3,724 results match your criteria Archives Of Disease In Childhood-fetal And Neonatal Edition[Journal]


Bowel loop sign in a newborn.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 6. Epub 2020 Jul 6.

Pediatric General Surgery, Ospedale Infantile Regina Margherita, Turin, Italy.

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http://dx.doi.org/10.1136/archdischild-2020-318939DOI Listing

Cutis marmorata telangiectatica congenita.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 6. Epub 2020 Jul 6.

Paediatrics, Stoke Mandeville Hospital, Aylesbury, Buckinghamshire, UK.

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http://dx.doi.org/10.1136/archdischild-2020-319612DOI Listing

Drainage, irrigation and fibrinolytic therapy (DRIFT) for posthaemorrhagic ventricular dilatation: 10-year follow-up of a randomised controlled trial.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 4. Epub 2020 Jul 4.

Neonatal Neurology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK.

Background: Progressive ventricular dilatation after intraventricular haemorrhage (IVH) in preterm infants has a very high risk of severe disability and death. Drainage, irrigation and fibrinolytic therapy (DRIFT), in a randomised controlled trial (RCT), reduced severe cognitive impairment at 2 years.

Objective: To assess if the cognitive advantage of DRIFT seen at 2 years persisted until school age. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318231DOI Listing

Provider visual attention on a respiratory function monitor during neonatal resuscitation.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 2. Epub 2020 Jul 2.

Department of Pediatrics, Division of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Background: A respiratory function monitor (RFM) provides real-time positive pressure ventilation feedback. Whether providers use RFM during neonatal resuscitation is unknown.

Methods: Ancillary study to the MONITOR(NCT03256578) randomised controlled trial. Read More

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http://dx.doi.org/10.1136/archdischild-2020-319291DOI Listing

Outcomes of haemoglobin Bart's hydrops fetalis following intrauterine transfusion in Ontaria, Canada.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 2. Epub 2020 Jul 2.

Department of Paediatric Haematology/Oncology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Objectives: With improved access to intrauterine transfusion (IUT), more fetuses with haemoglobin Bart's hydrops fetalis (HBHF; homozygous α-thalassaemia) will survive.

Design: To evaluate the long-term outcomes of affected fetuses with and without IUT in Ontario, Canada, we retrospectively collected data on IUTs and pregnancy outcomes in all cases of HBHF, from 1989 to 2014. Clinical outcome and neurocognitive profiles of long-term survivors were also collected and compared with data from 24 patients with transfusion-dependent β-thalassaemia (TDT-β). Read More

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http://dx.doi.org/10.1136/archdischild-2019-317626DOI Listing

Effect of opaque wraps for pulse oximeter sensors: randomised cross-over trial.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 1. Epub 2020 Jul 1.

Neonatal Intensive Care Unit, University Hospital of North Tees, Stockton on Tees, United Kingdom.

Background: Evidence is lacking as to whether ambient light or phototherapy light could interfere with pulse oximeter performance.

Methods: In this randomised cross-over trial, we recruited neonates of gestation >24 weeks. Consented infants were randomly assigned to either pulse oximeter sensor with opaque wrap or without opaque wrap. Read More

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http://dx.doi.org/10.1136/archdischild-2020-319049DOI Listing

Incidence of SARS-CoV-2 vertical transmission: a meta-analysis.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 25. Epub 2020 Jun 25.

Neonatology, Khoo Teck-Puat- National University Children's Medical Institute, National University Health System, Singapore

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http://dx.doi.org/10.1136/archdischild-2020-319791DOI Listing

Scrotoschisis: an extremely rare congenital anomaly.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 22. Epub 2020 Jun 22.

Department of Paediatric Surgery, Great North Children's Hospital, Newcastle Upon Tyne, UK.

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http://dx.doi.org/10.1136/archdischild-2020-319345DOI Listing

Nasal insertion depths for neonatal intubation.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 22. Epub 2020 Jun 22.

Department of Neonatology, University Children's Hospital Tubingen, Tubingen, Germany.

Aim: Data on the depth of nasal intubation in neonates are rare, although this is the preferred route in some countries. Therefore, recommendations on optimal nasal intubation depths based on gestational age (GA) and weight are desirable.

Methods: We determined the distances between the middle of thoracic vertebrae 2 (T2) and the tip of the endotracheal tube in 116 X-rays from nasally intubated neonates. Read More

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http://dx.doi.org/10.1136/archdischild-2020-319140DOI Listing

Experience and training in endotracheal intubation and laryngeal mask airway use in neonates: results of a national survey.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 22. Epub 2020 Jun 22.

Newborn Services, John Radcliffe Hospital, Oxford, Oxfordshire, UK.

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http://dx.doi.org/10.1136/archdischild-2020-319118DOI Listing

Fate of pulmonary hypertension associated with bronchopulmonary dysplasia beyond 36 weeks postmenstrual age.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 22. Epub 2020 Jun 22.

Pediatric and Congenital Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.

Objective: To determine the survival and evolution of pulmonary hypertension (PH) associated with bronchopulmonary dysplasia (BPD) in extremely premature born infants beyond 36 weeks postmenstrual age (PMA).

Design: A single-centre retrospective cohort study from a university hospital.

Patients: Extremely preterm (gestational age <30 weeks and/or birth weight <1000 g) infants, born between 2012 and 2017, in the University Medical Center Groningen with confirmed PH at/beyond 36 weeks PMA. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318531DOI Listing

Outcomes of endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid: a systematic review and meta-analysis.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 19. Epub 2020 Jun 19.

Faculty of Medicine and Public Health, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, Thailand.

Objective: We aimed to systematically review and analyse the outcomes of non-endotracheal suctioning (non-ETS) versus ETS in non-vigorous meconium-stained neonates.

Design: We conducted a systematic review of non-ETS and ETS in non-vigorous infants born through meconium-stained amniotic fluid (MSAF). We searched PubMed/Medline, Scopus, Clinical Trials. Read More

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http://dx.doi.org/10.1136/archdischild-2020-318941DOI Listing
June 2020
3.120 Impact Factor

Does parental presence affect workload during neonatal resuscitation?

Arch Dis Child Fetal Neonatal Ed 2020 Jun 19. Epub 2020 Jun 19.

Neonatology, University of Alberta, Edmonton, Alberta, Canada

Background: Parents often prefer being present during neonatal resuscitation and benefit from this experience. We aim to determine if parental presence during neonatal resuscitation affects the perceived workload of healthcare providers.

Methods: Perceived workload was measured using the multidimensional retrospective National Aeronautics and Space Administration Task Load Index survey. Read More

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http://dx.doi.org/10.1136/archdischild-2020-318840DOI Listing

Reference values for the external genitalia of full-term and pre-term female neonates.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 19. Epub 2020 Jun 19.

Service d'endocrinologie pédiatrique, Hospices Civils de Lyon, Lyon, France.

Background And Objectives: Identifying virilisation of the genitalia in female newborns early during the neonatal period is important to diagnose pathologies. However, there is no clear threshold for clitoromegaly or for the anogenital ratio. The objective of this study was to define reference values for the external genitalia of full-term and pre-term female neonates. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318090DOI Listing

T-piece resuscitators: can they provide safe ventilation in a low compliant newborn lung?

Arch Dis Child Fetal Neonatal Ed 2020 Jun 16. Epub 2020 Jun 16.

Neonatal Intensive Care Unit, Westmead Hospital, Westmead, New South Wales, Australia.

Background: T-piece resuscitators (TPRs) are used for primary newborn resuscitation in birthing and emergency rooms worldwide. A recent study has shown spikes in peak inflation pressure (PIP) over set values with two brands of TPRs inbuilt into infant warmer/resuscitation platforms. We aimed to compare delivered ventilation between two TPR drivers with inflation pressure spikes to a standard handheld TPR in a low test lung compliance (Crs), leak-free bench test model. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318673DOI Listing

Transthoracic colour-encoded M-mode echocardiography demonstrating neonatal atrial flutter.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 16. Epub 2020 Jun 16.

Department of Paediatric Subspecialities, KK Women's and Children's Hospital, Singapore

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http://dx.doi.org/10.1136/archdischild-2020-319072DOI Listing

Bilateral fetal ovarian autoamputation.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 16. Epub 2020 Jun 16.

Department of Neonatal surgery, Guangdong Women and Children Hospital, Guangzhou, China

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http://dx.doi.org/10.1136/archdischild-2020-318902DOI Listing

National active surveillance to understand and inform neonatal care in COVID-19.

Arch Dis Child Fetal Neonatal Ed 2020 07 14;105(4):346-347. Epub 2020 Jun 14.

NIHR Policy Research Unit in Maternal and Neonatal Health and Care, National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/archdischild-2020-319372DOI Listing

PHACE syndrome: importance of distinguishing infantile haemangioma from capillary malformation.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 10. Epub 2020 Jun 10.

Department of Dermatology, Galway University Hospital, Galway, Ireland.

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http://dx.doi.org/10.1136/archdischild-2020-318923DOI Listing

Parent experience of caring for neonates with seizures.

Arch Dis Child Fetal Neonatal Ed 2020 Jun 5. Epub 2020 Jun 5.

Family Health Care Nursing, University of California San Francisco School of Nursing, San Francisco, California, USA.

Objective: Neonates with seizures have a high risk of mortality and neurological morbidity. We aimed to describe the experience of parents caring for neonates with seizures.

Design: This prospective, observational and multicentre () study enrolled parents of neonates with acute symptomatic seizures. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318612DOI Listing

Case of cutaneous infection in an extremely preterm infant.

Arch Dis Child Fetal Neonatal Ed 2020 May 28. Epub 2020 May 28.

Southmead Neonatal Unit, North Bristol NHS Trust, Westbury on Trym, UK.

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http://dx.doi.org/10.1136/archdischild-2020-318894DOI Listing

Diffuse excessive high signal intensity on term equivalent MRI does not predict disability: a systematic review and meta-analysis.

Arch Dis Child Fetal Neonatal Ed 2020 May 25. Epub 2020 May 25.

Neonatal Intensive Care Unit, King Edward Memorial Hospital for Women Perth, Subiaco, Western Australia, Australia.

Objective: To evaluate whether diffuse excessive high signal intensity (DEHSI) on term equivalent age MRI (TEA-MRI) predicts disability in preterm infants.

Design: This is a systematic review and meta-analysis. Medline, EMBASE, Cochrane Library, EMCARE, Google Scholar and MedNar databases were searched in July 2019. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318207DOI Listing

Neonatal outcomes of extremely preterm twins by sex pairing: an international cohort study.

Arch Dis Child Fetal Neonatal Ed 2020 May 25. Epub 2020 May 25.

Department of Pediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada.

Objective: Infant boys have worse outcomes than girls. In twins, the 'male disadvantage' has been reported to extend to female co-twins via a 'masculinising' effect. We studied the association between sex pairing and neonatal outcomes in extremely preterm twins. Read More

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http://dx.doi.org/10.1136/archdischild-2020-318832DOI Listing
May 2020
3.120 Impact Factor

Generating longitudinal growth charts from preterm infants fed to current recommendations.

Arch Dis Child Fetal Neonatal Ed 2020 May 25. Epub 2020 May 25.

Department of Neonatal Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Objective: To use repeated measurements of weight, length and head circumference to generate growth centile charts reflecting real-world growth of a population of very preterm infants with a well-described nutritional intake close to current recommendations.

Design: Infants born before 30 weeks gestational age (GA) were recruited. Infants received nutrition according to an integrated care pathway, with nutrient intake recorded daily, weight recorded twice-weekly and length and head circumference weekly. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318404DOI Listing

Neonatal intubation success rates: four UK units.

Arch Dis Child Fetal Neonatal Ed 2020 May 15. Epub 2020 May 15.

Neonatology, Royal Hospital for Children Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1136/archdischild-2020-319111DOI Listing

Resuscitation outcomes for weekend deliveries of very low birthweight infants.

Arch Dis Child Fetal Neonatal Ed 2020 May 15. Epub 2020 May 15.

Department of Obstetrics & Gynecology/Public Health & Preventive Medicine, Oregon Health & Science University, Portland, Oregon, USA.

Objective: To characterise the association between weekend (Saturday and Sunday) deliveries of very low birthweight (VLBW) infants and delivery room outcomes in the 'golden hour' after birth.

Design And Setting: A retrospective cohort study using California Perinatal Quality Care Collaborative data from participating neonatal intensive care units.

Patients: The study population after exclusions was 26 515 VLBW infants born in California from 2010 to 2016. Read More

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http://dx.doi.org/10.1136/archdischild-2019-317807DOI Listing

Treatment of infants with craniofacial malformations.

Arch Dis Child Fetal Neonatal Ed 2020 May 14. Epub 2020 May 14.

Interdisciplinary Centre for Cleft Palate and Craniofacial Malformations, Tuebingen University Hospital, Tuebingen, Germany

Infants with craniofacial malformations (CFMs) are at increased risk of various clinical problems, including respiratory and feeding disorders, the result of which may be long-lasting. An improvement in clinical care can be achieved by prenatal diagnosis and interdisciplinary birth preparation. Feeding problems may particularly be stressful for the family and require a team approach involving nursing staff, speech therapists and nutritional specialists to anticipate, avoid and treat sequelae such as failure to thrive or recurrent aspirations. Read More

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http://dx.doi.org/10.1136/archdischild-2019-317890DOI Listing

Implementation of bowel ultrasound practice for the diagnosis and management of necrotising enterocolitis.

Arch Dis Child Fetal Neonatal Ed 2020 May 12. Epub 2020 May 12.

Neonatal Service, Poole Hospital NHS Foundation Trust, Poole, UK

Necrotising enterocolitis (NEC) is a serious inflammatory bowel disease of prematurity with potentially devastating complications and remains a leading cause of morbidity and mortality among premature infants. In recent years, there has been accumulating data regarding benefits of using bowel ultrasound (BUS) in the diagnosis and management of NEC. Despite this, adoption of robust BUS programmes into clinical practice has been slow. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318382DOI Listing

Developmental trajectories of infants born at less than 30 weeks' gestation on the Bayley-III Scales.

Arch Dis Child Fetal Neonatal Ed 2020 May 3. Epub 2020 May 3.

Department of Women's Health, University College London Hospitals NHS Foundation Trust, London, UK

Objective: To describe the cognitive, language and motor developmental trajectories of children born very preterm and to identify perinatal factors that predict the trajectories.

Design: Data from a cohort of 1142 infants born at <30 weeks' gestation who were prospectively assessed on the Bayley Scales of Infant and Toddler Development, third edition (Bayley-III) at 3, 6, 12 and 24 months corrected age, were analysed using the Super Imposition by Translation and Rotation (SITAR) growth curve analysis model.

Main Outcome Measures: Developmental trajectory SITAR models for Bayley-III cognitive, language (receptive and expressive communication subscales) and motor (fine and gross motor subscales) scores. Read More

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http://dx.doi.org/10.1136/archdischild-2019-317810DOI Listing

Congenital onset of neonatal lupus erythematosus.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 3;105(4):356. Epub 2020 May 3.

Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Emilia-Romagna, Italy.

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http://dx.doi.org/10.1136/archdischild-2020-319172DOI Listing

Quality improvement programme to increase the rate of deferred cord clamping at preterm birth using the Lifestart trolley.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 29. Epub 2020 Apr 29.

Neonatal Unit, Liverpool Women's Hospital NHS Foundation Trust, Liverpool, UK

Aim: To increase the documented use of the Lifestart trolley to allow premature infants' (<32 weeks' gestation) resuscitation and stabilisation with an intact umbilical cord at delivery.

Design: A 13-month quality improvement programme from April 2018 to April 2019 was undertaken using Plan, Do, Study and Act (PDSA) cycles. Data were reviewed from 113 consecutive preterm (<32 weeks) deliveries to identify whether Lifestart was used and whether 2 min deferred cord clamping (DCC) occurred in eligible infants as per hospital policy. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318636DOI Listing

Reflexes that impact spontaneous breathing of preterm infants at birth: a narrative review.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 29. Epub 2020 Apr 29.

Neonatology, Leiden University Medical Center, Leiden, The Netherlands.

Some neural circuits within infants are not fully developed at birth, especially in preterm infants. Therefore, it is unclear whether reflexes that affect breathing may or may not be activated during the neonatal stabilisation at birth. Both sensory reflexes (eg, tactile stimulation) and non-invasive ventilation (NIV) can promote spontaneous breathing at birth, but the application of NIV can also compromise breathing by inducing facial reflexes that inhibit spontaneous breathing. Read More

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http://dx.doi.org/10.1136/archdischild-2020-318915DOI Listing

Sprinkled water drops on the skin in newborns: congenital miliaria crystallina.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 20. Epub 2020 Apr 20.

Neonatology, Health Sicences University, Izmir Tepecik Training and Research Hospital, Izmir, Turkey.

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http://dx.doi.org/10.1136/archdischild-2020-319008DOI Listing

How does the impact delivery of Newborn Life Support? A Resuscitation Council UK response.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 9. Epub 2020 Apr 9.

Resuscitation Council (UK), London, UK.

In October 2019, the British Association of Perinatal Medicine (BAPM) published a Framework1 and associated infographic2 for ' This outlined an approach, based on data from the UK and abroad, to assist clinicians in decision-making relating to perinatal care at ≤26 weeks gestation. Many frontline providers of delivery room care of extremely preterm infants will have completed a Resuscitation Council UK (RCUK) Newborn Life Support or Advanced Resuscitation of the Newborn Infant course. This RCUK response to the BAPM Framework highlights how this might impact on their approach. Read More

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http://dx.doi.org/10.1136/archdischild-2020-318927DOI Listing
April 2020
3.120 Impact Factor

Sternal cleft in a newborn.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 8. Epub 2020 Apr 8.

Department of Pediatric Orthopaedic Surgery, University Hospital of Amiens-Picardie, Amiens, France.

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http://dx.doi.org/10.1136/archdischild-2020-319104DOI Listing

Continuous neurally adjusted ventilation: a feasibility study in preterm infants.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 8. Epub 2020 Apr 8.

Department of Pediatrics, CHU Sainte-Justine, Montreal, Quebec, Canada

Objectives: To assess the feasibility and tolerance of NeuroPAP, a new non-invasive ventilation mode which continuously adjusts (during both inspiration and expiration) the pressure support proportionally to the diaphragm electrical activity (Edi), in preterm infants and to evaluate the impact on ventilation pressure and Edi.

Design: Prospective cross-over single-centre feasibility study.

Setting: One level 3 neonatal intensive care unit in Canada. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318660DOI Listing
April 2020
3.120 Impact Factor

Blue LED phototherapy in preterm infants: effects on an oxidative marker of DNA damage.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 8. Epub 2020 Apr 8.

Department of Neonatology, Beatrix Children's Hospital, University Medical Centre Groningen, Groningen, The Netherlands.

Background: Phototherapy is used on the majority of preterm infants with unconjugated hyperbilirubinaemia. The use of fluorescent tube phototherapy is known to induce oxidative DNA damage in infants and has largely been replaced by blue light-emitting diode phototherapy (BLP). To date, it is unknown whether BLP also induces oxidative DNA damage in preterm infants. Read More

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http://dx.doi.org/10.1136/archdischild-2019-317024DOI Listing

Breast feeding at the time of COVID-19: do not forget expressed mother's milk, please.

Authors:
Riccardo Davanzo

Arch Dis Child Fetal Neonatal Ed 2020 07 6;105(4):455. Epub 2020 Apr 6.

Research Direction, Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, TS 34137, Italy

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http://dx.doi.org/10.1136/archdischild-2020-319149DOI Listing

Cell therapy for the preterm infant: promise and practicalities.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 6. Epub 2020 Apr 6.

Newborn Research Centre, Royal Women's Hospital, Parkville, Victoria, Australia.

Recent decades have seen the rapid progress of neonatal intensive care, and the survival rates of the most preterm infants are improving. This improvement is associated with changing patterns of morbidity and new phenotypes of bronchopulmonary dysplasia and preterm brain injury are recognised. Inflammation and immaturity are known contributors to their pathogenesis. Read More

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http://dx.doi.org/10.1136/archdischild-2019-317896DOI Listing

Routine use of videolaryngoscopy in neonatal unit.

Arch Dis Child Fetal Neonatal Ed 2020 Apr 6. Epub 2020 Apr 6.

NICU, Ashford and St Peter's Hospitals NHS Trust, Chertsey, UK

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http://dx.doi.org/10.1136/archdischild-2019-318470DOI Listing

Economic evaluation alongside the Speed of Increasing milk Feeds Trial (SIFT).

Arch Dis Child Fetal Neonatal Ed 2020 Apr 2. Epub 2020 Apr 2.

Health Economics Unit, Institute of Applied Health Research, University of Birmingham, Birmingham, UK

Objective: To evaluate the cost-effectiveness of two rates of enteral feed advancement (18 vs 30 mL/kg/day) in very preterm and very low birth weight infants.

Design: Within-trial economic evaluation alongside a multicentre, two-arm parallel group, randomised controlled trial (Speed of Increasing milk Feeds Trial).

Setting: 55 UK neonatal units from May 2013 to June 2015. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318346DOI Listing

Communicating bronchopulmonary foregut malformation 1a: imaging and approach.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 27;105(4):444. Epub 2020 Mar 27.

The Manchester Centre for Neonatal Surgery, Manchester University NHS Foundation Trust, Manchester, Greater Manchester, UK

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http://dx.doi.org/10.1136/archdischild-2019-318681DOI Listing

The practice of blood volume submitted for culture in a neonatal intensive care unit.

Arch Dis Child Fetal Neonatal Ed 2020 Mar 20. Epub 2020 Mar 20.

NSW NETS, Bankstown Aerodrome, New South Wales, Australia.

Background: Neonatal sepsis is the leading cause of mortality and morbidity in neonatal intensive care units. The volume of blood taken for culture remains one of the most important factors in isolating microorganisms.

Objectives: To evaluate the impact of the intervention on the blood volume submitted for culture and to identify factors influencing the volume as determined by the phlebotomist. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318080DOI Listing

Randomised trial of azithromycin to eradicate in preterm infants.

Arch Dis Child Fetal Neonatal Ed 2020 Mar 13. Epub 2020 Mar 13.

University of Maryland School of Pharmacy, Baltimore, Maryland, USA.

Objective: To test whether azithromycin eradicates from the respiratory tract in preterm infants.

Design: Prospective, phase IIb randomised, double-blind, placebo-controlled trial.

Setting: Seven level III-IV US, academic, neonatal intensive care units (NICUs). Read More

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http://dx.doi.org/10.1136/archdischild-2019-318122DOI Listing

Comparison of the management recommendations of the Kaiser Permanente neonatal early-onset sepsis risk calculator (SRC) with NICE guideline CG149 in infants ≥34 weeks' gestation who developed early-onset sepsis.

Arch Dis Child Fetal Neonatal Ed 2020 Mar 13. Epub 2020 Mar 13.

Neonatal Intensive Care, Singleton Hospital, Swansea, Wales, UK.

Objective: To compare the management recommendations of the Kaiser Permanente neonatal early-onset sepsis risk calculator (SRC) with National Institute for Health and Care Excellence (NICE) guideline CG149 in infants ≥34 weeks' gestation who developed early-onset sepsis (EOS).

Design: Retrospective multicentre study.

Setting: Five maternity services in South West of England and Wales. Read More

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http://dx.doi.org/10.1136/archdischild-2019-317165DOI Listing

Duct-dependent congenital heart disease in very preterm infants.

Arch Dis Child Fetal Neonatal Ed 2020 Mar 13. Epub 2020 Mar 13.

Department of Newborn Research, The Royal Women's Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1136/archdischild-2019-317742DOI Listing

Low risk of necrotising enterocolitis in enterally fed neonates with critical heart disease: an observational study.

Arch Dis Child Fetal Neonatal Ed 2020 Mar 13. Epub 2020 Mar 13.

Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, Goteborg, Sweden

Objective: We aimed to investigate the frequency of necrotising enterocolitis (NEC) in infants with critical congenital heart disease (CCHD) hypothesising that preoperative enteral feeding does not increase the risk of NEC.

Background: When NEC affects term infants, underlying risk factors such as asphyxia, sepsis or CCHD are often found. Due to fear of NEC development in infants with CCHD great caution is practised in many countries to defer preoperative enteral feeding, but in Sweden this is routinely provided. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318537DOI Listing

Perinatal stabilisation of infants born with congenital diaphragmatic hernia: a review of current concepts.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 13;105(4):449-454. Epub 2020 Mar 13.

The Ritchie Centre, Hudson Institute for Medical Research, Monash University, Melbourne, Victoria, Australia

Congenital diaphragmatic hernia (CDH) is associated with high mortality rates and significant pulmonary morbidity, mainly due to disrupted lung development related to herniation of abdominal organs into the chest. Pulmonary hypertension is a major contributor to both mortality and morbidity, however, treatment modalities are limited. Novel prenatal and postnatal interventions, such as fetal surgery and medical treatments, are currently under investigation. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318606DOI Listing

A time for hope: guidelines for the perinatal management of extremely preterm birth.

Arch Dis Child Fetal Neonatal Ed 2020 May 10;105(3):230-231. Epub 2020 Mar 10.

Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1136/archdischild-2019-318553DOI Listing

Umbilical cord milking in preterm infants: a systematic review and meta-analysis.

Arch Dis Child Fetal Neonatal Ed 2020 Mar 9. Epub 2020 Mar 9.

Department of Neonatology, Surya Hospitals, Mumbai, Maharashtra, India.

Objective: To conduct a systematic review and meta-analysis of the efficacy and safety of umbilical cord milking in preterm infants.

Design: Randomised controlled trials comparing umbilical cord milking with delayed cord clamping/immediate cord clamping in preterm infants were identified by searching databases, clinical trial registries and reference list of relevant studies in November 2019. Fixed effects model was used to pool the data on various clinically relevant outcomes. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318627DOI Listing