23,314 results match your criteria Appendicitis
Medwave 2018 Dec 11;18(8):e7370. Epub 2018 Dec 11.
Proyecto Epistemonikos, Santiago, Chile; Centro Evidencia UC, Pontificia Universidad Católica de Chile, Santiago, Chile; Departamento de Medicina Interna, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.
Introduction: The treatment of acute appendicitis using laparoscopy reduces the risk of wound infection, hospitalization time and return to normal activity. However, it increases the risk of intra-abdominal abscess, which is one the main complications of complicated appendicitis.
Methods: We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. Read More
Asian J Endosc Surg 2018 Dec 11. Epub 2018 Dec 11.
Department of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Introduction: We conducted a prospective non-randomized comparison of children with uncomplicated appendicitis treated either by primary laparoscopic appendectomy (PLA) or by non-operative management (NOM) followed by interval laparoscopic appendectomy (ILA) if NOM was successful or emergency laparoscopic appendectomy (ELA) if NOM was unsuccessful.
Methods: Before 2015, all patients with uncomplicated appendicitis underwent PLA using a standard three-port technique. Postoperatively, piperacillin/tazobactam was administered until the white blood cell count was less than 10 000/μL and patients were afebrile. Read More
J West Afr Coll Surg 2017 Jul-Sep;7(3):94-115
Department of Surgery, National Hospital, Garki, Abuja, Nigeria.
Background: The known complications of appendicitis include perforated appendicitis with generalised peritonitis, appendiceal mass, appendiceal abscess, sepsis, adhesion formation and in a few occasions, small bowel intestinal obstruction.
Aim: To review published cases of intestinal obstruction due to appendicitis with a view to better understand the pathophysiology of this complication.
Methodology: A search of the literature in the MEDLINE database, using PubMed and OvidSP, Scopus, Google Scholar and Cochrane Databases with the following MeSH terms: was done. Read More
Surg Case Rep 2018 Dec 13;4(1):143. Epub 2018 Dec 13.
Department of General surgery, Redcliffe Hospital, Redcliffe, QLD, 4020, Australia.
Background: Femoral hernia accounts for 3% of all the hernias, and in 0.5-5% of cases, the appendix can migrate through the femoral hernia and is called de Garengeot hernia. It is a very rare condition, and the incidence of appendicitis in this type of hernia is as low as 0. Read More
Cir Esp 2018 Dec 9. Epub 2018 Dec 9.
Cirugía General y Digestivo, Hospital Universitario Los Arcos del Mar Menor, San Javier, Murcia, España.
Indian J Surg Oncol 2018 Dec 7;9(4):613-617. Epub 2018 Aug 7.
Parvarish Nursing Home, Andheri, Mumbai, Maharashtra India.
Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Read More
Hernia 2018 Dec 7. Epub 2018 Dec 7.
Department of Surgical Sciences, Uppsala University, 75185, Uppsala, Sweden.
Purpose: de Garengeot's hernia is a rare entity in which the appendix is located within a femoral hernia and is almost invariably encountered incarcerated in an emergency setting with concomitant appendicitis. In the literature, there are mostly single-case reports. The purpose of the present study was to perform a review of the literature to study the incidence, pathogenesis, demographics, clinical presentation, laboratory and radiological investigations, differential diagnosis, delay in diagnosis and treatment, operative findings, surgical technique, histological findings, the postoperative course, use of antibiotics, and complications regarding de Garengeot's hernia. Read More
Pediatr Surg Int 2018 Dec 7. Epub 2018 Dec 7.
Department of Pediatric Surgery, Charité, Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Purpose: We have recently shown that uncomplicated phlegmonous appendicitis is characterized by independent inflammatory patterns based on significant eosinophilia in children aged 7-17 years. However, clinical decision-making based on inflammatory values is not easy, especially due to the dynamics of inflammation over time. The present study was performed to evaluate the basic distinguishability of the inflammatory entities by laboratory values over time based on an extended patient number with children aged 0-17 years. Read More
Rom J Morphol Embryol 2018 ;59(3):939-943
Department of Pediatric Surgery, University of Medicine and Pharmacy of Craiova, Romania; Department of General Surgery, University of Medicine and Pharmacy of Craiova, Romania;
The acute abdomen with its many clinical aspects is not a condition that eludes pregnancy; acute appendicitis being the most frequently incriminated, but when it comes to its complication - peritonitis and the pregnant is a teenager, the cases cited in the literature are quite rare. We present the case of a 15-year-old teenager pregnant within 24 weeks admitted from the emergency department with the diagnosis of acute abdomen and operated for generalized peritonitis due to a perforated appendicitis. The microscopic analysis of the specimen indicated the presence of ulceration and extensive and deep and necrosis of the appendicle wall, the residual structures being dissected by a predominantly polymorphonuclear leukocytes inflammatory infiltrate associated with eosinophilic fibrinous deposits. Read More
Khirurgiia (Mosk) 2018 (10):73-75
Department of Surgery with course of endoscopy, Bashkir State Medical University of Healthcare Ministry of the Russian Federation, Ufa, Russia.
Surg Laparosc Endosc Percutan Tech 2018 Dec 10. Epub 2018 Dec 10.
Surgery, Hanyang University Guri Hospital, Hanyang University School of Medicine, Seoul, Korea.
Background: There have been reports of favorable results in patients with peritonitis who underwent laparoscopic surgery. The present study evaluated the outcomes of laparoscopic surgery in patients with pan-peritonitis.
Materials And Methods: We enrolled 148 patients who underwent open and laparoscopic surgery for pan-peritonitis between January 2015 and December 2017 at Hanyang University Guri Hospital. Read More
J Pediatr Surg 2018 Nov 7. Epub 2018 Nov 7.
Department of Paediatric Surgery, Alder Hey Children's Hospital, Liverpool, UK. Electronic address:
Aim: Despite evidence to suggest shorter durations of antibiotics are safe in complicated appendicitis, the practice has not been widely adopted in the UK. Our aim was to determine whether a clinical pathway that tailors antibiotics to clinical condition was safe and effective.
Methods: A new post-operative pathway (NewPath) was devised that reduced mandatory intravenous antibiotics for complicated appendicitis (perforated or gangrenous) from 5 to 3 days post-operatively, provided the child was apyrexial for >12 h and tolerating oral diet. Read More
Surg Infect (Larchmt) 2018 Dec 11. Epub 2018 Dec 11.
1 Cardinal Glennon Children's Medical Center , St. Louis, Missouri.
Background: No consensus exists regarding duration of antibiotic therapy for complicated appendicitis treated with interval appendectomy. We hypothesized that more than two weeks of antibiotic therapy does not decrease complication rates in asymptomatic patients.
Patients And Methods: A retrospective review of all patients with complicated appendicitis treated with interval appendectomy from 2010-2015 was performed. Read More
Ugeskr Laeger 2018 Nov;180(48)
Appendicitis is a common condition, which is often seen by the general practitioners as well as in the emergency departments. It is normally treated with laparoscopic appendectomy. This review gives an overview of the long-term surgical complications ileus and incisional hernia and of the impact of appendicitis and appendectomy on female fertility. Read More
Pediatr Surg Int 2018 Dec 3. Epub 2018 Dec 3.
Department of Surgery, Children's Mercy Hospital, 2401 Gillham Road, 64108, Kansas City, MO, USA.
Background: Post-operative intra-abdominal abscess (PIAA) is the most common complication after appendectomy for perforated appendicitis (PA). Typically, intravenous antibiotics by a peripherally inserted venous catheter are utilized to treat the abscess. We sought to evaluate the role of oral antibiotics in this population. Read More
Ann Med Surg (Lond) 2018 Dec 9;36:168-172. Epub 2018 Nov 9.
UCL Medical School, UCL, Research Department of Medical Education, Room GF/664, Royal Free Campus, Hampstead, London, NW3 2PR, UK.
Background: Appendicitis is a medical condition that causes painful inflammation of the appendix. For acute appendicitis, appendectomy is immediately required as any delay may lead to serious complications such as gangrenous or perforated appendicitis with or without localized abscess formation. Patients who had appendectomy for complicated appendicitis are more prone to develop post-operative complications such as peritoneal abscess or wound infection. Read More
J Pak Med Assoc 2018 Dec;68(12):1854-1858
Jinnah Sindh Medical University, Karachi.
Pheochromocytoma, a rare tumour, arises mainly in the adrenal gland. It consists of chromaffin cells or sympathetic para-ganglia if extra-adrenal. It is an occurrence of rare nature with an incidence of two to eight cases per million annually. Read More
Gynecol Obstet Fertil Senol 2018 Nov 28. Epub 2018 Nov 28.
Clinique Tivoli-Ducos, 33000 Bordeaux, France. Electronic address:
J Surg Res 2019 Jan 26;233:8-19. Epub 2018 Jul 26.
Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Background: Transferred emergency general surgery (EGS) patients have increased morbidity, mortality, and costs, yet little is known about the characteristics of such transfers. Increasing specialization and a decreasing general surgery workforce have led to concerns about access to care, which may lead to increased transfers. We sought to evaluate the reasons for and timing of transfers for EGS diagnoses. Read More
J Surg Res 2019 Jan 17;233:100-103. Epub 2018 Aug 17.
Department of Surgery, The Children's Mercy Hospital, Kansas City, Missouri. Electronic address:
Background: In some institutions, urinary catheters (UCs) have been placed in all patients receiving opioid patient-controlled analgesia (PCA) because of the increased incidence of urinary retention. Our institutional data demonstrated no UC replacements in 48 children who had PCA for perforated appendicitis who had their catheters removed before discontinuation of the PCA. As part of a quality improvement initiative, we discontinued the practice of requiring UC with PCA for perforated appendicitis. Read More
J Pediatr Surg 2018 Nov 7. Epub 2018 Nov 7.
Division of General, Thoracic and Fetal Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address:
Aim Of The Study: Pediatric surgery trainees at our program are allowed to perform unsupervised laparoscopic appendectomies during their last year of training to promote independent operative decision-making skills. We reviewed the outcomes of laparoscopic appendectomies done by senior trainees without supervision and compared them to experienced pediatric surgeons.
Methods: We reviewed 500 laparoscopic appendectomies performed without supervision by the last 10 pediatric surgery trainees during their last year of training (first 50 cases of each trainee). Read More
PLoS One 2018 5;13(12):e0208151. Epub 2018 Dec 5.
Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA, United States of America.
The communities of beneficial bacteria that live in our intestines, the gut microbiome, are important for the development and function of the immune system. Bacteroides species make up a significant fraction of the human gut microbiome, and can be probiotic and pathogenic, depending upon various genetic and environmental factors. These can cause disease conditions such as intra-abdominal sepsis, appendicitis, bacteremia, endocarditis, pericarditis, skin infections, brain abscesses and meningitis. Read More
J Trauma Acute Care Surg 2018 Dec 3. Epub 2018 Dec 3.
Professor of Medicine and Emergency Medicine, Department of Emergency Medicine (and Department of Medicine, Division of Infectious Diseases), Olive View-UCLA Medical Center, 14445 Olive View Drive, North Annex, Sylmar, CA 91342.
Background: Meta-analyses and a recent guideline acknowledge that conservative management of uncomplicated appendicitis with antibiotics can be successful for patients who wish to avoid surgery. However, guidance as to specific management does not exist.
Methods: PUBMED and EMBASE search of trials describing methods of conservative treatment was conducted according to PRISMA guidelines. Read More
Ulus Travma Acil Cerrahi Derg 2018 Nov;24(6):557-562
Department of General Surgery, Okmeydanı Training and Research Hospital, İstanbul-Turkey.
Background: The Alvarado score (AS) and the Appendicitis Inflammatory Response score (AIRS) were developed to diagnose acute appendicitis (AA). The aim of this study was to evaluate the severity of AA using the AS and the AIRS tools.
Methods: Patients who presented between January 2016 and December 2017 and underwent surgery for AA and who had a preoperative AS and AIRS value were evaluated retrospectively. Read More
Ulus Travma Acil Cerrahi Derg 2018 Nov;24(6):552-556
Department of General Surgery, İstanbul University İstanbul Faculty of Medicine, İstanbul-Turkey.
Background: The aim of this study was to compare the obstetric and surgical outcomes of laparoscopic appendectomy (LA) and open appendectomy (OA) performed for pregnant women at a single center. It was the hypothesis of this study that there would be no significant difference in the results.
Methods: The medical records of 57 consecutive pregnant women who underwent an appendectomy between January 2009 and September 2018 were reviewed retrospectively. Read More
Ulus Travma Acil Cerrahi Derg 2018 Nov;24(6):545-551
Department of General Surgery, Sakarya University Training and Research Hospital, Sakarya, Turkey.
Background: The Karaman score is a novel diagnostic scoring system consisting of 6 parameters. The aim of the present study was to assess the diagnostic performance of the Karaman score in comparison with the Alvarado score.
Methods: A total of 200 patients who underwent an appendectomy were enrolled in the study (research registry number: 2290). Read More
Ulus Travma Acil Cerrahi Derg 2018 Nov;24(6):539-544
Department of Emergency, University of Health Sciences, Haseki Training and Research Hospital, İstanbul-Turkey.
Background: The aim of this study was to investigate the prognostic value of irisin by examining the serum level of this smooth muscle protein in patients presenting at the emergency department (ED) with acute abdominal pain.
Methods: This research was performed as a single-center, prospective, cross-sectional study. In all, 213 adult patients presenting at the ED with acute abdominal pain and 140 healthy controls were enrolled. Read More
ANZ J Surg 2018 Dec;88(12):1222-1223
Department of Surgery, The University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Surg Endosc 2018 Dec 4. Epub 2018 Dec 4.
Department of General Surgery, Shaare Zedek Medical Center, Jerusalem, Israel.
Background: Accurate and timely diagnoses of acute appendicitis (AA) during pregnancy avoids maternal and fetal morbidity and mortality. We present our experience of using an initial transabdominal ultrasound (US) performed at presentation to diagnose AA in pregnant patients as well as the value of a delayed repeat study in those who remain equivocal. We explore the sensitivity and specificity of this algorithm as well as the maternal and fetal safety of this approach. Read More
Mater Sociomed 2018 Oct;30(3):215-220
King Abdulaziz University, Medical School, Jeddah, Saudi Arabia.
Introduction: Acute Appendicitis is the most common emergent abdominal surgery worldwide. diagnosis based on clinical assessment, laboratory and radiological investigations and appendectomy is the treatment of choice. Removing a normal appendix is a relatively common surgical issue, defined as negative appendectomy (NA). Read More
Int J Surg Case Rep 2018 Nov 16;54:34-38. Epub 2018 Nov 16.
Department of Surgery, Palmetto Healthcare System, University of South Carolina Medical School, 2 Medical Park Road, Columbia, SC 29203, United States. Electronic address:
Introduction: A colonic metastasis from infiltrating breast ductal carcinoma is a rare phenomenon in the literature, especially in a male.
Presentation Of Case: We present a rare case of a 55-year-old male with a past medical history of breast cancer who presented with signs and symptoms of appendicitis. A computed tomography (CT) scan revealed acute appendicitis in addition to a 2. Read More
Ann Ital Chir 2018 Nov 29;7. Epub 2018 Nov 29.
Purpose: In this study, we compared the endocrine and cytokine reaction of the patients which laparoscopic and conventional appendectomy was done for acute appendicitis.
Materials And Method: 50 patients who were operated for acute appendicitis in Ankara Atatürk Research and Training Hospital between the dates December 2013 and February 2014 were enrolled and grouped as either laparoscopic or conventional. Serum ACTH, IL-6 and CRP levels were obtained at induction of anesthesia and postoperative 6th hour. Read More
Ann Med Surg (Lond) 2018 Dec 20;36:239-241. Epub 2018 Nov 20.
Caboolture Hospital, 120 McKean Street, 4510, Queensland, Australia.
Introduction: Acute appendicitis in older adults is relatively uncommon and could be the first presentation of an underlying colorectal carcinoma. Colonoscopy in these individuals affords the opportunity for earlier diagnosis and treatment. The finding of increased rates of colorectal cancer (CRC) with older patients who have had appendicitis was supported by a number of small studies and case reports in the early 1980s. Read More
Am J Surg 2018 Nov 27. Epub 2018 Nov 27.
Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland. Electronic address:
Background: The aim of this study was to assess outcomes of octogenarians undergoing emergency abdominal surgery (EAS).
Methods: Octogenarians undergoing EAS 12/2011-12/2016 were retrospectively analysed. The outcomes were assessed by univariable and multivariable regression analysis. Read More
Medicine (Baltimore) 2018 Nov;97(48):e13294
Department of Laboratory, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Rationale: The presence of purpura is a compulsory criteria for the diagnosis of Henoch-Schönlein purpura (HSP). Typical purpura of HSP is distributed symmetrically over the extensor surfaces of the lower limbs, buttocks, and forearms with the occasional involvement of trunk and face in children. It occurs only involving the bottom of the feet has never been reported. Read More
BMJ Paediatr Open 2018 9;2(1):e000341. Epub 2018 Nov 9.
Division of Pediatric Surgery, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Introduction: Many children with acute abdominal pain and suspicion of appendicitis are diagnosed with constipation. Nevertheless, it can be difficult to differentiate between acute constipation and acute appendicitis because of similar symptoms and lack of diagnostic criteria. Consequently, constipation is often missed despite repeated consultations at the emergency department. Read More
ANZ J Surg 2018 Nov 29. Epub 2018 Nov 29.
Department of General Surgery, Singapore General Hospital, Singapore.
J Cancer Res Ther 2018 Oct-Dec;14(6):1355-1360
Department of Radiology, Health Science University, Umraniye Education and Research Hospital, Istanbul, Turkey.
Aims: Appendiceal mucocele (AM) is a rare pathology, and its reported incidence is 0.3% in all appendectomy specimens. Here, we report a case series of AM and make a brief review of literature. Read More
Cochrane Database Syst Rev 2018 11 28;11:CD001546. Epub 2018 Nov 28.
Institute for Research in Operative Medicine (IFOM) - Department for Evidence-based Health Services Research, University Witten/Herdecke, Ostmerheimer Str. 200 (Building 38), Cologne, Germany, 51109.
Background: The removal of the acute appendix is one of the most frequently performed surgical procedures. Open surgery associated with therapeutic efficacy has been the treatment of choice for acute appendicitis. However, in consequence of the evolution of endoscopic surgery, the operation can also be performed with minimally invasive surgery. Read More
JAMA Surg 2018 Nov 28. Epub 2018 Nov 28.
Department of Surgery, VA Boston Healthcare System, West Roxbury, Massachusetts.
JAMA Surg 2018 Nov 28. Epub 2018 Nov 28.
Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.
Importance: The step after conservative treatment of periappendicular abscess arouses controversy, ranging from recommendations to abandon interval appendectomy based on low recurrence rates of the precipitating diagnosis to performing routine interval appendectomy owing to novel findings of increased neoplasm risk at interval appendectomy. To our knowledge, there are no randomized clinical trials with sufficient patient numbers comparing these treatments.
Objective: To compare interval appendectomy and follow-up with magnetic resonance imaging after initial successful nonoperative treatment of periappendicular abscess. Read More
Iran J Microbiol 2018 Aug;10(4):208-214
Nizam's Institute of Medical Sciences Panjagutta, Hyderabad, Telangana, India.
Background And Objectives: Intra-abdominal infections (IAIs) include a wide spectrum of pathological conditions, ranging from uncomplicated appendicitis to fecal peritonitis .The resulting infections should be diagnosed early and treated based on the organism isolated and its susceptibility. In this study the bacteriological profile and antimicrobial resistance pattern of intra-abdominal infections was analyzed. Read More
J Pediatr Surg 2018 Nov 7. Epub 2018 Nov 7.
Department of Surgery, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada; Division of General Surgery, St. Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, Ontario, L8N 4A6, Canada. Electronic address:
Background/purpose: Appendiceal perforation significantly impacts the outcomes of pediatric appendicitis. While socioeconomic status affects perforation risk in the United States, these effects should dissipate in a universal healthcare system. The specific spatial patterns associated with perforation have also never been delineated. Read More
Int J Surg Case Rep 2018 Nov 13;53:377-380. Epub 2018 Nov 13.
Department of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Introduction: Neurofibromas are a characteristic of the autosomal dominant disorder Neurofibromatosis type 1 (NF1), also known as von Recklinghausen's disease. Appendiceal neurofibromas are extremely rare, and low-grade appendiceal mucinous neoplasms (LAMNs) have not previously been reported in NF1.
Presentation Of Case: A 62-year-old man with NF1 was scheduled for elective surgical treatment of an asymptomatic, enlarged and diffusely thickened appendix that remained after curative antimicrobial treatment of acute appendicitis. Read More
J West Afr Coll Surg 2017 Oct-Dec;7(4):120-127
Assistant Professor Histopathology, Shifa International Hospital, Islamabad, Pakistan.
Mucocele of the appendix is an uncommon disease in which there is cystic dilatation of the appendix caused by mucus secretion and usually associated with benign or malignant causes. Preoperative diagnosis is difficult as the patient presents with non-specific clinical symptoms. We report a case of mucocele of the appendix with elevated serum carcinoembryonic antigen (CEA) - a condition sparsely reported in literature. Read More
Turk J Surg 2018 Nov 20:1-3. Epub 2018 Nov 20.
Department of Surgery, Hamadan University of Medical Sciences, Hamadan, Iran.
Objective: Despite the recent use of computed tomography scan and diagnostic laparoscopy, acute appendicitis is still highly misdiagnosed. Timely diagnosis of acute appendicitis is more crucial in children and elderly patients because of vague symptoms and rapid progression to perforation in these age groups, which may result in high rates of morbidity and mortality. The aim of the present study was to find the diagnostic values of procalcitonin and interleukin 6 (IL-6) for diagnosing acute appendicitis in our center. Read More
Turk J Surg 2018 Nov 20:1-5. Epub 2018 Nov 20.
Department of General Surgery, Bursa Yüksek İhtisas Training and Research Hospital, İstanbul, Turkey.
Objective: Appendiceal tumors are rare and mostly present as acute appendicitis. Its estimated lifetime prevalence has been reported as 8%, and the annual incidence is approximately 0.1% in Western countries. Read More
Am J Emerg Med 2018 Nov 17. Epub 2018 Nov 17.
Department of Surgery, University of Pamukkale, Denizli, Turkey.
Simple bone cyst (SBC) also known as unicameral bone cyst is a benign, radiolucent bone lesion that is seen commonly in childhood. These lesions are usually found incidentally although pain and swelling can be seen. The most common complication is a pathological fracture, and this is often the cause of presentation. Read More