379 results match your criteria Arab Journal Of Gastroenterology[Journal]


Virulent Escherichia coli strains among Egyptian patients with acute diarrhoea versus urinary tract infection, and their antibiotic susceptibility.

Arab J Gastroenterol 2019 Mar 21. Epub 2019 Mar 21.

Botany and Microbiology Department, Faculty of Science, Cairo University, Cairo, Egypt.

Background And Study Aims: Diarrhoea and urinary tract infection (UTI) are common clinical problems. Meanwhile, Escherichia coli (E. coli), is the commonest bacterial pathogen reported in both of them. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.003DOI Listing
March 2019
4 Reads

Relationship between lifestyle factors and nutritional status and non-alcoholic fatty liver disease among a group of adult Jordanians.

Arab J Gastroenterol 2019 Mar 11;20(1):44-49. Epub 2019 Mar 11.

Department of Gastroenterology & Hepatology, School of Medicine, University of Jordan, Amman, Jordan.

Background And Study Aims: Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. NAFLD may progress from simple steatosis to nonalcoholic steatohepatitis, cirrhosis and finally decompensated liver failure. This study aims at assessing the relationship between lifestyle factors and nutrients intake and the development of non-alcoholic fatty liver disease (NAFLD) in a group of Jordanian adults 30-60 years of age. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.008DOI Listing
March 2019
3 Reads

ERCP quality indicators: The experience of a high-volume tertiary care center in Saudi Arabia.

Arab J Gastroenterol 2019 Mar 11;20(1):32-37. Epub 2019 Mar 11.

King Fahad Medical City, Department of Gastroenterology and Hepatology, Riyadh, Saudi Arabia. Electronic address:

Background: Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most technically demanding and high-risk procedures performed by GI endoscopists. Therefore, guidelines or position statements on various aspects of quality indicators, safety indicators and credentialing for ERCP have been developed by gastroenterology associations. In this paper, we evaluate the ERCP quality in a single, high-volume, tertiary care center in Saudi Arabia using a number of measures commonly stated by these organizations, and compare the experience of that center to the previously-published standards in this regard. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.005DOI Listing
March 2019
1 Read

Lamivudine use in pregnant HBsAg-females effectively reduces maternal viremia.

Arab J Gastroenterol 2019 Mar 8;20(1):8-13. Epub 2019 Mar 8.

Department of Clinical Chemistry, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.

Background And Study Aims: Mother-infant hepatitis B virus (HBV) transmission is the current leading cause of chronic infection. We aimed to assess the efficacy of lamivudine use in hepatitis B surface antigen (HBsAg)-positive pregnant women to decrease viral load and thus aid in the prevention of transmission.

Patients And Methods: A study of 73 mother-infant pairs. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.02.003DOI Listing

Hepatocellular carcinoma in a rapidly growing community: Epidemiology, clinico-pathology and predictors of extrahepatic metastasis.

Arab J Gastroenterol 2019 Mar 8;20(1):38-43. Epub 2019 Mar 8.

Department of Surgery, Hamad Medical Corporation, Doha, Qatar.

Background And Study Aims: Hepatocellular carcinoma (HCC) with extrahepatic metastasis has been studied, however, data from the Middle East remain scarce. In this study, we assess epidemiology of HCC in Qatar, and identify predictors of the metastatic behaviour.

Patients And Methods: All newly-diagnosed HCC patients on top of liver cirrhosis between 2011 and 2015 were included in the study. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.006DOI Listing
March 2019
9 Reads

Hydatid disease of the liver with portal vein invasion mimicking portal vein thrombosis.

Arab J Gastroenterol 2019 Mar 8;20(1):50-52. Epub 2019 Mar 8.

Department of Radiology, Istanbul Medipol University School of Medicine, Istanbul, Turkey.

Hydatid cyst disease is a zoonosis caused by the parasite Echinococcus. It may infest any organ of the body, but it most frequently involves the liver, lungs, and nervous system. Portal vein involvement by hydatid cyst disease is extremely rare with only five cases published in the English literature to our knowledge. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.010DOI Listing

Circulating microRNA-155 is associated with insulin resistance in chronic hepatitis C patients.

Arab J Gastroenterol 2019 Mar 7;20(1):1-7. Epub 2019 Mar 7.

Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Egypt. Electronic address:

Background And Study Aim: Hepatitis C represents a potential public health problem worldwide. Insulin resistance (IR) and type 2 diabetes (T2D) are among the serious metabolic complications for chronic hepatitis C virus (HCV) infection. MicroRNAs (miRNAs) are a group of small non-coding RNAs which are implicated in the modulation of almost all biological processes. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.011DOI Listing

Postanal minimally invasive surgery "PAMIS" assisted extra-levator abdominoperineal excision "ELAPE" for cancer: A novel approach in supine position.

Authors:
Ahmed Farag

Arab J Gastroenterol 2019 Mar 12;20(1):53-55. Epub 2019 Feb 12.

Faculty of Medicine, Cairo University, Egypt. Electronic address:

Local recurrences are more common after abdominoperineal excision (APE) than after anterior resection of rectal cancer. Extralevator APE was introduced to address this problem. The post anal minimally invasive approach had been used by other authors for transperineal mesh rectopexy but not in cancer management. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.02.001DOI Listing
March 2019
2 Reads

Prognostic factors in patients with active non-variceal upper gastrointestinal bleeding.

Arab J Gastroenterol 2019 Mar 12;20(1):23-27. Epub 2019 Feb 12.

Department of Internal Medicine, Metabolic Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. Electronic address:

Background And Study Aims: Acute upper gastrointestinal bleeding is one of the main causes of hospitalisation. The purpose of this study was to determine the prognostic factors in non-variceal upper gastrointestinal bleeding.

Patients And Methods: Clinical outcomes, demographic and laboratory variables of the subjects were collected from the HIS software and national code with the SQL format from three hospitals in Qazvin. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.001DOI Listing
March 2019
1 Read

Fiducial placement for recurrent gastric cancer.

Arab J Gastroenterol 2019 Mar 8;20(1):56-58. Epub 2019 Feb 8.

Division of Internal Medicine, East Carolina University, Greenville, NC, USA.

A 53-year-old male was diagnosed with invasive adenocarcinoma of the pre-pyloric region. Imaging studies ruled out metastatic disease. The patient underwent neo-adjuvant chemotherapy followed by a partial gastrectomy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16871979193000
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http://dx.doi.org/10.1016/j.ajg.2019.01.007DOI Listing
March 2019
1 Read

Paraoxonase-1 and arylesterase levels in patients with ulcerative colitis.

Arab J Gastroenterol 2019 Mar 8;20(1):14-18. Epub 2019 Feb 8.

Department of Gastroenterology, Mersin University, Mersin, Turkey.

Background And Study Aims: The role of oxidative stress in inflammatory bowel disease is increasingly recognised as an important factor. It is assumed that reduced levels of paraoxonase-1 (PON-1) and arylesterase (ARE) may lead to increased inflammation due to increased oxidative stress. This study aimed to investigate the relationship between ARE and PON-1 levels in ulcerative colitis (UC) patients and the difference in these levels in UC patients in comparison to the control group. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.009DOI Listing
March 2019
14 Reads

Metastatic melanoma to the jejunum.

Authors:
Amer A Alkhatib

Arab J Gastroenterol 2019 Feb 4. Epub 2019 Feb 4.

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195-0001, USA; Department of Gastroenterology, Cleveland Clinic Abu Dhabi, United Arab Emirates. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S16871979183011
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http://dx.doi.org/10.1016/j.ajg.2018.12.005DOI Listing
February 2019
9 Reads

Primary omental malignant solitary fibrous tumour, an extremely rare malignancy: A case report and review of the literature.

Arab J Gastroenterol 2019 Feb 4. Epub 2019 Feb 4.

Department of Surgery, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Nam-gu, Daegu 42415, Republic of Korea. Electronic address:

Primary omental malignant solitary fibrous tumour is an extremely rare neoplasm considering its tumour origin and pathologic characteristics. Solitary fibrous tumour (SFT) is a spindle cell neoplasm that was first described in 1931. SFT is diagnosed at immunohistochemical stain including CD34, bcl2, CD99 and STAT6. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.12.001DOI Listing
February 2019

Self-expandable metal stent for dysphagia caused by mediastinal masses in patients with lung cancer.

Arab J Gastroenterol 2019 Mar 4;20(1):28-31. Epub 2019 Feb 4.

Endoscopy Unit, Department of Gastroenterology and Hepatology, University Hospital Centre Zagreb, Croatia.

Background And Study Aims: We intended to evaluate the role of self-expandable metal stents (SEMS) for palliation of malignant dysphagia in patients with lung cancer.

Patients And Methods: During the period between May 2015 and September 2017, 42 SEMS have been placed for malignant dysphagia in patients with lung cancer. Stents have been placed under combined fluoroscopic and endoscopic guidance. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.01.004DOI Listing
March 2019
1 Read

Colocolic intussusception.

Arab J Gastroenterol 2019 Feb 4. Epub 2019 Feb 4.

Division of Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.ajg.2018.12.003DOI Listing
February 2019

Colonization of intestinal microbiota with carbapenemase-producing Enterobacteriaceae in paediatric intensive care units in Cairo, Egypt.

Arab J Gastroenterol 2019 Mar 4;20(1):19-22. Epub 2019 Feb 4.

Botany and Microbiology Department, Faculty of Science, Cairo University, Cairo, Egypt.

Background And Study Aims: Colonized patients with carbapenamase producing Enterobacteriaceae (CPE) are vulnerable to invasive infections from their endogenous flora. We aimed to assess faecal colonization with (CPE) among children admitted to Cairo University paediatric intensive care units (ICUs). The phenotypic and genotypic characterizations of carbapenemase-producing Enterobacteriaceae were also studied. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16871979193000
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http://dx.doi.org/10.1016/j.ajg.2019.01.002DOI Listing
March 2019
4 Reads

Incomplete cold snare polypectomy for rectal carcinoid tumour.

Arab J Gastroenterol 2019 Mar 4;20(1):59-60. Epub 2019 Feb 4.

Department of Gastroenterology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Gunma, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ajg.2018.12.002DOI Listing

The association between blood urea nitrogen to creatinine ratio and mortality in patients with upper gastrointestinal bleeding.

Arab J Gastroenterol 2018 Dec 3;19(4):143-147. Epub 2018 Dec 3.

Department of Emergency Medicine, Chang Gung Memorial Hospital, No. 6, W. Sec., Jiapu Rd., Puzih City, Chiayi County 613, Taiwan; Department of Nursing, Chang Gung University of Science and Technology, Chiayi Campus, Chiayi, Taiwan. Electronic address:

Background And Study Aims: Azotaemia is commonly identified among patients with upper gastrointestinal bleeding (UGIB) due to absorption of blood products in the small bowel. Previous studies have found blood urea nitrogen-to-creatinine (BUN/Cr) ratio to be significantly elevated among patients UGIB bleeding compared to patients with lower GI bleeding. However, no studies have explored the relationship between BUN/Cr ratio and mortality. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.11.002DOI Listing
December 2018
2 Reads

Characterization of PI3KCA and BRAF mutations in gastric adenocarcinoma: An approach to a personalized targeted therapy for Moroccan HER2 overexpressed patients.

Arab J Gastroenterol 2018 Dec 28;19(4):155-158. Epub 2018 Nov 28.

Laboratory of Anatomy Pathology, Pasteur Institue, 20100, Morocco.

Background And Study Aims: Targeted therapies have an increasing importance in digestive oncology. To our knowledge, we are the first to report the distribution of PI3KCA and BRAF mutations in Moroccan HER2 overexpressed patients, in order to introduce targeted therapy in the arsenal of therapeutic modalities for management in Morocco.

Patients And Methods: 98 gastric adenocarcinoma tissue samples were collected. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16871979183006
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http://dx.doi.org/10.1016/j.ajg.2018.08.001DOI Listing
December 2018
1 Read

Highlights from Gastro Update Europe - Prague, June 2018.

Authors:
Guido N J Tytgat

Arab J Gastroenterol 2018 Dec 30;19(4):159-165. Epub 2018 Nov 30.

Division of Gastroenterology-Hepatology, Amsterdam UMC-location Academic Medical Center, Meibergdreef, 1105 AZ Amsterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajg.2018.09.002DOI Listing
December 2018

Correlation between expression of MMP-9 and MMP-3 in Helicobacter pylori infected patients with different gastroduodenal diseases.

Arab J Gastroenterol 2018 Dec 30;19(4):148-154. Epub 2018 Nov 30.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address:

Background And Study Aims: Helicobacter pylori (H. pylori) has been implicated in the pathogenesis of most important gastro-duodenal diseases, such as gastritis, peptic ulcer disease (PUD) and gastric cancer. H. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.11.001DOI Listing
December 2018
2 Reads

Managing diabetes and liver disease association.

Arab J Gastroenterol 2018 Dec 9;19(4):166-179. Epub 2018 Nov 9.

Kasr Al Aini, Egypt.

There is strong association between liver diseases and diabetes (DM) which is higher than expected by a chance association of two very common disorders. It can be classified into three categories: Liver disease related to diabetes, hepatogenous diabetes (HD), and liver disease occurring coincidentally with DM. The criteria for the diagnosis of diabetes associating liver disease are the same for primary diabetes. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.08.003DOI Listing
December 2018
17 Reads

Evaluation of interleukin 23 (IL-23) as a non-invasive test of disease severity in patients with ulcerative colitis.

Arab J Gastroenterol 2018 Sep 27;19(3):116-120. Epub 2018 Sep 27.

Departments of Internal Medicine, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.

Background And Study Aims: Studies have found increased expression of IL-23 in inflamed and non-inflamed mucosa of patients with ulcerative colitis (UC). We hypothesized that serum interleukin-23 as a non-invasive test has a role in pathogenesis of ulcerative colitis disease and correlates with the disease severity.

Patients And Methods: Forty patients with biopsy proven ulcerative colitis, recruited from Ain Shams University hospitals were included. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.09.003DOI Listing
September 2018
6 Reads

Retroperitoneal choriocarcinoma diagnosed by endoscopic ultrasonography-guided fine needle aspiration biopsy.

Arab J Gastroenterol 2018 Sep 24;19(3):130-133. Epub 2018 Sep 24.

Division of Endoscopy, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka 411-8777, Japan.

A 25-year-old man, with a retroperitoneal bulky mass invading the posterior pancreas head, was referred to investigate and treat his rapidly advancing disease. An endoscopic ultrasonography guided-fine needle aspiration biopsy (EUS-FNAB), performed the next day, and followed by immunostaining for human chorionic gonadotropin (hCG), led to a histological diagnosis of choriocarcinoma. An elevated level of serum hCG also supported the diagnosis. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.08.005DOI Listing
September 2018
1 Read

Tomosynthesis for colonic localization of patency capsules.

Arab J Gastroenterol 2018 Sep 24;19(3):134-135. Epub 2018 Sep 24.

Institute of Gastroenterology, Tokyo Women's Medical University, Japan.

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http://dx.doi.org/10.1016/j.ajg.2018.08.006DOI Listing
September 2018

Two novel SNPs in the promoter region of PKR gene in hepatitis C patients and their impact on disease outcome and response to treatment.

Arab J Gastroenterol 2018 Sep 20;19(3):106-115. Epub 2018 Sep 20.

Microbiology and Immunology Department, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt.

Background And Study Aims: The double-stranded RNA dependent protein kinase (PKR) plays a vital role in the immune system. During HCV infection, PKR has antiviral effect by inhibition of protein synthesis of the HCV. The functional single nucleotide polymorphisms (SNPs) in PKR promoter region might have a relation to HCV disease outcome and response to treatment. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.06.002DOI Listing
September 2018
1 Read

Occult hepatitis C virus infection among haemodialysis patients.

Arab J Gastroenterol 2018 Sep 20;19(3):101-105. Epub 2018 Sep 20.

Clinical Pathology and Chemistry Unit, National Center for Radiation Research and Technology, Atomic Energy Authority, Cairo, Egypt.

Background And Study Aims: Hepatitis C virus (HCV) infection is a severe problem among patients on maintenance haemodialysis who are at particular risk for blood-borne infections because of prolonged vascular access and potential for exposure to contaminated equipment. Occult hepatitis C virus infection (OCI) is defined as the presence of HCV RNA in liver or peripheral blood mononuclear cells (PBMCs) in the absence of detectable HCV antibody or HCV RNA in the serum. In this study, we aimed to investigate the existence of occult hepatitis C virus infection in PBMCs of haemodialysis (HD) patients in one center. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.09.001DOI Listing
September 2018

Expression of epidermal growth factor receptor (EGFR) in colorectal cancer: An immunohistochemical study.

Arab J Gastroenterol 2018 Sep 20;19(3):121-124. Epub 2018 Sep 20.

Pathology Department in Habib Thameur Hospital and Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.

Background And Study Aim: The epidermal growth factor receptor (EGFR) plays an important role in tumourigenesis and tumour progression of colorectal cancer (CRC) and leads to the activation of intracellular signaling pathways. The use of anti-EGFR-targeted therapy has increased for patients with metastatic CRC. Today, the clinical utility of immunohistochemistry has remained somewhat inconclusive. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.08.002DOI Listing
September 2018
2 Reads

Giant duodenal Brunner's gland hamartoma successfully treated via endoscopic mucosal resection.

Arab J Gastroenterol 2018 Sep 20;19(3):125-129. Epub 2018 Sep 20.

Department of Gastroenterology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.

We describe a patient with a giant Brunner's gland hamartoma in the duodenum who was safely treated by endoscopic mucosal resection (EMR). A 64-year-old woman visited our hospital for a workup of severe anaemia (haemoglobin level: 5 g/dL). Oesophagogastroduodenoscopy revealed a large pedunculated and elongated polypoid lesion measuring approximately 70 mm in longitudinal diameter, located at the anterior wall of the duodenal bulb. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.08.004DOI Listing
September 2018
15 Reads

In vivo identification of novel TGIF2LX target genes in colorectal adenocarcinoma using the cDNA-AFLP method.

Arab J Gastroenterol 2018 Jun 28;19(2):65-70. Epub 2018 Jun 28.

Department of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Background And Study Aims: Homeobox-containing genes are composed of a group of regulatory genes encoding transcription factors involved in the control of developmental processes. The homeodomain proteins could activate or repress the expression of downstream target genes. This study was conducted to in vivo identify the potential target gene(s) of TGIF2LX in colorectal adenocarcinoma. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.05.001DOI Listing
June 2018
20 Reads

Treatment of PPI-resistant gastro-oesophageal reflux: A systematic review.

Arab J Gastroenterol 2018 Jun 20;19(2):51-55. Epub 2018 Jun 20.

Department of Surgical Sciences, "Sapienza" University of Rome, Italy. Electronic address:

Background And Study Aims: Several studies have demonstrated the superiority of proton-pump inhibitors (PPIs) in resolving erosive gastro-oesophageal reflux disease (GORD). However, this first line of treatment can fail to control symptoms in around 30% of cases, especially in the presence of non-erosive GORD. In situations where the first line of treatment fails, there is a lack of concordance regarding the best strategy to apply. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16871979183002
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http://dx.doi.org/10.1016/j.ajg.2018.02.007DOI Listing
June 2018
1 Read

The gut microbiome and irritable bowel syndrome: State of art review.

Arab J Gastroenterol 2018 Sep 20;19(3):136-141. Epub 2018 Jun 20.

Johns Hopkins University School of Medicine, Division of Gastroenterology and Hepatology, Baltimore, MD, 21287 United States.

Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal tract, the physiology of which is not very well understood. There are multiple factors and pathways involved in pathogenesis of this entity. Among all, dysmotility, dysregulation of the brain-gut axis, altered intestinal microbiota and visceral hypersensitivity play a major role. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.02.008DOI Listing
September 2018
2 Reads

Psychiatric and functional neuroimaging abnormalities in chronic hepatitis C virus patients: Is vasculitis a contributing factor?

Arab J Gastroenterol 2018 Jun 20;19(2):71-75. Epub 2018 Jun 20.

Rheumatology and Rehabilitation Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Background And Study Aims: Central nervous system (CNS) involvement in hepatitis C virus (HCV) infection has different facets such as anxiety, depression, cognitive impairment and vasculitis. We were interested in detecting subclinical CNS involvement in chronic HCV infected subjects with and without systemic vasculitis.

Patients And Methods: Nineteen patients (15 females and 4 males) with chronic HCV infection (mean age 46. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.06.003DOI Listing
June 2018
7 Reads

Rifaximin versus metronidazole in management of acute episode of hepatic encephalopathy: An open labeled randomized clinical trial.

Arab J Gastroenterol 2018 Jun 20;19(2):76-79. Epub 2018 Jun 20.

Department of Tropical Medicine and Gastroenterology, Assiut University Hospital, Assiut 71515 Egypt.

Background And Study Aims: Many regimens are tried in managing overt hepatic encephalopathy (HE). We investigated the efficacy of rifaximin versus metronidazole in management of an acute episode of HE on top of cirrhosis.

Patients And Methods: An open label prospective controlled trial was conducted on patients with an acute episode of HE on top of cirrhosis who were randomly divided into metronidazole-group (M-group) and rifaximin-group (R-group) with 60 patients in each. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.06.001DOI Listing
June 2018
20 Reads

Hepatitis C virus antibodies are absent among high risk group of health care workers in Damascus Hospital.

Arab J Gastroenterol 2018 Jun 20;19(2):80-83. Epub 2018 Jun 20.

Department of Internal Medicine, Faculty of Medicine, Syrian Private University, Damascus, Syria.

Background And Study Aims: Liver disease caused by hepatitis C virus (HCV) is one of the most serious health issues worldwide. The prevalence of HCV among health care workers (HCWs) is higher than normal population. Our aim is to determine the seroprevalence of HCV among this high-risk group in Damascus Hospital, Syria in 2016. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.02.012DOI Listing
June 2018
5 Reads

Acute lower gastrointestinal bleeding in Sudanese patients: a study on 301 patients in a specialized centre.

Arab J Gastroenterol 2018 Jun 7;19(2):84-87. Epub 2018 Jun 7.

Faculty of Medicine, Omdurman Islamic University, Department of GI Surgery, Ibn Sina Specialized Hospital, Khartoum, Sudan.

Background And Study Aims: Lower gastrointestinal bleeding originates from a site distal to the ligament of Treitz. It can present as an acute life-threatening or chronicbleeding. It is common among older patients and those with comorbidity. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.03.001DOI Listing
June 2018
26 Reads

Successful conservative treatment of type 3 injury (ductal injury) developing after ERCP.

Arab J Gastroenterol 2018 Jun 31;19(2):88-90. Epub 2018 May 31.

Department of Gastroenterology, Gulhane Military Medical Faculty, Ankara, Turkey.

Although endoscopic retrograde cholangio-pancreatography (ERCP) is considered a safe procedure, it is associated with complications such as pancreatitis, bleeding and perforation of the bile duct, pancreatic duct and duodenum. In recent years, successful conservative treatment in selected patients with complications have increased. We present a case with successful conservative treatment of rare injury (type 3) developing after ERCP. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.02.005DOI Listing

Impact of Franseen needle on rapid onsite evaluation and histological examination following endoscopic ultrasonography-guided tissue acquisition in patients with splenic malignant lymphoma.

Arab J Gastroenterol 2018 Jun 30;19(2):91-95. Epub 2018 May 30.

Pathology Division, University of Miyazaki Hospital, Japan.

Rapid onsite evaluation (ROSE) following endoscopic ultrasonography (EUS)-guided fine-needle aspiration contributes to the establishment of a diagnosis for various organs. Newly designed three-plane symmetric needles for EUS-guided fine-needle biopsy (EUS-FNB), such as the Franseen needle, have been developed to enable histological core tissue acquisition. However, EUS-guided tissue acquisition for hypervascular splenic lesions remains challenging. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.03.004DOI Listing
June 2018
1 Read

Oxidative stress is bane in chronic liver diseases: Clinical and experimental perspective.

Arab J Gastroenterol 2018 Jun 28;19(2):56-64. Epub 2018 May 28.

Department of Pharmacology, Saveetha Dental College, Saveetha Institue of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu-600 077, India. Electronic address:

Oxidative stress plays an important role in the pathogenesis of various chronic liver diseases (CLD) and increasing evidence have confirmed the contributory role of oxidative stress in the pathogenesis of drugs and chemical-induced CLD. Chronic liver injury is manifested as necrosis, cholestasis, fibrosis, and cirrhosis. Chronic administration of anti-tubercular, anti-retroviral, immunosuppressive drugs is reported to induce free radical generation during their biotransformation in the liver. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.03.002DOI Listing
June 2018
1 Read

Globular amyloidosis of the colon.

Arab J Gastroenterol 2018 Jun 24;19(2):96-99. Epub 2018 May 24.

Department of Surgical Patholology, Hospital Clínico San Carlos, Madrid, Spain.

Gastrointestinal involvement is frequent in systemic amyloidosis. However, amyloidosis can rarely be confined to the gastrointestinal tract or appear as a tumour mass. There have been few reports describing amyloid globular deposits in a variety of locations, as opposed to the usual linear ones. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16871979183004
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http://dx.doi.org/10.1016/j.ajg.2018.03.003DOI Listing
June 2018
1 Read

A note from the Editor's desk.

Authors:

Arab J Gastroenterol 2018 Mar;19(1):iv

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http://dx.doi.org/10.1016/S1687-1979(18)30031-5DOI Listing

Dendritic cell-based cancer immunotherapy for pancreatic cancer.

Arab J Gastroenterol 2018 Mar 8;19(1):1-6. Epub 2018 Mar 8.

Laboratory of Nuclear and Radiation Damage, The General Hospital of The PLA Rocket Force, Beijing 100088, China. Electronic address:

Pancreatic cancer (PC) is a lethal disease and remains one of the most resistant cancers to traditional therapies. New therapeutic modalities are urgently needed, particularly immunotherapy, which has shown promise in numerous animal model studies. Dendritic cell (DC)-based immunotherapy has been used in clinical trials for various cancers, including PC, because DCs are the most potent antigen-presenting cell (APC), which are capable of priming naive T cells and stimulating memory T cells to generate antigen-specific responses. Read More

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http://dx.doi.org/10.1016/j.ajg.2017.05.013DOI Listing
March 2018
5 Reads

EUS of pancreatic ascariasis.

Arab J Gastroenterol 2018 Mar 6;19(1):47-48. Epub 2018 Mar 6.

Department of Gastroenterology, Jaswant Rai Speciality Hospital, Saket, Meerut 250 001, Uttar Pradesh, India.

Ascaris is a common cause of acute pancreatitis in developing countries. The mechanism of ascariasis induced acute pancreatitis include obstruction of papilla of Vater, invasion of common bile duct, or pancreatic duct (PD). PD ascariasis is a rare diagnosis. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.02.011DOI Listing
March 2018
3 Reads

Helicobacter pylori infection in Egypt; a very common disease with low evidence based clinical practice.

Arab J Gastroenterol 2018 03 6;19(1):49. Epub 2018 Mar 6.

Endemic Gastroenterology and Hepatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

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http://dx.doi.org/10.1016/j.ajg.2018.02.009DOI Listing
March 2018
7 Reads

Copper concentrations in Egyptian infants with cholestasis: A single center study.

Arab J Gastroenterol 2018 Mar 6;19(1):21-25. Epub 2018 Mar 6.

Department of Paediatrics, Cairo University, Cairo, Egypt.

Background And Study Aims: Hepatobiliary cholestatic disorders produce excess copper (Cu) retention in the liver, which is toxic and may cause hepatitis, fulminant hepatic failure, cirrhosis and death. In this study, we measured hepatic Cu and tested its correlation with serum Cu (S. Cu) and serum ceruloplasmin (S. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.02.010DOI Listing
March 2018
3 Reads

"Post-cut": An endoscopic technique for managing impacted biliary stone within an entrapped extraction basket.

Arab J Gastroenterol 2018 Mar 5;19(1):37-41. Epub 2018 Mar 5.

Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China. Electronic address:

Background And Study Aims: Ampullary impaction of an entrapped stone-basket complex is not an infrequent yet challenging event during endoscopic retrograde cholangiopancreatography (ERCP). The aim of this study is to evaluate the feasibility, safety, and efficacy of "post-cut" for the management of such scenarios.

Patients And Methods: Patients with impacted biliary stone with an entrapped basket during ERCP at West China Hospital, Chengdu, China, from October 2004 to August 2014 were included in this retrospective study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16871979183001
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http://dx.doi.org/10.1016/j.ajg.2018.02.006DOI Listing
March 2018
8 Reads

Successful replacement of a metallic hepaticogastrostomy stent dislocated during endoscopic retrograde cholangiography.

Arab J Gastroenterol 2018 Mar 3;19(1):42-44. Epub 2018 Mar 3.

Division of Endoscdopy, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka 411-8777, Japan.

In the present case with lower bile duct cancer, an endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) was placed because of repeated obstructions of biliary metallic stent. However, when the HGS was occluded, transpapillary duodenoscopic procedure was again required. During this transpapillary procedure, including biliary balloon cleaning and metallic stent deployment, the HGS stent was dislocated into the stomach. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.02.003DOI Listing
March 2018
3 Reads

Determinants of survival following hepatocellular carcinoma in Egyptian patients with untreated chronic HCV infection in the pre-DAA era.

Arab J Gastroenterol 2018 Mar 3;19(1):26-32. Epub 2018 Mar 3.

The Kirby Institute, UNSW Sydney, Sydney, Australia.

Background And Study Aims: In this study we assessed rates and determinants of survival in people with untreated chronic HCV infection and hepatocellular carcinoma (HCC) in an Egyptian liver clinic setting.

Patients And Methods: This is a prospective cohort study of patients diagnosed with HCV-related HCC and undergoing HCC management at a national liver centre in Egypt in 2013-2014 and with a follow-up through 2016.

Results: A total of 345 patients diagnosed with HCV-related liver cirrhosis complicated by HCC were included. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.02.004DOI Listing
March 2018
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The prevalence of occult hepatitis B in chronic hepatitis C patients treated with interferon-based antiviral therapy.

Arab J Gastroenterol 2018 Mar 2;19(1):33-36. Epub 2018 Mar 2.

Department of Infection Disease and Clinical Microbiology, Mustafa Kemal University School of Medicine, Hatay, Turkey.

Background And Study Aims: Occult hepatitis B infection (OBI) is known to be mostly prevalent in chronic hepatitis C (CHC) patients and OBI reactivation might be life-threatening in patients undergoing interferon (IFN)-free direct acting antiviral (DAA) therapy. As previous studies have revealed a relationship between OBI and non-response to IFN-based antiviral therapy, the aim of the current study was to determine if there was a higher prevalence of OBI in IFN non-responders than responders.

Patients And Methods: This retrospective cross-sectional study was conducted in CHC patients who had previously received IFN-based antiviral therapy. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.02.001DOI Listing
March 2018
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