4,060 results match your criteria Aquatic Toxicology[Journal]


Lead toxicity in seawater teleosts: A morphofunctional and ultrastructural study on the gills of the Ornate wrasse (Thalassoma pavo L.).

Aquat Toxicol 2019 Apr 12;211:193-201. Epub 2019 Apr 12.

Department of Biology, Ecology and Earth Science, University of Calabria, Via P. Bucci 4/B, Rende, Cosenza, 87036, Italy. Electronic address:

Lead is one of the most alarming toxic pollutants for the environment due to its acute toxicity and high bioaccumulation tendency. Despite legislative efforts, world lead production has more than doubled since the early 1970s to 2016. Due to extensive exploitation and human activity, the coastal and estuarine regions belong to marine environments that are mostly and more rapidly deteriorated by pollutants including lead. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.04.009DOI Listing
April 2019
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Ecotoxicological effects of lanthanum in Mytilus galloprovincialis: Biochemical and histopathological impacts.

Aquat Toxicol 2019 Mar 25;211:181-192. Epub 2019 Mar 25.

Departamento de Biologia & CESAM, Universidade de Aveiro, 3810-193 Aveiro, Portugal. Electronic address:

Inappropriate processing and disposal of electronic waste contributes to the contamination of aquatic systems by various types of pollutants such as the rare-earth elements (REE) in which lanthanum (La) is included. Knowledge on the toxicity of these elements in marine organisms is still scarce when compared to other metals such as mercury (Hg) and arsenic (As). Therefore, this study aims to assess the toxicity of La on the mussel Mytilus galloprovincialis, considered a good bioindicator of aquatic pollution, through the analysis of metabolic, oxidative stress, neurotoxicity and histopathological markers. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.017DOI Listing
March 2019
2 Reads

Host-parasite interaction as a toxicity test endpoint using asymmetrical exposures.

Aquat Toxicol 2019 Apr 8;211:173-180. Epub 2019 Apr 8.

University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech Republic.

Interspecific relationships frequently determine the effect a pollutant can have on an organism, and this is especially true in closely interacting species such as hosts and parasites. The high spatial and temporal variability of contaminant concentrations combined with the movement of aquatic biota can further influence the consequences that are associated with contamination. We used a full factorial design for the exposed and unexposed partners of the relationship between the parasitic larvae (glochidia) of the European freshwater mussel (Anodonta anatina) and its host fish (Squalius cephalus) to identify the sources of variation in the sublethal endpoints of species interaction (the intensity of parasite attachment, the spatial position of glochidia on the host body, and encapsulation success). Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.04.006DOI Listing
April 2019
2 Reads

Influence of light intensity on cadmium uptake and toxicity in the cyanobacteria Synechocystis sp. PCC6803.

Aquat Toxicol 2019 Mar 25;211:163-172. Epub 2019 Mar 25.

College of Life Sciences, Central China Normal University, Wuhan, 430079, Hubei, PR China. Electronic address:

The mechanisms of cadmium toxicity to cyanobacterial photosynthesis have been extensively studied, but the response mechanisms to combinations of different cadmium concentrations and different light intensities are not yet well understood. The two principal objectives of the present work were to: 1) study the short term (5 h) toxic effects of cadmium on Synechocystis PCC6803 under three different culturing light intensity conditions; and, 2) investigate the effects of light history on Cd toxicity to Synechocystis. The maximal (Ф) and operational (Ф') photosystem II quantum yields, photosystem I quantum yield [Y (I)], cyclic electron flow, relative photochemical quenching (qPrel), relative non-photochemical quenching (qNrel), relative unquenched fluorescence (UQFrel), pigment contents, and cadmium uptake were evaluated when Synechocystis cells were treated with cadmium for 5 h under three different light conditions. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.016DOI Listing
March 2019
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Toxicity of binary mixtures of pesticides to the marine microalgae Tisochrysis lutea and Skeletonema marinoi: Substance interactions and physiological impacts.

Aquat Toxicol 2019 Apr 6;211:148-162. Epub 2019 Apr 6.

Ifremer, Laboratoire d'Écotoxicologie, rue de l'île d'Yeu, BP 21105, F-44311, Nantes cedex 03, France.

This study screened binary mixtures of pesticides for potential synergistic interaction effects on growth of the marine microalgae Tisochrysis lutea and Skeletonema marinoi. It also examined the single and combined effects of three of the most toxic substances on microalgal physiology. Single substances were first tested on each microalgal species to determine their respective EC and concentration-response relationships. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.015DOI Listing

Polyphenols obtained from Didymosphenia geminata (Lyngbye) Schmith altered the viability and proliferation of salmonids cells lines SHK-1 and CHSE-214.

Aquat Toxicol 2019 Apr 1;211:141-147. Epub 2019 Apr 1.

Laboratorio Biología Celular y Molecular Aplicada, Facultad de Ciencias, Universidad Mayor, Temuco, Chile. Electronic address:

Didymosphenia geminata (Lyngbye) Schmidt, also referred to as Didymo, is an invasive diatom that forms nuisance mats. Since it was first reported in our country in approximately 2010, Didymo has expanded and colonized different rivers in the Zona Austral region of Chile. Its biology and effects on ecosystems are still being studied because Didymo is an invasive algal mat that forms in a range of systems from oligotrophic austral rivers to more subtropical systems. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0166445X193005
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http://dx.doi.org/10.1016/j.aquatox.2019.03.022DOI Listing
April 2019
3 Reads

Water-soluble fraction of crude oil affects variability and has transgenerational effects in Daphnia magna.

Aquat Toxicol 2019 Apr 6;211:137-140. Epub 2019 Apr 6.

Department of Biology, University of Turku, FI-20014 Turku, Finland. Electronic address:

The importance of interindividual variability in environmental responses has been little studied, although the available information suggests that, e.g., changes in environmental temperature may be associated with changes in variability. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.04.004DOI Listing
April 2019
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Copper caused reproductive endocrine disruption in zebrafish (Danio rerio).

Aquat Toxicol 2019 Apr 4;211:124-136. Epub 2019 Apr 4.

SCNU Environmental Research Institute, Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety & MOE Key Laboratory of Environmental Theoretical Chemistry, South China Normal University, Guangzhou, 510006, China. Electronic address:

Cu in surface waters has been demonstrated to affect aquatic animals at ecologically relevant concentrations. However, its effects on reproductive endocrine system and the underlying toxicological mechanisms are largely unknown. In this study, zebrafish (Danio rerio) were exposed to 0, 10, 20, 40 μg/L of Cu for 30 days. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.04.003DOI Listing

Parental exposure to tebuconazole causes thyroid endocrine disruption in zebrafish and developmental toxicity in offspring.

Aquat Toxicol 2019 Apr 3;211:116-123. Epub 2019 Apr 3.

Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou 310058, PR China.

Azole fungicides are one class of the most extensively applied current-use pesticides. Tebuconazole is a common azole fungicide that has been frequently detected in aquatic ecosystems, thus raising concerns about its ecological safety. However, adverse effects of tebuconazole remain largely unknown, especially with regard to endocrine function in aquatic organisms. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.04.002DOI Listing
April 2019
2 Reads
3.451 Impact Factor

Biochemical and molecular responses of cyprinids in two Mediterranean lacustrine ecosystems: Opportunities for ecological assessment and biomonitoring.

Aquat Toxicol 2019 Apr 1;211:105-115. Epub 2019 Apr 1.

Laboratory of Ichthyology, Department of Zoology, School of Biology, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.

Lacustrine ecosystems have been altered by accelerating pollution, excessive nutrient and organic load, water abstraction, and are susceptible to climate change. Hence, suggesting sensitive and reliable biomarkers for early assessments of their status is of urgent need. In this study, two freshwater commercial fish species, Cyprinus carpio (carp) and Carassius gibelio (prussian carp) from two lakes (i. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.021DOI Listing
April 2019
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Impact of salt-contaminated freshwater on osmoregulation and tracheal gill function in nymphs of the mayfly Hexagenia rigida.

Aquat Toxicol 2019 Mar 27;211:92-104. Epub 2019 Mar 27.

Department of Biology, York University, Toronto, ON, M3J 1P3, Canada. Electronic address:

The impact of freshwater (FW) salinization on osmoregulation as well as tracheal gill morphology and function was examined in nymphs of the mayfly Hexagenia rigida following exposure to salt contaminated water (SCW, 7.25 g/l NaCl) for a 7-day period. Ionoregulatory homeostasis was perturbed in SCW exposed H. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.019DOI Listing

Effect of flavonoids isolated from Tridax procumbens on the growth and toxin production of Microcystis aeruginos.

Aquat Toxicol 2019 Apr 1;211:81-91. Epub 2019 Apr 1.

São Paulo State University (UNESP), School of Sciences, Humanities and Languages Assis, Department of Biotechnology, Laboratory of Herbal Medicine and Natural Products, Avenida Dom Antônio 2100, CEP: 19806-900, Assis, São Paulo, Brazil; São Paulo State University (UNESP), Institute of Chemistry, Rua Prof. Francisco Degni 55, CEP: 14800-060, Araraquara, São Paulo, Brazil. Electronic address:

The excessive proliferation of toxin producing cyanobacteria constitutes a significant health risk to the environment and humans. This is due to the contamination of potable water and accumulation of cyanotoxins in plant and animal tissues. As a means of controlling bloom forming cyanobacteria, secondary metabolites with pro-oxidative activities from plants are used to treat water bodies contaminated with cyanobacterial blooms and their associated toxins. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.011DOI Listing
April 2019
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Assessment of oxidative stress of paracetamol to Daphnia magna via determination of Nrf1 and genes related to antioxidant system.

Aquat Toxicol 2019 Mar 28;211:73-80. Epub 2019 Mar 28.

Department of Ecology, Jinan University, Guangzhou, 510632, China; Key Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, Jinan University, Guangzhou, 510632, China. Electronic address:

Paracetamol (APAP) is one of the most widely used anti-inflammatory and analgesic drugs in human being health care and has been universally detected in various aquatic environments. However, its potential adverse effects and toxic mechanisms on freshwater invertebrates still remain unclear. In the present study, the effects of APAP on the expressions of Nrf1 and the antioxidant related genes including GCLC, GST, GPX, CAT, TRX, TrxR and Prx1 in Daphnia magna (D. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.014DOI Listing
March 2019
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Oxidative stress response of caddisfly Stenopsyche marmorata larvae to abrupt hypoxia-normoxia shift.

Aquat Toxicol 2019 Apr 2;211:66-72. Epub 2019 Apr 2.

Department of Civil, Architectural and Environmental Engineering, Ibaraki University, Nakanarusawa 4-12-1, Hitachi, Ibaraki, 316-8511, Japan.

Natural and anthropogenic effects cause low dissolved oxygen conditions (hypoxia) and subsequent reoxygenated conditions (normoxia) in river systems. However, oxidative stress responses to hypoxia-normoxia shift in aquatic insects are still poorly understood. Here, we exposed caddisfly Stenopsyche marmorata larvae to 30-min hypoxic followed by 1-d normoxic exposure, with experiments being repeated at 14 °C (Exp. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.04.001DOI Listing

Comparative studies of the response of sensitive and tolerant submerged macrophytes to high ammonium concentration stress.

Aquat Toxicol 2019 Mar 29;211:57-65. Epub 2019 Mar 29.

Zhengzhou Yuanzhihe Environmental Protection Technology Co., Ltd., Zhengzhou, Henan, 450000, China.

Three submerged macrophytes, Ceratophyllum demersum (CD), Myriophyllum spicatum (MS) and Myriophyllum aquaticum (MA), were treated with various concentrations of ammonia for different lengths of time. Ammonium ions (NH) in the medium severely inhibited plant growth and led to a reduction in total chlorophyll (chl a and b) in CD and MS. The addition of ammonia significantly decreased the soluble protein content and increased the free amino acid content of CD and MS in treatments with high concentrations of NH, but MA showed no significant physiological response. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.020DOI Listing

Exposure to a nanosilver-enabled consumer product results in similar accumulation and toxicity of silver nanoparticles in the marine mussel Mytilus galloprovincialis.

Aquat Toxicol 2019 Mar 28;211:46-56. Epub 2019 Mar 28.

Department of Physical, Earth and Environmental Sciences, University of Siena, via Mattioli 4, Siena, Italy.

The incorporation of silver nanoparticles (AgNPs) in commercial products is increasing rapidly. The consequent release of AgNPs into domestic and industrial wastewater raises environmental concerns due to their anti-microbial properties and toxicity to non-target aquatic organisms. The aim of the present study was to investigate the effects of nanArgen™ (Nanotek S. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.018DOI Listing
March 2019
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Whether warming magnifies the toxicity of a pesticide is strongly dependent on the concentration and the null model.

Aquat Toxicol 2019 Mar 20;211:38-45. Epub 2019 Mar 20.

Laboratory of Evolutionary Stress Ecology and Ecotoxicology, University of Leuven, Belgium.

How global warming changes the toxicity of contaminants is a research priority at the intersection of global change biology and ecotoxicology. While many pesticides are more toxic at higher temperatures this is not always detected. We studied whether deviations from this general pattern can be explained by concentration-dependent interaction effects and by testing the interaction against the inappropriate null model. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.010DOI Listing

Does intraspecific variability matter in ecological risk assessment? Investigation of genotypic variations in three macrophyte species exposed to copper.

Aquat Toxicol 2019 Mar 19;211:29-37. Epub 2019 Mar 19.

ECOLAB, Université de Toulouse, CNRS, INPT, UPS, France.

To limit anthropogenic impact on ecosystems, regulations have been implemented along with global awareness that human activities are harmful to the environment. Ecological risk assessment (ERA) is the main procedure which allows to assess potential impacts of stressors on the environment as a result of human activities. ERA is typically implemented through different steps of laboratory testing. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.012DOI Listing
March 2019
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The relative importance of waterborne and dietborne As exposure on survival and growth of juvenile fathead minnows.

Aquat Toxicol 2019 Mar 8;211:18-28. Epub 2019 Mar 8.

U.S. Environmental Protection Agency, Mid-Continent Ecology Division, 6201 Congdon Blvd., Duluth, MN, 55804, USA.

The survival and growth of juvenile fathead minnows were investigated at various combinations of waterborne exposure to arsenate and of dietborne exposure to oligochaete worms which had been exposed to inorganic arsenic. Previous work with rainbow trout established that dietborne arsenic can reduce fish growth at environmentally relevant concentrations and could be more important than waterborne exposures. This was found to be less true for fathead minnows, which were less sensitive to dietborne exposures than rainbow trout, while being as or more sensitive to waterborne exposures. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.008DOI Listing
March 2019
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Effect of copper nanoparticles and ions on spermatozoa motility of sea trout (Salmo trutta m. Trutta L.).

Aquat Toxicol 2019 Mar 20;211:11-17. Epub 2019 Mar 20.

Department of Hydrobiology and General Zoology, Faculty of Biology, University of Szczecin, Szczecin, Poland.

Nanoproducts are being increasingly used in various industrial products, leading to a greater risk of water pollution through their discharge into environment as production byproducts. Increased levels of environmental pollution with nanoproducts pose a threat to all living organisms. Nanopollutants may have toxic effects on gametes and fertilization process in species with external fertilization, thereby reducing effectiveness of reproduction or greatly impairing it. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0166445X183076
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http://dx.doi.org/10.1016/j.aquatox.2019.03.013DOI Listing
March 2019
3 Reads

The osmotic effect of hyper-saline hydraulic fracturing fluid on rainbow trout, Oncorhynchus mykiss.

Aquat Toxicol 2019 Mar 14;211:1-10. Epub 2019 Mar 14.

Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada; National Institute for Nanotechnology, Edmonton, Alberta, Canada.

Flowback and produced water (FPW) is a complex, often brackish, solution formed during the process of hydraulic fracturing. Despite recent findings on the short-term toxicity of FPW on aquatic biota, longer-term impacts of FPW on fish have not yet been investigated and the mechanisms of chronic effects remain unknown. The aim of the present study was to observe the effect of a diluted FPW on ionoregulatory endpoints in the rainbow trout Oncorhynchus mykiss, following a 28-d sub-chronic exposure. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.009DOI Listing

Effects of copper on the dinoflagellate Alexandrium minutum and its allelochemical potency.

Aquat Toxicol 2019 May 8;210:251-261. Epub 2019 Mar 8.

School of Chemistry, University of Wollongong, NSW, 2522, Australia.

The dinoflagellate Alexandrium minutum produces toxic compounds, including paralytic shellfish toxins, but also some unknown extracellular toxins. Although copper (Cu) is an essential element, it can impair microalgal physiology and increase their toxic potency. This study investigated the effect of different concentrations of dissolved Cu (7 nM, 79 nM and 164 nM) on A. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.006DOI Listing
May 2019
1 Read

Toxic effects of oxine-copper on development and behavior in the embryo-larval stages of zebrafish.

Aquat Toxicol 2019 May 27;210:242-250. Epub 2019 Feb 27.

Jiangxi Engineering Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases, Jiangxi Key Laboratory of Developmental Biology of Organs, Ji'an, Jiangxi, China; Center for Developmental Biology of Jinggangshan University, College of Life Sciences, Jinggangshan University, Ji'an, Jiangxi, China. Electronic address:

Oxine-copper (OxCu) is generally used as an agricultural pesticide and induces harmful effects on ecosystems. In this study, zebrafish was used to assess the aquatic toxicity of OxCu. To detect the effects on development, embryos of 6 h post-fertilization (hpf) were exposed to 10 μg/L, 20 μg/L, 40 μg/L OxCu for 18 h; meanwhile, to evaluate the effects on the behavior, larval fish at 6 days post-fertilization (dpf) were exposed to the same concentrations for 24 h. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.020DOI Listing

The effects of arsenic speciation on accumulation and toxicity of dietborne arsenic exposures to rainbow trout.

Aquat Toxicol 2019 May 5;210:227-241. Epub 2019 Mar 5.

U.S. Environmental Protection Agency, Mid-Continent Ecology Division, 6201 Congdon Blvd., Duluth, MN 55804, USA.

The effects on juvenile rainbow trout survival, growth, food consumption, and food conversion efficiency from dietborne exposures to inorganic arsenic (arsenite, arsenate) and to the organoarsenicals monomethylarsonate (MMA), dimethylarsinate (DMA), and arsenobetaine (AsB) were investigated in two experiments: (1) a 28-d exposure using live diets of oligochaete worms separately exposed via water to these five arsenic compounds and (2) a 56-d exposure using pellet diets prepared from commercial fish food to which arsenite, MMA, or DMA were added. In the live diet experiment, the degree to which worms could be contaminated with the organoarsenicals was limited by toxicity to the worms and other experimental constraints, so that their toxicity relative to inorganic arsenic could not be fully established, but AsB was concluded to have low toxicity, consistent with published results for mammals. For the pellet diet experiment, MMA and DMA were found to be at least an order of magnitude less toxic than inorganic As on the basis of concentration in the diet, as well as much less toxic on the basis of accumulation in the fish. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.001DOI Listing
May 2019
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Developmental and epigenetic effects of Roundup and glyphosate exposure on Japanese medaka (Oryzias latipes).

Aquat Toxicol 2019 May 7;210:215-226. Epub 2019 Mar 7.

Department of Biology, University of North Carolina Greensboro, Greensboro, NC, 27412, United States. Electronic address:

Roundup and other glyphosate-based herbicides are the most commonly used herbicides in the world, yet their effects on developing fish embryos are not clearly understood. The present study, therefore, examined developmental teratogenic effects and adult-onset reproductive effects of exposure to environmentally relevant concentrations of glyphosate and Roundup in Japanese medaka fish (Oryzias latipes). Hd-rR strain medaka embryos were exposed to 0. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.005DOI Listing

Histopathological and ultrastructural indices for the assessment of glyphosate-based herbicide cytotoxicity in decapod crustacean hepatopancreas.

Aquat Toxicol 2019 May 8;210:207-214. Epub 2019 Mar 8.

Departamento de Biologia Celular, Embriologia e Genética, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil. Electronic address:

Glyphosate-based herbicides (GBH), including Roundup, are the most widely used pesticides in the world. Glyphosate residues have been detected in surface and groundwater, in food, and in human blood and urine. The effects of this herbicide on different levels of biological organization are an important concern that needs to be investigated. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.007DOI Listing
May 2019
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Fullerene C nanomaterial induced oxidative imbalance in gonads of the freshwater fish, Anabas testudineus (Bloch, 1792).

Authors:
N Sumi K C Chitra

Aquat Toxicol 2019 May 5;210:196-206. Epub 2019 Mar 5.

Endocrinology and Toxicology Laboratory, Department of Zoology, University of Calicut, Malappuram District, Kerala, 673 635, India. Electronic address:

The engineered carbon nanomaterial, fullerene C, with unique physicochemical properties, released into the aquatic environment is known to formulate high risk factor for the aquatic life. The present study was aimed to investigate fullerene C induced oxidative imbalance in ovary and testis of the freshwater fish, Anabas testudineus. The median lethal concentration (96 h-LC) of fullerene C in Anabas testudineus was 50 mg/ L, and fish exposed to two sublethal concentrations i. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.003DOI Listing

Adverse effects, expression of defense-related genes, and oxidative stress-induced MAPK pathway in the benzo[α]pyrene-exposed rotifer Brachionus rotundiformis.

Aquat Toxicol 2019 May 6;210:188-195. Epub 2019 Mar 6.

Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea. Electronic address:

To examine the adverse effects of the benzo[α]pyrene (B[α]P), the monogonont rotifer Brachionus rotundiformis was exposed to various concentration of B[α]P (0 [control], 1, 10, and 100 μg/L) and measured life cycle parameters (e.g., mortality, fecundity [cumulated number of offspring], and lifespan), reactive oxygen species (ROS), antioxidant enzymatic activity of glutathione S-transferase (GST). Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.004DOI Listing
May 2019
1 Read
3.451 Impact Factor

Combined effects of nanoplastics and copper on the freshwater alga Raphidocelis subcapitata.

Aquat Toxicol 2019 May 28;210:179-187. Epub 2019 Feb 28.

Department of Physical, Earth and Environmental Sciences, University of Siena, Siena, Italy.

Nanoplastics are recognized as able to interact with other pollutants including heavy metals, and with natural organic matter, with implications for the potential risks to biota. We investigated the interaction of carboxylated polystyrene nanoparticles (PS-COOH NPs) with copper (Cu) and algal exudates (EPS) and how such interaction could affect Cu toxicity towards the freshwater microalga Raphidocelis subcapitata. PS-COOH NPs behavior in the presence of Cu and EPS was determined by dynamic light scattering (DLS), while PS-COOH NPs surface interaction with Cu ions and EPS was investigated by fluorimetric analysis. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.022DOI Listing
May 2019
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Seawater acidification increases copper toxicity: A multi-biomarker approach with a key marine invertebrate, the Pacific Oyster Crassostrea gigas.

Aquat Toxicol 2019 May 5;210:167-178. Epub 2019 Mar 5.

Muping Coastal Environmental Research Station, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, Shandong, 264117, PR China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, PR China; Key Laboratory of Coastal Biology and Biological Resources Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, Shandong, 264003, PR China. Electronic address:

Ocean acidification (OA) has been found to increase the release of free Cu in seawater. However, only a handful of studies have investigated the influence of OA on Cu accumulation and cellular toxicity in bivalve species. In this study, Pacific oysters, Crassostrea gigas, were exposed to 25 μg/L Cu at three pH levels (8. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.03.002DOI Listing
May 2019
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Effect of daily exposure to Pb-contaminated water on Salvinia biloba physiology and phytoremediation performance.

Aquat Toxicol 2019 May 27;210:158-166. Epub 2019 Feb 27.

Grupo de Biotecnología de Materiales y Medioambiente (BioTecMA), Fac. de Química e Ingeniería del Rosario, Pontificia Universidad Católica Argentina (UCA), Av. Pellegrini 3314 (2000), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Rosario, Argentina. Electronic address:

Lead (Pb) removal from water column was evaluated in batch experiments using naturally occurring Salvinia biloba Raddi (S. biloba) specimens collected from Middle Paraná River and exposed every 24 h to a fresh discharge of water contaminated with 2.65 ± 0. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.019DOI Listing
May 2019
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Life history and physiological responses of native and invasive brine shrimps exposed to zinc.

Aquat Toxicol 2019 May 1;210:148-157. Epub 2019 Mar 1.

Wetland Ecology Department, Estación Biológica de Doñana, EBD-CSIC, 41092 Seville, Spain; Instituto Universitario de Investigación Marina (INMAR), Campus de Excelencia Internacional/Global del Mar (CEI·MAR), Universidad de Cádiz, Av. República Saharaui s/n, 11510 Puerto Real (Cádiz), Spain.

Although a substantial amount of research exists on pollution and biological invasions, there is a paucity of understanding of how both factors interact. Most studies show that pollution favours the establishment of invasive species, but pollution may also promote local adaptation of native species and prevent the establishment of new incomers. However, evidence for this is extremely limited because most studies focus on successful invasions and very few on cases where an invasion has been resisted. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.023DOI Listing

Optical toxicity of triphenyl phosphate in zebrafish larvae.

Aquat Toxicol 2019 May 1;210:139-147. Epub 2019 Mar 1.

State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.

Triphenyl phosphate (TPhP) has been shown to cause developmental neurotoxicty. Considering the visual system is a sensitive target, in the present study, we investigated the potential toxicity of TPhP on the visual development and function in zebrafish larvae. Embryos were exposed to 0, 0. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.024DOI Listing
May 2019
1 Read

Stereoselective toxicity of metconazole to the antioxidant defenses and the photosynthesis system of Chlorella pyrenoidosa.

Aquat Toxicol 2019 May 25;210:129-138. Epub 2019 Feb 25.

Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West Road 2, Beijing, 100193, China; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Yuanmingyuan West Road 2, Beijing, 100193, China. Electronic address:

Metconazole (MEZ) is a broad-spectrum fungicide with four optical stereoisomers. Compared to traditional fungicides, it achieves better control effect at lower dosages. However, its toxicity to non-target organisms has rarely been investigated. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.017DOI Listing
May 2019
1 Read
3.451 Impact Factor

Oxidative stress potential of the herbicides bifenox and metribuzin in the microalgae Chlamydomonas reinhardtii.

Aquat Toxicol 2019 May 27;210:117-128. Epub 2019 Feb 27.

Norwegian Institute for Water Research, Gaustadalléen 21, 0349 Oslo, Norway; Centre for Environmental Radioactivity, Norwegian University of Life Sciences (NMBU), Post box 5003, N-1432 Ås, Norway.

The widespread presence of herbicides in the aquatic environment has raised awareness about the need to develop further in depth ecotoxicological risk assessments, more specifically on potential effects on photosynthetic organisms as microalgae. The majority of the information available regarding the toxicity of herbicides towards microalgae is related to traditional toxicological and regulatory-relevant endpoints such as growth inhibition, leaving a significant gap on knowledge regarding underlying interactions and damage to biological targets. In this context, this study aimed to supplement the general toxicity information of bifenox and metribuzin in the microalgae Chlamydomonas reinhardtii using a battery of selected high-throughput methods. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.021DOI Listing

Predicting the toxic effects of Cu and Cd on Chlamydomonas reinhardtii with a DEBtox model.

Aquat Toxicol 2019 May 27;210:106-116. Epub 2019 Feb 27.

Key Laboratory of Pollution Process and Environmental Criteria of Ministry of Education and Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China.

Predicting the sublethal effects of pollutants to aquatic organism is essential in realistic chemical risk assessment. However, only a few dynamics models for sublethal endpoints are available. Here, we investigated the toxic effects of the essential metal Cu and the nonessential metal Cd on Chlamydomonas reinhardtiiunder both single and combined exposure, compared the effectiveness of different effect endpoints as toxic effect factors, and developed a Dynamic Energy Budget toxicology (DEBtox) model to predict the sublethal effects of Cu and Cd on C. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.018DOI Listing

Immune response, MT and HSP70 gene expression, and bioaccumulation induced by lead exposure of the marine crab, Charybdis japonica.

Aquat Toxicol 2019 May 27;210:98-105. Epub 2019 Feb 27.

Jiangsu Key Laboratory of Marine Bioresources and Environment, Huaihai Institute of Technology, China. Electronic address:

In order to understand the mechanisms of the toxicity of lead (Pb) on invertebrates, the immunotoxic effects of Pb in the marine crab, Charybdis japonica, were evaluated in the present study. The crabs were exposed to 0.066, 0. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.013DOI Listing
May 2019
6 Reads

Variation in transcriptional responses to copper exposure across Daphnia pulex lineages.

Aquat Toxicol 2019 May 21;210:85-97. Epub 2019 Feb 21.

Department of Biology, McGill University, QC, H3A 1B1, Canada.

Copper pollution is pervasive in aquatic habitats and is particularly harmful to invertebrates sensitive to environmental changes such as Daphnia pulex. Mechanisms of toxicity and tolerance to copper are not well understood. We used RNA-sequencing to investigate these mechanisms in three genetically distinct D. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0166445X183091
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http://dx.doi.org/10.1016/j.aquatox.2019.02.016DOI Listing
May 2019
6 Reads

The genome of the freshwater water flea Daphnia magna: A potential use for freshwater molecular ecotoxicology.

Aquat Toxicol 2019 May 15;210:69-84. Epub 2019 Feb 15.

Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea. Electronic address:

The water flea Daphnia magna is a small planktonic cladoceran. D. magna has been used as a model species for ecotoxicology, as it is sensitive to environmental stressors and environmental changes. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.009DOI Listing
May 2019
5 Reads
3.451 Impact Factor

Changes in protein expression in mussels Mytilus galloprovincialis dietarily exposed to PVP/PEI coated silver nanoparticles at different seasons.

Aquat Toxicol 2019 May 18;210:56-68. Epub 2019 Feb 18.

CBET Research Group, Dept. Zoology and Animal Cell Biology, Faculty of Science and Technology and Research Centre for Experimental Marine Biology and Biotechnology PiE, University of the Basque Country UPV/EHU, Basque Country, Spain. Electronic address:

Potential toxic effects of Ag NPs ingested through the food web and depending on the season have not been addressed in marine bivalves. This work aimed to assess differences in protein expression in the digestive gland of female mussels after dietary exposure to Ag NPs in autumn and spring. Mussels were fed daily with microalgae previously exposed for 24 h to 10 μg/L of PVP/PEI coated 5 nm Ag NPs. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.010DOI Listing

The role of intraspecies variation in fish neurobehavioral and neuropharmacological phenotypes in aquatic models.

Aquat Toxicol 2019 May 20;210:44-55. Epub 2019 Feb 20.

School of Pharmacy, Southwest University, Chongqing, China; Scientific Research Institute of Physiology and Basic Medicine, Novosibirsk, Russia; The International Zebrafish Neuroscience Research Consortium (ZNRC), Slidell, LA, USA; Ural Federal University, Ekaterinburg, Russia; ZENEREI Research Center, Slidell, LA, USA; Laboratory of Biological Psychiatry, Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia; Institute of Experimental Medicine, Almazov National Medical Research Centre, Ministry of Healthcare of Russian Federation, St. Petersburg, Russia; Granov Russian Research Centre of Radiology and Surgical Technologies, Ministry of Healthcare of Russian Federation, St. Petersburg, Russia. Electronic address:

Intraspecies variation is common in both clinical and animal research of various brain disorders. Relatively well-studied in mammals, intraspecies variation in aquatic fish models and its role in their behavioral and pharmacological responses remain poorly understood. Like humans and mammals, fishes show high variance of behavioral and drug-evoked responses, modulated both genetically and environmentally. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.015DOI Listing
May 2019
3 Reads

Altered lipid homeostasis in a PCB-resistant Atlantic killifish (Fundulus heteroclitus) population from New Bedford Harbor, MA, U.S.A.

Aquat Toxicol 2019 May 18;210:30-43. Epub 2019 Feb 18.

Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA; Boston University Superfund Research Program, Boston, MA, USA.

Sentinel species such as the Atlantic killifish (Fundulus heteroclitus) living in urban waterways can be used as toxicological models to understand impacts of environmental metabolism disrupting compound (MDC) exposure on both wildlife and humans. Exposure to MDCs is associated with increased risk of metabolic syndrome, including impaired lipid and glucose homeostasis, adipogenesis, appetite control, and basal metabolism. MDCs are ubiquitous in the environment, including in aquatic environments. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.011DOI Listing

The impact of ocean acidification on the gonads of three key Antarctic benthic macroinvertebrates.

Aquat Toxicol 2019 May 18;210:19-29. Epub 2019 Feb 18.

Department of Earth, Environment and Life Sciences (DiSTAV), University of Genoa, Corso Europa 26, 16132, Genova, Italy. Electronic address:

CO atmospheric pressure is increasing since industrial revolution, leading to a lowering of the ocean surface water pH, a phenomenon known as ocean acidification, with several reported effects on individual species and cascading effects on marine ecosystems. Despite the great amount of literature on ocean acidification effects on calcifying organisms, the response of their reproductive system still remains poorly known. In the present study, we investigated the histopathological effects of low pH on the gonads of three key macroinvertebrates of the Terra Nova Bay (Ross Sea) littoral area: the sea urchin Sterechinus neumayeri, the sea star Odontaster validus and the scallop Adamussium colbecki. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.012DOI Listing
May 2019
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Waterborne pharmaceutical uptake and toxicity is modified by pH and dissolved organic carbon in zebrafish.

Aquat Toxicol 2019 May 14;210:11-18. Epub 2019 Feb 14.

Department of Biology, McMaster University, 1280 Main St. W., Hamilton, L8S 4K1, ON, Canada.

Human and veterinary pharmaceuticals have been observed in natural aquatic environments around the world, and many have been shown to impact fish health. Presently, we examined the influence of pH, dissolved organic carbon (DOC) and Na or Ca on the bioavailability and toxicity of waterborne pharmaceuticals in larval zebrafish. Drugs included sertraline (selective serotonin reuptake inhibitor; SSRI), fluoxetine (SSRI), diclofenac (nonsteroidal anti-inflammatory drug) and ethinyl estradiol (estrogen; EE). Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.008DOI Listing
May 2019
2 Reads

Sub-lethal doses of polybrominated diphenyl ethers affect some biomarkers involved in energy balance and cell cycle, via oxidative stress in the marine fish cell line SAF-1.

Aquat Toxicol 2019 May 19;210:1-10. Epub 2019 Feb 19.

University of Palermo, Dept of Earth and Marine Science DISTEM, Laboratory of Marine Biochemistry and Ecotoxicology, Via Barlotta 4, 91100, Trapani, Italy. Electronic address:

Polybrominated diphenyl ethers (PBDEs) are a class of persistent contaminants which are found all over the world in the marine environment. Sparus aurata fibroblast cell line (SAF-1) was exposed to increasing concentrations of PBDEs 47 and 99, until 72 h to evaluate the cytotoxicity, reactive oxygen species (ROS) production and the expression of some selected molecular markers related to cell cycle, cell signaling, energetic balance and oxidative stress (p53, erk-1, hif-1α and nrf-2), by real-time PCR. Furthermore, SAF-1 cells were exposed for 7 and 15 days to sub-lethal concentrations, in order to evaluate the response of some biomarkers by immunoblotting (p53, ERK-1, AMPK, HIF-1α and NRF-2). Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.014DOI Listing

Cisplatin exposure impairs ionocytes and hair cells in the skin of zebrafish embryos.

Aquat Toxicol 2019 Apr 13;209:168-177. Epub 2019 Feb 13.

Department of Life Science, School of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan. Electronic address:

This study aimed to assess the sublethal effects of a platinum-based compound, cisplatin, using a zebrafish model. Zebrafish embryos were incubated in different concentrations of cisplatin at 0-96 h post-fertilization. Using a non-invasive, scanning ion-selective electrode technique (SIET), we measured the functions of hair cells (Ca influx) and ionocytes ([H] gradients). Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.006DOI Listing
April 2019
3 Reads

Immunotoxicity of estrogen and nonylphenol on apoptosis and expression of ERs in goldfish macrophage: Opening new avenue for discovering the role of experimental model systems and sexes.

Aquat Toxicol 2019 Apr 13;209:159-167. Epub 2019 Feb 13.

Department of Fisheries, Faculty of Marine Natural resources, Khorramshahr University of Marine Science and Technology, P.O. Box 669, Khorramshahr, Iran. Electronic address:

The expression of estrogen receptors (ERs) and their roles in important cell processes such as apoptosis in the macrophages exposed to estrogen/xenoestrogen have remained a complex secret. This study focused on the expression of estrogen receptors (ERs) and the stimulation of apoptosis in the macrophages from the two sexes of goldfish (Carassius auratus) exposed to 17-βestradiol (E2) and nonylphenol (NP) under in vivo and in vitro conditions. For the in vivo experiment, fish were exposed to NP (10 M and 10 M) and E2 (10 M) for 24 days. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.007DOI Listing
April 2019
5 Reads
3.451 Impact Factor

Are magnetic and electromagnetic fields of anthropogenic origin potential threats to early life stages of fish?

Aquat Toxicol 2019 Apr 30;209:150-158. Epub 2019 Jan 30.

Department of Fisheries Oceanography and Marine Ecology, National Marine Fisheries Research Institute, Kołłątaja 1, 81-332 Gdynia, Poland.

The number of underwater cables transferring electric current in sea and freshwater environments is constantly increasing. As a result, the risk of negative effects of magnetic fields generated in the vicinity of those cables on fish eggs and larvae is also growing. This is especially the case for species that settle on the bottom for certain periods of time during early development. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.01.023DOI Listing

Waterborne copper is more toxic to the killifish Poecilia vivipara in elevated temperatures: Linking oxidative stress in the liver with reduced organismal thermal performance.

Aquat Toxicol 2019 Apr 7;209:142-149. Epub 2019 Feb 7.

Programa de Pós-Graduação em Ciências Fisiológicas, Instituto de Ciências Biológicas, Universidade Federal do Rio Grande, 96203-900, Rio Grande, RS, Brazil. Electronic address:

In this study, we measured the interactive effect of temperature (22 °C and 28 °C) and waterborne copper (Cu) contamination (9 μg/L and 20 μg/L) on the killifish Poecilia vivipara. Endpoints analyzed included parameters involved in Cu-accumulation, antioxidant capacity (antioxidant capacity against peroxyl radicals [ACAP] and total antioxidant capacity [TAC]), oxidative damage (lipid peroxidation [LPO]) and upper thermal tolerance (critical thermal maximum [CTMax]). Results show that Cu hepatic accumulation was elevated in 28 °C in comparison to 22 °C in both exposure groups. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.005DOI Listing
April 2019
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Parental exposure to tris(1,3-dichloro-2-propyl) phosphate results in thyroid endocrine disruption and inhibition of growth in zebrafish offspring.

Aquat Toxicol 2019 Apr 7;209:132-141. Epub 2019 Feb 7.

Key Laboratory of Preparation and Application of Environmental Friendly Materials, the Ministry of Education, Jilin Normal University, Siping, 136000, China.

Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a re-emerging environmental contaminant used as a suitable substitute for brominated flame retardants. The objective of this study was to evaluate the effects of TDCIPP on thyroid disruption and growth inhibition in zebrafish (Danio rerio) offspring after chronic parental exposure, and to examine the possible molecular mechanisms involved. When adult zebrafish (4 months old) were exposed to 5. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.004DOI Listing
April 2019
2 Reads