Appl Math Lett 2010 Dec;23(12):1412-1415
Center for Research in Scientific Computation, Center for Quantitative Sciences in Biomedicine, North Carolina State University, Raleigh, NC 27695-8213 and INRIA Rocquencourt, Projet BANG, Domaine de Voluceau, 78153 Rocquencourt, France.
We present a general class of cell population models that can be used to track the proliferation of cells which have been labeled with a fluorescent dye. The mathematical models employ fluorescence intensity as a structure variable to describe the evolution in time of the population density of proliferating cells. While cell division is a major component of changes in cellular fluorescence intensity, models developed here also address overall label degradation. Read More