1,069,349 results match your criteria Applied Physics B-lasers And Optics[Journal]


Survival Following Cytoreductive Nephrectomy: A Comparison of Existing Prognostic Models.

BJU Int 2020 Jul 4. Epub 2020 Jul 4.

The University of Texas, M.D. Anderson Cancer Center, Department of Urology, USA.

Objective: To validate models currently used to predict metastatic renal cell carcinoma (mRCC) outcomes in a cohort of patients undergoing cytoreductive nephrectomy (CN).

Patients And Methods: Ten renal cell carcinoma (RCC) prognostic models (International Metastatic RCC Database Consortium [IMDC]; Memorial Sloan Kettering Cancer Center [MSKCC]; Culp; Leibovich; University of California at Los Angeles Integrated Staging System [UISS]; Stage, Size, Grade, and Necrosis [SSIGN]; Yaycioglu; Karakiewicz; Cindolo; and Margulis) were chosen based on clinical relevance and use in clinical trial design. Model validation was performed using patients who underwent CN at a single institution between 2005 and 2017 and model discrimination (ability to select patients at risk of death) was assessed. Read More

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http://dx.doi.org/10.1111/bju.15160DOI Listing

Therapeutic ultrasound for chronic low back pain.

Cochrane Database Syst Rev 2020 Jul 5;7:CD009169. Epub 2020 Jul 5.

Department of Orthopedics, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.

Background: This is an update of a Cochrane Review published in 2014. Chronic non-specific low back pain (LBP) has become one of the main causes of disability in the adult population around the world. Although therapeutic ultrasound is not recommended in recent clinical guidelines, it is frequently used by physiotherapists in the treatment of chronic LBP. Read More

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http://dx.doi.org/10.1002/14651858.CD009169.pub3DOI Listing

Magnesium bioavailability of dried and thinly shaved Kombu in rats.

J Sci Food Agric 2020 Jul 5. Epub 2020 Jul 5.

Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto, 606-8502, Japan.

Background: Kombu has highly bioavailable magnesium (Mg) compared to other edible seaweeds, probably because Kombu contains a factor enhancing Mg absorption. However, a considerable amount of Mg is lost during industrial and cooking processes of Kombu. We hypothesized that thinly shaved Kombu (TSK), a Japanese traditional Kombu product, is a suitable Mg source for daily diets because TSK hardly loses Mg during processing. Read More

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http://dx.doi.org/10.1002/jsfa.10639DOI Listing

Trend in health-related quality of life and health utility and their decrements due to non-communicable diseases and risk factors: analysis of four population-based surveys between 1998 and 2015.

Qual Life Res 2020 Jul 4. Epub 2020 Jul 4.

Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Rm 1-01, 1/F, Jockey Club Building for Interdisciplinary Research, 5 Sassoon Road, Pokfulam, Hong Kong SAR, China.

Purpose: To revisit the population norms of health-related quality of life (HRQoL) and health utility for the Hong Kong general population, compare these scores over past health surveys, and assess the association of scores with non-communicable diseases (NCDs) and their risk factors.

Methods: HRQoL data measured by the standard Short Form 12 Health Survey-version 2 (SF-12v2) were extracted from the surveys in 1998, 2003/2004, 2008/2009 and 2014/2015. SF-12v2 data were mapped to the Short-form 6-dimension (SF-6D) preference-based measure to generate the health utility scores. Read More

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http://dx.doi.org/10.1007/s11136-020-02560-zDOI Listing

Spatial-temporal variability of aerosol sources based on chemical composition and particle number size distributions in an urban settlement influenced by metallurgical industry.

Environ Sci Pollut Res Int 2020 Jul 5. Epub 2020 Jul 5.

Department of Public Health Sciences, University of Rochester Medical Center, 265 Crittenden Boulevard, Rochester, NY, 14642-0708, USA.

The Moravian-Silesian region of the Czech Republic with its capital city Ostrava is a European air pollution hot spot for airborne particulate matter (PM). Therefore, the spatiotemporal variability assessment of source contributions to aerosol particles is essential for the successful abatement strategies implementation. Positive Matrix Factorization (PMF) was applied to highly-time resolved PM chemical composition (1 h resolution) and particle number size distribution (PNSD, 14 nm - 10 μm) data measured at the suburban (Ostrava-Plesná) and urban (Ostrava-Radvanice) residential receptor sites in parallel during an intensive winter campaign. Read More

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http://dx.doi.org/10.1007/s11356-020-09694-0DOI Listing

Traffic noise prediction model of an Indian road: an increased scenario of vehicles and honking.

Environ Sci Pollut Res Int 2020 Jul 4. Epub 2020 Jul 4.

CSIR-NEERI, Nagpur, India.

Noise is considered as an underrated and underemphasized pollutant in contrast to other pollutants of the environment. Due to the non-acute response of health effects, people are not vigilant towards consequences regarding noise pollution. The expansion of the transportation industry is contributing towards the increment in the public and private vehicular volume which causes an increment in noise pollution. Read More

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http://dx.doi.org/10.1007/s11356-020-09923-6DOI Listing

The effects of a short-term exposure to propiconazole in zebrafish (Danio rerio) embryos.

Environ Sci Pollut Res Int 2020 Jul 4. Epub 2020 Jul 4.

Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China.

Propiconazole (PCZ) is a widely used fungicide around the world and was frequently detected in surface waters, which would pose risk to aquatic organisms. Previous studies indicated that PCZ has high toxicity to different kinds of fish. However, most of the studies focus on the toxicity and mechanisms of PCZ to adult fish, the potential toxicity mechanism of PCZ to fish embryos is still poorly understood. Read More

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http://dx.doi.org/10.1007/s11356-020-09968-7DOI Listing

Strategies for applying gray water effluent on ornamental sunflower crops.

Environ Sci Pollut Res Int 2020 Jul 4. Epub 2020 Jul 4.

Center for Agrarian Sciences, Federal Rural University of the Semiarid, Mossoró, Brazil.

In a context of scarcity of good quality water, reuse is a mandatory practice to increase water availability, thus allowing the exploitation of more cropland. Although several studies have evaluated the hydric potential of domestic gray water to promote the economic and environmental sustainability of agriculture, the focus of this study was to evaluate the application of this effluent on an ornamental plant, the sunflower. The experiment was conducted in a protected environment using a completely randomized block design with split plots and four replicates. Read More

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http://dx.doi.org/10.1007/s11356-020-09200-6DOI Listing

On the three-objective static unconstrained leaf sequencing in IMRT.

Med Biol Eng Comput 2020 Jul 4. Epub 2020 Jul 4.

Department of Informatics and Applied Mathematics, Federal University of Rio Grande do Norte, Natal, RN, Brazil.

Algorithms are an essential part of radiation therapy planning, which includes three optimizations problems: beam angle configuration, fluence map, and realization. This study addresses the third one, also called the leaf sequencing problem, which arises for each chosen irradiation angle, given the optimized fluence map. It consists in defining a sequence of configurations of a device (called multileaf collimator) that correctly delivers radiation to the patient. Read More

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http://dx.doi.org/10.1007/s11517-020-02210-zDOI Listing

Menthol as an Ergogenic Aid for the Tokyo 2021 Olympic Games: An Expert-Led Consensus Statement Using the Modified Delphi Method.

Sports Med 2020 Jul 4. Epub 2020 Jul 4.

Centre for Sport Science and Human Performance, Waikato Institute of Technology, Hamilton, 3200, New Zealand.

Introduction: Menthol topical application and mouth rinsing are ergogenic in hot environments, improving performance and perception, with differing effects on body temperature regulation. Consequently, athletes and federations are beginning to explore the possible benefits to elite sport performance for the Tokyo 2021 Olympics, which will take place in hot (~ 31 °C), humid (70% RH) conditions. There is no clear consensus on safe and effective menthol use for athletes, practitioners, or researchers. Read More

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http://dx.doi.org/10.1007/s40279-020-01313-9DOI Listing

Ischemia and outcome prediction by cardiac CT based machine learning.

Int J Cardiovasc Imaging 2020 Jul 4. Epub 2020 Jul 4.

Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Heart & Vascular Center, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Drive, Charleston, SC, 29425-2260, USA.

Cardiac CT using non-enhanced coronary artery calcium scoring (CACS) and coronary CT angiography (cCTA) has been proven to provide excellent evaluation of coronary artery disease (CAD) combining anatomical and morphological assessment of CAD for cardiovascular risk stratification and therapeutic decision-making, in addition to providing prognostic value for the occurrence of adverse cardiac outcome. In recent years, artificial intelligence (AI) and, in particular, the application of machine learning (ML) algorithms, have been promoted in cardiovascular CT imaging for improved decision pathways, risk stratification, and outcome prediction in a more objective, reproducible, and rational manner. AI is based on computer science and mathematics that are based on big data, high performance computational infrastructure, and applied algorithms. Read More

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http://dx.doi.org/10.1007/s10554-020-01929-yDOI Listing

Whole exome sequencing identifies novel compound heterozygous pathogenic variants in the MYO15A gene leading to autosomal recessive non-syndromic hearing loss.

Mol Biol Rep 2020 Jul 4. Epub 2020 Jul 4.

Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Autosomal recessive non-syndromic hearing loss (ARNSHL) is a highly heterogeneous disease, for which more than 70 genes have been identified. MYO15A mutations have been reported to cause congenital severe-to-profound HL. In this study, we applied the whole exome sequencing (WES) to find the cause of HL in an Iranian family. Read More

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http://dx.doi.org/10.1007/s11033-020-05618-wDOI Listing

β-Cyclodextrin coated porous Pd@Au nanostructures with enhanced peroxidase-like activity for colorimetric and paper-based determination of glucose.

Mikrochim Acta 2020 Jul 4;187(8):425. Epub 2020 Jul 4.

Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, Anhui, 230009, People's Republic of China.

β-cyclodextrin-functionalized porous Pd@Au nanostructures (β-CD-Pd@Au) with intrinsic and enhanced peroxidase-like activity were successfully synthesized by a two-step method. The synthesized β-CD-Pd@Au can efficiently catalyze the oxidation of various substrates, such as 3,3',5,5'-tetramethylbenzidine (TMB), mixture of 4-amino antipyrine (4-AAP) and 3,5-dichloro-2-hydroxy acid sodium (DHBS) (4-AAP/DHBS), and mixture of 4-AAP and N-Ethyl-N-(3-sulfopropyl)-3-methyl-aniline sodium salt (TOPS) (4-AAP/TOPS), by HO to generate visual blue, purple, and pink color, respectively. The UV-vis absorbance peak of the three β-CD-Pd@Au catalyzed the chromogenic reaction system located at 650 nm, 510 nm, and 550 nm, respectively. Read More

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http://dx.doi.org/10.1007/s00604-020-04410-8DOI Listing

Comparative transcriptomic and physiological analyses of contrasting hybrid cultivars ND476 and ZX978 identify important differentially expressed genes and pathways regulating drought stress tolerance in maize.

Genes Genomics 2020 Jul 4. Epub 2020 Jul 4.

Department of Crop Genetics and Breeding, College of Agronomy, Hebei Agricultural University, Baoding, 071001, China.

Background: Drought is the major abiotic stress factor that negatively influences growth and yield in cereal grain crops such as maize (Zea mays L.). A multitude of genes and pathways tightly modulate plant growth, development and responses to environmental stresses including drought. Read More

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http://dx.doi.org/10.1007/s13258-020-00962-4DOI Listing

Age is not a risk factor in survival of severely ill patients with co-morbidities in a medical intensive care unit.

Ir J Med Sci 2020 Jul 4. Epub 2020 Jul 4.

Department of Internal Medicine, Nephrology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.

Background: The individuals over 65 years old constitute an important patient population of medical intensive care units (ICUs).

Aim: To evaluate the risk factors for mortality in a medical ICU consisting a group of patients with a large number of co-morbidities.

Methods: This is a retrospective study involving patients who were followed for more than 48 h. Read More

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http://dx.doi.org/10.1007/s11845-020-02298-0DOI Listing

Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome - a diagnostic in vitro tissue remodeling platform.

J Exp Orthop 2020 Jul 4;7(1):48. Epub 2020 Jul 4.

Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Building 15, Groene Loper, Gemini-Zuid 4.12, PO Box 513, 5600MB, Eindhoven, The Netherlands.

Purpose: Upon anterior cruciate ligament (ACL) rupture, reconstruction is often required, with the hamstring tendon autograft as most widely used treatment. Post-operative autograft remodeling enhances graft rupture risk, which occurs in up to 10% of the patient population, increasing up to 30% of patients aged under 20 years. Therefore, this research aimed to identify potential biological predictors for graft rupture, derived from patient-specific tissue remodeling-related cell properties in an in vitro micro-tissue platform. Read More

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http://dx.doi.org/10.1186/s40634-020-00266-2DOI Listing

Agent-based modelling and parameter sensitivity analysis with a finite-element method for skin contraction.

Biomech Model Mechanobiol 2020 Jul 4. Epub 2020 Jul 4.

Delft Institute of Applied Mathematics, Delft University of Technology, Van Mourik Broekmanweg 6, 2628 XE, Delft, The Netherlands.

In this paper, we extend the model of wound healing by Boon et al. (J Biomech 49(8):1388-1401, 2016). In addition to explaining the model explicitly regarding every component, namely cells, signalling molecules and tissue bundles, we categorized fibroblasts as regular fibroblasts and myofibroblasts. Read More

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http://dx.doi.org/10.1007/s10237-020-01354-zDOI Listing

Proton pencil-beam scanning radiotherapy in the treatment of nasopharyngeal cancer: dosimetric parameters and 2-year results.

Eur Arch Otorhinolaryngol 2020 Jul 4. Epub 2020 Jul 4.

Department of Medical Biophysics and Informatics, 3rd Faculty of Medicine, Charles University, Praha 10 Ruská 87, 100 00, Prague, Czech Republic.

Objectives:  Patients with nasopharyngeal cancer are candidates for proton radiotherapy due to large and comprehensive target volumes, and the necessity for sparing of healthy tissues. The aim of this work is to evaluate treatment outcome and toxicity profile of patients treated with proton pencil-beam scanning radiotherapy.

Materials And Methods:  Between Jan 2013 and June 2018, 40 patients were treated for nasopharyngeal cancer (NPC) with IMPT (proton radiotherapy with modulated intensity). Read More

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http://dx.doi.org/10.1007/s00405-020-06175-5DOI Listing

COVID-19 testing.

Eur Heart J 2020 Jul 5. Epub 2020 Jul 5.

Applied Clinic Sciences and Biotechnology Department, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1093/eurheartj/ehaa483DOI Listing

The role of school characteristics in pre-legalization cannabis use change among Canadian youth: implications for policy and harm reduction.

Health Educ Res 2020 Jul 5. Epub 2020 Jul 5.

School of Public Health and Health Systems, University of Waterloo, 200 University Avenue, Waterloo, ON N2L 3G1, Canada.

Reducing youth cannabis use in Canada is a public health priority with schools of interest as a potential modifier of behavior and as a venue for prevention programming. This work aimed to provide a basis for future policy and programming by evaluating pre-legalization cannabis use change patterns in schools and the impact of school characteristics on these patterns. Average rates of cannabis use behavior change (initiation, escalation, reduction, cessation) were collected from 88 high schools located in Ontario and Alberta, Canada participating in the COMPASS prospective cohort study. Read More

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http://dx.doi.org/10.1093/her/cyaa018DOI Listing

Association between PD-L1 Expression and the Prognosis and Clinicopathologic Features of Renal Cell Carcinoma: A Systematic Review and Meta-Analysis.

Urol Int 2020 Jul 3:1-9. Epub 2020 Jul 3.

Department of Urology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China,

The expression of programmed cell death-ligand 1 (PD-L1) and its correlation with the prognosis and clinicopathologic features of renal cell carcinoma (RCC) remain controversial to date. Concerning this issue, we had conducted a meta-analysis of relevant studies searched in the Web of Science, PubMed, EMBASE, and Cochrane Library databases. The Newcastle-Ottawa quality assessment scale was applied to assess the quality of the included studies. Read More

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http://dx.doi.org/10.1159/000506296DOI Listing

Work-focused therapy for common mental disorders: A naturalistic study comparing an intervention group with a waitlist control group.

Work 2020 Jul 1. Epub 2020 Jul 1.

Diakonhjemmet Hospital, Oslo, Norway.

Background: Common mental disorders (CMD) are leading causes of sickness absence. Treatments for CMD that both reduce symptoms and support work participation urgently need to be developed.

Objective: Determine the potential effects of work-focused therapy combining work interventions with either meta cognitive therapy or cognitive behavioural therapy (W-MCT/CBT) for patients with CMD on sick leave. Read More

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http://dx.doi.org/10.3233/WOR-203208DOI Listing

Roadmap for the development of a resilience indicator system for protection and civil defense organizations: A literature review of the evidence.

Work 2020 Jul 1. Epub 2020 Jul 1.

Comissão Nacional de Energia Nuclear, Instituto de Engenharia Nuclear, Cidade Universitária, Ilha do Fundão, Rio de Janeiro, Brazil.

Background: Disasters are the result of adverse events that cause human, material, environmental, and economic and social damage. To deal with disaster management, prevention, response, and recovery organizations need a system of indicators to measure their resilience.

Objective: Develop a road map to select indicators of organizational, institutional and governmental resilience to be applied to evaluate the resilience of public Protection and Civil Defense Organizations (PCDOs) of developing countries. Read More

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http://dx.doi.org/10.3233/WOR-203201DOI Listing

Effects of viewing distance on ocular vestibular evoked myogenic potentials (oVEMPs) for air- and bone-conducted stimuli at multiple sites.

J Vestib Res 2020 Jun 27. Epub 2020 Jun 27.

Department of Neurology, Prince of Wales Hospital, Randwick, Sydney, NSW, Australia.

Background: The ocular vestibular evoked myogenic potential is otolith-dependent and has been suggested to be a manifestation of the linear vestibulo-ocular reflex (L-VOR). A characteristic feature of the translational LVOR (t-LVOR) is its dependence on the distance of a target.

Objective: To assess if viewing distance affects amplitude and latency properties of the ocular vestibular evoked myogenic potential (oVEMPs). Read More

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http://dx.doi.org/10.3233/VES-200705DOI Listing

Machine learning algorithms to predict early pregnancy loss after in vitro fertilization-embryo transfer with fetal heart rate as a strong predictor.

Comput Methods Programs Biomed 2020 Jun 25;196:105624. Epub 2020 Jun 25.

School of Automation, Central South University, Changsha, Hunan, 410083, China.

Background And Objective: According to previous studies, after in vitro fertilization-embryo transfer (IVF-ET) there exist a high early pregnancy loss (EPL) rate. The objectives of this study were to construct a prediction model of embryonic development by using machine learning algorithms based on historical case data, in this way doctors can make more accurate suggestions on the number of patient follow-ups, and provide decision support for doctors who are relatively inexperienced in clinical practice.

Methods: We analyzed the significance of the same type of features between ongoing pregnancy samples and EPL samples. Read More

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http://dx.doi.org/10.1016/j.cmpb.2020.105624DOI Listing

Detection of Lipase Activity in Cells by a Fluorescent Probe Based on Formation of Self-Assembled Micelles.

iScience 2020 Jun 20;23(7):101294. Epub 2020 Jun 20.

Department of Pharmacology, Qingdao University School of Pharmacy, 308 Ningxia Road, Qingdao 266071, China; Institue of Innovative Drug Discovery, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China. Electronic address:

Reliable and sensitive detection of lipase activity is essential for the early diagnosis and monitoring of acute pancreatitis or progression of digestive diseases. However, the available fluorescent probes for detection of lipase activity are only implemented in a hexane-water two-phase system due to the nature of heterogeneous catalysis of lipase, thus limiting their applications in direct imaging of lipase activity in living cells and tissues. Here we designed and synthesized a "turn on" fluorescent probe CPP based on self-assembled micelles for hydrolysis of lipase. Read More

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http://dx.doi.org/10.1016/j.isci.2020.101294DOI Listing

Interaction of RSC Chromatin Remodeling Complex with Nucleosomes Is Modulated by H3 K14 Acetylation and H2B SUMOylation In Vivo.

iScience 2020 Jun 20;23(7):101292. Epub 2020 Jun 20.

Department of Structural Biochemistry, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Stephanstrasse 7, 64295 Darmstadt, Germany. Electronic address:

Chromatin remodeling complexes are multi-subunit nucleosome translocases that reorganize chromatin in the context of DNA replication, repair, and transcription. To understand how these complexes find their target sites on chromatin, we use genetically encoded photo-cross-linker amino acids to map the footprint of Sth1, the catalytic subunit of the RSC complex, on nucleosomes in living yeast. We find that H3 K14 acetylation induces the interaction of the Sth1 bromodomain with the H3 tail and mediates the interaction of RSC with neighboring nucleosomes rather than recruiting it to chromatin. Read More

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http://dx.doi.org/10.1016/j.isci.2020.101292DOI Listing

Real-time conflict-based Bayesian Tobit models for safety evaluation of signalized intersections.

Accid Anal Prev 2020 Jul 2;144:105660. Epub 2020 Jul 2.

Department of Civil Engineering, University of British Columbia, 6250 Applied Science Lane, Vancouver, BC, V6T 1Z4, Canada. Electronic address:

The safety of signalized intersections has traditionally been evaluated at an aggregate level by relating historical collision records for several years to the annual traffic volume and the geometric characteristics of the intersection. This is a reactive and macroscopic approach that gives little insight into how important dynamic signal cycle-related variables can affect intersection safety such as the arrival type and the shock wave characteristics. The objective of this study is to develop traffic conflict-based real-time safety models for signalized intersections using several state-of-the-art techniques. Read More

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http://dx.doi.org/10.1016/j.aap.2020.105660DOI Listing

The novel approaches to classify cyclist accident injury-severity: Hybrid fuzzy decision mechanisms.

Accid Anal Prev 2020 Jul 2;144:105590. Epub 2020 Jul 2.

Adana Alparslan Turkes Science and Technology University, Faculty of Engineering, Civil Engineering Department, Adana, Turkey. Electronic address:

In this study, two novel fuzzy decision approaches, where the fuzzy logic (FL) model was revised with the C4.5 decision tree (DT) algorithm, were applied to the classification of cyclist injury-severity in bicycle-vehicle accidents. The study aims to evaluate two main research topics. Read More

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http://dx.doi.org/10.1016/j.aap.2020.105590DOI Listing

Development of a reliable bioanalytical method based on prostate specific antigen trapping on the cavity of molecular imprinted polymer towards sensing of PSA using binding affinity of PSA-MIP receptor: A novel biosensor.

J Pharm Biomed Anal 2020 Jun 26;188:113447. Epub 2020 Jun 26.

Department of Science and Technology, Physics, Electronics and Mathematics Linköping University, Sweden.

In this study, electrically-conducting poly [Toluidine Blue (PTB)] was applied as artificial receptor. It was organized by molecular imprinting approaches and via electrochemical technique for the sensitive monitoring of prostate-specific antigen (PSA). The protein-imprinted PTB was electropolymerized in a pre-formed glutaraldehyde-cysteamine (GA-Cys A) matrix on the surface of gold electrode, which significantly boosted the stability against degradation of the Molecular Imprinted Polymer (MIP) on the surface of pre-modified gold electrode. Read More

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http://dx.doi.org/10.1016/j.jpba.2020.113447DOI Listing

A new long-wavelength emission fluorescent probe for imaging biothiols with remarkable Stokes shift.

Spectrochim Acta A Mol Biomol Spectrosc 2020 Jun 27;241:118655. Epub 2020 Jun 27.

College of Pharmacy, Qiqihar Medical University, 333 Bukui Street, Qiqihar, Heilongjiang Province 161006, PR China.

By using BPMOH as the fluorophore and 2, 4-dinitrobenzenesulfonate moiety as the recognition site for thiols, a new long-wavelength emission (645 nm) fluorescent probe BPMSH with large Stokes shift (133 nm) was designed and synthesized. Probe BPMSH exhibited almost no fluorescence emission because of the PET process. When adding thiols, BPMSH could be quickly converted into BPMOH emitting a significant red fluorescence at 645 nm. Read More

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http://dx.doi.org/10.1016/j.saa.2020.118655DOI Listing

Developing a new chemosensor targeting zinc ion based on two types of quinoline platform.

Spectrochim Acta A Mol Biomol Spectrosc 2020 Jun 26;241:118652. Epub 2020 Jun 26.

Department of Fine Chemistry, SNUT (Seoul National Univ. of Sci. and Tech.), Seoul, 01811, Republic of Korea. Electronic address:

A chemosensor DQ (2-(2-(quinolin-2-yl)hydrazinyl)-N-(quinolin-8-yl)acetamide), based on two quinoline moieties, has been synthesized. DQ could detect zinc ion through fluorescence turn-on in aqueous media. Limit of detection was calculated as 0. Read More

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http://dx.doi.org/10.1016/j.saa.2020.118652DOI Listing

Multi-mode fluorescence sensing detection based on one core-shell structure quantum dots via different types of mechanisms.

Spectrochim Acta A Mol Biomol Spectrosc 2020 Jun 19;241:118630. Epub 2020 Jun 19.

Research Center for Analytical Science, State Key Laboratory of Medicinal Chemical Biology and Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin 300071, China.

Multi-target sensing completed with single chemosensor is cost-effective and pretty attractive for the analysis of multiple analytes in single sample. CdTe/CdS QDs show high fluorescence quantum yield as a probe for the sensing purpose, but only single target is often detected. Here we proposed that three kinds of different response mechanisms were realized using CdTe/CdS QDs with the simultaneous sensing of Fe, CrO, and IO as model. Read More

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http://dx.doi.org/10.1016/j.saa.2020.118630DOI Listing

Local rotation invariance in 3D CNNs.

Med Image Anal 2020 Jun 20;65:101756. Epub 2020 Jun 20.

Institute of Information Systems, University of Applied Sciences Western Switzerland (HES-SO), Sierre, Switzerland; Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.

Locally Rotation Invariant (LRI) image analysis was shown to be fundamental in many applications and in particular in medical imaging where local structures of tissues occur at arbitrary rotations. LRI constituted the cornerstone of several breakthroughs in texture analysis, including Local Binary Patterns (LBP), Maximum Response 8 (MR8) and steerable filterbanks. Whereas globally rotation invariant Convolutional Neural Networks (CNN) were recently proposed, LRI was very little investigated in the context of deep learning. Read More

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http://dx.doi.org/10.1016/j.media.2020.101756DOI Listing

The response of the mental health network of the Salamanca area to the COVID-19 pandemic: The role of the telemedicine.

Psychiatry Res 2020 Jul 1;291:113252. Epub 2020 Jul 1.

Psychiatry Service, University of Salamanca Healthcare Complex (USHC), Salamanca, Spain; Institute of Biomedicine of Salamanca (IBSAL), University of Salamanca, Salamanca, Spain; School of Nursing and Physiotherapy, University of Salamanca, Salamanca, Spain.

The COVID-19 pandemic reached world-wide causing a great impact on healthcare services. The aim of this work is to describe the response of the Mental Health Network of the Salamanca´ Area (Spain) to this crisis and the reorganization of its resources within the first 8 weeks after the state of alarm was declared. The Psychiatry Service applied a contingency plan which included the reorganization of the human resources, the closure of some of the units and the implementation of telemedicine programs along with two specific programs, namely a mental health assistance program in the context of the infection by coronavirus, and another program for homeless people. Read More

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http://dx.doi.org/10.1016/j.psychres.2020.113252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329660PMC

Simultaneous determination of seven perfluoroalkyl carboxylic acids in water samples by 2,3,4,5,6-pentafluorobenzyl bromide derivatization and gas chromatography-mass spectrometry.

Environ Pollut 2020 Jun 21;266(Pt 3):115043. Epub 2020 Jun 21.

Hebei Key Laboratory of Applied Chemistry, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, PR China. Electronic address:

A new derivatization reagent, 2,3,4,5,6-pentafluorobenzyl bromide (PFBBr), was employed to determine seven perfluoroalkyl carboxylic acids (PFCAs) simultaneously in tap water with gas chromatography-mass spectrometry (GC-MS) technique in this study. Firstly, seven PFCAs were derivatized to their corresponding esters under alkaline condition. The derivatization conditions including the amount of PFBBr and KCO, derivatization temperature and time were optimized to increase the derivatization efficiency. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.115043DOI Listing

Field test of electrokinetically-delivered thermally activated persulfate for remediation of chlorinated solvents in clay.

Water Res 2020 Jun 20;183:116061. Epub 2020 Jun 20.

School of Civil and Environmental Engineering, Water Research Centre, University of New South Wales, Sydney, NSW, 2052, Australia. Electronic address:

In situ chemical oxidation (ISCO) has demonstrated success in remediating soil and groundwater contaminated with chlorinated volatile organic compounds (CVOCs). However, its performance is often hindered in low-permeability or heterogeneous media due to an inability to effectively deliver the oxidants. This field-scale study investigated the novel approach of applying electrokinetics (EK) to enhance the delivery of persulfate in a low-permeability media and the ability of electrical resistance heating (ERH) to thermally activate the delivered persulfate. Read More

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http://dx.doi.org/10.1016/j.watres.2020.116061DOI Listing

Metaldehyde prediction by integrating existing water industry datasets with the soil and water assessment tool.

Water Res 2020 Jun 17;183:116053. Epub 2020 Jun 17.

School of Water Resources, Indian Institute of Technology Kharagpur, Kharagpur, 721302, India.

Metaldehyde (a synthetic aldehyde pesticide used globally in agriculture) has been internationally identified as an emerging contaminant of concern. This study aimed to integrate existing water industry, publicly available and purchased licensed datasets with the open-access Soil and Water Assessment Tool (SWAT), to establish if these datasets could be used to effectively model metaldehyde in river catchments. To achieve the study aim, a SWAT model was developed and calibrated for the River Medway catchment (UK). Read More

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http://dx.doi.org/10.1016/j.watres.2020.116053DOI Listing

Social cohesion, depression, and substance use severity among young men: Cross-sectional and longitudinal analyses from a Swiss cohort.

Addict Behav 2020 Jun 15;110:106510. Epub 2020 Jun 15.

Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland; La Source, School of Nursing Sciences, HES-SO University of Applied Sciences and Arts of Western Switzerland, Lausanne, Switzerland. Electronic address:

Introduction: Social cohesion, depression, and problematic substance use are intertwined and poorly understood.This study aimed to examine cross-sectional and longitudinal associations between social cohesion, depression and problematic substance use amongyoung men, age 21-25.

Methods: We used 2nd wave (t, 2012-2014, N = 6020) and 3rd wave (t, 2016-2018) data from the on-going Swiss CohortStudy on Substance Use Risk Factors (C-SURF), assessing social cohesion, depression, and severity of alcohol, nicotine and cannabis use during both waves. Read More

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http://dx.doi.org/10.1016/j.addbeh.2020.106510DOI Listing

Comprehensive analyses of the heterogeneity and prognostic significance of tumor-infiltrating immune cells in non-small-cell lung cancer: Development and validation of an individualized prognostic model.

Int Immunopharmacol 2020 Jul 2;86:106744. Epub 2020 Jul 2.

Institute of Oncology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250021, China; Department of Thoracic Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250021, China; Institute of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China. Electronic address:

Understanding the role of tumor-infiltrating immune cells (TIICs) in non-small cell lung cancer (NSCLC) is critical to finding new prognostic biomarkers and improving prognostic evaluation. Herein, we aimed to comprehensively analyze tumor-infiltrating pattern of TIICs in NSCLC and build a TIICs-associated, risk-stratification prognostic model for clinical practice. We applied CIBERSORT and ESTIMATE computational methods to analyze RNA-seq samples of 852 NSCLC patients from The Cancer Genome Atlas (TCGA). Read More

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http://dx.doi.org/10.1016/j.intimp.2020.106744DOI Listing

Health and economic impacts of air pollution induced by weather extremes over the continental U.S.

Environ Int 2020 Jul 2;143:105921. Epub 2020 Jul 2.

School of Forestry & Environmental Studies, Yale University, New Haven, CT 06511, USA.

Extreme weather events may enhance ozone (O) and fine particulate matter (PM) pollution, causing additional adverse health effects. This work aims to evaluate the health and associated economic impacts of changes in air quality induced by heat wave, stagnation, and compound extremes under the Representative Concentration Pathways (RCP) 4.5 and 8. Read More

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http://dx.doi.org/10.1016/j.envint.2020.105921DOI Listing

Design, synthesis and antimicrobial evaluation of novel glycosylated-fluoroquinolones derivatives.

Eur J Med Chem 2020 Jun 27;202:112513. Epub 2020 Jun 27.

Department of Biotechnology, Faculty of Applied Sciences, UCSI University, Kuala Lumpur, Malaysia.

Herein we report the design, synthesis and biological evaluation of structurally modified ciprofloxacin, norfloxacin and moxifloxacin standard drugs, featuring amide functional groups at C-3 of the fluoroquinolone scaffold. In vitro antimicrobial testing against various Gram-positive bacteria, Gram-negative bacteria and fungi revealed potential antibacterial and antifungal activity. Hybrid compounds 9 (MIC 0. Read More

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http://dx.doi.org/10.1016/j.ejmech.2020.112513DOI Listing

Incorporation of iron (oxyhydr)oxide nanoparticles with expanded graphite for phosphorus removal and recovery from aqueous solutions.

Chemosphere 2020 Jun 23;259:127395. Epub 2020 Jun 23.

Department of Civil and Environmental Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. Electronic address:

In this work, iron (oxyhydr)oxide nanoparticle-doped expanded graphite (IO/EG-1 and IO/EG-2) was prepared via a hydrothermal reaction and applied for the phosphorus adsorption in the aqueous solutions. The analysis of scanning electron microscopy (SEM) and X-ray diffraction (XRD) verified the successful fabrication of IO/EGs, and iron (oxyhydr)oxide nanoparticles became more crystalized according to the calcination at high temperature (IO/EG-2). The maximum adsorption capacity of IO/EG-1 was considerably higher (7. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2020.127395DOI Listing

A novel approach for rapidly measuring volatile fatty acids in anaerobic process.

Water Res 2020 Jun 12;182:115960. Epub 2020 Jun 12.

Water Research Group, Department of Civil Engineering, University of Cape Town, Cape Town, South Africa.

Volatile fatty acids (VFAs), the intermediate of the anaerobic process, are considered to be the critical, high-sensitive and reliable indicators of the process stability. Close monitoring and control of VFAs are paramount for the efficient operation of the anaerobic reactors. In this study, a buffer intensity-based mathematical model was developed, and the least square method was integrated into the model to solve the issue of non-linear fitting of the titration curve. Read More

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http://dx.doi.org/10.1016/j.watres.2020.115960DOI Listing

Metagenomic insights into aniline effects on microbial community and biological sulfate reduction pathways during anaerobic treatment of high-sulfate wastewater.

Sci Total Environ 2020 Jun 28;742:140537. Epub 2020 Jun 28.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.

For comprehensive insights into the change of sulfate reduction pathway responding to the toxic stress and the shift of microbial community and performance of sulfate reduction, we built a laboratory-scale expanded granular sludge bed reactor (EGSB) treating high-sulfate wastewater with elevated aniline concentrations from 0 to 480 mg/L. High-throughput sequencing and metagenomic approaches were applied to decipher the molecular mechanisms of sulfate reduction under aniline stress through taxonomic and functional profiles. The increasing aniline in the anaerobic system induced the accumulation of volatile fatty acids (VFA), further turned the bioreactor into acidification, which was the principal reason for the deterioration of system performance and finally resulted in the accumulation of toxic free sulfide. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.140537DOI Listing

Simultaneous removal of para-arsanilic acid and the released inorganic arsenic species by CuFe2O4 activated peroxymonosulfate process.

Sci Total Environ 2020 Jun 29;742:140587. Epub 2020 Jun 29.

School of Environmental Science and Engineering, Suzhou University of Science and Technology, Suzhou 215009, China.

para-arsanilic acid (p-ASA), as a major phenylarsonic feed additive, was used annually in many countries. Once it enters the water environment, p-ASA would be transformed into hypertoxic inorganic arsenic species, causing severe arsenic pollution. In this study, magnetic copper ferrite (CuFeO) was applied to activate peroxymonosulfate (PMS) for p-ASA removal and synchronous control of the released inorganic arsenic species. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.140587DOI Listing

Transcriptome analysis of the Sepia pharaonis: Identification of low salinity stress-related information and microsatellite markers.

Comp Biochem Physiol Part D Genomics Proteomics 2020 Jun 27;35:100705. Epub 2020 Jun 27.

Key Laboratory of Applied Marine Biotechnology, Ministry of Education, Ningbo University, Ningbo City, Zhejiang Province 315832, PR China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo City, Zhejiang Province 315832, PR China.

Sepia pharaonis has great commercial value for aquaculture. However, it is sensitive to salinity fluctuations and lacking in genomic information. The present work utilized high-throughput transcriptome sequencing to assess the effect of low salinity (22. Read More

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http://dx.doi.org/10.1016/j.cbd.2020.100705DOI Listing

Investigating the roles of the conserved Cu-binding residues on Brucella FtrA in producing conformational stability and functionality.

J Inorg Biochem 2020 Jun 23;210:111162. Epub 2020 Jun 23.

Department of Chemistry, Amity Institute of Applied Sciences, Amity University Kolkata, WB, 700135, India.

Brucella is a zoonotic pathogen requiring iron for its survival and acquires this metal through the expression of several high-affinity uptake systems. Of these, the newly discovered ferrous iron transporter, FtrABCD, is proposed to take part in ferrous iron uptake. Sequence homology shows that, FtrA, the proposed periplasmic ferrous-binding component, is a P19-type protein (a periplasmic protein from C. Read More

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http://dx.doi.org/10.1016/j.jinorgbio.2020.111162DOI Listing

Neurological impact of emboli during adult cardiac surgery.

J Neurol Sci 2020 Jun 27;416:117006. Epub 2020 Jun 27.

Department of Cardiovascular Sciences, University of Leicester, Leicester LE2 7LX, UK; Leicester Biomedical Research Centre, Glenfield Hospital, Leicester LE3 9QP, UK; University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK. Electronic address:

Objectives: This study draws on advances in Doppler ultrasound bubble sizing to investigate whether high volumes of macro-bubbles entering the brain during cardiac surgery increase the risk of new cerebral microbleeds (CMBs), ischemic MR lesions, or post-operative cognitive decline (POCD).

Methods: Transcranial Doppler (TCD) ultrasound recordings were analysed to estimate numbers of emboli and macrobubbles (>100 μm) entering the brain during cardiac surgery. Logistic regression was used to explore the hypothesis that emboli characteristics affect the incidence of new brain injuries identified through pre- and post-operative MRI and neuropsychological testing. Read More

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http://dx.doi.org/10.1016/j.jns.2020.117006DOI Listing

Stable biomarker identification for predicting schizophrenia in the human connectome.

Neuroimage Clin 2020 Jun 19;27:102316. Epub 2020 Jun 19.

Institute for Information and Communication Technologies, Electronics and Applied Mathematics (ICTEAM), Université catholique de Louvain, Louvain-la-Neuve, Belgium; Center for Operations Research and Econometrics (CORE), Université catholique de Louvain, Louvain-la-Neuve, Belgium. Electronic address:

Schizophrenia, as a psychiatric disorder, has recognized brain alterations both at the structural and at the functional magnetic resonance imaging level. The developing field of connectomics has attracted much attention as it allows researchers to take advantage of powerful tools of network analysis in order to study structural and functional connectivity abnormalities in schizophrenia. Many methods have been proposed to identify biomarkers in schizophrenia, focusing mainly on improving the classification performance or performing statistical comparisons between groups. Read More

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http://dx.doi.org/10.1016/j.nicl.2020.102316DOI Listing
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