Oleoylethanolamide increases the expression of PPAR-Α and reduces appetite and body weight in obese people: A clinical trial.
- Payahoo Laleh,
- Khaje-Bishak Yaser,
- Barzegari Abolfazl,
- Alipour Shahriar,
- Asghari Jafarabadi Mohammad,
- Farrin Nazila,
- Ostadrahimi Alireza
Appetite 2018 May 19. Epub 2018 May 19.
Nutrition Research Center, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address:
Obesity is a crucial public health problem worldwide and is considered as the main cause of many chronic diseases. The present study evaluated the effects of Oleoylethanolamide (OEA) supplementation on proximal proliferator-activated receptor-α (PPAR-α) gene expression, appetite sensations, and anthropometric measurements in obese people. This randomized, double-blind, placebo-controlled clinical trial was carried out on 60 healthy obese people in Tabriz, Iran, in 2016. Read More