some specific surfactant proteins. Lack or dysfunction of this system is associated with severe respiratory pathologies, which are in some cases treated by supplementation with exogenous surfactant materials. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315413DOI Listing
December 2018
1 Read

Milk feed osmolality and adverse events in newborn infants and animals: a systematic review.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 6. Epub 2018 Dec 6.

Danone Nutricia Research, Utrecht, The Netherlands.

Background: High feed osmolality (or osmolarity) is often suggested to be linked with adverse gastrointestinal events in preterm infants.

Aim: To systematically review the literature on milk feed osmolality and adverse gastrointestinal events in newborn and low birthweight infants and animals.

Methods: MEDLINE, Embase, CAB Abstracts, Current Contents, BIOSIS Previews and SciSearch were searched from inception to May 2018 to identify potentially relevant studies. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315946DOI Listing
December 2018
3 Reads
3.120 Impact Factor

Appraisal of a scoring instrument for training and testing neonatal intubation skills.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 1. Epub 2018 Dec 1.

Department of Neonatology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.

Objective: To determine the validity, reliability, feasibility and applicability of a neonatal intubation scoring instrument.

Design: Prospective observational study.

Setting: Simulation-based research and training centre (Center for Advanced Pediatric and Perinatal Education), California, USA. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31522
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http://dx.doi.org/10.1136/archdischild-2018-315221DOI Listing
December 2018
7 Reads

Benefits of recording and reviewing neonatal resuscitation: the providers' perspective.

Arch Dis Child Fetal Neonatal Ed 2018 Dec 1. Epub 2018 Dec 1.

Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands.

Objective: To assess benefits of recording and reviewing neonatal resuscitation as experienced by neonatal care providers.

Design: A qualitative study using semistructured interviews questioning neonatal care providers about their experiences with recording and reviewing neonatal resuscitation. Data were analysed using the qualitative data analysis software Atlas. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315648DOI Listing
December 2018
2 Reads

Establishing a composite neonatal adverse outcome indicator using English hospital administrative data.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 28. Epub 2018 Nov 28.

Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, UK.

Objective: We adapted a composite neonatal adverse outcome indicator (NAOI), originally derived in Australia, and assessed its feasibility and validity as an outcome indicator in English administrative hospital data.

Design: We used Hospital Episode Statistics (HES) data containing information infants born in the English National Health Service (NHS) between 1 April 2014 and 31 March 2015. The Australian NAOI was mapped to diagnoses and procedure codes used within HES and modified to reflect data quality and neonatal health concerns in England. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31514
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http://dx.doi.org/10.1136/archdischild-2018-315147DOI Listing
November 2018
4 Reads

EEG for the assessment of neurological function in newborn infants immediately after birth.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 26. Epub 2018 Nov 26.

Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.

Objective: To assess the neurological function of newborn infants in the first minutes after birth using EEG.

Design And Patients: We obtained electroencephalography (EEG) recordings in term infants following elective caesarean section. After delivery, disposable EEG electrodes were attached to the infants' scalp over the frontal and central regions bilaterally and EEG was recorded for 10 min. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315231DOI Listing
November 2018
2 Reads

Staff matter too: pilot staff support intervention to reduce stress and burn-out on a neonatal intensive care unit.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 26. Epub 2018 Nov 26.

Neonatal Intensive Care Unit, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316217DOI Listing
November 2018
1 Read

Accuracy of real-time delivery room resuscitation documentation.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 24. Epub 2018 Nov 24.

Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

Objective: To assess the accuracy of real-time delivery room resuscitation documentation.

Design: Retrospective observational study.

Setting: Level 3 academic neonatal intensive care unit. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31572
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http://dx.doi.org/10.1136/archdischild-2018-315723DOI Listing
November 2018
2 Reads

Characterisation of neonatal seizures and their treatment using continuous EEG monitoring: a multicentre experience.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 24. Epub 2018 Nov 24.

Irish Centre for Fetal and Neonatal Translational Research (INFANT), Cork, Ireland.

Objective: The aim of this multicentre study was to describe detailed characteristics of electrographic seizures in a cohort of neonates monitored with multichannel continuous electroencephalography (cEEG) in 6 European centres.

Methods: Neonates of at least 36 weeks of gestation who required cEEG monitoring for clinical concerns were eligible, and were enrolled prospectively over 2 years from June 2013. Additional retrospective data were available from two centres for January 2011 to February 2014. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315624DOI Listing
November 2018
12 Reads

Social gradient of birthweight in England assessed using the INTERGROWTH-21 gestational age-specific standard.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 21. Epub 2018 Nov 21.

Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.

Objective: To determine the socioeconomic gradient of birthweights in England with reference to the prescriptive INTERGROWTH-21 Birthweight Standard.

Design: National cross-sectional study using data from Hospital Episode Statistics.

Setting: National Health Service in England. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315295DOI Listing
November 2018
13 Reads

Randomised cross-over study of automated oxygen control for preterm infants receiving nasal high flow.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 21. Epub 2018 Nov 21.

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Objective: To evaluate a prototype automated controller (IntellO) of the inspired fraction of oxygen (FiO) in maintaining a target range of oxygen saturation (SpO) in preterm babies receiving nasal high flow (HF) via the Vapotherm Precision Flow.

Design: Prospective two-centre order-randomised cross-over study.

Setting: Neonatal intensive care units. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315342DOI Listing
November 2018
15 Reads

Current use of probiotics to prevent necrotising enterocolitis.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 21;104(2):F228. Epub 2018 Nov 21.

Neonatal Unit, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316199DOI Listing
March 2019
9 Reads

Premature small for gestational age infants fed an exclusive human milk-based diet achieve catch-up growth without metabolic consequences at 2 years of age.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Section of Neonatology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA.

Objective: To compare postdischarge growth, adiposity and metabolic outcomes of appropriate for gestational age (AGA) versus small for gestational age (SGA) premature infants fed an exclusive human milk (HM)-based diet in the neonatal intensive care unit.

Design: Premature infants (birth weight ≤1250 g) fed an exclusive HM-based diet were examined at 12-15 months corrected gestational age (CGA) (visit 1) for anthropometrics, serum glucose and non-fasting insulin, and at 18-22 months CGA (visit 2) for body composition by dual-energy X-ray absorptiometry.

Results: Of 51 children, 33 were AGA and 18 were SGA at birth. Read More

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http://dx.doi.org/10.1136/archdischild-2017-314547DOI Listing
November 2018
1 Read

Network meta-analysis explained.

Arch Dis Child Fetal Neonatal Ed 2019 Jan 13;104(1):F8-F12. Epub 2018 Nov 13.

Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/archdischild-2018-315224DOI Listing
January 2019
1 Read

Randomised study comparing heart rate measurement in newly born infants using a monitor incorporating electrocardiogram and pulse oximeter versus pulse oximeter alone.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

National Maternity Hospital, Dublin, Ireland.

Aim: To determine whether IntelliVue (ECG plus Masimo pulse oximeter (PO)) measures heart rate (HR) in low-risk newborns more quickly than Nellcor PO (PO alone).

Methods: Unmasked parallel group randomised (1:1) study.

Results: We studied 100 infants, 47 randomised to IntelliVue, 53 to Nellcor. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2017-31436
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http://dx.doi.org/10.1136/archdischild-2017-314366DOI Listing
November 2018
10 Reads

Therapeutic hypothermia initiated within 6 hours of birth is associated with reduced brain injury on MR biomarkers in mild hypoxic-ischaemic encephalopathy: a non-randomised cohort study.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Centre for Perinatal Neuroscience, Imperial College London, London, UK.

Objective: To examine the effect of therapeutic hypothermia on MR biomarkers and neurodevelopmental outcomes in babies with mild hypoxic-ischaemic encephalopathy (HIE).

Design: Non-randomised cohort study.

Setting: Eight tertiary neonatal units in the UK and the USA. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31604
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http://dx.doi.org/10.1136/archdischild-2018-316040DOI Listing
November 2018
23 Reads

Epidemiology and healthcare factors associated with neonatal enterococcal infections.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.

Objective: To investigate the epidemiology and healthcare factors associated with late-onset neonatal enterococcal infections.

Design: Multicentre, multinational retrospective cohort study using prospectively collected infection data from a neonatal infection surveillance network between 2004 and 2016; this was supplemented with healthcare data from a questionnaire distributed to participating neonatal units.

Setting: Sixty neonatal units across Europe (UK, Greece, Estonia) and Australia. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31538
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http://dx.doi.org/10.1136/archdischild-2018-315387DOI Listing
November 2018
13 Reads

Continuous glucose monitoring in the neonatal intensive care unit: not quite ready for 'plug and play'.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Department of Pediatrics, Perinatal Research Center, University of Colorado School of Medicine, Aurora, Colorado, USA.

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http://dx.doi.org/10.1136/archdischild-2018-315899DOI Listing
November 2018
2 Reads

Challenges and opportunities for antibiotic stewardship among preterm infants.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 13. Epub 2018 Nov 13.

Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Antibiotic stewardship programmes aim to optimise antimicrobial use to prevent the emergence of resistance species and protect patients from the side effects of unnecessary medication. The high incidence of systemic infection and associated mortality from these infections leads neonatal providers to frequently initiate antibiotic therapy and make empiric antibiotic courses one of the main contributors of antibiotic use in the neonatal units. Yet, premature infants are also at risk for acute life-threatening complications associated with antibiotic use such as necrotising enterocolitis and for long-term morbidities such as asthma. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31541
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http://dx.doi.org/10.1136/archdischild-2018-315412DOI Listing
November 2018
16 Reads

Cerebral autoregulation in premature infants during the first 96 hours of life and relationship to adverse outcomes.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 1. Epub 2018 Nov 1.

Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Objective: To test the hypothesis that impaired cerebral autoregulation (ICA) increases the susceptibility of premature infants to adverse outcomes, we determined the relationship of ICA and cerebral reactivity (CR) measured in the first 96 hours of life to the outcome of grade 3 or 4 intraventricular haemorrhage (IVH) and/or death within 1 month.

Setting: Single-centre level IV neonatal intensive care unit.

Patients: Neonates 24-29 weeks' gestation less than 12 hours old with invasive blood pressure monitoring. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315725DOI Listing
November 2018
2 Reads

Point-of-care measurements of blood ketones in newborns.

Arch Dis Child Fetal Neonatal Ed 2018 Nov 1. Epub 2018 Nov 1.

Liggins Institute, University of Auckland, Auckland, New Zealand.

Objective: Babies may use alternative cerebral fuels including ketones when blood glucose concentrations are low, but laboratory ketone measurements are slow and expensive. Point-of-care measurement of ketone concentrations, if sufficiently accurate, may provide useful information for clinical care.

Patients And Design: Eligible babies were 35-42 weeks' gestation, ≤10 days old and admitted to the newborn intensive care unit. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31629
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http://dx.doi.org/10.1136/archdischild-2018-316293DOI Listing
November 2018
14 Reads

UK neonatal resuscitation survey.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 24. Epub 2018 Oct 24.

Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.

Background: Previous surveys have demonstrated that neonatal resuscitation practices on the delivery suite vary between UK units, particularly according to the hospital's neonatal unit's level. Our aim was to determine if recent changes to the Resuscitation Council guidelines had influenced clinical practice.

Methods: Surveys of resuscitation practices at UK delivery units carried out in 2012 and 2017 were compared. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31552
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http://dx.doi.org/10.1136/archdischild-2018-315526DOI Listing
October 2018
2 Reads

Cerebrovascular autoregulation in preterm fetal growth restricted neonates.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 24. Epub 2018 Oct 24.

Department of Neonatology, Wilhelmina Children's Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands.

Objective: To investigate the effect of fetal growth restriction (FGR) on cerebrovascular autoregulation in preterm neonates during the first 3 days of life.

Design: Case-control study.

Setting: Neonatal intensive care unit of the Wilhelmina Children's Hospital, The Netherlands. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2017-31371
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http://dx.doi.org/10.1136/archdischild-2017-313712DOI Listing
October 2018
7 Reads

Beta blocker therapy in recipients of twin-to-twin transfusion syndrome.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 24. Epub 2018 Oct 24.

Department of Neonatology, Children's University Hospital, Tuebingen, Germany.

Recipients of severe twin-to-twin transfusion syndrome (TTTS) may suffer from low cardiac output caused by myocardial hypertrophy and sudden postnatal drop in preload. Our hypothesis was that selective beta-1 adrenergic blockers improve cardiac function in TTTS recipients with left ventricular outflow tract obstruction. We analysed data from two TTTS recipients treated with esmolol/metoprolol. Read More

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http://dx.doi.org/10.1136/archdischild-2017-314497DOI Listing
October 2018
3 Reads

Assessment of neonatal heart rate immediately after birth using digital stethoscope, handheld ultrasound and electrocardiography: an observational cohort study.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 24;104(2):F227. Epub 2018 Oct 24.

Department of Neonatology, Coombe Women and Infants University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1136/archdischild-2018-315619DOI Listing
March 2019
1 Read

It is time to standardise the length of postnatal antibiotic administration nationally.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 24;104(2):F225-F226. Epub 2018 Oct 24.

Medical School, Imperial College Medical School, London, UK.

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http://dx.doi.org/10.1136/archdischild-2018-316103DOI Listing
March 2019
1 Read

Newborn self-inflating manual resuscitators: precision robotic testing of safety and reliability.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 18. Epub 2018 Oct 18.

Neonatal Intensive Care Unit, Westmead Hospital, Westmead, New South Wales, Australia.

Aim: A controlled bench test was undertaken to determine the performance variability among a range of neonatal self-inflating bags (SIB) compliant with current International Standards Organisation (ISO).

Introduction: Use of SIB to provide positive pressure ventilation during newborn resuscitation is a common emergency procedure. The United Nations programmes advocate increasing availability of SIB in low-income and middle-income nations and recommend devices compliant with ISO. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31539
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http://dx.doi.org/10.1136/archdischild-2018-315391DOI Listing
October 2018
7 Reads

Proton magnetic resonance spectroscopy lactate/N-acetylaspartate within 2 weeks of birth accurately predicts 2-year motor, cognitive and language outcomes in neonatal encephalopathy after therapeutic hypothermia.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 15. Epub 2018 Oct 15.

Institute for Women's Health, University College London, London, UK.

Objective: Brain proton (H) magnetic resonance spectroscopy (MRS) lactate/N-acetylaspartate (Lac/NAA) peak area ratio is used for prognostication in neonatal encephalopathy (NE). At 3 Tesla in NE babies, the objectives were to assess: (1) sensitivity and specificity of basal ganglia and thalamus (BGT) H MRS Lac/NAA for the prediction of Bayley III outcomes at 2 years using optimised metabolite fitting (Tarquin) with threonine and total NAA; (2) prediction of motor outcome with diffusion-weighted MRI; (3) BGT Lac/NAA correlation with the National Institute of Child Health and Human Development (NICHD) MRI score.

Subjects And Methods: 55 (16 inborn, 39 outborn) infants at 39w+5 d (35w+5d-42w+0d) with NE admitted between February 2012 and August 2014 to University College London Hospitals for therapeutic hypothermia underwent MRI and H MRS at 3T on day 2-14 (median day 5). Read More

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http://dx.doi.org/10.1136/archdischild-2018-315478DOI Listing
October 2018
8 Reads

Optimising nutrition during therapeutic hypothermia.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 15. Epub 2018 Oct 15.

Section of Neonatal Medicine, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/archdischild-2018-315393DOI Listing
October 2018
3 Reads

Continuous infusion versus intermittent bolus doses of fentanyl for analgesia and sedation in neonates: an open-label randomised controlled trial.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 15. Epub 2018 Oct 15.

Department of Neonatology, Christian Medical College Vellore, Vellore, Tamil Nadu, India.

Objective: Adequate data on fentanyl pharmacokinetics in neonates are lacking. The study was performed to compare serum concentrations and clinical outcome between continuous infusion (CI) and intermittent bolus (IB) doses of fentanyl for analgesia and sedation in neonates.

Methods: In this open-label randomised controlled trial, neonates requiring 24-48 hours of mechanical ventilation and fentanyl administration were recruited. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31534
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http://dx.doi.org/10.1136/archdischild-2018-315345DOI Listing
October 2018
5 Reads
3.120 Impact Factor

Is preterm nutrition a trade-off between head and heart?

Arch Dis Child Fetal Neonatal Ed 2018 Oct 12. Epub 2018 Oct 12.

Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31567
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http://dx.doi.org/10.1136/archdischild-2018-315672DOI Listing
October 2018
11 Reads

Risk-adjusted mortality of VLBW infants in high-volume versus low-volume NICUs.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 8. Epub 2018 Oct 8.

Regional Office for Quality Assurance in Hospitals (GeQiK), Stuttgart, Germany.

Objective: To examine whether the number of very low birthweight (VLBW) infants treated annually in neonatal intensive care units (NICUs) (hospital volume) has an effect on their in-hospital mortality under the regulatory conditions in Germany.

Setting: The study included VLBW infants with <33 weeks of gestational age and birth weight below 1500 g admitted to NICUs in the state of Baden-Wüerttemberg, Germany, from 2003 to 2008. Cases were extracted from the compulsory German neonatal quality assurance programme with variables essential for calculation of the Clinical Risk Index for Babies (CRIB) and PREM birth model (PREM(bm)) scores. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31495
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http://dx.doi.org/10.1136/archdischild-2018-314956DOI Listing
October 2018
12 Reads

Physiological-based cord clamping in preterm infants using a new purpose-built resuscitation table: a feasibility study.

Arch Dis Child Fetal Neonatal Ed 2018 Oct 3. Epub 2018 Oct 3.

Division of Neonatology, Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands.

Objective: Physiological-based cord clamping (PBCC) led to a more stable cardiovascular adaptation and better oxygenation in preterm lambs, but in preterm infants, this approach has been challenging. Our aim was to assess the feasibility of PBCC, including patterns of oxygen saturation (SpO) and heart rate (HR) during stabilisation in preterm infants using a new purpose-built resuscitation table.

Design: Observational study. Read More

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31548
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http://dx.doi.org/10.1136/archdischild-2018-315483DOI Listing
October 2018
4 Reads

Meconial hydrocele as first sign of acute intestinal perforation in a preterm baby.

Arch Dis Child Fetal Neonatal Ed 2019 Mar 29;104(2):F169-F170. Epub 2018 Sep 29.

Department of Pediatric Surgery, University Hospital Son Espases, Palma de Mallorca, Spain.

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http://fn.bmj.com/lookup/doi/10.1136/archdischild-2018-31573
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http://dx.doi.org/10.1136/archdischild-2018-315737DOI Listing
March 2019
6 Reads