869 results match your criteria Applied health economics and health policy[Journal]


The Efficacy of Lockdown Against COVID-19: A Cross-Country Panel Analysis.

Appl Health Econ Health Policy 2020 Jun 3. Epub 2020 Jun 3.

Department of Mathematics, Computer Science, and Economics, University of Basilicata, Potenza, Italy.

Background: There has been much debate about the effectiveness of lockdown measures in containing COVID-19, and their appropriateness given the economic and social cost they entail. To the best of our knowledge, no existing contribution to the literature has attempted to gauge the effectiveness of lockdown measures over time in a longitudinal cross-country perspective.

Objectives: This paper aims to fill the gap in the literature by assessing, at an international level, the effect of lockdown measures (or the lack of such measures) on the numbers of new infections. Read More

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http://dx.doi.org/10.1007/s40258-020-00596-3DOI Listing

Availability and Variability of Consumer Prices for Lumbar Discectomy Across US Hospitals in 2018.

Appl Health Econ Health Policy 2020 Jun 3. Epub 2020 Jun 3.

Department of Neurological Surgery, University of Miami Miller School of Medicine, 1475 NW 12th St, 1st Floor, Miami, FL, 33136, USA.

Objective: To determine the availability and variability of consumer pricing data for an elective lumbar discectomy in the USA.

Methods: Hospital representatives were contacted via telephone, hospital websites, and state price-transparency websites. A total of 153 hospitals were contacted via telephone calls under the guise of a patient requesting a self-pay price for elective lumbar discectomy. Read More

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http://dx.doi.org/10.1007/s40258-020-00592-7DOI Listing

Factors Influencing the Cost-Effectiveness Outcomes of HPV Vaccination and Screening Interventions in Low-to-Middle-Income Countries (LMICs): A Systematic Review.

Appl Health Econ Health Policy 2020 May 29. Epub 2020 May 29.

Centre for Health Economics and Medicines Evaluation, Bangor University, Normal Site, Bangor, Gwynedd, LL57 2PZ, UK.

Background: Cervical cancer ranks fourth amongst the commonest malignancies worldwide and the second most prevalent cancer afflicting women in low-to-middle income countries (LMICs), hence, of great public health importance. LMICs are the most affected regions as evidenced by their high prevalence of the disease. Mortality associated with cervical neoplasms is preventable through the implementation of recommended preventive approaches. Read More

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http://dx.doi.org/10.1007/s40258-020-00576-7DOI Listing

Using a Formal Strategy of Priority Setting to Mitigate Austerity Effects Through Gains in Value: The Role of Program Budgeting and Marginal Analysis (PBMA) in the Brazilian Public Healthcare System.

Appl Health Econ Health Policy 2020 May 29. Epub 2020 May 29.

School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.

The fiscal regime implemented in Brazil with the constitutional amendment 95 (EC-95) of December 2016 froze primary expenditures for 20 years, including healthcare spending. Previous studies have estimated strong negative effects of this policy on the health of Brazilians. Although there has been a constant pressure to repeal EC-95, this policy is unlikely to be changed in the near future. Read More

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http://dx.doi.org/10.1007/s40258-020-00591-8DOI Listing

The Italian NHS: What Lessons to Draw from COVID-19?

Appl Health Econ Health Policy 2020 May 26. Epub 2020 May 26.

Institute of Clinical Trials and Methodology, University College London, London, UK.

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http://dx.doi.org/10.1007/s40258-020-00594-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247917PMC

Using Insights from Behavioral Economics to Mitigate the Spread of COVID-19.

Appl Health Econ Health Policy 2020 Jun;18(3):345-350

Research Center for Environmental Determinants of Health, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

The outbreak of 2019 coronavirus disease (COVID-19) has become a public health emergency of international concern. The number of COVID-infected individuals and related deaths continues to rise rapidly. Encouraging people to adopt and sustain preventive behaviors is a central focus of public health policies that seek to mitigate the spread of COVID-19. Read More

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http://dx.doi.org/10.1007/s40258-020-00595-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239690PMC

Effect of an Online Reimbursement Application System on Prescribing of Lidocaine 5% Medicated Plaster in the Republic of Ireland.

Appl Health Econ Health Policy 2020 May 20. Epub 2020 May 20.

Department of Pharmacology and Therapeutics, Trinity College Dublin, Trinity Centre for Health Sciences, St. James' Hospital, Dublin 8, Ireland.

Background: The lidocaine 5% medicated plaster, Versatis, has one therapeutic indication listed on the Summary of Product Characteristics-symptomatic relief of post-herpetic neuralgia (PHN) in adults. Increased expenditure on Versatis suggests that there is considerable off-label use. To support the appropriate use of Versatis, the Health Service Executive's Primary Care Reimbursement Service (PCRS) introduced a reimbursement application system for Versatis from 1 September 2017. Read More

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http://dx.doi.org/10.1007/s40258-020-00586-5DOI Listing

Economic Evaluation of Senshio (Ospemifene) for the Treatment of Vulvovaginal Atrophy in Scotland.

Appl Health Econ Health Policy 2020 May 11. Epub 2020 May 11.

Health Economics and Market Access, Shionogi B.V., 33 Kingsway, London, WC2B 6UF, UK.

Background: Local oestrogens, the current treatment for vulvar and vaginal atrophy (VVA), are not suitable for all women. Standard of care (SoC) consists of over-the-counter lubricants and moisturisers. Senshio (ospemifene) provides a treatment option for postmenopausal women who are not candidates for local vaginal oestrogen therapy who would otherwise have an unmet clinical need. Read More

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http://dx.doi.org/10.1007/s40258-020-00589-2DOI Listing

The Inclusion of Comparative Environmental Impact in Health Technology Assessment: Practical Barriers and Unintended Consequences.

Appl Health Econ Health Policy 2020 May 7. Epub 2020 May 7.

College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.

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http://dx.doi.org/10.1007/s40258-020-00578-5DOI Listing

Impact of a Global Pandemic on Health Technology Assessment.

Appl Health Econ Health Policy 2020 Jun;18(3):339-343

Diabetes Trial Unit, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1007/s40258-020-00590-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202921PMC

Economic Theory and Medical Assistance in Dying.

Appl Health Econ Health Policy 2020 May 6. Epub 2020 May 6.

Department of Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1007/s40258-020-00587-4DOI Listing

The Case for a Temporary COVID-19 Income Tax Levy Now, During the Crisis.

Authors:
Jonathan Karnon

Appl Health Econ Health Policy 2020 Jun;18(3):335-337

Flinders Health and Medical Research Institute, Adelaide, Australia.

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http://dx.doi.org/10.1007/s40258-020-00585-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159992PMC

A Systematic Review of the Association Between Hospital Cost/price and the Quality of Care.

Appl Health Econ Health Policy 2020 Apr 15. Epub 2020 Apr 15.

Hamburg Center for Health Economics, University of Hamburg, Hamburg, Germany.

Background: Limited empirical evidence exists regarding the effect of price changes on hospital behavior and, ultimately, the quality of care. Additionally, an overview of the results of prior literature is lacking.

Objective: This study aims to provide a synthesis of existing research concerning the relationship between hospital cost/price and the quality of care. Read More

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http://dx.doi.org/10.1007/s40258-020-00577-6DOI Listing

Health Promoting Schools: An Update.

Appl Health Econ Health Policy 2020 Apr 15. Epub 2020 Apr 15.

Centre for Health Education and Health Promotion, The Chinese University of Hong Kong, 4th Floor, Lek Yuen Health Centre, Shatin, New Territory, Hong Kong.

The concept of a Health Promoting School has been found to be effective to improve health and well-being of students as well as a help with teaching and learning in school. Effective implementation of Health Promoting School is a complex intervention involving multi-factorial and innovative activity in many domains such as curriculum, school environment and community. Many studies evaluating Health Promoting School do not include outcomes reflecting the organisational or structural change as many of those studies are quantitative in nature and the statistical assumptions are not valid reflecting the organisational structure changes. Read More

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http://dx.doi.org/10.1007/s40258-020-00575-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156290PMC

Why Only Test Symptomatic Patients? Consider Random Screening for COVID-19.

Authors:
William V Padula

Appl Health Econ Health Policy 2020 Jun;18(3):333-334

Department of Pharmaceutical and Health Economics, School of Pharmacy, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s40258-020-00579-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138654PMC

COVID-19 Pandemic, a War to be Won: Understanding its Economic Implications for Africa.

Authors:
John E Ataguba

Appl Health Econ Health Policy 2020 06;18(3):325-328

Health Economics Unit, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa.

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http://dx.doi.org/10.1007/s40258-020-00580-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130452PMC

A Simple Decision Analysis of a Mandatory Lockdown Response to the COVID-19 Pandemic.

Authors:
Jonathan Karnon

Appl Health Econ Health Policy 2020 Jun;18(3):329-331

Flinders Health and Medical Research Institute, Adelaide, SA, Australia.

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http://dx.doi.org/10.1007/s40258-020-00581-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130451PMC

Cardiac Resynchronisation Therapy in Patients with Moderate to Severe Heart Failure in Germany: A Cost-Utility Analysis of the Additional Defibrillator.

Appl Health Econ Health Policy 2020 Mar 25. Epub 2020 Mar 25.

Institute of Social Medicine and Epidemiology, University of Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.

Background: Cardiac resynchronisation therapy (CRT) is a well-established form of treatment for patients with heart failure and cardiac dyssynchrony. There are two different types of CRT devices: the biventricular pacemaker (CRT-P) and the biventricular defibrillator (CRT-D). The latter is more complex but also more expensive. Read More

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http://dx.doi.org/10.1007/s40258-020-00571-yDOI Listing

Effects of Monetary Incentives in Physician Groups: A Systematic Review of Reviews.

Appl Health Econ Health Policy 2020 Mar 23. Epub 2020 Mar 23.

Master Program Medical Process Management, Universitätsklinikum Erlangen, Erlangen, Germany.

Background: Reimbursement systems that contribute to the cooperation and integration of providers have become increasingly important within the healthcare sector. Reimbursement systems not only serve as payment mechanisms but also provide control and incentive functions. Thus, the design of reimbursement systems is extremely important. Read More

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http://dx.doi.org/10.1007/s40258-020-00572-xDOI Listing

Comment on: "A Multinational European Study of Patient Preferences for Novel Diagnostics to Manage Antimicrobial Resistance".

Authors:
J P Hays

Appl Health Econ Health Policy 2020 Jun;18(3):457-458

Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre (Erasmus MC), Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40258-020-00574-9DOI Listing

Authors' Reply to Hays: "A Multinational European Study of Patient Preferences for Novel Diagnostics to Manage Antimicrobial Resistance".

Appl Health Econ Health Policy 2020 Jun;18(3):459-460

Science Policy Research Unit, University of Sussex Business School, Jubilee Building, Falmer, Brighton, UK.

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http://dx.doi.org/10.1007/s40258-020-00573-wDOI Listing

Performance-Based Financing, Basic Packages of Health Services and User-Fee Exemption Mechanisms: An Analysis of Health-Financing Policy Integration in Three Fragile and Conflict-Affected Settings.

Appl Health Econ Health Policy 2020 Mar 20. Epub 2020 Mar 20.

ReBUILD and Institute for Global Health and Development, Queen Margaret University, Edinburgh, UK.

Background: As performance-based financing (PBF) is increasingly implemented across sub-Saharan Africa, some authors have suggested that it could be a 'stepping stone' for health-system strengthening and broad health-financing reforms. However, so far, few studies have looked at whether and how PBF is aligned to and integrated with national health-financing strategies, particularly in fragile and conflict-affected settings.

Objective: This study attempts to address the existing research gap by exploring the role of PBF with reference to: (1) user fees/exemption policies and (2) basic packages of health services and benefit packages in the Central African Republic, Democratic Republic of Congo and Nigeria. Read More

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http://dx.doi.org/10.1007/s40258-020-00567-8DOI Listing

Economics of Mental Health: Providing a Platform for Efficient Mental Health Policy.

Appl Health Econ Health Policy 2020 04;18(2):143-145

Centre for Health Economics Research and Evaluation and the Centre for Improving Palliative, Aged and Chronic Care Through Clinical Research and Translation, University of Technology Sydney, Ultimo, Australia.

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http://dx.doi.org/10.1007/s40258-020-00569-6DOI Listing

Estimating the Unit Costs of Healthcare Service Delivery in India: Addressing Information Gaps for Price Setting and Health Technology Assessment.

Appl Health Econ Health Policy 2020 Mar 14. Epub 2020 Mar 14.

Department of Community Medicine and School of Public Health, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Background: India's flagship National Health insurance programme (AB-PMJAY) requires accurate cost information for evidence-based decision-making, strategic purchasing of health services and setting reimbursement rates. To address the challenge of limited health service cost data, this study used econometric methods to identify determinants of cost and estimate unit costs for each Indian state.

Methods: Using data from 81 facilities in six states, models were developed for inpatient and outpatient services at primary and secondary level public health facilities. Read More

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http://dx.doi.org/10.1007/s40258-020-00566-9DOI Listing

Cost-Effectiveness of Subsequent Whole-Brain Radiotherapy or Hippocampal-Avoidant Whole-Brain Radiotherapy Versus Stereotactic Radiosurgery or Surgery Alone for Treatment of Melanoma Brain Metastases.

Appl Health Econ Health Policy 2020 Mar 11. Epub 2020 Mar 11.

Health Economics, National Drug and Alcohol Research Centre, University of New South Wales, 22-32 King street, Sydney, NSW, 2031, Australia.

Background: A randomized phase III trial comparing whole-brain radiotherapy (WBRT) to observation following definitive local treatment of intracranial melanoma metastases with neurosurgery and/or stereotactic surgery (SRS) is underway.

Objective: We sought to assess the pre-trial cost-effectiveness of WBRT, hippocampal-avoidant WBRT (HA-WBRT), and observation (SRS or surgery alone) for this population to guide trial data collection efforts and reduce decision uncertainty.  METHODS: A time-dependent Markov model followed patients treated with neurosurgery or SRS who received subsequent WBRT, HA-WBRT or observation over a 5-year time horizon. Read More

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http://dx.doi.org/10.1007/s40258-020-00560-1DOI Listing

Cost-Effectiveness Analysis of Supervised Exercise Training in Men with Prostate Cancer Previously Treated with Radiation Therapy and Androgen-Deprivation Therapy.

Appl Health Econ Health Policy 2020 Feb 28. Epub 2020 Feb 28.

Centre for Applied Health Economics, Griffith University, Nathan, QLD, Australia.

Background: Exercise for prostate cancer (PCa) survivors has been shown to be effective in addressing metabolic function and associated co-morbidities, as well as sarcopenia and significant functional impairment resulting from long-term androgen deprivation. Evidence on the cost-effectiveness of exercise interventions for PCa, however, is lacking, thus the aim of this study was to determine the cost-effectiveness of a supervised exercise intervention for long-term PCa survivors who previously received radiation therapy and androgen-deprivation therapy.

Methods: Cost-effectiveness analysis from an Australian healthcare-payer perspective was conducted using patient-level data from a multicentre randomised controlled trial (RCT) of supervised exercise training (resistance and aerobic) compared to receiving printed exercise material and a recommendation to exercise in long-term PCa survivors (> 5 years post-diagnosis). Read More

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http://dx.doi.org/10.1007/s40258-020-00564-xDOI Listing
February 2020

The Potential Benefits of Deferred Payment for a Hypothetical Gene Therapy for Congestive Heart Failure: A Cost-Consequence Analysis.

Appl Health Econ Health Policy 2020 Feb 24. Epub 2020 Feb 24.

RAND Corporation, 1776 Main Street, Santa Monica, CA, 90401, USA.

Background: The emergence of potentially curative pharmacologic treatments that deliver long-term clinical benefits with a limited number of doses may create short-term budget challenges for payers as their unit price can be high.

Objective: This paper tests the clinical and financial properties of a deferred payment model (DPM) in hypothetical therapy for congestive heart failure (CHF) from the perspective of payers, manufacturers, and patients.

Methods: We present an empirical analysis of longitudinal data for cardiovascular admissions and mortality using a Markov transition model for patient progression under different payment scenarios. Read More

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http://dx.doi.org/10.1007/s40258-020-00563-yDOI Listing
February 2020

Cost-Utility of Internet-Based Cognitive Behavioral Therapy in Unipolar Depression: A Markov Model Simulation.

Appl Health Econ Health Policy 2020 Feb 15. Epub 2020 Feb 15.

Hamburg Center for Health Economics (HCHE), Universität Hamburg, Esplanade 36, 20354, Hamburg, Germany.

Background And Objective: Unipolar depression is the most common form of depression and demand for treatment, such as psychotherapy, is high. However, waiting times for psychotherapy often considerably exceed their recommended maximum. As a potentially less costly alternative treatment, internet-based cognitive behavior therapy (ICBT) might help reduce waiting times. Read More

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http://dx.doi.org/10.1007/s40258-019-00551-xDOI Listing
February 2020

Economic Evaluations of Anticancer Drugs Based on Medico-Administrative Databases: A Systematic Literature Review.

Appl Health Econ Health Policy 2020 Feb 14. Epub 2020 Feb 14.

Department of Economic and Public Health Evaluation, French National Authority for Health (Haute Autorité de Santé, HAS), 5 Avenue du Stade de France, 93218, Saint-Denis La Plaine CEDEX, France.

Background: Oncology is among the most active therapeutic fields in terms of new drug development projects, with increasingly expensive drugs. The expected clinical benefit and cost effectiveness of these treatments in clinical practice have yet to be fully confirmed. Health medico-administrative databases may be useful for assessing the value of anticancer drugs with real-world data. Read More

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http://dx.doi.org/10.1007/s40258-020-00562-zDOI Listing
February 2020

The Potential Role of Constrained Optimization Methods in Healthcare Decision Making.

Authors:
William H Crown

Appl Health Econ Health Policy 2020 Feb 7. Epub 2020 Feb 7.

OptumLabs, Cambridge, MA, 02494, USA.

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http://dx.doi.org/10.1007/s40258-020-00559-8DOI Listing
February 2020

What Matters to Potential Patients in Chemotherapy Service Delivery? A Discrete Choice Experiment.

Appl Health Econ Health Policy 2020 Feb 6. Epub 2020 Feb 6.

School of Public Health, Curtin University, Perth, WA, 6845, USA.

Introduction: Designing and funding chemotherapy care to meet patient expectations is challenging. Issues including convenience, outcomes, cost, and continuity of care are all potentially important and the appropriate trade-off between them is not clear. Regions with significant geographic spread and concentration of care in metropolitan areas pose a particular problem as ensuring low-cost convenient care is potentially difficult. Read More

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http://dx.doi.org/10.1007/s40258-020-00555-yDOI Listing
February 2020

Should Health Economic Evaluations Undertaken from a Societal Perspective Include Net Government Spending Multiplier Effects?

Appl Health Econ Health Policy 2020 Feb 4. Epub 2020 Feb 4.

South Australian Ambulance Service, Adelaide, SA, Australia.

The fiscal multiplier represents the ratio of the change in national income to an associated increase in government spending. Fiscal multiplier effects are commonly estimated to justify options for government spending. Multiplier effects are not considered in economic evaluations of healthcare, but alternate forms of healthcare spending are expected to have varying multiplier effects. Read More

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http://dx.doi.org/10.1007/s40258-020-00556-xDOI Listing
February 2020

Authors' Reply to Garattini and Freemantle: "Value-Based Pricing Alternatives for Personalised Drugs: Implications of Asymmetric Information and Competition".

Appl Health Econ Health Policy 2020 Jun;18(3):455-456

Department of Economics, University of Verona, Via Cantarane, 24, 37129, Verona, Italy.

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http://dx.doi.org/10.1007/s40258-020-00557-wDOI Listing

Comment on: 'Value-Based Pricing Alternatives for Personalised Drugs: Implications of Asymmetric Information and Competition'.

Appl Health Econ Health Policy 2020 Jun;18(3):453-454

Institute of Clinical Trials and Methodology, University College London, London, UK.

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http://dx.doi.org/10.1007/s40258-020-00552-1DOI Listing

Estimating the Productivity Burden of Pediatric Pneumococcal Disease in Thailand.

Appl Health Econ Health Policy 2020 Feb 3. Epub 2020 Feb 3.

Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA.

Background: Pneumococcal diseases were estimated to cause 1.6 million deaths annually worldwide in 2008, with approximately half of these occurring in children aged under 5 years. The consequences and deaths adversely impact individuals' and caregivers' work productivity. Read More

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http://dx.doi.org/10.1007/s40258-020-00553-0DOI Listing
February 2020

Promoting HIV Testing by Men: A Discrete Choice Experiment to Elicit Preferences and Predict Uptake of Community-based Testing in Uganda.

Appl Health Econ Health Policy 2020 Jun;18(3):413-432

Department of Medical Ethics & Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Background And Objectives: HIV testing is essential to access HIV treatment and care and plays a critical role in preventing transmission. Despite this, testing coverage is low among men in sub-Saharan Africa. Community-based testing has demonstrated potential to expand male testing coverage, yet scant evidence reveals how community-based services can be designed to optimize testing uptake. Read More

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http://dx.doi.org/10.1007/s40258-019-00549-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255957PMC

Preferences for Weight Loss Treatment Amongst Treatment-Seeking Patients with Severe Obesity: A Discrete Choice Experiment.

Appl Health Econ Health Policy 2020 Jan 23. Epub 2020 Jan 23.

Centre for Public Health, Queens University Belfast, Belfast, UK.

Background: Treatment options for weight loss vary considerably with regard to risks and benefits, but the relative importance of treatment characteristics in patient decision-making is largely unknown, particularly amongst patients with severe obesity. Developing such services requires insight into the preferences of recipients for service attributes.

Objective: The objective of this study was to quantify, using a discrete choice experiment, the preferences of treatment-seeking patients with severe obesity within the Irish population regarding different attributes of various obesity treatments. Read More

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http://dx.doi.org/10.1007/s40258-020-00554-zDOI Listing
January 2020

Payment Arrangements for Private Healthcare Purchasing Under Publicly Funded Systems in Low- and Middle-Income Countries: Issues and Implications.

Appl Health Econ Health Policy 2020 Jan 22. Epub 2020 Jan 22.

Health Economics Unit, University of Cape Town, Cape Town, South Africa.

This paper examines private healthcare purchasing under publicly financed health systems in low- and middle-income countries (LMICs) to argue that the payment methods and rates applied to private and public health providers need careful attention to ensure equity, efficiency and quality in healthcare service provision. Specifically, public purchasers should develop a clear mechanism to establish justifiable payment rates for the purchase of private health services under publicly funded systems, using cost information and appropriate engagement with private health providers. In order to determine the validity of payment arrangements with private providers, clarification of the shared roles and responsibilities of public and private healthcare providers is required, including specification of types of services to be delivered by public and private providers, and the services for which public providers receive government budget and salaries above payments for other publicly funded services. Read More

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http://dx.doi.org/10.1007/s40258-019-00550-yDOI Listing
January 2020

Health State Values of Deaf British Sign Language (BSL) Users in the UK: An Application of the BSL Version of the EQ-5D-5L.

Appl Health Econ Health Policy 2020 Jan 16. Epub 2020 Jan 16.

Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Centre for Health Economics, Oxford Road, Manchester, M13 9PL, UK.

Background: Deaf people experience health inequalities compared to hearing populations. The EQ-5D, a widely used, standardised, generic measure of health status, which is available in over 100 languages, was recently translated into British Sign Language (BSL) and initial validation conducted. Using data from this previous study of the EQ-5D-5L BSL we aimed to assess (1) whether responses to the EQ-5D differed between a sample of Deaf BSL users and the general population (2) whether socio-demographic characteristics and clinical measures were associated with EQ-5D index scores in Deaf BSL users and (3) the impact of psychological distress and depression on health status in Deaf BSL users. Read More

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http://dx.doi.org/10.1007/s40258-019-00546-8DOI Listing
January 2020

Correction to: Cost Effectiveness of Cladribine Tablets for the Treatment of Relapsing-Remitting Multiple Sclerosis in The Netherlands.

Appl Health Econ Health Policy 2020 Feb;18(1):141

IQVIA, Real World Evidence Solutions, Herikerbergweg 314, 1101 CT, Amsterdam, The Netherlands.

The second author's name should be "Maria De Francesco" rather than "Maria de Fransesco". Read More

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http://dx.doi.org/10.1007/s40258-019-00548-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978442PMC
February 2020

Comparison of Utilization Trends between Biosimilars and Generics: Lessons from the Nationwide Claims Data in South Korea.

Appl Health Econ Health Policy 2020 Jan 13. Epub 2020 Jan 13.

College of Pharmacy, Yonsei Institute for Pharmaceutical Research, Yonsei University, 162-1 Songdo-Dong, Yeonsu-Gu, Incheon, South Korea.

Background: South Korea is unique in that it leads global markets in R&D as well as production of biosimilar products and was the first market into which some biosimilar products were introduced. We analyzed the time trend of market penetration and simulated saved spending by biosimilars in South Korea.

Methods: We pulled Korean National Health Insurance claims data from January 2012-December 2018 for second-generation biologics, including infliximab, rituximab, and trastuzumab, and examined the time trends of expenditure, utilization in defined daily dose, and price. Read More

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http://dx.doi.org/10.1007/s40258-019-00547-7DOI Listing
January 2020

Do Research Groups Align on an Intervention's Value? Concordance of Cost-Effectiveness Findings Between the Institute for Clinical and Economic Review and Other Health System Stakeholders.

Appl Health Econ Health Policy 2020 Jan 10. Epub 2020 Jan 10.

Boston Health Economics, LLC, 265 Franklin Street, Suite 1101, Boston, MA, 02110, USA.

The Institute for Clinical and Economic Review (ICER) employs fixed cost-effectiveness (CE) thresholds that guide their appraisal of an intervention's long-term economic value. Given ICER's rising influence in the healthcare field, we undertook an assessment of the concordance of ICER's CE findings to the published CE findings from other research groups (i.e. Read More

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http://dx.doi.org/10.1007/s40258-019-00545-9DOI Listing
January 2020

The Impact of Physicians' Working Hours on Inappropriate Use of Outpatient Medicine in a Tertiary Hospital in China.

Appl Health Econ Health Policy 2020 Jun;18(3):443-451

Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, 02215, USA.

Background: Inappropriate prescribing is an important health system problem in China. Several studies have identified critical factors influencing prescription quality, but the impact of physicians' working hours remains unknown. In China, tertiary hospitals face ever-increasing outpatient volumes. Read More

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http://dx.doi.org/10.1007/s40258-019-00544-wDOI Listing

iFuse Implant System for Treating Chronic Sacroiliac Joint Pain: A NICE Medical Technology Guidance.

Appl Health Econ Health Policy 2020 Jun;18(3):363-373

Cedar, Cardiff & Vale University Health Board, Cardiff, UK.

Treatment and management of sacroiliac joint pain is often non-surgical, involving packages of care that can include analgesics, physiotherapy, corticosteroid injections and radiofrequency ablation. Surgical intervention is considered when patients no longer respond to conservative management. The iFuse Implant System is placed across the sacroiliac joint using minimally invasive surgery, stabilising the joint and correcting any misalignment or weakness that can cause chronic pain. Read More

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http://dx.doi.org/10.1007/s40258-019-00539-7DOI Listing

Comment on: "Projections of the Healthcare Costs and Disease Burden due to Hepatitis C Infection Under Different Treatment Policies in Malaysia, 2018-2040".

Appl Health Econ Health Policy 2020 02;18(1):139-140

Clinical Research Center, Sultanah Bahiyah Hospital, Ministry of Health, Alor Setar, Kedah, Malaysia.

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http://dx.doi.org/10.1007/s40258-019-00543-xDOI Listing
February 2020

Cost-Effectiveness of Extended and One-Time Screening Versus No Screening for Non-Valvular Atrial Fibrillation in the USA.

Appl Health Econ Health Policy 2019 Dec 17. Epub 2019 Dec 17.

University of Southern California, Los Angeles, CA, USA.

Background: There is limited evidence on the clinical and cost benefits of screening for atrial fibrillation (AF) with electrocardiogram (ECG) in asymptomatic adults.

Methods: We adapted a previously published Markov model to evaluate the clinical and economic impact of one-time screening for non-valvular AF (NVAF) with a single 12-lead ECG and a 14-day extended screening with a hand-held ECG device (Zenicor single-lead ECG, Z14) compared with no screening. Clinical events considered included ischemic stroke, systemic embolism, major bleeds, myocardial infarction, and death. Read More

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http://dx.doi.org/10.1007/s40258-019-00542-yDOI Listing
December 2019

Incorporating the Environmental Impact into a Budget Impact Analysis: The Example of Adopting RESPIMAT Re-usable Inhaler.

Appl Health Econ Health Policy 2020 Jun;18(3):433-442

Miltenburger Consulting, Berlin, Germany.

Background: RESPIMAT re-usable enables patients to re-use the inhaler and its availability therefore reduces the number of inhalers and associated wastage.

Objective: The objective of this study was to perform an economic evaluation that incorporates the ecological impact of adopting RESPIMAT re-usable into the healthcare system in Germany.

Methods: Inhaler costs and environmental impact over 5 years in Germany in a scenario with RESPIMAT re-usable compared to a scenario without RESPIMAT re-usable were estimated using a budget impact model. Read More

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http://dx.doi.org/10.1007/s40258-019-00540-0DOI Listing

The Relevant Perspective of Economic Evaluations Informing Local Decision Makers: An Exploration in Weight Loss Services.

Appl Health Econ Health Policy 2020 Jun;18(3):351-356

Centre for Health Economics, Alcuin 'A' Block, University of York, Heslington, North Yorkshire, YO10 5DD, UK.

Since 2013, obesity services in the UK National Health Service (NHS) have focused on a tiered structure, with tiers 3 (specialist weight management services) and 4 (primarily bariatric surgery) commissioned by Clinical Commissioning Groups (CCGs) and widely reported as cost effective and recommended by national guidelines. However, CCGs have been reluctant to fully conform to the guidance. We explore how the different evaluative perspective of those generating evidence from local decision makers has contributed to this failure of the CCGs to provide services considered cost effective. Read More

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http://dx.doi.org/10.1007/s40258-019-00538-8DOI Listing

Value-Based Pricing Alternatives for Personalised Drugs: Implications of Asymmetric Information and Competition.

Appl Health Econ Health Policy 2020 Jun;18(3):357-362

Department of Economics, University of Verona, Verona, Italy.

The market for new drugs is changing: personalised drugs will increase the heterogeneity in patients' responses and, possibly, costs. In this context, price regulation will play an increasingly important role. In this article, we argue that personalised medicine opens new scenarios in the relationship between value-based prices, regulation and industry listing strategies. Read More

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http://dx.doi.org/10.1007/s40258-019-00541-zDOI Listing