12,161 results match your criteria Archives Of Mechanics[Journal]


Yottixel - An Image Search Engine for Large Archives of Histopathology Whole Slide Images.

Med Image Anal 2020 Jun 24;65:101757. Epub 2020 Jun 24.

University of Pittsburgh Medical Center, Department of Pathology, PA, USA.

With the emergence of digital pathology, searching for similar images in large archives has gained considerable attention. Image retrieval can provide pathologists with unprecedented access to the evidence embodied in already diagnosed and treated cases from the past. This paper proposes a search engine specialized for digital pathology, called Yottixel, a portmanteau for "one yotta pixel," alluding to the big-data nature of histopathology images. Read More

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http://dx.doi.org/10.1016/j.media.2020.101757DOI Listing

Plexiform Myofibroblastoma: Clinicopathologic Analysis of 36 Cases of a Distinctive Benign Tumor of Soft Tissue Affecting Mainly Children and Young Adults.

Am J Surg Pathol 2020 Jun 30. Epub 2020 Jun 30.

Department of Pathology, Brigham and Women's Hospital.

The spectrum of benign superficial fibroblastic/myofibroblastic tumors continues to expand and includes entities such as plexiform fibrohistiocytic tumor, dermatomyofibroma and fibroblastic connective tissue nevus. Here, we describe a seemingly distinctive group of lesions which we have labeled "plexiform myofibroblastoma" (PM). PM is a rare superficial mesenchymal tumor of fibroblastic/myofibroblastic lineage that predominantly occurs in children and young adults. Read More

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http://dx.doi.org/10.1097/PAS.0000000000001534DOI Listing

Influences for Gender Disparity in Academic Family Medicine in North American Medical Schools.

Cureus 2020 May 30;12(5):e8368. Epub 2020 May 30.

Radiology, Vancouver General Hospital, Vancouver, CAN.

Background Women physicians continue to comprise the minority of leadership roles in Academic Family Medicine (AFM) faculty across North American medical schools. Our study quantified the current state of gender disparity by analyzing academic position, leadership ranking, and research productivity. Methods We generated a database for 6,746 AFM faculty members. Read More

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http://dx.doi.org/10.7759/cureus.8368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326302PMC

The Nottingham and Nottinghamshire Hospital for Diseases of the Throat, Ear and Nose (1886-1947): its formation, rise and demise.

Authors:
P J Bradley

J Laryngol Otol 2020 Jul 3:1-5. Epub 2020 Jul 3.

Department of Otorhinolaryngology, Head and Neck Surgery, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, UK.

Background: The Nottingham and Nottinghamshire Hospital for Diseases of the Throat, Ear and Nose existed in Nottingham for over 60 years, but there is little knowledge or documentation regarding its existence.

Methods: The following resources were searched to find out more about the hospital: the Nottinghamshire Archives; Manuscripts and Special Collections at the University of Nottingham Libraries; and Nottingham Central Library. Information was also obtained from the founders' relatives. Read More

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http://dx.doi.org/10.1017/S0022215120001322DOI Listing

[Men in Closed Venerological Wards of the GDR illustrated by Examples of Berlin, Dresden and Erfurt].

Gesundheitswesen 2020 Jul 1. Epub 2020 Jul 1.

Institut für Geschichte, Theorie und Ethik der Medizin, Universität Ulm, Ulm.

Objectives: While numerous research results are available on the treatment of women in closed venereological wards in the GDR, hardly anything is known about the forced admissions of men to these wards. The aim of this study was to analyse construction of the wards, the admission and maintenance in the wards as well as the extent of the compulsory admissions of men.

Methods: Unprinted sources were researched in the Federal Archive and State Archive Berlin and in the municipal archives of Erfurt and Zwickau and analyzed using a historically critical method. Read More

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http://dx.doi.org/10.1055/a-1186-0075DOI Listing

Cerebral schistosomiasis: MRI features with pathological correlation.

Acta Radiol 2020 Jun 30:284185120934475. Epub 2020 Jun 30.

Department of Radiology, Sichuan University West China Hospital, Chengdu, Sichuan, PR China.

Background: Neuroschistosomiasis is not commonly encountered and is probably underrecognized. We hope these findings can help clinicians and radiologists to raise awareness of this disabling disorder.

Purpose: To demonstrate the magnetic resonance imaging (MRI) findings of cerebral schistosomiasis and correlate it with pathological findings. Read More

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http://dx.doi.org/10.1177/0284185120934475DOI Listing

Melanoma and non-melanoma skin cancer among patients who attended at King Khalid University Hospital in Riyadh, Saudi Arabia from 2007 - 2018.

Saudi Med J 2020 Jul;41(7):709-714

Division of Plastic Surgery, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia. E-mail.

Objectives: To assess the prevalence of melanoma and non-melanoma skin cancer for patients attended King Khalid University Hospital, Riyadh, Saudi Arabia. We are also assessing the most common category of skin cancer to be encountered among those patients. Methods: The authors conducted a retrospective study including all patients (Saudi and non-Saudi) who attended King Khalid University Hospital (KKUH) at the period of (2007-2018). Read More

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http://dx.doi.org/10.15537/smj.2020.7.25138DOI Listing

Role of platelets in neonatal necrotizing enterocolitis.

Authors:
Akhil Maheshwari

Pediatr Res 2020 Jun 29. Epub 2020 Jun 29.

Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Necrotizing enterocolitis (NEC) is an inflammatory bowel necrosis of premature infants and is a leading cause of morbidity and mortality in infants born between 23 and 28 weeks of gestation. Fifty to 95% of all infants with NEC develop thrombocytopenia (platelet counts <150 × 10/L) within 24-72 h of receiving this diagnosis. In many patients, thrombocytopenia is severe and is treated with one or more platelet transfusions. Read More

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http://dx.doi.org/10.1038/s41390-020-1038-8DOI Listing

Predictors of filing claims and receiving compensation in malignant mesothelioma patients.

Health Policy 2020 Jun 10. Epub 2020 Jun 10.

Occupational and Environmental Medicine, Epidemiology and Hygiene Department, Italian Workers' Compensation Authority (INAIL), Via Stefano Gradi, 55, 00143 Rome, Italy.

Although the predominant occupation origin of mesothelioma is well known, determinant factors involved in filing compensation are scarcely investigated. A linkage between incident mesothelioma cases collected by Italian mesothelioma register (ReNaM) and compensation claims and assignment by Italian national insurance Institute (INAIL) has been conducted for cases diagnosed in the period 2010-2015 and occupational exposure to asbestos. Logistic regression models and decision tree models have been used to identify demographic, diagnostic and anamnestic factors significant for filing and receiving compensation. Read More

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http://dx.doi.org/10.1016/j.healthpol.2020.06.005DOI Listing

Resolving atmospheric mercury loading and source trends from isotopic records of remote North American lake sediments.

Environ Sci Technol 2020 Jun 27. Epub 2020 Jun 27.

The strongest evidence for anthropogenic alterations to the global mercury (Hg) cycle comes from historical records of mercury deposition preserved in lake sediments. Hg isotopes have added a new dimension to these sedimentary archives, promising additional insights into Hg source apportionment and biogeochemical processing. Presently, most interpretations of historical changes are constrained to a small number of locally contaminated ecosystems. Read More

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http://dx.doi.org/10.1021/acs.est.0c00579DOI Listing

The Rock of Gibraltar: The Value of Mentorship in the Early Years (Dr. Virginia Apgar and Dr. Ralph Waters).

J Anesth Hist 2020 Jun 9;6(2):49-53. Epub 2019 Sep 9.

Department of Anesthesiology, University of Mississippi, Oxford, MS.

Behind every successful physician there are mentors to light the path. Ralph Waters, founder of the anesthesiology residency at the University of Wisconsin-Madison, was an instrumental part of Virginia Apgar's success; his support of her education and promotion of her professional endeavors proved to shape the medical powerhouse that Apgar would become. In this article, we learn about the professional and personal relationship between Waters and Apgar through personal correspondence from the Ralph Waters Collection at University of Wisconsin Archives, scientific publications, and meeting records. Read More

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http://dx.doi.org/10.1016/j.janh.2019.08.005DOI Listing

Paediatrics in Theresienstadt ghetto.

Cent Eur J Public Health 2020 Jun;28(2):155-160

Faculty of Education, Comenius University, Bratislava, Slovak Republic.

The main objective of this study is to describe the most common childhood diseases occurring in the Theresienstadt ghetto during the Second World War as well as applied anti-epidemic measures. A partial objective is to describe medical and nursing care of sick child prisoners. The data was obtained by the method of synthesis of primary and secondary data with the highest importance after adequate external source criticism using selected monographs, memoirs, survivor diaries, Orders of the day by the Council of the Elders and Reports of the Jewish self-government of the Theresienstadt ghetto from 1941 to 1945, the Archives of the Jewish Museum in Prague, the Ghetto Museum, the Museum of the History of Polish Jews in Warsaw, Post Bellum online electronic collection of oral historical interviews, and witness accounts. Read More

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http://dx.doi.org/10.21101/cejph.a5557DOI Listing

Gynecologic Risk Mitigation Considerations for Long-Duration Spaceflight.

Aerosp Med Hum Perform 2020 Jul;91(7):543-564

As NASA and its international partners, as well as the commercial spaceflight industry, prepare for missions of increasing duration and venturing outside of low-Earth orbit, mitigation of medical risk is of high priority. Gynecologic considerations constitute one facet of medical risk for female astronauts. This manuscript will review the preflight, in-flight, and postflight clinical evaluation, management, and prevention considerations for reducing gynecologic and reproductive risks in female astronauts. Read More

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http://dx.doi.org/10.3357/AMHP.5538.2020DOI Listing

Absence of BRAFV600E Immunohistochemical Expression in Sporadic Odontogenic Keratocyst, Syndromic Odontogenic Keratocyst and Orthokeratinized Odontogenic Cyst.

J Oral Pathol Med 2020 Jun 26. Epub 2020 Jun 26.

Department of Oral Pathology and Microbiology, Nair Hospital Dental College, Mumbai, 400008, India.

Background: Odontogenic keratocyst (OKC) is a unique developmental odontogenic cyst that has the potential to behave aggressively, and is associated with the nevoid basal cell carcinoma syndrome. Orthokeratinized odontogenic cyst (OOC) is a distinct, uncommon odontogenic cyst. It significantly differs from OKC not only in its epithelial lining but also in proliferating kinetics, clinical, immunohistochemical and biological behaviour. Read More

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http://dx.doi.org/10.1111/jop.13081DOI Listing

Open modeling and exchange (OMEX) metadata specification version 1.0.

J Integr Bioinform 2020 Jun 25. Epub 2020 Jun 25.

Humboldt University Berlin, Berlin, Germany.

A standardized approach to annotating computational biomedical models and their associated files can facilitate model reuse and reproducibility among research groups, enhance search and retrieval of models and data, and enable semantic comparisons between models. Motivated by these potential benefits and guided by consensus across the COmputational Modeling in BIology NEtwork (COMBINE) community, we have developed a specification for encoding annotations in Open Modeling and EXchange (OMEX)-formatted archives. Distributing modeling projects within these archives is a best practice established by COMBINE, and the OMEX metadata specification presented here provides a harmonized, community-driven approach for annotating a variety of standardized model and data representation formats within an archive. Read More

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http://dx.doi.org/10.1515/jib-2020-0020DOI Listing

[That daily trickle of death: Infant mortality and the dawn of pediatric medicine in the province of Santiago, Chile, 1870-1913].

Salud Colect 2020 May 16;16:e2727. Epub 2020 May 16.

Doctor en Historia. Profesor Adjunto e Investigador, Centro de Estudios Históricos, Universidad Bernardo O'Higgins; Santiago, Chile.

This article deals with the problem of infant mortality in Santiago, Chile, and the development of pediatric medicine during the second half of the nineteenth century and the beginning of the twentieth century. Emphasis is placed on the specialists who contributed to organizing the knowledge and practices that structured their professional field. In order to pursue the objective and systematize this new medical field, our analysis suggests the decisive role of the establishment of the Faculty of Medicine and the appearance of coursework dedicated specifically to childhood diseases. Read More

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http://dx.doi.org/10.18294/sc.2020.2727DOI Listing

Quality of Otology and Neurotology Research in Otolaryngology Journals.

Otol Neurotol 2020 Jun 19. Epub 2020 Jun 19.

Otolaryngology-Head & Neck Surgery.

Objective: To identify trends in the quality of otology studies published in general otolaryngology journals over a 20-year period.

Study Design: Retrospective analysis.

Methods: Otologic and neurotologic papers from 1997, 2007, and 2017 were identified in the three general otolaryngology journals with the highest Eigenfactor scores: the Laryngoscope, European Archives of Otorhinolaryngology, and Otolaryngology-Head and Neck Surgery. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002731DOI Listing

Risk for Nephrogenic Systemic Fibrosis After Exposure to Newer Gadolinium Agents: A Systematic Review.

Ann Intern Med 2020 Jun 23. Epub 2020 Jun 23.

Duke University School of Medicine and Durham Veterans Affairs Health Care System, Durham, North Carolina (J.W.W., K.M.G.).

Background: The risk for nephrogenic systemic fibrosis (NSF) after exposure to newer versus older gadolinium-based contrast agents (GBCAs) remains unclear.

Purpose: To synthesize evidence about NSF risk with newer versus older GBCAs across the spectrum of kidney function.

Data Sources: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Web of Science for English-language references from inception to 5 March 2020. Read More

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http://dx.doi.org/10.7326/M20-0299DOI Listing

A clinicopathologic analysis of 135 cases of cemento-osseous dysplasia: To operate or not to operate?

J Stomatol Oral Maxillofac Surg 2020 Jun 18. Epub 2020 Jun 18.

Istanbul University, Institute of Oncology, Department of Tumour Pathology, Istanbul, Turkey. Electronic address:

Purpose: The aim of this retrospective study was to investigate the characteristics of cemento-osseous dysplasia (COD) lesions for devising a clinical algorithm to help management decisions, specifically discussing the need for a possible surgical intervention versus solely follow-up.

Materials And Methods: One hundred thirty-five subjects were thus identified having previously diagnosed and treated for COD from the archives of the pathology in between 2005-2015. These were then re-evaluated. Read More

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http://dx.doi.org/10.1016/j.jormas.2020.06.002DOI Listing

[From Chinese Medical Association Medical History Museum to the Shanghai Museum of Traditional Chinese Medicine: commemoration of the 130th anniversary of the birthday of modern medical historian Wang Jimin].

Authors:
L L Wang L Y Chen

Zhonghua Yi Shi Za Zhi 2019 Nov;49(6):343-349

Institute of Science, Technology and Humanities, SHUTCM, Shanghai 201203, China.

The Shanghai Museum of Traditional Chinese Medicine, formerly known as the Chinese Medical Association Medical History Museum, is the first professional medical history museum in China. Wang Jimin is the main planner and founder of the Medical History Museum of the Chinese Medical Association and served as the first curator. In 1951, the Chinese Medical Association moved to Beijing, and the Medical History Museum stayed in Shanghai. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0255-7053.2019.06.003DOI Listing
November 2019

Mapping of atmospheric heavy metal deposition in Guangzhou city, southern China using archived bryophytes.

Environ Pollut 2020 Jun 11;265(Pt B):114998. Epub 2020 Jun 11.

School of Environmental Science and Engineering, Guangzhou University, Guangzhou, 510006, China. Electronic address:

Atmospheric heavy metal contamination is becoming a serious threat to environmental and human health in Chinese megacities. This study evaluated the concentrations of arsenic (As), cadmium (Cd), copper (Cu), lead (Pb) and zinc (Zn) and Pb isotopic compositions in herbarium and native bryophytes collected from Guangzhou from 1932 to 2018. Relatively low mean metal concentrations were measured for bryophytes collected in the 1930s. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.114998DOI Listing

Formalin-preserved zooplankton are not reliable for historical reconstructions of methylmercury bioaccumulation.

Sci Total Environ 2020 May 30;738:139803. Epub 2020 May 30.

Department of Marine Sciences, University of Connecticut, 1080 Shennecossett Rd, Groton, CT 06340, United States; Billion Oyster Project, Governors Island, 10 South St., Slip 7, New York, NY 10004, United States.

Time-series measurements of methylmercury (MeHg) concentrations in short-lived planktic animals, such as copepods, could allow for an evaluation of mercury (Hg) inputs and transferability to organisms in marine environments. If reliable, MeHg measurements in formalin-preserved marine animals could offer insights into past environmental MeHg levels. In the present study, we examined whether the amount of MeHg changed over time in formalin-preserved copepods for two species, Acartia tonsa, and Temora longicornis. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139803DOI Listing

Corrigendum to "Interaction of central obesity and sarcopenia on nutritional status in the community-dwelling older people" [Archives of Gerontology and Geriatrics 87 (March-April) (2020) 104003].

Arch Gerontol Geriatr 2020 Jun 17:104153. Epub 2020 Jun 17.

Department of Family Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Gerontology, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.archger.2020.104153DOI Listing

Integrated biomarker parameters response to the toxic effects of high stocking density, CuSO, and trichlorfon on fish and protective role mediated by Angelica sinensis extract.

Fish Physiol Biochem 2020 Jun 15. Epub 2020 Jun 15.

College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, Sichuan, China.

The present study explored the protective role of dietary the extract of Angelica sinensis (EAs) on high density, CuSO, or trichlorfon-treated Crucian carp (Carassius auratus auratus). Firstly, the study showed that the optimum density for growth and growth inhibition was 0.49 and 0. Read More

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http://dx.doi.org/10.1007/s10695-020-00821-9DOI Listing

Epidemiology of lung cancer in northeast of Iran: A 25-year study of 939 patients.

Med J Islam Repub Iran 2020 7;34:17. Epub 2020 Mar 7.

Department of Community Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Lung cancer (LC) is a global public health priority. In this study, the epidemiology and current trends of primary LCs were investigated in northeast of Iran. Demographic and pathologic records of primary LCs during 1985-2012 in Mashhad (capital of northeast of Iran) were reviewed. Read More

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http://dx.doi.org/10.34171/mjiri.34.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293801PMC

Natural archives of long-range transported contamination at the remote lake Letšeng-la Letsie, Maloti Mountains, Lesotho.

Sci Total Environ 2020 May 25:139642. Epub 2020 May 25.

School of Geography, Archaeology and Environmental Studies, University of the Witwatersrand, 1 Jan Smuts Avenue, Braamfontein, 2050, South Africa; Department of Geography, Environmental Management and Energy Studies, University of Johannesburg, Corner Ditton and University Avenue, Auckland Park, Johannesburg, South Africa.

Naturally accumulating archives, such as lake sediments and wetland peats, in remote areas may be used to identify the scale and rates of atmospherically deposited pollutant inputs to natural ecosystems. Co-located lake sediment and wetland cores were collected from Letšeng-la Letsie, a remote lake in the Maloti Mountains of southern Lesotho. The cores were radiometrically dated and analysed for a suite of contaminants including trace metals and metalloids (Hg, Pb, Cu, Ni, Zn, As), fly-ash particles, stable nitrogen isotopes, polycyclic aromatic hydrocarbons (PAHs) and persistent organic pollutants such as polychlorinated biphenyls (PCBs), polybrominated flame retardants (PBDEs) and hexachlorobenzene (HCB). Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139642DOI Listing

Ecological regime shift preserved in the Anthropocene stratigraphic record.

Proc Biol Sci 2020 Jun 17;287(1929):20200695. Epub 2020 Jun 17.

Department of Palaeontology, University of Vienna, Althanstrasse 14, 1090 Vienna.

Palaeoecological data are unique historical archives that extend back far beyond the last several decades of ecological observations. However, the fossil record of continental shelves has been perceived as too coarse (with centennial-millennial resolution) and incomplete to detect processes occurring at yearly or decadal scales relevant to ecology and conservation. Here, we show that the youngest (Anthropocene) fossil record on the northern Adriatic continental shelf provides decadal-scale resolution that accurately documents an abrupt ecological change affecting benthic communities during the twentieth century. Read More

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http://dx.doi.org/10.1098/rspb.2020.0695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329033PMC

[Biobanking in Psychiatry].

Fortschr Neurol Psychiatr 2020 Jun 15. Epub 2020 Jun 15.

Medical biobanking is concerned with establishing and maintaining large-scale repositories of biological specimens combined with comprehensive archives of clinical and biographical information on donors. This aims for controlled high and consistent quality of specimens for future biomedical research. One major objective is to assemble multiple blood components for various types of biochemical analysis and experimentation including different isolated cell types. Read More

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http://dx.doi.org/10.1055/a-0832-8766DOI Listing

A Forgotten Tale from the Great War: General Lorenzo Bonomo and the Birth of Italian War Neurosurgery.

World Neurosurg 2020 Jun 12;140:338-346. Epub 2020 Jun 12.

Rome Army Hospital Celio, Neurosurgery Division, Roma, Italy.

Little is known of the advances in battlefield medicine achieved in Italy before and during the Great War. Some deserve wider recognition; this is especially true for the field of neurosurgery. There are a limited number of historical records currently available, fewer still in English, and most of the systematic investigations on field surgery have been in the form of monographs within science history reviews, which obviously lack a strictly clinical perspective. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.113DOI Listing

Innovative use of data sources: a cross-sectional study of data linkage and artificial intelligence practices across European countries.

Arch Public Health 2020 10;78:55. Epub 2020 Jun 10.

Department of Non-Communicable Diseases and Injuries, Santé Publique France, 12 rue du Val d'Osne, 94415 Saint-Maurice, France.

Background: The availability of data generated from different sources is increasing with the possibility to link these data sources with each other. However, linked administrative data can be complex to use and may require advanced expertise and skills in statistical analysis. The main objectives of this study were to describe the current use of data linkage at the individual level and artificial intelligence (AI) in routine public health activities, to identify the related estimated health indicators (i. Read More

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http://dx.doi.org/10.1186/s13690-020-00436-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288525PMC

Multiple sclerosis coverage in the written media of a low prevalence country.

Mult Scler Relat Disord 2020 Jun 11;44:102266. Epub 2020 Jun 11.

Multiple Sclerosis Center, Department of Neurology, Hospital Universitario Nacional de Colombia. Bogotá, Colombia; Grupo de Investigación en Neurología de la Universidad Nacional de Colombia - NEURONAL. Bogotá, Colombia.

Background: Awareness in the community is an important factor across a wide range of diseases and the communication media have an important role in its promotion. However, misinformation and misguide may take place heightening the expectations of people affected by chronic conditions such as multiple sclerosis (MS). This study explores media coverage of MS in a low prevalence country. Read More

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http://dx.doi.org/10.1016/j.msard.2020.102266DOI Listing

Prostate MRI radiomics: A systematic review and radiomic quality score assessment.

Eur J Radiol 2020 May 30;129:109095. Epub 2020 May 30.

Department of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.

Background: Radiomics have the potential to further increase the value of MRI in prostate cancer management. However, implementation in clinical practice is still far and concerns have been raised regarding the methodological quality of radiomic studies. Therefore, we aimed to systematically review the literature to assess the quality of prostate MRI radiomic studies using the radiomics quality score (RQS). Read More

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http://dx.doi.org/10.1016/j.ejrad.2020.109095DOI Listing

FARFAR2: Improved De Novo Rosetta Prediction of Complex Global RNA Folds.

Structure 2020 Jun 11. Epub 2020 Jun 11.

Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA; Biophysics Program, Stanford University, Stanford, CA 94305, USA. Electronic address:

Predicting RNA three-dimensional structures from sequence could accelerate understanding of the growing number of RNA molecules being discovered across biology. Rosetta's Fragment Assembly of RNA with Full-Atom Refinement (FARFAR) has shown promise in community-wide blind RNA-Puzzle trials, but lack of a systematic and automated benchmark has left unclear what limits FARFAR performance. Here, we benchmark FARFAR2, an algorithm integrating RNA-Puzzle-inspired innovations with updated fragment libraries and helix modeling. Read More

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http://dx.doi.org/10.1016/j.str.2020.05.011DOI Listing

Challenges in the Clinical and Radiological Differential Diagnosis of Cerebrovascular Events and Malignant Primary Brain Tumors: Reports from a Retrospective Case Series.

Turk Neurosurg 2020 May 20. Epub 2020 May 20.

University of Health Sciences, Gaziosmanpasa Training and Resarch Hospital, Department of Neurosurgery, Istanbul, Turkey.

Aim: To reveal difficulties in differential diagnosis of some cases of cerebrovascular events (CVE)) and malignant primary brain tumors (MBT) even a multidiciplinary evaluation in Grand rounds.

Material And Methods: This study retrospectively analyzed the patient archives from January 2017-January 2020. The records of 572 patients discussed in these meetings were examined. Read More

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http://dx.doi.org/10.5137/1019-5149.JTN.30371-20.2DOI Listing

Outcomes After Revision Anterior Shoulder Stabilization: A Systematic Review.

Orthop J Sports Med 2020 May 29;8(5):2325967120922571. Epub 2020 May 29.

Duke Sports Sciences Institute, Department of Orthopaedic Surgery, Duke University, Durham, North Carolina, USA.

Background: Primary shoulder stabilization is successful, but there continues to be a risk of recurrence after operative repair, particularly in the young athlete. It is important for surgeons to understand the outcomes after various revision stabilization techniques to best counsel patients and manage expectations.

Purpose: To analyze recurrent instability and revision surgery rates in patients who underwent revision anterior glenohumeral stabilization procedures with either arthroscopic repair, open repair, coracoid transfer, free bone block, or capsular reconstruction. Read More

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http://dx.doi.org/10.1177/2325967120922571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263126PMC

Gonadulins, the fourth type of insulin-related peptides in decapods.

Authors:
Jan A Veenstra

Gen Comp Endocrinol 2020 Jun 9;296:113528. Epub 2020 Jun 9.

INCIA UMR 5287 CNRS, University of Bordeaux, Pessac, France. Electronic address:

Insulin and related peptides play important roles in the regulation of growth and reproduction. Until recently three different types of insulin-related peptides had been identified from decapod crustaceans. The identification of two novel insulin-related peptides from Sagmariasus verreauxi and Cherax quadricarinatus suggested that there might a fourth type. Read More

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http://dx.doi.org/10.1016/j.ygcen.2020.113528DOI Listing

LMO2 Expression Distinguishes T-Lymphoblastic Leukemia/Lymphoma from Indolent T-Lymphoblastic Proliferations.

Histopathology 2020 Jun 11. Epub 2020 Jun 11.

Department of Pathology, University of California San Francisco, San Francisco, CA, 94143, USA.

Aims: An indolent T-lymphoblastic proliferation (iT-LBP) is a benign, reactive expansion of immature TdT+ T-cells found in extrathymic tissues. iT-LBP can be challenging to distinguish from malignant processes, specifically T-lymphoblastic lymphoma (T-LBL), given the overlapping clinical and histologic features. Recently, it has been shown that LIM domain only 2 (LMO2) is overexpressed in T-LBL but not in reactive immature TdT+ T-cells in the thymus. Read More

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http://dx.doi.org/10.1111/his.14176DOI Listing

"Fair to all interests and impartial towards all schools of thought": in honour of the 150th anniversary of the foundation of the "Archiv/Archives".

Arch Gynecol Obstet 2020 Jun 10. Epub 2020 Jun 10.

Practice for Women's Health, Gynecology and Obstetrics, Berlin, Germany.

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http://dx.doi.org/10.1007/s00404-020-05637-9DOI Listing

Expression of PKG2 in ovarian cancer and its effect on epidermal growth factor receptor.

J BUON 2020 Mar-Apr;25(2):729-735

Department of Obstetrics and Gynecology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, P.R. China.

Purpose: This research tried to explore the expression level of II cGMP-dependent protein kinase (PKG2) in human ovarian tissue and to clarify the molecular mechanism of EGFR regulation and its clinical significance.

Methods: The expression levels of PKG2 and EGFR in 10 normal ovarian tissues, 14 benign ovarian tumor tissues and 39 epithelial ovarian cancer tissues preserved in the archives of the Affiliated Hospital of Xuzhou Medical University from 2016 to 2018 were detected by real-time fluorescence quantitative (RT-PCR), and the correlation between the expressions of the two genes was analyzed. The expressions of in vitro cultured ovarian cancer cell lines SKOV3, PKG2 and EGFR were detected by RT-PCR and western blot, and the over-expressed PKG2 plasmid and PKG2 small interfering RNA (siRNA) were transfected into the cells, and the protein and phosphorylation of Akt and ERK in EGFR and its downstream signaling pathway were detected by western blot. Read More

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Could a mannequin simplify rhinopharyngeal swab collection in COVID 19 patients?

Eur Arch Otorhinolaryngol 2020 Jun 9. Epub 2020 Jun 9.

Otorhinolaryngology Unit, Ospedali Riuniti Padova Sud "Madre Teresa di Calcutta" Hub Covid Hospital Monselice (Padova) - ULSS, 6 Euganea, Padua, Italy.

Rhinopharyngeal swab collection is used to test patients for COVID-19; unfortunately, the false negative rate is around 30% in symptomatic patients, and maybe even higher in asymptomatic ones. A correct swab collection is consequently critical. Swabs are usually performed by dedicated personnel, but at the present moment, the methods for its training are not standardized. Read More

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http://dx.doi.org/10.1007/s00405-020-06113-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282467PMC

The origin and widespread occurrence of Sli-based self-compatibility in potato.

Theor Appl Genet 2020 Jun 8. Epub 2020 Jun 8.

Plant Breeding, Wageningen University, P.O. Box 386, 6700 AJ, Wageningen, The Netherlands.

Self-compatible (SC) diploid potatoes allow innovative potato breeding. Therefore, the Sli gene, originally described in S. chacoense, has received much attention. Read More

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http://dx.doi.org/10.1007/s00122-020-03627-8DOI Listing

Massive formation of early diagenetic dolomite in the Ediacaran ocean: Constraints on the "dolomite problem".

Proc Natl Acad Sci U S A 2020 Jun 8;117(25):14005-14014. Epub 2020 Jun 8.

Institute for Geology, Mineralogy, and Geophysics, Ruhr University Bochum, D-44801 Bochum, Germany.

Paleozoic and Precambrian sedimentary successions frequently contain massive dolomicrite [CaMg(CO)] units despite kinetic inhibitions to nucleation and precipitation of dolomite at Earth surface temperatures (<60 °C). This paradoxical observation is known as the "dolomite problem." Accordingly, the genesis of these dolostones is usually attributed to burial-hydrothermal dolomitization of primary limestones (CaCO) at temperatures of >100 °C, thus raising doubt about the validity of these deposits as archives of Earth surface environments. Read More

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http://dx.doi.org/10.1073/pnas.1916673117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321997PMC

Odontogenic keratocyst: Analysis of recurrence by AgNOR, p53 and MDM2 profiling.

J Oral Maxillofac Pathol 2020 Jan-Apr;24(1):184-185. Epub 2020 May 8.

Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, USA.

Background: Odontogenic keratocyst (OKC) is a clinical entity with characteristic microscopic features, high growth potential and propensity to recur. Aggressive behavior and higher tendency for recurrence have been attributed to greater proliferative activity of epithelial lining. The incidence of recurrence in various reported series ranges from 2. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_129_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269273PMC

Malocclusion: An adjunctive aid in individual identification.

J Oral Maxillofac Pathol 2020 Jan-Apr;24(1):138-142. Epub 2020 May 8.

Department of Orthodontics and Dentofacial Orthopaedics, Vokkaligara Sangha Dental College and Hospital, Bengaluru, Karnataka, India.

Introduction: Cheiloscopy and dactyloscopy have long been the most commonly used methods for forensic investigations. Orthodontists perform numerous diagnostic procedures, which include radiographs, photographs and impressions of the teeth and palate for the evaluation of malocclusion. The data recorded by them provide immense information about a patient. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_340_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269286PMC

Relative frequency of oral focal reactive overgrowths: An institutional retrospective study.

J Oral Maxillofac Pathol 2020 Jan-Apr;24(1):76-80. Epub 2020 May 8.

Department of Oral Pathology and Microbiology, Bareilly International University, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.

Context: Focal fibrous hyperplasia, peripheral ossifying fibroma, pyogenic granuloma, peripheral giant cell granuloma, giant cell fibroma and focal reactive overgrowth (FROGs) are one of the foremost numerous benign soft-tissue growths in the oral cavity. Chronic irritation or trauma is with identified as the causative aspect. It may develop up to few centimeters in diameter, pedunculated or sessile and may arise on the gingiva or buccal mucosa. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_350_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269285PMC

The origin and underlying driving forces of the SARS-CoV-2 outbreak.

J Biomed Sci 2020 Jun 7;27(1):73. Epub 2020 Jun 7.

Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.

Background: SARS-CoV-2 began spreading in December 2019 and has since become a pandemic that has impacted many aspects of human society. Several issues concerning the origin, time of introduction to humans, evolutionary patterns, and underlying force driving the SARS-CoV-2 outbreak remain unclear.

Method: Genetic variation in 137 SARS-CoV-2 genomes and related coronaviruses as of 2/23/2020 was analyzed. Read More

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http://dx.doi.org/10.1186/s12929-020-00665-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276232PMC

Odontogenic Myxoma: A 23-Year Retrospective Series of 38 Cases.

Head Neck Pathol 2020 Jun 6. Epub 2020 Jun 6.

Division of Oral and Maxillofacial Pathology, University of Florida College of Dentistry, 1395 Center Dr, Gainesville, FL, 32610-0414, USA.

Odontogenic myxoma (OM) is an uncommon benign odontogenic tumor arising in the jaw. Though it has slight histologic overlap with other entities, definitive diagnosis is imperative considering the tumor's aggressive nature, high recurrence rate, and necessity of radical surgical intervention in large-sized lesions. With IRB approval, a retrospective search of the University of Florida College of Dentistry Oral Pathology Biopsy Service archives from 1994 to 2017 for diagnosis of OM of the jaw was performed. Read More

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http://dx.doi.org/10.1007/s12105-020-01191-7DOI Listing

Evidence for the use of triage, respiratory isolation, and effective treatment to reduce the transmission of Mycobacterium tuberculosis in health care settings: a systematic review.

Clin Infect Dis 2020 Jun 5. Epub 2020 Jun 5.

TB Centre, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Evidence is limited for infection prevention and control (IPC) measures reducing Mycobacterium tuberculosis (MTB) transmission in health facilities. This systematic review, one of seven commissioned by the World Health Organization to inform the 2019 update of global tuberculosis (TB) IPC guidelines, asked: do triage and/or isolation and/or effective treatment of TB disease reduce MTB transmission in health care settings? Of 25 included articles, 19 reported latent TB infection (LTBI) incidence in health care workers (HCWs; absolute risk reductions 1%-21%); five reported TB disease incidence in HCWs (no/slight [high TB burden] or moderate [low burden] reduction) and two in HIV-positive in-patients (6%-29% reduction). 23/25 studies implemented multiple IPC measures; effects of individual measures could not be disaggregated. Read More

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http://dx.doi.org/10.1093/cid/ciaa720DOI Listing

Shuttered natural history museums fight for survival.

Science 2020 06;368(6495):1042-1043

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http://dx.doi.org/10.1126/science.368.6495.1042DOI Listing

Health Help-Seeking Behaviour in Spiritual Healing Practice: Records from the Panacea Society's Healing Department, 1924-1997.

J Relig Health 2020 Jun 3. Epub 2020 Jun 3.

Faculty of Divinity, University of Cambridge, West Road, Cambridge, CB3 9BS, UK.

Why people seek help is a question shared by both health psychologists and scholars of spiritual healing. This overlap, however, has gone unexplored. This article shows convergence between health help-seeking behaviours in spiritual healing and secular professional health services. Read More

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http://dx.doi.org/10.1007/s10943-020-01044-1DOI Listing