4,310 results match your criteria Archives of Dermatological Research[Journal]


Contrasting the efficacy of pulsed dye laser and photodynamic methylene blue nanoemulgel therapy in treating acne vulgaris.

Arch Dermatol Res 2020 May 24. Epub 2020 May 24.

Department of Dermatology, Electricity Hospital, Cairo, Egypt.

The treatment of acne remains a challenge for dermatologists. A variety of conventional therapies are available for acne treatment such as topical and systemic medications. Although many of these traditional acne treatments are effective, the wide-spread nature of the disease and its sometimes resistant nature delineate the need for alternative therapies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02093-yDOI Listing

Follow-up of skin lesions during the evolution of COVID-19: a case report.

Arch Dermatol Res 2020 May 14. Epub 2020 May 14.

Medical Faculty of Recife, Centro de Ciências Médicas, Federal University of Pernambuco, Av. da Engenharia, 531-611 - Cidade Universitária, Recife, 50730-120, PE, Brazil.

The disease caused by the new coronavirus (COVID-19) has many systemic manifestations affecting the upper airways, lungs, gastrointestinal tract and inducing hematological repercussions. With the evolution of the pandemic, skin lesions were observed. However, there is little information about the evolution of the lesions at this moment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02091-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221337PMC

Why it's hard to see a dermatologist for a skin exam: the patient perspective.

Arch Dermatol Res 2020 May 12. Epub 2020 May 12.

University Hospitals Cleveland Medical Center, 11100 Euclid Ave., Cleveland, OH, 44106, USA.

Background: In-office skin exams are recommended at least annually for patients who are diagnosed with a basal cell carcinoma or squamous cell carcinoma, but it is unknown what proportion of these patients are receiving skin exams. There are a multitude of reasons why patients have difficulty getting skin exams.

Aim: To assess the proportion of patients at our institution who received a skin exam in the 12 months following removal of a basal cell carcinoma or squamous cell carcinoma by Mohs micrographic surgery and to assess the barriers to care that patients faced in receiving a skin exam. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02080-3DOI Listing

Screening for cardiovascular comorbidity in United States outpatients with psoriasis, hidradenitis, and atopic dermatitis.

Arch Dermatol Res 2020 May 11. Epub 2020 May 11.

Department of Dermatology, George Washington University School of Medicine, 2150 Pennsylvania Avenue, Suite 2B-430, Washington, DC, 20037, USA.

Psoriasis, hidradenitis, and atopic dermatitis (AD) are associated with increased cardiometabolic comorbidities. Yet, little is known about screening rates for cardiometabolic comorbidities in patients with these disorders. The objective of this study is to determine rates and predictors of cardiovascular screening among patients with psoriasis, AD, and hidradenitis in the United States. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02087-wDOI Listing

Outpatient healthcare utilization and prescribing patterns for herpes zoster in United States adults.

Arch Dermatol Res 2020 May 10. Epub 2020 May 10.

Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Suite 2B-425, 2150 Pennsylvania Avenue, Washington, DC, 20037, USA.

Little is known about health resource utilization and treatment patterns for herpes zoster (HZV) after the introduction of HZV virus vaccination. The objective of this study is to characterize trends in HZV utilization, racial disparities, and treatment patterns in the United States. Data from the 1993-2015 National Ambulatory Medical Care Survey were analyzed, including 15,400,000 weighted primary acute HZV visits in adults. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02085-yDOI Listing

Preventing adverse cutaneous reactions from amplified hygiene practices during the COVID-19 pandemic: how dermatologists can help through anticipatory guidance.

Arch Dermatol Res 2020 May 9. Epub 2020 May 9.

Department of Dermatology, Rutgers Robert Wood Johnson Medical School, 1 World's Fair Dr, Ste 2400, Somerset, NJ, 08873, USA.

The COVID-19 pandemic has swept the globe with more than 2,000,000 confirmed cases of SARS-CoV-2 infection in 184 countries and territories. According to the Centers for Disease Control and Prevention (CDC), two crucial actions can reduce the risk of person-to-person viral transmission: frequent hand washing and surface decontamination with specific environmental protection agency (EPA)-registered disinfectants. As hygiene recommendations evolve during the COVID-19 pandemic and community members adopt changing practices, dermatologists are likely to see a rise in adverse cutaneous reactions from prolonged irritant exposures and widespread use of antimicrobials. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02086-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210798PMC

Thickness of carotid artery intima is an independent risk factor for psoriasis.

Arch Dermatol Res 2020 May 9. Epub 2020 May 9.

Department of Dermatology and Venereology, Ankara Numune Training and Research Hospital, Talatpaşa Street, 44, 06100, Altındağ, Ankara, Turkey.

Psoriasis (PsO) has been associated with lipoprotein abnormalities, visceral adiposity, atherosclerosis, and coronary artery disease (CAD) in several studies; however, data concerning the risk of psoriasis relevant to these parameters is not well established. We aimed to evaluate the relation between PsO and small dense low-density lipoprotein cholesterol (sd-LDL-C), serum lipid profile (SLP), blood pressures, anthropometric measurements, intima media thickness of the common carotid artery (CIMT), distribution of visceral adipose tissue (VAT; evaluated at 3 different measurement sites including VATa, VATb, VATc) along with subcutaneous (Sc-d1) and preperitoneal (Pre-d2) adipose tissue, and disease characteristics, so as to define relevant risk factors for PsO. In this cross-sectional and observational study, 62 patients with plaque-type PsO and 31 age- and sex-matched controls were enrolled. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02084-zDOI Listing

Distance learning in the era of COVID-19.

Arch Dermatol Res 2020 May 8. Epub 2020 May 8.

Washington University in St. Louis, St. Louis, MO, USA.

The novel coronavirus (SARS-CoV-2) pandemic has necessitated a dramatic shift in how our dermatology residents and fellows are educated. Distance or online learning has become the norm, and several national and international academic societies have combined resources to assure that continuing medical education occurs during this difficult time. The purpose of this communication is to review select online resources available to dermatology trainees and to encourage our colleagues to continue to advance our specialty through distance learning. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02088-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209972PMC

Protective effects of a comprehensive topical antioxidant against ozone-induced damage in a reconstructed human skin model.

Arch Dermatol Res 2020 May 8. Epub 2020 May 8.

skinbetter science, LLC, 3200 E Camelback Rd, Suite 395, Phoenix, AZ, USA.

Tropospheric ozone (O) is a source of oxidative stress. This study examined the ability of a topical antioxidant (WEL-DS) to inhibit O-mediated damage in a human epidermal skin model. Four groups of tissues (N = 24) were compared: Group 1 (control) were untreated and unexposed; Group 2 were untreated and exposed to O (0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02083-0DOI Listing

Sentinel lymph node biopsy for high-thickness cutaneous squamous cell carcinoma.

Arch Dermatol Res 2020 May 8. Epub 2020 May 8.

Department of Dermatology and Center for Dermatologic Surgery, Eberhard-Karls University of Tuebingen, Liebermeisterstraße 25, 72076, Tübingen, Germany.

Squamous cell carcinomas are among the most common skin tumors and show a risk of metastasis depending on various factors such as tumor thickness, localization, histological subtype and immune status of the patient. Sentinel lymph node biopsy (SLNB) SLNB represents a possibility for assessing the locoregional lymph node status. In this study, the role of the SLNB in lymph node status and survival was analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02082-1DOI Listing

Tumour-infiltrating lymphocyte and histological regression in primary melanoma.

Arch Dermatol Res 2020 May 7. Epub 2020 May 7.

Dermatology Department, Hospital Universitario y Politécnico la Fe, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02089-8DOI Listing
May 2020
2.270 Impact Factor

Correction to: Atopic dermatitis and autoimmunity: the occurrence of autoantibodies and their association with disease severity.

Arch Dermatol Res 2020 Jul;312(5):393

School of Life Sciences, University of Nottingham, Life Sciences Building, University Park, Nottingham, NG7 2RD, UK.

Two of the references included in this review concern antigens derived from the fungus Malassezia globosa that have also been found in human sweat. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02081-2DOI Listing

Therapeutic efficacy and safety of oral tranexamic acid 250 mg once a day versus 500 mg twice a day: a comparative study.

Arch Dermatol Res 2020 Apr 30. Epub 2020 Apr 30.

Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Kangra (Tanda), 176001, Himachal Pradesh, India.

Oral tranexamic acid (TXA) 250 mg twice daily has been used effectively for 4 weeks to 6 months to treat melasma. As relapses are frequent on discontinuation, a minimum effective dose of TXA that can be used safely for long time remains unknown. We compared the efficacy of oral TXA 250 mg once daily and 500 mg twice daily given for 16 weeks in 132 (m:f 23:109) adults with melasma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02078-xDOI Listing

Incorporation of dermoscopy improves inter-observer agreement among dermatopathologists in histologic assessment of melanocytic neoplasms.

Arch Dermatol Res 2020 Apr 27. Epub 2020 Apr 27.

Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Histopathologic assessment of melanocytic neoplasms is the current gold standard of diagnosis. However, there are well recognized limitations including inter-observer diagnostic discordance. This study aimed to determine if integrating dermoscopy with histopathology of melanocytic neoplasms impacts diagnosis and improves inter-observer agreement. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02079-wDOI Listing
April 2020
2.270 Impact Factor

Prevalence and cutaneous comorbidities of hidradenitis suppurativa in the German working population.

Arch Dermatol Res 2020 Apr 22. Epub 2020 Apr 22.

Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246, Hamburg, Germany.

The association of hidradenitis suppurativa with other skin diseases has not yet been investigated in larger studies based on dermatological exams. The objectives of this study are to determine the prevalence and cutaneous comorbidities of hidradenitis suppurativa in the German working population. Between 2014 and 2017, 20,112 people in 343 German companies were examined for the presence of clinical features of hidradenitis suppurativa within the framework of a cross-sectional epidemiological study based on whole-body examinations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02065-2DOI Listing

Tacrolimus (FK506) ointment combined with Nb-UVB could activate both hair follicle (HF) and dermal melanocyte precursors in vitiligo: the first histopathological and clinical study.

Arch Dermatol Res 2020 Apr 17. Epub 2020 Apr 17.

Skin Research Center, Shohada-E Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Shahrdari St, 1989934148, Tehran, Iran.

Topical Tacrolimus, especially when combined with Nb-UVB, has been proven clinically to be effective in the treatment of vitiligo. However, no histological study has evaluated the repigmentation mechanism of tacrolimus ointment in combination therapy with Nb-UVB. In this study, the histological findings in patients receiving Nb-UVB were compared with those receiving topical tacrolimus combined with Nb-UVB. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02068-zDOI Listing

Efficacy of health education on treatment of children with atopic dermatitis: a meta-analysis of randomized controlled trials.

Arch Dermatol Res 2020 Apr 15. Epub 2020 Apr 15.

Department of Dermatology, Children's Hospital, School of Medicine, University of Zhejiang, No. 3333 Binsheng Road, Hangzhou, Zhejiang, China.

Atopic dermatitis (AD) seriously affects the quality of life of children and their families. This meta-analysis aimed to comprehensively analyze health education on the treatment of children with AD and the quality of life of the patient's family. A comprehensive search of reference lists in PubMed, Embase, Cochrane Library, Wanfang, CNKI, and VIP databases from inception until April 2018 was performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02060-7DOI Listing

The "sister test" for selecting appropriate diagnostic interventions and treatments.

Authors:
Murad Alam

Arch Dermatol Res 2020 Apr 13. Epub 2020 Apr 13.

Department of Dermatology, Northwestern University, 676 N St Clair St, Suite 1600, Chicago, IL, 60611, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02077-yDOI Listing

Gender differences in psoriasis: a Swiss online psoriasis survey.

Arch Dermatol Res 2020 Apr 12. Epub 2020 Apr 12.

Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091, Zurich, Switzerland.

Physicians' and patients' perspectives can vary significantly. For a long time, physicians considered psoriasis a non-pruritic dermatosis until a survey found pruritus to be the most bothersome symptom among psoriasis patients. In our study, we wanted to get an insight into the factors that affect patients and evaluate whether gender differences exist. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02066-1DOI Listing

Dermal fillers should be renamed skin fillers.

Authors:
Murad Alam

Arch Dermatol Res 2020 Apr 11. Epub 2020 Apr 11.

Department of Dermatology, Northwestern University, 676 N St Clair St, Suite 1600, Chicago, IL, 60611, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02076-zDOI Listing

Trends in emergency department visits due to sunburn and factors associated with severe sunburns in the United States.

Arch Dermatol Res 2020 Apr 9. Epub 2020 Apr 9.

Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

Little is known regarding the burden of sunburns leading to emergency department (ED) visits in the United States (US). The objectives of this research were to characterize the burden of sunburn ED visits, investigate predictors of severe sunburns, and evaluate risk factors for increased cost of care in patients presenting to the ED for sunburn. In this nationally representative cross-sectional study of the National Emergency Department Sample (NEDS, 2013-2015), multivariable models were created to evaluate adjusted odds for sunburn ED visits, seasonal/regional variation in sunburn ED visits, adjusted odds for second and third degree sunburns, and risk factors for increased ED expenditure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02073-2DOI Listing

A cross-sectional survey of prevalence and correlates of sunscreen use among a rural Tri-State Appalachian population.

Arch Dermatol Res 2020 Apr 9. Epub 2020 Apr 9.

Department of Dermatology, School of Medicine, University of Mississippi Medical Center, 2500 North State Street-L216, Jackson, MS, 39216, USA.

Over five million people are diagnosed with skin cancers each year. With the sun's ultraviolet radiation exposure being the major risk factor for all skin cancers, sunscreen use is a vital preventative measure. However, in the US, sunscreen use remains inadequate. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02072-3DOI Listing

Quantitative measurement of skin surface oiliness and shine using differential polarized images.

Arch Dermatol Res 2020 Apr 8. Epub 2020 Apr 8.

Canfield Scientific Inc., Parsippany, NJ, USA.

Excess amounts of skin surface oil can lead to adverse psychological consequences. Grease-spot photometry-based techniques measure sebum production rate. However, besides being tedious, these measurements are influenced by contact area, applied pressure, and time of application. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02070-5DOI Listing

The utility of PROMIS domain measures in dermatologic care.

Arch Dermatol Res 2020 Apr 8. Epub 2020 Apr 8.

Department of Dermatology, University of Rochester Medical Center, 601 Elmwood Ave, Box 697, Rochester, NY, 14642, USA.

Patient-reported outcome (PRO) measures play an important role in clinical care. Currently, a broad-spectrum, validated PRO measure suitable for all dermatology patients, as part of clinical care, does not exist. Patient-reported Outcome Measures Information System (PROMIS) measures track specific domain outcomes across all diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02074-1DOI Listing

Age-specific physical and mental health status in Italian patients with hidradenitis suppurativa: a comparison with the general population.

Arch Dermatol Res 2020 Apr 8. Epub 2020 Apr 8.

Clinical Epidemiology Unit, IDI-IRCCS, Via dei Monti di Creta, 104, 00167, Rome, Italy.

Hidradenitis suppurativa (HS) has a considerable impact on quality of life. Despite comparisons of health status between HS patients and the general population have been done, there is a need to make more meaningful comparisons, such as age-specific ones. The objective of the study was to compare age-specific physical and mental health status in Italian patients with HS to that of a representative sample of the Italian general population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02063-4DOI Listing

The polymorphisms of IL-6/STAT3 signaling pathway may contribute to cutaneous T-cell lymphomas susceptibility.

Arch Dermatol Res 2020 Apr 8. Epub 2020 Apr 8.

Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Mariana Smoluchowskiego Str 17, 80-214, Gdańsk, Poland.

IL-6/STAT3 signaling pathway has been suggested to play a role in CTCL pathogenesis. Polymorphisms in STAT3 signaling pathway-related genes might be a risk factor for CTCL. However, the exact role of inherited gene polymorphisms of IL-6 and STAT3 in the pathogenesis of CTCL is still not fully understood. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02062-5DOI Listing

The association of chronic spontaneous urticaria (CSU) with anxiety and depression: a nationwide cohort study.

Arch Dermatol Res 2020 Apr 8. Epub 2020 Apr 8.

Clalit Health Services, Tel Aviv, Israel.

Chronic spontaneous urticaria (CSU) is a dermatological disease associated with significant impairment of overall quality of life as well as psychological distress. Previous studies have demonstrated significant comorbidity between CSU and a wide range of mental illnesses. In this study we aimed to focus on the association between CSU and anxiety and depression, using an optimized matched controlled design. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02064-3DOI Listing

High level of TILs is an independent predictor of negative sentinel lymph node in women but not in men.

Arch Dermatol Res 2020 Apr 8. Epub 2020 Apr 8.

Department of Epidemiology, Lazio Regional Health Service, Rome, Italy.

Factors that are most associated with positive lymph node status in melanoma are Breslow thickness and ulceration. However, there are other factors that have been little explored and could help in the identification of "at risk patients" harbouring occult metastasis. The objective of this study was to determine whether intensity of tumour-infiltrating lymphocytes (TILs) in a cohort study (N = 4133) is an independent predictor of sentinel lymph node (SLN) status in patients with primary cutaneous melanoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02067-0DOI Listing

Daylight photodynamic therapy for the management of actinic cheilitis.

Arch Dermatol Res 2020 Apr 7. Epub 2020 Apr 7.

First Dermatology Department, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Early identification and adequate treatment of actinic cheilitis (AC), which affects the lower lip vermillion and is considered a precursor of squamous cell carcinoma, is mandatory. Photodynamic therapy (PDT) has been successfully used in AC. PDT with the use of daylight (DLPDT) is equally effective and more convenient than the conventional PDT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02069-yDOI Listing

Pain-less injection: principles and pearls.

Arch Dermatol Res 2020 Apr 7. Epub 2020 Apr 7.

Department of Dermatology, Brooklyn Veterans Hospital, 800 Poly Place, Brooklyn, NY, 11209, USA.

There has been an exponential growth in the number of dermatologic procedures performed over the past two decades. This surge in procedural volumes is accompanied by increasing utilization of local anesthetics. A proper technique in administering local anesthesia is necessary to minimize pain and promote comfort, as it is often regarded as the most painful part of cutaneous procedures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02075-0DOI Listing

Trichloroacetic acid model to accurately capture the efficacy of treatments for postinflammatory hyperpigmentation.

Arch Dermatol Res 2020 Apr 6. Epub 2020 Apr 6.

Department of Dermatology, Henry Ford Hospital, 3031 West Grand Blvd, Detroit, MI, 48202, USA.

Postinflammatory hyperpigmentation (PIH) occurs following cutaneous injury and is common following resolution of acne especially in patients with skin of color. The objective of this study was to further validate a trichloroacetic acid (TCA)-induced PIH model and compare it to acne-induced PIH using topical bakuchiol, a botanical extract that has been shown to have antimicrobial, anti-inflammatory, antioxidant, and antiacne properties. A prospective, non-randomized clinical trial was conducted on subjects with skin phototypes IV-VI with a history of acne-induced PIH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02071-4DOI Listing

Small molecules under development for psoriasis: on the road to the individualized therapies.

Arch Dermatol Res 2020 Mar 14. Epub 2020 Mar 14.

Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Edif B-1, Ciudad Universitaria, Francisco J. Mújica, s/n, 58030, Morelia, Michoacán, Mexico.

Psoriasis is an incurable cutaneous illness characterized by the presence of well-delimited reddish plaques and silvery-white dry scales. So far, there is a limited understanding of its pathogenesis, though recent discoveries on the immunological, genetic and molecular aspects of this disease have significantly contributed to the identification of new targets and the development of novel drugs. Despite these advances, many patients are still dissatisfied, so to improve patient satisfaction, reliability, and clinical outcomes, the individualization of the treatments for this disease becomes a necessity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02056-3DOI Listing

Reappraising basosquamous carcinoma: a summary of histologic features, diagnosis, and treatment.

Arch Dermatol Res 2020 Mar 12. Epub 2020 Mar 12.

Brooklyn Campus of the VA NY Harbor Healthcare System, 800 Poly Place, Brooklyn, NY, 11209, USA.

Basosquamous carcinoma (BSC) is a malignant and aggressive neoplasm with unclear molecular etiology. It is often misdiagnosed as basal cell carcinoma (BCC) or squamous cell carcinoma (SCC) on biopsy as there are unclear histologic criteria for this neoplasm. It has been interchangeably referred to as metatypical BCC and collision tumor, although these entities are different. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02058-1DOI Listing

PIWIL-2 and piRNAs are regularly expressed in epithelia of the skin and their expression is related to differentiation.

Arch Dermatol Res 2020 Mar 12. Epub 2020 Mar 12.

Department of Dermatology, Medical University of Vienna, Vienna, Austria.

PIWI proteins play multiple roles in germline stem cell maintenance and self-renewal. PIWI-interacting RNAs (piRNAs) associate with PIWI proteins, form effector complexes and maintain genome integrity and function in the regulation of gene expression by epigenetic modifications. Both are involved in cancer development. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02052-7DOI Listing

A novel oxidative stress marker of atopic dermatitis in infants: thiol-disulfide balance.

Arch Dermatol Res 2020 Mar 11. Epub 2020 Mar 11.

Department of Clinical Biochemistry, Yildirim Beyazit University, Faculty of Medicine, Ankara, 06010, Turkey.

Atopic dermatitis (AD) is a chronic disease of infancy and its pathogenesis remains unclear. There are recent studies suggesting that oxidative stress could play a role in the pathophysiology of atopic dermatitis. The aim of this study was to evaluate thiol (SH)-disulfide (SS) hemostasis as a new marker of oxidative stress (OS) in infants with atopic dermatitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02054-5DOI Listing
March 2020
2.270 Impact Factor

MiR-4458/human antigen R (HuR) modulates PBX3 mRNA stability in melanoma tumorigenesis.

Arch Dermatol Res 2020 Mar 9. Epub 2020 Mar 9.

Department of Dermatology and Dermatologic Surgery, Shanghai Ninth People's Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Center for Specialty Strategy Research of Shanghai JiaoTong University China Hospital Development Institute, No. 639 Zhizaoju Road, Shanghai, 200011, China.

Melanoma, a malignancy of the melanocyte, is characterized as the most fatal skin cancer with an increasing incidence. Of note, in spite of great attempts made for better treatment, the therapeutic outcome is barely satisfactory. Abnormal expression of microRNAs (miRNAs) acting as oncogenes or tumor suppressor genes, is frequently implicated in multiple human cancers, including melanoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02051-8DOI Listing

Psoriasin and rs4819554 of IL-17RA gene polymorphism in psoriasis.

Arch Dermatol Res 2020 Mar 9. Epub 2020 Mar 9.

Dr DY Patil University, Pune, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02055-4DOI Listing

Predictive in silico binding algorithms reveal HLA specificities and autoallergen peptides associated with atopic dermatitis.

Arch Dermatol Res 2020 Mar 9. Epub 2020 Mar 9.

Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Atopic dermatitis (AD) is a skin disease that results from a combination of skin barrier dysfunction and immune dysregulation. The immune dysregulation is often associated with IgE sensitivity. There is also evidence that autoallergens Hom s 1, 2, 3, and 4 play a role in AD; it is possible that patients with specific HLA subtypes are predisposed to autoreactivity due to increased presentation of autoallergen peptides. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02059-0DOI Listing

Psoriasis is not a risk factor for dementia: a 12-year nationwide population-based cohort study.

Arch Dermatol Res 2020 Mar 9. Epub 2020 Mar 9.

Department of Dermatology, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, 11217, Taiwan.

Studies investigating the risk for dementia in psoriatic patients remain inconclusive. There are a limited number of population-based studies on the association between psoriasis and dementia. This study aims to investigate the risk for dementia in psoriatic patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02057-2DOI Listing

Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.

Arch Dermatol Res 2020 Feb 27. Epub 2020 Feb 27.

Department of Dermatology, Huashan Hospital, Fudan University, No. 12th Middle Wulumuqi Road, Shanghai, 200040, China.

Postinflammatory hyperpigmentation (PIH) is a common disfiguring complication following inflammatory dermatoses and cosmetic procedures in dark-skinned individuals. Anti-inflammatory and repairing agents targeting primary inflammation and injury are becoming promising choices for preventing PIH. The aim of this active-controlled, assessor-blinded, intra-individual monocentric study was to evaluate the preventive effect of a wound-dressing biomaterial, mussel adhesive protein (MAP) in the suction blister-induced PIH model. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02049-2DOI Listing
February 2020
2.270 Impact Factor

"Psychodermatology" knowledge, attitudes, and practice among health care professionals.

Arch Dermatol Res 2020 Feb 25. Epub 2020 Feb 25.

Department of Preventive Medicine, School of Medicine/John D. Bower School of Population Health, University of Mississippi Medical Center, Jackson, MS, USA.

Psychiatric disorders are prevalent in dermatology patients. Psychodermatology is the body of knowledge at the intersection of psychiatry and dermatology practice. The purpose of this literature review was to assess the knowledge, attitudes, and practices of health care professionals regarding psychodermatology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02050-9DOI Listing
February 2020

Skin cancer screening is the standard of care and should be made more accessible to patients.

Arch Dermatol Res 2020 Apr 25;312(3):229-230. Epub 2020 Feb 25.

American Society for Mohs Surgery, Long Beach, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02047-4DOI Listing

Insights into recurrent body-focused repetitive behaviors: evidenced by New York Times commenters.

Arch Dermatol Res 2020 Feb 20. Epub 2020 Feb 20.

Department of Dermatology, Weill Cornell Medical College, 1305 York Ave, 9th Floor, New York, NY, 10021, USA.

In September 2019, the New York Times (NYT) published the article "Fighting the Shame of Skin Picking," which discussed the cosmetic, social and emotional impacts of body-focused repetitive behaviors (BFRBs). BFRBs, including excoriation disorder, trichotillomania, onychotillomania, and onychophagia, are recurring actions that damage one's physical appearance. The aim of this study is to characterize the demographic information provided and themes raised in the 166 comments posted in response to the article. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02045-6DOI Listing
February 2020

Association of prurigo nodularis and lichen simplex chronicus with hospitalization for mental health disorders in US adults.

Arch Dermatol Res 2020 Feb 20. Epub 2020 Feb 20.

Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Suite 2B-425, 2150 Pennsylvania Avenue NW, Washington, DC, 20037, USA.

Prurigo nodularis (PN) and lichen simplex chronicus (LSC) are debilitating chronic pruritic diseases that can lead to and be exacerbated by psychosocial distress. However, little is known about the mental health (MH) comorbidities of PN/LSC. We sought to evaluate the likelihood and cost-burden of MH comorbidities and emergencies associated with PN/LSC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02046-5DOI Listing
February 2020

Retrospective analysis of adverse events with topical onychomycosis medications reported to the United States Food and Drug Administration.

Arch Dermatol Res 2020 Feb 19. Epub 2020 Feb 19.

Department of Dermatology, Weill Cornell Medicine, 1305 York Avenue, New York, NY, 10021, USA.

Topical onychomycosis therapy is commonly prescribed due to its tolerability and low incidence of side effects. There are limited data on adverse events associated with the newer topical onychomycosis drugs. The objectives of this study is to classify the most common adverse reactions associated with ciclopirox 8% solution, efinaconazole 10% solution, and tavaborole 5% solution. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02044-7DOI Listing
February 2020

Facial rejuvenation using photodynamic therapy with a novel preparation of ALA and hyaluronic acid in young adults.

Arch Dermatol Res 2020 Feb 14. Epub 2020 Feb 14.

Department of Dermatology, State University of New York, Downstate Health Sciences University, 450 Clarkson Ave, Box 46, Brooklyn, NY, USA.

Photodynamic therapy (PDT) is a well-established, non-invasive treatment modality that has shown desirable effects such as improvement of fine lines, dyspigmentation, and other signs of photodamage. Many patients seek to decrease, or reverse, effects of sun damage on the skin. Hyaluronic acid (HA), a naturally occurring glycosaminoglycan found in the body, has enormous potential to bind water which allows the skin to retain moisture and maintain elasticity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02038-5DOI Listing
February 2020
2.270 Impact Factor

Three-dimensional modeling and comparison of nasal flap designs.

Arch Dermatol Res 2020 Feb 14. Epub 2020 Feb 14.

Department of Dermatology, University of Minnesota, 516 Delaware St. SE, Mail Code 98, Philips-Wangensteen Building, Suite 4-420, Minneapolis, MN, 55455, USA.

Few studies exist that compare local flap repair designs either mathematically or clinically. Previous mathematical studies use a two-dimensional modeling approach, which is not suited to complex structures like the nose. To quantitatively analyze and compare flap designs for nasal repair using three-dimensional, photographic models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02039-4DOI Listing
February 2020

The relationship between the number of available therapeutic options and government payer (medicare part D) spending on topical drug products.

Arch Dermatol Res 2020 Feb 13. Epub 2020 Feb 13.

Department of Dermatology, Northwestern University Feinberg School of Medicine, 2701 Patrio Blvd, Glenview, Chicago, IL, USA.

The cost of prescription drugs has increased at rates far exceeding general inflation in recent history, with topical drugs increasing at a disproportionate rate compared to other routes of administration. We assessed the relationship between net changes in the number of therapeutic options, defined as any approved drug or therapeutic equivalent on the market, and prescription topical drug spending. Drugs were divided based on the category of use through pairing of Medicare Part D Prescriber Public Use and Food and Drug Administration (FDA) approved drug products databases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02042-9DOI Listing
February 2020

Skin cancer-related knowledge, attitudes, beliefs, and practices among the population in Gulf Cooperation Council countries: a systematic search and literature review.

Arch Dermatol Res 2020 Feb 13. Epub 2020 Feb 13.

Department of Dermatology, School of Medicine, University of Mississippi Medical Center, 2500 North State Street-L216, Jackson, MS, 39216, USA.

Skin cancers are the most common malignancies diagnosed worldwide. In Gulf Cooperation Council (GCC) countries, skin cancer remains a significant health burden. Multiple studies have attempted to elucidate patient knowledge and attitudes regarding skin cancer risks and behavioral interventions to reduce risks. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02041-wDOI Listing
February 2020