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    97 results match your criteria Arab journal of nephrology and transplantation[Journal]

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    Prevalence of seroconversion of hepatitis C virus among hemodialysis patients in Menoufia Governorate, Egypt.
    Arab J Nephrol Transplant 2014 May;7(2):133-5
    Internal Medicine Department, Nephrology Unit, Faculty of Medicine, Menofia University, Egypt.
    Introduction: Hepatitis C virus (HCV) is one of the most common infections among hemodialysis (HD) patients. It continues to be exasperating problem in many HD centers, in spite of strictly following infection and quality control measures.

    Methods: This is a multi-center retrospective comparative study, carried out in different HD units of Menoufia Governorate, Egypt. Read More

    Social aspects of kidney donation in Tunisia: a study of 189 living related donors.
    Arab J Nephrol Transplant 2014 May;7(2):129-31
    Department of Urology, Charles Nicolle Hospital of Tunis, Tunisia.
    Introduction: Our aim was to study the demographic and social characteristics of 189 living related kidney donors in Tunisia, and explore some of the social consequences of kidney donation.

    Methods: This is a descriptive retrospective study of 189 living related kidney donors who had their nephrectomy in Charles Nicolle Hospital between 1986 and 2009. The demographic and social characteristics at the time of donation were studied and changes in the social and occupational status after donation were assessed. Read More

    Clinical presentation and management outcome of childhood-onset systemic lupus erythamatosus in Baghdad.
    Arab J Nephrol Transplant 2014 May;7(2):125-7
    Pediatric Nephrologist; Medical City, Baghdad, Iraq.
    Introduction: Systemic lupus erythematosus (SLE) is an unpredictable autoimmune systemic disorder that often involves the kidney. In this study, we aimed to assess the clinical characteristics, pathological findings, and therapeutic response of children presenting with lupus nephritis (LN).

    Methods: We retrospectively studied 50 children with SLE admitted to the pediatric nephrology departments of four teaching hospitals in Baghdad between December 2009 and December 2011. Read More

    The clinical pattern of primary hyperoxaluria in pediatric patient at Queen Rania Abdulla Children Hospital.
    Arab J Nephrol Transplant 2014 May;7(2):119-23
    Pediatric Nephrology Unit, Queen Rania Abdulla Children Hospital, Jordan.
    Introduction: Hyperoxaluria is a metabolic disorder that can lead to end stage renal disease (ESRD). It can be either inherited or acquired. Primary hyperoxaluria (PHO) is more common and characterized by an excessive production of oxalate leading to recurrent urolithiasis and progressive nephrocalcinosis. Read More

    Re-examination of renal allograft biopsy blocks for C4d positivity: missed cases of antibody mediated rejection.
    Arab J Nephrol Transplant 2014 May;7(2):113-7
    Institute of Endemic diseases, Khartoum University, Khartoum, Sudan.
    Introduction: C4d immunostaining of renal allograft biopsies is recommended for the diagnosis of antibody-mediated rejection (ABMR), but it was not available to us prior to June 2012. In June 2012, we were able to obtain anti-human C4d polyclonal antibody and decided to retrospectively evaluate archived kidney allograft biopsies at our center for C4d deposition.

    Methods: Twenty-four paraffin blocks were available for this study. Read More

    Emphysematous pyelonephritis in a diabetic patient on maintenance hemodialysis: a case report.
    Arab J Nephrol Transplant 2014 May;7(2):109-11
    Departement of Nephrology, Fattouma Bourguiba Hospital and University Faculty of Medicine, Monastir, Tunisia.
    Introduction: Emphysematous pyelonephritis (EP) is an uncommon acute infection characterized by the presence of gas in the renal parenchyma. It is extremely rare in hemodialysis (HD) patients and diabetics account for most cases. It is a rapidly progressive and life threatening infection with a high mortality rate. Read More

    Prognosis of acute post-streptococcal glomerulonephritis in Sudanese children.
    Arab J Nephrol Transplant 2014 May;7(2):103-7
    Department of Pediatrics and Child Health, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
    Introduction: Acute post streptococcal glomerulo-nephritis (APSGN) is a form of acute nephritic syndrome characterized by edema, hematuria, proteinuria, and hypertension. The immediate prognosis of acute post-streptococcal glomerulonephritis in children is usually excellent, however, the long-term prognosis has been a subject of debate.

    Methods: This is a retrospective and prospective cohort study of Sudanese children with APSGN followed in a tertiary care hospital between 2006 and 2010. Read More

    The diagnostic value of detection of CD20 positive infiltrates in renal biopsies with acute allograft rejection: a pilot study.
    Arab J Nephrol Transplant 2014 May;7(2):97-101
    Internal Medicine Department, Cairo University, Cairo, Egypt.
    Introduction: The recognition of antibody mediated rejection has led to re-appreciation of the role of B cells in acute and chronic allograft rejection. The presence of CD20 positive lymphocytic infiltrates in acute cellular rejection has been associated with poor clinical outcomes and reduced graft survival. Recently molecular gene analysis has shown that grafts with antibody-mediated rejection (ABMR) have lower expression of CD20. Read More

    Uremic pruritus pathogenesis, revisited.
    Arab J Nephrol Transplant 2014 May;7(2):91-6
    Department of Nephrology, Internal Medicine, Zagazig University Hospital, Zagazig, Egypt.
    Introduction: Uremia is the most important systemic cause of pruritus. Uremic pruritus (UP) was found to affect 50-90% of patients undergoing dialysis and about 25% of patients with chronic kidney disease (CKD). Despite its high prevalence, morbidity and the marked influence on quality of life, UP remains poorly characterized. Read More

    Cardiovascular manifestations of allograft dysfunction in renal transplant recipients: a review.
    Arab J Nephrol Transplant 2014 May;7(2):83-9
    Dr. Taheri Medical Research Group, Tehran, Iran.
    Introduction: Cardiovascular complications are the leading cause of death among renal transplant recipients; renal graft dysfunction has special effects on cardiovascular morbidity and mortality.

    Review: Several studies have demonstrated a significant correlation between creatinine level and major coronary events, congestive heart failure and cerebrovascular events. Cardiovascular mortality has been related in different reports to serum creatinine levels and duration on renal replacement therapy. Read More

    Pattern of Renal Diseases among Children in The Niger Delta Region, Nigeria.
    Arab J Nephrol Transplant 2014 Jan;7(1):49-50
    Department of Pediatrics, University Teaching Hospital, Oghara, Delta State, Nigeria.
    Introduction: Childhood renal diseases are increasing in Nigeria. It is necessary to monitor the nature of these diseases in each locality for effective health care planning. Our aim was to document the nature of renal diseases in the Niger Delta Region of Nigeria and compare it with other regions in the country. Read More

    Prevalence and Risk Factors of Central Venous Stenosis among Prevalent Hemodialysis Patients, a Single Center Experience.
    Arab J Nephrol Transplant 2014 Jan;7(1):45-7
    Ahmed Gasim Cardiac Surgery and Renal Transplant Center, Khartoum, Sudan.
    Introduction: Central vein stenosis (CVS) is a common complication of central venous catheter (CVC) insertion. In this study we evaluated the prevalence and risk factors of CVS among hemodialysis (HD) patients in a single center in Sudan, using Doppler ultrasound as a screening tool.

    Methods: The study included 106 prevalent HD patients. Read More

    Acute pancreatitis: a rare complication in a patient with senior loken syndrome.
    Arab J Nephrol Transplant 2014 Jan;7(1):41-3
    Pediatric Nephrology Department, Charles Nicolle Hospital, Tunisia.
    Introduction: Senior-Loken syndrome is a rare entity that combines familial nephronophthisisand retinal dystrophy. It has an autosomal recessive inheritance pattern and is characterized by a chronic tubulointerstitial nephritis that progress to terminal renal failure during the first or second decades of life. Systemic associations of this syndrome include sensorineural hearing loss, liver fibrosis or cerebral vermis hypoplasia. Read More

    Lupus nephritis emerging during remission of minimal change disease.
    Arab J Nephrol Transplant 2014 Jan;7(1):37-40
    Department of Nephrology, Dialysis and Transplantation, Military Hospital Mohammed V, Rabat, Morocco.
    Introduction: Rare cases of association between lupus nephritis (LN) and minimal changes nephrotic syndrome (MCNS) were described. Some authors suggest that this association, taking into account the low prevalence of both diseases, may not be a simple coincidence. Several pathophysiological hypotheses have been proposed to explain this association, including a potential central role of T lymphocytes. Read More

    Pelvi-Ureteric Junction Obstruction at Red Cross Children's Hospital, Cape Town: a Six Year Review.
    Arab J Nephrol Transplant 2014 Jan;7(1):33-6
    Red Cross Children's Hospital, Cape Town, South Africa.
    Introduction: Congenital abnormalities of the kidney and urinary tract (CAKUT) are significant causes of end stage renal disease (ESRD) in children. Some of these abnormalities, when identified early, are amenable to treatment. In developing countries, very few published reports exist concerning the pattern and scope of CAKUT in childhood. Read More

    Experience in using thermal disinfection to remove viable bacteria and endotoxins in centraly distributed reverse osmosis water.
    Arab J Nephrol Transplant 2014 Jan;7(1):27-31
    Service of Nephrology, Hemodialysis and Kidney Transplantation, Military Hospital, Mohammed V. Rabat, Morocco.
    Introduction: The water used for dilution of hemodialysis concentrates has to meet official quality recommendations regarding microbiology and chemical parameters. To avoid chemical use and to simplify treatments, hot water has been used to control microbial contamination of water distribution systems. In this study we evaluated the efficacy of heat disinfection in maintaining the quality of dialysis water generated by reverse osmosis (RO). Read More

    Histopathological Association between Vascular Hypertensive Changes and Different Types of Glomerulopathies.
    Arab J Nephrol Transplant 2014 Jan;7(1):21-6
    Departments of Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
    Introduction: The term hypertensive nephrosclerosis has traditionally been used to describe a clinical syndrome characterized by long-term essential hypertension, hypertensive retinopathy, left ventricular hypertrophy, minimal proteinuria, and progressive renal insufficiency. In the absence of renal biopsy, the diagnosis of hypertensive nephrosclerosis is one of exclusion.

    Methods: We retrospectively studied 735 patients who had renal biopsies at Ain Shams University Hospitals between January 2008 and Dec 2010. Read More

    Management of Anemia and other Hematologic Derangements in Patients with Chronic Kidney Disease.
    Arab J Nephrol Transplant 2014 Jan;7(1):13-9
    Dow University of Health Sciences, Karachi,Pakistan.
    Introduction: Chronic Kidney Disease (CKD) has adverse consequences on almost all body systems. The kidney does not function merely as an excretory organ, but participates in normal erythropoiesis, normal bone mineral deposition and blood pressure regulation.

    Review: Anemia is prevalent in CKD with known deleterious effects on the car diovascular system. Read More

    Chronic kidney Disease and the Aging Population.
    Arab J Nephrol Transplant 2014 Jan;7(1):7-11
    Catholic University of Parana, Curitiba, Brazil.
    Youth, which is forgiven everything, forgives itself nothing: age, which forgives itself everything, is forgiven nothing. George Bernard Shaw The proportion of older people in the general population is steadily increasing worldwide, with the most rapid growth in low-and middle-income countries [1]. This demographic change is to be celebrated, because it is the consequence of socioeconomic development and better life expectancy. Read More

    A preliminary survey of un-diagnosed hypertension among Nubians and Coptics in Atbara and Eldamer Cities, Sudan: does ethnicity affect prevalence?
    Arab J Nephrol Transplant 2013 Sep;6(3):193-5
    Faculty of Medicine and Health Sciences, Nile Valley University, Atbara, Sudan.
    Introduction: Hypertension is a non-communicable disease of increasing importance in developing countries. Due to its silent nature and serious complications, active screening is essential in case detection. The aim of this study was to determine the prevalence of undiagnosed hypertension and to find out whether there are ethnic variations in prevalence between two Sudanese ethnicities. Read More

    Prevalence of non-communicable diseases and its awareness among inhabitants of Sokoto metropolis: outcome of a screening program for hypertension, obesity, diabetes mellitus and overt proteinuria.
    Arab J Nephrol Transplant 2013 Sep;6(3):189-91
    Departments of Medicine, Usmanu Danfodiyo University Teaching Hospital, Sokoto,Nigeria.
    Introduction: Developing countries confront double jeopardy of prevalent infectious disease and increasing Non-Communicable Diseases (NCD) with imminent projected epidemic proportions. Nigeria has witnessed tremendous socio-economic changes and rural to urban migration culminating in emergence of NCD. The impact of these diseases on the lives of people is enormous when measured in terms of outcomes. Read More

    Nephrogenic diabetes insipidus with intracranial calcification in a child with thalassemia minor.
    Arab J Nephrol Transplant 2013 Sep;6(3):185-7
    Department of Pediatrics, Lokmanya Tilak Municipal medical college and general hospital, Sion, Mumbai - 400022, India.
    Introduction: There are numerous causes for intracranial calcification in children. We describe an unusual cause of intracranial calcification in a child, namely, nephrogenic diabetes insipidus (NDI).

    Case Report: A 12-year-old boy presented with seizures and developmental delay. Read More

    Idiopathic membranous nephropathy preceding the onset of rheumatoid arthritis: a case report.
    Arab J Nephrol Transplant 2013 Sep;6(3):181-4
    Unit of Nephrology, Ibn Sina University Hospital, Rabat, Morocco.
    Introduction: Membranous nephropathy (MN) in the context of rheumatoid arthritis (RA), is often an iatrogenic complication due to the nephrotoxic effects of antirheumatic drugs. Rare cases of non-iatrogenic association between these two diseases were reported in the literature.

    Case Report: A 30-year-old female patient presented in September 2005 with nephrotic syndrome. Read More

    Acute tubulo-interstitial nephritis with positive anti-neutrophil cytoplasmic antibodies.
    Arab J Nephrol Transplant 2013 Sep;6(3):177-9
    Department of Nephrology, Dialysis and Transplantation, Military Training Hospital Mohammed V, Rabat, Morocco.
    Introduction: Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis involving the kidney usually comprises pauci-immune, necrotizing glomerulonephritis with crescents. Mononuclear tubulo-interstitial infiltrates are common in ANCA associated vasculitis, but these have usually been described in conjunction with glomerulitis. Acute tubulo-interstitial nephritis (ATIN) is a common cause of acute kidney injury that is most frequently induced by drugs or infections. Read More

    Acupuncture efficacy in the treatment of persistent primary nocturnal enuresis.
    Arab J Nephrol Transplant 2013 Sep;6(3):173-6
    Departments of Pediatrics, Faculty of Medicine, Zagazig University, Egypt.
    Introduction: This study aimed to assess the therapeutic efficacy of traditional Chinese acupuncture in the treatment of persistent primary nocturnal enuresis (PNE).

    Methods: Fifty children and adolescents suffering from persistent PNE were recruited from the Pediatrics and Urology Outpatient Clinic of Zagazig University Hospital during the year 2010. They included 31 boys and 19 girls, with a mean age of 116 ± years (range 9-17 years). Read More

    Depression in Iraqi hemodialysis patients.
    Arab J Nephrol Transplant 2013 Sep;6(3):169-72
    Department of Neuropsychiatry, Baghdad Teaching Hospital, Baghdad, Iraq.
    Introduction: Affective disorders, particularly depression, are the commonest and probably the most important psychopathological complication of end stage renal disease (ESRD). Depression has the potential to alter adversely the medical outcome of ESRD patients and the psychological stress can affect patient's adherence to medication regimen. In Iraq as well as many other Arab countries, the true prevalence of depression among ESRD patients is unknown. Read More

    The spectrum of glomerular diseases as studied by immunofluorescence microscopy a single center study in Iraq.
    Arab J Nephrol Transplant 2013 Sep;6(3):161-7
    Assistant Professor of Medicine and Nephrology, University of Kerbala, Kerbala, Iraq.
    Introduction: Immunofluorescence (IF) microscopy is an important tool for the diagnosis of glomerular diseases. In this study, we focused on using IF technique together with light microscopy (LM) and clinical features in the diagnosis of different types of glomerulonephritis (GN). We aimed to evaluate the spectrum of glomerular diseases in our center and compare it with other centers in Iraq as well as in other countries. Read More

    Dense deposit disease: a 29-years electron microscopy experience.
    Arab J Nephrol Transplant 2013 Sep;6(3):153-60
    Electron microscopy unit, Department of Pathology, Ain Shams University Specialized Hospital (ASUSH), Cairo, Egypt.
    Introduction: Dense Deposit Disease (DDD) is a devastating renal disease that leads to renal failure within 10 years of diagnosis in about half of affected patients. In this study, we evaluated the relative prevalence and pathological features of DDD diagnosed at our center over a 29 years period.

    Methods: We reviewed the clinical and pathological features of all cases of DDD diagnosed at the Electron Microscopy Unit of Ain Shams University (ASUSH) between January 1983 and December 2011. Read More

    The definitions and staging systems of acute kidney injury and their limitations in practice.
    Arab J Nephrol Transplant 2013 Sep;6(3):145-52
    Former Chief of the Renal Division, University Hospital, Belgium.
    Introduction: It is now evident that even minimal reductions in glomerular filtration rate (GFR) are associated with a dramatic increase in mortality. The term acute kidney injury (AKI) describes an acute fall of estimated GFR (eGFR) and allows patient stratification based on AKI severity.

    Review: The Risk, Injury, Failure, Loss and End-stage kidney disease (RIFLE) system defines AKI by a change in serum creatinine (SCr) level or eGFR from a baseline value, and urine output per kilogram of body weight over a specified time period. Read More

    Acute kidney injury: global health alert.
    Arab J Nephrol Transplant 2013 May;6(2):75-81
    Acute kidney injury (AKI) is increasingly prevalent in developing and developed countries and is associated with severe morbidity and mortality. Most etiologies of AKI can be prevented by interventions at the individual, community, regional and in-hospital levels. Effective measures must include community-wide efforts to increase an awareness of the devastating effects of AKI and provide guidance on preventive strategies, as well as early recognition and management. Read More

    Evaluation of nurses awareness and practice of hemodialysis access care in Khartoum state, Sudan.
    Arab J Nephrol Transplant 2013 May;6(2):119-21
    Faculty of Nursing Sciences, National Ribat University, Khartoum, Sudan.
    Introduction: In hemodialysis (HD) wards, nurses play a pivotal role in HD access care. Unfortunately, guideline recommendations for routine preventive care are not always followed. This study was designed to evaluate nurses' awareness and practice of HD access care in Khartoum state, Sudan. Read More

    Severe tricuspid valve endocarditis related to tunneled catheters in chronic hemodialysis patients: when should the catheter be removed?
    Arab J Nephrol Transplant 2013 May;6(2):115-18
    MedicalSchool, University Mohamed First, Oujda, Morocco.
    Introduction: Hemodialysis (HD) patients are predisposed to infective endocarditis (IE) mainly due to repeated manipulation of the vascular access. However, catheter seeding and IE may also result from a distant infection site.

    Case Series: A diabetic patient who was maintained on regular HD through a permanent catheter in the right internal jugular vein presented with septicemia of urinary origin due to Pseudomonas aeruginosa. Read More

    Epidemiology and clinicopathologic outcome of pediatric chronic kidney disease in Nigeria, a single cenetr study.
    Arab J Nephrol Transplant 2013 May;6(2):105-13
    Pediatric Nephrology and Hypertension Unit, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria.
    Introduction: Due to dearth of data, chronic kidney disease (CKD) outcome in African children has been dismal owing to poor understanding of its etiology, manifestations and management.

    Methods: We retrospectively analyzed the records of 154 CKD children and adolescents who were managed at Obafemi Awolowo University Teaching Hospitals Complex between 2000 and 2009 to evaluate the epidemiology and clinicopathologic outcome of pediatric CKD in Nigeria.

    Results: Overall mean incidence was 11 (6-20) per million children population (pmcp)/year while prevalence averaged 48 (8-101) pmcp. Read More

    Adherence of healthcare professionals to evidence-based clinical practice guidelines in the management of hemodialysis patients, Khartoum State, Sudan.
    Arab J Nephrol Transplant 2013 May;6(2):99-104
    Khartoum Teaching Hospital, Ministry of Health, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
    Introduction: Hemodialysis (HD) is a complex procedure with many specifications and requires adherence to a set of particular clinical practice guidelines. These guidelines had already been established by globally acclaimed renal authorities and their implementation was shown to correlate with patients' morbidity and mortality. This study was conducted to evaluate the adherence of healthcare professionals to the evidence-based clinical practice patterns in Khartoum State HD units. Read More

    Parameters to assess nutritional status in a Moroccan hemodialysis cohort.
    Arab J Nephrol Transplant 2013 May;6(2):89-97
    Department of Nephrology, Dialysis and Renal Transplantation, Military Hospital Mohammed V, Hay Riad, Rabat, Morocco.
    Introduction: Malnutrition is common in maintenance hemodialysis (HD) and is associated with increased mortality and morbidity in affected patients. The aim of this study was to determine the prevalence of malnutrition and correlate the methods of nutritional assessment.

    Methods: We evaluated the nutritional status of 40 prevalent HD patients by subjective global assessment (SGA) score, anthropometrics [body mass index (BMI), arm circumference (AC), triceps skin-fold thicknesses (TSF), arm muscle circumference (AMC)], biochemical tests [normalized protein equivalent to total nitrogen appearance (nPNA), and pre-dialysis serum albumin and serum prealbumin levels] and bio-electrical impedance (BEI) analysis to estimate body composition [lean tissue index (LTI) and fat tissue index (FTI)]. Read More

    Type 1/type 2 cytokine serum levels and role of interleukin-18 in children with steroid-sensitive nephrotic syndrome.
    Arab J Nephrol Transplant 2013 May;6(2):83-8
    College of Medicine, Taibah University, and Maternity and Children Hospital, AL-Madinah AL-Munawarah, Kingdom of Saudi Arabia.
    Introduction: In view of the conflicting evidence of helper T cell type 1 (Th1) or type 2 (Th2) pattern of cytokine synthesis in steroid sensitive nephrotic syndrome (SSNS), this study aimed to assess type-1/type-2 cytokines level in different stages of SSNS and to evaluate the role of IL-18.

    Methods: We prospectively studied thirty children with SSNS, aged 2-12 years. The children were evaluated in the active stage before treatment initiation and re-evaluated again during remission while still on steroid treatment. Read More

    The potential role of nursing students in the implementation of community-based hypertension screening programs in Sudan.
    Arab J Nephrol Transplant 2013 Jan;6(1):51-4
    Faculty of Nursing Sciences of National Ribat University and Sudan-PD Program, Khartoum, Sudan.
    Introduction: Hypertension (HTN), diabetes mellitus (DM) and chronic kidney disease (CKD) are important health problems worldwide, and it is possible to reduce their burden through effective HTN screening and treatment programs. It may be feasible to incorporate such programs in the community outreach activities of nursing and medical schools in Sudan.

    Methods: Village inhabitants in the Northern state of Sudan were invited to attend a free clinic for screening of hypertension as well as for follow up and treatment of persons with previously diagnosed hypertension. Read More

    Chronic renal allograft dysfunction: risk factors, immunology and prevention.
    Arab J Nephrol Transplant 2013 Jan;6(1):45-50
    Nephrology and Kidney Transplantation, Medical University Hospital, University Caddi Ayad, Marrakech, Morocco.
    Introduction: Kidney transplantation is the treatment of choice for patients with end-stage renal disease. Despite great progress in surgical aspects and immunosupression therapy, long-term graft survival has not been consistent. Chronic allograft dysfunction (CAD) remains a major cause of late grafts failure. Read More

    Treatment of hepatitis B virus reactivation in a cadaveric renal transplant recipient with entecavir.
    Arab J Nephrol Transplant 2013 Jan;6(1):41-4
    Department of Urology and Transplantation, Beaumont Hospital, Dublin, Ireland.
    Introduction: Risk of reactivation of Hepatitis B virus (HBV) infection and other liver related complications continues to be a major cause of concern in HBV carriers undergoing cadaveric renal transplantation. Antiviral medications have been recommended post renal transplantation in patients who are chronic HBV carriers.

    Case Report: Here we present the case of a 15-year-old girl known to have kidney failure and chronic active HBV infection indicated by positivity of both HBsAg and HBeAg. Read More

    Gitelman syndrome as a cause of psychomotor retardation in a toddler.
    Arab J Nephrol Transplant 2013 Jan;6(1):37-9
    Department of Pediatrics, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czech Republic.
    Introduction: Gitelman syndrome (GS) is a very rare autosomal recessive tubulopathy due to loss-of-function or mutation in solute carrier family12, member 3 gene (SLC12A3 gene) encoding thiazide-sensitive NaCl co-transporter in the distal convoluted tubule, leading to hypokalemia, metabolic alkalosis, hypomagnesemia, hypocalciuria and low-to-normal blood pressure. Clinical signs are mostly secondary to chronic hypokalemia and include dizziness, fatigue, constipation and weakness. Patients can also present with muscle cramps, tetany, fatigue and convulsions due to severe metabolic alkalosis or hypomagnesemia. Read More

    ANCA negative pulmonary renal syndrome with pathologic findings of thrombotic microangiopathy.
    Arab J Nephrol Transplant 2013 Jan;6(1):31-5
    Department of Nephrology, Theodor Bilharz Research Institute, Cairo, Egypt.
    Introduction: Thrombotic microangiopathy (TMA) is characterized by aggregation of platelets in the renal and/or systemic circulation, thrombocytopenia and intravascular hemolysis. The syndrome classically spares the lung. The term pulmonary-renal syndrome describes a number of diseases in which pulmonary hemorrhages and glomerulopathy coexist. Read More

    Urinary albumin and interleukin-8 levels are not good indicators of ongoing vesicoureteral reflux in children who have no active urinary tract infection.
    Arab J Nephrol Transplant 2013 Jan;6(1):27-30
    Gilan University of Medical Sciences and Gilan Pediatrics Growth Disorder Research Center, Rasht, Iran.
    Introduction: Vesicoureteral reflux (VUR) is a risk factor for kidney scarring, hypertension and declining renal function. Standard diagnostic methods are invasive and can cause exposure to radiation and urinary tract infections (UTIs). We aimed to investigate urine albumin and interleukin-8 levels as markers of ongoing VUR and renal damage in children without UTIs. Read More

    Cystatin C as an early marker of acute kidney injury and predictor of mortality in the intensive care unit after acute myocardial infarction.
    Arab J Nephrol Transplant 2013 Jan;6(1):21-6
    Internal Medicine Department, Zagazig University Hospital, Zagazig, Egypt.
    Introduction: Early detection of Acute Kidney Injury (AKI) is important. We conducted a prospective observational study to test the ability of cystatin C (CysC) to predict AKI and mortality among in intensive care unit (ICU) patients after acute myocardial infarction (MI).

    Methods: One hundred patients were enrolled in this study, CysC and serum creatinine (SCr) were measured at admission in the ICU and then daily for three days. Read More

    Negative correlation between fetuin-A and indices of vascular disease in systemic lupus erythematosus patients with and without lupus nephritis.
    Arab J Nephrol Transplant 2013 Jan;6(1):11-20
    Department of Pharmacology, Cairo University, Cairo, Egypt.
    Introduction: Fetuin-A, a systemic calcification inhibitor, has been negatively related to vascular calcification (VC) and cardiovascular mortality. In this study we investigated the association between fetuin-A levels and atherosclerotic vascular complications in systemic lupus erythematosus (SLE) patients with and without lupus nephritis (LN).

    Methods: We recruited 20 SLE patients without LN, 20 SLE patients with LN and 20 healthy controls. Read More

    Posterior reversible encephalopathy syndrome in a child with steroid sensitive nephrotic syndrome.
    Arab J Nephrol Transplant 2012 Sep;5(3):163-6
    Pediatrics Department, Zagazig University Hospital, Cairo, Egypt.
    Introduction: Posterior reversible encephalopathy syndrome (PRES) was described in adults more than children. It was reported in cases of nephrotic syndrome which were mainly on immunosuppressant medications or had severe hypertension.

    Case Report: We report the case of a 9-years old girl who presented with nephrotic syndrome and moderate hypertension. Read More

    Acute renal failure following the Saharan horned viper (Cerastes cerastes) bite.
    Arab J Nephrol Transplant 2012 Sep;5(3):159-61
    Department of Nephrology, Military Hospital Mohammed V, Rabat, Morocco.
    Introduction: The Saharan horned viper (Cerastes cerastes) is a common snake in the sandy and rocky regions in the south of Morocco. Although nearly all snakes with medical relevance can induce acute renal failure (ARF), it's unusual except with bites by some viper species. ARF has very rarely been reported following Cerastes cerastes bite. Read More

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