Search our Database of Scientific Publications and Authors

I’m looking for a

    1069 results match your criteria Archives of Cardiovascular Diseases[Journal]

    1 OF 22

    Prospective assessment of the frequency of low gradient severe aortic stenosis with preserved left ventricular ejection fraction: Critical impact of aortic flow misalignment and pressure recovery phenomenon.
    Arch Cardiovasc Dis 2018 Feb 10. Epub 2018 Feb 10.
    Service de cardiologie, faculté libre de médecine, université catholique de Lille, GCS-groupement des hôpitaux de l'Institut catholique de Lille, 59160 Lomme, France; Inserm U1088, université de Picardie, 80054 Amiens, France. Electronic address:
    Background: The frequency of paradoxical low-gradient severe aortic stenosis (AS) varies widely across studies. The impact of misalignment of aortic flow and pressure recovery phenomenon on the frequency of low-gradient severe AS with preserved left ventricular ejection fraction (LVEF) has not been evaluated in prospective studies.

    Aims: To investigate prospectively the impact of aortic flow misalignment by Doppler and lack of pressure recovery phenomenon correction on the frequency of low-gradient (LG) severe aortic stenosis (AS) with preserved LVEF. Read More

    Multilayer global longitudinal strain in patients with cancer: A comparison of two vendors.
    Arch Cardiovasc Dis 2018 Feb 5. Epub 2018 Feb 5.
    Service de cardiologie, hôpital Saint-Antoine, AP-HP, université Pierre-et-Marie-Curie, Paris-Sorbonne, Paris VI, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France. Electronic address:
    Background: Global longitudinal strain (GLS) has several sources of variation. Strain multilayer tracking is a new tool that has not yet been validated in clinical practice.

    Aim: The purpose of this study was to investigate intervendor variability when measuring multilayer strain in patients receiving chemotherapy for cancer. Read More


    Initiation and continuation of oral anticoagulant prescriptions for stroke prevention in non-valvular atrial fibrillation: A cohort study in primary care in France.
    Arch Cardiovasc Dis 2018 Feb 2. Epub 2018 Feb 2.
    Centre hospitalier universitaire Trousseau et université François-Rabelais, 37000 Tours, France.
    Background: Oral anticoagulants are prescribed in non-valvular atrial fibrillation for stroke prevention; however, little is known about the current management of anticoagulation in France, particularly given the availability of non-vitamin K antagonist oral anticoagulants in recent years.

    Aims: To describe the characteristics of patients prescribed oral anticoagulants, and assess treatment persistence in French primary care.

    Methods: We conducted a cohort study of patients with non-valvular atrial fibrillation, who were newly prescribed oral anticoagulants between 1 January 2014 and 31 January 2016, using French primary care data (IMS Longitudinal Patient Database). Read More

    Response to the letter: The high burden of coronary artery disease in heart failure with preserved ejection fraction.
    Arch Cardiovasc Dis 2018 Jan 4. Epub 2018 Jan 4.
    Unit of Heart Failure and Valvular Heart Diseases, Department of Cardiology, hôpital Nord, Aix-Marseille University, AP-HM, 13015 Marseille, France; Centre de recherche cardiovasculaire et nutrition (C2VN), UMR MD2, Inserm 1263, Inra, Aix-Marseille université, 13005 Marseille, France.

    Adverse impact of diabetes mellitus on left ventricular remodelling in patients with chronic primary mitral regurgitation.
    Arch Cardiovasc Dis 2018 Jan 3. Epub 2018 Jan 3.
    Cardiac Ultrasound Laboratory and Cardiovascular Research Center, Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston MA 02114, USA; Cardiac Ultrasound Laboratory, Perelman Center for Advanced Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:
    Background: Diabetes mellitus (DM) has an impact on left ventricular (LV) geometry and function, and is associated with worsening of pressure-overload LV remodelling; however, its impact on volume-overload LV remodelling is unknown.

    Aim: The objective of the study was to examine the association between DM and LV remodelling in patients with chronic mitral regurgitation (MR) caused by mitral valve prolapse.

    Methods: During a median follow-up of 3. Read More

    Long-term clinical outcomes in patients with cardiogenic shock according to left ventricular function: The French registry of Acute ST-elevation and non-ST-elevation Myocardial Infarction (FAST-MI) programme.
    Arch Cardiovasc Dis 2017 Dec 28. Epub 2017 Dec 28.
    Department of Cardiology, HEGP, AP-HP, 75015 Paris, France; Université Paris-Descartes, 75006 Paris, France.
    Background: Cardiogenic shock (CS) complicating acute myocardial infarction (AMI) remains a major concern. Failure of the left ventricular (LV) pump is the primary insult in most forms of CS, but other parts of the circulatory system and diastolic function contribute to shock. However, little is known of the clinical presentation, management and outcomes according to LV function in these patients. Read More

    Percutaneous coronary artery interventions in the paediatric population: Periprocedural and late outcome.
    Arch Cardiovasc Dis 2017 Dec 26. Epub 2017 Dec 26.
    Paediatric Cardiology, Centre de référence malformations cardiaques congénitales complexes, M3C, Necker Hospital for Sick Children, Assistance Publique des hôpitaux de Paris, 75105 Paris, France; Université Paris V Descartes, 75006 Paris, France.
    Background: Percutaneous coronary interventions (PCIs) are generally performed in adults with ischaemic heart disease, but reports of experience in the paediatric population are relatively limited.

    Aims: To report indications, interventional techniques and procedural outcomes for PCI in children treated in two French institutions.

    Methods: Medical records of all children in whom a PCI was attempted in two French tertiary institutions between 1998 and 2015 were systematically reviewed. Read More

    Assessment of potential heart donors: A statement from the French heart transplant community.
    Arch Cardiovasc Dis 2018 Feb 23;111(2):126-139. Epub 2017 Dec 23.
    Service de cardiologie, hôpital cardiologique, centre hospitalier régional et universitaire de Lille, 59000 Lille, France.
    Assessment of potential donors is an essential part of heart transplantation. Despite the shortage of donor hearts, donor heart procurement from brain-dead organ donors remains low in France, which may be explained by the increasing proportion of high-risk donors, as well as the mismatch between donor assessment and the transplant team's expectations. Improving donor and donor heart assessment is essential to improve the low utilization rate of available donor hearts without increasing post-transplant recipient mortality. Read More

    Electrocardiographic patterns and long-term training-induced time changes in 2484 elite football players.
    Arch Cardiovasc Dis 2017 Dec 21. Epub 2017 Dec 21.
    Service de cardiologie, institut Lorrain du cœur et des vaisseaux Louis-Mathieu, centre hospitalier universitaire de Nancy, 4, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France.
    Background: High-level physical training induces cardiac structural and functional changes, including 12-lead electrocardiogram modifications.

    Objectives: The purpose of this cross-sectional longitudinal study was to establish a quantitative electrocardiographic profile in highly trained football players. Initial and serial annual electrocardiogram monitoring over subsequent years allowed us to investigate the long-term effects of exercise on cardiac conduction and electrophysiological remodelling. Read More

    Immediate complete revascularization in patients with ST-segment elevation myocardial infarction and multivessel disease treated by primary percutaneous coronary intervention: Insights from the ORBI registry.
    Arch Cardiovasc Dis 2017 Dec 8. Epub 2017 Dec 8.
    CIC-IT 804, service de cardiologie et maladies vasculaires, CHU Pontchaillou, 35000 Rennes, France; Inserm U1099, laboratoire de traitement du signal et de l'image, université de Rennes 1, 35000 Rennes, France.
    Background: Recent studies demonstrated the superiority of complete revascularization (CR) in patients treated by primary percutaneous coronary intervention (pPCI) in ST-elevation myocardial infarction (STEMI).

    Aim: To evaluate whether immediate CR improves in-hospital outcomes in patients with STEMI with multivessel disease.

    Methods: Data from a prospective multicentre registry including 9365 patients with STEMI were analysed. Read More

    Atrial fibrillation: Neurogenic or myogenic?
    Arch Cardiovasc Dis 2018 Jan 8;111(1):59-69. Epub 2017 Dec 8.
    Service de rythmologie, hôpital Louis-Pradel, 28, avenue du Doyen-Lépine, 69500 Bron cedex, France. Electronic address:
    A 55-year-old hypertensive patient presents atrial fibrillation after vasovagal syncope. Non-invasive cardiac workup is normal. Without antiarrhythmic therapy, the patient has no recurrence for the next 3years, then presents with a stroke. Read More

    Is tricuspid annuloplasty increasing surgical mortality and morbidity during mitral valve replacement? A single-centre experience.
    Arch Cardiovasc Dis 2017 Dec 6. Epub 2017 Dec 6.
    Department of cardiology, Bichat hospital, AP-HP, Paris, France; INSERM U1148, Bichat hospital, Paris, France; Faculté de médecine Paris-Diderot, university Paris Diderot, Sorbonne Paris Cité, Paris, France. Electronic address:
    Background: Performance of tricuspid annuloplasty (TA) in patients undergoing mitral valve surgery is recommended based on the degree of tricuspid regurgitation and tricuspid annulus size, but is often underused.

    Aim: To evaluate the impact of combined TA on in-hospital outcome in patients undergoing mitral valve replacement (MVR).

    Methods: We selected all consecutive patients who underwent MVR for native valve disease. Read More


    Electrical storm in the early phase of HeartMateII device implantation: Incidence, risk factors and prognosis.
    Arch Cardiovasc Dis 2017 Dec 4. Epub 2017 Dec 4.
    Service de rythmologie, hôpital cardiologique du Haut-Lévêque, 1, avenue Magellan, 33600 Pessac, France; LIRYC Institute, Inserm 1045, University of Bordeaux, Bordeaux, France.
    Background: Ventricular arrhythmia is common after left ventricular assist device (LVAD) implantation, especially in the early postoperative phase (<30 days).

    Aim: To identify the incidence of and risk factors for electrical storm (ES) occurring within 30 days of HeartMate II implantation.

    Methods: We reviewed data from all consecutive patients undergoing HeartMateII device implantation at our institution from January 2008 to December 2014. Read More

    Cardiopulmonary exercise testing in the evaluation of liver disease in adults who have had the Fontan operation.
    Arch Cardiovasc Dis 2017 Dec 1. Epub 2017 Dec 1.
    University of California San Francisco, San Francisco, CA, USA; Manchester Royal Infirmary, Central Manchester University Hospitals NHS Trust, Manchester, United Kingdom. Electronic address:
    Background: Liver disease (LD) is a long-term complication in patients with a single ventricle who have had the Fontan operation. A decline in cardiopulmonary exercise testing (CPET) variables is associated with increased risk of hospitalization, but its association with LD is unknown.

    Aim: To determine the association between CPET variables and LD in adults who have had the Fontan operation. Read More

    Reaching low-density lipoprotein cholesterol treatment targets in stable coronary artery disease: Determinants and prognostic impact.
    Arch Cardiovasc Dis 2017 Nov 30. Epub 2017 Nov 30.
    U1167, Inserm, Institut Pasteur, université de Lille, CHU de Lille, 59000 Lille, France.
    Background: Low-density lipoprotein cholesterol (LDL-C) reduction is an integral part of the management of patients with coronary artery disease (CAD).

    Aims: To assess attainment of LDL-C goals during long-term treatment of patients with stable CAD, and to determine predictors of goal attainment and the prognostic impact of reaching LDL-C<70mg/dL (1.8mmol/L) in a real-life setting. Read More

    Apixaban in the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation in France: Rationale and design of the PAROS cross-sectional study.
    Arch Cardiovasc Dis 2017 Nov 27. Epub 2017 Nov 27.
    Department of cardiology, hôpital Bichat, AP-HP, Paris, France; FACT, DHU FIRE, Inserm U-1148, LVTS, université Paris-Diderot, Paris, France; Imperial College, Royal Brompton Hospital, London, United Kingdom. Electronic address:
    Background: Atrial fibrillation (AF) is the most common arrhythmia worldwide, and its prevalence is expected to increase with population ageing. The use of vitamin K antagonists (VKAs) for the prevention of stroke and/or systemic embolism in patients with non-valvular atrial fibrillation (NVAF) was recently challenged by non-VKA oral anticoagulants (NOACs), demonstrating a favourable risk-benefit profile, with reductions in stroke, intracranial haemorrhage and mortality, similar major bleeding, but increased gastrointestinal bleeding. Nevertheless, data on their use in a "real-life" setting are scarce for France. Read More

    Cardiovascular anatomy in children with bidirectional Glenn anastomosis, regarding the transcatheter Fontan completion.
    Arch Cardiovasc Dis 2017 Nov 13. Epub 2017 Nov 13.
    Service de cardiologie pédiatrique, centre de référence malformations cardiaques congénitales complexes - M3C, hôpital universitaire Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, 149, rue de Sèvres, 75015 Paris cedex, France; Université Paris V Descartes, 75006 Paris, France. Electronic address:
    Background: Transcatheter stent-secured completion of total cavopulmonary connection (TCPC) after surgical preparations during the Glenn anastomosis procedure has been reported, but complications from this approach have precluded its clinical acceptance.

    Aims: To analyse cardiovascular morphology and dimensions in children with bidirectional Glenn anastomosis, regarding the optimal device design for transcatheter Fontan completion without special surgical "preconditionings".

    Methods: We retrospectively analysed 60 thoracic computed tomography and magnetic resonance angiograms performed in patients with a median age of 4. Read More

    A novel method for localization and ablation of conduction gaps after wide antral circumferential ablation of pulmonary veins.
    Arch Cardiovasc Dis 2017 Nov 10. Epub 2017 Nov 10.
    CHU de Rennes, service de cardiologie et maladies vasculaires, 35000 Rennes, France; Université de Rennes 1, LTSI, 35000 Rennes, France; Inserm, U1099, 35000 Rennes, France.
    Background: Atrial fibrillation ablation is often performed by achieving pulmonary vein isolation using the "wide antral circumferential ablation" (WACA) technique, but many pulmonary veins remain connected because of conduction gaps in the ablation line.

    Aim: To analyse the efficacy of a novel technique based on pacing manoeuvres to detect gaps in an initial WACA lesion.

    Methods: Patients referred for radiofrequency atrial fibrillation ablation were enrolled prospectively. Read More

    National trends in admission for cardiac rehabilitation after a myocardial infarction in France from 2010 to 2014.
    Arch Cardiovasc Dis 2017 Nov 10. Epub 2017 Nov 10.
    The French Public Health Agency, 12, rue du Val-d'Osne, 94410 Saint-Maurice cedex, France.
    Background: Follow-up care and rehabilitation services [soins de suite et réadaptation (SSR)], especially cardiac rehabilitation (CR), constitute a key stage for patients who have had an acute myocardial infarction (AMI).

    Aims: To study admission to SSR, especially for CR, among patients hospitalized for AMI in France in 2014, and its temporal trend between 2010 and 2014.

    Methods: We used the French National Hospital Database to select patients hospitalized with a main diagnosis of AMI (identified by ICD-10 codes I21 to I23) in the first semester of each year from 2010 to 2014. Read More

    Clinical implications of guiding catheter extubation during fractional flow reserve measurements.
    Arch Cardiovasc Dis 2018 Feb 8;111(2):119-125. Epub 2017 Nov 8.
    Centre hospitalier universitaire de Cochin, 27, rue du Faubourg-Saint-Jacques, 74014 Paris, France.
    Background: Fractional flow reserve (FFR) is defined by the maximal coronary flow ratio with and without stenosis.

    Aims: We hypothesized that guiding catheter intubation in coronary ostia during FFR measurements may underestimate FFR value by limiting the increase of coronary flow during maximal hyperaemia.

    Methods: Between June 2013 and January 2014, we prospectively included all patients with i. Read More

    Transfemoral aortic valve implantation is more successful with the Edwards Sapien 3 compared with the Edwards XT for the treatment of symptomatic severe aortic stenosis.
    Arch Cardiovasc Dis 2017 Nov 8. Epub 2017 Nov 8.
    Department of Internal Medicine II - Cardiology, University of Ulm, Ulm, Germany. Electronic address:
    Background: Residual aortic regurgitation (AR) after transfemoral aortic valve implantation (TAVI) is associated with increased mortality. The new Edwards Sapien 3 valve (ES3) is designed to reduce paravalvular AR.

    Aim: To compare a new-generation and a late-generation balloon-expandable transcatheter heart valve. Read More

    The role of platelet reactivity assessment in dual antiplatelet prophylaxis after transcatheter aortic valve implantation.
    Arch Cardiovasc Dis 2017 Nov 7. Epub 2017 Nov 7.
    Intensive Cardiac Therapy Department, Institute of Cardiology, Warsaw, Poland.
    Background: Dual antiplatelet therapy (DAPT) is recommended prophylaxis after transcatheter aortic valve implantation (TAVI). The usefulness of platelet reactivity (PLTR) tests in predicting the safety of periprocedural DAPT in the TAVI population is unknown.

    Aim: To analyze the value of aspirin/clopidogrel PLTR testing in predicting the risk of in-hospital TAVI-related bleeding. Read More

    Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.
    Arch Cardiovasc Dis 2018 Jan 4;111(1):41-52. Epub 2017 Nov 4.
    Institut clinique de la Souris, institut de génétique et de biologie moléculaire et cellulaire, université de Strasbourg, Illkirch, France; Laboratoire de neurobiologie et pharmacologie cardiovasculaire, faculté de médecine, fédération de médecine translationnelle, université, CHU de Strasbourg, 11, rue Humann, 67085 Strasbourg cedex, France. Electronic address:
    Background: Metabolic syndrome is a combination of symptoms including obesity, dyslipidaemia, glucose intolerance and hypertension. Oxidative stress appears to be a pathophysiological factor that links these signs and encourages progression towards heart failure and diabetes. Nox4 is a hydrogen peroxide nicotinamide adenine dinucleotide phosphate (NADPH) oxidase isoform - found in various cardiovascular cells and tissues, but also in tissues such as the liver - which is involved in glucose and lipid homeostasis. Read More

    Pulmonary dysfunction and development of different cardiovascular outcomes in the general population.
    Arch Cardiovasc Dis 2017 Nov 4. Epub 2017 Nov 4.
    Research group, Clinical Epidemiology and Health Services in Stroke, Center for Stroke Research, Charité-Universitätsmedizin Berlin, Charitèplatz 1, 10117, Berlin, Germany. Electronic address:
    Background: Pulmonary dysfunction and cardiovascular disease are major causes of impaired health status in later life, and co-development of these diseases has been reported.

    Aim: To better understand the pathobiology involved in the co-development of these diseases.

    Methods: We investigated the impact of pulmonary dysfunction on the development of cardiovascular disease among people aged≥50 years in the English longitudinal study of ageing (ELSA). Read More

    Time course of secondary mitral regurgitation in patients with heart failure receiving cardiac resynchronization therapy: Impact on long-term outcome beyond left ventricular reverse remodelling.
    Arch Cardiovasc Dis 2017 Oct 25. Epub 2017 Oct 25.
    Cardiology department, GCS-groupement des hôpitaux, institut catholique de Lille, université catholique de Lille, 59000 Lille, France; Inserm U1088, université de Picardie, 59280 Amiens, France. Electronic address:
    Background: The prognostic value of secondary mitral regurgitation (MR) at baseline versus immediately after and several months after cardiac resynchronization therapy (CRT), beyond left ventricular (LV) reverse remodelling, has yet to be investigated.

    Aim: To evaluate the clinical significance of secondary MR before and at two timepoints after CRT in a large cohort of consecutive patients with heart failure (HF) and reduced LV ejection fraction.

    Methods: A total of 198 patients were recruited prospectively into a registry, and underwent echocardiography at baseline and immediately after CRT (on the day of hospital discharge). Read More

    Pregnancy in women with a cardiomyopathy: Outcomes and predictors from a retrospective cohort.
    Arch Cardiovasc Dis 2017 Oct 25. Epub 2017 Oct 25.
    Centre de référence pour les maladies cardiaques héréditaires, hôpital de la Pitié-Salpêtrière, ICAN, AP-HP, 47, boulevard de l'Hôpital, 75013 Paris, France; CESP, Inserm U1018, service de génétique, hôpital Ambroise-Paré, université Versailles-Saint-Quentin, AP-HP, 92100 Boulogne-Billancourt, France. Electronic address:
    Background: Pregnancies in women with pre-existing cardiomyopathies are considered at high risk for complications. However, few data are available to characterize their natural history and predict the outcome.

    Aims: Our aim was to evaluate the prevalence and predictors of acute cardiac and obstetric events in women with a cardiomyopathy during pregnancy, excluding peripartum cardiomyopathy. Read More

    Immediate and 1-year follow-up with the novel nanosurface modified COBRA PzF stent.
    Arch Cardiovasc Dis 2017 Dec 6;110(12):682-688. Epub 2017 Nov 6.
    Department of cardiology, GCS ES-Axium-Rambot, 21, avenue Alfred-Capus, 13090 Aix-en-Provence, France.
    Background: The COBRA PzF coronary stent, which has a unique nano-coating of Polyzene-F, was developed to reduce the risk of stent thrombosis.

    Aims: To report procedural and 1-year clinical outcomes following COBRA PzF coronary stent implantation in a real-world percutaneous coronary intervention (PCI) registry.

    Methods: All patients assigned to treatment with the COBRA PzF in the GCS Axium Rambot Center, Aix-en-Provence, France between February 2013 to June 2014 were prospectively enrolled. Read More

    Quality of life in children participating in a non-selective INR self-monitoring VKA-education programme.
    Arch Cardiovasc Dis 2017 Oct 31. Epub 2017 Oct 31.
    Pediatric Cardiology Department, AP-HP, Necker-Enfants malades, M3C National Reference Center, Paris Descartes University, Sorbonne Paris Cité, Paris, France.
    Background: The quality of life (QoL) of children receiving vitamin K antagonist (VKA) treatment has been scarcely studied.

    Aim: To assess QoL of children, and its evolution, throughout our non-selective international normalized ratio (INR) self-monitoring education programme.

    Methods: Children and parents completed QoL questionnaires (Qualin, PedsQL) during education sessions. Read More

    Reduction of radiation exposure in transcatheter atrial septal defect closure: How low must we go?
    Arch Cardiovasc Dis 2017 Oct 30. Epub 2017 Oct 30.
    Service de cardiologie pédiatrique, centre de référence malformations cardiaques congénitales complexes - M3C, hôpital Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, 149, rue de Sèvres, 75015 Paris cedex, France; Université Paris Descartes, 75006 Paris, France. Electronic address:
    Background: Cardiac catheterization relies on X-ray imaging. Most procedures are now standardized. Interventionists must strive to minimize radiation exposure to reduce the risk of induced cancers. Read More

    Role of tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and associated proteins in coronary artery disease and cardiac events.
    Arch Cardiovasc Dis 2017 Dec 31;110(12):700-711. Epub 2017 Oct 31.
    Northern Ireland centre for stratified medicine, school of biomedical sciences, Ulster university, CTRIC building, Altnagelvin hospital, Glenshane Road, BT47 6SB Londonderry, Northern Ireland; Cardiology department, Western health and social care trust, Altnagelvin hospital, Glenshane road, BT47 6SB Londonderry, Northern Ireland.
    Tumour necrosis factor alpha converting enzyme (TACE/ADAM17) is a member of the A disintegrin and metalloproteinase (ADAM) family of ectodomain shedding proteinases. It regulates many inflammatory processes by cleaving several transmembrane proteins, including tumour necrosis factor alpha (TNFα) and its receptors tumour necrosis factor alpha receptor 1 and tumour necrosis factor alpha receptor 2. There is evidence that TACE is involved in several inflammatory diseases, such as ischaemia, heart failure, arthritis, atherosclerosis, diabetes and cancer as well as neurological and immune diseases. Read More

    Targeting the immune response in atherosclerosis: It's time for clinical trials!
    Arch Cardiovasc Dis 2017 Dec 16;110(12):643-645. Epub 2017 Oct 16.
    Paris-Cardiovascular Research Centre (PARCC), Inserm U970, 56, rue Leblanc, 75737 Paris cedex 15, France; Medical Intensive Care Unit, hôpital Saint-Antoine, université Pierre-et-Marie-Curie, Assistance publique-hopitaux de Paris, Paris, France.

    Prevalence and characteristics of coronary artery disease in heart failure with preserved and mid-range ejection fractions: A systematic angiography approach.
    Arch Cardiovasc Dis 2018 Feb 12;111(2):109-118. Epub 2017 Oct 12.
    Unit of Heart Failure and Valvular Heart Diseases, Department of Cardiology, hôpital Nord, Aix-Marseille University, AP-HM, chemin des Bourrely, 13015 Marseille, France; Mediterranean Association for Research and Studies in Cardiology (MARS Cardio), 13015 Marseille, France. Electronic address:
    Background: Guidelines recommend careful screening and treatment of coronary artery disease (CAD) in heart failure with preserved or mid-range ejection fraction (HFpEF/HFmEF).

    Aim: We aimed to determine the prevalence and characteristics of CAD using a prospective systematic coronary angiography approach.

    Methods: A systematic coronary angiography protocol was applied in consecutive patients admitted for HFpEF/HFmEF during a 6-month period in a single centre. Read More

    Diuretics versus volume expansion in acute submassive pulmonary embolism.
    Arch Cardiovasc Dis 2017 Nov 10;110(11):616-625. Epub 2017 Oct 10.
    Cardiology department, CHU Pasteur, 06000 Nice, France.
    Background: The benefit of volume expansion (VE) in submassive pulmonary embolism (PE) with right ventricular (RV) dysfunction is unclear.

    Aim: To compare the effects of diuretic treatment versus VE in patients hospitalized for PE with RV dysfunction.

    Methods: We prospectively included 46 consecutive patients with submassive PE treated on admission with a 40mg bolus of furosemide (D group, n=24) or 500mL of saline infusion (VE group, n=22). Read More

    Five-year major clinical outcomes according to severity of coronary artery spasm as assessed by intracoronary acetylcholine provocation test.
    Arch Cardiovasc Dis 2017 Oct 10. Epub 2017 Oct 10.
    Department of Medicine, Korea University Graduate School, Seoul, South Korea; Cardiovascular Centre, Korea University Guro Hospital, 148, Gurodong-ro, Guro-gu, Seoul, 08308 South Korea.
    Background: Long-term clinical outcome data according to severity of coronary artery spasm (CAS) as assessed by an intracoronary acetylcholine provocation test are limited in series of Asian patients.

    Aim: To investigate 5-year clinical outcomes in patients with CAS according to CAS severity.

    Methods: In total, 5873 consecutive patients with insignificant coronary artery disease (<70% fixed stenosis) who underwent an acetylcholine provocation test were enrolled and divided into four groups according to CAS severity during the acetylcholine provocation test: negative, borderline positive, moderately positive and severely positive. Read More

    Immediate and midterm results of balloon angioplasty for recurrent aortic coarctation in children aged<1 year.
    Arch Cardiovasc Dis 2017 Oct 10. Epub 2017 Oct 10.
    Paediatric cardiology, Gatien-de-Clocheville children's hospital, university hospital of Tours, 37044 Tours, France; François-Rabelais university, 37000 Tours, France.
    Background: Several publications have considered results of percutaneous angioplasty for aortic recoarctation, but none focused on procedures performed in children aged<1 year.

    Aims: To describe the immediate and midterm results of balloon angioplasty for recoarctation before the age of 1 year, and to define the factors that might influence outcome.

    Methods: We retrospectively reviewed data from 20 consecutive children undergoing percutaneous dilatation for aortic recoarctation before the age of 1 year in the University Hospitals of Tours and Nantes. Read More

    Dosing issues with non-vitamin K antagonist oral anticoagulants for the treatment of non-valvular atrial fibrillation: Why we should not underdose our patients.
    Arch Cardiovasc Dis 2018 Feb 2;111(2):85-94. Epub 2017 Oct 2.
    Department of cardiology, Henri Mondor hospital, AP-HP, Créteil, France.
    Non-vitamin K antagonist oral anticoagulants (NOACs) - dabigatran, rivaroxaban, apixaban and edoxaban - are well established in terms of preventing stroke or systemic embolism in patients with non-valvular atrial fibrillation and high thromboembolism risk. When prescribed incorrectly, NOACs are associated with an increased risk of ischaemic events and bleeding. Current NOAC labels explicitly address dose adjustments according to age, body weight, renal function and concomitant treatment with P-glycoprotein inhibitors. Read More

    Predictors and prognostic impact of new left bundle branch block after surgical aortic valve replacement.
    Arch Cardiovasc Dis 2017 Dec 28;110(12):667-675. Epub 2017 Sep 28.
    Faculté de médecine, université de Rennes 1, 35000 Rennes, France; LTSI Inserm U1099, 35000 Rennes, France.
    Background: Left bundle branch block (LBBB) induces mechanical dyssynchrony that may lead to left ventricular systolic dysfunction.

    Aims: To evaluate the incidence, predictors and clinical impact of new LBBB in patients undergoing surgical aortic valve replacement (SAVR).

    Methods: After exclusion of patients with pre-existing LBBB, a previous pacemaker or a paced rhythm at hospital discharge, 547 consecutive patients undergoing SAVR were included. Read More

    Two-year clinical outcome after a single cryoballoon ablation procedure: A comparison of first- and second-generation cryoballoons.
    Arch Cardiovasc Dis 2017 Oct 25;110(10):543-549. Epub 2017 Sep 25.
    Clinique Ambroise-Paré, 25-27 boulevard Victor-Hugo, 92200 Neuilly-sur-Seine, France.
    Background: The ablation of paroxysmal atrial fibrillation (PAF) by cryoballoon has increased dramatically in recent years. However, there are few data comparing first- and second-generation cryoballoons.

    Aim: To compare safety and mid-term (2-year) efficacy of first- and second-generation cryoballoons in PAF ablation, using cryoballoon size tailored to pulmonary vein anatomy. Read More

    Predictive value of very low frequency at spectral analysis among patients with unexplained syncope assessed by head-up tilt testing.
    Arch Cardiovasc Dis 2018 Feb 27;111(2):95-100. Epub 2017 Sep 27.
    Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
    Background: The role of heart rate variability (HRV) in the prediction of vasovagal syncope during head-up tilt testing (HUTt) is unclear.

    Aim: To evaluate the ability of the spectral components of HRV at rest to predict vasovagal syncope among patients with unexplained syncope referred for HUTt.

    Methods: Twenty-six consecutive patients with unexplained syncope were enrolled in the study. Read More

    Influence of critical closing pressure on systemic vascular resistance and total arterial compliance: A clinical invasive study.
    Arch Cardiovasc Dis 2017 Dec 22;110(12):659-666. Epub 2017 Sep 22.
    Service de physiologie, hôpital de Bicêtre, hôpitaux universitaires Paris-Sud, 94275 Le Kremlin-Bicêtre, France; Université Paris-Sud, 94275 Le Kremlin-Bicêtre, France.
    Background: Systemic vascular resistance (SVR) and total arterial compliance (TAC) modulate systemic arterial load, and their product is the time constant (Tau) of the Windkessel. Previous studies have assumed that aortic pressure decays towards a pressure asymptote (P∞) close to 0mmHg, as right atrial pressure is considered the outflow pressure. Using these assumptions, aortic Tau values of ∼1. Read More

    Changes over time in the prevalence and treatment of cardiovascular risk factors, and contributions to time trends in coronary mortality over 25 years in the Lille urban area (northern France).
    Arch Cardiovasc Dis 2017 Dec 22;110(12):689-699. Epub 2017 Sep 22.
    INSERM U1167 RID-AGE, Pasteur Institute of Lille, Lille, France; Epidemiology Unit, Lille University Medical Centre, MRRC, 2, rue du Pr-Laguesse, 59037 Lille, France; Faculty of Medicine, Lille University, Lille, France. Electronic address:
    Background: The long-term collection of population-based data should improve our knowledge of the contribution of trend in cardiovascular risk factors to the steady fall in mortality associated with coronary heart disease in high-income countries.

    Aims: To assess long-term time trends in the prevalence of cardiovascular risk factors, estimated coronary heart disease risk and mortality between 1986 and 2013 in the Lille urban area (northern France).

    Methods: We studied representative samples of inhabitants of the Lille urban area (aged 40-64 years) in 1986-1988 (n=860), 1995-1996 (n=1021), 2005-2007 (n=1021) and 2011-2013 (n=1636), together with data from the Lille MONICA registry. Read More

    Could anticoagulation avoid bioprosthesis subclinical thrombosis in patients undergoing transcatheter aortic valve replacement?
    Arch Cardiovasc Dis 2018 Jan 21;111(1):25-32. Epub 2017 Sep 21.
    Service de cardiologie, CHU de Nantes-Nord Laennec, boulevard Professeur-Jacques-Monod, -44800 Saint-Herblain, France.
    Background: Despite a lack of clear evidence, current European guidelines recommend antiplatelet therapy after transcatheter aortic valve replacement (TAVR). Recent investigations suggest that bioprosthesis thrombosis after TAVR is not uncommon and may be prevented by anticoagulation, but not by antiplatelet therapy.

    Aims: The study objective was to assess the impact of the antithrombotic regimen on post-TAVR early haemodynamics. Read More

    Definition of indicators of the appropriateness of oral anticoagulant prescriptions in hospitalized adults: Literature review and consensus (PACHA study).
    Arch Cardiovasc Dis 2017 Sep 21. Epub 2017 Sep 21.
    CHU de Bordeaux, place Amélie Raba-Léon, 33000 Bordeaux, France; Centre Inserm U1219 Bordeaux Population Health, université de Bordeaux, ISPED, 33076 Bordeaux, France; Inserm, ISPED, centre Inserm U1219 Bordeaux Population Health, 33076 Bordeaux, France.
    Background: Indicators of the appropriateness of oral anticoagulant prescriptions are lacking, despite the major contribution they could make to improve quality of care.

    Aim: To identify and select such indicators according to their utility and operational implementation.

    Methods: A literature review was conducted to identify indicators of the appropriateness of oral anticoagulant prescriptions according to the guidelines of health authorities and European learned societies. Read More

    Effectiveness of a patient education programme in heart failure with preserved ejection fraction: Results from the ODIN cohort study using propensity score matching.
    Arch Cardiovasc Dis 2018 Jan 22;111(1):5-16. Epub 2017 Sep 22.
    Cardiologie médicale, institut Lorrain-du-Cœur-et-des-Vaisseaux, CHRU de Nancy, Nancy, France.
    Background: Patient education programmes (PEP) are recommended for patients with heart failure but have not been specifically assessed in heart failure with preserved ejection fraction (HFpEF).

    Aim: To assess the effectiveness of a structured PEP in reducing all-cause mortality in patients with HFpEF.

    Methods: Patients with HFpEF were selected from the ODIN cohort, designed to assess PEP effectiveness in patients with HF whatever their ejection fraction, included from 2007 to 2010, and followed up until 2013. Read More

    1 OF 22