11,054 results match your criteria Archives of Biochemistry and Biophysics[Journal]


Salt-Enrichment Impact on Biomass Production in a Natural Population of Peatland Dwelling Arcellinida and Euglyphida (Testate Amoebae).

Microb Ecol 2018 Dec 11. Epub 2018 Dec 11.

Department of Geography, University of Exeter, Exeter, EX4 4RJ, UK.

Unicellular free-living microbial eukaryotes of the order Arcellinida (Tubulinea; Amoebozoa) and Euglyphida (Cercozoa; SAR), commonly termed testate amoebae, colonise almost every freshwater ecosystem on Earth. Patterns in the distribution and productivity of these organisms are strongly linked to abiotic conditions-particularly moisture availability and temperature-however, the ecological impacts of changes in salinity remain poorly documented. Here, we examine how variable salt concentrations affect a natural community of Arcellinida and Euglyphida on a freshwater sub-Antarctic peatland. Read More

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December 2018

[History, purposes and characteristics of medical journals].

Authors:
Humberto Reyes B

Rev Med Chil 2018 Aug;146(8):913-920

Academia Chilena de Medicina, Chile.

Medical journals are fundamental elements in medical education, in professional life, in research and in academic careers. They communicate new scientific and clinical findings, legitimate and give credibility to biomedical and clinical investigation, are guarantors of the authors' intellectual property, are a useful forum for the discussion of relevant topics, distribute selected information to readers and are archives of their publications. Out of the numerous medical journals appeared before and during the XIXth Century, only 24 of them remain active until today and Revista Médica de Chile appears as number 20 in the list. Read More

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Identification of traditional East Asian handmade papers through the multivariate data analysis of pyrolysis-GC/MS data.

Analyst 2018 Dec 11. Epub 2018 Dec 11.

Centre de Recherche sur la Conservation (CRC, USR 3224), Muséum national d'Histoire naturelle, Ministère de la Culture, CNRS, 75005 Paris, France.

An analytical approach based on the multivariate analysis of on-line pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) data is proposed for the identification of traditional East Asian handmade papers from different fiber material origins. This approach utilized several biomarkers detected during the Py-GC/MS analysis of paper samples. At first, the total ion chromatogram (TIC) was taken as the response and then the extracted ion chromatograms (EICs) were considered to improve the discrimination of papers. Read More

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December 2018

Livestock management, beaver, and climate influences on riparian vegetation in a semi-arid landscape.

PLoS One 2018 11;13(12):e0208928. Epub 2018 Dec 11.

US Bureau of Land Management, Vale, Oregon, United States of America.

Riparian and aquatic habitats support biodiversity and key environmental processes in semi-arid and arid landscapes, but stressors such as conventional livestock grazing, wildfire, and drought can degrade their condition. To enhance habitat for fish and wildlife and increase resiliency in these critical areas, land managers in the interior western United States increasingly use alternative grazing strategies, beaver management, or beaver dam surrogates as low-effort, low-expense restoration approaches. In this study we used historical archives of satellite and aerial imagery spanning three decades to characterize riparian vegetation productivity and document beaver dam occurrences, then evaluated vegetation productivity relative to land management associated with livestock grazing and beaver dam densities while accounting for climate and wildfire. Read More

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December 2018

Expected benefit of genomic selection over forward selection in conifer breeding and deployment.

PLoS One 2018 10;13(12):e0208232. Epub 2018 Dec 10.

Scion (New Zealand Forest Research Institute), Rotorua, New Zealand.

Genomic selection is a proven technology in animal and plant breeding to accelerate genetic gain, but as yet is to be fully realised in forest tree breeding. This paper examines, through stochastic simulation, the potential benefits of genomic selection (GS) over forward selection (FS) in a typical conifer breeding program. Methods of speeding the deployment of selected material were also considered, including top-grafting onto mature seed orchard ortets, using additional replicates of clones in archives for crossing, and embryogenesis and clonal propagation. Read More

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December 2018

"The other side of the coin": understanding noninvasive follicular tumor with papillary-like nuclear features in Unifocal and multifocal settings.

Hum Pathol 2018 Dec 7. Epub 2018 Dec 7.

IPATIMUP, Institute of Molecular Pathology and Immunology of University of Porto, Porto, Portugal; I3S, Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal; Department of Pathology, Medical Faculty of Porto University, Porto, Portugal. Electronic address:

The recent description of noninvasive follicular tumor with papillary-like nuclear features (NIFTP) creates several diagnostic and therapeutic challenges for both the pathologist and the attending clinician. Given the concern about overtreatment of these neoplasms, the best way to manage the patients by a surgical procedure and post-surgical follow-up is still under discussion. We aimed to identify predictors of synchronous disease (eg, bilateral cancers) that can influence the appropriate type of surgery and long-term surveillance. Read More

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December 2018

Reappraising localized juvenile spongiotic gingival hyperplasia.

J Am Dent Assoc 2018 Dec 7. Epub 2018 Dec 7.

Background: Localized juvenile spongiotic gingival hyperplasia (LJSGH) is a gingival lesion of unknown cause. The purpose of this study is to present a series of LJSGH cases and compare the findings with the literature.

Methods: After obtaining institutional review board approval, cases of biopsy-proven LJSGH from 2008 through 2018 were retrieved from the University of Pittsburgh Oral Pathology Biopsy Service archives and reviewed. Read More

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December 2018

Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users.

Cochrane Database Syst Rev 2018 Dec 5;12:CD009269. Epub 2018 Dec 5.

BC Centre on Substance Use, BC Centre for Excellence in HIV/AIDS, 611 Powell Street, Vancouver, BC, Canada, V6A 1H2.

Background: Problem alcohol use is common among people who use illicit drugs (PWID) and is associated with adverse health outcomes. It is also an important factor contributing to a poor prognosis among drug users with hepatitis C virus (HCV) as it impacts on progression to hepatic cirrhosis or opioid overdose in PWID.

Objectives: To assess the effectiveness of psychosocial interventions to reduce alcohol consumption in PWID (users of opioids and stimulants). Read More

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December 2018
5 Reads

A dataset of synthetic hexagonal close packed 3D polycrystalline microstructures, grain-wise microstructural descriptors and grain averaged stress fields under uniaxial tensile deformation for two sets of constitutive parameters.

Data Brief 2018 Dec 3;21:1833-1841. Epub 2018 Nov 3.

Carnegie Mellon University, United States.

This data article presents a data set comprised of 54 synthetic 3D equiaxed polycrystalline microstructures, the microstructural descriptors for each grain and the stress fields resulting from two sets of crystal plasticity simulations mimicking uniaxial tensile deformation to a total strain of 2%. This is related to the research article entitled "Applied Machine Learning to predict stress hotspots II: Hexagonal Close Packed Materials" (Mangal and Holm, 2018). The microstructures were created using an open source Dream. Read More

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December 2018
1 Read

Measuring the Social Impact of Nursing Research: An Insight into Altmetrics.

J Adv Nurs 2018 Dec 3. Epub 2018 Dec 3.

The University of Jordan Accreditation and Quality Assurance Center.

Aims: The objectives of this study were to (1) identify nursing journal articles that provoked the most online activity and discussion and (2) assess the association between these articles' altmetric scores and publication characteristics, citation counts; and publishing journals metrics.

Background: Altmetrics, or alternative metrics, have recently emerged as a complementary way of measuring the societal impact of research by assessing the public engagement with research output. To date, no studies have yet investigated the online attention regarding scientific papers published in the nursing field. Read More

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December 2018
2 Reads

Nasal septal abscess: a 10-year retrospective study.

Eur Arch Otorhinolaryngol 2018 Nov 30. Epub 2018 Nov 30.

Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Cheng-Kung Road Section 2, Taipei 114, Taiwan, ROC.

Objective: Nasal septal abscess is an uncommon condition but it can cause potentially life-threatening intracranial complications and cosmetic nasal deformity.

Methods: We analyzed ten years of cases to determine the optimal diagnostic and therapeutic modalities. A retrospective review of case notes from Tri-Service General Hospital archives was performed. Read More

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November 2018
3 Reads

Sources and Resources'The People's Chemists': The Walgreens Boots Alliance Archive.

Soc Hist Med 2018 Nov 26;31(4):857-869. Epub 2018 Apr 26.

School of Government and International Affairs, University of Durham, Al-Qasimi Building, Elvet Hill Road, Durham, UK.

This article explores the historic records of the Walgreens Boots Alliance (WBA) Archive, a repository of over 500,000 items chronicling the over 165-year history of Britain's most famous pharmaceutical retailer. It introduces some of the diverse materials present in the collection that would be of interest to social historians of medicine and pharmacy, particularly highlighting resources pertinent to understanding developments in: the formation of pharmaceutical identity; medical advertising; the internationalisation of pharmaceutical and medical retailing; product research and development; and employee welfare. In the light of the recent launch of the first phase of the Boots online catalogue, the article demonstrates ways in which these records could be utilised to better understand the wider social, cultural and political dynamics at play in the development of medicine, health care and pharmacy in Britain over the long twentieth century. Read More

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November 2018
1 Read

Studying the experience of meditation through Micro-phenomenology.

Curr Opin Psychol 2018 Oct 25;28:54-59. Epub 2018 Oct 25.

Aarhus University, Interacting Minds Centre, Jens Chr. Skous Vej 4, 8000, Aarhus, Denmark.

Numerous scientific studies are conducted on the neurophysiological effects of meditation practices and on the neural correlates of meditative states. However, very few studies have been conducted on the experience associated with contemplative practice: what it is like to meditate - from moment to moment, at different stages of different forms of practice - remains almost invisible in contemporary contemplative science. Recently, 'micro-phenomenological' interview methods have been developed to help us become aware of lived experience and describe it with rigor and precision. Read More

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October 2018
7 Reads

Ads and Labels From Early 20th-Century Health Fraud Promotions.

Authors:
Amber Dushman

AMA J Ethics 2018 Nov 1;20(11):E1082-1093. Epub 2018 Nov 1.

The manager of the American Medical Association's Department of Records Management and Archives in Chicago, Illinois.

Ten advertisements and labels from the American Medical Association (AMA) Historical Health Fraud and Alternative Medicine Collection illustrate false health beliefs perpetuated in 20th-century medical quackery promotions. This article canvasses some of the claims made and responses to these ads and labels. Read More

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November 2018
1 Read

Diagnostic Value of S100p, IMP3, Maspin, and pVHL in the Differantial Diagnosis of Pancreatic Ductal Adenocarcinoma and Normal/chronic Pancreatitis in Fine Needle Aspiration Biopsy.

J Cytol 2018 Oct-Dec;35(4):247-251

Division of Cytopathology, Department of Pathology, Ankara University Faculty of Medicine, Ankara, Turkey.

Introduction: Differentiation between pancreatic ductal adenocarcinoma (PDAC) from benign mimickers is a well-known problem in cytological materials. Recent studies incorporated biological markers into this question and some studies showed that expression of S100P, IMP3, and maspin as well as nonexpression of von Hippel-Lindau gene product (pVHL) were significantly correlated with PDAC. In this study, we aimed to investigate diagnostic value of maspin, IMP3, S100P, and pVHL immunostaining in fine needle aspiration biopsies (FNABs) of pancreatic lesions. Read More

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December 2018
2 Reads

Vaccine-preventable disease control in the People's Republic of China: 1949-2016.

Vaccine 2018 Dec 26;36(52):8131-8137. Epub 2018 Nov 26.

National Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China. Electronic address:

Background: China's immunization program is one of the oldest and largest in the world. Rates of vaccine-preventable diseases (VPD) are comparable to those in high-income countries. The program's evolution has been characterized by ambitious target setting and innovative strategies that have not been widely described. Read More

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December 2018
1 Read

Speaker Gender Representation at the American Society of Anesthesiology Annual Meeting: 2011-2016.

Anesth Analg 2018 Nov 21. Epub 2018 Nov 21.

From the Department of Anesthesiology and Perioperative Medicine.

The American Society of Anesthesiologists (ASA) Annual Meeting is the primary venue for anesthesiologists to present research, share innovations, and build networks. Herein, we describe gender representation for physician speakers at the Annual Meeting relative to the specialty overall. Details of ASA Annual Meeting presentations for individuals and panels were abstracted from the ASA archives for 2011-2016. Read More

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November 2018
1 Read

Murder in the archives: additions to the Sydney Smith Collection.

Authors:
R M Cessford

J R Coll Physicians Edinb 2018 Dec;48(4):371-377

School of Histories, Languages and Cultures, Larkin Building, Cottingham Road, University of Hull, Hull HU6 7RX, UK,

Axes, knives, truncheons and several home-made weapons are some of the feature pieces of a newly deposited collection within the Royal College of Physicians of Edinburgh archive. This paper uses examples from this unusual collection, consisting of 40 weapons and over 400 glass slides, to demonstrate the significance and contribution it has to understanding late 19th- and early 20th-century forensic science and medicine in Scotland. Previously belonging to the late Sir Sydney Smith, these objects and glass slides supplement the Sydney Smith paper collection that contains numerous casefiles spanning his career as a forensic practitioner both in Britain and internationally. Read More

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December 2018
1 Read

Evaluation of radiation-induced cardiac toxicity in breast cancer patients treated with Trastuzumab-based chemotherapy.

Breast Cancer Res Treat 2018 Nov 26. Epub 2018 Nov 26.

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Boston, MA, 02114, USA.

Purpose: Patients with Her2-positive breast cancer treated with trastuzumab have higher rates of cardiotoxicity (CT). Left-breast radiation might increase the risk for CT from cardiac exposure to radiation. The goal of our study is to evaluate the contribution of radiotherapy (RT) in the development of CT in breast cancer patients receiving trastuzumab. Read More

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November 2018
2 Reads

Evolution and extinction of the giant rhinoceros Elasmotherium sibiricum sheds light on late Quaternary megafaunal extinctions.

Nat Ecol Evol 2018 Nov 26. Epub 2018 Nov 26.

Department of Earth Sciences, Natural History Museum, London, UK.

Understanding extinction events requires an unbiased record of the chronology and ecology of victims and survivors. The rhinoceros Elasmotherium sibiricum, known as the 'Siberian unicorn', was believed to have gone extinct around 200,000 years ago-well before the late Quaternary megafaunal extinction event. However, no absolute dating, genetic analysis or quantitative ecological assessment of this species has been undertaken. Read More

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November 2018
1 Read

Prevalence of oral squamous cell carcinoma in Bareilly Region: A seven year institutional study.

J Exp Ther Oncol 2018 Nov;12(4):323-330

Department of Oral and Maxillofacial Pathology, Bareilly International University, Institute of Dental Sciences, Bareilly, (UP), India.

Background: Oral squamous cell carcinoma is a major contributor to disability and death caused by malignant tumors. Variations in social, cultural, and geographic factors affect the tumor behavior and response to treatment. In this study, we undertake a seven years institutional review and analysis of Oral squamous cell carcinoma cases in Bareilly. Read More

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November 2018
2 Reads

Art of listening.

Arch Dis Child 2018 Nov 24. Epub 2018 Nov 24.

--Archives of Disease in Childhood-.

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November 2018
3 Reads

Medical physics workforce: A global perspective.

Phys Med 2018 Nov 22;55:33-39. Epub 2018 Oct 22.

Global Outreach for Radiation Protection, Massachusetts General Hospital & Harvard Medical School, Adjunct Professor of Radiology & Medical Physics, Duke University, Ex-IAEA, Vienna, Austria. Electronic address:

Purpose: The International Organization for Medical Physics (IOMP) performed a detailed study following the first survey published in 2015 with the particular objectives: 1) gather data on global medical physicists (MPs) workforce, 2) identify differences between geographical regions and, 3) investigate whether there is a gender dimension in higher hierarchy positions.

Methods: An online questionnaire was send to IOMP members and contact points in countries where no professional MPs society existed. Information requested: total number (N) of MPs (men and women), N of current elected executive board (EB) of societies and women proportion in the board, president gender and number of women presidents for the last 10 years. Read More

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November 2018
1 Read

Cytopathologic characteristics of HPV-related small cell carcinoma of the oropharynx.

Cancer Cytopathol 2018 Nov 23. Epub 2018 Nov 23.

Department of Pathology and Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background: Human papillomavirus (HPV)-related squamous cell carcinoma (SqCC) of the oropharynx is an epidemiologically and clinically distinct form of SqCC that is associated with an improved prognosis. However, HPV-related small cell carcinoma of the oropharynx is a rare and newly described variant that is associated with aggressive clinical behavior and poor outcomes. To date, fewer than 2 dozen reports of this entity exist in the literature, and there is no discussion of cytopathologic features. Read More

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November 2018
4 Reads

TIRADS Interobserver Variability Among Indeterminate Thyroid Nodules: A Single-Institution Study.

J Ultrasound Med 2018 Nov 22. Epub 2018 Nov 22.

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Objectives: A high proportion of cytologically indeterminate, Afirma Gene Expression Classifier "suspicious" thyroid nodules are benign. The Thyroid Imaging Reporting and Data System (TIRADS), was proposed by the American College of Radiology in 2017 to help classify thyroid nodules based on ultrasound characteristics in a standardized fashion to guide management. We aim to determine the interobserver variability of TIRADS classification among cytologically indeterminate and Afirma suspicious nodules. Read More

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November 2018
1 Read

Climate Regimes Override Micro-Site Effects on the Summer Temperature Signal of Scots Pine at Its Northern Distribution Limits.

Front Plant Sci 2018 8;9:1597. Epub 2018 Nov 8.

Institute of Botany and Landscape Ecology, University of Greifswald, Greifswald, Germany.

Tree growth at northern boreal treelines is generally limited by summer temperature, hence tree rings serve as natural archives of past climatic conditions. However, there is increasing evidence that a changing summer climate as well as certain micro-site conditions can lead to a weakening or loss of the summer temperature signal in trees growing in treeline environments. This phenomenon poses a challenge to all applications relying on stable temperature-growth relationships such as temperature reconstructions and dynamic vegetation models. Read More

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November 2018
2 Reads

Establishment of an article transfer service for Archives of Plastic Surgery.

Authors:
Younsang Cho

Arch Plast Surg 2018 Nov 15;45(6):493-494. Epub 2018 Nov 15.

Technical Manager, Archives of Plastic Surgery M2community, Seoul, Korea.

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November 2018
2 Reads

Mortality Characteristics of Two Populations in the Northern Mediterranean (Croatia) in the Period 1960⁻2012: An Ecological Study.

Int J Environ Res Public Health 2018 Nov 20;15(11). Epub 2018 Nov 20.

Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia.

In the second half of the 20th century, the town of Bakar (Primorje-Gorski Kotar County, Croatia), where a coking plant was operational 1978⁻1994, experienced intensive industrialisation. The town of Mali Lošinj (Primorje-Gorski Kotar County, Croatia) in this period based its economy on non-industrial sectors. The study goal was comparing mortality characteristics of these populations in the northern Mediterranean for 1960⁻2012. Read More

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November 2018
2 Reads

Spatial and temporal distribution of heavy metal concentrations and enrichment in the southern Gulf of Mexico.

Sci Total Environ 2019 Feb 10;651(Pt 2):3174-3186. Epub 2018 Oct 10.

Unidad Académica de Ecología y Biodiversidad Acuática, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, 04510 Ciudad de México, Mexico. Electronic address:

Trace element (As, Co, Cr, Cu, Ni, Pb, V and Zn) enrichment trends during the past century, were assessed in thirteen Pb-dated sediment cores from the southern Gulf of Mexico, with the purpose to evaluate the impact on the environment, and potentially on public health, of the offshore oil industry and of oil spills such as that of the Ixtoc1 well blowout in 1979. The trace element composition was quite homogeneous among cores; and the pre-industrial concentrations of Ba, Cr, Cu and Ni are naturally high in the region, as to reach levels of potential ecological concern. The influence of multiple and simultaneous processes (e. Read More

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February 2019
1 Read

Department of Public Health Nursing.

Authors:

Am J Nurs 2018 Dec;118(12):68-69

Editor's note: From its first issue in 1900 through to the present day, AJN has unparalleled archives detailing nurses' work and lives over more than a century. These articles not only chronicle nursing's growth as a profession within the context of the events of the day, but they also reveal prevailing societal attitudes about women, health care, and human rights. Today's nursing school curricula rarely include nursing's history, but it's a history worth knowing. Read More

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December 2018
5 Reads

Multi-drug resistance protein 2 (MRP2) expression, adjuvant tamoxifen therapy, and risk of breast cancer recurrence: a Danish population-based nested case-control study.

Acta Oncol 2018 Nov 20:1-7. Epub 2018 Nov 20.

a Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.

Background: Adjuvant tamoxifen therapy approximately halves the risk of recurrence in estrogen receptor-positive (ER+) breast cancer patients, but many women respond insufficiently to therapy. Expression of multi-drug resistance protein 2 (MRP2) in breast cancer may potentiate tamoxifen resistance. Thus, we investigated the expression of MRP2 in breast cancer as a predictor of tamoxifen therapy effectiveness. Read More

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November 2018
2 Reads

"An Error in An Old Paper Illustrates the Need for Data/Code Archives".

Authors:
B D McCullough

J Clin Epidemiol 2018 Nov 17. Epub 2018 Nov 17.

Department of Decision Sciences & MIS Drexel University, Philadelphia, PA, 19104. Electronic address:

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November 2018
1 Read

Footprints from the past: The influence of past human activities on vegetation and soil across five archaeological sites in Greenland.

Sci Total Environ 2018 Nov 8;654:895-905. Epub 2018 Nov 8.

Center for Permafrost (CENPERM), Department of Geosciences and Natural Resource Management, University of Copenhagen, Øster Voldgade 10, DK-1350 Copenhagen K. Denmark. Electronic address:

Climate change has irrevocable consequences for the otherwise well-preserved archaeological deposits in the Arctic. Vegetation changes are expected to impact archaeological sites, but currently the effects are poorly understood. In this article we investigate five archaeological sites and the surrounding natural areas along a climate gradient in Southwest Greenland in terms of vegetation types, above- and below-ground biomass, soil geochemistry and spectral properties. Read More

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November 2018
4 Reads

Targeted sequencing of Plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations.

Hum Pathol 2018 Nov 14. Epub 2018 Nov 14.

Department of Pathology, Johns Hopkins University, Baltimore, MD, United States 21287; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, United States 35249. Electronic address:

Activating mutations in the promoter of the telomerase reverse transcriptase (TERT) gene are the most common genetic alterations in urothelial carcinoma (UC) of the bladder and upper urinary tract. While the cadherin 1 (CDH1) gene is commonly mutated in the clinically aggressive plasmacytoid variant of urothelial carcinoma (PUC), little is known about their TERT promoter mutation status. A retrospective search of our archives for PUC and UC with plasmacytoid and/or signet ring cell features (2007-2014) was performed. Read More

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November 2018
6 Reads

The State Scientific Automated Medical Registry, Kazakhstan: an important resource for low-dose radiation health research.

Radiat Environ Biophys 2018 Nov 16. Epub 2018 Nov 16.

International Agency for Research on Cancer, 150 Cours Albert Thomas, 96372, Lyon Cedex 08, France.

Direct quantitative assessment of health risks following exposure to ionizing radiation is based on findings from epidemiological studies. Populations affected by nuclear bomb testing are among those that allow such assessment. The population living around the former Soviet Union's Semipalatinsk nuclear test site is one of the largest human cohorts exposed to radiation from nuclear weapons tests. Read More

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November 2018
3 Reads

A systematic review of adherence to oral pre-exposure prophylaxis for HIV - how can we improve uptake and adherence?

BMC Infect Dis 2018 Nov 16;18(1):581. Epub 2018 Nov 16.

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.

Introduction: Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure prophylaxis is highly dependent on user adherence, which some previous trials have struggled to optimise particularly in low and middle income settings. This systematic review aims to ascertain the reasons for non-adherence to pre-exposure prophylaxis to guide future implementation. Read More

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November 2018
4 Reads

The European Bioinformatics Institute in 2018: tools, infrastructure and training.

Nucleic Acids Res 2018 Nov 16. Epub 2018 Nov 16.

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

The European Bioinformatics Institute (https://www.ebi.ac. Read More

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November 2018
8 Reads

Genetic architecture of hippocampal subfields on standard resolution MRI: How the parts relate to the whole.

Hum Brain Mapp 2018 Nov 15. Epub 2018 Nov 15.

Department of Psychiatry, University of California San Diego, San Diego, California.

The human hippocampus can be subdivided into subfields with unique functional properties and differential vulnerability to disease or neuropsychiatric conditions. Identifying genes that confer susceptibility to such processes is an important goal in developing treatments. Recent advances in automatic subfield segmentation from magnetic resonance images make it possible to use these measures as phenotypes in large-scale genome-wide association studies. Read More

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November 2018
4 Reads

Drug Shortages From the Perspectives of Authorities and Pharmacy Practice in the Netherlands: An Observational Study.

Front Pharmacol 2018 31;9:1243. Epub 2018 Oct 31.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.

Drug shortages are a potential threat to public health. Reliable data on drug shortages is limited. The objective was to examine the extent and nature of potential drug shortages signaled by authorities and pharmacy practice in the Netherlands The primary working systems of Dutch authorities (Medicines Evaluation Board and Health and Youth Care Inspectorate) and the archives of pharmacy practice (Royal Dutch Pharmacists Association) from 2012 to 2015 were searched for number, characteristics, overlap, and date of signals on potential drug shortages. Read More

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October 2018
10 Reads

Correlation between tooth size-arch length discrepancy and interradicular distances measured on CBCT and panoramic radiograph: an evaluation for miniscrew insertion.

Dental Press J Orthod 2018 Sep-Oct;23(5):39.e1-39.e13

Aarhus University, Faculty of Health, Department of Dentistry and Oral Health, Section of Orthodontics (Aarhus, Denmark).

Introduction: The selection of appropriate sites for miniscrew insertion is critical for clinical success.

Objectives: The aim of the present study was to evaluate how interradicular spaces measured on panoramic radiograph compare with Cone-Beam Computed Tomography (CBCT), and how crowding can influence the presence of available space for miniscrew insertion, in order to define a new "safe zones" map.

Methods: A total of 80 pre-treatment panoramic radiographs and 80 CBCT scans with corresponding digital models were selected from the archives of the department of Dentistry, Aarhus University. Read More

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June 2017
3 Reads

Primary Lung Tumors in Children: Radiologic-Pathologic Correlation From the Radiologic Pathology Archives.

Radiographics 2018 Nov-Dec;38(7):2151-2172

From the Department of Radiology and Radiological Sciences (J.P.L., E.M.C.) and Department of Pathology (J.P.L., A.R.H., E.M.C.), Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814; Thoracic Radiology Section (J.P.L., D.M.B.) and Pediatric Radiology Section (D.M.B., E.M.C.), American Institute for Radiologic Pathology, Silver Spring, Md; Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (D.M.B.); Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, Tex (B.W.C.); and Department of Radiology, Walter Reed National Military Medical Center, Bethesda, Md (M.A.P.).

Primary lung tumors in children are rare, with a narrow range of diagnostic considerations. However, the overlapping imaging appearances of these tumors necessitate attention to key discriminating imaging and pathologic features. In the neonate and infant, the important considerations include pleuropulmonary blastoma (PPB), infantile fibrosarcoma, and fetal lung interstitial tumor. Read More

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November 2018
2 Reads

[The investigation on the historical remains related to medical, healthy and hygienical activities in Zhejiang].

Authors:
D M Zhu

Zhonghua Yi Shi Za Zhi 2018 Jul;48(4):221-227

College of Basic Medical Sciences of Zhejiang Chinese Medical University, Hangzhou, 310053 China.

Aiming to protect and utilize the historical remains related to medical, healthy, and hygienical activities, we have to get the information of those remains. From 2003 to 2018, we investigated and documented those remains before 1949 by checking various literatures, archives, and collected the information supplied by the traditional Chinese medicine practitioners and scholars. Total remains 167 recorded and documented as following: historical event remains 17; temple and shrine 12; medical institutions remains 43; research institutions remains 2; traditional Chinese medical factory remains 1; western and traditional Chinese medicine stores 15; western and Chinese medical education institutions remains 5; famous medical person residence remains 16; tombs 14; inscription 7; sites of wells 35, also including 1950s historical remains 2. Read More

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July 2018
3 Reads

Clinicopathologic features of Anaplastic Myxopapillary Ependymomas.

Brain Pathol 2018 Nov 12. Epub 2018 Nov 12.

Department of Pathology, University of California, San Francisco, CA.

Myxopapillary ependymomas (MPE) are considered benign (WHO grade I) neoplasms with favorable prognosis. However, malignant behavior occurs in a small subset. To our knowledge, only five anaplastic MPEs have been reported without consensus on diagnostic criteria. Read More

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November 2018
6 Reads
3.840 Impact Factor

The association between the ultrasonography TIRADS classification system and surgical pathology among indeterminate thyroid nodules.

Surgery 2019 Jan 8;165(1):69-74. Epub 2018 Nov 8.

Department of Surgery, University of Virginia School of Medicine, Charlottesville, VA. Electronic address:

Background: A high proportion of cytologically indeterminate, Afirma-suspicious thyroid nodules are benign. The Thyroid Imaging Reporting and Data System was proposed by the American College of Radiology in 2015 to determine appropriate management of thyroid nodules in a standardized fashion. Our aim was to determine the diagnostic value of the Thyroid Imaging Reporting and Data System in cytologically indeterminate and Afirma-suspicious nodules. Read More

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January 2019
1 Read

The fake unlocked femoral nail: A configuration to avoid in stable pertrochanteric femur fractures.

Injury 2018 Nov;49 Suppl 3:S32-S36

School of Medicine, University of Bari "Aldo Moro", AOU Policlinico Consorziale, Department of Basic Medical Sciences, Neuroscience and Sense Organs, Orthopaedic & Trauma Unit, Bari, Italy.

Background: Intramedullary unlocked nailing is a safe and used treatment for stable pertrocantheric fractures. Due to the femoral anterior bow of the shaft or a wrong entry point, the distal tip of the nail can be impinging the anterior cortex. This type of situation can compromise the function of the nail, leading to nonunion of the fracture, and cut-out. Read More

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November 2018
4 Reads

Evaluation of long-term estuarine vegetation changes through Landsat imagery.

Sci Total Environ 2018 Oct 31;653:512-522. Epub 2018 Oct 31.

CESAM - Centre for Environmental and Marine Studies, Physics Department, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal.

Salt marshes support estuarine biodiversity and provide ecosystem services; however, their general decay is being observed worldwide, in large part due to land reclamation. Accordingly, there is a growing concern about salt marsh preservation status having in mind the promotion of effective management decisions towards their conservation and restoration. Satellite imagery offers the opportunity to monitor land surface dynamics, constituting a fundamental information source for wetland monitoring. Read More

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October 2018
10 Reads

Approaches for creating comparable measures of alcohol use symptoms: Harmonization with eight studies of criminal justice populations.

Drug Alcohol Depend 2018 Oct 23;194:59-68. Epub 2018 Oct 23.

Yale School of Medicine, United States. Electronic address:

Background: With increasing data archives comprised of studies with similar measurement, optimal methods for data harmonization and measurement scoring are a pressing need. We compare three methods for harmonizing and scoring the AUDIT as administered with minimal variation across 11 samples from eight study sites within the STTR (Seek-Test-Treat-Retain) Research Harmonization Initiative. Descriptive statistics and predictive validity results for cut-scores, sum scores, and Moderated Nonlinear Factor Analysis scores (MNLFA; a psychometric harmonization method) are presented. Read More

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October 2018
7 Reads

The Jewish doctors involved in the development of health resorts in eastern Galicia at the late 19th and early 20th century (Central and Eastern Europe).

Wien Klin Wochenschr 2018 Nov 7;130(21-22):680-685. Epub 2018 Nov 7.

Institute of Biology, Faculty of Biology and Animal Science, Wrocław University of Environmental and Life Sciences, Kożuchowska 5b, 51-631, Wrocław, Poland.

Background: The involvement of Jewish doctors and scientists in the development of health resorts in eastern Galicia (part of the Austrian monarchy after 1772, and since 1918 as part of independent Poland, now part of Ukraine) is unquestionable; however, awareness of this fact is not that common. Meanwhile, also due to their work and activity, small borderland resorts became important medical, cultural and social centers of the region. The involvement of Jewish doctors in the development of Galician health resorts resulted from, among others, the rich and multi-layered tradition and integration of Judaism with the hygiene regulations and moral principles of the religion. Read More

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November 2018
10 Reads

Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes.

Front Immunol 2018 22;9:2332. Epub 2018 Oct 22.

Surgery-Transplant, University of Nebraska Medical Center, Omaha, NE, United States.

We analyzed T cell subsets from cryopreserved PBMC obtained from the TrialNet Pathway to Prevention archives. We compared subjects who had previously seroconverted for one or more autoantibodies with non-seroconverted, autoantibody negative individuals. We observed a reduced frequency of MAIT cells among seroconverted subjects. Read More

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October 2018
6 Reads