110 results match your criteria Applied Magnetic Resonance[Journal]


250 MHz Rapid Scan Cross Loop Resonator.

Appl Magn Reson 2019 Mar 3;50(1-3):333-345. Epub 2018 Oct 3.

Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80210.

A 25 mm diameter 250 MHz crossed-loop resonator was designed for rapid scan electron paramagnetic resonance imaging. It has a saddle coil for the driven resonator and a fine wire, loop gap resonator for the sample resonator. There is good separation of E and B fields and high isolation between the two resonators, permitting a wide range of sample types to be measured. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-018-1078-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380496PMC
March 2019
1 Read

Nucleotide Spin Labeling for ESR Spectroscopy of ATP-Binding Proteins.

Appl Magn Reson 2018 Dec 14;49(12):1385-1395. Epub 2018 Nov 14.

Department of Chemistry and Chemical Biology, Cornell University Ithaca, NY.

Site-directed spin labeling of proteins by chemical modification of engineered cysteine residues with the molecule MTSSL (1-Oxyl-2,2,5,5-tetramethylpyrroline-3-methyl methanethiosulfonate) has been an invaluable tool for conducting double electron electron resonance (DEER) spectroscopy experiments. However, this method is generally limited to recombinant proteins with a limited number of reactive Cys residues that when modified will not impair protein function. Here we present a method that allows for spin-labeling of protein nucleotide binding sites by adenosine diphosphate (ADP) modified with a nitroxide moiety on the β-phosphate (ADP-β-S-SL). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-018-1070-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342010PMC
December 2018

One-Dimensional NMR Imaging of High-Temperature First-Drying in Monolithics.

Appl Magn Reson 2018 18;49(7):739-753. Epub 2018 May 18.

2Eindhoven University of Technology, De Rondom 70, 5612 AP Eindhoven, The Netherlands.

In this study a specialized high-temperature nuclear magnetic resonance (NMR) setup is presented for measuring free moisture in monolithic refractory castables during one-sided heating (100-300 °C). This setup makes use of a high thermal-stability Birdcage-coil for measuring the quantitative moisture content at high-temperatures, while also utilizing a mini-coil for calibrating transverse relaxation changes, as a function of temperature and hydration state, taking place in the sample throughout a drying experiment. We employ a high-temperature correction scheme that calibrates the effects of rising temperatures on the NMR signal. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-018-1018-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021476PMC

Autobiography of James S. Hyde.

Authors:
James S Hyde

Appl Magn Reson 2017 Dec 27;48(11-12):1103-1147. Epub 2017 Oct 27.

Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plan Road, Milwaukee, WI 53226; 414-955-4000; ORCID: 0000-0002-3023-1243.

The papers, book chapters, reviews, and patents by James S. Hyde in the bibliography of this document have been separated into EPR and MRI sections, and within each section by topics. Within each topic, publications are listed chronologically. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0950-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022859PMC
December 2017

Kinetic studies of complex biomedical process by magnetic resonance: Cuban experiences.

Appl Magn Reson 2018 26;49(6):589-598. Epub 2018 Mar 26.

2Center for Genetic Engineering and Biotechnology, Havana, Cuba.

The potentials of the magnetic resonance (MR) methods in the research of biomedical systems have been demonstrated during the 70 years of its existence. It is presented that the Cuban experience in quantitative magnetic resonance associated with molecular, preclinical and clinical studies of significant diseases and drugs development. MR "in vitro" and "in vivo" studies of sickle cell disease, the diabetic foot ulcer, the brain tumor response and the magnetic nano-particle pharmacokinetics, are presented as example. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00723-018-0985-2
Publisher Site
http://dx.doi.org/10.1007/s00723-018-0985-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988773PMC
March 2018
4 Reads

N-C Dipole Couplings in Smectic Mesophase of a Thermotropic Ionic Liquid.

Appl Magn Reson 2018 19;49(6):553-562. Epub 2018 Apr 19.

3Laboratory of Biomolecular NMR, St. Petersburg State University, St. Petersburg, 199034 Russia.

Unique combination of ionic conductivity and anisotropic physical properties in ionic liquid crystals leads to new dynamic properties exploited in modern technological applications. Structural and dynamics information at atomic level for molecules and ions in mesophases can be obtained by nuclear magnetic resonance (NMR) spectroscopy through the measurements of dipole-dipole spin couplings. While C-H and N-H dipolar NMR spectra can be routinely acquired in samples with natural isotopic abundance, recording N-C dipolar NMR spectra is challenging because of the unfavourable combination of two rare isotopes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-018-1000-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988779PMC
April 2018
1 Read

Saturation recovery EPR spin-labeling method for quantification of lipids in biological membrane domains.

Appl Magn Reson 2017 Dec 22;48(11-12):1355-1373. Epub 2017 Jul 22.

Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI USA.

The presence of integral membrane proteins induces the formation of distinct domains in the lipid bilayer portion of biological membranes. Qualitative application of both continuous wave (CW) and saturation recovery (SR) electron paramagnetic resonance (EPR) spin-labeling methods allowed discrimination of the bulk, boundary, and trapped lipid domains. A recently developed method, which is based on the CW EPR spectra of phospholipid (PL) and cholesterol (Chol) analog spin labels, allows evaluation of the relative amount of PLs (% of total PLs) in the boundary plus trapped lipid domain and the relative amount of Chol (% of total Chol) in the trapped lipid domain []. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967259PMC
December 2017
2 Reads

Spin Dynamics of (Sc[Formula: see text]Lu[Formula: see text])[Formula: see text]In Studied by Electron Spin Resonance.

Appl Magn Reson 2018 13;49(5):493-498. Epub 2018 Feb 13.

1Max Planck Institute for Chemical Physics of Solids, Dresden, Germany.

The electron spin resonance (ESR) of conduction electrons is reported for the weak itinerant ferromagnet Sc[Formula: see text]In which, upon chemical substitution with Lu, shows a suppression of ferromagnetic correlations. A well-defined ESR lineshape of Dysonian type characterizes the spectra. The ESR linewidth, determined by the spin dynamics, displays a broad minimum only for the Sc[Formula: see text]In compound. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-018-0987-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915522PMC
February 2018

Bayesian Modeling of NMR Data: Quantifying Longitudinal Relaxation , and with a Tissue-Water-Relaxation Mimic (Crosslinked Bovine Serum Albumin).

Appl Magn Reson 2018 Jan 4;49(1):3-24. Epub 2017 Dec 4.

Department of Radiology, Washington University, Saint Louis, MO, United States.

Recently, a number of MRI protocols have been reported that seek to exploit the effect of dissolved oxygen (O, paramagnetic) on the longitudinal H relaxation of tissue water, thus providing image contrast related to tissue oxygen content. However, tissue water relaxation is dependent on a number of mechanisms, and this raises the issue of how best to model the relaxation data. This problem, the model selection problem, occurs in many branches of science and is optimally addressed by Bayesian probability theory. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918291PMC
January 2018
6 Reads

Versus -Azobenzene: Precise Determination of NMR Parameters and Analysis of Long-Lived States of N Spin Pairs.

Appl Magn Reson 2018 22;49(3):293-307. Epub 2017 Dec 22.

1International Tomography Center SB RAS, Novosibirsk, 630090 Russia.

We provide a detailed evaluation of nuclear magnetic resonance (NMR) parameters of the - and -isomers of azobenzene (AB). For determining the NMR parameters, such as proton-proton and proton-nitrogen -couplings and chemical shifts, we compared NMR spectra of three different isotopomers of AB: the doubly N labeled azobenzene, N,N'-AB, and two partially deuterated AB isotopomers with a single N atom. For the total lineshape analysis of NMR spectra, we used the recently developed ANATOLIA software package. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0968-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811614PMC
December 2017
5 Reads

Towards Determination of Distances Between Nanoparticles and Grafted Paramagnetic Ions by NMR Relaxation.

Appl Magn Reson 2018 5;49(2):195-208. Epub 2017 Oct 5.

2Department of Mathematics and Physics, Institute of Physics, University of Szczecin, 70-451 Szczecin, Poland.

We developed an approach for determining distances between carbon nanoparticles and grafted paramagnetic ions and molecules by means of nuclear spin-lattice relaxation data. The approach was applied to copper-, cobalt- and gadolinium-grafted nanodiamonds, iron-grafted graphenes, manganese-grafted graphene oxide and activated carbon fibers that adsorb paramagnetic oxygen molecules. Our findings show that the aforementioned distances vary in the range of 2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0952-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775391PMC
October 2017

Determination of Carbon Chain Lengths of Fatty Acid Mixtures by Time Domain NMR.

Appl Magn Reson 2018 30;49(2):185-193. Epub 2017 Sep 30.

Fiber Laboratory, South-Eastern Finland University of Applied Sciences, Vipusenkatu 10, 57200 Savonlinna, Finland.

Average carbon chain length is a key parameter that defines the quality of liquid biofuels. In this paper, a method for the determination of carbon chain lengths of fatty acid mixtures is presented. The approach is based on proton relaxation rates measured by time domain nuclear magnetic resonance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0953-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775386PMC
September 2017

Resonators for In Vivo Imaging: Practical Experience.

Appl Magn Reson 2017 Dec 22;48(11-12):1227-1247. Epub 2017 Sep 22.

Center for EPR Imaging In Vivo Physiology, Department of Radiation and Cellular Oncology, University of Chicago, IL, USA.

Resonators for preclinical electron paramagnetic resonance imaging have been designed primarily for rodents and rabbits and have internal diameters between 16 and 51 mm. Lumped circuit resonators include loop-gap, Alderman-Grant, and saddle coil topologies and surface coils. Bimodal resonators are useful for isolating the detected signal from incident power and reducing dead time in pulse experiments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0947-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788320PMC
December 2017
2 Reads

Spin-label Order Parameter Calibrations for Slow Motion.

Authors:
Derek Marsh

Appl Magn Reson 2018 9;49(1):97-106. Epub 2017 Sep 9.

1Max-Planck-Institut für biophysikalische Chemie, 37070 Göttingen, Germany.

Calibrations are given to extract orientation order parameters from pseudo-powder electron paramagnetic resonance line shapes of N-nitroxide spin labels undergoing slow rotational diffusion. The nitroxide -axis is assumed parallel to the long molecular axis. Stochastic-Liouville simulations of slow-motion 9. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0940-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752820PMC
September 2017

High-pressure EPR spectroscopy studies of the lipopolysaccharide transport proteins LptA and LptC.

Appl Magn Reson 2017 Dec 21;48(11-12):1341-1353. Epub 2017 Sep 21.

National Biomedical EPR Center, Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 USA.

The use of pressure is an advantageous approach to the study of protein structure and dynamics because it can shift the equilibrium populations of protein conformations toward higher energy states that are not of sufficient population to be observable at atmospheric pressure. Recently, the Hubbell group at the University of California, Los Angeles, reintroduced the application of high pressure to the study of proteins by electron paramagnetic resonance (EPR) spectroscopy. This methodology is possible using X-band EPR spectroscopy due to advances in pressure intensifiers, sample cells, and resonators. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0948-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761346PMC
December 2017

EPR UNIFORM FIELD SIGNAL ENHANCEMENT BY DIELECTRIC TUBES IN CAVITIES.

Appl Magn Reson 2017 Dec 18;48(11-12):1185-1204. Epub 2017 Sep 18.

Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plan Road, Milwaukee, WI 53226.

The dielectric tube resonator (DTR) for EPR spectroscopy is introduced. It is defined as a metallic cylindrical TE microwave cavity that contains a dielectric tube centered on the axis of the cylinder. Contour plots of dimensions of the metallic cylinder to achieve resonance at 9. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0935-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761080PMC
December 2017
1 Read

An X-Band Crossed-Loop EPR Resonator.

Appl Magn Reson 2017 Dec 14;48(11-12):1219-1226. Epub 2017 Sep 14.

Department of Chemistry and Biochemistry and Center for EPR Imaging In Vivo Physiology, University of Denver, Denver, CO 80208.

A copper X-band (9.22 GHz) cross loop resonator has been constructed for use with 4 mm sample tubes. The Q for the two resonators are 380 and 350, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0945-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739319PMC
December 2017
7 Reads

A Pulse EPR 25 mT magnetometer with 10ppm resolution.

Appl Magn Reson 2017 Aug 5;48(8):805-811. Epub 2017 Jun 5.

Center for EPR Imaging In Vivo Physiology, Department of Radiation and Cellular Oncology, University of Chicago, IL, USA.

A magnetometer designed for permanent magnet manufacturing and operated around 25 mT with 10ppm absolute accuracy is described. The magnetometer uses pulse electron paramagnetic resonance (EPR) methodology. The use of a pulsed broadband acquisition allowed reliable measurements in the presence of the magnetic field gradient and in relatively inhomogeneous magnetic fields of un-shimmed magnets. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0902-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685537PMC
August 2017
1 Read

Uniform Field Re-entrant Cylindrical TE[Formula: see text] Cavity for Pulse Electron Paramagnetic Resonance Spectroscopy at Q-band.

Appl Magn Reson 2017 30;48(11):1301-1314. Epub 2017 Sep 30.

Max Planck Institut für Chemische Energiekonversion, Stiftstrasse 34-36, 45470 Mülehim an der Ruhr, Germany.

Uniform field (UF) resonators create a region-of-interest, where the sample volume receives a homogeneous microwave magnetic field ([Formula: see text]) excitation. However, as the region-of-interest is increased, resonator efficiency is reduced. In this work, a new class of uniform field resonators is introduced: the uniform field re-entrant cylindrical TE[Formula: see text] cavity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0955-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668368PMC
September 2017
4 Reads

Jim Hyde and the ENDOR Connection: A Personal Account.

Appl Magn Reson 2017 23;48(11):1149-1183. Epub 2017 Oct 23.

Max-Planck-Institute for Chemical Energy Conversion, 45470 Mülheim an der Ruhr, Germany.

In this minireview, we report on our year-long EPR work, such as electron-nuclear double resonance (ENDOR), pulse electron double resonance (PELDOR) and ELDOR-detected NMR (EDNMR) at X-band and W-band microwave frequencies and magnetic fields. This report is dedicated to James S. Hyde and honors his pioneering contributions to the measurement of spin interactions in large (bio)molecules. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-017-0959-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668355PMC
October 2017
3 Reads

EPR Line Shifts and Line Shape Changes Due to Spin Exchange Between Nitroxide Free Radicals in Liquids 10. Spin-Exchange Frequencies of the Order of the Nitrogen Hyperfine Interaction: A Hypothesis.

Appl Magn Reson 2017 Feb 3;48(2):175-200. Epub 2016 Dec 3.

Department of Physics and Astronomy, The Center for Biological Physics, California State University at Northridge, Northridge, CA 91330, USA.

The behavior of Electron paramagnetic resonance spectra due to N and N nitroxide free radicals undergoing spin exchange in liquids at high frequencies , of the same order of magnitude as the nitrogen hyperfine coupling constant is investigated. The well known features are reconfirmed: (1) at low values of where the lines broaden, shift toward the center of the spectrum, and change shape due to the introduction of a resonance of the form of a dispersion component; (2) at values of comparable to , the line merge into one; and (3) at values much larger than , the merged line narrows. It is found that each line of a spectrum may be decomposed into an admixture of a single absorption and a single dispersion component of Lorentzian shape. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0854-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590052PMC
February 2017
3 Reads

Na and Al NMR Study of Structure and Dynamics in Mordenite.

Appl Magn Reson 2017 9;48(2):115-124. Epub 2016 Nov 9.

Department of Physics, Ben-Gurion University of the Negev, P. O. Box 653, 8410501 Be'er Sheva, Israel.

Temperature dependencies of Al and Na nuclear magnetic resonance spectra and spin-lattice relaxations in mordenite have been studied in static and magic angle spinning regimes. Our data show that the spin-lattice relaxations of the Na and Al nuclei are mainly governed by interaction of nuclear quadrupole moments with electric field gradients of the crystal, modulated by translational motion of water molecules in the mordenite channels. At temperatures below 200 K, the dipolar interaction of nuclear spins with paramagnetic impurities becomes an important relaxation mechanism of the Na and Al nuclei. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0847-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258800PMC
November 2016

NMR Techniques in Metabolomic Studies: A Quick Overview on Examples of Utilization.

Appl Magn Reson 2017 2;48(1):1-21. Epub 2016 Nov 2.

Department of Organic Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, Grunwaldzka 6 Str., 60-780 Poznan, Poland ; Foundation for Development of Science and Business on Medical and Exact Sciences Area, Legnicka 65 Str., 54-206 Wrocław, Poland.

Metabolomics is a rapidly developing branch of science that concentrates on identifying biologically active molecules with potential biomarker properties. To define the best biomarkers for diseases, metabolomics uses both models (in vitro, animals) and human, as well as, various techniques such as mass spectroscopy, gas chromatography, liquid chromatography, infrared and UV-VIS spectroscopy and nuclear magnetic resonance. The last one takes advantage of the magnetic properties of certain nuclei, such as H, C, P, F, especially their ability to absorb and emit energy, what is crucial for analyzing samples. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0846-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222922PMC
November 2016
6 Reads

Temperature-Dependent Oxygen Effect on NMR -[Formula: see text] Relaxation-Diffusion Correlation of -Alkanes.

Appl Magn Reson 2016 19;47(12):1391-1408. Epub 2016 Sep 19.

School of Petroleum Engineering, The University of New South Wales, Sydney, NSW 2052 Australia.

Nuclear magnetic resonance (NMR) diffusion-relaxation correlation experiments (-[Formula: see text]) are widely used for the petrophysical characterisation of rocks saturated with petroleum fluids both in situ and for laboratory analyses. The encoding for both diffusion and relaxation offers increased fluid typing contrast by discriminating fluids based on their self-diffusion coefficients, while relaxation times provide information about the interaction of solid and fluid phases and associated confinement geometry (if NMR responses of pure fluids at particular temperature and pressure are known). Petrophysical interpretation of -[Formula: see text] correlation maps is typically assisted by the "standard alkane line"-a relaxation-diffusion correlation valid for pure normal alkanes and their mixtures in the absence of restrictions to diffusing molecules and effects of internal gradients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0830-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099375PMC
September 2016

Parameter Estimation Error Dependency on the Acquisition Protocol in Diffusion Kurtosis Imaging.

Appl Magn Reson 2016 17;47(11):1229-1238. Epub 2016 Sep 17.

Norwich Medical School, University of East Anglia, Bob Champion Research and Educational Building, Room 2.18, James Watson Road, Norwich Research Park, Norwich, NR4 7UQ UK.

Mono-exponential kurtosis model is routinely fitted on diffusion weighted, magnetic resonance imaging data to describe non-Gaussian diffusion. Here, the purpose was to optimize acquisitions for this model to minimize the errors in estimating diffusion coefficient and kurtosis. Similar to a previous study, covariance matrix calculations were used, and coefficients of variation in estimating each parameter of this model were calculated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0829-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073116PMC
September 2016
2 Reads

Proton Dipolar Spin-Lattice Relaxation in Nano-channels of Natrolite.

Appl Magn Reson 2016;47:895-902. Epub 2016 Jun 25.

V.I.Vernadsky Crimean Federal University, 295007 Simferopol, Crimea.

The H nuclear magnetic resonance (NMR) spectra and the dipolar spin-lattice relaxation time for H in the natural natrolite (NaAlSiO·2HO) have been measured in the temperature range of 190-390 K. From the temperature transformations of H NMR spectra, it follows that at  > 300 K, the diffusion of water molecules along the nano-channels is observed. From experimental data, it follows that the 180° flip motion of the water molecules takes place in natrolite. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0805-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956723PMC

Rapid Freeze-Quench EPR Spectroscopy: Improved Collection of Frozen Particles.

Appl Magn Reson 2016;47:643-653. Epub 2016 Apr 30.

Huygens-Kamerlingh Onnes Laboratory, Department of Physics, Leiden University, P.O. Box 9504, 2300 RA Leiden, The Netherlands.

Rapid freeze-quench (RFQ) in combination with electron paramagnetic resonance (EPR) spectroscopy at X-band is a proven technique to trap and characterize paramagnetic intermediates of biochemical reactions. Preparation of suitable samples is still cumbersome, despite many attempts to remedy this problem, and limits the wide applicability of RFQ EPR. We present a method, which improves the collection of freeze-quench particles from isopentane and their packing in an EPR tube. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0783-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875044PMC
April 2016
1 Read

The Lipari-Szabo Model-Free Analysis as a Method for Study of Molecular Motion in Solid State Heteronuclear Systems Using NMR Off-Resonance.

Appl Magn Reson 2016;47:567-574. Epub 2016 Apr 28.

High Pressure Physics Division, Faculty of Physics, Adam Mickiewicz University, Umultowska 85, 61-614 Poznan, Poland.

In the present work, a new method for measuring motional parameters using the off-resonance technique was described. The Lipari-Szabo model-free formalism was used to analyze molecular dynamics in a heteronuclear system [1, 2]. Cross-relaxation solid state nuclear magnetic resonance off-resonance experiments were performed on a homebuilt pulse spectrometer operating at the frequency of 30. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0785-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875056PMC

Eight-Channel Monopole Array Using ICE Decoupling for Human Head MR Imaging at 7 T.

Appl Magn Reson 2016 05 7;47(5):527-538. Epub 2016 Apr 7.

Department of Radiology and Biomedical Imaging, University of California San Francisco, Byers Hall, Room 102, 1700 4th ST, San Francisco, CA 941582330, USA.

Due to the unique structure of radiative coil elements, traditional decoupling methods face technical challenges in reducing the electromagnetic coupling of the radiative arrays. In this study, we aim to investigate the possibility of using the recently introduced induced current elimination (ICE) decoupling technique for cylindrical shaped radiative coil array designs. To evaluate the method, an eight-channel transmit/receive monopole array with the ICE decoupling, suitable for human head imaging at 7 T, was built and comparatively investigated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0775-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638452PMC
May 2016
8 Reads

Simulation verification of SNR and parallel imaging improvements by ICE-decoupled loop array in MRI.

Appl Magn Reson 2016 Apr 29;47(4):395-403. Epub 2016 Feb 29.

;

Transmit/receive L/C loop arrays with the induced current elimination (ICE) or magnetic wall decoupling method has shown high signal-to-noise (SNR) and excellent parallel imaging ability for MR imaging at ultrahigh fields, e.g., 7 T. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-016-0764-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808813PMC
April 2016
10 Reads

H, Na and Cl Imaging in Cementitious Materials with NMR.

Appl Magn Reson 2016;47:265-276. Epub 2016 Feb 1.

Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.

A set-up especially designed for semi-simultaneous measurements of H, Na and Cl in ordinary cementitious materials using nuclear magnetic resonance was built. This setup makes use of the main field of a whole body magnetic resonance imaging system (Philips Intera), which has allowed us to combine two measurement setups into one, i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-015-0752-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761373PMC
February 2016

Sample Shuttling Relaxometry of Contrast Agents: NMRD Profiles above 1 T with a Single Device.

Appl Magn Reson 2016;47:237-246. Epub 2016 Jan 30.

Département de Chimie, École Normale Supérieure - PSL Research University, 24 rue Lhomond, 75005 Paris, France ; Sorbonne Universités UPMC Univ Paris 06, LBM, 4 place Jussieu, 75005 Paris, France ; UMR 7203 LBM, CNRS, 75005 Paris, France.

Nuclear magnetic relaxation dispersion (NMRD) profiles are essential tools to evaluate the efficiency and investigate the properties of magnetic compounds used as contrast agents for magnetic resonance imaging (MRI), namely gadolinium chelates and superparamagnetic iron oxide particles. These curves represent the evolution of proton relaxation rates with the magnetic field. NMRD profiles are unparalleled to probe extensively the spectral density function involved in the relaxation of water in the presence of the paramagnetic ion or the magnetic nanoparticles. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-015-0751-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761365PMC
January 2016
9 Reads

Closely-spaced double-row microstrip RF arrays for parallel MR imaging at ultrahigh fields.

Appl Magn Reson 2015 Nov 30;46(11):1239-1248. Epub 2015 Jun 30.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California 94158, USA ; UCSF/UC Berkeley Joint Graduate Group in Bioengineering, San Francisco, California 94158, USA.

Radiofrequency (RF) coil arrays with high count of elements, e.g., closely-spaced multi-row arrays, exhibit superior parallel imaging performance in MRI. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00723-015-0712-1
Publisher Site
http://dx.doi.org/10.1007/s00723-015-0712-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617305PMC
November 2015
8 Reads

Spin-labeled small unilamellar vesicles with the -sensitive saturation-recovery EPR display as an oxygen sensitive analyte for measurement of cellular respiration.

Appl Magn Reson 2015 Aug 22;46(8):885-895. Epub 2015 Apr 22.

Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

This study validated the use of small unilamellar vesicles (SUVs) made of 1-palmitoyl-2-oleoylphosphatidylcholine with 1 mol% spin label of 1-palmitoyl-2-(16-doxylstearoyl)phosphatidylcholine (16-PC) as an oxygen sensitive analyte to study cellular respiration. In the analyte the hydrocarbon environment surrounds the nitroxide moiety of 16-PC. This ensures high oxygen concentration and oxygen diffusion at the location of the nitroxide as well as isolation of the nitroxide moiety from cellular reductants and paramagnetic ions that might interfere with spin-label oximetry measurements. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00723-015-0684-1
Publisher Site
http://dx.doi.org/10.1007/s00723-015-0684-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591545PMC
August 2015
1 Read

EPR Properties of Concentrated NdVO Single Crystal System.

Appl Magn Reson 2015;46(9):1023-1033. Epub 2015 Mar 18.

Institute of Physics, Faculty of Mechanical Engineering and Mechatronics, West Pomeranian University of Technology in Szczecin, Al. Piastow 17, 70-310 Szczecin, Poland.

Single crystals of NdVO were grown by the Czochralski method under ambient pressure in a nitrogen atmosphere. Obtained crystals were transparent with strong violet coloring. Temperature and angular dependences of electron paramagnetic resonance (EPR) spectra of the samples in the 3-103 K temperature range were analyzed applying Dyson like lineshape typically used for concentrated magnetic system. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-015-0659-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552780PMC

ESR and X-ray Structure Investigations on the Binding and Mechanism of Inhibition of the Native State of Myeloperoxidase with Low Molecular Weight Fragments.

Appl Magn Reson 2015;46(8):853-873. Epub 2015 May 19.

Division of Endocrine and Cardiovascular Research, Lilly Corporate Center, Eli Lilly and Company, 893 S Delaware Street, Indianapolis, IN 46285 USA.

As an early visitor to the injured loci, neutrophil-derived human Myeloperoxidase (hMPO) offers an attractive protein target to modulate the inflammation of the host tissue through suitable inhibitors. We describe a novel methodology of using low temperature ESR spectroscopy (6 K) and ™ technology to screen a diverse series of small molecules that inhibit the peroxidase function through reversible binding to the native state of MPO. Our initial efforts to profile molecules on the inhibition of MPO-initiated nitration of the Apo-A1 peptide (AEYHAKATEHL) assay showed several potent (with sub-micro molar IC50s) but spurious inhibitors that either do not bind to the heme pocket in the enzyme or retain high (>50 %) anti oxidant potential. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-015-0698-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515242PMC
May 2015
12 Reads

Hybrid monopole/loop coil array for human head MR imaging at 7T.

Appl Magn Reson 2015 May;46(5):541-550

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California 94158, USA ; UCSF/UC Berkeley Joint Graduate Group in Bioengineering, San Francisco, California 94158, USA.

The monopole coil and loop coil have orthogonal radiofrequency (RF) fields and thus are intrinsically decoupled electromagnetically if they are laid out appropriately. In this study, we proposed a hybrid monopole/loop technique which could combine the advantages of both loop arrays and monopole arrays. To investigate this technique, a hybrid RF coil array containing 4 monopole channels and 4 loop channels was developed for human head MR imaging at 7T. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-015-0656-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479412PMC
May 2015
17 Reads

Development of a Single-Sided Nuclear Magnetic Resonance Scanner for the In Vivo Quantification of Live Cattle Marbling.

Appl Magn Reson 2015;46(5):593-606. Epub 2015 Mar 18.

National Institute of Advanced Industrial Science and Technology (AIST), Central 7, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8567 Japan.

Non-invasive in vivo marbling quantification helps owners to choose the optimum nutritional management for growing cattle and buyers to more precisely evaluate grown cattle at auctions. When using time-domain proton nuclear magnetic resonance (NMR) relaxometry, it is possible to quantify muscle and fat separately by taking advantage of the difference in the spin-spin relaxation time (2) between water molecules in muscles and fat molecules, which would contribute to the non-invasive and objective determination of marbling scores. With this in mind, we developed a prototype NMR scanner (4. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-015-0657-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409640PMC
March 2015
3 Reads

Exploiting the Symmetry of the Resonator Mode to Enhance PELDOR Sensitivity.

Appl Magn Reson 2015;46(4):359-368. Epub 2014 Dec 6.

London Centre for Nanotechnology, University College London, 17-19 Gordon Street, London, WC1H 0AH UK ; Institute of Structural and Molecular Biology, University College London, Gower Street, London, WC1E 6BT UK.

Pulsed electron paramagnetic resonance (EPR) spectroscopy using microwaves at two frequencies can be employed to measure distances between pairs of paramagnets separated by up to 10 nm. The method, combined with site-directed mutagenesis, has become increasingly popular in structural biology for both its selectivity and capability of providing information not accessible through more standard methods such as nuclear magnetic resonance and X-ray crystallography. Despite these advantages, EPR distance measurements suffer from poor sensitivity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-014-0621-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359710PMC
December 2014

Gadolinium-Loaded Viral Capsids as Magnetic Resonance Imaging Contrast Agents.

Appl Magn Reson 2015 Mar 11;46(3):349-355. Epub 2015 Jan 11.

Department of Chemistry, Indiana University, Bloomington, IN 47405, USA.

Polymeric nanohybrid P22 virus capsids were used as templates for high density Gd loading to explore magnetic field-dependent (0.5-7.0 T) proton relaxivity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-014-0639-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645056PMC
March 2015
2 Reads

Rock Reservoir Properties from the Comprehensive Interpretation of Nuclear Magnetic Resonance and Mercury Injection Porosimetry Laboratory Results.

Appl Magn Reson 2015;46:95-115. Epub 2014 Nov 28.

Faculty of Geology, Geophysics and Environment Protection, AGH University of Science and Technology, al. Mickiewicza 30, 30-059 Krakow, Poland.

Combination of laboratory measurements res ults of various properties, i.e. porosity, density, permeability and mineral composition, was done to get additional factors useful in fluid flow description in the Miocene sandy-shaly formation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-014-0617-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291516PMC
November 2014
1 Read

Design and Test of Magnetic Wall Decoupling for Dipole Transmit/Receive Array for MR Imaging at the Ultrahigh Field of 7T.

Appl Magn Reson 2015 Jan 27;46(1):59-66. Epub 2014 Nov 27.

State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Bldg. 11, 15 Datun Road, Chaoyang District, Beijing 100101, China.

Radio-frequency coil arrays using dipole antenna technique have been recently applied for ultrahigh field magnetic resonance (MR) imaging to obtain the better signal-noise-ratio (SNR) gain at the deep area of human tissues. However, the unique structure of dipole antennas makes it challenging to achieve sufficient electromagnetic decoupling among the dipole antenna elements. Currently, there is no decoupling methods proposed for dipole antenna arrays in MR imaging. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-014-0612-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612434PMC
January 2015
15 Reads

Spin-label W-band EPR with seven-loop-six-gap resonator: Application to lens membranes derived from eyes of a single donor.

Appl Magn Reson 2014 Dec;45(12):1343-1358

Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

Spin-label W-band (94 GHz) EPR with a five-loop-four-gap resonator (LGR) was successfully applied to study membrane properties (L. Mainali, J.S. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00723-014-0578-7
Publisher Site
http://dx.doi.org/10.1007/s00723-014-0578-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273494PMC
December 2014
2 Reads

Proton-Electron Double-Resonance Imaging of pH using phosphonated trityl probe.

Appl Magn Reson 2014 Sep;45(9):817-826

Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Internal Medicine and Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA.

Variable Radio Frequency Proton-Electron Double-Resonance Imaging (VRF PEDRI) enables extracting a functional map from a limited number of images acquired at pre-selected EPR frequencies using specifically designed paramagnetic probes with high quality spatial resolution and short acquisition times. In this work we explored potential of VRF PEDRI for pH mapping of aqueous samples using recently synthesized pH-sensitive phosphonated trityl radical, pTR. The ratio of Overhauser enhancements measured at each pixel at two different excitation frequencies corresponding to the resonances of protonated and deprotonated forms of pTR probe allows for a pH map extraction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-014-0570-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268155PMC
September 2014
4 Reads

Computationally Efficient Steady-State Solution of the Bloch Equations for Rapid Sinusoidal Scans Based on Fourier Expansion in Harmonics of the Scan Frequency.

Appl Magn Reson 2013 Dec;44(12):1373-1379

Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80208.

Rapid-scan EPR has been shown to improve the signal-to-noise ratio relative to conventional continuous wave spectroscopy. Equations are derived for the steady-state solution to the Bloch equations as a Fourier expansion in the harmonics of the scan frequency. This simulation method is about two orders of magnitude faster than time-domain numerical integration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-013-0494-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963382PMC
December 2013
4 Reads

Application of EPR Spectroscopy to Examination of Free Radical Formation in Thermally Sterilized Flumetasone.

Appl Magn Reson 2013 29;44:1431-1443. Epub 2013 Oct 29.

Department of Biophysics, School of Pharmacy and Laboratory Medicine, Medical University of Silesia in Katowice, Jedności 8, 41-200 Sosnowiec, Poland ; Artificial Heart Laboratory, The Zbigniew Religa Foundation of Cardiac Surgery Development, Wolności 345a, 41-800 Zabrze, Poland.

Thermal formation of free radicals in flumetasone sterilized according to the pharmaceutical norms at 160, 170 and 180 °C was examined by electron paramagnetic resonance (EPR) spectroscopy. The microbiological analysis was done. Similar free radical concentrations were measured for flumetasone sterilized at 160 and 170 °C. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-013-0490-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835947PMC
October 2013
1 Read

Phase Correction-Adaptive Line Enhancement for Noise Reduction of Low-Field NMR.

Appl Magn Reson 2013 2;44:1381-1391. Epub 2013 Nov 2.

Key Laboratory of Shale Gas Exploration, Ministry of Land and Resources, Chongqing Institute of Geology and Mineral Resources, 177-9 Yangtze River 2 Road, Yuzhong, Chongqing, 400042 China ; Chongqing Shale Gas Research Centre of State Key Laboratory of Petroleum Resource and Prospecting, Chongqing, 400042 China.

The amplitude of low-field nuclear magnetic resonance (NMR) is weak, and the echo is buried in the noise. The reduction of noise is critical to accurately extract echo amplitude. Phase correction-adaptive line enhancement (PC-ALE) is proposed to noise suppression based on the principle of ALE and NMR spin-echo characteristics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-013-0486-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835948PMC
November 2013
4 Reads

Frequency-Selective Fat Suppression Radiofrequency Pulse Train to Remove Olefinic Fats.

Authors:
Takayuki Abe

Appl Magn Reson 2013 19;44:1213-1221. Epub 2013 Jul 19.

Molecular Imaging Center, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555 Japan.

CHESS pulse can suppress the signal originating from aliphatic fat protons but cannot suppress the signal from olefinic fat protons, which is near the resonance frequency of water protons. Adipose tissue contains various fat species; aliphatic fat comprises about 90 % and olefinic fat about 10 % of adipose tissue. Thus, CHESS pulse cannot be used to suppress the signal from adipose tissue completely. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-013-0474-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751390PMC
July 2013
1.170 Impact Factor

Electron Spin Resonance (ESR) Dating of Calcareous Fault Gouge of the Ushikubi Fault, Central Japan.

Appl Magn Reson 2013 10;44:1105-1123. Epub 2013 Jul 10.

Graduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama, 930-8555 Japan.

The ages of fault events of active faults have been estimated using electron spin resonance (ESR) signals of siliceous gouges. This technique of ESR method is limited by obtaining only ages that are greater than tens of millennia. So this study focuses on developing a new technique of using calcareous gouges to gain an insight into the ages of latest seismogenic event within the Holocene. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-013-0471-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731512PMC

A Solid-State NMR Investigation of MQ Silicone Copolymers.

Appl Magn Reson 2013 31;44:1015-1025. Epub 2013 May 31.

Institute of Problems of Chemical Physics, Academician Semenov Avenue 1, Chernogolovka, 142432 Russian Federation.

The structure of MQ copolymers of the general chemical formula [(CH)SiO] [SiO] was characterized by means of solid-state magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy. The MQ copolymers are highly branched polycyclic compounds (densely cross-linked nanosized networks). MQ copolymers were prepared by hydrolytic polycondensation in active medium. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00723-013-0456-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731513PMC
May 2013
4 Reads