Department of Cardiology, Princess Grace Hospital, Pasteur Avenue, Monaco.
Background: Activation mapping can be challenging and time-consuming in patients with multiple atrial tachycardias (ATs).
Aims: To compare multielectrode mapping using a dedicated mapping catheter - PentaRay (Biosense Webster Inc.) - and the conventional technique for mapping ATs in the context of atrial fibrillation (AF) ablation. Read More
Department of Cardiology, University Hospital "Dr Dragisa Misovic-Dedinje", Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Background: Detailed analysis of layer-specific mechanical changes in patients with type 2 diabetes mellitus (DM) might improve insight into left ventricular (LV) remodelling and diabetic cardiomyopathy.
Aim: We sought to investigate layer-specific LV deformation in patients with DM, with and without hypertension.
Methods: This cross-sectional study included 146 subjects (44 controls; 48 patients with DM; 54 patients with DM and hypertension) who underwent complete examination by two-dimensional echocardiography (2DE), including multilayer strain analysis. Read More
Physiopathologie et épidémiologie cérébro-cardiovasculaires (EA7460), faculté des sciences de santé (médecine pharmacie), Dijon, université de Bourgogne, 7, boulevard Jeanne-d'Arc, BP 87900, 21079 Dijon cedex, France; Service de cardiologie, CHU François-Mitterrand, Dijon, France.
Air pollution is composed of particulate matter (PM) and gaseous pollutants, such as nitrogen dioxide and ozone. PM is classified according to size into coarse particles (PM10), fine particles (PM2.5) and ultrafine particles. Read More
Epidemiological studies using coronary artery calcification measurement have linked calcification strongly with coronary events and mortality. Formerly considered as a passive age-related phenomenon, coronary artery calcification is now recognized as an active and regulated process. In fact, there is a local influence linked to the inflammation generated by the presence of oxidized lipids and, equally, a general influence from mineral metabolism factors, such as inorganic phosphate, calcium, pyrophosphate or fibroblast growth factor 23, which are regulators of cell differentiation and of phosphate and calcium deposition on the vascular layers. Read More
Arch Cardiovasc Dis 2017 Jun 29. Epub 2017 Jun 29.
Department of cardiology, Charité-university-medicine Berlin, Berlin, Germany; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Standort Berlin/Charité, Berlin, Germany; Department of cardiology, Deutsches Herzzentrum Berlin (DHZB), Berlin, Germany.
The number of studies demonstrating the importance of right ventricular remodelling in a wide range of cardiovascular diseases has increased in the past two decades. Speckle-tracking imaging provides new variables that give comprehensive information about right ventricular function and mechanics. In this review, we summarize current knowledge of right ventricular mechanics in heart failure with reduced ejection fraction and preserved ejection fraction. Read More
Background: As the number of transcatheter aortic valve implantation (TAVI) procedures is constantly increasing, it is important to consider common complications, such as pacemaker (PM) implantation, and their specific risk factors.
Aims: Echocardiographic, computed tomography and electrocardiographic data were analysed to determine the predicting factors, if any, associated with PM implantation.
Methods: This retrospective study included patients referred to Nancy University Hospital for a TAVI procedure from January 2013 to December 2015. Read More
Background: The FAST-MI programme, consisting of 1-month surveys of patients admitted to hospital for acute myocardial infarction (AMI) in France, has run since 2005.
Aim: To gather data on the characteristics, management and outcomes of patients hospitalized for AMI at the end of 2015 in France and to provide comparisons with the previous surveys.
Methods: Consecutive adults with ST-segment elevation myocardial infarction (STEMI) or non-ST-segment-elevation myocardial infarction (NSTEMI) with symptom onset≤48hours were included over a 1-month period, with a possible extension of recruitment for 1 additional month. Read More
Oral health is of particular importance in patients with heart valve diseases because of the risk of infective endocarditis. Recommendations for antibiotic prophylaxis before dental procedures have been restricted, but the modalities of oral evaluation and dental care are not detailed in guidelines. Therefore, a multidisciplinary working group reviewed the literature to propose detailed approaches for the evaluation and management of buccodental status in patients with valvular disease. Read More
Background: The use of bilateral internal thoracic artery (BITA) grafting has been proposed for dialysis patients with multivessel coronary artery disease, primarily because of hypothetical long-term survival benefits.
Aims: To investigate the outcome of BITA grafting in dialysis patients.
Methods: This was a retrospective analysis of the use of BITA grafting in 105 consecutive patients with end-stage renal failure on chronic dialysis in three European centres with extensive experience in BITA. Read More
Department of cardiology, Mustapha Hospital university, 1, place du 1(er)-Mai, 16001 Algiers, Algeria; Cardiology Oncology Research Collaborative Group (CORCG), University of Medicine of Algiers Benyoucef Benkhedda, Algiers, Algeria.
Background: High P2Y12 platelet reactivity (PR) level after primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) affects prognosis and may induce the no-reflow phenomenon.
Aim: To investigate the role of PR in the genesis of microvascular obstruction.
Methods: Patients with STEMI undergoing PPCI within 12hours of symptoms onset were included prospectively. Read More
Background: Three-dimensional (3D) transthoracic echocardiography (TTE) is superior to two-dimensional Simpson's method for assessment of left ventricular (LV) volumes and LV ejection fraction (LVEF). Nevertheless, 3D TTE is not incorporated into everyday practice, as current LV chamber quantification software products are time-consuming.
Aims: To evaluate the feasibility, accuracy and reproducibility of new fully automated fast 3D TTE software (HeartModel(A. Read More
Background: Ebstein's anomaly is a complex malformation. Justification of a procedure in mildly symptomatic adults is debatable: repair techniques are demanding and valve replacement is associated with poorer outcome.
Objectives: We report our initial experience with the cone procedure versus medical follow-up. Read More
Arch Cardiovasc Dis 2017 Aug - Sep;110(8-9):456-465. Epub 2017 May 26.
UMR 7211, Inflammation-Immunopathology-Biotherapy Department, Département de Médecine Interne et d'Immunologie Clinique, Sorbonne Universités, UPMC Université Paris, CHU Pitié-Salpétrière, 75005 Paris, France.
Background: Cardiac sarcoidosis (CS) is a severe localization, observed mostly in cardiology departments. Despite appropriate cardiological treatment, CS is a potentially life-threatening condition, and accounts for 13-85% of sarcoidosis-related deaths.
Aims: This retrospective study aimed to give an overview of CS in a non-cardiac unit, to analyse the effect of first-line immunosuppressive treatment on outcome and survival and to evaluate factors associated with relapses. Read More
Nowadays, guidelines are derived from the findings of randomized controlled therapeutic trials. However, an overall significant P value does not exclude that some patients may be harmed by or will not respond to the therapeutic agent being studied. Trials in patients with a low risk of events and/or a limited chance of providing significant differences in therapeutic effects require a large patient population to demonstrate a beneficial effect. Read More
Arch Cardiovasc Dis 2017 May 23. Epub 2017 May 23.
Centre de reference malformations cardiaques congenitales complexe - M3C, hôpital Necker-Enfants-Malades, hôpital européen Georges-Pompidou, AP-HP, 149, rue de Sèvres, 75015 Paris cedex, France; Université Paris-Descartes, Paris, France.
Background: Given the potential complications of atrial fibrillation (AF) recurrence after ablation, better predictors of the effectiveness of the procedure are necessary to guide patient selection.
Aim: This prospective study was conducted to evaluate the clinical relevance of global left atrial longitudinal strain (GLAS) and AF recurrence after catheter ablation.
Methods: In 115 consecutive patients with AF (persistent, n=62; paroxysmal, n=53), transthoracic echocardiography was performed before catheter ablation to assess baseline left atrial mechanical function using speckle tracking echocardiography (STE). Read More
Arch Cardiovasc Dis 2017 Aug - Sep;110(8-9):475-481. Epub 2017 May 11.
INSERM, CIC-1421 and UMR ICAN 1166, France; Department of Pharmacology and CIC-1421, Pitié-Salpêtrière Hospital, AP-HP, France; Faculty of Medicine, Sorbonne University, UPMC University of Paris 06, France; Institute of Cardiometabolism and Nutrition (ICAN), Paris, France. Electronic address:
Background: The gold standard method for assessing the QTcF (QT corrected for heart rate by Fridericia's cube root formula) interval is the "QTcF semiautomated triplicate averaging method" (TAM), which consists of measuring three QTcF values semiautomatically, for each 10-second sequence of a triplicate electrocardiogram set, and averaging them to get a global and unique QTcF value. Thus, TAM is time consuming. We have developed a new method, namely the "QTcF semiautomated triplicate concatenation method" (TCM), which consists of concatenating the three 10-second sequences of the triplicate electrocardiogram set as if they were a single 30-second electrocardiogram, and measuring QTcF only once for the triplicate electrocardiogram set. Read More
Background: Some patients who are at high surgical risk because of multiple co-morbidities undergo balloon aortic valvuloplasty (BAV) as a bridge therapy towards transcatheter aortic-valve implantation (TAVI).
Aim: The aim of this study was to compare the clinical course of patients with or without previous BAV who underwent TAVI and were included in the FRANCE 2 registry.
Methods: From January 2010 to December 2011, 3953 patients underwent TAVI. Read More
Background: Transcarotid access is an alternative route for transcutaneous aortic valve implantation (TAVI) in patients with impossible transfemoral access.
Aims: We evaluated the safety, effectiveness and early and late clinical outcomes of CoreValve(®) implantation via the common carotid artery.
Methods: Eighteen patients (10 men, 8 women; mean age 84±5 years) at high surgical risk (mean EuroSCORE II 16±13%) with significant peripheral artery disease underwent TAVI via common carotid artery access under general anaesthesia. Read More
People living with human immunodeficiency virus (HIV) infection and receiving antiretroviral therapy now have the same life expectancy as the general population. However, they have a higher risk of atherosclerotic cardiovascular events because of a complex and polyfactorial vasculopathy, combining the effects of antiretroviral therapy, the HIV virus itself, immune activation, chronic inflammation and metabolic disturbances. Whether people living with HIV infection experience increased vascular aging compared with the general population remains controversial. Read More
Background: The causes of procedural deaths after transcatheter aortic valve implantation (TAVI) have been scarcely detailed.
Aims: To assess these causes and their temporal trends since the beginning of the TAVI era.
Methods: From October 2006 to April 2014, 601 consecutive high-risk/inoperable patients with severe aortic stenosis underwent TAVI using the Edwards SAPIEN or SAPIEN XT or the Medtronic CoreValve. Read More
Pulmonary hypertension due to left heart disease, also known as group 2 pulmonary hypertension according to the European Society of Cardiology/European Respiratory Society classification, is the most common cause of pulmonary hypertension. In patients with left heart disease, the development of pulmonary hypertension favours right heart dysfunction, which has a major impact on disease severity and outcome. Over the past few years, this condition has been considered more frequently. Read More
Managerial Epidemiology Research Center, Department of Public Health, School of Nursing and Midwifery, Maragheh University of Medical Sciences, Maragheh, Iran; Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:
Service de cardiologie, GCS-groupement des hôpitaux de l'institut catholique de Lille, faculté libre de médecine, université catholique de Lille, 59000 Lille, France; Inserm U 1088, université de Picardie, 80054 Amiens, France. Electronic address:
Background And Aims: We hypothesized that large exercise-induced increases in aortic mean pressure gradient can predict haemodynamic progression during follow-up in asymptomatic patients with aortic stenosis.
Methods: We retrospectively identified patients with asymptomatic moderate or severe aortic stenosis (aortic valve area<1.5cm(2) or<1cm(2)) and normal ejection fraction, who underwent an exercise stress echocardiography at baseline with a normal exercise test and a resting echocardiography during follow-up. Read More
Supraventricular arrhythmias are an important and increasing cause of morbidity in adults with congenital heart disease, requiring specific management strategies. Pharmacological treatment has limited efficacy, and is often associated with some side-effects. Major improvements in catheter ablation techniques have opened new opportunities to better understand underlying mechanisms of supraventricular arrhythmias, offer better therapy, and eventually improve symptoms and quality of life in these patients. Read More
Background: Monomorphic ventricular tachycardia (MVT) is common in adults with repaired tetralogy of Fallot (TOF), and is associated with sudden cardiac death. Management of MVT is not defined, and results of catheter ablation (CA) are limited.
Aims: To evaluate long-term outcomes of MVT CA in repaired TOF. Read More
Background: Adolescents and young adults with congenital heart disease (CHD) have complex health needs and require lifelong follow-up. Interventions to facilitate the paediatric-to-adult healthcare transition are recommended, but outcomes remain largely under-investigated.
Aims: To identify the educational needs and the impact of a transition intervention on knowledge and self-management skills in adolescents and young adults with CHD. Read More
Arch Cardiovasc Dis 2017 May 14;110(5):283-291. Epub 2017 Mar 14.
Adult Congenital Heart Disease Unit, Cardiology Department, Hôpital Européen Georges Pompidou, France; Paediatric Cardiology, Necker Hospital, AP-HP, France; Paris Descartes University, Paris, France; Paris Cardiovascular Research Centre (PARCC), INSERM U970, Paris, France. Electronic address:
Arch Cardiovasc Dis 2017 May 9;110(5):303-316. Epub 2017 Mar 9.
Adult congenital heart diseases unit, department of cardiology, centre de référence M3C, hôpital européen Georges-Pompidou, Assistance publique-Hôpitaux de Paris, Paris, France; Paris cardiovascular research centre (PARCC), Inserm U970, Paris Descartes University, Paris, France; Centre de référence malformations cardiaques congénitales complexes M3C, hôpital universitaire Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, université Paris Descartes, Sorbonne Paris Cité, Paris, France.
The drug-coated balloon (DCB) has emerged as an additional tool in the arsenal of interventional cardiology devices; it delivers antiproliferative drugs to local arterial tissue by single prolonged coated balloon angioplasty inflation, and prevents restenosis, leaving no implant behind. This strategy theoretically decreases the risk of late inflammatory response to device components, without preventing positive remodelling. DCBs, when used carefully and with a good technique, may have a role in the treatment of lesion subsets, such as in-stent restenosis, small vessel disease or side branch bifurcations, in which the implantation of a drug-eluting stent is not desirable or is technically challenging. Read More
With the advances in congenital cardiac surgery and postoperative care, an increasing number of children with complex congenital heart disease now reach adulthood. There are already more adults than children living with a congenital heart defect, including patients with complex congenital heart defects. Among these adults with congenital heart disease, a significant number will develop ventricular dysfunction over time. Read More
Background: Cardiovascular disease is the primary cause of death in women. Prevention, screening and diagnosis are generally implemented at later stages and less frequently than in men, and provision of treatment is not optimal in women.
Aims: To assess the relevance of targeted screening for myocardial ischaemia in women with multiple risk factors, and to identify which specific factors target women more effectively. Read More
The left atrial septal pouch (LASP) is formed by incomplete fusion of the septum primum and septum secundum, leaving a cavity open towards the left atrium, but without interatrial shunting. There is no recommendation concerning strategy in the presence of a LASP, especially in the setting of stroke. The aim of this review was to determine whether the LASP could be incriminated as the aetiology of a stroke. Read More
Malignant ventricular arrhythmias and sudden cardiac death may late happen in repaired tetralogy of Fallot, although probably less frequently than previously thought, especially with the advent of new surgical techniques/management. Ventricular tachycardias are caused by reentry around the surgical scars/patches and valves. Many predictive factors have been proposed, which suffer from poor accuracy. Read More
Arch Cardiovasc Dis 2017 Mar 14;110(3):196-201. Epub 2017 Feb 14.
Department of Cardiology, AP-HP, Bichat Hospital, 75018 Paris, France; Inserm U1148, Bichat Hospital, 75018 Paris, France; University Paris Diderot, Sorbonne Paris Cité, UMR-S 1148, 75870 Paris, France. Electronic address:
Recurrence of mitral regurgitation after mitral valve repair is correlated with unfavourable left ventricular remodelling and poor outcome. This pictorial review describes the echocardiographic features of three types of acute mitral valve repair dysfunction, and the additional value of three-dimensional echocardiography. Read More