958,364 results match your criteria Applied Mathematics-a Journal Of Chinese Universities Series B[Journal]


Chemoradiation induces epithelial-to-mesenchymal transition in esophageal adenocarcinoma.

Int J Cancer 2019 Apr 24. Epub 2019 Apr 24.

Department of Medical Oncology, Amsterdam, The NetherlandsRadiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam.

Multimodality treatment has advanced the outcome of esophageal adenocarcinoma (EAC), but overall survival remains poor. Therapeutic pressure activates effective resistance mechanisms and we characterized these mechanisms in response to the currently used neoadjuvant treatment against EAC; carboplatin, paclitaxel and radiotherapy. We developed an in vitro approximation of this regimen and applied it to primary patient-derived cultures. Read More

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http://dx.doi.org/10.1002/ijc.32364DOI Listing

Maintenance of Integrity of Upper Facet Joints during Simulated Percutaneous Pedicle Screw Insertion Using 2D versus 3D Planning.

J Neurol Surg A Cent Eur Neurosurg 2019 Apr 24. Epub 2019 Apr 24.

Department of Neurosurgery, University of Mainz, Mainz, Germany.

Background:  No studies have directly and quantitatively compared two-dimensional (2D) and three-dimensional (3D) planning as applied during conventional percutaneous or navigated percutaneous pedicle screw placement.

Study Aims:  This lumbar pedicle-based stabilization simulation study aimed to investigate the risk of upper facet joint violation (FJV) during posterior percutaneous pedicle screw placement with conventional 2D planning of screw implantation (as a model for fluoroscopically guided screws) compared with 3D planning (as used with navigation techniques).

Methods:  The placement of monosegmental lumbar pedicle screws using the data sets of 250 consecutive patients was simulated. Read More

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http://dx.doi.org/10.1055/s-0039-1681042DOI Listing

Effect of indium doping on motions of -prismatic edge dislocations in wurtzite gallium nitride.

J Phys Condens Matter 2019 Apr 24. Epub 2019 Apr 24.

Department of Mining and Materials Engineering - Materials, McGill University, Rm 2140 Wong Building, 3610 University Street, Montreal, Quebec H3A 2B2, Montreal, Quebec, CANADA.

The influences of indium doping on dynamics of a-type edge dislocations along (11 ̅00)[112 ̅0] shuffle plane in wurtzite GaN have been investigated employing classical molecular dynamics (MD) simulations. The dependence of dislocation motion mode and dislocation velocity on indium doping concentration, temperature, and applied shear stress was clarified. Moreover, the simulation results were further analyzed using elastic theory of dislocation and thermal activation theory of dislocation motion, showing excellent agreement with the simulation. Read More

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http://dx.doi.org/10.1088/1361-648X/ab1bf3DOI Listing

Discretized dynamics of exchange spin wave bulk and edge modes in honeycomb nanoribbons with armchair edge boundaries.

J Phys Condens Matter 2019 Apr 24. Epub 2019 Apr 24.

Department of Theoretical Physics, Jan Dlugosz University in Czestochowa, Czestochowa, POLAND.

We develop a field theory to study the dynamics of long wavelength exchange spin wave excitations on honeycomb nanoribbons characterized by armchair edge boundaries and the Néel antiferromagnetic ordering state. Appropriate boundary conditions are established by requiring that the bulk and edge spins precess with the same frequency for any given spin wave eigenmode in these systems. A set of characteristic boundary equations, common for bulk and edge spin wave modes, are hence derived. Read More

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http://dx.doi.org/10.1088/1361-648X/ab1c2eDOI Listing

Statistical mechanical properties of sequence space determine the efficiency of the various algorithms to predict interaction energies and native contacts from protein coevolution.

Phys Biol 2019 Apr 24. Epub 2019 Apr 24.

Department of Physics, Universita degli Studi di Milano, Milano, Lombardia, ITALY.

Studying evolutionary correlations in alignments of homologous sequences by means of an inverse Potts model has proven useful to obtain residue-residue contact energies and to predict contacts in proteins. The quality of the results depend much on several choices of the detailed model and on the algorithms used. We built, in a very controlled way, synthetic alignments with statistical properties similar to those of real proteins, and used them to assess the performance of different inversion algorithms and of their variants. Read More

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http://dx.doi.org/10.1088/1478-3975/ab1c15DOI Listing

Pulp improvement of oil palm empty fruit bunches associated to solid-state biopulping and biobleaching with xylanase and lignin peroxidase cocktail produced by Aspergillus sp. LPB-5.

Bioresour Technol 2019 Apr 18;285:121361. Epub 2019 Apr 18.

Department of Agricultural Sciences and Technology, Federal University of Tocantins, CEP 7740-2970, Gurupi, TO, Brazil; Department of Bioprocess and Biotechnology Engineering, Federal University of Paraná, CEP 81531-970, Curitiba, PR, Brazil. Electronic address:

Oil palm empty fruit bunches is a lignocellulosic feedstock with biotechnological potential and thousands of tons are generated in the world each year. Filamentous fungi producing xylanases and ligninases in biopulping to obtain cellulose is a pulp improvement alternative. The enzymatic cocktail was produced in solid-state biopulping by Aspergillus sp. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.121361DOI Listing

Impact of Adjuvant Chemotherapy on Oncologic Outcomes following Radical Nephroureterectomy for Patients with pT3NanyM0 Upper Tract Urothelial Carcinoma: A retrospective cohort study.

Int J Surg 2019 Apr 21. Epub 2019 Apr 21.

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

Objective: We investigated the impact of cisplatin-based adjuvant chemotherapy (AC) on oncologic outcomes including recurrence-free survival (RFS), cancer-specific survival (CSS) and overall survival (OS) after radical nephroureterectomy (RNU) for patients with pT3NanyM0 upper tract urothelial carcinoma (UTUC).

Methods: We retrospectively reviewed 293 patients who underwent RNU for UTUC between 1995 and 2017. Clinicopathologic characteristics of patients were examined and compared according to the use of AC. Read More

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http://dx.doi.org/10.1016/j.ijsu.2019.04.013DOI Listing

Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb.

J Ethnopharmacol 2019 Apr 21:111902. Epub 2019 Apr 21.

TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China. Electronic address:

Ethnopharmacological Relevance: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by failure of spontaneous resolution of inflammation. The stem of Kadsura heteroclite (KHS) is a well-known anti-arthritic Tujia ethnomedicinal plant, which named Xuetong in folk, has long been used for the prevention and treatment of rheumatic and arthritic diseases.

Aim Of The Study: The analgesic and anti-inflammatory effects and the potential mechanisms behind such effects of KHS would be investigated by using different animal models. Read More

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http://dx.doi.org/10.1016/j.jep.2019.111902DOI Listing

Gene and Induced Pluripotent Stem Cell Therapy for Retinal Diseases.

Annu Rev Genomics Hum Genet 2019 Apr 24. Epub 2019 Apr 24.

Laboratory for Retinal Regeneration, Center for Biosystems Dynamics Research, RIKEN, Kobe, Hyogo 650-0047, Japan; email:

Given the importance of visual information to many daily activities, retinal degenerative diseases-which include both inherited conditions (such as retinitis pigmentosa) and acquired conditions (such as age-related macular degeneration)-can have a dramatic impact on human lives. The therapeutic options for these diseases remain limited. Since the discovery of the first causal gene for retinitis pigmentosa almost three decades ago, more than 250 genes have been identified, and gene therapies have been rapidly developed. Read More

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http://dx.doi.org/10.1146/annurev-genom-083118-015043DOI Listing

Enhancement of the Monolayer Tungsten-Disulfide Exciton Photoluminescence with a Two-Dimensional-Material/Air/Gallium-Phosphide In-Plane Microcavity.

ACS Nano 2019 Apr 24. Epub 2019 Apr 24.

Light-matter interaction with two-dimensional materials gained significant attention in recent years leading to the reporting of weak and strong coupling regimes, and effective nano-laser operation with various structures. Particularly, future applications involving monolayer materials in waveguide-coupled on-chip integrated circuitry and valleytronic nanophotonics require controlling, directing and optimizing photoluminescence. In this context, photoluminescence enhancement from monolayer transition-metal dichalcogenides on patterned semiconducting substrates becomes attractive. Read More

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http://dx.doi.org/10.1021/acsnano.8b09659DOI Listing

A Variational Relativistic Two-Component Complete Active Space Self-Consistent Field Method.

J Chem Theory Comput 2019 Apr 24. Epub 2019 Apr 24.

The accurate description of the electronic structure of transition metals and their compounds can be complicated by both the large number of close-lying states that often have multi-configurational nature in addition to significant relativistic effects. In order to address these challenges we present a two-component complete-active-space self-consistent field method that includes scalar relativistic effects and one-electron spin-orbit coupling during the self-consistent wave function optimization procedure. These relativistic effects are included via an "exact two-component" transformation of the solution of the one-electron modified Dirac equation. Read More

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http://dx.doi.org/10.1021/acs.jctc.9b00011DOI Listing

Optically Stimulated Artificial Synapse Based on Layered Black Phosphorus.

Small 2019 Apr 24:e1900966. Epub 2019 Apr 24.

Functional Materials and Microsystems Research Group and the Micro Nano Research Facility, RMIT University, Melbourne, VIC, 3001, Australia.

The translation of biological synapses onto a hardware platform is an important step toward the realization of brain-inspired electronics. However, to mimic biological synapses, devices till-date continue to rely on the need for simultaneously altering the polarity of an applied electric field or the output of these devices is photonic instead of an electrical synapse. As the next big step toward practical realization of optogenetics inspired circuits that exhibit fidelity and flexibility of biological synapses, optically-stimulated synaptic devices without a need to apply polarity-altering electric field are needed. Read More

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http://dx.doi.org/10.1002/smll.201900966DOI Listing

Scissor haemorrhoidectomy under perineal anaesthetic infiltration as a day case procedure - video vignette.

Colorectal Dis 2019 Apr 24. Epub 2019 Apr 24.

Departament of Surgical oncology, Institute of Oncology, Vilnius University, Clinic of Internal, Family Medicine and Oncology, Faculty of Medicine, Vilnius, Lithuania.

Hemorrhoids are common anorectal disease [1]. Patients with Grade III-IV prolapsed hemorrhoids or after failed conservative are considered for excisional hemorrhoidectomy. Surgical technique At our department all patients with Grade III or IV symptomatic hemorrhoids undergo closed (as described by Fergusson) scissor hemorrhoidectomy under perineal anesthetic infiltration [2], with removal of the two classical piles at 3 and 11. Read More

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http://dx.doi.org/10.1111/codi.14656DOI Listing

Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection.

PLoS Pathog 2019 Apr 24;15(4):e1007709. Epub 2019 Apr 24.

Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.

Norovirus infection is the leading cause of food-borne gastroenteritis worldwide, being responsible for over 200,000 deaths annually. Studies with murine norovirus (MNV) showed that protective STAT1 signaling controls viral replication and pathogenesis, but the immune mechanisms that noroviruses exploit to induce pathology are elusive. Here, we show that gastrointestinal MNV infection leads to widespread IL-1β maturation in MNV-susceptible STAT1-deficient mice. Read More

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http://dx.doi.org/10.1371/journal.ppat.1007709DOI Listing

Transcranial Doppler ultrasound in vascular cognitive impairment-no dementia.

PLoS One 2019 24;14(4):e0216162. Epub 2019 Apr 24.

Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, Italy.

Background: Although cerebral white matter lesions (WMLs) are considered as a risk factor for vascular dementia, data on their impact on cerebral hemodynamics are scarce. We test and compare transcranial Doppler (TCD) features in WML patients with or without associated cognitive impairment.

Methods: A sample of non-demented elderly patients with WMLs was consecutively recruited. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216162PLOS

Convergence in health care spending across counties in New York from 2007 through 2016.

Authors:
Mark A Zezza

PLoS One 2019 24;14(4):e0215850. Epub 2019 Apr 24.

New York State Health Foundation, New York City, New York, United States of America.

Background: One approach considered for reducing health care spending is to narrow the gap in spending between high- and low-spending areas. The goal would be to reduce spending in the high areas to similar levels achieved in areas that use health care more efficiently. This paper examined the degree to which high-spending areas remain high-spending and which types of service lead to convergence or divergence in spending in New York State. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215850PLOS

Mutational landscape of canine B-cell lymphoma profiled at single nucleotide resolution by RNA-seq.

PLoS One 2019 24;14(4):e0215154. Epub 2019 Apr 24.

Department of Comparative Biomedicine and Food Science, University of Padua, Legnaro, Padua, Italy.

The genomic landscape in human B-cell lymphoma has revealed several somatic mutations and potentially relevant germline alterations affecting therapy and prognosis. Also, mutations originally described as somatic aberrations have been shown to confer cancer predisposition when occurring in the germline. The relevance of mutations in canine B-cell lymphoma is scarcely known and gene expression profiling has shown similar molecular signatures among different B-cell histotypes, suggesting other biological mechanisms underlining differences. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215154PLOS

Adaptation of the Childbirth Experience Questionnaire (CEQ) in China: A multisite cross-sectional study.

PLoS One 2019 24;14(4):e0215373. Epub 2019 Apr 24.

Chinese Maternal and Child Health Association, Beijing, China.

Background: The childbirth experience of women represents a significant aspect of quality care. Due to the lack of a reliable Chinese language tool for assessing childbirth experiences, examples must be adapted from other countries. The aim of this study was to translate an English version of the Childbirth Experience Questionnaire (CEQ) into Chinese and adapt this tool to the Chinese context. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215373PLOS
April 2019
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Densities and drivers of sea turtle populations across Pacific coral reef ecosystems.

PLoS One 2019 24;14(4):e0214972. Epub 2019 Apr 24.

Monterey Bay Aquarium, Monterey, California, United States of America.

Sea turtle populations are often assessed at the regional to sub-basin scale from discrete indices of nesting abundance. While this may be practical and sometimes effective, widespread in-water surveys may enhance assessments by including additional demographics, locations, and revealing emerging population trends. Here, we describe sea turtle observations from 13 years of towed-diver surveys across 53 coral islands, atolls, and reefs in the Central, West, and South Pacific. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214972PLOS

The physical activity level and aerobic capacity estimation (VO2max) among the administrative staff of the Pars Special Economic Energy Zone (Assaluyeh, Iran) with different BMIs.

Horm Mol Biol Clin Investig 2019 Apr 24. Epub 2019 Apr 24.

Department of Biostatistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Background The purpose of this study was to examine the level of physical activity (PA) and maximal aerobic capacity (VO2max) among office workers of the Pars Special Economic Energy Zone in Iran with different body mass indexes (BMIs). Materials and methods This research was descriptive, and a correlation of variables was applied as its execution method. Administrative staff of two centers were randomly selected from 20 to 30 administrative centers of the Pars Special Economic Energy Zone, Assaluyeh, Iran, and included 294 male employees who were willing to participate in this research and who met the inclusion criteria (being in the age range of 20-60 years, lacking specific diseases, and who had enough physical fitness to do PA) who were purposefully selected. Read More

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http://dx.doi.org/10.1515/hmbci-2018-0080DOI Listing

Comparison of Antimicrobial Treatments Applied via Conventional or Handheld Electrostatic Spray To Reduce Shiga Toxin-Producing on Chilled Beef Outside Rounds.

J Food Prot 2019 Apr 24:862-868. Epub 2019 Apr 24.

2 Department of Animal Science, Texas A&M University, College Station, Texas 77843, USA (ORCID: https://orcid.org/0000-0002-7538-8391 [A.C.]).

Highlights: We found no advantage in the use of electrostatic spray to reduce STEC8 on cold beef. Greatest reductions in STEC8 were achieved by lactic acid with conventional spray. Lauric arginate ester was the second best antimicrobial agent at reducing STEC8. Read More

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http://dx.doi.org/10.4315/0362-028X.JFP-18-399DOI Listing

Overtones of νC≡N Vibration as a Probe of Structure of Liquid CHCN, CDCN and CClCN. Combined IR, NIR, and Raman Spectroscopic Studies with Anharmonic DFT Calculations.

J Phys Chem A 2019 Apr 24. Epub 2019 Apr 24.

The νCN band ( νC≡N) is a sensitive probe of the state of compounds with nitrile groups. Hence, physicochemical properties of acetonitrile and its derivatives have been frequently investigated by means of vibrational (IR and Raman) spectroscopy. Near-infrared (NIR) spectroscopy combined with high-level quantum mechanical calculations offers deeper physical insight into the structure of liquid nitriles, not available from the fundamental region. Read More

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http://dx.doi.org/10.1021/acs.jpca.9b02170DOI Listing

Aligning product chemistry and soil context for agronomic reuse of human-derived resources.

Environ Sci Technol 2019 Apr 24. Epub 2019 Apr 24.

Recovering human-derived nutrients from sanitation systems can offset inorganic fertilizer use and improve access to agricultural nutrients in resource-limited settings, but the agronomic value of recovered products depends upon product chemistry and soil context. Products may exacerbate already-compromised soil conditions, offer benefits beyond nutrients, or have reduced efficacy depending on soil characteristics. Using global spatial modeling, we evaluate the soil suitability of seven products (wastewater, sludge, compost, urine, ammonium sulfate, ammonium struvite, potassium struvite) and integrate this information with local recovery potential of each product from sanitation systems that will need to be installed to achieve universal coverage (referred to here as "newly-installed sanitation"). Read More

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http://pubs.acs.org/doi/10.1021/acs.est.9b00504
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http://dx.doi.org/10.1021/acs.est.9b00504DOI Listing
April 2019
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Synthesis, Crystal Structures, and Photochemical Properties of a Family of Heterometallic Titanium Oxo Clusters.

Inorg Chem 2019 Apr 24. Epub 2019 Apr 24.

State Key Laboratory of Rare Earth Resource Utilization , Changchun Institute of Applied Chemistry, Chinese Academy of Sciences , 5625 Renmin Street , Changchun , Jilin 130022 , China.

The incorporation of heterometallic atoms into the structure of titanium-oxygen nanomaterials is one of the known and effective strategies to develop new high-performance photovoltaic active materials. In this study, we have synthesized three benzoic acid-stabilized heterometallic titanium oxo clusters with the different transition metals Co, Cu, and Cd, formulated as [TiCo(μ-O)(μ-O)(CHCOO)(CHCN)]·2CHCN (1), [TiCu(μ-O)(CHCOO)] (2), and [TiCd(μ-O)(μ-O)(μ-O)(CHCOO)(CHCOOH)(CHCN)]·CHCN·CHCOOH (3), and then we characterized their structures. UV-vis spectroscopy analysis revealed an enhanced UV-vis-light absorption of those heterometallic clusters. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.9b00508DOI Listing

Selectively Metalized 2D Materials for Simple Logic Devices.

ACS Appl Mater Interfaces 2019 Apr 24. Epub 2019 Apr 24.

We herein demonstrate, for the first time, transparent, flexible, and large-area monolithic MoS2 transistors and logic gates. Each single transistor consists of only two components: a monolithic chemical vapor deposition (CVD)-grown MoS2 layer and an ion-gel gate dielectric. Additional electrode materials are not required. Read More

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http://dx.doi.org/10.1021/acsami.9b03078DOI Listing

Polymeric Emulsion Technology Applied to Tretinoin

J Drugs Dermatol 2019 Apr;18(4):s148-154

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Profiling the constituents of Dachuanxiong decoction by liquid chromatography-high resolution tandem mass spectrometry using target and nontarget data mining.

J Sep Sci 2019 Apr 24. Epub 2019 Apr 24.

Beijing Research Institute of Chinese Medicine, Beijing, P. R. China.

Comprehensive characterization of the large number of compounds existing in traditional Chinese medicines is still a great challenge. In this paper, a strategy of precursor ion selected acquisition coupled with target and nontarget data mining was established to systematically characterize the chemical constituents of traditional Chinese medicines. This strategy consisted of four steps: 1) precursor ion selected acquisition was developed to trigger additional MS/MS fragmentation reactions, especially for trace constituents; 2) in-house database of compounds was established and diagnostic characteristics were summarized; 3) compounds were identified by target and nontarget data mining; 4) compound structures were elucidated based on accurate mass matching and comparison of fragment ions, and isomers were discriminated by the intensity of fragment ions, fragmentation pattern analysis and calculated logP values. Read More

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http://dx.doi.org/10.1002/jssc.201900064DOI Listing

Observe Spatiotemporal Heterogeneity of Reactions in Solution with High-Speed Single Nanorod Rotational Sensing.

Angew Chem Int Ed Engl 2019 Apr 24. Epub 2019 Apr 24.

Tsinghua University, Department of Chemistry, Department of Chemistry, Tsinghua University, 100084, Beijing, CHINA.

We have developed a high-speed dark-field microscope to monitor the rapid rotation of single gold nanorods (AuNRs) and use it to study the spatiotemporal heterogeneity of chemical reactions in free solution. A wide range of viscosity change from 237 cP to 0.8 cP could be detected conveniently. Read More

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http://dx.doi.org/10.1002/anie.201901550DOI Listing

Systematic experimental study on quantum sieving of hydrogen isotopes in metal-amide-imidazolate frameworks with narrow 1-D channels.

Chemphyschem 2019 Apr 24. Epub 2019 Apr 24.

Max-Planck-Institut fur Intelligente Systeme, Max-Planck-Institut für Intelligente Systeme, Heisenbergstr. 3, 70569, Stuttgart, GERMANY.

Quantum sieving of hydrogen isotopes is experimentally studied in isostructural hexagonal metal-organic frameworks having 1-D channels, named IFP-1, -3, -4 and -7. Inside the channels different molecules or atoms restrict the channel diameter periodically with apertures larger (4.2 Å for IFP-1, 3. Read More

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http://dx.doi.org/10.1002/cphc.201900183DOI Listing

Pulsed EPR Dipolar Spectroscopy under the Breakdown of the High-Field Approximation: The High-Spin Iron(III) Case.

Chemistry 2019 Apr 24. Epub 2019 Apr 24.

University of Bonn, Institute of Physical and Theoretical Chemistry, Wegelerstr. 12, 53115, Bonn, GERMANY.

Pulsed EPR Dipolar Spectroscopy (PDS) offers several methods for measuring the dipolar coupling and thus the distance between electron-spin centers. Up to now, PDS measurements to metal centers were limited to ions that adhere to the high-field approximation. Here, the PDS methodology is extended to cases where the high-field approximation breaks down on the example of the high-spin Fe3+/nitroxide spin-pair. Read More

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http://dx.doi.org/10.1002/chem.201900977DOI Listing

Cryopreservation of Endangered Wild Species, Aster altaicus var. uchiyamae Kitam, Using Droplet-Vitrification Procedure.

Cryo Letters 2019 Mar/Apr;40(2):113-122

Dept. of Well-being Resources, Sunchon National University, Suncheon, 57922, Korea.

Background: Aster altaicus var. uchiyamae Kitam is an endemic and endangered species in urgent need of a comprehensive conservation strategy.

Objective: To develop an efficient cryopreservation protocol using in vitro shoot tips to complement traditional conservation approaches in case seeds are not available or insufficient for conservation programs. Read More

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Gold nanorods as a high-pressure sensor of phase transitions and refractive-index gauge.

Nanoscale 2019 Apr 24. Epub 2019 Apr 24.

Adam Mickiewicz University, Faculty of Chemistry, Umultowska 89b, 61-614 Poznań, Poland.

Gold nanorods (Au NRs), nanospheres and other nanoparticles display numerous superior physicochemical properties, such as resistance to oxidation and aggressive agents, strong enhancement of local electric field and a high absorption coefficient in the visible and near-infrared (NIR) range. The absorption peaks of surface plasmon resonance (SPR) in Au NRs are highly sensitive to their surrounding medium and to its refractive index (RI) changes. However, no applications of NRs for detecting phase transitions have been reported. Read More

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http://dx.doi.org/10.1039/c9nr02792kDOI Listing

An efficient light on-off one-pot method for the synthesis of 3-styryl coumarins from aryl alkynoates.

Org Biomol Chem 2019 Apr 24. Epub 2019 Apr 24.

College of Chemistry and Molecular Engineering, Henan Key Laboratory of Chemical Biology and Organic Chemistry, Key Laboratory of Applied Chemistry of Henan Universities, Zhengzhou University, Zhengzhou 450052, P.R. China.

An efficient one-pot stepwise method to synthesize 3-styryl-4-arylcoumarins from simple alkynoates is demonstrated. On the basis of the control experiments, a possible mechanism involving light-driven radical cyclization and Pd-catalysed cross-coupling processes for this synthesis method is proposed. The results of X-ray analysis and spectroscopy experiments prove that the substituent effect has a significant influence on the absorption and emission properties of the synthesized 3-styryl coumarins. Read More

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http://dx.doi.org/10.1039/c9ob00421aDOI Listing

Z-scheme photocatalyst systems employing Rh- and Ir-doped metal oxide materials for water splitting under visible light irradiation.

Faraday Discuss 2019 Apr 24. Epub 2019 Apr 24.

Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan. and Photocatalysis International Research Center, Research Institute for Science and Technology, Tokyo University of Science, 2641, Yamazaki, Noda-shi, Chiba-ken 278-8510, Japan.

Various types of Z-scheme systems for water splitting under visible light irradiation were successfully developed by employing Rh- and Ir-doped metal oxide powdered materials with relatively narrow energy gaps (EG): BaTa2O6:Ir,La (EG: 1.9-2.0 eV), NaTaO3:Ir,La (EG: 2. Read More

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http://dx.doi.org/10.1039/c8fd00209fDOI Listing

Characterization of Intracellular Peptides from Zebrafish () Brain.

Zebrafish 2019 Apr 24. Epub 2019 Apr 24.

1 Bioscience Institute, São Paulo State University, São Vicente, Brazil.

Peptides represent a large class of cell signaling molecules, and they are mainly produced by the classical secretory pathway or during protein degradation. The peptide profile of (zebrafish) shows a lack of information when compared with other consolidated animal models. The aim of this work was to characterize the peptide profile of zebrafish brain by using triplex reductive methylation of amines labeling and liquid chromatography coupled to electron spray mass spectrometry. Read More

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https://www.liebertpub.com/doi/10.1089/zeb.2018.1718
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http://dx.doi.org/10.1089/zeb.2018.1718DOI Listing
April 2019
1 Read

Alpha-Tocopherol and contrast-induced nephropathy: a meta-analysis of randomized controlled trials.

Int J Vitam Nutr Res 2019 Apr 24:1-9. Epub 2019 Apr 24.

8 Diabetology, Azienda Ospedaliero-Universitaria Careggi and University of Florence, Florence, Italy.

Contrast-induced nephropathy (CIN) is a relevant cause of acute renal dysfunction and is associated with an increased morbidity and mortality. Purpose: Verify the effect of α-tocopherol pre-treatment on CIN prevention in subjects with chronic kidney disease. A Medline/Embase and clinicaltrials. Read More

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https://econtent.hogrefe.com/doi/10.1024/0300-9831/a000573
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http://dx.doi.org/10.1024/0300-9831/a000573DOI Listing
April 2019
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The Most Beautiful Man: An Integration of Hypnosis and Biofeedback for Depression and Dissociation.

Authors:
Donald Moss

Am J Clin Hypn 2019 Apr;61(4):322-334

a Saybrook University , Oakland , CA.

Hypnosis and biofeedback techniques are evidence-based psychophysiological therapies that can be applied with a wide variety of medical and mental health disorders. Research shows efficacy for anxiety, depression, post-traumatic stress disorder (PTDS), chronic pain, hypertension, fibromyalgia, and a host of other disorders. Hypnosis and biofeedback can also augment the effectiveness of psychotherapy. Read More

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http://dx.doi.org/10.1080/00029157.2018.1517082DOI Listing

Non-specialist palliative care: A principle-based concept analysis.

Palliat Med 2019 Apr 24:269216319840963. Epub 2019 Apr 24.

School of Nursing and Midwifery, Trinity College Dublin, The University of Dublin, Ireland.

Background: Building palliative care capacity among all healthcare practitioners caring for patients with chronic illnesses, who do not work in specialist palliative care services (non-specialist palliative care), is fundamental in providing more responsive and sustainable palliative care. Varying terminology such as 'generalist', 'basic' and 'a palliative approach' are used to describe this care but do not necessarily mean the same thing. Internationally, there are also variations between levels of palliative care which means that non-specialist palliative care may be applied inconsistently in practice because of this. Read More

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http://dx.doi.org/10.1177/0269216319840963DOI Listing

Enhanced production of recombinant Staphylococcus simulans lysostaphin using medium engineering.

Prep Biochem Biotechnol 2019 Apr 24:1-8. Epub 2019 Apr 24.

e Department of Bioengineering , Gebze Technical University , Gebze , Kocaeli , Turkey.

Staphylococcus aureus, among other staphylococcal species, developed multidrug resistance and causes serious health risks that require complex treatments. Therefore, the development of novel and effective strategies to combat these bacteria has been gaining importance. Since Staphylococcus simulans lysostaphin is a peptidoglycan hydrolase effective against staphylococcal species, the enzyme has a significant potential for biotechnological applications. Read More

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http://dx.doi.org/10.1080/10826068.2019.1599393DOI Listing

Quantification of 1D, a novel derivative of curcumin with potential antitumor activity, in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study in rats.

Pharm Biol 2019 Dec;57(1):287-294

a Department of Pharmacy , the Affiliated Hospital of Qingdao University , Qingdao , PR China.

Context: 1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines.

Objective: To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of 1 D in rat plasma.

Materials And Methods: An aliquot of 50 μL plasma sample was processed by protein precipitation with methanol. Read More

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http://dx.doi.org/10.1080/13880209.2019.1603243DOI Listing
December 2019

Genotoxicity Evaluation of the Soybean Isoflavone Genistein in Human Papillary Thyroid Cancer Cells. Study of Its Potential Use in Thyroid Cancer Therapy.

Nutr Cancer 2019 Apr 24:1-10. Epub 2019 Apr 24.

b Department of Clinical and Experimental Medicine - Section of Applied Biology and Genetics , University of Pisa , Pisa , Italy.

Genistein is one of the several known isoflavonic phytoestrogens found in a number of plants, with soybeans and soy products being the primary food source. The aim of the study is to evaluate if genistein is able to exert antineoplastic action in primary human papillary thyroid cancer (PTC) cells. Thyroid tissues were treated with genistein (1-10-50-100 µM). Read More

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http://dx.doi.org/10.1080/01635581.2019.1604004DOI Listing

Introducing Horizons.

Authors:
Terry E Graham

Appl Physiol Nutr Metab 2019 May;44(5):iii

Editor, Applied Physiology, Nutrition, and Metabolism.

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http://dx.doi.org/10.1139/apnm-2019-0078DOI Listing

The effects of quercetin supplementation on lipid profiles and inflammatory markers among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials.

Crit Rev Food Sci Nutr 2019 Apr 24:1-14. Epub 2019 Apr 24.

b Research Center for Biochemistry and Nutrition in Metabolic Diseases , Kashan University of Medical Sciences , Kashan , Iran.

Aims: This systematic review and meta-analysis of randomized controlled trials (RCTs) was performed to determine the effect of quercetin administration on lipid profiles and inflammatory markers among patients with metabolic syndrome (MetS) and related disorders.

Methods: We searched systematically online databases including Cochrane Library, EMBASE, MEDLINE, and Web of Science to identify the relevant RCTs until November 2018. Q-test and I statistics were applied to assess heterogeneity among included studies. Read More

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http://dx.doi.org/10.1080/10408398.2019.1604491DOI Listing

Dose-painted volumetric modulated arc therapy of high-grade glioma using 3,4-dihydroxy-6-[F]fluoro-l-phenylalanine positron emission tomography.

Br J Radiol 2019 Apr 24:20180901. Epub 2019 Apr 24.

3 Department of Radiation Oncology, BC Cancer - Vancouver , Vancouver , British Columbia, Canada.

Objectives: To determine whether dose painting with volumetric modulated arc therapy (VMAT) for high-grade gliomas using 3,4-dihydroxy-6-[F]fluoro- l -phenylalanine (F-FDOPA) positron emission tomography (PET) could achieve dose-escalated coverage of biological target volumes (BTVs) without increasing the dose to cranial organs at risk.

Methods: Ten patients with high-grade gliomas underwent CT, MRI, and F-FDOPA PET/CT images for postoperative radiation therapy planning. Two VMAT plans were retrospectively generated for each patient: a conventional plan with 60 Gy in 30 fractions to the planning target volume (PTV) delineated on MRI and a dose-escalated plan with a maximum dose of 80 Gy in 30 fractions to BTVs. Read More

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http://dx.doi.org/10.1259/bjr.20180901DOI Listing

Iron-Catalyzed Tandem Three-Component Alkylation: Access to α-Methylated Substituted Ketones.

Org Lett 2019 Apr 24. Epub 2019 Apr 24.

Normandie Université, LCMT, ENSICAEN, UNICAEN, CNRS, 6 boulevard du Maréchal Juin , Caen 14000 , France.

The borrowing hydrogen strategy has been applied in the synthesis of α-branched methylated ketones via a tandem three-component reaction catalyzed by a diaminocyclopentadienone iron tricarbonyl complex. Various alkyl and aromatic methyl ketones underwent dialkylation with various primary alcohols and methanol as alkylating agents in mild reaction conditions and good yields. Deuterium labeling experiments suggested that the benzylic alcohol was the hydrogen source in this tandem process. Read More

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http://dx.doi.org/10.1021/acs.orglett.9b00630DOI Listing

Development of The ReaxFF Reactive Force Field for Inherent Point Defects in the Si/Silica System.

J Phys Chem A 2019 Apr 24. Epub 2019 Apr 24.

We redeveloped the ReaxFF force field parameters for Si/O/H interactions that enable Molecular Dynamics (MD) simulations of Si/SiO 2 interfaces and O-diffusion in bulk Si at high temperatures, in particular with respect to point defect stability and migration. Our calculations show that the new force field framework (ReaxF F present ) which was guided by the extensive Quantum Mechanics (QM)-based training set de- scribes correctly the underlying mechanism of the O-migration in Si network, namely, the diffusion of O in bulk Si occurs by jumping between the neighboring bond-centered sites along a path in the (110) plane, and during the jumping, O goes through the asymmetric transition state at the split site. Additionally, the ReaxF F present predicts the diffusion barrier of O-interstitial in the bulk Si of 64. Read More

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http://dx.doi.org/10.1021/acs.jpca.9b01481DOI Listing

Basic Structure of Melanoidins Formed in the Maillard Reaction of 3-Deoxyglucosone and γ-Aminobutyric Acid.

J Agric Food Chem 2019 Apr 24. Epub 2019 Apr 24.

Institut für Lebensmitteltechnologie und Lebensmittelchemie, Fachgebiet Lebensmittelchemie und Analytik , Technische Universität Berlin , Gustav-Meyer-Allee 25 , 13355 Berlin , Germany.

Melanoidins are formed in foods during processing through the Maillard reaction between carbohydrates and amino compounds. The aim of this study was to draw conclusions about the formation mechanism and the structure of melanoidins formed at low water contents and low temperatures. In the Maillard reaction of d-glucose and γ-aminobutyric acid at low water contents 3-deoxyglucosone is the most important intermediate. Read More

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http://dx.doi.org/10.1021/acs.jafc.9b00202DOI Listing

Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress and Intestinal Permeability Using Cell Models.

J Agric Food Chem 2019 Apr 24. Epub 2019 Apr 24.

Proteins present in infant formulas are modified by oxidation and glycation during processing. Modified amino acid residues released from proteins may be absorbed in the gastrointestinal tract, and pose a health risk to infants. In this study markers of glycation, furosine (1. Read More

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http://dx.doi.org/10.1021/acs.jafc.9b01324DOI Listing
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