8,404 results match your criteria Applied Radiation And Isotopes[Journal]


Imaging and biodistribution of radiolabeled SP90 peptide in BT-483 tumor bearing mice.

Appl Radiat Isot 2020 Jul 2;161:109162. Epub 2020 Apr 2.

Isotope Application Division, Institute of Nuclear Energy Research, Taoyuan, Taiwan. Electronic address:

The objective of this study was to evaluate radiolabeled DOTA-SP90 as a radiotracer for breast cancer. The in vitro competition assay showed that radiolabeled DOTA-SP90 had significant binding affinity to BT-483 cancer cells. Biodistribution, nanoSPECT/CT and nanoPET/CT imaging results indicated that radiolabeled DOTA-SP90 can accumulate in tumors. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109162DOI Listing

Efficiency of a cubic NaI(Tl) detector with rectangular cavity using standard radioactive point sources placed at non-axial position.

Appl Radiat Isot 2020 Sep 24;163:109139. Epub 2020 Mar 24.

Physics Department, Faculty of Science, Alexandria University, 21511, Alexandria, Egypt. Electronic address:

Low cost scintillation detectors as compared with HPGe detectors are considered to be one of most important radiation detection tools. Therefore, these detectors can be manufactured in different shapes and work at room temperature without any cooling systems, which added an extra advantage to it. This work presents a study of a cubic detector with a rectangular cavity in different experimental setup geometries, using standard point-like gamma-ray sources, where the efficiency of the detector in these geometries was the target to be studied. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109139DOI Listing
September 2020

The empirical cross section behavior of (d, 3n) reaction for 20±1.5 MeV energy.

Authors:
Y Kavun

Appl Radiat Isot 2020 Sep 29;163:109241. Epub 2020 May 29.

Vocational School of Health Services, Dept. of Medical Imaging Techniques, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey. Electronic address:

Many nuclear reaction cross-section formalism has been developed for particle induced reaction up to date. In this study, a new empirical (d, 3n) cross section formulae systematic have been developed at 45≤A≤112 mass range for 20 ± 1.5 MeV incident deuterium energy. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109241DOI Listing
September 2020

Analysis of 7-years Radon time series at Campi Flegrei area (Naples, Italy) using artificial neural network method.

Appl Radiat Isot 2020 Sep 24;163:109239. Epub 2020 May 24.

National Institute of Geophysics and Volcanology (INGV), Bologna Branch, Via D. Creti 12, 40124, Bologna, Italy.

This paper reports the analysis of soil Rn data recorded over 7-years in the volcanic caldera of Campi Flegrei (Naples-Italy). The relationship between Radon activity concentration and several geophysical, geochemical and meteorological parameters, influencing the gas emissions, is estimated by the Artificial Neural Network (ANN) method. The analysis goals are: the estimation (replication) of the Radon time series from influencing parameters, the forecasting of an unknown part of it, and the search for anomalies. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109239DOI Listing
September 2020

Phantom dosimetry and cancer risks estimation undergoing 6 MV photon beam by an Elekta SL-25 linac.

Authors:
Rahim Khabaz

Appl Radiat Isot 2020 Sep 23;163:109232. Epub 2020 May 23.

Department of Physics, Faculty of Sciences, Golestan University, Gorgan, 49138-15739, Iran. Electronic address:

The High-energy linear accelerator (linac) is a valuable tool and the most commonly used devices for external beam radiation treatments in subjects suffer from cancer. To estimate the dose deposited in several organs of a female patient due to pelvic irradiation by an Elekta SL-25 linac in 6 MV photon beam mode, the MCNPX code is used considering the most details of linac. The equivalent dose in different organs is computed according to the face down position (prone) of MIRD and UFRO phantoms. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109232DOI Listing
September 2020

A NaI(Tl)-based radioactive noble-gas monitoring system used for radiation monitoring.

Appl Radiat Isot 2020 Sep 20;163:109230. Epub 2020 May 20.

Northwest Institute for Nuclear Technology, P.O. Box 69-27, Xi'an, 710024, Shanxi, China.

Radioactive noble-gas monitoring is necessary in nuclear facilities. A NaI(Tl)-based radioactive noble-gas monitoring system was developed. In order to increase the amount of air to be measured, the sample vessel of this system was larger than that of other systems, and was pressurized to about 5 × 10 Pa. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109230DOI Listing
September 2020

Verification of physical parameters of insity p-type HPGe detector by scan method using collimated low energy photon beam and MNCP simulation.

Appl Radiat Isot 2020 Sep 22;163:109229. Epub 2020 May 22.

Radiation Protection and Environment Monitoring, Center for Nuclear Techniques, Ho Chi Minh City, Viet Nam.

In this work, the physical dimensions and the actual position of germanium crystal within a detector housing, the homogeneity of the crystal surface and outer dead layer thickness for a p-type HPGe detector were confirmed by the scan method using the collimated low energy photon beams combined with Monte Carlo simulation. The length and the diameter of the crystal were found to match with the values supplied by the manufacturer in discrepancy of about 3%. Only one mounting strap (Typical) for holding the crystal inside the mounting cup instead of two which is indicated in the detector drawing supplied by manufacturer was revealed by scanning along the lateral face of detector. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109229DOI Listing
September 2020

Characterization of Cm neutron sources.

Appl Radiat Isot 2020 Sep 20;163:109225. Epub 2020 May 20.

Los Alamos National Laboratory, PO Box 1663, MS J-573, Los Alamos, NM, 87545, USA. Electronic address:

There is a need to find a replacement for the Cf sources currently used in Standards-based performance testing of neutron instrumentation. This is a result of its relatively short half-life, concerns about future availability and recent increases in cost. A potential replacement source, Cm is evaluated in this study where two commercially available sources have been acquired and their neutron emission spectra measured using a pair of spectrometers. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109225DOI Listing
September 2020

Influence of γ-irradiation and oxygen conditions on the diffusion of I-125 in crushed Beishan granite.

Appl Radiat Isot 2020 Sep 21;163:109224. Epub 2020 May 21.

Radiochemistry Lab, School of Nuclear Science and Technology, Lanzhou University, 730000, Lanzhou, PR China; Key Laboratory of Special Function Materials and Structure Design, Ministry of Education, Lanzhou University, 730000, Lanzhou, PR China. Electronic address:

The diffusion of iodine (labeled with I) in compacted Beishan granite (BsG) was investigated using the in-diffusion capillary method at pH ~2.0 to ~11.0 under oxygen and irradiation conditions. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109224DOI Listing
September 2020
1.056 Impact Factor

On the photomultiplier-tube asymmetry in TDCR systems.

Appl Radiat Isot 2020 Sep 15;163:109223. Epub 2020 May 15.

National Institute of Metrology (NIM), 100029, Beijing, China.

The responses of the three photomultiplier tubes (PMTs) in a triple-to-double coincidence ratio (TDCR) liquid scintillation (LS) system are often not identical. Such asymmetries can have a significant influence on activity determinations. The problem is often solved by means of a minimization algorithm which can easily be applied when analytical methods are used for the efficiency calculation, as is usually done for pure beta emitters. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109223DOI Listing
September 2020

The importance of optimal ROIs delineation for FBPA-PET before BNCT.

Appl Radiat Isot 2020 Sep 13;163:109219. Epub 2020 May 13.

Division of Radiotherapy, Department of Oncology Medicine, Taipei Veterans General Hospital, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

One of the eligible criteria for patients to receive boron neutron capture therapy (BNCT) is based on the tumour-to-normal ratio (T/N) measured by FBPA-PET. However, there is no standard protocol for normal region-of-interested delineation. With comparison of contralateral cerebrum, our study revealed the consistency (p < 0. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109219DOI Listing
September 2020

Exploring neutron capture therapy with S and B.

Appl Radiat Isot 2020 Sep 16;163:109220. Epub 2020 May 16.

Universidad de Granada, Granada, Spain.

The S(n,α)Si reaction was proposed as cooperative neutron capturer to B(n,α)Li in Neutron Capture Therapy (NCT). At that moment, the available S(n,α)Si cross-section data were scarce and discrepant in key energy ranges for its use in NCT. Since then, three experiments have been carried out at n_TOF facility at CERN and at Institut Laue-Langevin. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109220DOI Listing
September 2020

A new formulae study for the (n,2p) reaction cross-section systematics at 14-15 MeV.

Appl Radiat Isot 2020 Sep 13;163:109218. Epub 2020 May 13.

Osmaniye Korkut Ata University, Faculty of Arts and Sciences, Dept. of Physics, Osmaniye, Turkey. Electronic address:

The cross-section calculation systematics for nuclear reactions have great importance in describing the particle-induced excitation of nuclei. In this study, for 14-15 MeV of incident neutron energy, it has been suggested new empirical formulae to describe the (n, 2p) reactions cross sections. The new empirical formulae have been obtained for 29≤A≤159, 29≤A≤103 and 133≤A≤159 mass ranges which are dependent on s=(N-Z)/A asymmetry parameter. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109218DOI Listing
September 2020

Image reconstruction using multi-energy system matrices with a scintillator-based gamma camera for nuclear security applications.

Appl Radiat Isot 2020 Sep 11;163:109217. Epub 2020 May 11.

College of Nuclear Technology and Automation Engineering, Chengdu University of Technology, Chengdu, 610059, PR China.

The system response of a gamma camera is dependent on the photon energy, thus the energy-dependent response function needs to be considered to improve the quality and fidelity of reconstructed images for identifying radionuclides in security applications. In this study, two reconstruction strategies using the maximum-likelihood expectation maximization (MLEM) algorithm with the multi-energy system matrices calculated by Monte Carlo simulations are proposed. The difference between the two is in data acquisition; one uses the sum of all events into a single projection image while the other sorts them into separate energy windows. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109217DOI Listing
September 2020

The next generation of current measurement for ionization chambers.

Appl Radiat Isot 2020 Sep 13;163:109216. Epub 2020 May 13.

NIST, USA.

Re-entrant ionization chambers (ICs) are essential to radionuclide metrology and nuclear medicine for maintaining standards and measuring half-lives. The requirements of top-level metrology demand that systems must be precise and stable to 0.1 % over many years, and linear from 10 A to 10 A. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109216DOI Listing
September 2020

Biodistribution studies of boronophenylalanine in different types of skin melanoma.

Appl Radiat Isot 2020 Sep 11;163:109215. Epub 2020 May 11.

China Zhongyuan Engineering Corporation(CZEC), China.

A study of the B-enriched Boronophenylalanine-fructose complex(BPA-F) infusion procedure in potential BNCT patients, including three skin melanomas of extremities, was performed. B concentration in tumor(T), blood(B), skin(S) were measured to determine tumor/blood(T/B) and skin/blood(S/B) ratios. T/B ratio for three melanoma patients was in the range 1. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109215DOI Listing
September 2020
1.056 Impact Factor

Evaluation of the energy resolution of a prompt gamma-ray imaging detector using LaBr(Ce) scintillator and 8 × 8 array MPPC for an animal study of BNCT.

Appl Radiat Isot 2020 Sep 19;163:109214. Epub 2020 May 19.

Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.

To develop boron neutron capture therapy (BNCT), it is desired to measure B concentration and obtain a two-dimensional B distribution in animal studies. In this research, we develop a prompt gamma-ray imaging detector to measure B distribution using a 50 mm × 50 mm x 10 mm LaBr(Ce) scintillator and a multi-pixel photon counter (MPPC). To measure a two-dimensional B distribution, the 478 keV gamma-ray emitted from B(n,α)Li reaction should be measured with the discrimination from 511 keV background gamma rays in each MPPC. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109214DOI Listing
September 2020

A study on remotely-changeable moderators in Bonner sphere spectrometer for irradiation-field characterization in boron neutron capture therapy.

Appl Radiat Isot 2020 Sep 11;163:109213. Epub 2020 May 11.

Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan. Electronic address:

As part of the advancements in the characterization of the irradiation field for boron neutron capture therapy, we are developing a Bonner-sphere neutron energy spectrometer for which the liquid moderator is changed remotely. Simulations were performed to find the best combination of liquid moderators and composition of the Bonner spheres. The combination finally adopted was five-layered concentric acrylic spheres with two different liquid moderators and six optimal patterns for moderator injection. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109213DOI Listing
September 2020

Preparation and characterization of poly nano-cerium chloride for Mo production based on neutron activation reactions.

Appl Radiat Isot 2020 Sep 23;163:109211. Epub 2020 May 23.

Faculty of Science, Benha University, P.O. Box 13518, Benha, Egypt.

Different molar ratios of the cerium trichloride heptahydrate to isopropyl alcohol (1:2, 1:3 and 1:5) were studied to choose the optimum ratio, and studied the reaction temperature effect (80, 90 and 100 °C) to determine the optimum temperature for the preparation of poly nano cerium chloride (PNCC). The PNCC-1 was selected among the prepared PNCC batches based on the Mo sorption properties that confirms the feasibility of using it as a novel effective sorbent material. The structural properties and chemical composition were studied using different techniques and devices such as EDX, XRD, FESEM, FTIR, TGA, and DTA. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109211DOI Listing
September 2020

Review of recent radon research in Ireland, OPTI-SDS project and its impact on the National Radon Control Strategy.

Appl Radiat Isot 2020 Sep 11;163:109210. Epub 2020 May 11.

School of Physics, National University of Ireland Galway, Ireland. Electronic address:

Radon is a radioactive gas originating from uranium, present in all rocks and soils in the Earth's Crust; emanating from the ground, radon can be released into the atmosphere. It is the greatest source of natural radioactivity exposure for the population and, as declared by the World Health Organization (WHO), the leading cause of lung cancer only after smoking. Although radon is a natural gas, its accumulation provoking elevated indoor radon levels is a result from building practices and thus, not natural. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109210DOI Listing
September 2020

Boron neutron capture therapy for head and neck cancer: Relevance of nuclear-cytoplasmic volume ratio and anti-tumor effect. -A preliminary report.

Appl Radiat Isot 2020 Sep 20;163:109212. Epub 2020 May 20.

Kansai BNCT Medical Center and Department of Otolaryngology Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan.

BNCT is a type of particle beam radiation therapy that utilizes an α particle and 7Li nucleus generated when a thermal neutron is captured by a 10B nucleus involved in the boron compound that has been taken up into tumor tissue selectively. In this report, the relevance of N/C ratio of tumor cell and anti-tumor effect for BNCT clinical cases of head and neck cancer were verified. Examination of pre-irradiated tumor histopathological specimens of 9 BNCT treated head and neck cancer patients (4 CR patients, 5 non-CR patients) was performed. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109212DOI Listing
September 2020

Monte Carlo characterization of the cosmic ray muon flux in shallow subsurface geological repositories intended for disposal of radioactive materials.

Appl Radiat Isot 2020 Sep 11;163:109209. Epub 2020 May 11.

School of Nuclear Science and Engineering, Oregon State University, Corvallis, OR, 97331, USA.

Recent challenges in monitoring subsurface geological repositories intended for disposal of radioactive materials such as spent nuclear fuel call for new, innovative concepts that are facility independent, cost-effective, passive, and reliable. Once nuclear material is in place at these facilities, reverifying the inventory may no longer be feasible if continuity of knowledge is lost or unavailable to the inspectors. Using cosmic ray muons may present several potential advantages over conventional photon/neutron signatures, and their use in safeguards applications have only received attention in the past decade. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109209DOI Listing
September 2020

Monitoring patient movement with boron neutron capture therapy and motion capture technology.

Appl Radiat Isot 2020 Sep 4;163:109208. Epub 2020 May 4.

Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

In boron neutron capture therapy (BNCT), a patient must remain in a fixed position during the irradiation process. In this study, a system was devised that can guide a patient to the correct position and the patient can be monitored during the irradiation process. This is achieved by using motion capture technology that consists of many cameras. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109208DOI Listing
September 2020

Radioactivity induced in new-generation cardiac implantable electronic devices during high-energy X-ray irradiation.

Appl Radiat Isot 2020 Sep 1;163:109206. Epub 2020 May 1.

3rd Chair and Department of Cardiology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.

This study provides the first insight into the problem of the induced radioactivity of the construction materials of the new-generation cardiac implantable electronic devices (CIEDs). Its aim was to identify nuclear reactions and the resulting radioisotopes induced in the CIEDs by high-energy X-ray therapeutic beams generated by medical linear accelerators. The presented results allow to verify the rightness of choice of materials for investigated CIEDs. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109206DOI Listing
September 2020

The combined effect of neutron irradiation and temozolomide on glioblastoma cell lines with different MGMT and P53 status.

Appl Radiat Isot 2020 Sep 25;163:109204. Epub 2020 Apr 25.

Institute for Integrated Radiation and Nuclear Science Kyoto University, Kumatori-cho, Sennan-gun, Osaka, 590-0494, Japan.

Temozolomide (TMZ) is a DNA-alkylating agent used for chemo-radiotherapy of glioblastoma, which is also a target cancer for boron neutron capture therapy (BNCT). Although the DNA-repair enzyme O-methylguanine DNA methyltransferase (MGMT) and the tumor suppressor p53 are mutated in some glioblastoma cells, it remains unknown whether these mutations affect sensitivity to neutron irradiation. We examined sensitivity to neutron irradiation and TMZ in two glioblastoma cell lines: T98G, which is p53-mutant with high levels of MGMT activity; and A172, which is p53-wild-type and has low MGMT activity. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109204DOI Listing
September 2020

Single-dose toxicity study by intra-arterial injection of BSH entrapped water-in-oil-in-water emulsion for boron neutron capture therapy to hepatocellular carcinoma.

Appl Radiat Isot 2020 Sep 13;163:109202. Epub 2020 May 13.

Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan; Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan.

We developed a mixing medical device by attaching Shirasu porous glass Millipore membrane to prepare water-in-oil-in-water (WOW) emulsion in a shorter time to be applied as B-entrapped WOW emulsion for hepatocellular carcinoma (HCC) treatment. Single-dose toxicity studies by intra-arterial injection of BSH-entrapped WOW were performed in rabbits and pig, and no side effects were observed. We hope to proceed to the preclinical and clinical studies for further evaluation of B compound as multidisciplinary treatments for HCC. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109202DOI Listing
September 2020

Folate-appended cyclodextrin improves the intratumoral accumulation of existing boron compounds.

Appl Radiat Isot 2020 Sep 27;163:109201. Epub 2020 Apr 27.

Radiation Oncology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan; Proton Medical Research Center, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan.

In this study, the tumor accumulation and antitumor effect of folate-modified cyclodextrin (ND201) purified with folate receptor (FR) connotated with BSH were examined. ND201 and BSH were stably bound in blood, and the mixing ratio 1:1 was most efficient. ND-BSH showed higher boron concentration (38. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109201DOI Listing
September 2020

Validation of a Monte Carlo modelled gamma camera for Lutetium-177 imaging.

Appl Radiat Isot 2020 Sep 27;163:109200. Epub 2020 Apr 27.

Department of Medical Physics, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.

This study validated a model of the Siemens Symbia T16 dual-head SPECT/CT gamma camera created using the Monte Carlo program SIMIND for Lu. The validation was done by comparing experimental and simulated gamma camera performance criteria tests for the Lu 208 keV photopeak with a medium-energy collimator. Results showed good agreement between the experimental and simulated values. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109200DOI Listing
September 2020

One-pot synthesis of sodium lauryl sulfate-loaded polyacrylonitrile solid-phase extractor for investigating the adsorption behavior of radioactive strontium(II) from aqueous solutions.

Appl Radiat Isot 2020 Sep 30;163:109198. Epub 2020 Apr 30.

Nuclear Chemistry Department, Hot Laboratories Center, Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt.

Sodium lauryl sulfate-loaded polyacrylonitrile (SLSLPAN) was synthesized in the present investigation using an in-situ one step process through gamma radiation-induced polymerization. The structure, composition, surface area and pore size and volume of the employed adsorbent were investigated by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD) and nitrogen adsorption-desorption measurements. Adsorption of radioactive strontium(II) onto SLSLPAN was studied in the pH range 3-13. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109198DOI Listing
September 2020

Analysis by Monte Carlo methods of the response of an extended-range Bonner Sphere Spectrometer.

Appl Radiat Isot 2020 Sep 29;163:109196. Epub 2020 Apr 29.

Departamento de Ingeniería Energética, ETSI Industriales, Universidad Politécnica de Madrid, José Gutiérrez Abascal 2, 28006, Madrid, Spain.

High-energy neutrons up to 230 MeV are generated as a consequence of (p,n) nuclear reactions in proton therapy facilities. The aim of this work is to evaluate the potential extension of the UPM Bonner Sphere Spectrometer (BSS) through the use of spallation materials, for its future application to determine neutron fluence spectra in such facilities. Monte Carlo methods have been used to model the response of the actual and modified spheres with the introduction of a spallation material layer, lead or copper, analyzing their response functions. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109196DOI Listing
September 2020

Tetrabutylammonium tosylate as inert phase-transfer catalyst: The key to high efficiency S2 radiofluorinations.

Appl Radiat Isot 2020 Sep 19;163:109195. Epub 2020 May 19.

N.P. Bechtereva Institute of Human Brain, Russian Academy of Science, 9, Pavlova Str, 197376, St.-Petersburg, Russia. Electronic address:

Here we describe use of the tetrabutylammonium p-toluenesulfonate (TBAOTs) as an inert phase transfer catalyst allowing high efficient aliphatic radiofluorination of labeling precursors for the preparation of common radiotracers using only 0.2-1.2 mg of the substrates. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109195DOI Listing
September 2020

The Y(n,γ) reaction: Radiative cross sections and the decay of Y.

Authors:
K S Krane

Appl Radiat Isot 2020 Sep 13;163:109191. Epub 2020 May 13.

Department of Physics, Oregon State University, Corvallis, OR, 97331, USA. Electronic address:

The activity Y was produced by radiative neutron capture on targets of mono-isotopic Y at several different reactor sites. By observing the γ rays emitted in the decay of Y, the thermal neutron cross section was deduced to be 1.02(1) mb, and the resonance integral was deduced to be 7. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109191DOI Listing
September 2020

Shielding implications on secondary radiation doses in prostate cancer treatment.

Appl Radiat Isot 2020 Sep 4;163:109163. Epub 2020 Apr 4.

Nuclear Engineering Graduate Program, Federal University of Rio de Janeiro (COPPE/UFRJ), Rio de Janeiro, Brazil; Defense Engineering Graduate Program, Military Institute of Engineering (IME), Rio de Janeiro, Brazil. Electronic address:

Medical linear accelerators (linacs) require a physical structure designed to provide adequate structural support which ensures the safety of patients, operators and the general public. During a radiotherapy session, healthy tissues are exposed to radiation, even with these safety guarantees. This unwanted exposure may increase the likelihood of developing secondary cancer. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109163DOI Listing
September 2020

Sparsity-based pulse-processor for digital α-particle spectroscopy with Si-PIN-Diode detector.

Appl Radiat Isot 2020 Sep 29;163:109245. Epub 2020 May 29.

Unidad Academica de Estudios Nucleares, Universidad Autonoma de Zacatecas Cipres 10, Fracc. La Penuela, 98068, Zacatecas, Mexico.

Nowadays, digital methods are used in nuclear detection instruments which are more popular than conventional signal processing. In this work, a digital α-particle spectrometer, compatible with the low-cost digitizers, was designed and constructed. Similar to the analog pulse-height analyses, the digital signals must also be carefully shaped. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109245DOI Listing
September 2020

Testing of Rn application for recognizing tectonic events observed on water-tube tiltmeters in underground Geodynamic Laboratory of Space Research Centre at Książ (the Sudetes, SW Poland).

Appl Radiat Isot 2020 Sep 1;163:108967. Epub 2019 Nov 1.

Space Research Centre, Polish Academy of Sciences, Bartycka 18A, Warsaw, 00-716, Poland.

Research on relationships between variation in Rn activity concentration and tectonic events recorded using the instruments of the Geodynamic Laboratory of SRC PAS at Książ (the Sudetes, SW Poland) had been conducted since 2014. The performed analyses of variation have demonstrated the spatial character of changes in Rn activity concentration. Their time-course is comparable in all parts of the underground laboratory. Read More

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http://dx.doi.org/10.1016/j.apradiso.2019.108967DOI Listing
September 2020

Primary standardization and determination of gamma ray emission intensities of Ho-166.

Appl Radiat Isot 2020 Jun 3;164:109237. Epub 2020 Jun 3.

Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Av. Prof. Lineu Prestes 2242, 05508-000, São Paulo, SP, Brazil.

The procedure followed by the Nuclear Metrology Laboratory (LMN) at the IPEN-CNEN/SP, in São Paulo, for the primary standardization of Ho is described. The activity of Ho was determined by the efficiency extrapolation technique applied to a 4πβ(PC)-γ coincidence system using a gas flow proportional counter in 4π geometry coupled to a 76 × 76 mm NaI(Tl) crystal. The results for the γ-rays intensities at 80. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109237DOI Listing

Suitability of boric acid as a boron drug for boron neutron capture therapy for hepatoma.

Appl Radiat Isot 2020 May 30;164:109254. Epub 2020 May 30.

Institute of Nuclear Engineering and Science, National Tsing Hua University, Hsinchu, Taiwan; Nuclear Science and Technology Development Center, National Tsing Hua University, Hsinchu, Taiwan. Electronic address:

Hepatoma is the second leading cause of cancer death worldwide. Due to the poor outcomes of patients with late diagnosis, newer treatments for hepatoma are still needed. As an emerging therapy, boron neutron capture therapy (BNCT) may be an effective solution in hepatoma management. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109254DOI Listing

The primary system for measurement of beta emitting radioactive gases at KRISS.

Appl Radiat Isot 2020 Jun 6;164:109238. Epub 2020 Jun 6.

Department of Physics, Kyungpook National University, Daegu, 41566, South Korea.

Korea Research Institute of Standards and Science (KRISS) is developing a length-compensated proportional counting (LCPC) system as a primary system for standardization of beta emitting radioactive gases. The pilot experiment was performed with Kr and the optimized high voltage and pressure were found to be 1700 V and 0.203 MPa, respectively. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109238DOI Listing

Chemical purification of Ag from isobaric impurity Cd by solid phase extraction chromatography: a proof of concept study.

Appl Radiat Isot 2020 Jun 9;164:109263. Epub 2020 Jun 9.

Department of Chemical Sciences, University of Padova, Via Marzolo 1, 35131, Padova, Italy. Electronic address:

Silver-111 (Ag, t = 7.47 d) is a β emitter suitable for targeted cancer therapy due to favourable decay properties. The production of no-carrier added Ag via Isotope Separation On-Line (ISOL) technique is being investigated at the Legnaro National Laboratories of the Italian Institute of Nuclear Physics (ISOLPHARM project). Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109263DOI Listing

Difference in BPA uptake between glioma stem-like cells and their cancerous cells.

Appl Radiat Isot 2020 Jun 3;164:109234. Epub 2020 Jun 3.

Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. Electronic address:

Tumor sphere-forming (TS) glioma stem cells and cancerous TS cells were analyzed in vivo and in vitro. The boron concentration in murine TS tumors was higher than normal tissue. The boron concentration at 24 h was 0. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109234DOI Listing

Comparison of digital coincidence modules used at POLATOM and PTB for TDCR and 4πβ(LS)-γ coincidence counters.

Appl Radiat Isot 2020 Jun 3;164:109231. Epub 2020 Jun 3.

National Centre for Nuclear Research Radioisotope Centre POLATOM (POLATOM), Andrzeja Sołtana 7, 05-400, Otwock, Poland.

Activity measurements of H, Am and Co solutions were performed to compare digital coincidence modules used at PTB and POLATOM for TDCR and 4πβ(LS)-γ coincidence counting. The activities determined with various coincidence modules connected in parallel to the same counter at PTB were found to be consistent. Observed discrepancies caused by differences in the coincidence resolving time did not exceed 0. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109231DOI Listing

Development of a high-sensitivity radon monitor for a radon calibration system at KRISS.

Appl Radiat Isot 2020 Jun 10;164:109228. Epub 2020 Jun 10.

Korea Research Institute of Standards and Science (KRISS), Daejeon, 34113, Republic of Korea; University of Science & Technology (UST), Daejeon, 34113, Republic of Korea.

A radon calibration system is being developed with a high-sensitivity radon detector using electrostatic collection and an alpha spectrometer. Eight radon cells, each with a volume of 1.354 L, are integrated to achieve a high-sensitivity radon monitor with a total detector volume of 10. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109228DOI Listing

Hexavalent lactoside labeled with [F]AlF for PET imaging of asialoglycoprotein receptor.

Appl Radiat Isot 2020 Aug 25;162:109199. Epub 2020 Apr 25.

Isotope Application Division, Institute of Nuclear Energy Research, Taoyuan City, Taiwan. Electronic address:

Several methods have been developed to label compounds with F. However, in general these are laborious and require a multistep synthesis. A method based on the chelation of F-aluminum fluoride ([F]AlF) by 1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA) was developed recently. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109199DOI Listing
August 2020
1.056 Impact Factor

Improvement of 6-gingerol production in ginger rhizomes (Zingiber officinale Roscoe) plants by mutation breeding using gamma irradiation.

Appl Radiat Isot 2020 Aug 27;162:109193. Epub 2020 Apr 27.

Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, 33 EL Bohouth St., Dokki, Giza, P.O.12622, Egypt. Electronic address:

Ginger (Zingiber officinale Roscoe) is a valuable culinary and medicinal plant. The compound 6-gingerol is the main gingerol in ginger rhizomes and it possesses interesting pharmacological and physiological properties. Mutation breeding involved using low doses of gamma radiation (5-30 Gy) to increase the genetic variability in ginger rhizomes (M1 generation). Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109193DOI Listing

Simultaneous measurements of the molar radioactivity, radiochemical purity and chemical impurity in the [C]choline injection using radio-HPLC with a corona-charged aerosol detector.

Appl Radiat Isot 2020 Aug 27;162:109192. Epub 2020 Apr 27.

Department of Advanced Nuclear Medicine Sciences, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, 263-8555, Japan.

[C]choline has a weak UV absorption chromophore, and it is challenging to detect less than 1 μg/mL choline using radio-HPLC-UV. In this study, we established an analytical procedure of [C]choline using the radio-HPLC coupled with the corona-charged aerosol detector. As a result, we achieved more than 100 GBq/μmol (over 0. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109192DOI Listing

Radiosynthesis of a carbon-11 labeled PDE5 inhibitor [C]TPN171 as a new potential PET heart imaging agent.

Appl Radiat Isot 2020 Aug 25;162:109190. Epub 2020 Apr 25.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 1345 West, 16th Street, Room 208, Indianapolis, IN, 46202, USA. Electronic address:

To develop PET tracers for imaging of heart disease, a new carbon-11 labeled potent and selective PDE5 inhibitor [C]TPN171 ([C]9) has been synthesized. The reference standard TPN171 (9) and its corresponding precursor desmethyl-TPN171 (11) were synthesized from methyl 3-oxovalerate and 2-hydroxybenzonitrile in 9 and 10 steps with 31% and 25% overall chemical yield, respectively. The radiotracer [C]TPN171 was prepared from desmethyl-TPN171 with [C]CHOTf through N-C-methylation and isolated by HPLC purification followed by SPE formulation in 45-55% radiochemical yield, based on [C]CO and decay corrected to EOB. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109190DOI Listing
August 2020
1.056 Impact Factor

Study on acrylate peelable nuclear detergent for film formation at low temperature.

Appl Radiat Isot 2020 Aug 26;162:109187. Epub 2020 Apr 26.

National Defence Engineering Institute, Beijing, People's Republic of China.

The human handling of radioactive contamination on the surface of nuclear facilities has become an important issue in the development of nuclear industry. In order to solve the poor film-forming of nuclear detergent in low temperature, a new type low temperature film-forming peelable nuclear decontaminant was proposed. The acrylate copolymers were developed by solution polymerization of acrylic monomers in the mass ratio of BA (butyl acrylate): MMA (methyl methacrylate): AA (acrylic acid): EA (ethyl acetate) is equal to 50:45:5:100 considering different proportioning methods and reaction temperature. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109187DOI Listing

Dosimetric properties of LiBO:Cu,Ag,P solid detector.

Appl Radiat Isot 2020 Aug 9;162:109174. Epub 2020 Apr 9.

Instituto Nacional de Investigaciones Nucleares, Carretera México-Toluca S/N, C.P. 52750, Ocoyoacac, Mexico.

This work presents results obtained following the preparation of lithium borate by the chemical reaction between lithium carbonate (LiCO) and boric acid (HBO), doping the host salt of lithium borate (LiBO) with ions of copper, silver and phosphorus. With the obtained material dosimeters were produced in sintered pellet form which were exposed by gamma radiation that emitted from Co source. The highest sensitivity was found for the sample of LiBO:Cu,Ag,P (in pellet form) with 0. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109174DOI Listing

Seasonal variation of the S-index as it relates to the concentration of Rn inside a bunker that stores radioactive material.

Appl Radiat Isot 2020 Aug 9;162:109173. Epub 2020 Apr 9.

Pedagogical and Technological University of Colombia, Tunja, Boyacá, Colombia. Electronic address:

In this work, the seasonal variation of the concentration of radon in soil and its contribution to concentrations inside of a bunker used for the storage and operation of radioactive material was studied. The measurements obtained inside and outside of the installation allowed establish a method for the calculation of the diffusion coefficient for the concrete, variable that directly influences the concentration of radon gas inside of the bunker. With the obtained results of the gamma dose rate and the concentration of radon inside the bunker, the S-index was calculated in order to determine whether the bunker would require some remediation process. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109173DOI Listing

Design of optimal digital filter and digital signal processing for a CdZnTe high resolution gamma-ray system.

Appl Radiat Isot 2020 Aug 8;162:109171. Epub 2020 Apr 8.

ULS Co., Ltd., Daejeon, 34186, Republic of Korea.

We have developed an online digital signal processing system based on an FPGA. The system consists of pile-up rejection, baseline restorer, peak detection and pole-zero cancellation for evaluation of deposited energy in the detector. The shaping algorithm employed is a Moving Window Deconvolution (MWD) to shape digitized data into a trapezoidal form. Read More

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http://dx.doi.org/10.1016/j.apradiso.2020.109171DOI Listing