Appl Magn Reson 2018 Jan 4;49(1):3-24. Epub 2017 Dec 4.
Department of Radiology, Washington University, Saint Louis, MO, United States.
Recently, a number of MRI protocols have been reported that seek to exploit the effect of dissolved oxygen (O, paramagnetic) on the longitudinal H relaxation of tissue water, thus providing image contrast related to tissue oxygen content. However, tissue water relaxation is dependent on a number of mechanisms, and this raises the issue of how best to model the relaxation data. This problem, the model selection problem, occurs in many branches of science and is optimally addressed by Bayesian probability theory. Read More